TWI260226B - Complex prescription of Chinese medicine for the treatment of extensive cancer - Google Patents

Abstract

The cancers are classified as three types by the originator based on this principle: (1) allergy type of the upper digestive tract, (2) principle type in liver and gland, (3) relation type of the lymph node. Extensive in this application means the relation type of the lymph node which includes many cancers. A complex prescription of Chinese medicine for the treatment of extensive cancer, or cancer of relation type of the lymph node. The ingredients of this complex prescription are Pilose asiabell root, Astragalus root, Coix seed, Eupatorium, Tangerine peel, Justicia, Prunella spike, Serissa serissoides, Capejasmine fruit, Forsythia fruit, Red peony root, Rhubarb, Blister beetle, Oldenlandia, Polygonum perfoliatum, Subprostrate sophora root, Shrubalthea bark, Rhizome of arisaema, Chinese Lobelia, Ampelopsis, Globethistle, Pyrrosia leaf, Frankincense, Myrrh, Paris chinensis franch, Patrinia, Dahurian angelica root, Belamcanda rhizome, Dandelion herb, Lemmaphyllum microphyllum, Gleditsia spine, Pubescent angelica root, Chinese Ephedra, and Cimicifuga rhizome. The extraction is improved and it also adopts Indian Bread (Poria), an effective cancer medicine, as excipient. The invention objective is to provide a complex prescription of Chinese medicine for the treatment of extensive cancer and the relevant new ideas, new theories, and new references. The new treatment concerning changeable cancer environment will destroy the old mode against, destroying or extinguishing cancer cells to develop a new way in the treatment of cancer through traditional Chinese medicine. Clinical tests indicate that this sophisticated, rational and scientific new method can obtain comparatively ideal therapeutic effects on extensive lymph-node-related cancers, e.g. lung cancer, lymphoma, nasopharyngeal cancer, bowel cancer, bladder cancer, ovarian cancer, bone cancer, etc.

Description

12602261260226

創新理論」 舊有「抗癌」理論的實踐，並不能突破瓶頸，提升 效率，是以發明人乃創立了「變易癌環境」的新療法，麯 過多年實踐、改進、試驗的結果，已可證明預期的高療效， 5然而，此療法源自發明人連貫性的新理論，為使理解、 願敝帚自珍而予作概要說明。 該連貫性新理論依序是：「物之生、壯、老、死％ 「物勢形成環境」論，癌之「周環病理」論，「六大要:之 癌病理與論治」，以及癌之「類型機理」論中的「癌種轉移」 1〇論等等；凡此新理論，皆固有中華醫藥論據的延伸與創革，」 它的特徵是融入哲學理念，應用了中國古代哲學家老子、 李聃（約在公元前5 8 0年）的著述，依據自然的物理現 象與規則，抉發出與治癌相關的論述。 百先，「物之生、壯、老、死」論（參閱發明人著作權 15登記證書號2〇〇1-Α·〇342「廿-世紀癌症治療新道路」、第 二章前段），在於說明，凡是能夠繁衍同類後代的物體，是 為「自生物」，也就是現代所稱的「生物」；生物皆不可能 長生不老」，其正常的生態必然要有「出生（繁衍）、茁 壯、老弱、病亡」的過程；「癌細胞」亦會在機體内消失。 20 4 了達成上述假設方法，就必要先行暸解癌細胞生、 壯、老、死的實況，X其是病體環境中、冑易的過程與原 因；從此而再涉及了「物勢形成環境」論（參閱發明人著 作權登紐«歷·Α_〇342「* —世紀癌症治療新道路」 第二章後段）。在此理論中，將可發覺生物生存的一種共通 -6- 1260226 _· , 發明說明/續頁 哇’那就是·「生物之生存，在它各類、綱、科、屬之關聯 中，皆有各自的，一定的環境適應程度」，此環境適應程度 與物之生、壯、老、死有了密切關係，在「舒適」的程度 内則繁衍、茁壯，而在「厭惡」的環境中則能促使老弱、 5敗亡。在本論中，另有更珍貴的發現，那就是：「環境的形 成，可因加入物質之性情、姿態、導向（物勢）而決定」； 譬如，正常的人體環境内，原「不適合」於癌細胞的生存、 活動，但當人體長期加入、感受、或承接了異常物質，因 它的性情、姿態、導向在體内變易了原有環境，才逐漸形 1〇成適合」於癌細胞的生存、活動，癌細胞於是繁衍、茁 壯，此乃罹癌的哲理。 值得慶幸的是，「藥物」也是一種「物質」，尤其是擁 有8仟品類以上的中草藥，自古傳記述，以及現代研析中 可知它鮮明的物勢，包括了質地、氣、味、成分等，也就 15是綜合性的藥理作用；只要瞭解癌環境的實況，再選擇適 當的藥物、慎重組合、再予以服食，當然可以藉藥物的性 情、姿態、導向、在癌患體内Γ形成」另一環境，變易為 々癌細胞難以「適應」，倍覺「厭惡」的環境，則繁衍、茁 壯受挫、老弱、敗亡增進，則癌症可治。 20 適宜於癌細胞生存、繁衍、茁壯的環境，已顯然的異 於正常人體内素質，稱為「癌的特殊體質」，經長期臨床、 研討而已能掌握它的病理現象，它就是癌的「周環病理」 論（參閱發明人著作權登記證書號2001_A-0342「廿一世紀 癌症治療新道路」第三章及附錄4 )。它是所有癌患體内必 1260226 10 15 20 發明說明續頁 然存在的’其固定性周環病理分別為⑴、騰腺功能低落， 與他器官之聯繫性不良，⑺、肝臟、門靜脈、脾臟内之 通透障礙，常呈現高壓病象，⑺、防f組織、淋巴循環 功能衰退、障礙。此三種病理所呈現的環境，就是「癌細 胞感覺舒適」的環境。 凡所有-切生物，皆由動能、空隙、實體、濕度、氣 流、溫度等六種要素所組成，是謂：「六大組成」論，人類 機體亦無例外（參閱附件二，發明人著作之「中醫藥之鎖與 鑰」、第一篇第五章），六大缺一即告死亡；在人體生理、 機能的六大之間，且存有—定限度的配合與運作，超越限 度者必然產生病態；癌症研究、治療的精微處，應該是切 實的瞭解癌環境中「六大要素」的變化與異常，並藉之採 取適宜治法，此即「六大要素之癌病理與論治」（參閱附件 二，發明人著作之「中醫藥之鎖與鑰」第二篇第七章）。 癌之分類形式頗多，有以癌之組織、結構、形態，或 以所在位置、系統而分類者；為了治療的施展與效益，發 明人乃深入探討各類癌種的關係，以及致病機理之同、異， 依據所得的「類型機理」而分為三大類型（見後）。癌之轉 移、擴散殊屬重要，它與化、放療後之關_深，但先前 甚 >、此種。己述、更乏疋論，·從此類型機理而可瞭解新創見 的「癌種轉移」論，可知所以轉移、擴散的原因，並經「癌 種動態統計」而得到證實。"Innovative Theory" The practice of the old "anti-cancer" theory can not break through the bottleneck and improve efficiency. It is the result of the invention that the inventor has created a new therapy that has become "easy to change the environment". Proving the expected high efficacy, 5 However, this therapy is derived from a new theory of inventor coherence, which is outlined for understanding and willingness to cherish. The new theory of coherence is in the following order: "The birth, the strong, the old, the death, the "material formation environment" theory, the "circumference pathology" theory of cancer, "the six major points: the pathology and treatment of cancer", And the "type of mechanism" in cancer, "carcinoma metastasis" 1 paradox, etc.; this new theory is inherent in the extension and creation of Chinese medical evidence," it is characterized by the integration of philosophy, the application of ancient China The philosopher Laozi and Li Wei (about 850 BC) wrote about the treatment of cancer based on natural physical phenomena and rules. Bai Xian, "The birth, strong, old, and dead" (see the inventor's copyright 15 registration certificate number 2〇〇1-Α·〇342 "廿-century cancer treatment new road", the second chapter of the previous paragraph), Explain that any object that can breed the same kind of descendants is "self-biological", which is called "biological" in modern times. The creatures cannot live forever." The normal ecology must have "born (reproduced), strong, The process of old and weak, sick and dead; "cancer cells" will also disappear in the body. 20 4 To achieve the above-mentioned hypothesis method, it is necessary to first understand the reality of cancer cells growing, strong, old, and dead. X is the process and cause of the disease environment, and then the "material formation environment" theory (Refer to the inventor's copyright to the New Zealand « calendar · Α _ 〇 342 "* - the new road to cancer treatment in the century" later in the second chapter). In this theory, it will be able to detect a common survival of living organisms - 6 - 1260226 _, invention description / continued page wow that is "the survival of living things, in its various categories, classes, families, genus, There is a certain degree of environmental adaptability. This degree of environmental adaptation is closely related to the birth, strength, old age and death of the material. It is proliferating and strong in the degree of "comfort", and in the "disgusting" environment. It can promote the old and weak, 5 defeat. In this theory, there is another more precious discovery: "The formation of the environment can be determined by the temperament, posture, and orientation (material) of the added material." For example, in the normal human environment, the original "not suitable" The survival and activity of cancer cells, but when the human body has long been added, felt, or taken over abnormal substances, because its temperament, posture, and orientation have changed the original environment in the body, it has gradually become suitable for cancer cells. Survival, activity, cancer cells are proliferating and strong, this is the philosophy of cancer. Fortunately, "drugs" are also a kind of "substance", especially Chinese herbal medicines with more than 8 categories, which are known from ancient times and modern research, including texture, gas, taste, composition, etc. 15 is a comprehensive pharmacological effect; as long as you understand the actual situation of the cancer environment, and then choose the appropriate drugs, careful combination, and then take it, of course, you can use the drug's temperament, posture, orientation, formation in cancer patients In another environment, it is easier for cancer cells to "adapt". If the environment is "disgusting", then the environment will be multiplied, frustrated, frail, old and weak, and the disease will be cured. 20 The environment suitable for cancer cells to survive, proliferate, and thrive is obviously different from the normal human body. It is called "special constitution of cancer." After long-term clinical and research, it can grasp its pathological phenomenon. It is cancer." Zhou Huan Pathology" (Refer to the inventor's Copyright Registration Certificate 2001_A-0342 "The Third Road of Cancer Treatment in the 21st Century" and Appendix 4). It is the body of all cancer patients must be 1260226 10 15 20 The invention continues to exist in the continuation of the 'the fixed perivascular pathology are (1), low dysfunction, poor association with his organs, (7), liver, portal vein, spleen Internal permeability barriers, often present with high-pressure disease, (7), anti-f tissue, lymphatic dysfunction, and obstacles. The environment presented by these three pathologies is the environment in which "the cancer cells feel comfortable." All-cut organisms are composed of six elements: kinetic energy, voids, solids, humidity, airflow, temperature, etc. It is said that the "six major components" theory, the human body is no exception (see Annex II, the inventor's work) "The lock and key of Chinese medicine", the first chapter of Chapter V), the death of the six major ones; between the six major physiology and function of the human body, and there is a limited cooperation and operation, beyond the limit It is inevitable that morbidity will occur; the subtleties of cancer research and treatment should be to understand the changes and abnormalities of the "six major factors" in the cancer environment, and take appropriate measures. This is the "six major factors of cancer pathology and treatment." (See Annex II, Chapter 2 of Chapter 2 of the Inventor's book "Locks and Keys of Traditional Chinese Medicine"). There are many types of cancer classification, such as cancer organization, structure, morphology, or classification by location and system; for the treatment and benefit of treatment, the inventors explored the relationship between various cancer types and the pathogenesis. The same, different, according to the "type mechanism" of the resulting three types (see later). The transfer and spread of cancer is very important. It is related to the treatment and post-radiation treatment. It is deep, but it is very early. It is said that there is a lack of paradox. From this type of mechanism, we can understand the theory of "cancer metastasis" of New Transcend, and we can see why the cause of metastasis and spread has been confirmed by "dynamic statistics of cancerous species".

治療分類」 -8- 1260226 _* 發明說明，續頁; 癌瘤是屬於上皮性的腫瘤，其主要的發生部位是皮膚 (顏面、頭及四肢等）；粘膜（口腔、食道、胃、腸、子宮 等）’腺體臟為（***、肝、腎、肺等）。並不原發於無上 皮性的骨、肌肉、結締組織及神經系統等處。依組織種類， 5匕可分為1 ·表皮癌或扁平細胞癌，2 ·單純性癌或腺細 胞癌或骰子形細胞癌或單純性充實性癌，3 ·腺癌或圓柱 細胞癌，4 ·膠樣癌及粘液癌。若依據臨床的性狀，又可 分為1 ·皮膚癌瘤，包括扁平皮膚癌、深蝕性癌、乳頭性 癌’多發生於顏面、頭、項、胸、臍、外陰、四肢等處。 10 2 ·粘膜之癌瘤，包括上皮性粘膜、圓柱上皮性粘膜，前 者多發生於***、口腔、上顎竇、食道、***、陰莖等處， 後者發生於胃、腸、及膽囊等處。3 .實質性臟器之癌瘤， 發生於***、肝、腎、胰、㈣、子宮、攝護腺、甲狀腺、 睪丸等處。 15 20Treatment classification" -8- 1260226 _* Description of the invention, continuation page; Cancer is an epithelial tumor, the main site of which is skin (face, head and limbs); mucous membrane (oral, esophagus, stomach, intestine, Uterus, etc.) 'Glandular organs are (breast, liver, kidney, lung, etc.). It is not originally found in epithelial bones, muscles, connective tissues, and nervous systems. According to the type of tissue, 5匕 can be divided into 1 · epidermal cancer or squamous cell carcinoma, 2 · simple cancer or adenocarcinoma or scorpion cell carcinoma or simple solid cancer, 3 · adenocarcinoma or cylindrical cell carcinoma, 4 · glue Carcinoid and mucinous cancer. According to clinical traits, it can be divided into 1 · skin cancer, including flat skin cancer, deep erosive cancer, papillary cancer, which occurs mostly in the face, head, item, chest, umbilicus, vulva, limbs, etc. 10 2 · Carcinoma of the mucosa, including epithelial mucosa and columnar epithelial mucosa, the former occurs mostly in the lips, mouth, upper sinus, esophagus, vagina, penis, etc., the latter occurs in the stomach, intestines, and gallbladder. 3. Cancer of a substantial organ, occurring in the breast, liver, kidney, pancreas, (four), uterus, prostate, thyroid, sputum, etc. 15 20

所有關係癌症的病理解剖、症候等等信息，均是癌 者所須知，然而’由於「抗癌」方針的存疑，以及原病 的短缺，加上療效低迷的事實，先前所有究竟未能盡為 據’而必要予以新的創革；例如i 9 5 〇年代的多數醫 教科書，對於肺癌的原發狀況謂：「#由肺泡上皮、支氣 上皮、支氣管腺上皮而特發者甚少」。且指肺癌多數系他 癌轉移而來，·㈣㈣人臨床所料，由肺⑽皮特發: 占多數’至於由肺轉移他處者，多數仍保留有肺癌的原; 症候。以本申請案1 7位肺癌患者計之，原發者有工1Λ 轉入而發者6人，原發肺癌再轉移肝、淋巴、骨者5人』 -9-All the information about the pathological anatomy and symptoms of cancer is what cancer patients need to know. However, due to the doubts about the "anti-cancer" policy, the shortage of the original disease, and the fact that the efficacy is low, all the previous failures have not been fulfilled. According to 'and necessary new creations; for example, most of the medical textbooks of the 1990s, the primary status of lung cancer: "# from the alveolar epithelium, stagnation epithelium, bronchial gland epithelium and very few special hair." It means that most of the lung cancer is caused by cancer metastasis. (4) (4) Clinically, the lung (10) skin hair: a majority 'as far as the lungs are transferred to other places, most still retain the original lung cancer; symptoms. According to the 17 patients with lung cancer in this application, the original person has 1 job and 6 persons, and the original lung cancer is transferred to the liver, lymph, and bone. 5-9

、 I 1260226 發明說明 保留有肺癌症候。 在癌症分類方面，本發明乃依各類型癌的特殊性情， 致病機理之同、異，各癌種之相互關係等等，即以癌之類 型機理而分類，此種分類的特徵，是在於治療用藥的直實 5性與效率；此乃有蓉於過去的治癌藥物，多概括於某系統 中，如某複方針對了消化系統的癌症，包括了食道、胃、 貪門、肝、胰、膽、腸等癌；但就發明人治癌經驗來說， 實覺有窒滯難行之處。 食道、胃、幽門、賁門屬於神經敏感的部位，當它發 10生癌瘤時，因過敏而必有唱,土、反食、上逆的反應，加上 癌腫粒的發炎現象而有阻塞、疼痛不堪的症候，類此緊迫 性病象若無法先予平伏，則藥物難以通過，癌藥不得發揮 作用，更何況此等癌腫粒另有特殊性情，豈能與肝、胰癌 同用一藥物？肝、胰雖是消化器官，但肝卻掌管了機體的 15化學、改毒重任，胰腺的内、外分泌亦是機體的重要司命； 且肝、胰癌多發生於臟器内部，具有特殊性情是所必然。 腸部亦系消化器官，但據發明人深入研究，它與腸淋巴總 結（培氏斑）、腸骨淋巴均有重大、密切關係，依據1950 年代之病理解剖證實··「原發性腸癌之種類，除少見肝門扁 20平上皮癌外，悉由Lieberkulms氏腺底之腺上皮、發生圓柱 性上皮癌；腺癌最多，髓樣癌、膠樣癌、硬性癌、依序次 之。」由此可知腸癌與淋巴腺的緊密關連性，且與上述二 種之治療分類難以混同。 綜合上述，是以依癌之類型機理，分成三類，1 ·是 1260226 發明說明續頁 為上消化迢敏感型，2 ·是肝、胰臟内本體型，3 ·是為 淋巴結關係型，亦即本申請之廣泛性癌類型；以此而分類， 將有利於用藥處治之施展與效率。 5 「類型機理」 癌症原發、或轉移於人體不同的器官、組織内，而有 各別的癌名；為了治療策略、用藥處治的方便與效益，必 須逐項研ό寸、探測其病機、病理，且以病機、病理之是否 雷同、密切關聯，而作為類型分判之依據，准此類型而分 10別配方用藥施治之，庶可方醫藥產品的利用、顧全療效的 確實與提升。 發明人乃准此原則，W彡癌瘤分為、「上消化道過敏 型」、「肝胰臟内本體型」、「淋巴結關係型」等三大類型； 本申請案之「廣泛性」、即指包括了較多癌種的「淋巴結關 15係型」。「淋巴結_型」的定義，是指此類型的所有癌種 別，均與淋巴結以及淋巴系統存在了直接、密切的關係； 為使理解，茲將本型之類型機理概述如下： 上腔及頭、頸項等處癌種別，與上顎竇、咽、舌、扁 桃體、頷下、頸、鎖骨、胸肺腺、腋下等淋巴結，發生密 20切關係，上述淋巴相距甚近，功能相互影響，故本處原ς 之癌平向、相互轉移的機率甚高；這些淋巴的循環，均^ 鎖月下靜脈角轉入血液循環裏，缺乏下向的***道，因 而上。卩癌在正常情況時，下移的機率較低。 下腹腔、腎、骨等訂部癌種別，均與乳糜池、腸骨、 1260226, I 1260226 Description of the invention Preserved lung cancer. In terms of cancer classification, the present invention is classified according to the specific temperament of each type of cancer, the same pathogenic mechanism, the relationship between cancer types, and the like, that is, the type of cancer is classified, and the classification is characterized by treatment. The straightness and efficiency of the medication; this is the past cancer treatment drug, more generalized in a system, such as a compound for the cancer of the digestive system, including the esophagus, stomach, greedy, liver, pancreas, Biliary, intestine and other cancers; but as far as the inventor's experience in cancer treatment is concerned, there is a real sense of stagnation. The esophagus, stomach, pylorus, and cardia are neurologically sensitive parts. When it produces 10 cancers, it must be sung because of allergies. The reaction of soil, anti-feeding, and anti-reverse, coupled with the inflammation of cancerous tumors, is blocked. If the symptoms of pain are unbearable, if the urgency of the disease is not able to be flattened first, the drug will be difficult to pass, and the cancer drug will not play a role. Moreover, these cancer granules have special temperament. Can you use a drug with liver and pancreatic cancer? Although the liver and pancreas are digestive organs, the liver is in charge of the body's 15 chemistry and poisoning. The internal and external secretion of the pancreas is also an important division of the body; and liver and pancreatic cancer often occur inside the organs, with special temperament. It is inevitable. The intestine is also a digestive organ, but according to in-depth study by the inventors, it has a significant and close relationship with the intestinal lymphatic summary (Pei's plaque) and the intestinal lymph, according to the pathological anatomy of the 1950s. · "Primary colon cancer The type, in addition to rare liver flat 20 epithelial cancer, known by the Lieberkulms glandular glandular epithelium, the occurrence of cylindrical epithelial cancer; adenocarcinoma most, medullary carcinoma, colloidal cancer, hard cancer, followed by. This makes it possible to understand the close relationship between intestinal cancer and lymph glands, and it is difficult to mix with the above two treatment classifications. In summary, according to the type mechanism of cancer, it is divided into three categories, 1 · is 1260226. The description of the invention is continued on the upper digestive sputum sensitive type, 2 · is the liver and pancreas inner body type, 3 · is the lymph node relationship type, That is, the broad type of cancer of the present application; classification by this will facilitate the administration and efficiency of medication treatment. 5 "Type Mechanism" Cancer is primary or transferred to different organs and tissues of the human body, and has individual cancer names. In order to treat the strategy and the convenience and benefit of medication treatment, it is necessary to study the pathology and detect the pathogenesis. , pathology, and whether the pathogenesis, pathology are similar, closely related, and as the basis for the type of sub-judgment, according to this type and divided into 10 different formula medications, the use of Qi Kefang pharmaceutical products, the actual effect of Upgrade. The inventor is in line with this principle. There are three types of W彡 carcinomas, such as “upper gastrointestinal allergy type”, “hepatic pancreatic body type”, and “lymph node relationship type”; This refers to the "lymph node off 15 series" that includes many cancer types. The definition of "lymph node_type" refers to all cancer types of this type, which have a direct and close relationship with lymph nodes and lymphatic system. For the sake of understanding, the type mechanism of this type is summarized as follows: upper cavity and head, The neck and other cancer types, and the upper sinus, pharynx, tongue, tonsil, underarm, neck, clavicle, chest lung gland, axillary and other lymph nodes, the relationship between the 20 secret, the above lymph nodes are very close, functional interaction, so this The rate of cancer in the plain and metastasis is very high; these lymphatic circulations are all transferred into the blood circulation in the lower venous angle, lacking the downward lymphatic duct, and thus on. Hepatocarcinoma is less likely to move down under normal conditions. Lower abdominal cavity, kidney, bone and other customized cancer types, both with chyle pool, intestinal bone, 1260226

B I 發明說明續頁 k氏斑、鼠蹊等淋巴結，以及鄰近淋巴系統發生㈣關係， 此等淋巴結相距甚近，功能直接影向，故原發本處之癌， 平向、相互轉移的機率亦高。但下腹腔内的器官附近，遍 佈了網狀微***，在逐漸集結後，匯合於乳糜池，即循 5 =巴導官而上升；在它注人鎖骨下主靜脈之先，癌細胞隨 #、木巴液上移接觸了淋巴結，當此淋巴結功能不能勝任 時就形成了下腔癌向上轉移的機理，因而下腔癌向上轉 移的機率特高，亦有轉移人肝臟者，則系經由Η靜脈所致。 癌之轉移機率，因上述原因而平移、同部轉移者多， 1〇下腔癌上移者多，唯有上腔癌下移之機率特低；但事實上 仍不乏有上焦癌種下移者，經過統計發覺，此異常現像是 化、放療所促進的；當上腔、頭、項、胸、乳部接受劇烈 性之化、、放療時，機體之器官、組織因系附著物而難逃酷 刑，=殘害性、遊擊性的癌細胞卻是狡兔三窟，自有選避 15舒，環境的天性，逢劇變發生則逃避到最遠程的下腹腔， 且多數選擇在缺乏***的臀、腿、腰脊骨内；此就是二、 放後多數下移的機理。 20The invention of BI describes the relationship between the lymph nodes of k-spots and squirrels, and the relationship between the adjacent lymphatic system (4). These lymph nodes are closely spaced and function directly, so the origin of the cancer is high, and the probability of horizontal and mutual transfer is also high. . However, near the organs in the lower abdomen, there are reticular micro-lymphatic vessels. After gradually gathering, they merge into the chyle pool, which rises according to the 5 = bar guide; before it injects the subclavian main vein, the cancer cells follow #,木巴液 Moves up to contact the lymph nodes. When this lymph node function is not competent, it forms a mechanism for the upward metastasis of the inferior vena cava. Therefore, the probability of upward metastasis of the lower cavity cancer is extremely high, and there is also a transfer of human liver. Caused by iliac veins. The rate of cancer metastasis, due to the above reasons, translation, the same part of the transfer, 1 〇 lower ventricular cancer upside, only the upper squamous cell carcinoma is particularly low; but in fact there is still no shortage of cancer Shifter, after statistical findings, this abnormality is promoted by chemotherapy and radiotherapy; when the upper cavity, head, item, chest, and breast are severely treated, and radiotherapy, the organs and tissues of the body are attached to the body. It is difficult to escape from torture. = The damaging and guerrilla cancer cells are the three caves of the Rex Rabbit. They choose to avoid the 15 Shu, the nature of the environment. When the drama changes, they escape to the most remote lower abdomen. Most of them choose the hips that lack lymphatic vessels. Legs, lumbar spine; this is the mechanism of the second, most of the downward movement after release. 20

