1337081 . 九、發明說明: 【發明所屬之技術領域】 本發明係有關於一種個人局部肢體清潔殺菌劑, 特別係種包含二氧化氣及保關之不需水的手部 清潔殺菌劑’藉由二氧化氣及保濕劑可同時達到直接 於手部表面清潔、殺菌、消毒及保護皮膚之功效。 【先前技術】 ㈣li—般傳染病的傳播途徑之中,最常見的就是 接觸傳…非典型料(SARS)為例,根據世界衛 =組織的報告,一小滴患者的痰液,有超過一億個病 :,當患者掩口咳料,其雙手必定沾滿危險的病 毒。現代密集的都市生活,擁擠的公共交通,頻繁的 商務活動,都是疾病快速傳播的管道。例如:流行性 感冒、非典型肺炎,病毒性結膜炎等,都會由^他人 握手或接觸公共物品(例如:門把手、鈔票、電梯扶 手等),進而以未消毒的雙手接觸自己的眼、口包鼻而 被傳木。所以’時時消毒雙手是疾病流行期間重要的 自保之道。個人防疫工作首重洗手·,勤加洗手是防止 接觸傳染的理想方式,㉟常以肥皂清洗雙手,能有效 去除手上可能沾染的病毒,切斷病毒進入口、鼻的途 徑。然而’傳統洗手方式’在時間上的需求較多,常 因太忙碌而忽略未注意;在舒適方面因為經常沖洗和 使用洗劑讓皮膚易受刺激而導致乾燥不適、皮膚粗糙 1337081 -- 不柔順或過敏情形等;在設備方面因洗手台位置遠不 方便、洗手台數量不足或設計不適當等;在觀念方面 因不知正確的洗手方式、缺乏洗手知識指引、不覺得 自己的手薪等。因此’酒精性免水洗手劑之產品克服 了上述之不方便性’在無法用水洗手的時候,酒精性 免水洗手劑就是最能應急的隨身清潔劑,只要滴一滴 酒精性免水洗手劑於手上’雙手互相搓揉至洗手劑完 _ 全揮發至乾即能隨時做好手部消毒殺菌的工作。 目前市面上、實驗室或醫院清潔手部時皆是會以 酒精性免水洗手劑來清潔消毒。雖然,酒精已是較安 全的消毒劑,但酒精含量需至75%及長期使用含酒精 之免水洗手劑仍會引起皮膚的乾燥與刺激缺點,又酒 精是屬可燃性物質其燃點範圍是21_24t,因此,放置 位置需遠離高溫或可燃之處。所以,對酒精性免水洗 I 手劑產品的安全性需多做考t。 首先須對二氧化氣的歷史做個了解,在十八世紀 五十年代初期已被大家所認識二氧化氯可作為廣泛使 2的殺菌消毒劑。許多研究證明,二氧化氣的殺菌消 毒面廣、效果好、作用速度快、持續時間長、劑量 ]反應產物热毒、對人體無刺激。世界衛生組織 (WHO)將穩定的二氧化氣列為ai級高效安全消毒 ^美國%保局批准應用於醫院、實驗室、醫藥部門 環境的消毒、防霉;醫院牙醫儀器設備的消毒、防 1337081 . 霉;口腔漱口消毒、防臭;牙醫浮石消毒、食品表面 的最終淋洗;未切開、未剝皮蔬菜的消毒;農產品、 水果、飲用水的消毒;動植物飼養場的消毒。美國食 品藥物管理局批准可用於食品工業設備、器具的消 毋,亦可作為間接添加劑。美國農業部批准二氧化氣 可用於肉製品,家禽加工廢控制微生物、徽菌的殺菌 劑。日本的食品衛生法規將二氧化氣列入食品添加 • 劑、麵粉改良劑。目前歐美已經有數百家水廠採用二 、 氧化氣處理飲用水。美國、日本、加拿大等國都分別 頒佈不同法令、法規強制規定在某些方面必須使用穩 定性二,化氣。而二氧化氣之應用是國際上公認性能 優良、高效安全之殺菌消毒劑,水質淨化劑,食品保 鮮劑和除臭防腐劑。 有鑑於傳統洗手方式及酒精性洗手劑之缺點,本 ^月人進而研九出一種含二氧化氣之個人局部肢體清 •潔殺菌劑,只需極少份量即兼具有消毒、殺菌、洗 手、5蔓膚之功效。 【發明内容】 ^本=明之主要目的,在於提供一種個人局部肢體 /月S殺菌^,其主要係藉由二氧化氣之強效殺菌力達 到瞬間消毒、殺菌之作用者。 本發明解決先前技術所使用之技術手段,乃在於 利用-種「個人局部肢體清潔殺菌劑」,其係包含二氧 1337081 化氣殺菌消毒劑、保濕劑及成型劑,藉由二氧化氣達 到消毒、殺菌之功效,而保濕劑可提供皮膚的柔軟與 平滑感,使得使用者可在缺水狀態或其餘環境的限制 下’達到清潔消毒手部或物體表面之功效。 有關本發明「個人局部肢體清潔殺菌劑」上述目 的、功效及特點,將舉出一具體實施例詳細說明如 下,俾對本發明進一步瞭解。 【實施方式】 本發明之個人局部肢體清潔殺菌劑,其成份至少 包含一成型劑、一殺菌消毒劑及一 pH值調節劑;其 中♦ S玄成型劑係為尚分子聚合物,其係由水溶性高分 子膠與水混合之膠狀溶液,該水溶性高分子膠之濃度 範圍在0.1-10 %之間,且其種類可為纖維素膠 (Cellulose Gum )、亞拉伯膠(Gum Arabic/Gum Acacia )、曱基纖維素(Methylcellulose,MC )、果膠 (Pectin )、三仙膠(xanthan Gum )或卡波姆 (Carbomer )之其中一項或其他等效物者;該殺菌消 毒劑係為二氧化氯(Chlorine dioxide ),其濃度範圍在 H7.5mM (莫耳濃度)之間者;該pH值調節劑可為 氫氣化鈉(NaOH)、破酸(phosphoric acid)、鹽酸 (hydrochloric acid )、石肖酸(nitric acid )溶液或其他 等效物,其濃度範圍為適量者。 所述之個人局部肢體清潔殺菌劑成分中亦可增加 8 1337081 ,,保濕劑及香精;其中該保濕劑係為一親水性保濕劑, 其可為多元醇保濕劍或其他等效物,其多元醇保渴劑 可為丙三醇(俗稱甘油Glyeedn)或其他等效物,而 其濃度範圍在0小10%之間;該香精可為茶樹油㈤ tree oil) ’其濃度範圍在〇1_15%之間。 由上述成分組成之個人局部肢體清潔殺菌劑,其 實際製作時係先將水溶性高分子膠加入水中配置成 • 〇.1-0.8%之成型劑,並以攪拌器於室溫下攪拌至溶液 成均勻之膠狀物,隨後加入0.5_15%茶樹油(Tea tree oil)及1-10%甘油(Glycerin)保濕劑,此時整體溶 液之pH值會依所加入之水溶性高分子膠種類不同而 呈現不同之酸性或鹼性狀態,此時則必須加入適量之 pH值調節劑’以將整體溶液調整至pH值=5 5±〇 5 之微酸性狀態,例如本實施例中所加入之水溶性高分 子耀·係為卡波姆(Carbomer ),故整體溶液會呈現在 PH = 2之強酸狀態,因此為了符合人體之皮膚特質, 必須加入0.M2N (克當量)之氫氧化鈉溶液 (NaOH),以調整pH值至5.5土0· 5之微酸性狀態, 俾達到溫和不刺激之效果,最後再加入〇.3_7 5mM (莫耳〉農度)之二氧化氣(Chlorine dioxide),再次混 合均勻即可完成本發明個人局部肢體清潔殺菌劑之製 作者。 藉此’本發明之個人局部肢體清潔殺菌劑配方於 丄· 實際使用 中的蛋時’其二氧化氣在水中解離後’可和細胞膜 白質成分產生反應而破壞細菌的新陳代謝,其 可月t*步驟如下: (1)殺菌成分滲透進入細胞膜。 C 2 1 此一成分和細胞質中的物質產生化學反應, 形成有毒物質而消滅微生物。 (3)另一殺菌機制可能是活性氣破壞蛋白質中雙 瓜、’使蛋白質失去活性,進而使細菌不能生長或 死亡。 亦二氧化氯在多種常用消毒劑中是高效、強力殺菌 在相同時間内達到同樣的殺菌率所需的二氧化氣 濃度是最低的。當細菌濃度在105〜106CFU/mL時, ppm的一氧化氣作用五分鐘後即可殺菌9外以上的 異營菌’仙12 λΜ寺殺菌率保持不變。由於經急性口 服毒性試驗得知無毒、無刺激性,二氧化氣消毒滅菌 屬實際無毒級產品,用其消毒的水體不會對口腔黏 膜、皮膚和頭ϋ產生損傷’其在急性毒性和遺傳毒理 學上都是絕對安全的。二氧化氣的安全、多功能不與 水體中的有機物作用生成三齒甲烧等致癌物質,對高 等動物細胞、***及染色體無致癌、致畸、致突變作 用’並且二氧化氣使用鳌很低’因此用二氧化氣消毒 十刀女王無殘留毋性,係為一符合安全性之清潔配 方者。 