1225461 A7 — —------B7_____ 五、發明說明（；） 【發明領域】 本發明大體上係有關撓性容器，而更特別地，係有關 大體積、立體撓性容器。 【發明背景】 用於液體（例如像治療液體或者使用在其它醫療應用 的'液體）之運輸、儲存和輸送的容器通常係由單一或者複 數聚合材料所製成。此材料典型地係成片體形式。此種材 料的兩個片體係置放成重疊的關係，並且該重疊的片體在 其周圍處聯繫在一起以界定一腔室或者袋囊以用來容納液 體。此種型式的袋子典型地係指平面撓性容器、平袋，或 者 ''枕袋〃。屬於Bacehowski以及其他人，並且一般歸屬 於本發明之受讓人 Baxter International Inc. (Bacehowski)的 美國專利案第4,968,624號揭露一種大體積、二維的撓性 容器。此種型式的袋子可以達到600公升大的容積。 雖然600公升對於撓性容器而言係足夠的，對於甚至 更大容積的撓性容器之需求已在增加中。此亦導致立體撓 性容器的發展，有時指稱爲〜立方袋體〃。 此種容積之立體袋容器的設計與使用遇到了某些問題 。藉由該容器所容納的大體積的液體施加液壓在該容器的 接縫上，其係在一種無支撐的狀態，可能足夠造成容器的 損壞。確實，這麼大的容器，當塡充了水或者其它的液體 時，可能超過3000磅重。與此種液體體積有關的力量可能 造成容器接縫毀壞或破裂，因此造成容器中的裂縫。藉由 3 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） (請先閱讀背面之注意事項再填寫本頁) · I I I----訂-- ---I I I I · 1225461 A7 _____B7_ __ 五、發明說明（>) 該容器所容納的液體不是普通的溶劑，而是一種無菌、特 製配方的溶劑。因此，甚至在任何接縫破裂中的非常小的 裂縫可能嚴重地危及容器中整個內容物的無菌性。並且， 容器接縫的損壞可能造成數百公升的液體逐漸地從容器流 失。替換流失的液體係非常昂貴的。並且也會遇到淸潔費 用的問題。 此種大體積、立體撓性容器並非傾向於自由的站立， 而是相反地，設計成藉由一剛性或者半剛性的支撐容器所 支撐，其一般係指稱一種箱櫃或者貯槽。該箱櫃可由多種 材料製成，一般爲不銹鋼。該不銹鋼材料通常對於要看到 盒體內部中係爲一種視覺阻礙。典型地，一操作者必須從 頂部往下看箱櫃內部。該箱櫃可能在一側壁上具有一存取 門以容許一操作者可看到該箱櫃的內部。然而，該門在尺 寸上係非常小並且無法提供位在該箱櫃之中的撓性容器的 完整的觀察。該側壁可能具有連續的小觀測孔以容許吾人 決定在容器之中液體的高度。然而，同樣地，此種小觀測 孔並未提供在箱櫃之中的容器的完整觀察。 根據所需，該箱櫃和撓性容器將具有某些相互作用。 對於被塡充的撓性容器而言較爲理想的是將負載以及相關 的力量從所容納的液體轉移到該箱櫃，因此最小的負載（ 較佳地爲零）係被該撓性容器材料所支承，特別係該容器 接縫。其亦較爲理想的是，該容器接縫係被完全地支撐以 防止該容器因爲、、塑性變形〃而損壞，其係關連至因爲少 量但是連續的張力造成的密封完整性之損失。 4 本纸張尺國國家標準（CNS)A4規格（210 X 297公--- (請先閱讀背面之注意事項再填寫本頁) 丨裝 ----訂---------線泰 1225461 A7 _________BL_ 五、發明說明（、） 因爲容器大小的關係，其可能非常困難正確地將該容 器對位在該箱櫃之中。而一開始正確地對位，該撓性容器 在容器塡充期間可能位移而變成錯位。如果錯位的話，該 容器可能會具有多餘的折線，當該袋子係被塡充時其不會 正確地展開。從錯位所造成的此種容器折線可能導致過度 的應力在容器接縫上導致容器毀壞。 舉例而言，當該容器係塡充有液體時，該容器膨脹並 且符合該環繞的箱櫃。理想地，該容器符合係盡可能的靠 近該箱櫃的內壁，雖然容器的打褶可能發生。在適當的時 間，該液體係從該容器排放出，其中該容器塌陷。如果該 容器係沒被支撐，其將會傾向於塌陷成水平摺痕。此摺痕 可困住在容器中的液體，因此無法讓容器完全地排放。在 某些例子中，一旦該容器被排放時，該容器已達成其目的 而隨後被丟棄。在其它的例子中，在較大的程序中的一部 分，該容器可能被再次塡充。在此種情況下，於再塡充程 序期間，該容器水平的摺痕可能限制所希望的重新組合。 此可導致不良的定位或者該容器有效容積的損失。其亦可 能導致該容器不足夠的支撐。因此，其亦理想的是垂直地 支撐該容器於該箱櫃內以有效地進行排放或者塡充程序。 當第二次塡充該容器時，垂直支撐容器於箱櫃內係特別地 重要。 美國專利案第5,988,422號係指一種用於生化配藥液 體產品的小袋。雖該小袋係爲一種立體容器’該容器在其 側面之間並不具有最理想的角度結構。此將會衝擊此種容 ! 5 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） (請先閱讀背面之注意事項再填寫本頁) 訂-------線·. 1225461 A7 ______B7 _________ 五、發明說明（\ ) 器如何被支撐在一箱櫃之中。因此，該容器之最理想的塡 充、排放，和再塡充係無法達成。 某些大體積撓性容器通常使用一剛性或者半剛性管， 使用於該容器的塡充或者排放時，其經常稱作一種''浸入 管〃。該浸入管係附接至該容器的頂部並且向下延伸至該 容器底部內表面。在排放期間，該浸入管支撐該容器頂部 板片的中央部分，而較像是一種架棚支柱。在此種結構中 ，在該容器排放期間，該浸入管產生垂直摺痕，並且亦容 許對於該容器再塡充使用。 然而，該浸入管具有數種缺點。第一，如果該容器接 地面積幾何形狀係遠比圓形複雜時，該浸入管無法定位該 容器的末端垂直表面。除此之外，當該容器係被排放時， 該容器的壁部朝著中心聚集而大體上產生壓縮負載於該浸 入管上。此壓縮力可能造成數種問題。在此種力量下該浸 入管其本身可能彎曲。該浸入管和該容器頂部之間的接縫 可能被危及。該浸入管的底部部分亦可能使得該容器底部 破裂。使用一浸入管結構亦增加了該容器系統的成本。除 此之外，浸入管隨著容器排氣時會讓空氣進入替代液體， 因此該容器材料不會塌陷。最後，該浸入管亦可能有另— 種讓污染物進入容器之內容物的潛在問題。因此，其仍需 要一種垂直支撐系統用於箱櫃內的容器，其滿足排放和再 塡充之所需而不具有額外複雜的浸入管和閥門。 此種大體積容器典型地亦配備有一個或更多個填口， 該埠口配備有用於存放容器內之液體的埠□封閉器。該容 6 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐) ^ ----— (請先閱讀背面之注意事項再填寫本頁} --------訂-------- 1225461 A7 __ B7 ~ -_ιιι·ι 丨 丨丨 _丨 一 五、發明說明（S ) (請先閱讀背面之注意事項再填寫本頁) 器可在底部板片中具有該埠口，其開放至該容器內。通常 ，該埠口封閉器包含一管，該管有一端連接至該埠口。因 爲該容器經常係使用在醫療和生化科技應用，該埠口封閉 器必須包含用於將該管的另一個自由端維持在不被污染的 機構。換句話說，該管的自由端必須配備有一無菌封閉器 ，其防止可能的污染物進入管和容器之中。然而，其亦需 要容許空氣進入容器之中，因爲其促進容器在操作及安裝 期間的操作性。 有兩種普通的方法用來提供一無菌的封閉器於該管的 自由端。第一，該管的自由端可被密封關閉。在此應用之 中，該管件必須從熱塑性材料選出，諸如PVC或者聚乙烯 ，其容許材料的密封。此材料可以被加熱密封，或者使用 其它密封能源加以密封，諸如射頻或者超音波。在製造程 序應用中使用砂管係爲理想的。舉例而言，一泵可連接至 該管件以用於長期間’因此該液體可從容器中抽取出。該 矽管亦具有抵抗高溫的能力，特別當該管的末端係使用定 位流方法（S.I.P)殺菌時。然而，一種問題存在於使用一 密封矽管之中，係爲當提供一無菌封閉時，其並不促進氣 體的自由通過。氣體轉換（排氣）對於促進容器在處理和 安裝期間的操作性係爲理想的。除此之外，對於存取一具 有密封管的容器，操作者必須使用一鋒利的工具，諸如小 刀、刀片或者其它裁切用具以開啓該管。此導入污染該管 的一個機會，並且亦引起傷及操作者的風險。 第二種用於提供一無菌封閉在該管的自由端之方法係 本紙張尺國國家標準（CNS)A4規格--- 1225461 A7 _________Β7 _ 五、發明說明（丄） 使用一成型元件，諸如一射出鑄造部件或者不銹鋼聯結器 。該管件係裝配至該部件或者聯結器，並且隨後該部件或 聯結器係覆蓋另一個匹配的射出鑄件或者聯結器。與密封 管方法相同，此種配接提供一無菌封閉，但是並不提供器 體轉換而不會損失無菌性者。除此之外，使用射出鑄件或 者不銹鋼聯結器係爲昂貴的。 本發明係提供解決此種和其它的問題者。 【發明槪要】 本發明係有關於容器，並且更特別地，係有關大體積 、立體撓性容器 根據本發明的第一個態樣，係提供一種容器，其具有 複數個板片結合在一起以形成一套筒。該等板片每一個皆 具有一末端邊緣其相互合作以界定一假想面於該套筒的其 中一端。該容器進一步具有一末端板片連接至該等板片於 該套筒的另一端。該末端板片具有至少一部分延伸超過於 該假想面上。根據本發明的另一個態樣，該板片形成一多 邊形套筒。該末端板片的該部分係從該套筒向外地延伸。 或者，該部分可朝向該套筒向內地延伸。 根據本發明進一步的態樣，係提供一種大體積撓性容 器能夠容納液體，將液體維持在無菌的狀況下。該容器具 有一第一板片、一第二板片、一第三板片，和一第四板片 ’其連接在一起以形成一大體上立方形的結構。該第一板 片具有一中央區段鄰近於一末端區段。該中央區段具有一 8 ________ 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐) " (請先閱讀背面之注意事項再填寫本頁) -----訂--------- 1225461 A7 ______________B7_______ 五、發明說明（、） 圖3 係本發明之另一種醫療液體容器之立體圖，其 係比顯示於圖1和圖2中之容器爲大，且顯示成垂直形態 圖4 係圖1之容器的側視圖； 圖5 係容器之板片的平面圖； 圖6 係容器之角撐板之平面圖； 圖7 係容器之端板之立體圖； 圖8 係本發明之容器之立體圖，其係成大體上折疊 的形態，一支撐盒係以虛線顯示； 圖9 係圖8之容器的立體圖，其係在一塡充程序期 間塡充有液體； 圖10 係與該容器一起使用的埠口封閉器的平面圖； 圖1 1 係圖1 0中的璋口封閉器之另一種結構的平 面圖； 圖1 2 係一璋口封閉器之立體圖，其係連接至一容 -πσ ， 圖1 3 係一容器之立體圖，其具有多個埠口，而以 一埠口封閉器連接至其中一個埠口，並且以另一種埠口封 閉器連接至另一個埠口。 【元件符號說明】 10 容器 1 2 第一板片 10 本紙張尺度國國家標準（CNS)A4 χ 297公釐) --- (請先閱讀背面之注意事項再填寫本頁) 『裝 Τ mmee ^^1 J t —ϋ i·— n 1_ n n fen I 言 1225461 A7 五、發明說明（1 ) 14 16 18 2 0 2 2 2 4 2 6 2 8 3〇 3 2 3 4 3 6 3 8 4 0 4 1 4 2 4 4 4 6 4 8 5 0 5 2 5 4 5 6 6〇 第二板片 第一側角板 第二側角板 第一角端板 第二角端板 中央區段 第一末端區段 第二末端區段 第一周圍邊緣 第二周圍邊緣 縱長部 漸縮部 末端邊緣 埠口 埠口 角中央區段 第一角末端區段 第二角末端區段 第一周圍邊緣 第二周圍邊緣 縱長部 漸縮部 點 側邊接縫 (請先閱讀背面之注意事項再填寫本頁) --------訂·-------- 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） 1225461 A7 ___ B7 五、發明說明（一） 6 2 端板接縫 6 3 末端邊緣 6 4 套筒 17 3 小孔 3 0 0 埠口封閉器 3 0 2 連通元件 3 0 4 堵塞元件 3 0 6 覆蓋元件 3 0 8 箍帶 3 0 9 收縮帶 3 1〇 第一元件 3 1 2 第二元件 3 14 第一末端 3 16 繩帶 3 18 第二末端 3 2 0 開□末端 3 2 2 囊袋 3 2 4 頂部邊緣 3 3 0 埠口 3 3 2 排氣封閉器 3 3 4 短矽管 3 3 6 排氣栓塞 3 3 8 閥門 A 角度 12 (請先閱讀背面之注意事項再填寫本頁) --------訂·--------· 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） 1225461 A7 -—--— _B7 五、發明說明（：、\ ) B 角度 F L 折疊線 G F 角折疊線 【詳細說明】 雖本發明係容許多種不同的實施例，其顯示於圖式中 且將在本文中詳說明者係本發明之較佳實施例，其應瞭解 的是所揭露者係爲本發明之原理的範例，而並非以所繪示 的實施例加以限制本發明寬廣的態樣。 請參照圖式，圖1顯示一個根據本發明所構建的容器 ’其大體上以元件符號1 〇所表示。該容器1 〇係爲立體 的容器而能夠容納大量的液體。顯示在圖1中的容器1 〇 容納了大約200公升的液體。然而，該容器1 0可以作成 不同的大小。舉例而言，圖2顯示一容器1 0限制尺寸成 容納大約500公升的液體，而圖3顯示一容器1 0限制尺 寸成容納大約1500公升的液體。該容器1 0具有獨特的結. 構，其減少藉由來自容納在該容器1 0中的液體所產生的 液壓對於該容器1 0所造成的接縫應力。 如顯示於圖1中，該容器1 0係爲立體的且大體上具有 一矩形的形狀其具有六面，或者有時指具有四面和兩端者。 該容器1 0大體上係從四個板片形成：一第一板片1 2 (或者是頂部板片1 2)，一第二板片1 4 (或者是底 部板片14)，一第一側角板16以及一第二側角板18 。這些牆板1 2至1 8形成該容器的四個板片，並且每個 13 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） (請先閱讀背面之注意事項再填寫本頁) _裝--------訂-------- 1225461 A7 _B7_______ 五、發明說明（V> ) 牆板的末端部相互結合以形成該立體容器1 0剩餘的兩個 板片，一第一角端板2 0和一第二角端板2 2。個別的牆 板將首先被說明，而之後將說明該牆板之間的連接關係以 顯示該容器10的結構。 圖5顯示該第一板片1 2 (或者是頂部板片12 )的 平面圖。其可以瞭解的是，該第二板片1 4 (或者是底部 板片1 4 )具有相似的結構，而將不會再單獨地說明之。 該頂部板片1 2大體上具有一中央區段2 4、一第一末端 區段2 6以及一第二末端區段2 8。一折疊線F L代表該 中央區段2 4和末端區段2 6、2 8之間的接合部。該末 端區段2 6、2 8係被折疊且與其它板片的末端區段相互 合作而相配合地形成該端板2 0、2 2，如將在下文中更 詳細之說明者。 如進一步地顯示於圖5中，該頂部板片1 2具有一第 一周圍邊緣3 0以及一第二周圍邊緣3 2。每一個周圍邊 緣3 0、3 2在中央區段2 4處皆具有一縱長部3 4，並 且在第一末端區段2 6和第二末端區段2 8處具有一漸縮 部3 6。