、屋過統計而得下列綜結，Α·上焦（上腔與頭項部） 種向下轉移能度甚低’且低於本位之平轉、上移。Β上 癌經化、放療者’轉移能度增加3.5倍，向下轉移· 加⑷倍。C·下焦（下腹腔、腎、足部）癌在 療狀况下’向上轉移是上焦癌向下轉移的8倍，因下焦 移的高能度，故經化、放療後’轉上的; 罕乂〆參閱「癌種轉移統計」）。 -12- 1260226 ____ 發明說明，續頁 疫功能、延緩衰老，抗潰瘍的作用；在血液、造血功能、 心血管、抗腫瘤等方面，均有正面效用，可減輕肝之脂肪 變性，改善肝壞死，抑制肝淋巴間隙及中央靜脈下，膠原 纖維的形成。在本複方中，兼用以調和胰與各器官的聯繫。 5 黃芪一補充營養、微量元量、增強體力、增進淋巴導 管上升動能、調節自律神經、防止汗腺異常過敏。調節機 體水分代謝、利尿；改善淋巴體質、補充防禦細胞養分。 現代藥理研究證實，對免疫系統有良性影向，對機體代謝、 心血管系統有幫助；並有抗病毒、抗癌的作用。 10 薏苡仁一補充營養、健全胰腺功能，改善器官，尤其 是胰腺水分代謝障礙、清除肌肉、關節、韌膜内異常物質、 消炎、排膿。現代藥理實驗發現，有抑制骨胳肌改縮、降 血糖、解熱、抗炎、擴張肺血管等作用；顯著增加健康人 末梢血單核細胞產生抗體，增強體液免疫與抗腫瘤作用。 15 山佩蘭一安定胰、胃、脾功能，增強人體抵抗天氣暑 熱、耐能，發汗、解熱；促進局部組織水分代謝、與血液 循環，解除體内毒素。現代藥理實驗發現，具有抗宮頸鱗 癌的作用。本複方用以加強下腹腔内器官的通透性。 橘皮一調整胰、胃功能，緩和上消化道過敏，增進食 20 欲，袪除組織内稠粘物質，緩和氣管、支氣管過敏；因其 有稀釋稠粘物之功能，間接促進組織液、淋巴液的新陳代 謝以及器官的微循環。 二、排除門靜脈、肝、脾内的通透、障礙，平降門脈壓： 1260226發明說明續頁 爵床一調降體内偏高溫度，促進組織水分代謝； 15 20 肝内、、’田菌、微生物、排除肝内異質之障礙；幫助消化道駕 動、鎮痛、消炎。現代臨床研究發現、爵床有治療:廬疾 ***、結核性肛簍等效能。本複方用以調降門脈壓 並處理腸部的偏高溫度與淋巴循環。 夏括草—清除肝血竇、門脈管壁、脾腺的異質障礙、 通透肝循環、調降門脈壓。通透淋巴腺、消除其發炎、堪 硬病象。現代藥輯驗證實，有顯著的降血壓作用。臨房 研究、治療黃疸型肝炎、肺結核有效。 "7、物草—解除因天氣暑熱弓I起的人體不適與病候；補 充血液中陰柔元素、清除機體内激進成分，而有解毒、止 渴、清涼消炎的功效。可治療高血壓、糖尿病、民間用户 ^病感染的骨内疼痛。本複方用以平降門脈壓，改變癌環 境的偏高溫度，排除激進毒素。 、 振子-清除血液中激進元素，調降偏高溫度；促進 體水分代謝，清涼、利膽、解熱毒，平降門脈高壓， 肝膽，消除癌之發炎環境。 連翹-解熱、消炎、解毒、利尿、通透淋巴、消 =結的腫硬病象。現代藥理實驗，賴有廣效的抗微生物 乍用’有抗炎、抗肝損傷的效能，能強化末梢血管的強土 度’預防出血。本複方用作清涼降壓，改善變易的癌環境軔 广赤苟-解熱、平降血液溫度、排除血检、促進 ^現代樂理貫驗，有抗崎職，抗血小㈣集 脂和動脈硬化，抗腫瘤、保肝、改善血液循環的作用。The following statistics are obtained from the house statistics. The upper focus (upper cavity and head section) has a very low downward transferability and is lower than the standard. On the other hand, the degree of metastasis of cancer chemotherapy and radiotherapy increased by 3.5 times, and shifted downwards (4) times. C. Lower coke (lower abdominal cavity, kidney, foot) cancer under the condition of 'upward transfer is 8 times of the downward transfer of the upper coke cancer, due to the high energy of the lower focus shift, so after the chemotherapy, radiotherapy' turn; Rarely see "Cancer Transfer Statistics"). -12- 1260226 ____ Inventories, continuation of plague function, anti-aging, anti-ulcer effect; positive effects in blood, hematopoietic function, cardiovascular, anti-tumor, etc., can reduce liver steatosis, improve liver necrosis It inhibits the formation of collagen fibers in the lymphatic space of the liver and under the central vein. In this compound, it is also used to reconcile the relationship between the pancreas and various organs. 5 Astragalus supplemented with nutrients, trace amounts, increased physical strength, increased lymphatic vessel kinetic energy, regulation of autonomic nerves, and prevention of abnormal sweat glands. Regulates body water metabolism, diuresis; improves lymphatic quality and supplements defense cell nutrients. Modern pharmacological studies have confirmed that it has a benign influence on the immune system, which is helpful for the body's metabolism and cardiovascular system; and has antiviral and anticancer effects. 10 Coix seed adds nutrients, improves pancreatic function, improves organs, especially pancreatic water metabolism disorders, removes abnormalities in muscles, joints, and tough membranes, reduces inflammation, and discharges pus. Modern pharmacological experiments have found that it has the effects of inhibiting skeletal muscle remodeling, lowering blood sugar, antipyretic, anti-inflammatory, and dilating pulmonary blood vessels; it significantly increases the production of antibodies from peripheral blood mononuclear cells in healthy humans, and enhances humoral immunity and anti-tumor effects. 15 Mountain Perrin stabilizes the function of pancreas, stomach and spleen, enhances the body's resistance to weather heat, energy, sweating and antipyretic; promotes local tissue water metabolism, and blood circulation, and relieves toxins in the body. Modern pharmacological experiments have found that it has anti-cervical squamous cell carcinoma. This compound is used to enhance the permeability of organs in the lower abdomen. Orange peel adjusts pancreas and stomach function, alleviates allergic to upper digestive tract, promotes 20 desires, removes sticky substances in tissues, relieves tracheal and bronchial allergies, and indirectly promotes tissue fluid and lymph fluid because of its function of diluting sticky substances. Metabolism and microcirculation of organs. Second, the exclusion of portal vein, liver, spleen in the permeability, obstacles, flat descending portal pressure: 1260226 invention instructions continued to page the bed to reduce the body high temperature, promote tissue water metabolism; 15 20 liver,, 'field Bacteria, microorganisms, obstacles to exclude heterogeneity in the liver; help the digestive tract to drive, relieve pain, and reduce inflammation. Modern clinical research found that the treatment of the ceremonial bed: dysentery urinary tract infection, tuberculous anal fistula equivalent energy. This compound is used to reduce portal pressure and to treat the high temperature of the intestine and the lymphatic circulation. Xia Kucao - removes heterogeneous disorders of the hepatic sinus, portal vessel wall, and spleen gland, penetrates the liver circulation, and reduces portal pressure. It penetrates the lymph glands, eliminates inflammation and is a hard disease. The modern medicine series has a significant blood pressure lowering effect. It is effective to study and treat jaundice hepatitis and tuberculosis. "7, the grass - to relieve the discomfort and disease caused by the weather heat bow I; supplement the bloody feminine elements, remove the radical ingredients in the body, and have the effect of detoxification, thirst, cool and anti-inflammatory. It can treat intra-abdominal pain caused by hypertension, diabetes, and private users. This compound is used to lower the portal pressure, change the high temperature of the cancer environment, and eliminate aggressive toxins. , vibrator - removes radical elements in the blood, lowers the high temperature; promotes body water metabolism, cool, choleretic, antipyretic, flattening portal hypertension, hepatobiliary, eliminating the inflammatory environment of cancer. Forsythia - antipyretic, anti-inflammatory, detoxification, diuretic, clear lymphatic, eliminate the knot of swollen disease. Modern pharmacological experiments rely on a broad-spectrum anti-microbial use of 'anti-inflammatory, anti-liver damage efficacy, can strengthen the strong soil of peripheral blood vessels' to prevent bleeding. The compound is used as a cooling and blood pressure to improve the cancer environment of the change. The phlegm and blood stasis - antipyretic, flat blood temperature, blood test, promotion, modern music theory, anti-Kazaki, anti-blood (4) lipid collection and arteriosclerosis , anti-tumor, liver protection, improve blood circulation.

-16- 1260226 發明說明續頁 内水八 —夂十二指腸潰瘍；阻止結月 病毒：二:加快内容物排出而有導萬作用。有抗菌4 緩解門81作用。當其疏導、排出體时害物質時，^ 緩解門靜脈之高壓。 作用。旋血，解除血管中血栓，具有直接擴張血， 於微猶環中帶出敗…緩解栓；配合他葬 π出敗亡癌細胞或有害物質。 10 15-16- 1260226 Description of the invention Continued page Internal water eight - sputum duodenal ulcer; blocking the moon virus: two: speed up the discharge of content and have a guide effect. There is antibacterial 4 to relieve the effect of door 81. When it is contaminated and discharged, it relieves the high pressure of the portal vein. effect. Hemorrhage, relieve blood vessel thrombosis, has direct expansion of blood, in the micro-Jewish ring to bring defeat ... relieve the suppository; with him buried π out of cancer cells or harmful substances. 10 15

二、改，防禦功能、淋巴循環、提高免疫力： 主.：“舌草’月除激進元素引發的體内偏高溫度，解 :二促進局部組織’尤其是下腹腔内器官的體液代謝。現 代樂理試驗，有增強白細胞吞魏力，提高免疫力功能， 以及抗菌、抗腫瘤的作用。對於胃癌、直腸癌有—定療效。 扛板歸-促進機體水分代謝，利尿、消腫、解熱，排 除組織内血栓、毒素，民間用以治療性病感染之疾患，以 =腹水症。現代藥理實驗’發現有抗菌、抗病毒、抗腫 等作用。Second, change, defense function, lymphatic circulation, improve immunity: Main.: "The tongue grass" in addition to the high temperature in the body caused by radical elements, solution: two promote local tissue 'especially the body fluid metabolism of the lower abdominal cavity organs. Modern music theory test has the functions of enhancing white blood cell swallowing power, improving immunity function, and antibacterial and anti-tumor effects. It has a certain curative effect on gastric cancer and rectal cancer. 扛板归- promotes body water metabolism, diuresis, swelling, antipyretic, Exclusion of thrombus and toxins in tissues, and the use of folk diseases to treat sexually transmitted diseases, to ascites. Modern pharmacological experiments have found antibacterial, antiviral, anti-tumor effects.

山豆根-清除體内激進元素（退火），解毒、消咽喉炎 腫、鎮痛、殺蟲。現代藥理，本品所含多種生物碱，有抗 腫瘤作用。 、木槿皮-調降肺、大腸内部偏高溫度、稀釋組織中的 粘液f (逐飲）、抗菌、殺蟲。古方用以治療肺疽（肺腫瘤） 有定效果。現代藥理說明，從木槿皮中分得7種單體化 合物，其中的古柯三醇（erythr〇tri〇1)有抑制腫瘤細胞生 -17- 1260226 發明說明;續頁 長的作用。 天南星一祛除引發血管、微血管壓力異常的病因（祛 . 風），鎮靜、解痙、祛痰、淡化組織液稠粘度（逐飲）、通 透淋巴組織。現代藥理實驗證實，本品對人肺、肝、胃、 5 子呂荨癌’有直接殺傷或抑制作用。 半邊蓮一平降組織内偏高溫度，啟動防禦器官、促進 解毒功能（清熱解毒）。增進組織液代謝，消除腹水、足脛 腫脹（利水消腫）。通透器官内部微淋巴代謝、中和有毒元 素。現代藥理說明，有利尿、利膽汁、抗蛇毒等作用，可 鲁 10 治療肝硬化腹水、多種癌症。 白蔹一調降組織内偏高溫度，促進淋巴結及其它防禦 系統的解毒作用，緩解器官韌帶及結締組織的緊束狀態； 加速組織潰瘍的癒合。現代藥理實驗，說明有抗菌作用。 - 1992年李廣勤氏所述白斂之體外試驗，對人宮頸癌細胞培 15養系JTC_26有抑制作用，證明有抗癌效應。 漏蘆一促進血液循環，以及產婦乳汁分泌；降低機體 偏高溫度，增進防禦系解毒功能。現代藥理研究證明，有 抗動脈粥樣硬化、抗氧化、保肝、提高免疫功能等作用。 · 石葦-鬆弛攝護腺緊張’利尿；消除膀脱、尿道、攝 2〇護腺的發炎病象，治療膀胱、尿道出血。現代藥理研究， 對下腹腔内之多種菌體、病毒有抑制作用f其杧果甙 (mangiferin)有較強的抗單純鍈疹病毒的作用， 毒在細胞内複製。對於化學療法、放射線療法引起的白細 胞下降，有使其升高的作用；可增強機體吞嗟細胞能力。 -18- 1260226 發明說明_胃 乳香一促進血液、淋巴的正常循環，改善防禦器官功 能，配合他藥，排除血栓、癌細胞及其它異物。 沒藥一促進血液循環，排除循環内異質的障礙；以疏 通而達止痛效果。消除結締組織的異常腫脹。現代藥理研 5 究證實，有調降血脂、膽固醇、防止動脈壁斑塊形成的作 用。可抑制肝句漿膽固醇的形成。 四、通透淋巴結及其它必要作用： 蚤休一鎮靜神經，疏通淋巴器官及防禦組織，排除其 10 間異質。消除器官、組織、肝臟内的發炎、緊張病象。 敗醬一調降偏高溫度，增進防禦系統解毒功能；排除 血栓、膿液等體内異質。現代藥理證實，有鎮靜、抗菌、 抗病毒作用。高淑娟等氏在1992年「天津中醫」裏發表試 驗報告，謂可降低毒素活性，減毒倍數為8.7。 15 白芷一抗微生物、抗炎、解熱。袪除導致微血管壓力 異常的病因（祛風）；促進組織的水分代謝（利濕），消除 鼻咽腔粘膜炎腫、鎮痛，引導抗癌藥物致達胸腔、頭面部， 使他藥發揮治癌、改變癌環境的功能。 射幹一抗炎、解熱、稀釋稠粘痰液，清利咽喉炎痛， 20 消散淋巴結之結核。古籍記載，用本品可治療肝、胰腫硬 (瘧母、伏梁）。現代藥理，有抗炎、解熱、祛痰、抗菌、 抗流感病毒等作用。 蒲公英一促進淋巴組織内的通透性；排除機體内的有 毒物質，偏高溫度、發炎、腫脹。現代藥理說明，有抗病 -19- 1260226 發明說明續頁 原微生物、抗胃潰瘍、利膽、保肝等作用。並有動巨嗟 細胞、抗腫瘤的效能。 螺摩草-清除血液内激進成分，調降偏高體溫，增進 水分代謝功能，利尿，輔助防禦，解毒、殺蟲等功能。可 5通透胸肺部淋巴結，促進淋巴正常循環，加速治癌進度； 故舊醫藥典籍記載，有消除下腹腔内腫塊、沐巴結核 癌等作用。 皂莢-稀釋組織液及體内稠钻物、袪疫、緩解氣管、 支氣管内的痙攣、而有止咳作用；通利鼻腔、咽喉以及大 H)小便之不暢。解除水分代謝障礙引發的毒素（袪濕毒），殺 蟲、滅菌。現代藥理說明，有祛抗菌、溶血等作用。 獨活-排除引發血管、微血管壓力異常以及水分代謝 障礙的病因（風濕因子），調整體溫；鎮痛、解癌。現代藥 理實驗，有抗心律失常、延長血栓形成時間以及鎮痛、解 15痙、抗炎、抗菌的作用。所含吱喃香豆精類成分，具有抑 制P摻入HeLa細胞（人宮頸癌細胞）的作用；對艾氏腹水 癌細胞有殺滅作用。 麻肓一興奮中樞神經，增加神經、肌肉的傳遞功能， 俾使治癌藥物深入組織；是治療肺、淋巴、骨癌必要的藥 20 物。 升麻一增進淋巴導管上升動能，增加淋巴細胞活性， 誘導淋巴細胞產生幹擾素，在小腸淋巴結（培氏斑）等處， 以及胸腺以上淋巴結裏產生特殊的作用，故雖非抗癌藥 物，卻是治療腸部、肺部、頭頸部諸癌的重要藥物。 1260226 ^__ 發明說明_胃 NO: 2 中草藥名稱 黨 參學名 Codonopsis Pilosula Dangshen (Franch) Nannf 依 據 中藥大辭典第1837頁，中華本草第7冊第 607頁（中國上海科學技術出版社） 產地、採收季節、部位 山西、河南產。9〜10月挖出根部洗淨，曬 4〜6h，用小繩捆佳，揉搓使根充實，經反復 3〜4次處理，即可紮成小捆。 炮製、萃取過程、方法 (1) 4kg洗淨，切段入鍋水浸3h，加熱分二次 煎取藥液。 (2) 加熱揮發水分，至剩3公升膏液時，入茯 苓粉1kg攪勻。 (3) 65°C 乾燥。 (4) 粉碎過80目篩為末，密封收貯。 有 效成分 根中大部分含有果糖（fructose)，菊糖 (inulin)等多種糖類化合物；還含丁香甙 (syringin)等四種甙類；另含胆碱（choline),黑麥 草碱(perlolyrine)等生物碱及17種氨基酸。 另含蒲公英賽醇(taraxerol)等12種甾醇及 三莊成分；其它還有丁香醛 (syringaldehyde)等酸、S旨、酸類化合物以 及鐵、銅、銘、锰、鋅、鎳、銀、銘、叙、 氟等無機元素。 原記載藥理作用 增進胰腺、肺臟功能;補充營養，改善腺體 素質與分泌。現代藥理試驗，證明有增強機 體應激能力，免疫功能，有延緩衰老，抗潰瘍 等作用。對於血液、造血功能、心血管、 抗腫瘤等均有正面效用。減輕肝脂肪變. 改善肝壞死，抑制肝淋巴間隙及中央靜脈 下膠原纖維的形成。 藥理應用、目的 增進胰腺功能，改善腺體分泌與素質；調和 胰與各器官間的連系；補充柔和性營養、無 機元素。 -22- 1260226 厂__ 發明說明; NO: 4 中草藥名稱 薏贫仁 學名 Coix Lacyma-Jobi L. yiyiren 依 據 中藥大辭典第2645頁，中華本草第8冊第 329頁（中國上海科學技術出版社） 產地、採收季節、部位 福建、臺灣產。收取果實曬乾，脫殼、篩去 總苞和種皮。 炮製、萃取過程、方法 (1) 6kg洗淨，其1kg曬乾研為細末，另5kg 研為粗末，入鍋水浸3h，加熱以70°C為 限，連續6h，分三次泄下流浸液。 (2) 加熱揮發水分，至剩3公升時入薏苡仁 細末攪勻。 (3) 65°C 乾燥。 (4) 粉碎過120目篩為幼末收貯。 有 效成分 含蛋白質16.2%，脂肪4.65%，碳水化合物 79.17%，少量微生素B1，另含氨基酸薏苡素 (coixul)、薏苡醋（coixenolide)、三菇化合 物。 原記載藥理作用 健全胰腺功能，改善器官，尤其是胰腺水分 代謝障礙，清除肌肉，關節、韌膜内異常物 質，消炎、排膿。現代藥理實驗，有抑制骨胳 肌收縮、降血糖、解熱、抗炎、擴張肺血 管等作用。顯著增加健康人末梢血單核細 胞產生抗體，增強體力免疫與抗腫瘤的作 用。 藥理應用、目的 健全胰腺功能，改善器官水分代謝障礙，抗 炎、排膿。 1260226 發明說明ϋ胃 NO: 5 中草藥名稱 山佩蘭 學名Eupatorium shanpeilan japonicum thunb. 依 據 中華本草第7冊第838頁（中國上海科學技 術出版社） 產地、採收季節、部位 臺灣產。8、9月，割取地上部分，洗淨，鋪置 通風風處使半幹，再曬使全幹。本植物與中 藥大辭典1377頁記載之「佩蘭」不同；可 參閱中華本草第7冊、838頁。 炮製、萃取過程、方法 (1) 6kg洗淨，切段，其1kg曬乾研末；另5kg 入鋼水浸3h，加熱分二次煎取藥液。 (2) 加熱揮發水分，剩3公升時入藥末攪 勻。 (3) 45°C 乾燥。 (4) 粉碎、過120目篩為幼末收貯。 有 效成分 全草含已酸（hexanal)，2-己烯酸（2-hexenal) 龍腦（borneol)，桃金娘酸（myrtenal)，α -金合 歡稀（a -farnesene)等38種揮發油。又含大 槪牛兒烯（germacrene)D。葉含香豆精 (coumarin)，鄰一香研酸（O-coumaric acid)， 麝香草氫酿(thymohydroquinone)。又從葉 中分得白頭婆内酯（eupanin)，白頭婆素 (eupachifolin) A、B、C、D、E、華澤蘭素 (eupasimplicin) A、B及去乙統基華澤蘭素 A(或 B) [deacetyleupasimplicinA(or B)]。 原記載藥理作用 增強人體抵抗天氣暑熱能力，發汗、解熱； 安定胰、胃、脾功能，促進局部組織水分代 謝;促進血液循環，解除體内毒素。現代藥理 實驗，具有抗宮頸鱗癌的作用。 藥理應用、目的 安定胰、胃、脾的功能，促進血液、水分的 循環，加強下腹腔内器官的通透性。 - 25 - 1260226 發明說明_胃 NO: 7 中草藥名稱 爵床 學名 Rostellularia Juechuang procumbens(L.)Nees. 依 據 中藥大辭典第2682頁，中華本草第7冊第 472頁（中國上海科學技術出版社） 產地、採收季節、部位 福建、臺灣產。8〜9月盛花期採收，割取地 上部分、曬乾。 炮製、萃取過程、方法 (1) 6kg洗淨，切段，入锅水浸3h，加熱分二 次煎取藥液。 (2) 加熱揮發水分，剩3公升濃液時，入茯苓 粉1kg攪勻。 (3) 65°C 乾燥。 (4) 粉碎、過120目篩為幼末收貯。 有 效成分 含爵床脂定（justicidin)A，山荷葉素 (diphyllin)爵床脂定(justicidin)E，新爵床脂 素（neojusticin)A、B、C、D 原記載藥理作用 調降體内偏高溫度，促進組織水分代謝，殺 滅肝内細菌、微生物、排除肝内異質之障 礙；幫助消化道蠕動，鎮痛、消炎。現代臨床 研究、爵床有治療虐疾、***、結 核性肛瘻等效能。 藥理應用、目的 消炎、解毒，促進水分代謝，調降門脈壓。並 用以處理直腸、大腸的偏高溫度與淋巴循 環。 -27- 1260226 發明說明;_頁 NO: 10 中草藥名稱 振子學名 Gardenia jasminoides zhizi ellis 依 據 中藥大辭典第1984頁，中華本草第6冊 第421頁（中國上海科學技術出版社） 產地、採收季節、部位 福建、臺灣產。10月中、下旬，果皮由綠色 轉為黃綠色時採收。除去果柄、雜物，置蒸 籠中蒸熟，取出曬半幹，再烘乾，揉簸去果皮， 留種仁用。 炮製、萃取過程、方法 (1) 6kg，慢火炒透，研為粗末，入鍋浸於70 °C溫水中8h，分二次泄出藥液。 (2) 揮發水分，剩3公升濃液時，入茯苓粉 1kg攪勻。 (3) 65°C 乾燥。 (4) 粉碎過100目篩為細末收貯。 有 效成分 含振子甙（gardenoside)，都桷子甙 (geniposide),槐子酮武（gardoside)等 11 種 環稀醚菇類成分。又含綠原酸(chlorogenic acid)，藏紅花酸（crocetin)、藏紅花素 (crocin)等8種酸類成分。還含芸香武 (rutin)、膽碱(choline)等6種酮類成分。 原記載藥理作用 清除血液中激進元素，調降偏高溫，促進機 體水分代謝功能；具有清涼、利膽、解熱毒 的作用。 藥理應用、目的 促進機體水分代謝，清涼，利膽，解熱毒，以平 降門脈高壓，疏通肝循環，消除癌之發炎環 境。 -30- 1260226 「— _ 發明說明 NO: 11 中草藥名稱 連_ 學名 Forsythia suspensa Liangiao (thunb) vahl 依 據 中藥大辭典第1111頁，中華本草第6冊 第155頁（中國上海科學技術出版社） 產地、採收季節、部位 山西、河南產。10月上旬，果實熟透變黃， 果殼裂開時採收;曬乾、篩去種子及雜質。 炮製、萃取過程、方法 (1) 6kg洗淨，分裝入大型絹袋内，缚緊袋口， 入鍋，上壓以重物，水浸8h，分二次煎取 藥液。 P)加熱揮發水分，剩3公升時入茯苓粉 1kg攪勻。 (3) 65°C 乾燥。 (4) 粉碎過100目篩為末收貯。 有 效成分 含連麵武（forsythin，phillyrin)等3種木脂 體類化合物，芸香甙（rutin)以及連翹種甙 (suspensaside)等3種苯乙烧類衍生物，還含 連龜環已醇酮（rengyolone)等6種乙基環已 醇類衍生物。另含白樺脂酸(betulinic acid)， 齊墩果酸(oleanolic acid)，等6種三菇類化 合物。 原記載藥理作用 解熱、消炎，解毒、利尿，通透淋巴，消除淋 巴結的腫硬。現代藥理實驗，連翹有廣效的 抗微生物作用；有抗炎、抗肝損傷的效能； 能強化末梢血管的強韌度，預防出血。 藥理應用、目的 通透淋巴組織，改善變易的癌環境；特別用 於解熱、消炎、解毒，作為清涼降壓藥。 1260226 厂___：_ 發明說明續頁 NO: 12 中草藥名稱 赤芍 學名 Paeonia Veitchii chishao Lynch 依 據 中藥大辭典第1093頁，中華本草第3冊 第521頁（中國上海科學技術出版社） 產地、採收季節、部位 四川產。8-9月採挖，去除地上部分及泥土， 晾曬至半幹時，捆成小捆，再曬至全幹。 炮製、萃取過程、方法 (1) 川赤苟5kg洗淨、切片、入鋼水浸3h, 加熱分二次煎取藥液。 (2) 加熱揮發水分，剩3公升時入茯苓粉 1kg攪勻。 (3) 65t：乾燥。 (4) 粉碎過100目篩為末密封收貯。 有 效成分 川赤芍根含芍藥甙（Daeoniflorin),四川產 品還含微量的苯甲芍藥武（benzoyl paconiflorin) 〇 原記載藥理作用 促進血液循環，排除血栓，平降血液溫度，解 熱。現代藥理實驗，有抗血栓形成，抗血小板 聚集，降血脂和動脈硬化，抗腫瘤，保肝、改 善血液循環的作用。 藥理應用、目的 促進血液循環，通透下腹腔内器官的淋巴 組織;協同他藥，改善癌環境。Soybean root - removes radical elements (annealing), detoxification, sore throat, analgesia, and insecticide. Modern pharmacology, this product contains a variety of alkaloids, anti-tumor effect. , hibiscus - lowering the lungs, high temperature inside the large intestine, diluting the mucus in the tissue (by drinking), antibacterial, insecticidal. Ancient prescription for the treatment of pulmonary sputum (lung tumor) has a certain effect. Modern pharmacology shows that seven monomeric compounds are obtained from hibiscus, and that cocatriol (erythr〇tri〇1) inhibits the growth of tumor cells -17-1260226. In addition to the cause of abnormal blood vessels and microvascular pressure (祛. wind), Tiannan Xingyi calms, relieves phlegm, phlegm, dilutes the viscosity of tissue fluid (by drinking), and penetrates lymphoid tissue. Modern pharmacological experiments have confirmed that this product has direct killing or inhibition on human lung, liver, stomach and 5 荨 荨 cancer. The lobelia is flattened to a high temperature within the tissue, which activates the defensive organ and promotes detoxification (clearing and detoxifying). Improve tissue fluid metabolism, eliminate ascites, athlete's foot swelling (little water swelling). It penetrates the micro-lymphatic metabolism inside the organ and neutralizes the toxic elements. Modern pharmacological explanations, such as diuretic, bile, anti-venom, etc., can be used to treat cirrhosis ascites and various cancers. White peony reduces the high temperature in the tissue, promotes the detoxification of lymph nodes and other defense systems, relieves the tight state of the ligaments and connective tissues of the organs; accelerates the healing of tissue ulcers. Modern pharmacological experiments indicate an antibacterial effect. - In 1992, Li Guangqin's in vitro test of Baiyun's effect inhibited human cervical cancer cell line 15 JTC_26 and proved to have anticancer effect. Leaking a light promotes blood circulation, as well as maternal milk secretion; lowers the body's high temperature and enhances the detoxification function of the defense system. Modern pharmacological research has proved that it has anti-atherosclerosis, anti-oxidation, liver protection, and immune function enhancement. · Dendrobium - Relaxation of the prostate gland 'Diuretic; Eliminate the inflammatory pathology of the bladder, urethra, and sacral glands, and treat bladder and urethra bleeding. Modern pharmacological research has an inhibitory effect on a variety of bacteria and viruses in the lower abdomen. The mangiferin has a strong anti-pseudovirus effect, and the virus replicates in the cells. For the chemotherapy, radiation therapy caused by the decline of white blood cells, it has the effect of increasing it; it can enhance the body's ability to swallow cells. -18- 1260226 Description of the invention _ Stomach Frankincense promotes the normal circulation of blood and lymph, improves the function of defensive organs, and cooperates with other drugs to eliminate blood clots, cancer cells and other foreign bodies. Myrrh-promoting blood circulation, eliminating the disorder of heterogeneity in the circulation; to relieve pain by dredging. Eliminate abnormal swelling of connective tissue. Modern pharmacology research 5 confirmed that it has the effect of lowering blood fat, cholesterol, and preventing the formation of plaque on the arterial wall. It can inhibit the formation of cholesterol in the liver. Fourth, transparent lymph nodes and other necessary effects: 蚤 一 a calm nerve, dredge lymphoid organs and defense tissue, exclude 10 heterogeneity. Eliminate inflammation, nervousness in organs, tissues, and liver. The degraded sauce is lowered to a high temperature to enhance the detoxification function of the defense system; the thrombosis, pus and other in vivo heterogeneity are excluded. Modern pharmacology has confirmed that it has sedative, antibacterial and antiviral effects. Gao Shujuan et al. published a test report in the “Tianjin Traditional Chinese Medicine” in 1992, which said that the activity of toxins can be reduced, and the attenuation ratio is 8.7. 15 White peony is an anti-microbial, anti-inflammatory, antipyretic. Eliminate the cause of abnormal microvascular pressure (hurricane); promote tissue water metabolism (librosis), eliminate mucosal inflammation and analgesia of nasopharyngeal cavity, guide anticancer drugs to reach the chest, head and face, so that other drugs can play a role in cancer treatment Change the function of the cancer environment. Shoot dry anti-inflammatory, antipyretic, dilute thick sputum, clear throat and sore throat, 20 dissipate tuberculosis of lymph nodes. According to ancient books, this product can be used to treat liver and pancreas (malaria, Fuliang). Modern pharmacology, anti-inflammatory, antipyretic, expectorant, antibacterial, anti-influenza virus and so on. Dandelion promotes permeability in lymphoid tissues; removes toxic substances from the body, which is high in temperature, inflammation, and swelling. Modern pharmacological explanation, there is resistance to disease -19- 1260226 Description of the invention Continued page The original microorganism, anti-gastric ulcer, choleretic, liver protection and other effects. It also has the effect of moving giant cells and anti-tumor. Spiral Mosquito - removes the radical components of the blood, lowers the body temperature, enhances the function of water metabolism, diuretic, auxiliary defense, detoxification, insecticidal and other functions. It can penetrate the lymph nodes of the chest and lungs, promote the normal circulation of lymphatics, and accelerate the progress of cancer treatment. Therefore, the old medical classics record that it can eliminate the lower abdominal cavity mass and muba tuberculosis cancer. Acacia - diluted tissue fluid and thick diamonds in the body, plague, relieve trachea, bronchospasm, and have a cough effect; Tongli nasal cavity, throat and large H) urinary dysfunction. Relieve toxins (sweet and poison) caused by water metabolism disorders, killing insects and sterilizing. Modern pharmacological explanations have the effects of antibacterial and hemolysis. Living alone - to rule out the cause of blood vessels, microvascular pressure abnormalities and water metabolism disorders (rheumatoid factor), adjust body temperature; analgesia, cancer. Modern pharmacological experiments have anti-arrhythmia, prolonged thrombosis time, and analgesic, anti-inflammatory, antibacterial effects. It contains a component of scented coumarin, which has the effect of inhibiting the incorporation of P into HeLa cells (human cervical cancer cells); it has a killing effect on Ehrlich ascites cancer cells. Paralysis excites the central nervous system, increases the function of nerves and muscles, and makes cancer treatment drugs deep into tissues; it is a necessary medicine for treating lung, lymph and bone cancer. Cimicifuga increases lymphatic vessel kinetic energy, increases lymphocyte activity, induces lymphocyte production of interferon, and has a special effect in small intestinal lymph nodes (Pei's plaque) and lymph nodes above the thymus, so although it is not an anticancer drug, It is an important drug for the treatment of cancers in the intestines, lungs, head and neck. 1260226 ^__ Description of invention _ stomach NO: 2 Chinese herbal medicine name Codonopsis Pilosula Dangshen (Franch) Nannf According to the Chinese Medicine Dictionary 1837, Chinese Materia Medica No. 7 (page 607 (Shanghai Science and Technology Press, China) Origin, harvest season , Shanxi, Henan. 9~10 months, the roots are washed and dried for 4~6h. They are bundled with small ropes, and the roots are enriched. After repeated 3~4 treatments, they can be bundled into small bundles. Processing, extraction process, method (1) Wash 4kg, cut into the pot and immerse for 3h, and heat to separate the liquid. (2) Heat the volatile water, and when it is 3 liters of the remaining solution, add 1 kg of 茯 powder and mix well. (3) Dry at 65 °C. (4) Smash the 80 mesh sieve to the end, seal and store. Most of the active ingredient roots contain fructose, inulin and other sugar compounds; they also contain four kinds of sugars such as syringin; and other choline, lyophilized, etc. Alkaloids and 17 amino acids. It also contains 12 kinds of sterols and trizans such as taraxerol; other acids such as syringaldehyde, S, acid compounds and iron, copper, Ming, manganese, zinc, nickel, silver, Ming, Inorganic elements such as sulphur and fluorine. Originally recorded pharmacological effects to improve pancreas and lung function; supplement nutrition, improve gland quality and secretion. Modern pharmacological tests have proven to enhance the body's ability to stress, immune function, delay aging, and anti-ulcer. It has positive effects on blood, hematopoietic function, cardiovascular and anti-tumor. Reduce liver fat. Improve liver necrosis, inhibit the formation of collagen fibers in the hepatic lymphatic space and central vein. Pharmacological application, purpose To improve pancreatic function, improve gland secretion and quality; reconcile the connection between pancreas and various organs; supplement soft nutrition, inorganic elements. -22- 1260226 Factory __ Invention Description; NO: 4 Chinese herbal medicine name 薏 poor ren scientific name Coix Lacyma-Jobi L. yiyiren According to the Chinese Medicine Dictionary 2645, Chinese Materia Medica No. 8 (page 329 (Shanghai Science and Technology Press, China) Origin, harvest season, location Fujian, Taiwan. The fruit is dried, shelled, and sieved to the total sorghum and seed coat. Processing, extraction process, method (1) 6kg washing, 1kg dry research into fine, another 5kg research into coarse, water immersed for 3h, heating is limited to 70 °C, continuous 6h, three times drain immersion liquid. (2) Heat the volatile water, and mix it into the hazelnuts when it is 3 liters. (3) Dry at 65 °C. (4) Smashed through a 120 mesh sieve for storage at a young age. The active ingredient contains 16.2% protein, 4.65% fat, 79.17% carbohydrate, a small amount of vitamin B1, and contains amino acid coixul, coixenolide and three mushroom compounds. Originally recorded pharmacological effects Improve pancreatic function, improve organs, especially pancreatic water metabolism disorders, remove abnormalities in muscles, joints, and tough membranes, anti-inflammatory, and discharge pus. Modern pharmacological experiments have the effects of inhibiting skeletal muscle contraction, lowering blood sugar, antipyretic, anti-inflammatory, and dilating pulmonary blood vessels. Significantly increase the production of antibodies to peripheral blood mononuclear cells in healthy humans, enhancing physical immunity and anti-tumor effects. Pharmacological application, purpose To improve pancreatic function, improve organ water metabolism disorder, anti-inflammatory, discharge pus. 1260226 Description of the invention ϋ stomach NO: 5 Chinese herbal medicine name Mountain Perrin Scientific name Eupatorium shanpeilan japonicum thunb. According to Chinese herbal medicine No. 7 (page 838 (China Shanghai Science and Technology Press) Origin, harvest season, parts Taiwan. In August and September, cut off the ground part, wash it, lay it in the ventilation air to make it semi-dry, and then let it dry. This plant is different from the "Peland" described on page 1377 of the Chinese Dictionary of Traditional Chinese Medicine; please refer to Book 7, 838 of Chinese Materia Medica. Processing, extraction process, method (1) 6kg washed, cut into sections, 1kg dried in the ground; another 5kg into the steel for 3h, heated to separate the liquid. (2) Heat the volatile water and mix it with the remaining 3 liters. (3) Dry at 45 °C. (4) Crushing and passing through a 120 mesh sieve for storage at the end of the baby. Effective ingredients The whole plant contains 38 kinds of volatile oils such as hexanal, 2-hexenal, borneol, myrtenal and α-farnesene. It also contains large germacene D. The leaves contain coumarin, O-coumaric acid, and thymohydroquinone. Also obtained from the leaves are eupanin, eupachifolin A, B, C, D, E, eupasimplicin A, B and sulphate valerin A (or B) [deacetyleupasimplicinA(or B)]. Originally recorded pharmacological effects to enhance the body's ability to resist weather heat, sweating, antipyretic; calm pancreas, stomach, spleen function, promote local tissue water metabolism; promote blood circulation, remove toxins from the body. Modern pharmacological experiments have the effect of resisting cervical squamous cell carcinoma. Pharmacological application, purpose The function of stable pancreas, stomach and spleen promotes the circulation of blood and water and strengthens the permeability of organs in the lower abdomen. - 25 - 1260226 Description of invention _ Stomach NO: 7 Chinese herbal medicine name The name of the Chinese medicine Rostellularia Juechuang procumbens (L.) Nees. According to the Chinese Dictionary of Chinese Medicine, page 2682, Chinese Materia Medica No. 7 (page 472 (Shanghai Science and Technology Press, China) Harvest season, location Fujian, Taiwan production. It is harvested during the flowering period from August to September, and the ground part is cut and dried. Processing, extraction process, method (1) 6kg washed, cut into sections, immersed in the pot for 3h, and heated to take the liquid twice. (2) Heat the volatile water. When 3 liters of concentrated solution is left, mix 1 kg of mash powder and mix well. (3) Dry at 65 °C. (4) Crushing and passing through a 120 mesh sieve for storage at the end of the baby. The active ingredient contains justicidin A, diphyllin, justicidin E, neojusticin A, B, C, D. High temperature, promote tissue water metabolism, kill liver bacteria, microorganisms, remove obstacles in liver heterogeneity; help digestive tract peristalsis, analgesia, anti-inflammatory. Modern clinical research, Jue bed has the equivalent of treating malaria, urinary tract infection, and nucleus anal fistula. Pharmacological application, purpose Anti-inflammatory, detoxification, promote water metabolism, reduce portal pressure. It is also used to treat the high temperature of the rectum and large intestine and the lymphatic circulation. -27- 1260226 Description of invention; _ page NO: 10 Chinese herbal medicine name Zhenzi scientific name Gardenia jasminoides zhizi ellis According to the Chinese Medicine Dictionary 1984, Chinese Materia Medica No. 6 (page 421 (Shanghai Science and Technology Press, China) Origin, harvest season, The location is made in Fujian and Taiwan. In the middle and late October, the peel was harvested from green to yellowish green. Remove the handle and debris, steam in the steaming cage, remove the sun and dry, then dry, peel off the peel, and keep the seed. Processing, extraction process, method (1) 6kg, slow fire fry, research into coarse, immersed in 70 °C warm water for 8h, the second discharge of liquid. (2) Volatile water, when 3 liters of concentrated solution is left, mix 1 kg of glutinous powder and mix well. (3) Dry at 65 °C. (4) Smashed through a 100 mesh sieve for fine storage. Effective ingredients include gardenoside, geniposide, gardoside and other 11 kinds of ring-like ethers. It also contains eight kinds of acid components such as chlorogenic acid, crocetin and crocin. It also contains six ketone components such as rutin and choline. Originally recorded pharmacological effects to remove radical elements in the blood, reduce the high temperature, promote the body's water metabolism; have a cool, choleretic, antipyretic effect. Pharmacological application, purpose To promote the body's water metabolism, cool, choleretic, antipyretic, to lower the portal hypertension, dredge the liver circulation, eliminate the inflammatory environment of cancer. -30- 1260226 ― _ Invention Description NO: 11 Chinese herbal medicine name _ scientific name Forsythia suspensa Liangiao (thunb) vahl According to the Chinese Medicine Dictionary 1111, Chinese Materia Medica No. 6 (page 155 (Shanghai Science and Technology Press, China) Origin, In the harvest season, the parts are produced in Shanxi and Henan. In early October, the fruit is ripe and yellow, and the shell is harvested when it is cracked; dried and sieved to remove seeds and impurities. Processing, extraction process and method (1) 6kg washing, Dispense into a large bag, tie the bag mouth, put into the pot, press on the heavy object, soak for 8h, and take the liquid twice. P) Heat the volatile water, add 3kg into the powder after mixing 3 liters. (3) Dry at 65 ° C. (4) Smashed 100 mesh sieve for final storage. The active ingredients include three kinds of lignan compounds such as forsythin, phillyrin, rutin and forsythia Three kinds of acetophenone derivatives such as suspensaside, including 6 kinds of ethylcyclohexanol derivatives such as rengyolone, and betulinic acid, olean Acid (oleanolic acid), and other six kinds of three mushroom compounds. Antipyretic, anti-inflammatory, detoxification, diuretic, clear lymph, eliminate the swelling of lymph nodes. Modern pharmacological experiments, forsythia has a broad-spectrum anti-microbial effect; anti-inflammatory, anti-liver damage efficacy; can strengthen the toughness of peripheral blood vessels, Prevent bleeding. Pharmacological application, purpose to penetrate lymphoid tissue, improve the cancer environment; especially for antipyretic, anti-inflammatory, detoxification, as a cooling antihypertensive drug. 1260226 Factory ___:_ Invention Description Continued NO: 12 Chinese herbal medicine name Akasaka The scientific name Paeonia Veitchii chishao Lynch is based on the Chinese Medicine Dictionary No. 1093, Chinese Materia Medica No. 3, page 521 (Shanghai Science and Technology Press, China). Origin, harvest season, and location in Sichuan. Mining from August to September, removing the aboveground parts and Soil, when drying to a semi-dry, bundle into small bundles, and then dry until dry. Processing, extraction process, method (1) 5kg of Chuan Chisong, washed, sliced, infused with steel for 3h, heated to sub-fresh (2) Heat the volatile water, and mix it with 1kg of glutinous powder when 3 liters is left. (3) 65t: dry. (4) Smashed 100 mesh sieve to seal the end. The active ingredient Chuanchi 芍 root contains 芍Daeoniflorin, Sichuan products also contain trace amounts of benzoyl paconiflorin. Pharmacopoeia records pharmacological effects to promote blood circulation, eliminate blood clots, lower blood temperature, and resolve heat. Modern pharmacological experiments, antithrombotic, antiplatelet aggregation , lowering blood fat and arteriosclerosis, anti-tumor, liver protection, improve blood circulation. Pharmacological application, purpose To promote blood circulation, penetrate the lymphoid tissue of the lower abdominal organs; cooperate with other drugs to improve the cancer environment.