1337081 · 【圖式簡單說明】 益 【主要元件符號說明】1337081 . IX. Description of the invention: [Technical field to which the invention pertains] The present invention relates to a personal topical body cleansing bactericide, in particular to a hand-cleaning bactericide containing hydrogen dioxide and a water-free hand-protecting agent. Dioxide gas and humectant can simultaneously clean, sterilize, disinfect and protect the skin directly on the surface of the hand. [Prior Art] (4) Among the routes of transmission of li-like infectious diseases, the most common one is the contact transmission... atypical material (SARS), for example, according to the report of the World Health Organization, a small drop of sputum has more than one Billion disease: When a patient covers a cough, his hands must be covered with a dangerous virus. Modern and dense urban life, crowded public transportation, and frequent business activities are all channels for the rapid spread of disease. For example, influenza, atypical pneumonia, viral conjunctivitis, etc., will be shaken by other people or contact with public goods (such as door handles, banknotes, elevator handrails, etc.), and then contact their eyes and mouth with unsterilized hands. The nose is passed and the wood is passed. Therefore, disinfecting hands from time to time is an important way to protect yourself during the epidemic. Personal anti-epidemic work is the first to wash your hands. It is an ideal way to prevent contact with infection. 35 Wash your hands with soap. It can effectively remove the virus that may be contaminated on your hands and cut off the path of the virus into the mouth and nose. However, the 'traditional hand washing method' has more demand in time, often too busy to ignore and not pay attention; in comfort, because of frequent washing and using lotion to make the skin susceptible to irritation, resulting in dry discomfort, rough skin 1337081 -- not supple Or allergic conditions, etc.; in terms of equipment, the location of the sink is far from convenient, the number of sinks is insufficient or the design is not appropriate; in terms of concept, I don’t know the correct way to wash my hands, lack the guidance of hand washing knowledge, and don’t feel my own salary. Therefore, the product of 'alcohol-free water-based hand washing agent overcomes the above inconvenience'. When it is not possible to wash hands with water, alcohol-based water-free hand washing agent is the most emergency portable cleaning agent, as long as a drop of alcohol-based water-free hand washing agent is applied. Hands on the hands of each other until the hand washing agent _ all volatile to dry can be done at any time to do the hands disinfection work. At present, when cleaning hands on the market, in the laboratory or in hospitals, alcohol-based water-free hand sanitizers are used for cleaning and disinfection. Although alcohol is a safer disinfectant, the alcohol content needs to be 75%. The long-term use of alcohol-free water-free hand washing agent will still cause dryness and irritation of the skin. Alcohol is a flammable substance and its ignition range is 21_24t. Therefore, the location should be kept away from high temperatures or flammable places. Therefore, the safety of alcohol-free water-washing I-hand products needs to be tested. First of all, we must understand the history of dioxide gas. In the early 1950s, we were recognized by everyone that chlorine dioxide can be used as a disinfectant for a wide range of applications. Many studies have proved that the sterilization and disinfection of dioxide gas is wide, the effect is good, the action speed is fast, the duration is long, the dose is low, and the reaction product is not irritating to the human body. The World Health Organization (WHO) lists stable sulfur dioxide as ai-class