在每一個末端區段2 6、2 8處，該漸縮部3 6 朝著彼此聚集，但並沒有接合。更確切地說，該漸縮部3 6交會一末端邊緣3 8。如將在下文作更詳細的說明，該 周圍邊緣3 0、3 2的縱長部3 4與該漸縮部3 6交會成 一角度A。同樣地，一角度B存在於該漸縮部3 6以及該 折疊線F L之間。該角度A和角度B較佳的度量將會在下 文中作更詳細的說明，其將該容器1 〇的接縫強度完美化 14 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） (請先閱讀背面之注意事項再填寫本頁) I » ϋ n I n ϋ n ϋ 一一口*, a I I n n n n n I · 1225461 A7 _ - - _ B7___ 五、發明說明（） 。如果需要的話，該頂部板片1 2可以包含一埠口 4 0。 該底部板片1 4亦可以具有一埠口 4 0。一額外的部口 4 1亦可被提供（圖1)。其係可瞭解的是，埠口可定位在 該容器1 0的任一個板片中。 圖6揭露該第一側角板16的平面圖。其係可瞭解的 是，該第二側角板1 8具有相似的結構，而將不會再分別 地說明之。該第一側角板1 6亦具有一角中央區段4 2、 一第一角末端區段4 4和一第二角末端區段4 6。一折疊 線F L代表該角中央區段4 2和角末端區段4 4、4 6之 間的接合部。該角末端區段4 4、4 6係被折疊並且與頂 部板片1 2和底部板片1 4的末端區段2 6、2 8相互合 作而相配合地形成該端板2 0、2 2，如將在下文中更詳 細之說明者。 如進一步地顯不於圖6中，該角板1 6具有一第一周 圍邊緣4 8以及一第二周圍邊緣5 0。每一個周圍邊緣4 8、5 0在該中央區段4 2處皆具有一縱長部5 2，並且 在該第一角末端區段4 4和第二角末端區段4 6處具有一 漸縮部5 4。在每一個角末端區段4 4、4 6處，該漸縮 部5 4朝著彼此聚集，並且交會於一點5 6處。如將被揭 露者，該角板1 6、1 8大體上在該板片中心線處具有一 角折疊線G F。該板片1 6、1 8於該角折疊線G F處向 內地折疊。 將該容器1 0建構成立體的形式中，該板片1 2至1 8的周圍邊緣大體上係藉由此技藝中習知合適的方法接合 15 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） (請先閱讀背面之注意事項再填寫本頁) _裝--------訂---------^^1 1225461 A7 ____ —_B7_ 五、發明說明（θ) ’諸如熱能、RF能、音波或者其它的密封能量。該第一和 第二側角板係被定位成隔開該頂部板片12和底部板片1 4 °該頂部板片1 2之周圍邊緣係密封至該側角板1 6、 1 8各別的周圍邊緣以形成接縫。同樣地，該底部板片1 4 的周圍邊緣係密封至該側角板1 6、1 8相對的周圍邊緣 。特別地，舉例而言，該頂部板片1 2的周圍邊緣3〇係 被密封至該第一側角板1 6的周圍邊緣4 8，其中各別的 縱長部3 4、5 2係密封在一起以形成一側邊接縫6 0 ( 圖1)，並且各別的漸縮部36、54係密封在一起以形 成端板接縫6 2。以此種方式，且如同顯示在圖1之中， 該撓性容器1 0係被形成大體上具有立體矩形形狀。該板 片1 2至1 8的中央區段2 4、4 2形成該容器1 〇的側 面。該第一板片1 2和第二板片1 4的末端區段2 6、2 8以及該側角板1 6、1 8的末端區段4 4、4 6合作形 成該角端板2 0、2 2。以此種結構，該末端區段2 6、 2 8、4 4、4 6作爲連接元件以形成該端板2 0、2 2 。該末端區段朝著彼此聚集且可被安裝成接合於一點、一 線或者一多邊形處。在一較佳實施例中，該末端區段聚集 至一線段。其係可進一步瞭解的是，該容器1 0可被建構 成任何Ν數面的多邊形形狀。其係可進一步瞭解的是，該 各別的板片可包含複數個分離的板片連接在一起以形成該 容器1 0的板片。此可以形成，舉例而言，將該容器1 0 作成甚至比顯示於圖3中之1500公升的容器還大。 在一典型的立體容器的建構中，角Β將會是45度，而 16 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） (請先閱讀背面之注意事項再填寫本頁) i —ϊ I H 一 δ、a n m 1 = ϋ n >11 t · 1225461 A7 五、發明說明（Λ ) ^周圍雜3 Q、3 2的縱長部3 4麵縮部3 6之間 白(圖5 )作成135度。此將會提供—種結構例如像 疋该_板2 0、2 2將會大體上垂直於該板片1 2至1 8 的2央區段2 4、4 2。在本發明的容器1 〇中，該角A 係從135 f增加至大約從135·01度至138度的範圍之中。 在最佺貫施例中，該角a係大約爲Β6度。藉由增加此 ，度’更多的材料係被提供在該角端板2 0、2 2中。如 顯不於圖4之中，此額外的材料容許該端板2 0、2 2從 中央區段2 4、4 2向外地延伸而提供一種「單斜屋頂」 (曰靑参照圖2、圖4和圖7 )。如進一步顯示在圖4中， 該板片1 2至1 8，當連接在一起時係形成一套筒6 4。 該套筒6 4係形成矩形平行管形狀之型式。該板片每一個 皆具有一末端邊緣6 3，其在折疊線F L處係相對應於該 中央區段之末端。該末端邊緣6 3於該套筒6 4末端處界 定了一個假想面P。該端板2 〇、2 2具有至少一個延伸 越過該假想面P的部分。在一最佳實施例中，該端板係與 該套筒成連續狀，並且該整個端板2 0、2 2延伸越過該 假想面P。在此種結構中，該套筒6 4的末端邊緣係藉由 g亥折疊線F L所代表。使用此種延伸的結構，當該容器1 0係塡充液體時，在端板接縫6 2上的應力係減少。此亦 防止額外的應力被轉換至該容器1〇其它的部位。 圖8和圖9揭露一種用於諸如顯示在圖1和圖2中的 容器1 0 (例如，呈水平狀態的容器1 0 )的塡充程序。 一開始爲了淸楚起見，該容器1 0係顯示成脫離該支撐箱 17 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） (請先閱讀背面之注意事項再填寫本頁)1225461 A7 — — ------ B7_____ V. Description of the Invention (;) [Field of the Invention] The present invention relates generally to flexible containers, and more particularly, to large-volume, three-dimensional flexible containers. BACKGROUND OF THE INVENTION Containers for the transportation, storage, and delivery of liquids, such as therapeutic liquids or 'liquids' used in other medical applications, are generally made of a single or multiple polymeric materials. This material is typically in the form of a sheet. The two sheet systems of such a material are placed in an overlapping relationship, and the overlapping sheet bodies are connected at their surroundings to define a cavity or pouch for containing a liquid. This type of bag is typically a flat flexible container, a flat bag, or a '' pillow bag ''. U.S. Patent No. 4,968,624 to Bacehowski and others, and generally to the assignee of the present invention, Baxter International Inc. (Bacehowski), discloses a large, two-dimensional, flexible container. This type of bag can reach a large volume of 600 liters. Although 600 liters is sufficient for flexible containers, the demand for even larger volumes of flexible containers has been increasing. This has also led to the development of three-dimensional flexible containers, sometimes referred to as ~ cubic pouches. Some problems have been encountered in the design and use of such a three-dimensional bag container. Hydraulic pressure is applied to the seams of the container by the large volume of liquid contained in the container, which is in an unsupported state, which may be sufficient to cause damage to the container. Indeed, such a large container, when filled with water or other liquids, can weigh more than 3,000 pounds. The forces associated with this volume of liquid can cause the joints of the container to break or break, thus causing cracks in the container. With 3 paper sizes, the Chinese National Standard (CNS) A4 specification (210 X 297 mm) is applied (please read the precautions on the back before filling this page) · II I ---- Order---- IIII · 1225461 A7 _____B7_ __ 5. Description of the invention (>) The liquid contained in the container is not a common solvent, but a sterile, specially formulated solvent. Therefore, even very small cracks in any seam rupture can seriously endanger the sterility of the entire contents of the container. Also, damage to the seams of the container may cause hundreds of liters of liquid to gradually drain from the container. Replacing a lost fluid system is very expensive. You will also encounter problems with cleaning costs. Such large-volume, three-dimensional flexible containers do not tend to stand freely, but instead are designed to be supported by a rigid or semi-rigid support container, which is generally referred to as a cabinet or storage tank. The cabinet can be made from a variety of materials, typically stainless steel. This stainless steel material is often a visual barrier to seeing inside the box. Typically, an operator must look inside the cabinet from the top. The cabinet may have an access door on a side wall to allow an operator to see the interior of the cabinet. However, the door is very small in size and cannot provide a complete view of the flexible container in the cabinet. The side wall may have small continuous viewing holes to allow us to determine the height of the liquid in the container. However, again, such small sight holes do not provide a complete view of the container in the cabinet. The cabinet and flexible container will have some interaction, as needed. For a filled flexible container, it is ideal to transfer the load and related forces from the contained liquid to the cabinet, so the smallest load (preferably zero) is covered by the flexible container material. The support is particularly tied to the seam of the container. It is also desirable that the container seam is fully supported to prevent the container from being damaged by plastic deformation, which is related to the loss of seal integrity due to a small but continuous tension. 