-32- 1260226 . 發明說明$賣頁 NO: 16 中草藥名稱 扛板歸 學名Polygonum per Gangbangui foliatum L. 依 據 中藥大辭典第869頁，中華本草第2冊第 685頁（中國上海科學技術出版社） 產地、採收季節、部位 福建、臺灣產。夏秋季撥取全草及根莖， 洗淨，切段、暗乾。 炮製、萃取過程、方法 (1) 6kg洗淨，入鋼水浸8h，加熱分二次煎取 藥液。 (2) 加熱揮發水分，剩3公升時入茯苓粉 1kg攪勻。 (3) 65°C 乾燥。 (4) 粉碎過120目篩為幼末收貯。 有 效成分 全草含山柰紛(kaempferol)，咖啡酸曱醋(caffeic acid methyl ester)，槲皮素（quercetin)，咖啡酸 (caffeic acid)，原兒茶酸(protocate chuic acid)，槲皮 素-3- /3 -D_葡萄糖酿酸甲S旨（quercetin-3- /3 -D-glucuronide methylester)，對香豆酸(P-coumaric acid)，阿魏酸(ferulic acid)，香草酸(Vanillicacid)，熊 果酸(ursolic acid)，白樺脂酸(betulic acid),白樺脂 醇(betulin)，還含有甾醇脂肪酸脂，植物甾醇/3 -D-葡萄糖武(Phytosteryl- /5 -D-glucoside)，3,3’，4,4’-四曱基並沒食子酸(3,3’，4,4’-tetramethylellagic acid)，3,3’二甲基並沒食子酸(3,3’-dimethylellgic acid)，内消旋灑石酸二甲酯（dimethyl mesotartrate)及長鏈脂肪酸酯。另外還含有散武 (indican)和鞣質。根及根莖另含少量大黃素 (e-modin)^i 大黃紛(chrysophand) 〇 原記載藥理作用 促進機體水分代謝，利尿，消腫，解熱；排除 組織内血栓、毒素，民間用以治療淋病感染 及性病疾患，以及腹水症。現代藥理實驗， 有抗菌、抗病毒、抗腫瘤等作用。 藥理應用、目的 協同他藥增強抗菌、抗病毒、抗腫瘤效能， 並稟其促進水分代謝藥理，迅速把有害素 質排出體外。 -36- 1260226 發明說明，續頁 NO: 17 中草藥名稱 山豆根 學名 Sophora tonkinensis Shandougen Gagnep 依 據 中藥大辭典第181頁，中華本草第4冊第 652頁（中國上海科學技術出版社） 產地、採收季節、部位 廣西產，秋季採收根部，除去雜質，洗淨，B麗 乾。 炮製、萃取過程、方法 (1) 5KG洗淨,浸切，1KG烘乾研末，另4KG 入鍋水浸8H，加熱分二次煎取藥液。 (2) 加熱揮發水分，剩3公升時入原藥末攪 勻。 (3) 65°C 乾燥。 (4) 粉碎過120目篩為細末收貯。 有 效成分 含苦參碱（matrine)，氧彳匕苦參碱 (oxymatrine)，臭豆碱（Anagyrine)和曱基金 雀花碱(methylcytisine)等生物碱。各類黃 酮成分，柔枝槐酮（sophoranone)柔枝槐素 (sophoradin)， 柔枝槐 8¾ 色烯 (sophoranochromene)，柔枝槐素色烯 (sophoradochromene)，染色木素（genistein)， 紫檀素（pterocarpine)，山槐素（maackian)，紅 車軸草根武（trifolirhizin)，穀留醇，蛇麻脂 醇，一群咖啡酸的高級烷醇酯以及一種未 定的青色螢光物 原記載藥理作用 清除體内激進元素（退火），中和有毒元素 (解毒）;消咽喉發炎、腫脹，鎮痛、殺蟲。現 代藥理，本品含有的多種生物碱有抗腫瘤 作用。 藥理應用、目的 清除體内激進元素，中和有毒元素，減輕防 禦系統的負擔。-32- 1260226 . Description of the invention $ Selling page NO: 16 Chinese herbal medicine name 扛 归 Po Polygonum per Gangbangui foliatum L. According to the Chinese Medicine Dictionary 869, Chinese Materia Medica Volume 2, page 685 (Shanghai Science and Technology Press, China) Harvest season, location Fujian, Taiwan production. In the summer and autumn, the whole grass and roots are taken, washed, cut into sections, and dried. Processing, extraction process, method (1) Wash 6kg, dip in steel for 8h, and heat twice to extract the liquid. (2) Heat the volatile water, and add 3 kg of glutinous powder to the remaining 3 liters. (3) Dry at 65 °C. (4) Smashed through a 120 mesh sieve for storage at a young age. The active ingredient whole grass contains kaempferol, caffeic acid methyl ester, quercetin, caffeic acid, protocate chuic acid, quercetin- 3- /3 -D_glucose acid S ( quercetin-3- /3 -D-glucuronide methylester), p-coumaric acid, ferulic acid, vanillic acid (Vanillicacid ), ursolic acid, betulic acid, betulin, also contains sterol fatty acid lipids, phytosteryl- /5 -D-glucoside ,3,3',4,4'-tetradecyl-3,3',4,4'-tetramethylellagic acid, 3,3'-dimethyl-gallate acid (3,3 '-dimethylellgic acid), dimethyl mesotartrate and long chain fatty acid esters. It also contains indican and tannins. Roots and rhizomes additionally contain a small amount of emodin (e-modin) ^i rheas (chrysophand) 〇原 records pharmacological effects to promote the body's water metabolism, diuretic, swelling, antipyretic; exclude tissue thrombosis, toxins, folk treatment Gonorrhea infection and sexually transmitted diseases, as well as ascites. Modern pharmacological experiments have antibacterial, antiviral and antitumor effects. Pharmacological application, purpose Synergistic with other drugs to enhance antibacterial, antiviral, anti-tumor efficacy, and promote its water metabolism pharmacology, and quickly remove harmful substances. -36- 1260226 Inventive Note, Continued NO: 17 Chinese herbal medicine name Sophora tonkinensis Shandougen Gagnep According to the Chinese Medicine Dictionary, page 181, Chinese Materia Medica Volume 4, page 652 (Shanghai Science and Technology Press, China) Origin, harvest The seasons and parts are produced in Guangxi, and the roots are harvested in the autumn to remove impurities, washed, and dried. Processing, extraction process, method (1) 5KG washing, dip-cutting, 1KG drying and grinding, and another 4KG is immersed in water for 8H, and heating is used to take the liquid twice. (2) Heat the volatile water, and mix it with the original drug at the end of 3 liters. (3) Dry at 65 °C. (4) The 120 mesh sieve is pulverized for fine storage. Effective ingredients include matrine, oxymatrine, Anagyrine and alkaloids such as methylcytisine. Various flavonoids, sophoranone sophoradin, sophoranochromene, sophoradochromene, genistein, rosewood Pterocarpine), maackian, trifolirhizin, linalol, hop alcohol, a group of higher alkanol esters of caffeic acid, and an undetermined cyan fluorescein documented pharmacological action to remove the body Radical elements (annealing), neutralizing toxic elements (detoxification); eliminating throat inflammation, swelling, analgesia, insecticide. Modern pharmacology, this product contains a variety of alkaloids that have anti-tumor effects. Pharmacological application, purpose To remove radical elements in the body, neutralize toxic elements, and reduce the burden of the defense system.

-37- 1260226 厂__ 發明說明 NO: 18 中草藥名稱 木槿皮 學名 Hibiscus syriacus L. Mujinpi 依 據 中藥大辭典第366頁，中華本草第5冊第 357頁（中國上海科學技術出版社） 產地、採收季節、部位 臺灣產。4、5月，割取地上部分，削去花、 葉、幼枝，留尾指大小以上莖，重器捶破硬 骨，取皮，切段曬乾。 炮製、萃取過程、方法 (1) 5kg洗淨，入锅水浸8h，加熱分二次煎取 藥液。 (2) 加熱揮發水分，剩3公升時入茯苓粉 1kg攪勻。 (3) 45°C 乾燥。 (4) 粉碎過120目篩為幼末收貯。 有 效成分 含辛二酸（suberic acid)，l-二十八醇 (Ι-octacosand)，冷-穀甾醇（/5 -sitosterol)，l，22-二十二碳二醇（1，22 docosanediol)，白樺脂醇（betulin)，古柯三醇 (erythrotriol)，壬二酸（nonanedioic acid);又 含脂肪酸包括肉豆蔻酸(myristic acid),棕 橺酸(palmitic acid),月桂酸（lauric acid)，另 含鐵屎米酮（canthin-6-one)。 原記載藥理作用 調降肺、大腸部偏高溫度，稀釋組織中的稠 粘度（逐飲），抗菌、殺蟲。右方用以治療肺 疽（肺腫瘤）有效。現代藥理說明，從木槿皮 中分得7種單體化合物，其中的古柯三醇 (erythrotriol)有和卩制腫瘤細胞生長的作用。 藥理應用、目的 調降肺、大腸組織内偏高溫度，稀釋淋巴組 織中的稠粘度，以改善防禦功能。信任古籍 治療肺腫瘤經驗以及現代藥理說明，直接 作用於肺、腸等部癌細胞，配合他藥，改善體 内環境。 -38- 1260226 發明說明; NO: 19 中草藥名稱 天南星 學名Arisaema Tiannanxing heterophyllum B1 依 據 中藥大辭典第329頁，中華本草第8冊第 504頁（中國上海科學技術出版社） 產地、採收季節、部位 江西產。10月挖出塊莖，去掉泥土及莖、 葉、鬚根，裝入撞兜（木桶型制藥用具）内撞 搓，撞去表皮，倒出洗淨，再用竹刀刮淨表皮， 最後用硫黃燻制，使其色白，曬乾。 炮製、萃取過程、方法 (1) 取粒體大小接近天南星3KG，水漂浸，每 曰換水2〜3次，候起白沫時再換水，並加 入白礬120mg，泡浸1日後再換水，至切 開口嘗微有麻舌感時取出。 (2) 取泡過天南星加生薑片1KG煮4H，取出 晾至8成幹，切片，曬乾。 (3) 取1KG研末，另2KG入鍋水浸3H，加熱 分二次煎取藥液。 (4) 揮發水分，剩2.5KG時入原藥末攪勻。 (5) 65°C 乾燥。 (6) 粉碎過120目篩為幼末收貯。 有 效成分 含L-脯氨酸-L-綠氨酸酐（L-prolyl-L-valine anhydride)，脲嘴σ定(uracil)，胸腺鳴σ定(thymine)，煙 酸胺(nicotinamide)等多生物碱和環二肽類化合 物成分以及掌葉半夏碱(pedatisectine)A、B、C、 D、E。還含胡蘿蔔甙(daucosterol)，/3 -穀甾醇(/3 -stitosterol)，標摘酸(palmitic acid)以及脯氨酸 (proline)等30多種氨基酸和20多種無機微量元 素。 原記載藥理作用 祛除引發血管、微血管壓力異常的病因,鎮靜、 解痙;祛痰、淡化組織液稠钻度，通透淋巴組織。 現代藥理實驗，本品對人肺、肝、胃、子宮等癌， 有直接殺傷或抑制作用。 藥理應用、目的 調整微血管的正常壓力，淡化組織液稠粘 度，通透淋巴組織，協同他藥，改善變易的癌 環境。 39--37- 1260226 Factory__ Invention Description NO: 18 Chinese herbal medicine name Muqipi Hibiscus syriacus L. Mujinpi According to Chinese Medicine Dictionary No. 366, Chinese Materia Medica Volume 5, page 357 (Shanghai Science and Technology Press, China) Origin, harvest Seasons and parts are produced in Taiwan. In April and May, cut the ground part, cut off the flowers, leaves, and young branches, leaving the stems above the size of the tail fingers, smashing the hard bones, taking the skin, and cutting the sections to dry. Processing, extraction process, method (1) Wash 5kg, immerse in a pot for 8h, and heat to separate the liquid. (2) Heat the volatile water, and add 3 kg of glutinous powder to the remaining 3 liters. (3) Dry at 45 °C. (4) Smashed through a 120 mesh sieve for storage at a young age. The active ingredient contains suberic acid, l-octacosto, cold-sitosterol, 1,22-docosenediol (1,22 docosanediol) , betulin, erythrotriol, nonanedioic acid; and fatty acids including myristic acid, palmitic acid, lauric acid It also contains iron pentoxide (canthin-6-one). Originally recorded pharmacological effects Reduce the lungs, high temperature in the large intestine, dilute the thick viscosity in the tissue (by drinking), antibacterial, insecticidal. The right side is effective for treating lung sputum (lung tumor). Modern pharmacology shows that seven monomeric compounds are obtained from hibiscus, among which erythrotriol has the effect of growing tumor cells. Pharmacological application, purpose To reduce the high temperature in the lung and large intestine tissue, and dilute the thick viscosity in the lymphoid tissue to improve the defense function. Trust ancient books The experience of treating lung tumors and modern pharmacological explanations directly affects cancer cells such as lungs and intestines, and cooperates with other drugs to improve the internal environment. -38- 1260226 Description of invention; NO: 19 Name of Chinese herbal medicine Arisaema Tiannanxing heterophyllum B1 According to Chinese Dictionary of Traditional Chinese Medicine, p. 329, Chinese Materia Medica No. 8 (page 504 (Shanghai Science and Technology Press, China) Origin, harvest season, location Jiangxi Production. In October, the tubers were dug out, the soil and stems, leaves and fibrous roots were removed, and they were smashed into a smashing pocket (a barrel-type pharmaceutical appliance), hit the skin, poured out, and then scraped the skin with a bamboo knife. Finally, sulfur was used. Yellow smoked, making it white and dried. Processing, extraction process, method (1) The size of the granules is close to that of Tiannanxing 3KG, the water is immersed, and the water is changed every 2~3 times. When the foam is changed, the water is changed, and 120mg of white peony is added. After soaking for 1 day, change the water to Take out when you cut the opening and feel a slight tingling. (2) Take the foamed Tiannanxing plus ginger slices 1KG to cook 4H, take it out and dry it to 80% dry, slice and dry. (3) Take 1KG powder, and another 2KG is immersed in water for 3H, and heat to separate the liquid. (4) Volatile water, when the remaining 2.5KG, add to the original drug and mix well. (5) Dry at 65 °C. (6) Smashed through a 120 mesh sieve for storage at a young age. The active ingredient contains L-prolyl-L-valine anhydride, uracil, thymine, nicotinamide and many other organisms. Base and cyclic dipeptide compounds and pedatisectine A, B, C, D, E. It also contains more than 30 kinds of amino acids and more than 20 kinds of inorganic trace elements such as daucosterol, /3 - sitostholol, palmitic acid and proline. Originally recorded pharmacological effects Eliminate the cause of abnormal blood vessels and microvascular pressure, calm and relieve phlegm; sputum, dilute the thick tissue of tissue fluid, and penetrate lymphatic tissue. Modern pharmacological experiments, this product has direct killing or inhibition on human lung, liver, stomach, uterus and other cancers. Pharmacological application, purpose To adjust the normal pressure of microvessels, dilute the thick viscosity of tissue fluid, penetrate lymphoid tissue, and synergize with other drugs to improve the cancer environment. 39-