high-efficiency and safe disinfection. ^ US% insurance bureau approved for disinfection and mildew prevention in hospitals, laboratories, and medical departments; disinfection and prevention of hospital dental equipment and equipment 1337081 Mold; oral mouthwash disinfection, deodorization; dentist pumice disinfection, food surface final leaching; uncut, unpeeled vegetables disinfection; agricultural products, fruits, drinking water disinfection; animal and plant breeding ground disinfection. Approved by the US Food and Drug Administration for use in food industry equipment and appliances, or as an indirect additive. The US Department of Agriculture approves the use of dioxide gas for meat products, poultry processing waste control microorganisms, and fungicides for the bacteria. Japan's food hygiene regulations include dioxide gas as a food additive, flour improver. At present, hundreds of water plants in Europe and the United States have used oxidizing gas to treat drinking water. The United States, Japan, Canada and other countries have separately promulgated different laws and regulations and mandated that in some respects, stability must be used. The application of dioxide gas is recognized internationally as an excellent, efficient and safe disinfectant, water purifier, food preservative and deodorant preservative. In view of the traditional hand washing methods and the shortcomings of alcoholic hand-washing agents, this person has further researched and developed a personal body cleansing and bactericidal agent containing dioxide gas, which requires only a small amount of disinfection, sterilization, and hand washing. 5 effect of the skin. SUMMARY OF THE INVENTION The main purpose of the present invention is to provide a personal local limb/month S sterilization, which is mainly caused by the strong sterilization force of the dioxide gas to achieve the role of instant disinfection and sterilization. The technical means used in the prior art to solve the prior art is to utilize a "personal local limb cleansing bactericide" comprising a dioxin 13307081 sterilizing agent, a humectant and a forming agent, which is sterilized by a oxidizing gas. The effect of sterilization, and the moisturizing agent can provide the softness and smoothness of the skin, so that the user can 'clean and disinfect the hand or the surface of the object in the state of lack of water or the rest of the environment. The above-mentioned objects, functions and features of the "personal local body cleansing and bactericidal agent" of the present invention will be described in detail with reference to the following detailed description. [Embodiment] The personal skin cleansing and bactericidal agent of the present invention comprises at least a molding agent, a disinfectant and a pH adjusting agent, wherein the ♦ S-formant is a molecular polymer which is water-soluble. A colloidal solution of a polymer gel mixed with water. The concentration of the water-soluble polymer gel ranges from 0.1 to 10%, and the type thereof may be Cellulose Gum or Gum Arabic. Gum Acacia ), Methylcellulose (MC), Pectin, xanthan Gum or Carbomer, or other equivalents; Chlorine dioxide, the concentration range is between H7.5 mM (mole concentration); the pH regulator can be sodium hydride (hydrogen phosphate), phosphoric acid, hydrochloric acid (hydrochloric acid) ), a solution of nitric acid or other equivalents in a concentration range of the appropriate amount. The personal local body cleansing bactericidal ingredient may also add 8 