4 National paper size (CNS) A4 specifications of this paper rule (210 X 297 male --- (Please read the precautions on the back before filling this page) Line Thai 1225461 A7 _________BL_ V. Description of the Invention (,) Because of the size of the container, it may be very difficult to correctly position the container in the cabinet. At the beginning, the flexible container is in the container. It may be displaced during filling and become misplaced. If misplaced, the container may have extra fold lines, which will not unfold properly when the bag is filled. Such container fold lines caused by misalignment may cause excessive Stress causes container damage on the seams of the container. For example, when the container is filled with liquid, the container swells and conforms to the surrounding cabinet. Ideally, the container conforms to the container as close as possible to the cabinet. The inner wall, although pleating of the container may occur. At the appropriate time, the liquid system is discharged from the container, where the container collapses. If the container system is not supported, it will tend to collapse into horizontal creases. This Creases can be sleepy The liquid in the container does not allow the container to be completely discharged. In some cases, once the container has been discharged, the container has achieved its purpose and is subsequently discarded. In other examples, in larger procedures The container may be refilled in part. In this case, during the refilling procedure, horizontal creases in the container may limit the desired recombination. This may result in poor positioning or the effective volume of the container Loss. It may also lead to insufficient support of the container. Therefore, it is also desirable to support the container vertically in the cabinet to effectively perform the discharge or refilling procedure. When refilling the container for the second time, The vertical support container is particularly important inside the cabinet. US Patent No. 5,988,422 refers to a pouch for biochemical pharmaceutical liquid products. Although the pouch is a three-dimensional container, the container does not have the most space between its sides. Ideal angle structure. This will impact this kind of content! 5 This paper size applies to China National Standard (CNS) A4 (210 X 297 mm) (Please read the back first Please pay attention to this page before filling in this page) Order ------- line ·. 1225461 A7 ______B7 _________ V. Description of the Invention (\) How the device is supported in a box. Therefore, the container is the most ideal. Filling, discharging, and refilling cannot be achieved. Some large-volume flexible containers usually use a rigid or semi-rigid tube. When used for filling or discharging the container, it is often referred to as a `` immersion tube ''. The immersion tube is attached to the top of the container and extends down to the inner surface of the bottom of the container. During the discharge, the immersion tube supports the central portion of the top plate of the container, more like a shed pillar. Here In this structure, during the discharge of the container, the immersion tube creates a vertical crease and also allows refilling the container. However, this immersion tube has several disadvantages. First, if the container's ground area geometry is much more complex than a circle, the immersion tube cannot locate the vertical surface of the end of the container. In addition, when the container is discharged, the wall portion of the container gathers toward the center to generate a compressive load on the immersion tube. This compressive force can cause several problems. The immersion tube itself may bend under this force. The joint between the immersion tube and the top of the container may be compromised. The bottom portion of the immersion tube may also rupture the bottom of the container. The use of an immersion tube structure also increases the cost of the container system. In addition, the immersion tube allows air to enter the replacement liquid as the container is vented, so the container material does not collapse. Finally, the immersion tube may also have another potential problem with allowing contaminants to enter the contents of the container. Therefore, there is still a need for a vertical support system for containers in a cabinet, which meets the needs of drainage and recharging without having additional complicated immersion pipes and valves. Such large-volume containers are also typically equipped with one or more filler ports, which are equipped with a port sealer for storing liquids in the container. The paper size of this paper applies to Chinese National Standard (CNS) A4 specification (210 X 297 mm) ^ ----— (Please read the precautions on the back before filling this page} -------- Order -------- 1225461 A7 __ B7 ~ -_ιιι · ι 丨 丨 丨 _ 丨 One, five, invention description (S) (Please read the precautions on the back before filling this page) The device can be in the bottom plate With the port, it opens into the container. Usually, the port closer includes a tube with one end connected to the port. Because the container is often used in medical and biochemical applications, the port is closed The device must include a mechanism for maintaining the other free end of the tube uncontaminated. In other words, the free end of the tube must be equipped with a sterile closure that prevents possible contamination from entering the tube and container. However, it also needs to allow air to enter the container because it promotes the operability of the container during handling and installation. There are two common methods for providing a sterile closure to the free end of the tube. First, the The free end of the tube can be hermetically closed. In this application, The fitting must be selected from a thermoplastic material, such as PVC or polyethylene, which allows the material to be sealed. This material can be heat sealed or sealed with other sealing energy sources, such as radio frequency or ultrasound. The use of sand tubing in manufacturing process applications is Ideal. For example, a pump can be connected to the tube for a long period of time 'so the liquid can be extracted from the container. The silicon tube also has the ability to withstand high temperatures, especially