發明說明)MM NO: 20 中草藥名稱 半邊蓮 學名 Lobelia chinensis Banbianlian lour 依 據 中藥大辭典第754頁，中華本草第7冊第 613頁（中國上海科學技術出版社） 產地、採收季節、部位 安徽，福建，臺灣產。夏、秋季割取全草，洗 淨，晾曬使幹。 炮製、萃取過程、方法 (1) 半邊蓮4KG，入鍋水浸3H，分二次煎取 藥液。 (2) 加熱揮發水分，使剩3公升濃汁，入茯苓 粉1KG攪勻。 (3) 60°C 乾燥。 (4) 粉碎過120目篩幼末，防濕包裝收存。 有 效成分 全草含生物鹼，主要為L-山梗菜鹽 (L-lobeline)，山梗菜綱鹽（lobelanine),山梗 菜醇鹽（lobelanidlne)，異山梗菜酮鹽 (isolobelanine),即去曱山梗菜顚I鹽，黃酮武， 皂甙，氨基酸，多糖，菊糖（inulin),對一羥基 苯甲酸（ρ-hy-droxyacid)和琥ί白酸 (succinicacid)。根莖含半邊蓮果聚糖 (lobelinin) 〇 原記載藥理作用 平降組織内偏高溫度，啟動防禦器官，促進 解毒功能（清熱解毒）。增進水分代謝，消除 腹水，足脛腫脹（利水消腫）。通透器官内部 微淋巴代謝，中和毒素。 現代藥理：有利尿、利膽汁、抗蛇毒等作用， 可治療肝硬化腹水、多種癌症。 藥理應用、目的 通透器官深部微淋巴循環；啟動防禦器官， 促進解毒功能。1976年發明人曾於臺灣南 部七縣市、中醫學術研討會中發表「半邊 蓮之考證與應用」一文;說明其在治療方劑 中的功效；可惜因為某種因素，而不被認同； 且由後續之研究者撰文述其「毒性」，且被 收錄於「臺灣有毒植物志」書中。 -40- 1260226 發明說明 NO: 21 中草藥名稱 白薇 學名 Ampelopsis joponica bailian (thunb) makino 依 據 中藥大辭典第691頁，中華本草第5冊第 276頁（中國上海科學技術出版社） 產地、採收季節、部位 安徽、江西產。春、秋季採挖，除去莖及鬚 根，洗淨，縱切成兩瓣，曬乾。 炮製、萃取過程、方法 (1) 6KG洗淨，1KG研為細末，另5KG研為 粗粒，入鍋水浸，加熱以70 °C為限，經 3H。分3次泄下浸液。 (2) 加熱揮發水分，剩3公升濃液，入原藥末 1KG攪勻。 (3) 65°C 乾燥。 (4) 粉碎過120目篩為幼末收貯。 有 效成分 含枯質和澱粉灑石酸（tartaric acid)，/3 -榖 甾醇（冷-sitosterol)，延胡索酸（fumaric acid)，胡蘿蔔武(daucosterol)。 原記載藥理作用 調降組織内的異常高溫，促進淋巴結及其 它防禦系的解毒作用，解除器官韌帶及結 締組的緊束狀態，加速組織潰瘍的癒合。現 代藥理實驗，說明有抗菌作用。1992年李廣 勛氏所述白蔹之體外試驗，對人宮頸癌細 胞培養系JTC-26有抑制作用，證明有抗癌 效應。 藥理應用、目的 深入淋巴、防禦組織，以舒緩、解毒的作用， 配合他種藥物，改變癌環境。 1260226 發明說明_胃 NO: 23 中草藥名稱 石葦 學名 Pyrrosia sheareri Shiwei (Bak) ching 依 據 中藥大辭典第579頁，中華本草第2冊第 253頁（中國上海科學技術出版社） 產地、採收季節、部位 廬山石葦、臺灣、福建產。全年均採收， 洗淨、曬半幹、再陰乾。 炮製、萃取過程、方法 (1) 石葦8KG，入鍋水浸8H，加熱分二次煎取 藥液。 (2) 加熱揮發水分,3公升時入茯荟粉1KG 攪勻。 (3) 65°C 乾燥。 (4) 粉碎過120目篩為幼末收貯。 有 效成分 全草含裏白嫦（diploptene)，忙果武 (mangiferin)，香草酸(vanillic acid)，原兒茶 酸（protocatechuic acid),延胡索酸（Furnaric acid)，咖啡酸（caffeic acid)，/3 穀甾醇（/3 -sitosterol)，蔬糖（sucrose)，異松果武 (isomangiferin)，綠原酸（chlorogenic acid) 原記載藥理作用 鬆弛攝護腺緊張,利尿；消退膀胱、尿道、攝 護腺的發炎病象，治療膀胱、尿道出血。現 代藥理研究，對下腹腔内之多種菌體、病毒 有抑制作用。其杧果甙(mangiferin)有較強 的抗單純皰療病毒的作用，能阻止病毒在 細胞内複製。對於化學療法、放射線療法 引起的白細胞下降，有使其升高的作用；可 增強機體吞噬細胞能力。 藥理應用、目的 改善下腹部臟器發炎、緊束病象，協同他藥， 增強防禦功能。 -43- 1260226 NO: 24 中草藥名稱 乳香 學名 Boswellig carterii ruxiang birdw 依 據 中藥大辭典第1379頁，中華本草第5冊第 17頁（中國上海科學技術出版社） 產地、採收季節、部位 主產於希臘、土耳其等國的進口中藥，是切 傷乳香樹皮後，流出的油膠樹脂。 炮製、萃取過程、方法 (1) 乳香，以燈心草，煅制過者4KG，入鍋水 浸3H，加熱分二次煎取藥液。 (2) 加熱揮發水分，剩3公升乳糜色濃液， 入1KG茯苓粉攪勻。 (3) 50°C 乾燥。 (4) 粉碎過100目篩為末，密封收貯。 有 效成分 乳香樹含樹脂60%-70%，主要成分為遊離 α，/3 -乳香脂酸（α，冷-boswellicacid) 33%， 乳香樹脂烴（〇libanoresene)33%，含樹脂 27%-35%，樹膠為***雜多糖酸 (arabicacid)的#5鹽和鎂鹽20%,含揮發油 3%-8%,呈淡黃色，有芳香，含多種烯、醛、 酮的成分。 原記載藥理作用 促進血液、淋巴液的循環，消除組織間淋 巴、血栓的異常聚集;鎮痛，消腫。 藥理應用、目的 促進血液、淋巴的正常循環，改善防禦器官 功能，配合他藥，排除血栓，癌細胞及其它異 常物質。MM NO: 20 Chinese herbal medicine name Lobelia chinensis Banbianlian lour According to the Chinese Medicine Dictionary 754, Chinese Materia Medica No. 7 (page 613 (China Shanghai Science and Technology Press) Origin, harvest season, location Anhui, Fujian , produced in Taiwan. Cut the whole grass in summer and autumn, wash it, dry it and dry it. Processing, extraction process, method (1) 4KG of Lobelia, 3H in boiling water, and decoction of the liquid. (2) Heat the volatile water to make 3 liters of concentrated juice, and mix well with 1KG. (3) Dry at 60 °C. (4) The 120-mesh sieve is crushed and the moisture-proof packaging is stored. The active ingredient whole grass contains alkaloids, mainly L-lobeline, lobelanine, lobelanidlne, isolobelanine, which is the mountain. Stew 顚I salt, flavonoids, saponins, amino acids, polysaccharides, inulin, p-hy-droxyacid and succinic acid. The rhizome contains lobelinin. The original pharmacological action is to lower the temperature in the tissue, activate the defensive organ, and promote detoxification (clearing and detoxifying). Improve water metabolism, eliminate ascites, swelling of the ankles (swelling water and swelling). It penetrates the micro-lymphatic metabolism inside the organ and neutralizes the toxin. Modern pharmacology: diuretic, bile, anti-venom, etc., can treat cirrhosis ascites, a variety of cancer. Pharmacological application, purpose To penetrate the deep micro-lymphatic circulation of the organ; to activate the defensive organ and promote the detoxification function. In 1976, the inventor published a paper entitled "Research and Application of Lobelia" in the Seven Counties and Cities of Southern Taiwan, in the Chinese Medicine Symposium; explaining its efficacy in therapeutic prescriptions; unfortunately, it was not recognized because of certain factors; Subsequent researchers wrote about "toxicity" and were included in the "Taiwan Toxic Flora" book. -40- 1260226 Description of invention NO: 21 Chinese herbal medicine name Baiwei scientific name Ampelopsis joponica bailian (thunb) makino According to Chinese Pharmacy Dictionary page 691, Chinese Materia Medica No. 5, page 276 (Shanghai Science and Technology Press, China) Origin, harvest season , parts of Anhui, Jiangxi. In spring and autumn, the stems and roots are removed, washed, cut into two petals, and dried. Processing, extraction process, method (1) 6KG washing, 1KG grinding is fine, another 5KG grinding is coarse, boiling in water, heating is limited to 70 °C, after 3H. Dispense the immersion liquid in 3 times. (2) Heat the volatile water, leaving 3 liters of concentrated solution, and mix well at the end of the original drug 1KG. (3) Dry at 65 °C. (4) Smashed through a 120 mesh sieve for storage at a young age. Effective ingredients contain tartaric acid, tartaric acid, cold-sitosterol, fumaric acid, daucosterol. The original recorded pharmacological effects reduce the abnormal high temperature in the tissue, promote the detoxification of lymph nodes and other defense systems, relieve the tight band of the organ ligament and connective group, and accelerate the healing of tissue ulcers. Modern pharmacological experiments indicate an antibacterial effect. In 1992, Li Guangxun's in vitro test of Angelica sinensis inhibited human cervical cancer cell line JTC-26, demonstrating an anticancer effect. Pharmacological application, purpose Deep into the lymph, defense tissue, to soothe, detoxification, with other drugs to change the cancer environment. 1260226 Description of invention_Stomach NO: 23 Name of Chinese herbal medicine Pyrrosia sheareri Shiwei (Bak) ching According to Chinese Medicine Dictionary No. 579, Chinese Materia Medica No. 2, page 253 (Shanghai Science and Technology Press, China) Origin, harvest season, The site is located in Shishan, Taiwan, and Fujian. Harvested throughout the year, washed, dried in the sun, and then dried. Processing, extraction process, method (1) Dendrobium 8KG, into the pot water immersion 8H, heating and sub-frying the liquid. (2) Heat the volatile water, and mix it into the 1KG powder at 3 liters. (3) Dry at 65 °C. (4) Smashed through a 120 mesh sieve for storage at a young age. The active ingredient whole grass contains diploptene, mangiferin, vanillic acid, protocatechuic acid, Furnaric acid, caffeic acid, /3 valley Sterol (/3 -sitosterol), sucrose, isomangiferin, chlorogenic acid, original pharmacological effects, relaxation of prostate, diuresis, regression of bladder, urethra, prostate Inflammatory disease, treatment of bladder, urethra bleeding. Modern pharmacological studies have inhibitory effects on a variety of bacteria and viruses in the lower abdomen. Its mangiferin has a strong anti-pseutic virus effect and prevents the virus from replicating in cells. For leukopenia caused by chemotherapy and radiotherapy, it has an effect of increasing it; it can enhance the ability of the body to phagocytic cells. Pharmacological application, purpose To improve the inflammation of the lower abdomen organs, tight disease, synergy with other drugs, enhance defense function. -43- 1260226 NO: 24 Chinese herbal medicine name Boswellig carterii ruxiang birdw According to the Chinese Medicine Dictionary 1379, Chinese Materia Medica No. 5, page 17 (Shanghai Science and Technology Press, China) Origin, harvest season, parts mainly produced in Greece Imported Chinese medicines in countries such as Turkey are oil gelatin resins that flow out after slicing bark of bark. Processing, extraction process, method (1) frankincense, with rush, calcined 4KG, into the pot water immersed 3H, heated to sub-duce the liquid. (2) Heat the volatile water, leaving 3 liters of milky color liquid, and mix well with 1KG powder. (3) Dry at 50 °C. (4) Smash the 100 mesh sieve to the end, seal and store. The active ingredient, Boswellia sinensis, contains 60%-70% resin, the main component is free α, /3 - succinic acid (α, cold-boswellic acid) 33%, mastic resin hydrocarbon (〇 libanoresene) 33%, resin containing 27%-35 %, the gum is 20% of the #5 salt and magnesium salt of arabic acid, and contains 3%-8% of volatile oil. It is light yellow, aromatic, and contains various alkene, aldehyde and ketone components. The original recorded pharmacological effects promote the circulation of blood and lymph, eliminate the abnormal accumulation of lymphocytes and thrombus between tissues; analgesia and swelling. Pharmacological application, purpose To promote the normal circulation of blood and lymph, improve the function of defensive organs, and cooperate with other drugs to eliminate blood clots, cancer cells and other abnormal substances.