1337081, a moisturizer and a fragrance; wherein the humectant is a hydrophilic moisturizer, which may be a polyol moisturizing sword or other equivalent, and its plural The alcohol quenching agent may be glycerol (commonly known as glycerin Glyeedn) or other equivalents, and its concentration ranges between 0 and 10%; the flavor may be tea tree oil (5) tree oil) 'the concentration range is 〇1_15% between. The personal body cleansing and bactericidal agent composed of the above components is actually prepared by adding a water-soluble polymer glue to water to prepare a molding agent of 1-.1-0.8%, and stirring the solution to a solution at room temperature with a stirrer. Form a uniform gel, then add 0.5_15% Tea tree oil and 1-10% Glycerin humectant. At this time, the pH value of the whole solution will vary depending on the type of water-soluble polymer glue added. In the case of different acidic or alkaline states, it is necessary to add an appropriate amount of pH adjuster to adjust the whole solution to a slightly acidic state of pH=5 5±〇5, such as water soluble in the present embodiment. The polymer ray is Carbomer, so the whole solution will be in a strong acid state of PH = 2, so in order to meet the skin characteristics of the human body, it is necessary to add 0.M2N (gram equivalent) of sodium hydroxide solution ( NaOH), to adjust the pH to a slightly acidic state of 5.5 soil 0, 5, to achieve a mild and non-irritating effect, and finally add 〇.3_7 5mM (Moor > agriculture) of chlorine dioxide (Chlorine dioxide), again The invention can be completed by mixing uniformly Local human limb-cleaning of the fungicide. Therefore, the 'individual topical body cleansing and bactericidal agent of the present invention is formulated in the 实际· the egg in actual use', after the dissociation of the oxidizing gas in the water, can react with the white matter component of the cell membrane to destroy the metabolism of the bacteria, which can be monthly t* The steps are as follows: (1) The sterilizing component penetrates into the cell membrane. C 2 1 This component chemically reacts with substances in the cytoplasm to form toxic substances and destroy microorganisms. (3) Another bactericidal mechanism may be that the active gas destroys the double melon in the protein, 'deactivates the protein, and the bacteria cannot grow or die. Also, chlorine dioxide is highly effective and strong in many common disinfectants. The concentration of dioxide required to achieve the same sterilization rate in the same time is the lowest. When the concentration of bacteria is 105~106CFU/mL, the bactericidal rate of the citric gas can be sterilized for more than 9 minutes after the action of ppm of oxidizing gas. Because it is non-toxic and non-irritating through acute oral toxicity test, the disinfection and sterilization of CO2 is an actual non-toxic product. The water disinfected by it will not cause damage to oral mucosa, skin and head lice. It is acutely toxic and genetically toxic. It is absolutely safe in science. The safety and versatility of the dioxide gas does not interact with organic matter in the water to produce carcinogens such as tridentate and burn, and is not carcinogenic, teratogenic or mutagenic to higher animal cells, sperm and chromosomes, and the use of sulphur dioxide is very low. 'Therefore, the use of sulfur dioxide to sterilize the ten-knife queen has no residue, and it is a safety formula. 1337081 · [Simple description of the diagram] Benefits [Main component symbol description]