when the end of the tube uses a locating flow Method (SIP) sterilization. However, a problem exists in the use of a sealed silicon tube, which does not promote the free passage of gas when a sterile seal is provided. Gas switching (exhaust) is useful for promoting container processing And the operability during installation is ideal. In addition, for accessing a container with a sealed tube, the operator must use a sharp tool, such as a knife, blade or other cutting tool, to open the tube. This An opportunity to introduce contamination of the tube and also pose a risk of injury to the operator. The second is to provide a sterile seal in The method of the free end of the pipe is the national standard (CNS) A4 of this paper rule --- 1225461 A7 _________ Β7 _ V. Description of the invention (丄) Use a molding element, such as an injection-molded part or a stainless steel coupling. Assembled to the component or coupling, and then the component or coupling is covered with another matching injection casting or coupling. As with the sealed tube method, this fitting provides a sterile closure, but does not provide body conversion but Those who do not lose sterility. In addition, the use of injection castings or stainless steel couplings is expensive. The present invention provides those who solve this and other problems. [Inventive Summary] The present invention relates to containers, and More particularly, it relates to a large-volume, three-dimensional flexible container. According to a first aspect of the present invention, a container is provided having a plurality of plates bonded together to form a sleeve. The plates each have an end edge that cooperates to define an imaginary face at one end of the sleeve. The container further has an end plate connected to the plates at the other end of the sleeve. The end plate has at least a portion extending beyond the imaginary plane. According to another aspect of the invention, the plate is formed into a polygonal sleeve. The portion of the end plate extends outwardly from the sleeve. Alternatively, the portion may extend inwardly toward the sleeve. According to a further aspect of the present invention, there is provided a large-volume flexible container capable of containing a liquid and maintaining the liquid under a sterile condition. The container has a first plate, a second plate, a third plate, and a fourth plate 'which are connected together to form a substantially cubic structure. The first plate has a central section adjacent to an end section. The central section has an 8 ________ This paper size is applicable to China National Standard (CNS) A4 (210 X 297 mm) " (Please read the precautions on the back before filling this page) ----- Order-- ------- 1225461 A7 ______________B7_______ V. Description of the Invention (,) Figure 3 is a perspective view of another medical liquid container of the present invention, which is larger than the container shown in Figures 1 and 2, and is displayed as Fig. 4 is a side view of the container of Fig. 1; Fig. 5 is a plan view of a plate of the container; Fig. 6 is a plan view of a gusset plate of the container; Fig. 7 is a perspective view of an end plate of the container; A perspective view of the container, which is generally folded, a support box is shown in dotted lines; Figure 9 is a perspective view of the container of Figure 8, which is filled with liquid during a filling process; Figure 10 is with the container A plan view of a port sealer used together; Figure 11 is a plan view of another structure of the porthole sealer in Figure 10; Figure 1 2 is a perspective view of a porthole sealer, which is connected to a container -πσ Figure 1 3 is a perspective view of a container, which has A port of entry, and is connected to a port to which a port is closed port opening, and is connected to another port of entry port to another port is closed. [Description of component symbols] 10 Containers 1 2 First plate 10 National paper standard (CNS) A4 x 297 mm of paper size) --- (Please read the precautions on the back before filling this page) 『装 Τ mmee ^ ^ 1 J t —ϋ i · — n 1_ nn fen I 1221222541 A7 V. Description of the invention (1) 14 16 18 2 0 2 2 2 2 2 2 2 2 3 2 3 4 3 6 3 8 4 0 4 1 4 2 4 4 4 6 4 8 5 0 5 2 5 4 5 6 6〇 Second plate first side corner plate second side corner plate first corner end plate second corner end plate central section first end zone Segment second end section first peripheral edge second peripheral edge lengthwise tapered end edge edge port opening corner central section first corner end section second corner end section first peripheral edge second peripheral edge longitudinal Long side tapered point side seam (Please read the precautions on the back before filling this page) -------- Order · -------- This paper size applies to Chinese National Standard (CNS ) A4 size (210 X 297 mm) 1225461 A7 ___ B7 V. Description of the invention (1) 6 2 End plate seam 6 3 End edge 6 4 Sleeve 17 3 Small hole 3 0 0 Port seal 3 0 2 Connect Element 3 0 4 blocking element 3 0 6 covering element 3 0 8 band 3 0 9 shrink band 3 1 0 first element 3 1 2 second element 3 14 first end 3 16 cord 3 18 second end 3 2 0 open □ End 3 2 2 Pouch 3 2 4 Top edge 3 3 0 Port 3 3 2 Exhaust sealer 3 3 4 Short silicon tube 3 3 6 Exhaust plug 3 3 8 Valve A angle 12 (Please read the precautions on the back first (Fill in this page again) -------- Order · -------- · This paper size applies to China National Standard (CNS) A4 (210 X 297 mm) 1225461 A7 --------- _B7 V. Description of the Invention (:, \) B Angle FL Folding Line GF Angle Folding Line [Detailed Description] Although the present invention allows a variety of different embodiments, which are shown in the drawings and will be explained in detail herein For the preferred embodiment of the present invention, it should be understood that the disclosed is an example of the principle of the present invention, and not to limit the broad aspect of the present invention with the illustrated embodiment. Referring to the drawings, FIG. 1 shows a container ′ constructed according to the present invention, which is generally indicated by the element symbol 10. The container 10 is a three-dimensional container and can hold a large amount of liquid. The container 10 shown in Fig. 1 holds approximately 200 liters of liquid. However, the container 10 can be made in different sizes. For example, FIG. 2 shows a container 10 limited in size to hold approximately 500 liters of liquid, and FIG. 3 shows a