-44- 1260226 厂___：_ 發明說明®Μ NO: 25 中草藥名稱 沒藥 學名 Commiphora Myrrha Moyao Engl 依 據 中藥大辭典第1167頁，中華本草第5冊第 26頁（中國上海科學技術出版社） 產地、採收季節、部位 產於「索馬尼亞」國，橄欖科植物，沒藥樹的 樹幹皮部滲出的油膠樹脂；自古即系進口 中藥。 炮製、萃取過程、方法 (1) 沒藥、以「燈心草」（juncus effusus L. Var)煅制過者4kg，入鋼水浸3h，加熱分 二次煎取藥液。 (2) 加熱揮發水分，剩3公升濃液，入1kg茯 苓粉攪勻。 (3) 50°C 乾燥。 (4) 候冷，粉碎過100目篩，密封收貯。 有 效成分 含樹脂25%-35%，揮發油2.5%-9%，樹膠約 57%_65%，樹膠水解得***糖，半乳糖和 木糖。揮發油在空氣中易樹脂化，含酚，醛， 烯成分，並含多種呋喃倍半萜類化合物。 原記載藥理作用 促進血液循環，排除循環内異質的障礙；以 疏通而達止痛效果。消除結締組織的異常 腫脹。現代藥理研究證實，有調降血脂，膽固 醇，防止動脈壁斑塊形成的作用。可抑制肝 勻漿膽固醇的形成。 藥理應用、目的 促進血液的正常循環，協同他藥，排除毒 素、細菌、癌因子等有害物質。 NO: 27 中草藥名稱 敗醬 學名 Patrinia Villosa Baijiang (thunb.) juss 依 據 中藥大辭典第1340頁，中華本草第7冊第 570頁（中國上海科學技術出版社） 產地、採收季節、部位 四川、福建產。夏季採收，拔起全草，洗淨、 曬乾。 炮製、萃取過程、方法 (1) 8kg洗淨、切段，入鋼水浸8H，加熱分二 次煎取藥液。 (2) 加熱揮發水分，剩3公升濃液時，入茯苓 粉1kg攪勻。 (3) 45°C 乾燥。 (4) 粉碎、過120目篩為幼末收貯。 有 效成分 白花敗醬含白花敗醬甙（villoside)，馬錢子 甙（loganin)，莫羅忍冬武（morroniside)，白花 敗醬醇（villosol)，白花敗醬醇甙 (villosolside)，齊墩果酸，棕櫚酸 (palmiticacid)，還含肌醇（inositol) 〇 原記載藥理作用 調降偏高體溫，增進防禦系統解毒功能；排 除血栓、膿液，現代藥理有鎮靜、抗菌、抗 病毒作用。高淑娟等氏在1992年「天津中 醫」裏發表試驗報告，謂100%敗醬液加入 10mg内毒素，可降低毒素活性，減毒倍數為 8.7， 藥理應用、目的 敗醬的藥理作用，在下腹部器官中最為顯 著，用以為清涼退熱，排膿解毒，使局部環境 趨向正常。 1260226 發明說明$賣胃 NO: 28 中草藥名稱 白某 學名 Angelica dehurica Baizhi 依 據 中藥大辭典第675頁，中華本草第5冊第 883頁（中國上海科學技術出版社） 產地、採收季節、部位 四川、浙江產，8-10月下旬，候葉枯萎時採 收，抖去泥土，烘乾。 炮製、萃取過程、方法 (1) 6KG洗淨，切片，1KG研為細末，另5KG 入鍋水浸，加溫以70°C為限，經8H，分三 次泄下藥液。 (2) 加熱揮發水分，剩3公升黃色濃液時入 原藥末1KG攪勻。 (3) 45°C 乾燥。 (4) 粉碎，過120目篩為幼末收貯。 有 效成分 含歐前胡内酯（imperatorin)等四種前胡内 酯，氧化前胡素（oxypeucedanin)，等三種前 胡素，白當歸素（byakangelicin),白當歸腦 (brakangclicol)，新 白當歸 腦 (neobyakangclicol)，珊瑚菜素（phellopterln)， 花椒毒盼（xanthotoxol)，香柑内脂 (bergapten)，補骨脂素（cnidilin)，栓翅芹稀 醇(pabulenol)等多種香豆精類成分。還含 有穀留醇（sitosterol),棕櫚酸(palmitic acid) 及鈉、鎂、鈣、鐵、磷等11種元素。 原記載藥理作用 抗微生物，治感冒風寒，抗炎、解熱。祛除導 致微血管壓力異常的病因（祛風）;促進局部 組織的水分代謝（利濕），消除鼻咽腔粘膜炎 腫，鎮痛。 藥理應用、目的 引導其它藥物到達頭部，胸部，使發揮抗癌， 治癌的效能。袪除微血管壓力異常的病因， 改善組織水分代謝作用，抵禦外在環境的 侵襲。 -48- 1260226 發明說明_胃 NO: 29 中草藥名稱 射幹 學名 Belamcanda chinensis shegan (L.) DC 依 據 中藥大辭典第1883頁，中華本草第8冊第 256頁（中國上海科學技術出版社） 產地、採收季節、部位 福建、臺灣產，春、秋季挖掘根莖，洗淨曬半 幹搓去鬚根，再曬至全幹 炮製、萃取過程、方法 (1) 5kg洗淨,入漿水（米飯湯隔24h後之湯 液）浸24h，取出漂洗，切片；入锅水浸、加 熱分二次煎取藥液。 (2) 加熱揮發水分，剩3公升時入茯苓粉 1kg攪勻。 (3) 65°C 乾燥。 (4) 粉碎過120目筛為細末收貯。 有 效成分 含射幹定(belamcandin)，鳶尾武(lridin)鳶 尾黃顚I武（tectoridin)，鳶尾黃_ (tectorigenin) 〇 原記載藥理作用 抗炎、解熱，袪痰,清利咽喉炎痛，通透淋巴， 消散淋巴結核。古籍記載，用本品治療肝、 胰腫硬（瘧母，征痞）有效.現代藥理，有抗炎， 解熱，祛痰，抗微生物（炭疽桿菌，白喉桿菌， 傷寒桿菌，人型結核桿菌），以及流感病毒等 作用。 藥理應用、目的 通透淋巴，抗炎，解熱，袪痰，抗殺侵襲機體的 部分微生物，改善惡劣環境，間接增進防禦 功能及進度。 -49- 1260226 NO: 30 中草藥名稱 蒲公英 學名Taraxacum Pugongying mongolicum Hand Mazz 依 據 中藥大辭典第2459頁，中華本草第7冊第 986頁（中國上海科學技術出版社） 產地、採收季節、部位 福建、臺灣產。4〜5月開花前或剛開花時 連根挖取，洗淨、曬乾。 炮製、萃取過程、方法 (1) 6kg洗淨，入锅水浸3h，加熱分二次煎取 藥液。 (2) 加熱揮發水分，剩3公升時入茯苓粉1kg 攪勻。 (3) 65°C 乾燥。 (4) 粉碎過120目篩為細末收貯。 有 效成分 全草含蒲公英留醇（taraxasterol)，膽碱 (choline),菊糖(inulin)，果膠(pectin)等。 原記載藥理作用 促進淋巴組織的通透性，排除機體内的有 毒物質。偏高溫度、發炎、腫脹、現代藥 理說明，有抗病原微生物、抗胃潰瘍、利 膽、保肝等作用，並有啟動巨噬細胞，抗腫瘤 的藥效。 藥理應用、目的 自古即用為淋巴結腫硬的有效藥，在促進 淋巴組織的通透性，協同他藥，解除淋巴内 毒素，偏高溫度、炎腫方面，已有一定的作 用0 -50- 1260226 發明說明r續頁 NO: 31 中草藥名稱 螺厗草 學名Lemmaph yllum luoyancao microphyllum presl 依 據 中藥大辭典第1322頁，中華本草第2冊第 228頁（中國上海科學技術出版社） 產地、採收季節、部位 臺灣產，中藥大辭典名「抱樹蓮」。全年均 可採收，洗淨、曬乾。 炮製、萃取過程、方法 (1) 6kg洗淨，入锅水浸8h，加熱分二次煎取 藥液。 (2) 加熱揮發水分，剩3公升時入茯苓粉1kg 攪勻。 (3) 65°C 乾燥。 (4) 粉碎過120目篩為細末收貯。 有 效成分 含α _芒柄花二烯（a -onoceradiene)等七種 三菇化合物；還含有蕨甾醇(pterosterone)等 三種错體化合物。 原記載藥理作用 清除血液内激進成分，調降偏高體溫，增進 水分代謝功能，利尿，輔助防禦、解毒、殺蟲 等功能。舊醫藥典籍記載，有消除下腹腔内 腫塊，淋巴結核，乳癌等作用。經驗上對於痔 瘡、腸炎、便閉以及泌尿系疾患的療效頗 顯著。 藥理應用、目的 清除下腹腔内器官的發炎病象；並可通透 胸、肺部淋巴結，促進淋巴正常循環，加速治 癌進度。 -51- 1260226 發明說明續頁 NO: 32 中草藥名稱 皂笑 學名 Cleditsia sinensis lam zaojia 依 據 中藥大辭典第1144頁，中華本草第4冊第 480頁（中國上海科學技術出版社） 產地、採收季節、部位 四川產。秋季果實成變黑時採摘，只選略扁， 彎曲作鐮刀狀者（豬牙皂），曬乾。 炮製、萃取過程、方法 (1) 4KG修剪去其弦邊，蜜水炒透，1KG曬 乾研末，另3KG入鍋水浸3H，加熱分二 次煎取藥液。 (2) 加熱揮發水分，剩2.5公升濃液時入原 藥末攪勻。 (3) 45°C 乾燥。 (4) 粉碎過100目篩為細末，密封收貯。 注·.粉末有刺激鼻粘膜的催嚏性，工作人員 需帶口罩。 有 效成分 含皂莢甙（gledinin)其甙元為皂莢甙元 (gledigenin)，皂莢皂武(gleditschia saponin)，尚含躐醇（ceryl alcohol)，二十九 烧（nonacosane)，正二十七烧（heptacosane)， 豆甾醇（stigmasterol)，穀甾醇（sitosterol),鞣 質(tannin)等。 原記載藥理作用 稀釋組織液及體内稠粘物，祛痰，緩解氣管， 支氣管的痙攣，而有止咳作用；通利鼻腔、咽 喉，以及大小便，解除水分代謝障礙引證的 毒素（濕毒），殺蟲，滅菌。現代藥理說明，有祛 痰、抗菌、溶血等作用。 藥理應用、目的 化痰，稀釋或排除稠粘物（逐飲）的中醫藥很 多，各有它適治的層次、部位；並有它適宜的 配伍。本品主要用以稀釋、排除淋巴結與 肺泡附近的钻稠物；古方配合半邊蓮、麻黃， 對於頑固性肺疾患、肺腺癌，皆能取得一定 的效益。 -52- 1260226 NO: 33 中草藥名稱 獨活 學名 Angelica biserrate Duhuo 依 據 中藥大辭典第1703頁，中華本草第5冊第 877頁（中國上海科學技術出版社） 產地、採收季節、部位 四川產。10-11月，挖出根，去除枯萎莖葉， 抖去泥土，攤晾乾部分水氣後,推放炕樓上， 用柴火熏炕，炕至五成幹時，將每枝順直捏 攏，紮成小捆，再炕至全幹。 炮製、萃取過程、方法 (1) 4KG洗淨，切開，入鍋水浸3H,加熱分二 次煎取藥液。 (2) 加熱揮發水分，剩3公升濃液時入茯苓 粉1KG攪勻。 (3) 65°C 乾燥。 (4) 粉碎過100目篩為末，密封收貯。 有 效成分 含當歸醇（angelol)，當歸素（angelicone glabralactone)，佛手柑内 S旨（bergapten)，歐 芹盼甲醚（osthol),傘形花内脂 (umbelliferone)，東笑菪素（scopoletin)，當歸 酸（angelic acid)，巴豆酸(tiglic acid)，棕摘酸 (palmitic acid)，硬脂酸，油酸，亞麻酸，植物 甾醇，葡萄糖和少量揮發油。 原記載藥理作用 排除引發血管、微血管壓力異常以及水分 代謝障礙的病因（風濕因子）、調升偏低體 溫;鎮痛、解痙。現代藥理實驗，有抗心律失 常，延長血栓形成時間，以及鎮痛，解痙，抗 炎、抗菌的作用。所含呋喃香豆精類成分， 具有抑制P摻入HeLa細胞（人宮頸癌細胞） 的作用，對艾氏腹水癌細胞有殺滅作用。 藥理應用、目的 調整微血管壓力，組織内水分代謝，以及偏 低溫，經驗上及舊籍記載，獨活有深入組織， 改善異常病況的作用。 •53- 1260226 發明說明$賣頁 NO: 34 中草藥名稱 麻黃學名 Ephedra sinica stapf Mahuang 依 據 中藥大辭典第2221頁，中華本草第2冊第 349頁（中國上海科學技術出版社） 產地、採收季節、部位 主產於山西、内蒙古。秋季割取綠色莖枝， 挂通風處使有六成幹，再曬乾，捆住收藏。 炮製、萃取過程、方法 (1) 草麻黃4KG洗淨，切寸斷，入鍋水浸3H， 加熱去上面白色浮沫，分二次煎取藥 液。 (2) 慢火揮發水分，剩3公升濃液，入1KG 茯苓粉攪勻。 (3) 45°C 乾燥。 (4) 粉碎過120目篩為細末收貯。 有 效成分 含左旋麻黃碱（ephedrine)，右旋偽麻黃碱 (pseudoephedrine)，等6種麻黃生碱類；惡吐 酮類生物碱；以及分離出32種化合物的揮 發油；並黃酮類化合物。 原記載藥理作用 發汗解熱，抗炎，利尿，對呼吸系統有平喘，鎮 咳，祛痰的作用。興奮中樞神經，增加神經， 肌肉的傳遞功能。 藥理應用、目的 興奮中樞神經，增加神經，肌肉的傳遞功能， 俾使治癌藥物深入組織，是治療肺癌及淋 巴癌、骨癌必要的藥物。-44- 1260226 Factory___:_ Invention Description®Μ NO: 25 Chinese herbal medicine name No pharmaceutical name Commiphora Myrrha Moyao Engl According to Chinese Medicine Dictionary 1167, Chinese Materia Medica No. 5 (page 26 (Shanghai Science and Technology Press, China) In the harvest season, the parts are produced in the "Somagna" country, the olive plant, the oil gel resin exuded from the trunk of the myrrh tree; since ancient times, it has been imported Chinese medicine. Processing, extraction process, method (1) Myrrh, 4kg of juncus effusus L. Var, immersed in steel for 3h, heated to sublimate the liquid. (2) Heat the volatile water, leaving 3 liters of concentrated liquid, and mix well with 1kg of 茯 苓 powder. (3) Dry at 50 °C. (4) Wait for cold, smash through 100 mesh sieve, seal and store. The active ingredient contains 25%-35% resin, 2.5%-9% volatile oil, 57%-65% gum, and the gum is hydrolyzed to arabinose, galactose and xylose. The volatile oil is easily resinized in the air, contains phenol, aldehyde, and olefin components, and contains various furan sesquiterpenoids. Originally recorded pharmacological effects to promote blood circulation, remove the disorder of heterogeneity in the circulation; to relieve the pain effect. Eliminate abnormal swelling of connective tissue. Modern pharmacological studies have confirmed that there is a role in regulating blood lipids, cholesterol, and preventing the formation of plaques in the arterial wall. It can inhibit the formation of cholesterol in liver homogenate. Pharmacological application, purpose To promote the normal circulation of blood, and to cooperate with other drugs to eliminate harmful substances such as toxins, bacteria and cancer factors. NO: 27 Chinese herbal medicine name Patrinia Villosa Baijiang (thunb.) juss According to the Chinese Medicine Dictionary 1340, Chinese Materia Medica No. 7 (page 570 (China Shanghai Science and Technology Press) Origin, harvest season, location Sichuan, Fujian Production. Harvest in summer, pull up the whole grass, wash and dry. Processing, extraction process, method (1) 8kg washing, cutting section, into the steel water immersion 8H, heating twice to take the liquid. (2) Heat the volatile water. When 3 liters of concentrated solution is left, mix 1 kg of mash powder and mix well. (3) Dry at 45 °C. (4) Crushing and passing through a 120 mesh sieve for storage at the end of the baby. The active ingredient Baihua Sauce contains villoside, loganin, morroniside, villosol, villosolside, olean Acid, palmitic acid (palmiticacid), also contains inositol (inositol) 〇原 Record pharmacological effects to reduce high body temperature, improve the defense system detoxification function; exclude thrombosis, pus, modern pharmacology has sedative, antibacterial, antiviral effects. Gao Shujuan et al. published a test report in "Tianjin Traditional Chinese Medicine" in 1992, saying that 100% of the bad liquid added 10mg of endotoxin can reduce the activity of toxins, and the attenuation ratio is 8.7. Pharmacological application, pharmacological action of the target succulent, in the lower abdomen The most prominent organ is used for cooling and antipyretic, detoxification and detoxification, so that the local environment tends to be normal. 1260226 Description of invention: Selling stomach NO: 28 Chinese herbal medicine name Baiming scientific name Angelica dehurica Baizhi According to the Chinese Medicine Dictionary 675, Chinese Materia Medica No. 5, page 883 (Shanghai Science and Technology Press, China) Origin, harvest season, location Sichuan, Produced in Zhejiang, in the late August-October, when the leaves are withered, they are harvested, shaken off the soil, and dried. Processing, extraction process, method (1) 6KG wash, slice, 1KG research for fine, another 5KG into the pot water immersion, heating at 70 ° C limit, after 8H, three times to vent the liquid. (2) Heat the volatile water. When 3 liters of yellow concentrated solution is left, mix it into the original drug 1KG. (3) Dry at 45 °C. (4) Crushing, passing through a 120 mesh sieve for storage at the end of the baby. The active ingredients include four kinds of pre-caprolactone such as imperatorin, oxypeucedanin, three kinds of praerupin, byakangelicin, white angelica (brakangclicol), new white angelica Brain (neobyakangclicol), coralin (phellopterln), xanthotoxol (xanthotoxol), bergapten, cnidilin, pabulenol and other coumarin ingredients . It also contains 11 elements such as sitosterol, palmitic acid and sodium, magnesium, calcium, iron and phosphorus. Originally recorded pharmacological effects Anti-microbial, cure cold, cold, anti-inflammatory, antipyretic. Eliminate the cause of abnormal microvascular pressure (hurricane); promote local tissue water metabolism (lisol), eliminate mucosal inflammation and analgesia in the nasopharyngeal cavity. Pharmacological application, purpose To guide other drugs to reach the head and chest, so as to exert anti-cancer and cancer-promoting effects. Eliminate the cause of abnormal microvascular pressure, improve tissue water metabolism, and resist the invasion of the external environment. -48- 1260226 Description of the invention _ stomach NO: 29 Chinese herbal medicine name dry name scientific name Belamcanda chinensis shegan (L.) DC According to the Chinese Medicine Dictionary 1883, Chinese Materia Medica Volume 8 page 256 (China Shanghai Science and Technology Press) Origin, Harvest season, location Fujian, Taiwan production, spring and autumn excavation of roots, wash and dry semi-dry to remove the roots, then sun to the full-scale processing, extraction process, method (1) 5kg wash, into the pulp (rice soup After 24 hours, the soup solution was immersed for 24 hours, taken out and rinsed, and sliced; the water was immersed in a pot and heated to separate the liquid. (2) Heat the volatile water, and add 3 kg of glutinous powder to the remaining 3 liters. (3) Dry at 65 °C. (4) The 120 mesh sieve is pulverized for fine storage. The active ingredient contains belamcandin, lridin, tectoridin, tectorigenin, 〇原, pharmacological action, anti-inflammatory, antipyretic, phlegm, clear throat, pain, pass Through the lymph, dissipate lymphatic tuberculosis. According to ancient books, this product is effective in treating liver and pancreas (malaria, sputum). Modern pharmacology, anti-inflammatory, antipyretic, expectorant, anti-microbial (Bacillus anthracis, diphtheria, typhoid bacillus, human tuberculosis) And the role of the flu virus. Pharmacological application, purpose Transparent lymph, anti-inflammatory, antipyretic, phlegm, anti-killing part of the microorganisms invading the body, improving the harsh environment, indirectly enhancing the defense function and progress. -49- 1260226 NO: 30 Chinese herbal medicine name Taraxacum Pugongying mongolicum Hand Mazz According to Chinese Medicine Dictionary 2459, Chinese Materia Medica No. 7 (page 986 (China Shanghai Science and Technology Press) Origin, harvest season, location Fujian, Taiwan Production. 4~5 months before flowering or just after flowering, roots are dug, washed and dried. Processing, extraction process, method (1) Wash 6kg, dip in the pot for 3h, and heat to separate the liquid. (2) Heat the volatile water, and add 1kg of glutinous powder when 3 liters left. Stir well. (3) Dry at 65 °C. (4) The 120 mesh sieve is pulverized for fine storage. Effective ingredients Whole grass contains taraxasterol, choline, inulin, pectin and the like. The original pharmacological action promotes the permeability of lymphoid tissues and eliminates toxic substances in the body. High temperature, inflammation, swelling, modern pharmacological description, anti-pathogenic microorganisms, anti-gastric ulcer, gallbladder, liver protection, etc., and have the effect of initiating macrophages and anti-tumor. Pharmacological application and purpose have been used as an effective drug for lymph node swelling since ancient times. It has a certain effect in promoting the permeability of lymphoid tissue, synergizing with other drugs, relieving lymphatic endotoxin, high temperature and inflammation. 1260226 Description of invention r Continued page NO: 31 Chinese herbal medicine name Lembaph yllum luoyancao microphyllum presl According to Chinese medicine dictionary, page 1322, Chinese herbal medicine, Book 2, page 228 (Shanghai Science and Technology Press, China) Origin, harvest season, The part is made in Taiwan, and the Chinese medicine dictionary is called "Huo Shulian". It can be harvested, washed and dried throughout the year. Processing, extraction process, method (1) Wash 6kg, immerse in a pot for 8h, and heat to separate the liquid. (2) Heat the volatile water, and add 1kg of glutinous powder when 3 liters left. Stir well. (3) Dry at 65 °C. (4) The 120 mesh sieve is pulverized for fine storage. The active ingredient contains seven kinds of three mushroom compounds such as α-onoceradiene; and three kinds of complex compounds such as pterosterone. Originally recorded pharmacological action to remove the radical components of the blood, reduce the high body temperature, improve the function of water metabolism, diuretic, auxiliary defense, detoxification, insecticidal and other functions. The old medical classics record the elimination of intra-abdominal masses, lymphatic tuberculosis, and breast cancer. Experience has been significant in the treatment of acne, enteritis, constipation and urinary disorders. Pharmacological application, purpose To remove the inflammatory disease of the lower abdominal organs; and to penetrate the chest and lung lymph nodes, promote normal circulation of lymph, and accelerate the progress of cancer treatment. -51- 1260226 Description of the Invention Continued NO: 32 Chinese herbal medicine name Soap laughter name Cleditsia sinensis lam zaojia According to the Chinese Medicine Dictionary 1144, Chinese Materia Medica Volume 4, page 480 (Shanghai Science and Technology Press, China) Origin, harvest season, The location is made in Sichuan. When the autumn fruit is blackened, it is only slightly flattened, bent as a sickle-shaped (pork tooth soap), and dried. Processing, extraction process, method (1) 4KG trimmed to the side of the string, honey water fry, 1KG drying dry powder, another 3KG into the pot water immersion 3H, heating two times to take the liquid. (2) Heat the volatile water, and add 2.5 liters of concentrated solution to the original drug and mix well. (3) Dry at 45 °C. (4) The 100 mesh sieve is pulverized into fine powder and sealed and stored. Note · The powder has a stimulating effect on the nasal mucosa, and the staff needs to wear a mask. The active ingredient contains gledinin, which is gledigenin, gleditschia saponin, ceryl alcohol, nonacosane, and twenty-seven (stainless) Heptacosane), stigmasterol, sitosterol, tannin, etc. The original recorded pharmacological action dilutes the tissue fluid and the thick and sticky substances in the body, sputum, relieves the trachea and bronchospasm, and has the effect of relieving cough; Tongli nasal cavity, throat, and urine, relieve the toxins (wet poison) cited by the water metabolism disorder, Insecticide, sterilization. Modern pharmacological explanations have the effects of sputum, antibacterial and hemolysis. There are many traditional Chinese medicines for pharmacological application, purpose, phlegm, dilution or elimination of sticky substances (by drinking), each with its appropriate level and location; and its suitable compatibility. This product is mainly used to dilute and eliminate the thickened matter near the lymph nodes and alveoli; the ancient side cooperates with lobelia and ephedra, and can achieve certain benefits for refractory lung diseases and lung adenocarcinoma. -52- 1260226 NO: 33 Chinese herbal medicine name Single live scientific name Angelica biserrate Duhuo According to the Chinese Medicine Dictionary 1703, Chinese Materia Medica No. 5, page 877 (Shanghai Science and Technology Press, China) Origin, harvest season, location Sichuan. From October to November, excavate the roots, remove the withered stems and leaves, shake off the soil, spread the part of the water and gas, push it on the floor, smoke it with firewood, and when it is dry to 50%, squeeze each branch straight. Get together, tie it into small bundles, and then smash it to dry. Processing, extraction process, method (1) Wash 4KG, cut open, dip 3H into the pot, and fry the liquid twice. (2) Heat the volatile water, and add 3 liters of concentrated liquid to the 茯苓 powder 1KG and mix well. (3) Dry at 65 °C. (4) Smash the 100 mesh sieve to the end, seal and store. The active ingredients include angelol, angelicone glabralactone, bergamot in bergamot, osthol, umbelliferone, scopoletin Angelic acid, tiglic acid, palmitic acid, stearic acid, oleic acid, linolenic acid, phytosterol, glucose and a small amount of volatile oil. Originally recorded pharmacological effects Exclude the cause of blood vessels, microvascular pressure abnormalities and water metabolism disorders (rheumatoid factor), lowering body temperature; analgesia, spasm. Modern pharmacological experiments have anti-arrhythmia, prolonged thrombus formation, and analgesic, antispasmodic, anti-inflammatory, antibacterial effects. The furan coumarin component has the function of inhibiting the incorporation of P into HeLa cells (human cervical cancer cells) and has a killing effect on Ehrlich ascites cancer cells. Pharmacological application, purpose Adjust microvascular pressure, tissue water metabolism, and hypothermia, experience and old records, unique activities have deep tissue, improve the role of abnormal conditions. •53- 1260226 Description of invention: Selling page NO: 34 Chinese herbal medicine name Ephedra sinica stapf Mahuang According to Chinese medicine dictionary, page 2221, Chinese herbal medicine, Book 2, page 349 (Shanghai Science and Technology Press, China) Origin, harvest season The main parts are produced in Shanxi and Inner Mongolia. In the autumn, cut the green stems, and hang the ventilation place to make 60% dry, then dry and bundle the collection. Processing, extraction process, method (1) Wash the grass 4KG 4KG, cut into pieces, dip 3H into the pot, heat to the above white froth, and take the liquid twice. (2) Slowly volatize the water, leaving 3 liters of concentrated liquid, and mix well with 1KG powder. (3) Dry at 45 °C. (4) The 120 mesh sieve is pulverized for fine storage. The active ingredient comprises ephedrine, pseudoephedrine, and other six ephedrine bases; oxatoxin alkaloids; and volatile oils of 32 compounds are isolated; and flavonoids . Originally recorded pharmacological effects Sweat and antipyretic, anti-inflammatory, diuretic, anti-asthmatic, antitussive and expectorant effects on the respiratory system. Exciting the central nervous system, increasing the function of the nerves and muscles. Pharmacological application, purpose Exciting the central nervous system, increasing the function of nerves and muscles, and making cancer treatment drugs deep into tissues are essential drugs for treating lung cancer, lymphoma and bone cancer.

-54- 1260226 發明說明$賣胃 NO: 35 中草藥名稱 升麻 學名 Cimicifuga foetida L Sheng ma 依 據 中藥大辭典第451頁，中華本草第3冊第 175頁（中國上海科學技術出版社） 產地、採收季節、部位 四川產，秋季地上部份枯萎後，挖出根莖，去 淨泥土，曬至八成幹，用火燒去鬚根，再曬至 全幹，撞去表皮及殘存鬚根。 炮製、萃取過程、方法 (1) 6KG浸潤，切片，入鍋水浸3H，加熱分二 次煎取藥液。 (2) 加熱揮發水分，剩3公升時入茯荟粉 1KG攪勻。 (3) 65T：乾燥。 (4) 粉碎過120目篩為細末貯存。 有 效成分 含升麻碱(cimicifugine),水楊酸，鞣質，樹脂， 咖啡酸(caffeicacid)，阿魏酸(ferulic acid)等 及其它不明成分。 原記載藥理作用 解熱，抗炎，解毒;促進淋巴導管的淋巴液上 升，提高肺部呼吸量。疏通末梢血管，使麻疹 病毒透發於表皮。現代藥理說明，升麻有解 熱，降溫，抗炎，抗驚厥，護肝，解痙的作用，升 麻三萜類化合物，能增進淋巴細胞的活性； 升麻提出物能誘導淋巴細胞產生幹擾素。 藥理應用、目的 增進淋巴導管上升動能，增進淋巴細胞活 性，透導淋巴細胞產生幹擾素，在小腸淋巴 結（培氏斑）以及胸腺以上淋巴結裏產生特 殊的作用，故雖非抗癌藥物，卻是治療、腸部 癌、肺癌及頭部諸癌的主導性藥物。 發明說明，續頁 1260226 「藥物製備」 上列經濃縮萃取（方法參閱各藥物說明資料）藥粉，按 所列百分比配合’經混合機充分混合後，加入適當水分擾 微濕，再以打錠機製成每顆0.5gm的錠片，45°C乾燥去水 5 分，裝入玻璃瓶中密封貯存，置於乾燥、陰涼處備用。 「使用方法」 凡進行肝癌、胰腺癌、食道癌、賁口、幽門、胃癌之外 的廣泛性癌種別’經珍斷確定，不論原發、轉移、期別， 10是否經過割、栓、化、放之治療，只要屬於此廣泛性、進 行性的癌症，均可使用。每飯後90min，以白開水吞服（咬 碎亦可）8顆（4gm)，曰服三次，小兒酌減或減半。 「注意事項」 15 經割、栓、化、放療者，須隔10天以上服用，服藥期 間勿再、检、化、放療，勿兼服其它藥物或健康食品，以 免妨礙藥效。禁食蔥蒜靈酒、花椒、魯料、五番料等躁 熱食品。住處不可燃燒蚊香、噴灑滅蚊、殺蟲劑等有毒氣 質；勿作劇烈運動、暫停交際、應酬。 20 .「臨床試驗」 1 ·試驗目的、說明： 在疋規耗内’持續給予「一種治療淋巴結關係型癌症 '中藥複方」内服’以測試其實際療效，並歸納統計之。 -56- I26〇226 ___」 _l 發明說明，續頁 「為顧及參與者寳貴生命、試驗的持續，在過程中、若遇 ▲非癌疾病、偶發症候」時’皆臨時另用藥物處治，作本 式驗内服藥健持續，並不直接影響試驗效果。 編列本中請案「臨床試驗實施例」之f料、播荦，部分 本試驗單位，診斷確據則在各相關醫院之病㈣斷 ，據庫’依臺灣有關法規、再—定時間内有必須保存的規 2·實施例的一定規範： 入案排除··未經設備齊全之三級以内大醫院之科學診我 蜂定者排除。屬於肝癌、胰腺癌、食道癌、胃及賁口癌者 排除。試驗日期不足3療程（每療程12天 恐 評定誤差而排除。 脒 15 20-54- 1260226 Description of invention: Selling stomach NO: 35 Chinese herbal medicine name Cimicifuga foetida L Sheng ma According to Chinese Pharmacy Dictionary 451, Chinese Materia Medica No. 3, page 175 (Shanghai Science and Technology Press, China) Origin, harvest The seasons and parts are produced in Sichuan. After the autumn part of the ground is withered, the roots are dug out, the soil is removed, and the sun is dried to 80%. The roots are burned with fire, and then dried to the whole surface, hitting the epidermis and residual roots. Processing, extraction process, method (1) 6KG infiltration, slicing, boiling in water 3H, heating twice to take the liquid. (2) Heat the volatile water, and add 3 liters of eucalyptus powder to 1KG and mix well. (3) 65T: Dry. (4) The 120 mesh sieve is pulverized for fine storage. The active ingredient contains cimicifugine, salicylic acid, tannin, resin, caffeic acid, ferulic acid and other unidentified ingredients. Originally recorded pharmacological effects Antipyretic, anti-inflammatory, detoxification; promote lymphatic drainage of lymphatic vessels, improve lung respiration. The peripheral blood vessels are dredged to allow the measles virus to permeate the epidermis. Modern pharmacology shows that cohosh has antipyretic, cooling, anti-inflammatory, anticonvulsant, liver protection, antispasmodic effect, cohosh triterpenoids, can enhance lymphocyte activity; cohosh extract can induce lymphocytes to produce interferon . Pharmacological application, purpose to improve lymphatic vessel ascending kinetic energy, increase lymphocyte activity, transduce lymphocytes to produce interferon, produce special effects in small intestine lymph nodes (Pei's plaque) and lymph nodes above the thymus, so although it is not an anticancer drug, it is The leading drug for treatment, intestinal cancer, lung cancer and head cancer. Illustrated, cont. 1260226 "Drug Preparation" The above listed concentrated powder (method refer to each drug description) powder, according to the listed percentages, 'mixed thoroughly after mixing, add appropriate water to disturb the micro-wet, then use the tablet machine Each 0.5gm tablet is prepared and dried at 45°C for 5 minutes. It is sealed in a glass bottle and stored in a dry and cool place. "Usage method" Where a wide range of cancer types other than liver cancer, pancreatic cancer, esophageal cancer, sputum, pylorus, and gastric cancer are determined, regardless of the original, metastatic, and stage, 10 is cut, tied, or smeared. The treatment of the disease can be used as long as it belongs to this extensive and progressive cancer. 90 minutes after each meal, swallowed with boiled water (bite can also be) 8 (4gm), simmered three times, children reduced or halved. "Precautions" 15 Those who have undergone cutting, embolization, chemotherapy or radiotherapy should take more than 10 days. Do not re-examine, treat, or treat radiotherapy during the medication period. Do not take other medicines or health foods together, so as not to interfere with the efficacy. Fasting onions, garlic, wine, pepper, Lu, Wufan, etc. Do not burn odorous mosquitoes, spray mosquitoes, insecticides, etc.; do not exercise vigorously, suspend communication, and socialize. 20 . "Clinical trials" 1 · Purpose of the test: Explain: "Continuously give "a kind of lymph node-related cancer" Chinese medicine compound "intracorporeal" in the treatment of sputum to test its actual efficacy, and summarize the statistics. -56- I26〇226 ___" _l Description of the invention, continuation page "To take into account the valuable life of the participants, the continuation of the trial, in the process, in the case of ▲ non-cancer diseases, occasional symptoms", they are temporarily treated with drugs. This type of internal medicine is healthy and does not directly affect the test results. The materials and sowing of the "Clinical Test Examples" in this case are listed. Some of the test units are diagnosed according to the disease in each hospital (4). According to the relevant regulations of Taiwan, there are Regulations that must be preserved 2. Certain specifications of the examples: Exclusion of the case · The scientific diagnosis of a large hospital within three levels without a complete equipment is ruled out by the beekeeper. It belongs to liver cancer, pancreatic cancer, esophageal cancer, stomach and mouth cancer. The trial date is less than 3 courses (12 days per course of fear) and the error is excluded. 脒 15 20

起乾年月：已受試日為准，自1997年3月2日起，至 =〇2年1G月2日終止；凡合乎上述規範者，不論癌種型、 顏別、療效結果，—律納人實_，並予以統計。 3·療效評定之標準·· 依據1972年中央（巾砌 .The year of dryness: the date of the test, which is subject to the test date, from March 2, 1997 to the end of 2 years, 1G, 2nd; if any of the above criteria, regardless of cancer type, face, efficacy results, The legal person is _ and is counted. 3. Standards for evaluation of efficacy · According to the Central Committee of 1972 (Women.

国俯生邛）關於「中藥治癌症 祕準」通知；分顯效、有效、無效三種。 顯效:症狀基本消失’癌病、縮小一半以上 檢查有明顯好轉。；[級規宕车 、 硯 ^々 見疋+年以上不再復發者；II級規定 2-6各月不再發展者。 有效·症狀有所改善、病基本穩^，規個月以上 者。 無效：症狀及客觀檢查無改善，或短期改善、又有迅速 -57- 1260226The National Government has issued a notice on the "Symbol of Chinese Medicine for Cancer Treatment"; it is effective, effective, and ineffective. Significant effect: Symptoms basically disappeared 'Cancer disease, more than half of the inspections have improved significantly. ; [Class rules car, 砚 ^ 々 see 疋 + years no longer relapse; Level II regulations 2-6 no longer develop each month. Effective · Symptoms have improved, the disease is basically stable ^, more than two months. Invalid: no improvement in symptoms and objective examination, or short-term improvement, and rapid -57- 1260226

發明說明, 惡化者。 m列有祕定之外，再本實施例中 曰應不明確，或失聯而難以評定者，另 「凡文試者 試者症狀有所改善，病«基本敎_過1個1詳」。受 本試驗進行中’突生變化、或回復原 /旦若在 效」。 颉於「無 10 「效率、統計」 符合本試驗規範之癌患共計83人，經試驗結果， 2fi / ^ ^ ι 、有效42人，合計有效者68人，占82% ;無致 12人、不詳者3人，合計無效者15人，占18%。各病者 別人數、效率如下表 積 癌種別 肺 淋巴 〇腔、鼻咽、喉舌 甲狀腺等 人數 17 11 13Description of the invention, a worse person. In addition to the secrets in the m column, in this embodiment, the sputum should be unclear, or it is difficult to assess if it is lost. In addition, the symptoms of the tester are improved, and the disease is basically 敎 _ _ _ _ 1 1 In the course of this experiment, the sudden change, or the return to the original / Dan if it is effective.颉 “No 10 “Efficiency, Statistics” A total of 83 cancer patients meet the test specifications. According to the test results, 2fi / ^ ^ ι, effective 42 people, 68 people in total, accounting for 82%; no 12 people, There are 3 people who are unknown, and 15 people who are invalid in total, accounting for 18%. The number of patients and the efficiency of the patients are as follows. Cancer types, lungs, lymphatic cavity, nasopharynx, mouthpiece, thyroid, etc. Number of people 17 11 13

乳 Ύ 膀脱、攝護腺 -58- 1260226 發明說明_胃Milk thistle, bladder, prostate -58- 1260226

癌）。最高年齡丨919年生（83歲），最低年齡1985年生 (17歲），平均年齡54歲（以2002年計）。診斷確定依 5據··經一級教學醫院者17人，二及區域醫院者58人，三 級地區醫院者8人。 診斷確;t後’經三級以内大醫院、或自服藥物無效而參 與本試驗者73人，直接參與者10人，共計83人。 10 「癌種轉移統計」 說明：L本統計之目的，以實際癌患資料 1:，尤其是上、下部癌種轉移的特性，以及放、化療對 此特性的影響；從而證明本申 ’、 .H月案中「類型機理」的新創 見，以填補治癌論據的不足2桿 15之癌種別。是屬於「進行性」的在本申請案臨床試驗例 資料，而尋肖其「輕性」鱗纽據此83件 上舞、日#J於轉移動態的追查。3. 、疋指橫隔膜以上、包括頸、 上焦癌者有51人，·下焦、是指姨：腔、胸之上部’原發 骨的下部，原發下焦癌者有32人夷放肝：胃以下，包括腎、 敌、是指放射電療；化、 -59- j26〇226cancer). The highest age is 919 years old (83 years old), the lowest age is 1985 (17 years old), and the average age is 54 years (in 2002). The diagnosis was determined according to the data of 17 people in the first-level teaching hospital, 58 in the second and regional hospitals, and 8 in the third-level regional hospitals. The diagnosis was confirmed; after t, there were 73 people who participated in the trial in a large hospital within three levels or ineffective self-medication, and 10 direct participants, a total of 83 people. 10 “Statistics of cancer metastasis” Description: The purpose of this statistical calculation is to compare the characteristics of actual cancer data, especially the characteristics of metastasis of upper and lower cancers, and the effects of radiotherapy and chemotherapy on this characteristic; The new concept of "type mechanism" in the .H case to fill the cancer category of less than two shots. It is a "progressive" clinical trial case data in this application, and it is found that the "light" scales are based on 83 pieces of dance and Japanese #J in the tracking dynamics. 3. There are 51 people with sputum above the diaphragm, including the neck and upper coke cancer. · The lower focus is the lower part of the original bone of the cavity and the upper part of the chest. There are 32 people who have the original underlying cancer. : below the stomach, including kidney, enemy, refers to radiation therapy; Hua, -59- j26〇226

發明說明MM 是指化學藥物滴注療法；該8 3例中、經放、化療者3〗人， ，經放、化絲52人。4.轉下是指原發上焦之癌向下轉移、 二轉移下焦；轉上、是指癌之向上轉移、或轉移上焦；平 ，、是指原發上焦或下焦之癌，橫向轉移附近器官；不轉、 是指癌在原器官不動，或經割除、放、化療之後，仍然再 生、擴散於原器官。 統計圖表：DESCRIPTION OF THE INVENTION MM refers to chemical drug instillation therapy; in the 83 cases, 3 persons were treated with radiotherapy and chemotherapy, and 52 were treated with chemical and silk. 4. Turning down means that the primary metastasis of the cancer is transferred downwards, and the second metastasis is down. If it is turned, it refers to the upward shift of the cancer, or the shift of the focus; the flat, refers to the cancer of the primary focus or the lower focus, horizontal Transfer of nearby organs; does not turn, refers to cancer in the original organs do not move, or after cutting, release, chemotherapy, still regenerate, spread in the original organs. statistic chart:

上焦癌51 A~^ r—^—- 轉下 — 平轉 不轉 經放化療21人 10人 5人 6人 未經放化療30人 ——---- 1人 5人 24人 計51人 11人 10人 30人 下焦癌32人 ----- 轉下 平轉 不—¥ 經放化療10人 5人 3人 2人 未經放化療22人 6人 ---- 3人 13人 計32人 11人 ---- 6人 15人 -60- 1260226 1. 上、下焦癌轉下、轉上之比較： A、 混合（不論是否經化、放療） 上焦癌轉下11/51=0.21，下轉癌轉上11/32=0.34 B、 不經化、放療 5 上焦癌轉下1/30=0.033，下焦癌轉上6/22=0.272 0.21<0·34，0·03<0·27Upper coke cancer 51 A~^ r-^-- turn down - Ping Zhuo does not transfer radiotherapy and chemotherapy 21 people 10 people 5 people 6 people without radiotherapy and chemotherapy 30 people ----- 1 person 5 people 24 people count 51 People 11 people 10 people 30 people under the coke cancer 32 people ----- turn down the level does not - ¥ by radiotherapy and chemotherapy 10 people 5 people 3 people 2 people without radiotherapy and chemotherapy 22 people 6 people --- 3 people 13 people 32 people, 11 people----6 people, 15 people-60- 1260226 1. Comparison of upper and lower coke cancers, turning on: A, mixed (regardless of whether or not chemotherapy, radiotherapy) on the coke cancer turned down 11/51= 0.21, the next turn cancer turned 11/32=0.34 B, no chemotherapy, radiotherapy 5 upper focus cancer turned 1/30=0.033, lower focus cancer turned 6/22=0.272 0.21<0·34,0·03&lt ;0·27

則上焦癌轉下<下焦癌轉上；在不經化、放療之情況下， 上焦癌轉下是下焦癌轉上的1/8。 2. 上、下焦癌轉移（包括平轉）之比較： 10 A、混合（不論是否經化、放療） 上焦癌轉移 11/51 + 10/51=21/51=0.412 下焦癌轉移 11/32+6/32=17/32=0.531 B、不經化、放療 上焦癌轉移 1/30+5/30=6/30=0.200 15 下焦癌轉移 6/22+3/22=9/22=0.409 0·412<0·53，0·20<0·41Then the upper coke cancer is turned down and the lower coke cancer is turned on; in the case of non-chemotherapy and radiotherapy, the upper coke cancer is turned down to 1/8 of the lower coke cancer. 2. Comparison of upper and lower metastasis metastasis (including blunt rotation): 10 A, mixed (regardless of whether or not chemotherapy, radiotherapy) Upper coke cancer metastasis 11/51 + 10/51=21/51=0.412 Lower coke cancer metastasis 11/32 +6/32=17/32=0.531 B, non-chemotherapy, radiotherapy on focal cancer metastasis 1/30+5/30=6/30=0.200 15 undercarcinal metastasis 6/22+3/22=9/22= 0.409 0·412<0·53,0·20<0·41

則上焦癌之轉移，略少於下焦癌之轉移；在不經化、放 療之情況下、上焦癌之轉移是下焦癌轉移的1/2。 3. 化、放療與不經化、放療之轉上、轉下，以及轉移 20 的比較： A、上焦轉下與下焦轉上； 上焦經化、放轉下10/21=0.476 上焦不經化、放轉下1/30=0.033 下焦經化、放轉上5/10=0.5 -61- 1260226 發明說明續頁 下焦不經化、放轉上6/22=0.272 B、上焦轉移（含平轉）與下焦轉移； 上焦經化、放轉移 10/21+5/21 = 15/21=0.71 上焦不經化、放轉移1/30+5/30=6/30=0.20 5 下焦經化、放轉移5/10+3/10二8/10=0.80The metastasis of the oncogenic cancer is slightly less than the metastasis of the lower coke cancer; in the absence of chemotherapy and radiotherapy, the metastasis of the upper coke cancer is 1/2 of the metastatic cancer metastasis. 3. Comparison of chemotherapy, radiotherapy and non-chemotherapy, radiotherapy, transfer, and transfer 20: A. Upper focus and lower focus turn; Upper focus, 10/21=0.476 Without treatment, release 1/30=0.033 under coke formation, release on 5/10=0.5 -61-1262626 Description of the invention Continued page under focus, turn on 6/22=0.272 B, upper focus transfer (including translation) and lower coke transfer; upper cokeization, release transfer 10/21+5/21 = 15/21=0.71 upper focus is not converted, release transfer 1/30+5/30=6/30=0.20 5 under the coke, transfer 5/10 + 3/10 two 8/10 = 0.80

下焦不經化、放轉移6/22+3/22=9/22二0.409 上焦經化、放與否之比例 轉下-0·476>0·033 = 14.5 倍 轉移-0·710〉0.20=3·5 倍 10 下焦經化、放與否之比例 轉上-0·50>0.27=1·8 倍 轉移-0·80>0.41 = 1·9 倍 結論：1.由上1之統計可知，上焦癌轉下之0.21<下焦 癌轉上之0.34 ;在不經化、放療之情況下，上焦癌轉下的 15 0.03、只是下焦癌轉上的1/8。The lower focus is not converted, and the transfer is 6/22+3/22=9/22 two 0.409. The ratio of the upper coke, release or not turns down -0·476>0·033 = 14.5 times transfer-0·710>0.20 =3·5 times 10 times the ratio of coke, release or not is turned to -0·50>0.27=1·8 times transfer-0·80>0.41 = 1·9 times Conclusion: 1. From the statistics of the above 1 0.21 of the upper focus cancer turned to 0.34 of the lower focus cancer; in the case of non-chemotherapy and radiotherapy, 15 0.03 of the upper focus cancer turned, only 1/8 of the lower focus cancer turned.

2. 由上2之統計可知，上焦癌轉移的0.412略少 於下焦癌轉移的0.53 ;在不經化、放療的狀況下，上焦癌 之轉移是下焦癌轉移的1/2。 3. 由上3之統計可知，經放、化療之上焦癌轉 20 下，是不經化、放療轉下的14.5倍，轉移是3.5倍，故上 焦癌之化、放療顯然有催促轉下、轉移的敝端。經化、放 療的下焦癌，轉上是不經化、放療的1.8倍，轉移是1.9倍， 在下焦癌種具有轉上本能的影響下，其嚴重性遠低於上焦 癌種。 -62- 1260226 ^：_ 發明說明$賣胃2. According to the statistics of the above 2, the 0.412 of the metastatic cancer metastasis is slightly less than 0.53 of the lower focal cancer metastasis; in the absence of chemotherapy and radiotherapy, the metastasis of the upper coke cancer is 1/2 of the metastatic cancer metastasis. 3. According to the statistics of the above 3, after the radiotherapy and chemotherapy, the cancer is turned to 20 times, which is 14.5 times that of non-chemical and radiotherapy, and the metastasis is 3.5 times. Therefore, it is obvious that the oncogenic cancer and radiotherapy are urged to turn. The end of the transfer. The lower coke cancer after chemotherapy and radiotherapy is 1.8 times that of non-chemotherapy and radiotherapy, and the metastasis is 1.9 times. Under the influence of the instinct of the lower coke cancer, its severity is much lower than that of the upper coke cancer. -62- 1260226 ^:_ Invention Description $Sell stomach

4.綜上所述，茲再重點歸納為A、上焦癌種向 下轉移之能度甚低，且低於本位之平轉、上轉。B、上焦 癌之化、放療甚不利於癌患，經化、放療後、轉移能度增 加3.5倍，向下轉移能度竟高達14.5倍。C、下焦癌種本就 5 具有向上轉移的高能度，在不經化、化療的狀況下，是上 焦癌種向下轉移的8倍；經化、放療後；其轉上、轉移的 能度影響略少。D、本統計資料因環境因素而略有不足，乃 望較具規模之癌研機構，依此方式再行統計，必有更為確 鑿之發現。 10 「臨床試驗標準例」 在本發明書内，僅舉出其中九個案例作簡要說明，其餘 65案件及詳細說明，如附件一所示。 (1)、N0.1洪XX小姐、肺癌、1985年生（17歲） 15 2000年12月，經台南某二級大醫院科學檢驗，發現右 膝蓋骨下骨癌，12月26日截切右下肢，並施予全程化療 治療。4. In summary, it is further summarized that the ability of A and the upper focus cancer to transfer downward is very low, and it is lower than the standard. B. Upper focus Cancer treatment and radiotherapy are not conducive to cancer patients. After chemotherapy and radiotherapy, the transfer energy is increased by 3.5 times, and the downward transfer energy is as high as 14.5 times. C. The lower coke cancer species has a high energy level of upward metastasis. Under the condition of no chemotherapy or chemotherapy, it is 8 times of the downward transfer of the upper coke cancer species; after the chemotherapy and radiotherapy; The degree of influence is slightly less. D. This statistic is slightly insufficient due to environmental factors. It is expected that a larger-scale cancer research institution will conduct more statistics in this way, and there must be more convincing findings. 10 “Clinical Test Standards Example” In the present invention, only nine cases are briefly described, and the remaining 65 cases and detailed explanations are shown in Annex 1. (1), N0.1 Hong XX Miss, lung cancer, born in 1985 (17 years old) 15 In December 2000, through a scientific examination of a second-level hospital in Tainan, the right knee bone bone cancer was found, and the right lower limb was cut on December 26 And give full chemotherapy treatment.

2001年8月，因咳嗷聲緊促，呼吸障礙，經原院檢驗， 發現癌細胞轉移肺部，即行開刀，因見癌體機超大，難以 20 手術，故再行縫合。 2001年9月14日參與本試驗，至同年10月26日主症 狀明顯改善，已不覺痛苦、4療程後，主症狀完全消失， 後即斷、續用藥。2002年2月9日，右足骨癌切除處、腫 熱發炎，用本發明藥物、略加他藥，二療程内痊愈。 -63- 1260226 .___：_ 發明說明 (2)、NO、9、詹 XX 女士、肺癌、1942 年生（60 歲） 1995年乳腺癌切除；1998年11月轉移右鎖骨上淋巴 癌，經影化某一級示教醫院檢驗確定，並施與化療、放療。 2〇〇〇年4月轉移左腋下，經原院切除，再予化療。2〇〇1年 5 1月再檢，發現轉移為肺癌。 2001年2月1日參與本試驗；症候a、喘急，胸中壓迫 感，咳嗷則胸内疼痛。B、腹腰腫脹感，下腹按之痛。c、右 手臂因化放療過敏反應，而淋巴腫脹、象皮腫。D、足脛腫。 10 15 20 2001年3月23日，主症狀或痊或明顯改善，經原醫院檢 驗，癌腫粒不再發生，增大，情況穩定；至療程結束，諸證狀多 痊，唯化、放療後遺之右手臂象皮腫改善有限。 (3)、N0.18,陳XX女士，淋巴癌，1951年生（51歲） 先是1999年3月，經台南某二級專科醫院宮頸癌檢 確，同月π日開刀切除宮巢、放射電療28次，接續化療 每周一次。病況未見改善，乃轉以尾酒療法治療無效。化 療後I5天，足職，右上肢齡賴_;再轉人高雄某二級 大醫院檢驗，證實已轉移入淋巴、骨髓内，宣佈右手已殘癆 亚移入安寧病房，以鱗劑止痛，作為最後安頓。 ， 續疼痛，須服 =難=2=七㈣㈣匙，虛弱， ，七屑胛之疼痛，在半療程内 -64- 1260226 —__l__I__ 發明說明,續胃 明顯改善，不用麻醉劑，下腹舒坦，二便通暢。9月ό日主症狀 再改善，無痛苦感受，左瑣骨上淋巴癌腫塊消退二分之一，右 手已可活動。後因誤食某直銷的健康食品，而癌腫塊再腫， 右手臂又劇痛，用藥至1〇月17日，項下癌塊消，右手臂複元， 5腰背持續之疼痛完全消失。η Θ 5日左瑞骨上癌塊僅存 0.2CM，其餘生活、起居一如健康人。至2〇〇2年6月不復發。 (4)、Νο·23,郭XX女士，淋巴癌，1946年生（56歲） 1999年1〇月，南部某一級教學醫院診斷確定為膀 胱癌，並施與開刀治療;2000年5月追縱檢查，發現轉移直腸 1〇癌，開刀，因故不予切除，而施行化學滴注5次，不久，左瑣骨上 出現淋巴癌腫塊，約3.5CM，確定轉移為淋巴癌，並予插腎導 尿管，背尿袋，原院束手。 2001年3月1〇日參與本試驗，主症狀a、左瑣骨 上淋巴癌腫塊約3.5CM，B、下腹絞痛、腰臀酸痛不支。c、 15大便先急後重，排便困難。其它食欲不佳，虛弱、體力不支等。 2001年3月21日，B、C症狀明顯改善。3月28 日A之淋巴癌腫塊漸消，但腰臀酸痛又起。4月8日主症狀 再改善。5月9日服用直銷健康食品（品物同前例），致淋巴 癌再腫。5月16主副症狀持續改善,並維持3〇天以上。 20 (5)、N〇·29,溫 XX 先生，口 腔癌，1924 年生（78 歲） 宿有糖尿病，1998年12月16日經某二級大醫院診 斷為口腔癌，經原卩元樂物治療，以及服用多種藥物，病況仍持 續惡化。 1999年10月17日參與本試驗；主症狀a、口腔近 1260226 _i__i _ 發明說明，續頁 B;?，左頰，齒銀間呈現癌腫粒，領下腺腫硬，開啟障礙。 動銀二中癌脹。C、夜間咳漱。其它疲勞倦息，體力不支，行 f始、访。^99年1M 31日潰爛病象改善，領下腺腫消，癌脹， _ 月17日主症狀再改善，精神體力轉佳；飯前血糖 =二並未另加糖尿病藥)。12月2曰原有癌痛苦消失，已 y忙養豬及其它卫作。及至2_年4制癌症狀未再發 生。 ⑹N0.42,邱XX女士，乳腺癌，1954年生（48歲） 先在南σ卩某一級醫院檢驗確定為乳腺癌，並在其醫 師私設診所接受不詳治療，因病況不見改善，於2_年4、月 14曰轉於某一級軍醫院再確定，並接受内服藥醫療，院方建 議化療未成。 15In August 2001, due to the coughing sound, breathing disorder, after the original hospital test, it was found that the cancer cells metastasized to the lungs, that is, the operation was performed. Because the cancer machine was too large, it was difficult to perform surgery, so suture again. On September 14, 2001, he participated in the trial. By October 26 of the same year, the main symptoms were obviously improved. After the pain was not felt, after 4 courses of treatment, the main symptoms disappeared completely, and the medication was discontinued and continued. On February 9, 2002, the right foot bone cancer was resected, swollen and inflamed. With the drug of the present invention and a little drug, the drug was cured within two courses. -63- 1260226 .___:_ Description of invention (2), NO, 9, Ms. Zhan XX, lung cancer, born in 1942 (60 years old) Breast cancer resection in 1995; metastatic lymphatic cancer of the right supraclavicular in November 1998, after visualization A certain level of teaching hospitals to determine and apply chemotherapy and radiotherapy. In April of the next year, he was transferred to the left axilla, and was resected by the original hospital. 2〇〇1 year 5 months, re-examined and found to metastasize to lung cancer. Participated in the trial on February 1, 2001; symptoms a, panic, chest pressure, cough, chest pain. B, swelling of the abdominal abdomen, the pain in the lower abdomen. c, the right arm due to allergic reactions to radiotherapy, and lymphatic swelling, like skin swelling. D, swollen feet. 10 15 20 On March 23, 2001, the main symptoms or sputum or obvious improvement, by the original hospital test, the cancer granules no longer occur, increase, the situation is stable; to the end of the treatment, all the symptoms are more sputum, only after chemotherapy, radiotherapy The right arm is limited to a limited improvement in the skin. (3), N0.18, Ms. Chen XX, lymphoma, born in 1951 (51 years old) First, in March 1999, through a cervical cancer test in a second-level specialized hospital in Tainan, the same month π day to cut off the palace nest, radiotherapy 28 Once, continue chemotherapy once a week. The condition has not improved, but it is not effective in the treatment of tail wine therapy. I5 days after chemotherapy, full-time, right upper limbs _ _; then transferred to a second-level hospital in Kaohsiung, confirmed that it has been transferred into the lymph, bone marrow, announced that the right hand has been removed into the tranquillity ward, with scales to relieve pain, as Finally settled. , continued pain, need to wear = difficult = 2 = seven (four) (four) spoon, weakness,, seven sputum pain, in the half-course -64-1260226 - __l__I__ invention instructions, continued stomach improvement, no anesthesia, lower abdomen, two unobstructed. On September the next day, the main symptoms improved again, and there was no painful feeling. The lymphoma of the left and right bones subsided by one-half, and the right hand was active. After eating a direct selling health food, the cancer mass was swollen again, and the right arm was severely painful. The drug was used until 1 month of the 17th, the cancer was removed, the right arm was recovered, and the pain sustained by the back was completely disappeared. η Θ On the 5th, Zuo Rui's bone cancer block only contained 0.2CM, and the rest of life and living were like healthy people. It will not recur until June 2nd and 2nd. (4), Νο·23, Ms. Guo XX, lymphoma, born in 1946 (56 years old) In the first month of 1999, a certain level of teaching hospital in the south was diagnosed as bladder cancer and treated with surgery. In May 2000, it was followed. Examination, found that metastasis of rectal 1 〇 cancer, surgery, because of the reason is not removed, and the implementation of chemical infusion 5 times, soon, lymphatic cancer on the left bones, about 3.5CM, confirmed metastasis to lymphoma, and inserted into the kidney Catheter, back urine bag, the original yard. On March 1st, 2001, he participated in the trial. The main symptom a, left lymphoid lymphoma was about 3.5CM, B, lower abdominal cramps, and low back pain. c, 15 stools are urgent and heavy, and defecation is difficult. Other poor appetite, weakness, physical strength and so on. On March 21, 2001, the symptoms of B and C improved significantly. On March 28th, the lymphoma of A was gradually disappeared, but the waist and hips were sore. The main symptoms improved on April 8. On May 9th, taking direct health food (the same as the previous example) caused lymphoma to re-swell. On May 16 the main and secondary symptoms continued to improve and remained above 3 days. 20 (5), N〇·29, Mr. Wen XX, oral cancer, born in 1924 (78 years old) with diabetes, on December 16, 1998, diagnosed as oral cancer by a second-level hospital, through the original Yuan music Treatment, as well as taking a variety of drugs, the condition continues to deteriorate. Participated in the trial on October 17, 1999; the main symptoms a, oral cavity near 1260226 _i__i _ invention description, continued page B;?, left cheek, tooth silver between the appearance of cancer, under the glandular swelling, open barrier. In the case of moving silver, the cancer is swollen. C, coughing at night. Other fatigue and tiredness, physical strength is not supported, and f begins and visits. ^99 years 1M 31st, ulceration, disease improvement, collar gland swelling, cancer swelling, _ 17th day, the main symptoms improved, mental strength improved; pre-prandial blood glucose = two did not add diabetes drugs). On December 2, the original cancer pain disappeared, and it was already busy raising pigs and other guards. And the cancer form of 2 years and 4 years did not occur again. (6) N0.42, Ms. Qiu XX, breast cancer, born in 1954 (48 years old) First confirmed in a certain hospital in South 卩 为 as breast cancer, and received unspecified treatment in his doctor's private clinic, because the condition did not improve, in 2 years 4, the month 14 曰 transferred to a certain military hospital to determine, and accept internal medicine medicine, the hospital recommended that chemotherapy failed. 15

2000年4月25日起，參與本試驗；主症狀a、右乳 房内，外側呈現腫硬癌塊。乳頭微有潰瘍。其它習常便閉、 腸鳴。 、 才、On April 25, 2000, he participated in the trial; the main symptoms a, the right breast, and the outer side showed a swollen cancerous mass. The nipple has a slight ulcer. Other habits are closed and bowel sounds. , talent,

2000年5月9日第一療程内，癌腫塊已漸軟化，因樂 物通透關係，呈可接受之抽痛，5 日癌腫塊軟化、縮小、 抽痛微。6月9日乳癌腫塊按摸之消退，乳頭痊，結痂脫落。 (7)、N0.54陳XX女士，印巢癌，1962年生（4〇歲） 受試者系試驗單位他症舊患者;經高雄某二醫院縿 斷確定系左印巢癌後，即於1999年9月18日直接參與:二 驗。主症狀Α、下腹偶發脹痛、胃脘痞脹。陰部^ 有黃雜色分泌物。其它有習常便閉，小便頻等症。 -66- 1260226 r— _ 發明說明 1999年9月18日開始接受本試驗，因家庭變故關 係，不能連續用藥，至2000年5月31日，僅用藥5療程，主副 症狀基本上消失。並於2000年5月5日經原診斷醫院細掃 瞄，左卵巢瘤消退無縱跡，察其它部位亦無轉移、擴散徵象。 5 2002年5月追縱查探，猶保持健康狀態。 (8) 、NO.63,溫XX先生，骨癌，1952年生（45歲） 1996年12月，高雄某二級醫院檢驗確定，多發性骨 髓癌，謂已向上擴散三點，並發糖尿病；經射電療15次完成， 但病況卻持續惡化。 10 1997年6月3日參與本試驗;症狀A、下肢腿肌腱 消失，腿臀骨内疼痛不支，足脛腫脹，足痿，舉步難難。B、咳 嗽、咽内多痰涎。C、腹中痞脹、不舒。其它，口渴，小便頻 短，色赤，偶便閉，食欲異常，不退反增。 1997年6月15日，用藥一療程内，已可步行，疼痛減 15 至可忍受限度，足脛腫消，但腹部電療處不舒服。7月11曰， 行動已正常，咳嗽減輕。8月3日經原醫院檢測，癌細胞已告 穩定，AFP正常，糖尿AC200,8月15日，紅、白血球接近正 常。8月28日下肢腿上肌肉複生，糖尿已正常。10月9曰 原醫院再行檢測，癌細胞已被控制，無作怪能力，血球均正 20 常。 (9) 、ΝΟ·68,黃XX先生，膀胱癌，1954年生（46歲） 1999年12月，經高雄某二級大醫院檢驗確定為大 腸癌，12月18日切除，並置人工肛門。2000年3月追縱檢查， 發現轉移膀胱，經手術切開、刮除，再予縫合，不久再檢驗發 -67- I26〇226 -----^ ^ 發明說明,¾胃 現癌細胞再生。 Λ 2000年6月22日參與本試驗，主症狀Α、膀胱局 4有刺痛感覺，小便頻短。B、右下腹側疼痛。其它有食欲 不振，疲勞倦怠等副症狀。7月4日主症狀Α消失，β、改善， 但逢咳嗷則有抽搐痛。7月17日主症狀A、B均消失。 經過600天後，於2002年3月20日因他疾來診， 探知所有大腸癌，膀胱癌在此期間内未再發生症狀，且自 2000年8月開始，即已正常生活、工作。During the first course of treatment on May 9, 2000, the cancer mass gradually softened. Due to the permeability of the music, it was acceptable to cause pain. On the 5th, the cancer mass softened, shrank, and painfully. On June 9th, the breast cancer mass disappeared as it was touched, and the nipple licked and the knot collapsed. (7), N0.54 Ms. Chen XX, Yinchao Cancer, born in 1962 (4 years old) The subject is a test unit of his old patients; after a certain hospital in Kaohsiung is determined to be left-in-place cancer, Direct participation on September 18, 1999: two tests. The main symptoms are sputum, occasional pain in the lower abdomen, and stomach bloating. Pussy ^ has yellow variegated secretions. Others have regular habits, urinary frequency embolism. -66- 1260226 r- _ Description of the invention This trial was started on September 18, 1999. Due to family changes, it is not possible to continue medication. As of May 31, 2000, only 5 courses of medication were used, and the main and sub-symptoms basically disappeared. On May 5, 2000, the original diagnostic hospital was finely scanned. The left ovarian tumor disappeared without longitudinal traces, and there were no signs of metastasis or spread in other parts. 5 In May 2002, he pursued investigations and remained healthy. (8), NO.63, Mr. Wen XX, bone cancer, born in 1952 (45 years old) In December 1996, a secondary hospital in Kaohsiung examined and confirmed that multiple myeloma, which has spread up three points, and diabetes; The radiotherapy was completed 15 times, but the condition continued to deteriorate. 10 Participated in the trial on June 3, 1997; Symptom A, lower extremity leg tendon disappeared, pain in leg and hip bone was not supported, foot swelling was swollen, and it was difficult to walk. B, cough, pharynx and phlegm. C, bloating in the abdomen, uncomfortable. Others, thirst, frequent urination, color red, occasional closure, abnormal appetite, no retreat. On June 15, 1997, within one course of treatment, it was already walkable, the pain was reduced by 15 to be tolerable, and the ankle was swollen, but the abdominal electrotherapy was uncomfortable. On July 11th, the action was normal and the cough was alleviated. On August 3, the original hospital detected that the cancer cells had stabilized, AFP was normal, and diabetes was AC200. On August 15, red and white blood cells were close to normal. On August 28, the muscles in the lower limbs were reborn and the diabetes was normal. October 9 曰 The original hospital re-tested, the cancer cells have been controlled, no ability to make trouble, blood cells are 20 regular. (9), ΝΟ·68, Mr. Huang XX, bladder cancer, born in 1954 (46 years old) In December 1999, a colorectal cancer was confirmed by a second-level hospital in Kaohsiung. On December 18, the artificial anus was placed. In March 2000, the sputum examination revealed that the bladder was transferred, surgically cut, scraped, and then sutured. The test was soon performed again. -67- I26〇226 -----^ ^ Inventive Note, 3⁄4 stomach cancer cells are regenerated.参与 Participated in this trial on June 22, 2000. The main symptoms were sputum and bladder. 4 There was a stinging sensation and the frequency of urination was short. B, right lower abdomen pain. Others have sub-symptoms such as loss of appetite and fatigue. On July 4, the main symptoms disappeared, β, improved, but there was convulsions in the cough. On July 17, the main symptoms A and B disappeared. After 600 days, he was diagnosed with all the colorectal cancer on March 20, 2002. He had no symptoms of bladder cancer during this period, and since August 2000, he has been living and working normally.