container 10 limited in size to hold approximately 1500 liters of liquid. The container 10 has a unique structure, which reduces the seam stress on the container 10 caused by the hydraulic pressure generated by the liquid contained in the container 10. As shown in Figure 1, the container 10 is three-dimensional and generally has a rectangular shape with six sides, or sometimes referred to as having four sides and two ends. The container 10 is generally formed from four plates: a first plate 12 (or a top plate 12), a second plate 1 4 (or a bottom plate 14), and a first plate. The side corner plate 16 and a second side corner plate 18. These wall panels 12 to 18 form the four panels of the container, and each of the 13 paper sizes applies to the Chinese National Standard (CNS) A4 (210 X 297 mm) (please read the precautions on the back before filling (This page) _Installation -------- Order -------- 1225461 A7 _B7_______ V. Description of the invention (V >) The ends of the wall panels are combined with each other to form the remaining two of the three-dimensional container 10. Plate, a first corner end plate 20 and a second corner end plate 22. The individual wall panels will be explained first, and the connection relationship between the wall panels will be explained later to show the structure of the container 10. Fig. 5 shows a plan view of the first plate 12 (or the top plate 12). It can be understood that the second plate 1 4 (or the bottom plate 1 4) has a similar structure and will not be described separately. The top plate 12 generally has a central section 24, a first end section 26, and a second end section 28. A folding line FL represents a joint between the central section 24 and the end sections 26, 28. The end sections 26, 28 are folded and cooperate with the end sections of other plates to form the end plates 20, 22, as will be described in more detail below. As further shown in Fig. 5, the top plate 12 has a first peripheral edge 30 and a second peripheral edge 32. Each peripheral edge 3 0, 3 2 has a longitudinal portion 3 4 at the central section 24, and a tapered portion 3 6 at the first end section 26 and the second end section 28. . At each of the end sections 26, 28, the tapered sections 36 gather towards each other, but are not joined. More precisely, the tapered portion 36 meets an end edge 38. As will be described in more detail below, the longitudinal portions 34 of the peripheral edges 30, 32 and the tapered portions 36 intersect at an angle A. Similarly, an angle B exists between the tapered portion 36 and the folding line FL. The better measurement of the angle A and the angle B will be described in more detail below, which perfects the joint strength of the container 10. This paper size is applicable to the Chinese National Standard (CNS) A4 (210 X 297 mm) ）) (Please read the notes on the back before filling out this page) I »ϋ n I n ϋ n ϋ sip **, a II nnnnn I · 1225461 A7 _--_ B7___ 5. Description of the invention (). If necessary, the top plate 12 may include a port 40. The bottom plate 14 may also have a port 40. An additional port 41 can also be provided (Figure 1). It is understood that the port can be positioned in any plate of the container 10. FIG. 6 discloses a plan view of the first side corner plate 16. It is understood that the second side corner plate 18 has a similar structure, and will not be described separately. The first side corner plate 16 also has a corner central section 4 2, a first corner end section 44 and a second corner end section 46. A fold line F L represents the joint between the corner center section 42 and the corner end sections 44 and 46. The corner end sections 4 4 and 4 6 are folded and cooperate with the end sections 2 6 and 2 8 of the top plate 12 and the bottom plate 14 to form the end plates 2 0 and 2 2 in cooperation with each other. , As will be explained in more detail below. As further shown in Fig. 6, the corner plate 16 has a first peripheral edge 48 and a second peripheral edge 50. Each of the peripheral edges 48, 50 has a longitudinal portion 52 at the central section 42, and has a gradual change at the first corner end section 44 and the second corner end section 46. Shrink 5-4. At each of the corner end sections 4 4 and 4 6, the tapered portions 54 are gathered toward each other and meet at a point 56. As will be disclosed, the corner plates 16 and 18 generally have a corner fold line G F at the center line of the plate. The plates 16 and 18 are folded inward at the corner folding line G F. The container 10 is constructed in a three-dimensional form, and the peripheral edges of the plates 12 to 18 are generally joined by a suitable method known in the art. The paper size is in accordance with Chinese National Standard (CNS) A4. (210 X 297 mm) (Please read the precautions on the back before filling this page) _install -------- order --------- ^^ 1 1225461 A7 ____ —_B7_ V. DESCRIPTION OF THE INVENTION (θ) 'such as thermal energy, RF energy, sound waves, or other sealing energy. The first and second side corner plates are positioned to separate the top plate 12 and the bottom plate 1 4 °. The peripheral edges of the top plate 12 are sealed to the side corner plates 16 and 18 respectively. Around the edges to form seams. Similarly, the peripheral edges of the bottom plate 1 4 are sealed to the opposite peripheral edges of the side corner plates 16 and 18. In particular, for example, the peripheral edge 30 of the top plate 12 is sealed to the peripheral edge 48 of the first side corner plate 16, wherein the respective longitudinal portions 3 4 and 5 2 are sealed. Together to form a side seam 60 (Figure 1), and the respective tapered portions 36, 54 are sealed together to form an end plate seam 62. In this manner, and as shown in FIG. 1, the flexible container 10 is formed to have a substantially three-dimensional rectangular shape. The central sections 24, 42 of the plates 12 to 18 form the sides of the container 10. The end sections 2 6 and 2 8 of the first and second plates 12 and 14 and the end sections 4 4 and 4 6 of the side corner plates 16 and 18 cooperate to form the corner end plate 20. ,twenty two. With this structure, the end sections 26, 28, 4 4, 4 6 serve as connecting elements to form the end plates 20, 2 2. The end sections gather towards each other and can be mounted to join at a point, a line, or a polygon. In a preferred embodiment, the end segments are clustered into a line segment. It can be further understood that the container 10 can be constructed into a polygonal shape with any N-number plane. It is further understood that the respective plates may include a plurality of separate plates connected together to form the container 10. This can be formed, for example, by making the container 10 even larger than the 1500 liter container shown in FIG. 3. In the construction of a typical three-dimensional container, the angle B will be 45 degrees, and 16 paper sizes are applicable to China National Standard (CNS) A4 (210 X 297 mm) (Please read the precautions on the back before filling out this Page) i —ϊ IH-δ, anm 1 = ϋ n > 11 t · 1225461 A7 V. Description of the invention (Λ) ^ Peripheral miscellaneous 3 Q, 3 2 longitudinal portion 3 4 face reduction 3 3 white (Figure 5) 135 degrees. This will provide a structure such as, for example, the plate 2 0, 2 2 will be substantially perpendicular to the 2 central sections 2 4, 4 2 of the plate 12 to 18. In the container 10 of the present invention, the angle A is increased from 135 f to a range of approximately from 135.01 to 138 degrees. In the most consistent embodiment, the angle a is approximately B6 degrees. By increasing this, more materials are provided in the corner end plates 20, 22. As shown in Figure 4, this additional material allows the end plates 20, 22 to extend outward from the central sections 24, 4 2 to provide a "single pitched roof" (refer to Figure 2 and Figure 2). 4 and Figure 7). As further shown in Fig. 4, the plates 12 to 18 form a sleeve 64 when connected together. The sleeve 64 is formed in the shape of a rectangular parallel pipe. The plates each have an end edge 63, which corresponds to the end of the central section at the folding line FL. The end edge 63 defines an imaginary plane P at the end of the sleeve 64. The end plates 20, 22 have at least one portion extending beyond the imaginary plane P. In a preferred embodiment, the end plate is continuous with the sleeve, and the entire end plate 20, 22 extends beyond the imaginary plane P. In this structure, the end edge of the sleeve 64 is represented by the g-h fold line FL. With this extended structure, when the container 10 is filled with liquid, the stress on the end plate joint 62 is reduced. This also prevents additional stresses from being transferred to other parts of the container 10. 8 and 9 disclose a charging procedure for a container 10 (e.g., a container 10 in a horizontal state) such as that shown in FIGS. 1 and 2. At the beginning, for the sake of clarity, the container 10 was shown as being separated from the support box. The paper size is applicable to the Chinese National Standard (CNS) A4 (210 X 297 mm). (Please read the precautions on the back before filling in this. page)
* n n n n 1_ n 一δ,ν β ϋ ϋ ϋ n I I n I 1225461 A7 __B7 __ 五、發明說明（） 櫃（將被說明），雖然其係可瞭解的是，該容器10係被 置放於該箱櫃中後才塡充液體。該容器1 0係以該底部板 片1 4靠在該箱櫃的基部而被水平地置放。該容器1 0係 被壓平，其中該第一側角板1 6和第二側角板1 8可朝容 器1 0向內折疊，雖然它們在圖8中係顯示成延展開。當 該容器係在一支撐箱櫃之中時，該角端板2 0、2 2係被 折疊於該頂部板片1 2的頂部上方。在此種結構中，該容 器係容易地塡充。如顯示在圖9中，當該容器1 0係被塡 充時，該側角板1 6、1 8係被展開。如果該板片1 6、 1 8抵靠著該箱櫃懸掛，其防止該容器1 〇完全地膨脹開 ，其在該容器10的塡充和運輸其間可將過度的應力定位 在容器接縫上。圖9顯示該容器1 0部分地塡充。 圖2揭露另一種容器1〇其係被設計成容納大約500 ' 公升。圖3揭露一種甚至更大的容器1 〇，其設計成容納 大約1500公升。在顯示於圖3中之容器1 〇的尺寸，其有 時係需要構建該容器使得該角端板2 0、2 2係爲在該容 器1 0的頂部和底部。此種結構的容器可具有15呎的高度 。此給予該容器1 〇 —較小的接地面積，其係較爲理想的 因此其可承放在一標準的集裝架上。一垂直的接地面積亦 減少了藉由容器所佔用的地面空間，其在儲存大量的容器 上係很重要的。該容器1 〇具有大體上矩形的接地面積， 其提供了比具有同樣的高度而大體上爲圓柱形的容器較大 的整體容積。其係可瞭解的是，在具有垂直的結構的容器 1 0 (圖3 )中，該端板2 〇、2 2的其中一個可代表爲 18 ί紙張尺度適用中國國家彳?^ (CNS)A4規格(210 X 297公f ) ~ -~ (請先閱讀背面之注意事項再填寫本頁) I ----I------------' 1225461 A7 B7 五、發明說明（A) 底部板片，諸如顯示在圖3中的端板2 0 ° 圖1 0至圖1 3揭露一種根據本發明的場口封閉器3 〇0，其設計成提供一種用於該容器1 0之堤口 4 〇的關 閉。該ί阜口封閉器3 0 0同時提供一種無囷的和氣體可滲 透的防護體。該埠口封閉器3 0 0大體上包含一連通元件 3 0 2、一堵塞元件3 04、一覆蓋兀件3 0 6和一箍帶 3 0 8。該連通元件3 0 2典型地係呈一軟管的型式。該 軟管3 0 2典型地係從一彈性材料製成’諸如矽。該軟管 的尺寸可根據特殊的應用而改變。在一較佳實施例之中， 係使用3/4吋的軟管。該軟管3 0 2具有一第一末端和一 第二末端，並且該軟管的長度係藉由所欲的應用而決定之 。該堵塞元件3 0 4典型地係爲一栓塞3 0 4的型式。該 栓塞3 0 4典型地係爲圓柱狀並且係從透氣但具有排水性 的材料選出，使得其係容許諸如空氣的氣體通過，但是防 止液體從栓塞3 0 4流出。在一較佳的實施例中，該栓塞 3〇4係從一透氣彈性材料諸如聚乙稀所製成。聚四氟乙 烯材料亦可使用。其它的材料亦有可能，旦在加工後具有 排水性的材料也可以使用。該材料的毛細孔大小係限定尺 寸成使得其可以提供一種氣體可滲透性、無菌的防護體。 在一最佳的實施例中，該栓塞係可商業購得的一種p〇rex® 排水材料。該栓塞·3 0 4大體上係約爲！吋長，且具有一 直徑限定尺寸成使得當其係被***於該軟管3 〇 2的一末 端時，其將形成一種干涉配合。如進一步的顯示在圖工〇 (請先閱讀背面之注意事項再填寫本頁) ________^_________. ··* nnnn 1_ n a δ, ν β ϋ ϋ ϋ n II n I 1225461 A7 __B7 __ 5. Description of the invention () Cabinet (to be explained), although it is understandable that the container 10 is placed in the Fill the cabinet with liquid. The container 10 is placed horizontally with the bottom plate 14 against the base of the cabinet. The container 10 is flattened, wherein the first side corner plate 16 and the second side corner plate 18 can be folded inwardly toward the container 10, although they are shown in FIG. 8 as being unfolded in an extended manner. When the container is housed in a supporting box, the corner end plates 20 and 22 are folded over the top of the top plate 12. In this structure, the container is easily refilled. As shown in Fig. 9, when the container 10 series is filled, the side corner plates 16 and 18 series are unfolded. If the plates 16 and 18 hang against the cabinet, it prevents the container 10 from expanding completely, which can place excessive stress on the container seams during filling and transportation of the container 10 . Figure 9 shows the container 10 partially filled. Figure 2 discloses another container 10, which is designed to hold approximately 500 'liters. Figure 3 discloses an even larger container 10 designed to hold approximately 1500 liters. At the size of the container 10 shown in Fig. 3, it is sometimes necessary to construct the container such that the corner end plates 20, 22 are at the top and bottom of the container 10. Containers of this structure can have a height of 15 feet. This gives the container a small ground area, which is ideal, so it can be placed on a standard container rack. A vertical ground area also reduces the floor space occupied by the container, which is important when storing a large number of containers. The container 10 has a substantially rectangular ground area, which provides a larger overall volume than a container having a substantially cylindrical shape having the same height. It can be understood that, in the container 10 (FIG. 3) having a vertical structure, one of the end plates 20 and 22 can be represented as 18 ί paper size applicable to the Chinese national standard (CNS) A4 Specifications (210 X 297 male f) ~-~ (Please read the precautions on the back before filling this page) I ---- I ------------ '1225461 A7 B7 V. Description of the invention (A) A bottom plate, such as the end plate 20 shown in FIG. 3, FIG. 10 to FIG. 13 disclose a field port closure device 300 according to the present invention, which is designed to provide a container 1 for the container 1 0 dyke 4 closed. The Fukou Closer 300 also provides a radon-free and gas-permeable shield. The port closure device 3 0 generally includes a communication element 3 2, a blocking element 3 04, a covering element 3 06 and a cuff 3 0 8. The communication element 3 02 is typically in the form of a hose. The hose 3 0 2 is typically made from an elastic material such as silicon. The size of this hose can be changed depending on the particular application. In a preferred embodiment, a 3/4 inch hose is used. The hose 300 has a first end and a second end, and the length of the hose is determined by the desired application. The blocking element 3 0 4 is typically of the type of a plug 3 0 4. The plug 304 is typically cylindrical and is selected from a breathable but water-repellent material such that it allows gas such as air to pass through, but prevents liquid from flowing out of the plug 304. In a preferred embodiment, the plug 304 is made from a breathable elastic material such as polyethylene. Polytetrafluoroethylene materials can also be used. Other materials are also possible, and materials that are water-repellent after processing can also be used. The pore size of the material is defined so that it can provide a gas-permeable, sterile shield. In a preferred embodiment, the plug is a commercially available porex® drainage material. The embolism · 3 0 4 is roughly approximated! It is inch long and has a diameter-defining dimension so that when it is inserted into an end of the hose 302, it will form an interference fit. If it is further displayed in the drawing 〇 (Please read the precautions on the back before filling this page) ________ ^ _________. ··
1225461 A7 ____B7____ 五、發明說明（J ) 至圖1 2中，該覆蓋元件3 Ο 6具有一個第一元件3 1 ο 和一第二元件3 1 2。該元件3 1 0、3 1 2可由玻璃紙 或紙製造。除此之外，其中一個元件可以是紙，而另一個 元件則爲玻璃紙。如在下文將有更詳細的說明，該元件3 1 0、3 1 2係彼此互相密封以形成一種兩股、可剝除的 囊袋，其具有一開口以接收該軟管3 0 2的第二末端。該 箍帶3 0 8典型地亦爲彈性材料所製成’諸如矽樹脂’且 可從與使用在璋口封閉器3 0 0之中的管相同的管材所裁 切。 如進一步顯示在圖1 2中，在構建並且將該璋口封閉 器連接至該容器1 0中，該軟管3 0 2首先係被裁切成所 想要的長度，例如6-30呎的管子。該軟管3 0 2的一第一 末端3 1 4係穿透過該容器1 0上的璋口4 0以形成一種 干涉配合。一繩帶可以置放在該軟管3 〇 2之第一末端3 1 4的周圍，當其係安裝在該埠口 4 〇上時’以更穩固地 將該軟管3 0 2連接在該璋口 4 0上方。在繃緊之後’該 繩帶3 1 6於是被裁切。該栓塞3 0 4係從合適的栓材切 割成一吋長。如顯示在圖1 0和圖1 1中，該栓塞3 0 4 隨後係***在該軟管3 0 2的一個第二末端3 1 8 °該栓 塞3 0 4的一部分從該軟管3 0 2的第二末端延伸出’以 容許操作者可抓住該栓塞3 0 4，而從該軟管3 〇 2移除 之。該覆蓋元件3 0 6的第一元件3 1 〇和第二元件3 1 2彼此互相密封，但是留下一開口末端3 2 0 (圖1 2 ) 以形成一囊袋3 2 2。該覆蓋元件3 〇 6隨後係安置在該 20 本紙張尺度適用中國國家標準（CNS)A4規格（210 X 297公釐） (請先閱讀背面之注意事項再填寫本頁)1225461 A7 ____B7____ 5. Description of the invention (J) to FIG. 12, the covering element 3 0 6 has a first element 3 1 ο and a second element 3 1 2. The elements 3 1 0, 3 1 2 can be made of cellophane or paper. In addition, one component can be paper and the other component is cellophane. As will be explained in more detail below, the elements 3 1 0, 3 1 2 are sealed to each other to form a two-stranded, peelable pouch that has an opening to receive the first 3 2 2 of the hose. Both ends. The cuff 3 08 is also typically made of an elastic material 'such as silicone' and can be cut from the same tube as the tube used in the mouthpiece sealer 300. As further shown in FIG. 12, after constructing and connecting the mouthpiece sealer to the container 10, the hose 3 0 2 is first cut to a desired length, such as 6-30 feet. tube. A first end 3 1 4 of the hose 3 2 is passed through the mouth 40 of the container 10 to form an interference fit. A strap can be placed around the first end 3 1 4 of the hose 3 02 when it is attached to the port 4 0 'to connect the hose 3 2 to the hose more securely. Pass above 40. After tightening 'the strap 3 1 6 is then cut. The plug 304 was cut from a suitable plug material to an inch length. As shown in FIGS. 10 and 11, the plug 3 0 4 is then inserted at a second end of the hose 3 2 3 1 8 ° a part of the plug 3 0 4 is removed from the hose 3 0 2 The second end of the tube extends' to allow the operator to grasp the plug 304 and remove it from the hose 3002. The first element 3 10 and the second element 3 1 2 of the covering element 3 06 are sealed to each other, but an open end 3 2 0 (FIG. 12) is left to form a pouch 3 2 2. The covering element 3 06 was subsequently placed on the 20 paper size to apply Chinese National Standard (CNS) A4 (210 X 297 mm) (Please read the precautions on the back before filling this page)
裝---I ·111111. 1225461 A7 ___— B7__ 五、發明說明（θ ) 軟管3 0 2的第二末端3 1 8和栓塞3 0 4上。該箍帶3 0 8隨後係置於該覆蓋元件3 0 6和該軟管3 0 2上以將 該覆蓋元件3 0 6固定到軟管3 0 2。因爲該彈性的箍帶 3 0 8係從相同於軟管3 0 2的管材所裁切，當該箍帶3 0 8係定置在該軟管3 0 2周圍時，其提供了一徑向壓縮 力於覆蓋元件3 0 6上，逆對著軟管3 0 2。該覆蓋元件 3 0 6提供一防塵蓋，因此如果該軟管3 0 2的第二末端 3 1 8不慎地掉落在地上或者其它的觸碰污染，該透氣的 栓塞3 0 4和該軟管末端3 1 8仍保持淸潔和無菌。如果 想要修飾成另一種特點，該覆蓋元件3 0 6可使用一種無 法移除的附接件，諸如一收縮帶3 0 9 (圖1 1 )而永久 地固定到該軟管3 0 2的第二末端3 1 8。 有兩種一般性的方法存取在該軟管3 0 2的第二末端 處的栓塞3 0 4。如顯示在圖1 〇之中，該第一元件3 1 ◦和第二元件3 1 2的頂部邊緣3 2 4可被剝離以開啓該 覆蓋元件3 0 6。或者如顯示在圖1 1之中，該箍帶3 〇 8可以滾下該軟管3 0 2和該覆蓋元件3 0 6而從該軟管 3 0 2的第二末端拉開。在任何一種情況之中，一旦該覆 蓋元件被移除之後，該栓塞3 0 4亦可被移除，其中該液 體可以從該容器1 0被排放或者抽取。 在某種例子中，一個容器可能具有複數個埠口，例如 一塡充埠口、一排放埠口以及一排氣埠□。圖1 3揭露一 容器1 0，其具有一額外的埠口 3 3 0，該埠口 3 3 0藉 由一排氣封閉器3 3 2所關閉。該排氣封閉器3 3 2係相 21 本紙張尺度^"中國國家標準（CNS)A4規格（210><297公釐） ^ ' (請先閱讀背面之注意事項再填寫本頁) ----訂---------. 1225461 A7 B7 - 一 _ ^ — , , ' .......- 1 - 五、發明說明（，） 似於上述的埠口封閉器3 0 0。該排氣封閉器3 3 2具有 一短矽管3 3 4，其一端係連接至該頟外的璋口 3 3〇。 一個從與捧口關閉氣栓塞3 0 4相同的材料所製成的排氣 栓塞3 3 6係被***於該管3 3 4的自由末端之中。該排 氣栓塞3 3 6容許氣體通過其本身以將容器1 〇內部的壓 力與容器1 0外部的壓力均等化。該排氣栓塞3 3 6使得 該容器10能夠完全塡充並且伴隨有頂端空間（也就是該 液體高度和該容器頂部之空間）之減少。此係爲固定容器 應用之中的一項優點，因爲無法控制的頂端空間可造成在 液體中的氣體濃度之改變’因此容許液體中的PH値的改 變。在一欲被運送的容器1 0中，頂端空間係爲一種特別 關鍵的問題，因爲頂端空間將容許在運送期間液體的擾動 。此種液體運動可能因爲變性作用（發泡）而造成液體中 蛋白質的減少，以及包含容器其本身因爲反覆的機械應力 (撓曲開裂）。 如進一步的顯示在圖1 3之中，如果需要的話’一閥 門3 3 8 (或者是連通兀件）可以被置放在管3 3 4之中 ，介於該第一末端和第二末端之間。該閥門3 3 8 ’諸如 一旋塞閥或者其它合適的閥’可被開啓或者關閉以容許或 者防止該容器1 0的排氣，視需要決定。舉例而言’該閥 門3 3 8可被開啓，以在塡充的最後階段期間將容器1 〇 排氣。相反地，該閥門可被關閉，例如在運送或者排放期 間時。 本發明的埠口關閉器3 0 0提供數種優點，也就是提 22 尺 票準（CNS)A4 規格（210 x 297 公$ "~~^ (請先閱讀背面之注意事項再填寫本頁) 1!裝 1225461 A7 ___B7 ___ 五、發明說明（) 供一種無菌但是仍具有氣透性的關閉器。該無菌防護體防 止污染。該關閉器3 0 0的可滲透性均衡了該軟管3 〇 2 之中的內部壓力、以及與該軟管連通的谷器1 〇，和該谷 器10周圍的外部壓力。壓力平衡容許無菌空氣進入該容 器1〇，其促進了該容器1〇在操作和安裝期間的操作。 舉例而言，壓力均等容許該大的、撓性的、可折疊的容器 1 0於淨空時可簡單地操作，而不會有導入非無菌的空氣 的風險。在操作和安裝期間在容器1〇中具有空氣是必要 的，因爲空氣作爲一種容許容器板片獨立地移動的潤滑作 用。然而，在消毒和運送期間在容器1〇中具有空氣會使 得容器1 〇膨脹。容器膨脹係不理想的並且會減小最大可 能程度。因此，較爲理想的是運送塡充有流體但儘可能具 有少量空氣的容器，並且容許空氣進入容器1 0而不會侵 害無菌性。該無菌、氣體可滲透的埠口封閉器提供此種優 點。