-68- 1260226 坎：發明說明 (發明测驗目·翻臟;^麵纖、細麵、贿、冑脑韻_獅職明) 【發明所屬之技術領域】 本發明係有關於一種治療淋巴結關係型癌症之中藥複方。 【先前技術】 5 具有一定療效的治癌内服藥遲遲未見產銷，癌症的醫療 仍停滯在「抗癌」的泥淖裏；在存疑的抗、殺、滅前提下， 權宜性的「血管栓塞」、「放射電療」、「化學藥物滴注」等 療法，卻被誤涊為「常規」；因為它的粗淺以及忽略了病患 的整體病理，致使療效困守低限，且在繁雜、極端、剛猛 10的療私内，令患者產生煎熬、難耐的痛苦，尤其是「劑量 依賴」、惡劣的「過敏反應」、「增進轉移」等等。 由於商業利益及諸多原因的困擾，癌症的研究一直被劻 束在 疋杈式」裏，「抗癌就是治癌」的觀念廣被宣傳， 且冰植人心，而事實上，所有動聽的「理論」在未達目標 15之則’應屬於「假設」，難達目標之假設性理論，必然存在 瑕疵、疑問；故在癌症的治療研究方面，突破「一定模式」， 提出新的創見、理論、療法，實系迫切的需要，但先前提 出之創見、理論等，因缺少醫療根據，脫離了基本的、實 際的，故言雖美妙，卻是虛幻的海市蜃樓而已。 2〇 ,生物科技、癌藥研發等等專家，若無治癌的臨床經驗， 而在僅知「癌細胞」，而不知「癌環境」、「癌變化」等等繁 瑣問題，亦只能研發「抗癌藥」以對付「癌細胞」,但它與 「治癌」的實踐仍有甚遠的距離。 癌之之組織、結構、形態，以及癌位置的研究均屬重要， _次頁（發明_不_時，請_使用_ -4- 1260226 -明說明續頁 先前均以此或機體系統予以分類；但就治癌的實踐層次言 之，這種分類法並不等合治癌之目的與施展效益，須再進 一步予以「類型機理」之分類。 中國的中醫資源豐沛，近年來有關抗癌、治癌的研究頗 有進展，且不乏治癌内服藥通過國内的申請、公開發表， 但其特徵均表現在藥物與製備方式上，在闡述固有中醫治 癌的「辨證論治」外，仍然不能跳脫「抗癌即是治癌」的 窠臼；缺乏創見與新論據，且不能釋明用詞之定義，也許 因此之故，至今並不見有產業利用者。 【發明内容】 本發月的主要目的，在於提供一種治療淋巴結關係型 癌症的中藥複方，·以及與本複方發明有關的新創見、新理 論、新依據，重點在於以「變易癌環境」的新療法，颠覆 15 了「抗、殺、滅癌細胞」的舊模式，以開拓中醫藥治癌的 新途徑。 另-目的在於提供治療淋巴結關係型癌症的複方組 成' 製備方法；並採取簡易的内服療法，提高治癌有效率， 平降醫療消費，使實際利益於罹癌群眾。 20 •緣為達成本發明的上述目的，特為提供相關著作、附 件，並將本發明的創新理論、治療分類、類型機理、藥物組 配、臨床試驗以及效率統計、癌種轉移統計等，闡述如下。 【實施方式】 -5_ I260226 95. i, 26 厂、二 發明說明續頁 自上面統計所結果，足可證實此「淋巴結關係型」之 廣泛性癌種別與淋巴結、淋巴循環之間，不但關係密切， 且其功能、運作均有直接的影向；是以遵循妥善策略，選 擇適當藥物以藥物各別或組合的藥理作用，即以其物勢而 5改麦上、下腔淋巴結、淋巴循環的異常環境，促使癌細胞 產生「厭惡」感受，就是本申請案藥物組成的要件之一。 「藥物組配」 一種治療淋巴結關係型癌症的中藥複方，其系以下列 1〇經濃縮卒取之藥粉及比例所調配組成；其中1 ·之「茯苓」 為萃取賦形之粉劑，成分及含量已包含在各藥物中。 1. 茯苓 13. 黃 25. 沒 藥 2. 黨參 14. 蜃 蟲 26. 蚤 休 3. 黃芪 15. 白花蛇舌草 27. 敗 醬 4. 薏苡仁 16. "28. 白 sL 5. 山佩蘭 17. 山豆根 29. 射 幹 6. 橘皮 18. ~3〇7 蒲公英 7. 〇 爵床 19. 31. 螺 草 〇. 夏栝草 20. 32. 皂 莢 9. 涼粉草 21. — ~337 獨 活 10. 梔子 22. ~347 麻 黃 11. 連翹 23. --—- 葦 35. 升 麻 12. 赤芍 24. 乳 '~~--. 香 ——----- -13- 1260226-68- 1260226 坎:Inventive description (invention test subject · turned dirty; ^ face fiber, fine face, bribe, 胄 韵 _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ Cancer Chinese medicine compound. [Prior Art] 5 The cancer treatment with certain curative effect has not seen production and sales, and the medical treatment of cancer is still stagnant in the "anti-cancer" mud; under the premise of suspected resistance, killing and extinction, the expedient "vascular embolism" Therapies such as "radiation therapy" and "chemical drug infusion" have been mistaken for "conventional"; because of its superficiality and neglect of the overall pathology of the patient, the efficacy is low, and it is complicated and extreme. In the private treatment of the fierce 10, the patient suffers from suffering and untoldness, especially "dose-dependent", poor "allergic reactions", "enhanced transfer" and so on. Due to commercial interests and many reasons, cancer research has always been shackled in the shackles. The concept of "anti-cancer is cancer treatment" has been widely publicized, and it has ice-populated, and in fact, all the "theories" "If you do not reach the goal 15, then it should belong to the "hypothesis". The hypothetical theory of the difficult goal must be flawed and doubtful. Therefore, in the treatment research of cancer, it breaks through the "certain model" and proposes new ideas, theories, and Therapy is an urgent need, but the original ideas, theories, etc., have been separated from the basic and practical because of the lack of medical basis. However, the words are wonderful, but they are illusory mirages. 2〇, experts in biotechnology, cancer drug research and development, etc., without the clinical experience of cancer treatment, but only know the "cancer cells", do not know the "cancer environment", "cancer changes" and other cumbersome problems, can only be developed "Anticancer drugs" are used to deal with "cancer cells", but it is still far from the practice of "cancer". The organization, structure, morphology, and location of cancer are important, _ page (invention _ not _, please _ use _ -4- 1260226 - sequel to the continuation page previously classified by this or the body system However, in terms of the practice level of cancer treatment, this classification method does not wait for the purpose and effect of cancer treatment, and further needs to be classified as “type mechanism.” China’s traditional Chinese medicine resources are abundant, and in recent years, it has been related to cancer prevention. The research on cancer treatment has made progress, and there are many domestic medicines that have been applied for and approved for domestic use. However, their characteristics are manifested in the methods of medicine and preparation. In addition to the "dialectical treatment" of traditional Chinese medicine treatment, it still cannot jump. The "anti-cancer is the cure for cancer"; lack of originality and new arguments, and can not explain the definition of the word, perhaps for this reason, there is no industrial use. So the main purpose of this month It is to provide a traditional Chinese medicine compound for treating lymph node-related cancer, and new ideas, new theories and new foundations related to the invention of this compound, with a focus on the new treatment with "changeable cancer environment" Subvert 15 the old model of "anti-killing, killing, and killing cancer cells" to open up new ways to treat cancer by Chinese medicine. Another purpose is to provide a combination of 'treatment methods for treating lymph node-related cancers'; and take simple internal medicine To improve the efficiency of cancer treatment, to reduce medical consumption, and to make the actual interests of the cancer population. 20 • In order to achieve the above object of the present invention, it is necessary to provide related works and accessories, and to classify the innovative theory and treatment of the present invention. Type mechanism, drug composition, clinical trials, efficiency statistics, cancer metastasis statistics, etc. are described below. [Embodiment] -5_ I260226 95. i, 26 Factory, 2 invention description Continued from the above statistics, it is sufficient to confirm This "lymph node relationship" of extensive cancer types is not only closely related to lymph nodes and lymphatic circulation, but also has direct influence on its function and operation; it is to follow appropriate strategies to select appropriate drugs to separate or combine drugs. Pharmacological action, that is, to change the abnormal environment of the upper and lower lymph nodes and lymphatic circulation of the wheat with its physical potential, and promote the "disgust" of cancer cells. It is one of the requirements for the composition of the drug in this application. "Pharmaceutical combination" A traditional Chinese medicine compound for treating lymph node-associated cancer, which is composed of the following 1 〇 concentrated powder and proportions; "茯苓" is a powder for extracting, and its ingredients and contents are included in each drug. 1. 茯苓13. Yellow 25. Myrrh 2. Codonopsis 14. Aphid 26. 蚤休 3. Astragalus membranaceus 27. 败酱 4. 薏苡仁16. "28. 白sL 5. 山佩兰17. 山豆根29. Shooting 6. Orange peel 18. ~3〇7 Dandelion 7. 〇 床 19. 19..草〇. 夏栝草20. 32. Acacia 9. Jellyfish 21. — ~337 独活10. 栀子22. ~347 麻黄11. Forsythia 23.. ——— 苇35. Cimicifuga 12. Akasaka 24. Milk '~~--. Fragrance——----- -13- 1260226

上述各藥物中，茯苓為萃取賦形之粉劑（含量為 9.85%) ’其他各藥物之配比為ι·94%_3 94%，並可依癌患 體病理之微異而取捨藥物或酌以增減其比例，其最佳配比 5為各藥物之配比均為2.94%，共計100%。 「藥理說明」 各藥物條下的藥理說明，系以改善「周環病理」之三 項病象，亦即「增進胰腺功能，及與各器官的連系」，「排 10除門靜脈、肝、脾内的通透障礙，平降門脈壓」，「改善防 7Κ功肖b、淋巴循環、提高免疫力」三大重點；以及「通透 淋巴結、及其它必要作用」、等四項藥理而分類。但中藥多 存在複性的藥理，而非單一，有包羅上列數種作用者，故 僅以權宜配置’再於（藥物說明資料表）中另加以敘述。 15 一、增進胰腺功能及與各器官的聯繫： ―、茯苓一補充營養、促進胰腺功能、增強免疫功能、安 定神經系統、調整心律及機體的水分代謝。現代藥理，增 強正常及荷瘤小鼠的免疫功能，提高巨噬細胞的吞噬能 力，對鼻咽癌、胃癌、宮頸癌等多種癌症有正面效益。在 2〇本^列治癌發明中，以之代替舊有玉米、小麥等殿粉「賦 形藥」，凡各種濃縮萃取之藥液，除部分以原藥未收搜、乾 燥外，其餘均用純茯茶未收攪賦形，以增強治癌效力。 #黨參-補充營養、增進胰腺、肺臟功能，改善腺體素 貝與刀^必。現代藥理試驗證實，有增強機體應激能力、免 -14- 1260226Among the above-mentioned drugs, strontium is a powder for extracting and shaping (content is 9.85%). The ratio of other drugs is ι·94% _3 94%, and the drug may be selected according to the pathological difference of the cancer patient or Increase or decrease the proportion, the best ratio of 5 for each drug ratio is 2.94%, a total of 100%. "Pharmacological Description" The pharmacological description under each drug strip is to improve the three symptoms of "circumferential pathology", that is, "improve pancreatic function and connect with various organs", "discharge 10 except portal vein, liver, Impedimental dysfunction in the spleen, flattening the portal pressure, "improving the prevention of sputum, lymphatic circulation, and improving immunity"; and "transparent lymph nodes, and other necessary effects", and other four pharmacological effects classification. However, there are many remedies for traditional Chinese medicine, rather than a single one. There are several kinds of actors listed above, so they should be configured only by expediency and then described in the drug description data sheet. 15 I. Enhance pancreatic function and contact with various organs: ―, 茯苓 补充 supplement nutrition, promote pancreatic function, enhance immune function, stabilize nervous system, adjust heart rhythm and body water metabolism. Modern pharmacology enhances the immune function of normal and tumor-bearing mice, enhances the phagocytic capacity of macrophages, and has positive effects on various cancers such as nasopharyngeal carcinoma, gastric cancer, and cervical cancer. In the 2 〇 ^ 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治 治Pure tea is not harvested to enhance the efficacy of cancer treatment. #党参-Supply nutrition, improve pancreas and lung function, improve glandularity and shellfish and knife. Modern pharmacological tests have confirmed that there is an increase in the body's ability to stress, free of -14-1260226

95, U 7攀明說明續頁 「藥物說明資料表 NO: 1 中草藥名稱 茯茶Fuling 學名Poria cocoa(schw.)WOLF. 依 據 中藥大辭典第1596頁，中華本草第1冊第 554頁（中國上海科學技術出版社） 產地、採收季節、部位 湖北、安徽產。栽種8〜10個月成熟，扒開 視察菌核表皮呈要褐色，即可收穫，選晴 天挖出，去泥砂，堆在室内蓋稻草使發汗 (水分），等苓皮起皺削去外皮，乾燥。 炮製、萃取過程、方法 (1) 選體重、堅實，外皮棕褐、皮紋細、無 裂隙、斷面白色細腻、粘牙力強者，削 去表皮，浸軟、切薄片，乾燥。 (2) 50kg粉碎，過120目篩為幼末收存。 有 效成分 菌核含/3 -茯荟聚糖（冷-Pachyman)約占幹重 93%，和三結類化合物乙酰茯苓酸 (Pachymicacid)，3冷-經基羊毛甾三烯酸[3 /3 -Hydroxylanosta_7.9(ll)，24-trien-21-oilacid]4b 外，尚含樹膠，甲壳質，脂肪，甾醇，卵磷脂， 葡萄糖，腺嘌呤，組氨酸，膽碱，/3茯苓聚糖分 解酶，脂肪酶，蛋白酶等。另外還含有0.23%的 無機元素(Ash)，包括鐵、舞、鎂、钟、納、錦、 磷等。 原記載藥理作用 補充營養，促進胰腺功能及免疫功能，安 定神經系統，調整心律。增進機體水分代 謝，利尿。 現代藥理，增強正常及荷瘤小鼠的免疫功 能，提高巨噬細胞的吞噬能力：對鼻咽癌、 胃癌、宮頸癌等多種癌症有正面效益。 藥理應用、目的 補充營養，促進胰腺功能，免疫能力、水 分代謝。在本發明中，主要用作「賦形藥」， 凡各種濃縮萃取藥液，除部份以原藥未收 攪、乾燥外，其餘均用純茯苓未收攪賦形， 用以代替一般使用之玉米、小麥等食用澱 粉。 -21- 1260226 蠢明說明續頁 NO: 3 中草藥名稱 黃芪 學名Astragalus Huanggi membranaceus 依 據 中藥大辭典第2036頁，中華本草第4冊第 341頁（中國上海科學技術出版社） 產地、採收季節、部位 主產於山西、内蒙古，秋季深刨採挖根部， 切去蘆頭，抖淨泥土，曬半幹，堆積2日，再曰 曬至全幹，整形、紮成小捆。 炮製、萃取過程、方法 (1) 黃芪6kg，洗淨，浸軟切片，入鍋水浸3h， 加熱分二次煎取藥液。 (2) 加熱揮發水分，剩3公升濃液時，入1kg 苓粉攪勻。 (3) 65°C 乾燥。 (4) 粉碎過100目篩為末，密封收貯。 有 效成分 含黃笑戒(astragaloside) I、II、IV、大豆皂武 (soyasaponin) I，毛蕊異黃酮-7-0- ^ -D-葡萄糖甙 (calycosin-7-O-冷-D-glucoside)等多種武、_、 酚、酯、多糖的成分，均具有增強免疫功能的作 用。並含近二十多種微量元素，其中鈣、磷、鎂、 鐵等含量較高。 原記載藥理作用 補充營養、微量元素、增強體力、增進淋 巴導管上升動能；調節自律神經，防止汗腺 異常過敏。利尿，調節機體水分代謝，改善淋 巴體質，補充防禦細胞養分。現代藥理研究 證實，對免疫系統有良性影向，對機體代 謝、心血管系統有幫助；並有抗病毒、抗癌 的作用。 藥理應用、目的 調整胰腺功能，改善淋巴體質，補充防禦細 胞所需養分。，增進淋巴導管上升動能;連系 器官關係。 -23- 1260226 95. t. 26 發明說明*Η NO: 6 中草藥名稱 橘皮（陳皮）學名Citrus reticulata chenpi 依 據 中藥大辭典第2637頁，中華本草第4冊第 886頁（中國上海科學技術出版社） 產地、採收季節、部位 為福建，江西產朱橘或福橘的果皮，先行風 乾、再曬乾貯存於乾燥、陰涼處。 炮製、萃取過程、方法 (1) 幹陳皮4kg，淡鹽水洗浸，切成條狀，浸 入健康人尿中24h;取出洗淨，置於清潔 流動水中漂浸24h以上，使去腥昊氣 味；以姜汁、純米、醋、食鹽水分別炒 過，再乾燥，並以1kg研末。 (2) 3kg入鍋水浸3h，分二次煎取藥液。 (3) 加熱揮發水分，剩3公升濃液，入藥末 攪勻。 (4) 45°C 乾燥。 (5) 粉碎，過120目篩為幼末，密封收貯。 有 效成分 原橘皮含揮發油1.2%-3.19%，主成分為檸 檬稀（limonene)，及其它稀、酸、醇等成分， 又含黃麵I類成分，撥皮甙，曱米橘素。還含冷 -穀留醇，擰檬苦素，阿魏酸等，經尿，醋，薑，鹽 浸炒後藥性變為緩和，並增強它在人體内 之浸透性。 原記載藥理作用 緩和上消化道神經過敏，矯味開胃、增進食 欲，促進消化道器官水分代謝，祛除組織内 稠粘物質。通導賁口、幽門神經；緩和氣 管、支氣管過敏。 藥理應用、目的 促進組織液'、淋巴液、水分的新陳代謝， 預防血液稠粘度的形成，調整胰、胃、腸的 功能，改變癌環境。 -26- 1260226 發明說明 NO: 8 中草藥名稱 夏枯草 學名 Prunella Vulgaris L. xiakucao 依 據 中藥大辭典第1827頁，中華本草第冊第 頁（中國上海科學技術出版社） 產地、採收季節、部位 江蘇、河南、安徽產。5〜6月花穗變成棕 褐色時，割起全草，捆成小把,曬乾。 炮製、萃取過程、方法 (1) 6kg洗淨，切小段，入锅水浸3h，加熱分 二次煎取藥液。 (2) 加熱揮發水分，剩3公升黑色濃液，入茯 苓粉1kg攪勻。 (3) 65°C 乾燥。 (4) 粉碎，過120目篩為幼末收貯。 有 效成分 全草含三萜皂甙，其甙元是齊墩果酸 (oleanolicacid)，尚含遊離的齊墩果酸，熊果 酸（ursolic acid)，芸香武（rutin)，金絲桃武 (hyperoside)，川頁一咖 口非酸（caffelcacid)，反一 咖啡酸，維生素B1，維生素C，維生素K，胡蘿 蔔素，樹脂，苦味質，揮發油，生物碱，水溶性 鹽類（約3·5%，其中約68%是氯化鉀）等。花 穗含飛燕草素（delphinidin)和矢車菊素 (cyanidin)的花色武，d-樟腦（d-camphor) d-小茴香酮（d-fenchone)，熊果酸。 原記載藥理作用 改善眼睛周環血液循環，清除肝血竇障礙， 通透肝循環，調降門脈壓。通透淋巴腺，消除 淋巴結的發炎、腫硬。現代藥理，有顯著的 降血壓作用，臨床研究治療黃疸型肝炎、肺 結核有效。 藥理應用、目的 清除肝循環障礙，改善淋巴，尤其是肝内微 ***的代謝，協同他藥排除肝循環、肝血 竇、門靜脈管壁的有害異質。調降血壓、 門靜脈壓皆出於夏枯草通透、清除、解毒 的藥理。 -28 - 1260226 95. i. 26 厂--- 發明說明m NO: 9 中草藥名稱 涼粉草 學名Mesona chinensis liangfencao benth 依 據 中藥大辭典第1915頁，中華本草第7冊 第87頁（中國上海科學技術出版社） 產地、採收季節、部位 福建、臺灣產。夏季收割地上部分，曬至半 幹，推疊使之發酵、變黑，再曬至足幹，收捆 成束。 炮製、萃取過程、方法 (1) 6kg，洗，切，其1kg日曬研末，另5kg入鍋 水浸8h，加熱分二次煎取藥液。 (2) 加熱揮發水分，剩3公升濃液，候冷入藥 末攪勻。 (3) 45°C 乾燥。 (4) 粉碎過120目篩為幼末收貯。 有 效成分 全草含涼粉草多糖（MCPS，mesona chinensis benth polysaccharide)，相對分子 質量為43000,水解得葡蔔糖(glucose)，半乳 糖（glactose)，***糖（arabinose)，木糖 (xylose)，鼠李糖（rhamnose)和半乳糖酸酸 (galacturonic acid)，及一種未知糖。 原記載藥理作用 能增加血液中陰柔元素，解除因天氣暑熱 引起的人體不良影向，清除機體激進成分， 而有解毒、解渴、清涼消炎的功效。可治 療高血壓、糖尿病、民間用治性病感染的 骨内疼痛。 藥理應用、目的 解熱毒，消炎，平降門脈壓，改變癌環境的偏 高溫度，排除有害毒素。 -29- 1260226 ‘日95, U 7 Pan Ming Instructions Continued page "Drug Description Data Sheet NO: 1 Chinese herbal medicine name Fuling Fuling scientific name Poria cocoa (schw.) WOLF. According to Chinese Medicine Dictionary 1596, Chinese Materia Medica No. 1 (page 554 (Shanghai Science, China) Technology Press) Origin, harvest season, location Hubei, Anhui production. Planting 8~10 months mature, open the inspected sclerotial epidermis to be brown, you can harvest, choose sunny to dig out, go to mud sand, pile in the indoor cover The straw makes sweating (moisture), and the suede is creased and peeled off, and dried. Processing, extraction process, method (1) Weight selection, solid, brown skin, fine skin, no cracks, white and delicate cross section, sticky For strong teeth, cut off the epidermis, macerate, cut into thin slices, and dry. (2) 50kg crushed, 120 mesh sieve for younger storage. Active ingredient sclerotia contains /3 - 茯-polysaccharide (cold-Pachyman) 93% by dry weight, and the trivalent compound acetyl phthalic acid (Pachymic acid), 3 cold-based lanolinone [3 /3 -Hydroxylanosta_7.9(ll), 24-trien-21-oilacid]4b , still contains gum, chitin, fat, sterol, lecithin, glucose, adenine , histidine, choline, / 3 茯苓 glycolytic enzymes, lipase, protease, etc. Also contains 0.23% of inorganic elements (Ash), including iron, dance, magnesium, bell, nano, brocade, phosphorus and so on. Originally recorded pharmacological effects to supplement nutrition, promote pancreatic function and immune function, stabilize nervous system, adjust heart rhythm, increase body water metabolism, diuretic. Modern pharmacology, enhance the immune function of normal and tumor-bearing mice, and improve the phagocytic ability of macrophages: It has positive effects on various cancers such as nasopharyngeal carcinoma, gastric cancer, cervical cancer, etc. Pharmacological application, purpose to supplement nutrition, promote pancreatic function, immunity, and water metabolism. In the present invention, it is mainly used as a "formation medicine", where various kinds of enrichment The extracting liquid is used to replace the edible starch such as corn and wheat which are generally used, except that some of the original medicine is not stirred and dried. -21- 1260226 Stupid description continuation page NO: 3 Chinese herbal medicine name Astragalus Huanggi membranaceus According to Chinese medicine dictionary, page 2036, Chinese herbal medicine, Book 4, page 341 (Shanghai Science and Technology Press, China) Origin, harvest season, location Mainly produced in Shanxi, Inner Mongolia, deep planing in the autumn to dig the roots, cut off the head, shake the soil, dry and dry, piled up for 2 days, then simmer until the whole dry, plastic, tied into small bundles. Processing, extraction process, method (1) Astragalus 6kg, washed, soaked in soft slices, immersed in a pot for 3h, heated to separate the liquid. (2) Heat the volatile water. When 3 liters of concentrated solution is left, mix 1kg of glutinous powder and mix well. (3) Dry at 65 °C. (4) Smash the 100 mesh sieve to the end, seal and store. The active ingredients include astragaloside I, II, IV, soyasaponin I, and isoflavones 7-0- ^ -D-glucoside (calycosin-7-O-cold-D-glucoside ) A variety of components such as wu, _, phenol, ester, and polysaccharide all have the function of enhancing immune function. It contains nearly twenty kinds of trace elements, among which calcium, phosphorus, magnesium and iron are high. Originally recorded pharmacological effects to supplement nutrients, trace elements, enhance physical strength, increase the kinetic energy of lymphatic catheter; regulate autonomic nerves, prevent abnormal allergic sweat glands. Diuretic, regulate the body's water metabolism, improve the body's physique, and supplement the defense cell nutrients. Modern pharmacological research has confirmed that it has a benign influence on the immune system, which is helpful to the body's metabolism and cardiovascular system; and has antiviral and anticancer effects. Pharmacological application, purpose To adjust the function of the pancreas, improve the lymphatic quality, and supplement the nutrients needed to protect the cells. Increase the kinetic energy of lymphatic vessels; connect organs. -23- 1260226 95. t. 26 Description of invention *Η NO: 6 Chinese herbal name Orange peel (Chen's peel) Scientific name Citrus reticulata chenpi According to the Chinese Medicine Dictionary 2637, Chinese Materia Medica No. 4, page 886 (Shanghai Science and Technology Press, China) The place of origin, harvest season, and parts are Fujian, the fruit of Jiangxi orange or Fu orange, dried first, then dried and stored in a dry, cool place. Processing, extraction process, method (1) 4kg of dried tangerine peel, washed with light salt water, cut into strips, immersed in the urine of healthy people for 24h; taken out and washed, placed in clean flowing water for more than 24h, so that the smell is deodorized; Stir-fry with ginger juice, pure rice, vinegar and salt water, then dry and add 1kg of powder. (2) 3kg into the pot for 3h, and take the liquid twice. (3) Heat the volatile water, leaving 3 liters of concentrated solution, and mix well at the end of the drug. (4) Dry at 45 °C. (5) Crush, pass through a 120 mesh sieve for the young, sealed and stored. Effective ingredients The original orange peel contains 1.2%-3.19% of volatile oil. The main component is limenene, and other components such as dilute, acid and alcohol. It also contains yellow-faced I-class ingredients, scalp and glutinous rice. It also contains cold-column alcohol, sulphuric acid, ferulic acid, etc., after urinary, vinegar, ginger, and salt, the medicinal properties become mild and enhance its permeability in the human body. Originally recorded pharmacological effects to alleviate upper gastrointestinal nervous system, taste appetizing, increase appetite, promote water metabolism in the digestive tract organs, and remove sticky substances in tissues. Guide the fistula, pyloric nerve; relieve tracheal and bronchial allergy. Pharmacological application, purpose To promote the metabolism of tissue fluids, lymph, and water, prevent the formation of thick blood viscosity, adjust the functions of pancreas, stomach, and intestines, and change the cancer environment. -26- 1260226 Description of invention NO: 8 Chinese herbal medicine name Prunella Vulgaris L. xiakucao According to the Chinese Dictionary of Chinese Medicine, page 1827, Chinese herbal medicine, the first page (Shanghai Science and Technology Press, China) Origin, harvest season, location Jiangsu, Henan, Anhui production. When the spikes become brownish brown from May to June, the whole grass is cut, bundled into small pieces, and dried. Processing, extraction process, method (1) Wash 6kg, cut into small sections, dip in the pot for 3h, and heat to separate the liquid. (2) Heat the volatile water, leaving 3 liters of black dope, and mix well with 1 1 powder 1kg. (3) Dry at 65 °C. (4) Crushing, passing through a 120 mesh sieve for storage at the end of the baby. The active ingredient whole grass contains triterpenoid saponin, its anthraquinone is oleanolic acid, which also contains free oleanolic acid, ursolic acid, rutin, hyperoside. ), Chuan page, a non-acid (caffelcacid), anti-caffeic acid, vitamin B1, vitamin C, vitamin K, carotene, resin, bitter taste, volatile oil, alkaloids, water-soluble salts (about 3.5%) , about 68% of which is potassium chloride) and the like. The flower spike contains delphinidin and cyanidin, d-camphor d-fenchone, ursolic acid. Originally recorded pharmacological effects to improve blood circulation around the eye, clear hepatic sinus disorders, penetrate the liver circulation, reduce portal pressure. It penetrates the lymph glands and eliminates the inflammation and swelling of the lymph nodes. Modern pharmacology has a significant blood pressure lowering effect, and clinical research is effective in treating jaundice hepatitis and tuberculosis. Pharmacological application, purpose To clear the liver circulation disorder, improve the metabolism of lymph, especially the intrahepatic micro-lymphatic vessels, and cooperate with other drugs to eliminate the harmful heterogeneity of the liver circulation, hepatic sinus and portal vein wall. Lowering blood pressure and portal pressure are all based on the pharmacology of Prunella vulgaris, clearing and detoxification. -28 - 1260226 95. i. 26 Factory--- Description of invention m NO: 9 Chinese herbal medicine name Cool grass name Mesona chinensis liangfencao benth According to Chinese Medicine Dictionary No. 1915, Chinese Materia Medica No. 7 (page 87) (Shanghai Science and Technology Publishing, China)社) Origin, harvest season, location Fujian, Taiwan. In the summer, harvest the upper part of the ground, dry it to a semi-dry, push it to ferment it, turn it black, then dry it to the foot and bundle it into bundles. Processing, extraction process, method (1) 6kg, wash, cut, 1kg sun drying, another 5kg into the pot, immersed for 8h, heated to sub-duce the liquid. (2) Heat the volatile water, leaving 3 liters of concentrated liquid, and mix it with cold at the end of the medicine. (3) Dry at 45 °C. (4) Smashed through a 120 mesh sieve for storage at a young age. The active ingredient whole grass contains MPS, mesona chinensis benth polysaccharide, with a relative molecular mass of 43,000, which is hydrolyzed to obtain glucose, glactose, arabinose, xylose. Rhamnose and galacturonic acid, and an unknown sugar. The original recorded pharmacological effects can increase the feminine elements in the blood, relieve the adverse effects of the human body caused by the heat of the weather, remove the radical components of the body, and have the effects of detoxification, quenching thirst, cooling and reducing inflammation. It can treat intra-abdominal pain caused by hypertension, diabetes, and private use of sexually transmitted diseases. Pharmacological application, purpose Antipyretic, anti-inflammatory, flattening portal pressure, changing the high temperature of the cancer environment, and eliminating harmful toxins. -29- 1260226 ‘Day