如果該軟管3 0 2的第二末端3 1 8意外地掉落或者 導入至污染物時，該覆蓋元件3 0 6保持該軟管3 0 2的. 第二末端3 1 8和栓塞3 0 4無菌。除此之外，該埠口封 閉器3 0 0不需要噴射鑄造的埠口或者不銹鋼的聯結件， 因此可節省成本。此外，藉由使用干涉配合於該軟管3 〇 2和栓塞3 0 4之間，不需要溶劑以將該栓塞連接至軟管 3〇2，因此減少進入該容器1 0可濾取的量。 其可以瞭解的是，所給予的本發明之實施例之說明， 不同的修飾可由熟悉此項技藝人士達成。此種修飾應包含 在以下之申請專利範圍之中。 23 本紙張尺度適用中國國家標f(CNS)A4規格（210 X 297公釐) ^ ~~一 (請先閱讀背面之注意事項再填寫本頁)Installation --- I · 111111. 1225461 A7 ___- B7__ V. Description of the invention (θ) The second end of the hose 3 0 2 3 1 8 and the plug 3 0 4. The cuff 3 0 8 is then tied to the covering element 3 06 and the hose 3 2 2 to secure the covering element 3 0 6 to the hose 3 2. Because the elastic cuff 3 0 8 is cut from the same tube as the tube 3 2 0, when the cuff 3 8 is positioned around the tube 3 2 2, it provides a radial compression Apply force on the cover element 3 06, facing the hose 3 02. The covering element 3 0 6 provides a dust cover, so if the second end 3 1 8 of the hose 3 2 accidentally falls to the ground or other touch pollution, the breathable plug 3 0 4 and the soft The end of the tube 3 1 8 remains clean and sterile. If it is desired to modify it to another characteristic, the covering element 3 0 6 can be permanently fixed to the hose 3 0 2 using a non-removable attachment, such as a shrink band 3 9 (Figure 1 1). Second end 3 1 8. There are two general ways to access the plug 3 04 at the second end of the hose 3 02. As shown in FIG. 10, the top edge 3 2 4 of the first element 3 1 ◦ and the second element 3 1 2 can be peeled off to open the covering element 3 06. Alternatively, as shown in FIG. 11, the cuff 3 08 can be rolled off the hose 30 2 and the covering element 3 06 and pulled away from the second end of the hose 3 02. In either case, once the covering element is removed, the plug 304 can also be removed, wherein the liquid can be discharged or drawn from the container 10. In some cases, a container may have multiple ports, such as a charge port, a discharge port, and an exhaust port. Figure 13 discloses a container 10 having an additional port 3 3 0, which is closed by an exhaust closure 3 3 2. The exhaust obturator 3 3 2 series phase 21 paper size ^ " Chinese National Standard (CNS) A4 Specification (210 > < 297 mm) ^ '(Please read the precautions on the back before filling this page)- --- Order ---------. 1225461 A7 B7-One _ ^ —,, '.......- 1-V. Description of the invention (,) Similar to the port sealer described above 3 0 0. The exhaust obturator 3 3 2 has a short silicon tube 3 3 4, one end of which is connected to the mouth 3 3 0 outside the mouth. An exhaust plug 3 3 6 made of the same material as the mouthpiece closing gas plug 3 0 4 is inserted into the free end of the tube 3 3 4. The exhaust plug 3 3 6 allows gas to pass through itself to equalize the pressure inside the container 10 and the pressure outside the container 10. The vent plug 3 3 6 enables the container 10 to be fully filled with a reduction in headspace (i.e., the height of the liquid and the space at the top of the container). This is an advantage in stationary container applications because the uncontrolled headspace can cause a change in the gas concentration in the liquid ' and thus allows for a change in the pH of the liquid. In a container 10 to be transported, the headspace is a particularly critical issue, as the headspace will allow the disturbance of liquids during transport. This fluid movement may result in a decrease in protein in the fluid due to denaturation (foaming) and contain the container itself due to repeated mechanical stress (flexural cracking). As further shown in FIG. 13, if necessary, a valve 3 3 8 (or a connecting element) can be placed in the tube 3 3 4 between the first end and the second end. between. The valve 3 3 8 ', such as a plug valve or other suitable valve', can be opened or closed to allow or prevent venting of the container 10, as needed. For example, 'the valve 3 3 8 may be opened to evacuate the container 10 during the final stage of charging. Conversely, the valve can be closed, for example during shipping or discharge. The port closer 3 0 of the present invention provides several advantages, that is, the 22-foot ticket (CNS) A4 specification (210 x 297) $ " ~~ ^ (Please read the precautions on the back before filling this page ) 1! Pack 1225461 A7 ___B7 ___ 5. Description of the invention () Provide a sterile but still air-permeable closing device. The sterile protective body prevents contamination. The permeability of the closing device 3 0 0 equalizes the hose 3 The internal pressure in 〇2, and the trough device 10 communicating with the hose, and the external pressure around the trough device 10. The pressure balance allows sterile air to enter the container 10, which promotes the operation of the container 10 And operation during installation. For example, the equal pressure allows the large, flexible, foldable container 10 to be easily operated with clear headroom without the risk of introducing non-sterile air. During operation and It is necessary to have air in the container 10 during installation, because air serves as a lubricating effect that allows the container plates to move independently. However, having air in the container 10 during sterilization and shipping causes the container 10 to expand. The container Expansion system It is not ideal and will reduce the maximum possible degree. Therefore, it is more desirable to transport a container filled with fluid but having as little air as possible, and allow air to enter the container 10 without compromising sterility. The sterility, gas A permeable port closer provides this advantage. The cover element 3 0 6 holds the hose 3 0 2 if the second end 3 1 8 of the hose 3 2 accidentally drops or is introduced into a contaminant. The second end 3 1 8 and the plug 3 0 4 are sterile. In addition, the port sealer 3 0 0 does not require spray-cast port or stainless steel couplings, thus saving costs. In addition, by Using an interference fit between the hose 300 and the plug 304, no solvent is needed to connect the plug to the hose 300, thus reducing the amount that can be filtered out into the container 10. It can be understood Yes, given the description of the embodiments of the present invention, different modifications can be achieved by those skilled in the art. Such modifications should be included in the scope of patent applications below. 23 This paper standard applies to the Chinese national standard f (CNS) A4 size (210 X 297 mm) ^ ~~ 一 (Please read the notes on the back before filling this page)