捕无 m明續頁 NO: 13 中草藥名稱 大黃 學名 Rheum officinale Dahuang 依 據 中藥大辭典第102頁，中華本草第2冊第 708頁（中國上海科學技術出版社） 產地、採收季節、部位 四川產。取根及根莖，刮去外皮、整形、室 内陰乾四分，再以火烘乾。 炮製、萃取過程、方法 (1) 大黃4kg，洗浸切片，1kg烘乾研末，另 3kg入锅水浸8h，加熱分二次煎取藥 液。 (2) 加熱揮發水分，剩3分升濃液，入藥未檟: 勻。 (3) 65°C 乾燥。 (4) 粉碎過120目篩為幼末，收貯。 有 效成分 含總蒽醌量2.034%-2.984%，其中游離蒽醌 合量為0.037%-1.155%，結合蒽醌含量為 1.829%-1.997%。還含掌葉大黃二蒽酮 (palmldin)A、B、C等四種雙蒽酮類成分。 又含二苯乙烯甙類成分。苯丁酮類成分。 又含樹脂以及右旋兒茶精（catechin)，左旋 表兒茶精沒食子酸脂（epicatechin gallate)、葡萄糖沒食子鞣甙（glucogallin) 等。 原記載藥理作用 原記載與現代藥理研究之結果頗相吻合， 在消化系統中，有保肝、利膽、抗胃及十二 指腸潰瘍；阻止結腸内水分吸收、加快内容 物排出而有導瀉作用。有抗菌、抗病毒、 抗真菌作用。以及抗炎、止血、降低血清 總膽固醇等效能。 ，藥理應用、目的 保肝、利膽、抗病毒，疏導，排除體内有害物 質。 -33- 1260226 95. » 2^ ；. ，丨 ί..*The name of the Chinese herbal medicine Rheum officinale Dahuang is based on the Chinese Medicine Dictionary 102, Chinese Materia Medica Volume 2, page 708 (Shanghai Science and Technology Press, China) Origin, harvest season, location Sichuan . Take the roots and rhizomes, scrape off the skin, plasticize, and dry in the room for four minutes, then dry with fire. Processing, extraction process, method (1) Rhubarb 4kg, washing and immersing slices, 1kg drying and grinding, another 3kg into the pot for 8h, heating and sub-frying the liquid. (2) Heat the volatile water, leaving 3 minutes of concentrated liquid, and the medicine is not smashed: evenly. (3) Dry at 65 °C. (4) Smash the 120 mesh sieve into a young one and store it. The effective ingredient contains 2.034%-2.984% of total sputum, wherein the free chelating amount is 0.037%-1.155%, and the combined strontium content is 1.829%-1.997%. It also contains four diterpene ketones such as palmldin A, B, and C. It also contains a stilbene quinone component. Benzanone-based ingredients. It also contains resin and catechin, ecticchin gallate, glucogallin, and the like. Originally recorded pharmacological effects The original records are quite consistent with the results of modern pharmacological research. In the digestive system, there are liver protection, choleretic, anti-gastric and duodenal ulcers; prevention of water absorption in the colon and accelerated discharge of contents have a cathartic effect. It has antibacterial, antiviral and antifungal effects. And anti-inflammatory, hemostasis, and lower serum total cholesterol equivalent energy. , pharmacological application, purpose to protect the liver, choler, anti-virus, grooming, eliminate harmful substances in the body. -33- 1260226 95. » 2^ ;. ,丨 ί..*

NO: 14 中草藥名稱 番蟲學名 Eupolyphaga sinensis Zhechong walker 依 據 中藥大辭典第2684頁，中華本草第9冊 第151頁（中國上海科學技術出版社） 產地、採收季節、部位 河南產。捕捉後，用沸水烫死,曬乾。 炮製、萃取過程、方法 (1) 蜃蟲4kg，18度米酒浸洗，慢火炒幹，使 呈微黃色，1kg研成細末，另3kg入鍋水 浸3h，加熱分二次煎取藥液。 (2) 加熱蒸發水分，使剩2升升濃液;入藥 未攪:勻。 (3) 60°C 乾燥。 (4) 粉碎過120目篩為幼末收存。 有 效成分 含多種脂肪酸（fatty acid)，還含谷氨酸 (glutamic acid)等17等氨基酸，又含具有血 纖維蛋白溶酶原啟動物樣成分，並含生物 石咸以及膽甾醇（cholesterol)等醇類，另有 鉀、鎂、鈣、鋅、磷等28種無機元素，尿 密口定(uracil)，尿囊素（allantoin)。 原記載藥理作用 抗凝血，解除血管中血栓，對腱梢筋膜損傷 及骨折複元有一定助益。現代藥理：具有直 接擴張血管作用，抗凝血、延緩動脈粥樣 硬化的形成 藥理應用、目的 疏通小動脈、微血管之血液循環，緩解其間 血检。配合他藥於微循環中帶出敗亡癌細 胞或有害物質。 -34- 1260226 鲞明說明續頁 NO: 15 中草藥名稱 白花蛇舌草 Bai huashe -shecao 學名 Hedyotis diffusa (wild) roxb 依 據 中藥大辭典第754頁，中華本草第6冊第 433頁（中國上海科學技術出版社） 產地、採收季節、部位 產於安徽、廣西及東南沿海各省。夏秋季 採收全草，洗淨、曬乾，貯於陰涼乾燥處。 炮製、萃取過程、方法 (1) 白花蛇舌草6kg，入鍋水浸3h，加熱分二 次煎取藥液。 (2) 加熱揮發水分，剩3公升黑色濃液，入 1kg茯苓粉攪勻。 (3) 65°C 乾燥。 (4) 粉碎過120目篩為細末收貯。 有 效成分 全草含車葉草甙(asperuloside)，車葉草甙酸 (asperulosidic acid)，去乙酿基車葉草武酸 (deacetylasperulosidic acid)，多種雞屎藤次 甙，甲脂蒽S昆類等，以及熊果酸(ursolic acid) 酸，/5 -穀错醇（占-sitosterol)，三十一烧，豆 甾醇，齊墩果酸，對-香豆酸。 原記載藥理作用 清除激進元素引發的偏高溫度，解毒；促進 局部組織、尤其是下腹腔内器官的水分代 謝。現代藥理試驗，有增強白細胞吞噬能力， 提高免疫功能，以及抗菌、抗腫瘤的作用。 對於胃癌、直腸癌有一定的療效。 藥理應用、目的 清除激進元素，有毒物質；促進水分代謝與 血液、淋巴循環。據應用經驗，對於小腸集 結淋巴球（培氏斑）、腸骨淋巴結的功能促 進，有顯著作用。 -35- 1260226 95. i 26 發明說明 NO: 22 中草藥名稱 漏蘆 學名 Rhaponticum uniflorum loulu 依 據 中藥大辭典第2576頁，中華本草第7冊第 976頁（中國上海科學技術出版社） 產地、採收季節、部位 山東，河南，臺灣（阿里山）產。秋後採收，除去 泥土，葉莖殘基，取地下根莖曬乾。 炮製、萃取過程、方法 (1) 6KG浸幹、切片，1KG曬，研為末，另5KG 入鍋水浸3H，加熱分二次煎取藥液。 (2) 加熱揮發水分，剩3公升時入原藥末 1KG攪勻。 (3) 45°C 乾燥。 (4) 粉碎過100目篩為末收貯。 有 效成分 根含擰檬稀(limonene)、薄荷酮(menthone) 等24種揮發油成分。又含地榆糖甙 (ziyugluooside)，l，蒲公英賽醇乙酸酯 (taraxerol acetate)，熊果酸（ursonicacid)，三 十烧酸（triacontanoic acid)，/5 -穀甾醇（/3 -sitosterol)，胡蘿蔔戒（daucosterol)。 原記載藥理作用 促進血液循環，以及產婦乳汁分泌，降低機 體偏高溫度，增進防禦系統解毒功能。現代 藥理研究證實，有抗動脈粥樣硬化、抗氧 化、保肝、提高免疫功能等作用。 藥理應用、目的 經發明人研究，實驗發覺，多數促進產婦乳 汁分泌的藥物，同時有促進淋巴循環的效 能。本藥物即為其中之例，觀其主治,瘡癤腫 毒、乳腺炎、淋巴結核、痹瘻等症,均與淋 巴結有關。通透培氏斑、腸骨淋巴結、鼠 蹊淋巴結，以達促進腎臟、下腹腔内淋巴通 透是主要的藥理目的。 -42- 1260226 發明說明 NO: 26 中草藥名稱 蚤休 學名 Paris polyphylla zao xiu 依 據 中藥大辭典第1748頁，中華本草第8冊第 130頁（中國上海科學技術出版社） 產地、採收季節、部位 福建，臺灣產，在9-10月秋季曲葉枯倒時，挖 起根莖，曬乾或烘乾後，撞去粗皮，鬚根。 炮製、萃取過程、方法 (1) 華重樓品種的蚤休4KG，洗淨，切 片，1KG烘乾研末，另3KG入鍋加水浸 3H，加熱分二次煎取藥液。 (2) 加熱揮發水分，剩3公升入藥末攪勻。 (3) 65°C 乾燥。 (4) 粉碎過120目篩為幼末收貯。 有 效成分 根莖含薯蕷皂甙元-3-0- a _L-吱喃*** 糖基（1+4)-[ α-L-呲喃鼠李糖基（1+2)]-冷-D- °此喃葡萄糖甙{diosgenin-3-o- α -L-arabinofuranosyl(l->4)-[ a -L-rhamnopyranosyl(l —2)]}- β -D-glucopyranoside}，以及多種息式元，糖基，糖 戒等成分。 原記載藥理作用 鎮靜神經，疏通淋巴器官及防禦組織，排除 其間異質，消除器官，組織，肝臟内的發炎現 象。 藥理應用、目的 疏通淋巴器官及防禦組織，排除其間異質。 -46-NO: 14 Chinese herbal medicine name The name of the genus Eupolyphaga sinensis Zhechong walker According to the Chinese Pharmacy Dictionary 2684, Chinese Materia Medica No. 9 (page 151 (China Shanghai Science and Technology Press) Origin, harvest season, location Henan. After being caught, it is boiled with boiling water and dried. Processing, extraction process, method (1) 4kg of locusts, 18-degree rice wine dipping, slow-fired and frying, making it slightly yellow, 1kg is ground into fine powder, another 3kg is immersed in the pot for 3h, heating is divided into two times to take the liquid . (2) Evaporate the water by heating, so that 2 liters of the concentrated liquid is left; the medicine is not stirred: evenly. (3) Dry at 60 °C. (4) Smashed 120 mesh sieve for storage in young. The active ingredient contains a variety of fatty acids, and also contains 17 amino acids such as glutamic acid, and contains plasminogen-like promoter-like components, including bio-salt and cholesterol. Alcohols, there are 28 kinds of inorganic elements such as potassium, magnesium, calcium, zinc and phosphorus, uracil and allantoin. The original description of pharmacological effects of anticoagulation, the relief of blood vessel thrombosis, the fascia fascia injury and fracture recovery have certain benefits. Modern pharmacology: It has the function of directly expanding blood vessels, anticoagulation, and delaying the formation of atherosclerosis. Pharmacological application, purpose To clear the blood circulation of small arteries and microvessels, and relieve blood test. Combine with other drugs to bring out dead cancer cells or harmful substances in the microcirculation. -34- 1260226 鲞明说明, continuation page NO: 15 Chinese herbal medicine name Hedyotis diffusa Bai huashe -shecao Scientific name Hedyotis diffusa (wild) roxb According to the Chinese Dictionary of Chinese Medicine, page 754, Chinese herbal medicine, Volume 6, page 433 (Shanghai Science and Technology, China) Publishers) Origin, harvest season, and parts are produced in Anhui, Guangxi and southeast coastal provinces. Harvest all the grass in summer and autumn, wash, dry and store in a cool dry place. Processing, extraction process, method (1) 6 kg of Hedyotis diffusa, immersed in a pot for 3 h, and heated to take the liquid twice. (2) Heat the volatile water, leaving 3 liters of black concentrated solution, and mix well with 1kg of glutinous rice. (3) Dry at 65 °C. (4) The 120 mesh sieve is pulverized for fine storage. The active ingredient whole grass contains asperuloside, asperulosidic acid, deacetylasperulosidic acid, a variety of chicken vines, and scorpion scorpion S. And ursolic acid, /5-salcohol (sitosterol), thirty-one, soy, olean, p-coumaric acid. Originally documented pharmacological action to remove the high temperature caused by radical elements, detoxification; promote the water metabolism of local tissues, especially in the lower abdominal cavity. Modern pharmacological tests have the ability to enhance leukocyte phagocytosis, improve immune function, and antibacterial and antitumor effects. It has a certain effect on gastric cancer and rectal cancer. Pharmacological application, purpose to remove radical elements, toxic substances; promote water metabolism and blood, lymph circulation. According to the application experience, it has a significant effect on the function of the small intestine collecting lymphocytes (Pei's plaque) and intestinal lymph nodes. -35- 1260226 95. i 26 Description of invention NO: 22 Name of Chinese herbal medicine Rhodoticum uniflorum loulu According to Chinese Medicine Dictionary 2576, Chinese Materia Medica No. 7 (page 976 (Shanghai Science and Technology Press, China) Origin, harvest season , Shandong, Henan, Taiwan (Alishan) production. Harvested after the fall, remove the soil, the stem residue of the leaves, and take the roots and stems to dry. Processing, extraction process, method (1) 6KG dipping, slicing, 1KG drying, grinding for the end, another 5KG into the pot water immersion 3H, heating to sub-duce the liquid. (2) Heat the volatile water, and when it is 3 liters, put it into the original drug 1KG and mix well. (3) Dry at 45 °C. (4) Smashed through a 100 mesh sieve for final storage. Effective ingredients The root contains 24 volatile oil components such as limonene and menthone. Also contains ziyugluooside, l, taraxerol acetate, ursonic acid, triacontanoic acid, /5-sitosterol , carrot ring (daucosterol). The original recorded pharmacological effects promote blood circulation, as well as maternal milk secretion, reduce the body's high temperature, and enhance the detoxification function of the defense system. Modern pharmacological studies have confirmed that it has anti-atherosclerosis, anti-oxidation, liver protection, and immune function enhancement. Pharmacological application and purpose According to the research of the inventors, it has been found that most of the drugs that promote the secretion of maternal milk have the effect of promoting lymphatic circulation. This drug is one of them, and its main indications, such as swollen carbuncle, mastitis, lymphatic tuberculosis, and sputum, are all related to lymph node. It is the main pharmacological purpose to penetrate Peyer's patches, intestinal lymph nodes, and murine lymph nodes to promote lymphatic permeation in the kidney and lower abdomen. -42- 1260226 Description of invention NO: 26 Chinese herbal medicine name 蚤休学名 Paris polyphylla zao xiu According to the Chinese Medicine Dictionary 1748, Chinese Materia Medica No. 8 (page 130) (Shanghai Science and Technology Press, China) Origin, harvest season, location Fujian Produced in Taiwan, when the autumn leaves fall in the autumn of September-October, the roots are dug up, dried or dried, and the rough skin and the roots are hit. Processing, extraction process, method (1) Huakun Building variety of 蚤 4KG, washed, sliced, 1KG drying and grinding, and another 3KG into the pot with water immersion 3H, heating and secondary decoction liquid. (2) Heat the volatile water, and add 3 liters to the end of the medicine and mix well. (3) Dry at 65 °C. (4) Smashed through a 120 mesh sieve for storage at a young age. The active ingredient rhizome contains diosgenin-3-0- a _L-purine arabinose (1+4)-[α-L-呲-rhamnosyl (1+2)]-cold-D- ° {diosgenin-3-o-α-L-arabinofuranosyl(l->4)-[ a -L-rhamnopyranosyl(l —2)]}- β -D-glucopyranoside}, and various polymorphic elements, Glycosyl, sugar ring and other ingredients. Originally recorded pharmacological effects Calm nerves, dredge lymphoid organs and defense tissues, eliminate heterogeneity, and eliminate inflammation in organs, tissues, and liver. Pharmacological application, purpose to clear the lymphatic organs and defense tissue, and exclude heterogeneity. -46-

Claims (1)

12602261260226 拾、申請專利範圍 ι_一種治療淋巴結關係型癌症的中藥複方，係包含有黨參 (Codonopsis Pilosula)、黃芪（Astragalus membranaceus)、薏苡 仁（Coix Lacyma-Jobi)、山佩蘭（Eupatorium japonicum)、橘皮 (Citrus reticulata)、爵床(Rostellularia procumbens)、夏枯草 5 (Prunella Vulgaris)、涼粉草（Mesona chinensis)、振子（Gardenia jasminoides)、連赵（Forsythia suspensa)、赤芍（Paeonia Veitchii)、大黃（Rheum officinale)、番蟲（Eupolyphaga sinensis)、白花蛇舌草（Hedyotis diffusa)、杠板歸(Polygonum per foliatum)、山豆根（Sophora tonkinensis)、木槿皮（Hibiscus 10 syriacus)、天南星(Arisaema heterophyllum)、半邊蓮(Lobelia chinensis)、白蔹（Ampelopsis joponica)、漏蘆（Rhaponticum uniflorum)、石葦（Pyrrosia sheared)、乳香（Boswellig carterii)、沒藥（Commiphora Myrrha)、蚤休(Paris polyphylla)、 敗醬（Patrinia Villosa)、白 (Angelica dehurica)、射幹 15 (Belamcanda chinensis)、蒲公英（Taraxacum mongolicum)、螺 f 草（Lemmaph yllum microphyllum presl)、皂莢（Gledltsia sinensis)、獨活（Angelica biserrate)、麻黃（Ephedra SmlCa)、 升麻(Cimicifugafoetida)等藥物。 2.如申請專利範圍第1項所述之醫藥組成物，其配比如 20 下：黨參 1.94%-3.94%、黃芪 1·94%-3.94%、薏苡仁 1·94%-3·94%、山佩蘭 i·94%-3.94%、橘皮 i.94%-3.940/0、 爵床1·94%-3·94%、夏枯草丨·94%-3.94%、涼粉草 I 94%-3.94〇/。、樵子 i·94%-3·94%、連 ^ 1.94%-3.94% ^ Λ* 1.94〇/〇-3.94〇/〇 ^ f/, 1.94%-3.94% > 阴續額（申請專利範酿不雛鹏，請註記並使臓頁） -69- 1260226Pick-up, patent application range ι_ A Chinese herbal compound for the treatment of lymph node-associated cancer, including Codonopsis Pilosula, Astragalus membranaceus, Coix Lacyma-Jobi, Eupatorium japonicum, orange peel (Citrus reticulata), Rostellularia procumbens, Prunella Vulgaris, Mesona chinensis, Gardenia jasminoides, Forsythia suspensa, Paeonia Veitchii, Rhubarb Rheum officinale), Eupolyphaga sinensis, Hedyotis diffusa, Polygonum per foliatum, Sophora tonkinensis, Hibiscus 10 syriacus, Arisaema heterophyllum , Lobelia chinensis, Ampelopsis joponica, Rhaponticum uniflorum, Pyrrosia sheared, Boswellig carterii, Commiphora Myrrha, Paris polyphylla, defeat Sauce (Patrinia Villosa), White (Angelica dehurica), Shooting 15 (Belamcanda chinensi s), dandelion (Taraxacum mongolicum), snail f (Lemmaph yllum microphyllum presl), acacia (Gledltsia sinensis), an individual (Angelica biserrate), ephedra (Ephedra SmlCa), cohosh (Cimicifugafoetida) and other drugs. 2. For the pharmaceutical composition as described in item 1 of the patent application, the composition is as follows: 20: Codonopsis 1.94%-3.94%, Astragalus 1.94%-3.94%, Coix seed 1.94%-3.94%, Shan Peilan i·94%-3.94%, orange peel i.94%-3.940/0, Jue bed 1.94%-3·94%, Prunella vulgaris·94%-3.94%, jelly grass I 94%-3.94 〇/. , 樵子 i·94%-3·94%, even ^ 1.94%-3.94% ^ Λ* 1.94〇/〇-3.94〇/〇^ f/, 1.94%-3.94% > Yin renewal (patent application) Not brewing, please note and make the page) -69- 1260226 15 才 1 94%-3·940/〇、山立根 ι94%-3·94。/。、木槿皮 h9 〇 ρ ι94%-3·94%、漏盧 辜邊蓮—-鄉二二乳香…。/『—、沒 i.94%-3.94。/。、石韋 i·94 ° 敗醬 i.94%-3·%%、 藥194%_3.94%、蚤休1如/^_9194%_3 94%、蒲公英白芷 1·94%-3·94%、射 皂爷 1 94%-3.94%、總感蓋 1 94%-3·94%、皂爽 i.9470 19413.94%、螺 ^戈· 94%、升麻 194%_3.94%。 獨活2 _述之«組成物，其最佳配 3.如申二2 9:、黃笑”4%、薏炫仁2.94%、山佩蘭 比如下··黨參2·9 、心。/曹枯箪2 94%、凉粉草 2.94%、橘皮2._、爵床2·94%、夏枯草2二_、 2.94%、穩子 2.94%、輪 2.94%、赤 Ρ.94%、大《 2.94一/。 蜜蟲2.94%、白花蛇舌草2.94%、杠板歸2.94%、山且根 2.94%、木槿皮2.94%、天南星2.94%、半邊蓮2.94%、白 蔹2.94%、漏蘆2.94%、石葦2.94%、乳香2.94%、沒藥 2·94%、蚤休 2.94%、敗 f 2.94%、白 2.94%、射幹 2.94%、 蒲公英2.94%、螺礞草2.94%、皂莢2.94%、獨活2.94%、 麻黃2.94%、升麻2·94%。 4. 如申請專利範圍第2項所述之醫藥組成物，更包含有 获茶(Poria cocoa)，係為萃取賦形藥。 5. 如申請專利範圍第4項所述之醫藥組成物，該茯苓含 量為9.85%。 6. 如申請專利範圍第1項所述之醫藥組成物，其係形成 總重0.5gm之疑片。 白15 only 1 94%-3·940/〇, Shan Ligen ι94%-3·94. /. , wood suede h9 〇 ρ ι94%-3·94%, leaking Lu Bianbianlian--township two frankincense... / "-, no i.94%-3.94. /. , Shi Wei i·94 ° defeat sauce i.94%-3·%%, medicine 194%_3.94%, 蚤休1如/^_9194%_3 94%, dandelion white 芷1·94%-3·94% , saponin 1 94% -3.94%, total cover 1 94% -3.94%, soapy i.9470 19413.94%, snail ^ 94%, cumin 194% _3.94%. Living alone 2 _ described « composition, its best match 3. Such as Shen 2 2 9:, Huang Xiao" 4%, Yan Xuanren 2.94%, Shan Peilan such as the next · · Codonopsis 2 · 9 , heart. / Cao Withered 2 94%, jelly grass 2.94%, orange peel 2._, Jue bed 2.94%, Prunella vulgaris 2 2, 2.94%, stable 2.94%, round 2.94%, red Ρ.94%, large 2.94 a. 2. 2.94% of honeysuckle, 2.94% of Hedyotis diffusa, 2.94% of bark, 2.94% of mountain roots, 2.94% of hibiscus, 2.94% of Tiannanxing, 2.94% of lobelia, 2.94% of white peony, 2.94% of scorpion 2.94 %, sarcophagus 2.94%, frankincense 2.94%, myrrh 2.94%, sputum 2.94%, defeat f 2.94%, white 2.94%, shot dry 2.94%, dandelion 2.94%, snail grass 2.94%, acacia 2.94% 2.9% of live, 2.94% of ephedra and 2.94% of cohosh. 4. The pharmaceutical composition as described in item 2 of the patent application, including Poria cocoa, is an extracting drug. 5. The pharmaceutical composition according to item 4 of the patent application scope, the strontium content is 9.85%. 6. The pharmaceutical composition according to claim 1 of the patent application form a suspected piece having a total weight of 0.5 gm. . White 20 •70-20 •70-