TW274051B - - Google Patents

Info

Publication number
TW274051B
TW274051B TW081109085A TW81109085A TW274051B TW 274051 B TW274051 B TW 274051B TW 081109085 A TW081109085 A TW 081109085A TW 81109085 A TW81109085 A TW 81109085A TW 274051 B TW274051 B TW 274051B
Authority
TW
Taiwan
Application number
TW081109085A
Original Assignee
Hemagen Pfc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hemagen Pfc filed Critical Hemagen Pfc
Application granted granted Critical
Publication of TW274051B publication Critical patent/TW274051B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
TW081109085A 1991-11-13 1992-11-13 TW274051B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/791,420 US5304325A (en) 1991-11-13 1991-11-13 Emulsions containing alkyl- or alkylglycerophosphoryl choline surfactants and methods of use

Publications (1)

Publication Number Publication Date
TW274051B true TW274051B (zh) 1996-04-11

Family

ID=25153664

Family Applications (1)

Application Number Title Priority Date Filing Date
TW081109085A TW274051B (zh) 1991-11-13 1992-11-13

Country Status (9)

Country Link
US (3) US5304325A (zh)
EP (1) EP0663829A1 (zh)
JP (1) JPH07501263A (zh)
CN (1) CN1072593A (zh)
AU (1) AU661535B2 (zh)
CA (1) CA2121502A1 (zh)
IL (1) IL103722A (zh)
TW (1) TW274051B (zh)
WO (1) WO1993009787A1 (zh)

Families Citing this family (47)

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US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) * 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5304325A (en) * 1991-11-13 1994-04-19 Hemagen/Pfc Emulsions containing alkyl- or alkylglycerophosphoryl choline surfactants and methods of use
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6395494B1 (en) 1993-05-13 2002-05-28 Neorx Corporation Method to determine TGF-β
US6306421B1 (en) 1992-09-25 2001-10-23 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5770609A (en) * 1993-01-28 1998-06-23 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6663881B2 (en) * 1993-01-28 2003-12-16 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5595722A (en) * 1993-01-28 1997-01-21 Neorx Corporation Method for identifying an agent which increases TGF-beta levels
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5695740A (en) * 1993-05-12 1997-12-09 The Board Of Regents Of The University Of Nebraska Perfluorocarbon ultrasound contrast agent comprising microbubbles containing a filmogenic protein and a saccharide
US5701899A (en) * 1993-05-12 1997-12-30 The Board Of Regents Of The University Of Nebraska Perfluorobutane ultrasound contrast agent and methods for its manufacture and use
US6197789B1 (en) 1995-06-07 2001-03-06 Neorx Corporation Prevention and treatment of cardiovascular pathologies with tamoxifen analogues
CA2162586C (en) * 1993-05-13 2006-01-03 David J. Grainger Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells
FR2710840B1 (fr) * 1993-10-04 1995-12-01 Applic Transferts Technolo Compositions viscoélastiques hautement concentrées en composés fluorés, leur préparation et leurs utilisations dans le domaine médical et en cosmétique.
AU2245295A (en) * 1994-04-15 1995-11-10 Hemagen/Pfc Fluorochemical emulsions containing 1,3-dialkylglycerophosphoryl choline surfactants and methods of use
JP3839857B2 (ja) * 1994-09-20 2006-11-01 塩野義製薬株式会社 エーテル型チオリン脂質化合物の製造方法
IL115693A (en) * 1994-10-25 2000-08-13 Revlon Consumer Prod Corp Cosmetic compositions with improved transfer resistance
US5804162A (en) 1995-06-07 1998-09-08 Alliance Pharmaceutical Corp. Gas emulsions stabilized with fluorinated ethers having low Ostwald coefficients
US5733526A (en) * 1995-12-14 1998-03-31 Alliance Pharmaceutical Corp. Hydrocarbon oil/fluorochemical preparations and methods of use
US5840276A (en) * 1996-01-11 1998-11-24 Apfel Enterprises, Inc. Activatable infusable dispersions containing drops of a superheated liquid for methods of therapy and diagnosis
US6245747B1 (en) 1996-03-12 2001-06-12 The Board Of Regents Of The University Of Nebraska Targeted site specific antisense oligodeoxynucleotide delivery method
US5849727A (en) 1996-06-28 1998-12-15 Board Of Regents Of The University Of Nebraska Compositions and methods for altering the biodistribution of biological agents
US5834519A (en) * 1996-10-11 1998-11-10 Wayne State University Stabilized gas-supersaturated emulsions and suspensions
US5980936A (en) * 1997-08-07 1999-11-09 Alliance Pharmaceutical Corp. Multiple emulsions comprising a hydrophobic continuous phase
AU3477300A (en) * 1999-02-03 2000-08-25 Supergen, Inc. Phosphocholine surfactants and their use
US7220401B2 (en) * 1999-09-24 2007-05-22 Barnes-Jewish Hospital Blood clot-targeted nanoparticles
US6676963B1 (en) * 2000-10-27 2004-01-13 Barnes-Jewish Hospital Ligand-targeted emulsions carrying bioactive agents
WO2003062198A1 (en) 2002-01-24 2003-07-31 Barnes Jewish Hospital Integrin targeted imaging agents
US20040126400A1 (en) * 2002-05-03 2004-07-01 Iversen Patrick L. Delivery of therapeutic compounds via microparticles or microbubbles
CA2569461A1 (en) 2004-06-09 2005-12-29 Kereos, Inc. Lipophilic derivatives of chelate monoamides
US20070258908A1 (en) * 2006-04-27 2007-11-08 Lanza Gregory M Detection and imaging of target tissue
US20090048423A1 (en) * 2007-08-15 2009-02-19 Tyco Healthcare Group Lp Phospholipid Copolymers
WO2009049083A1 (en) 2007-10-09 2009-04-16 Washington University In St. Louis Particles for imaging
US9468607B2 (en) 2007-10-09 2016-10-18 Washington University Ligand directed toroidal nanoparticles for therapy and diagnostic imaging
JP2013514999A (ja) 2009-12-17 2013-05-02 ワシントン・ユニバーシティ 抗血栓性ナノ粒子
US9808500B2 (en) 2009-12-17 2017-11-07 Washington University Antithrombotic nanoparticle
MX2012010769A (es) * 2010-03-19 2013-02-27 Oxygen Biotherapeutics Inc Formulaciones perfluorocarbonadas oftalmicas en forma de crema.
CN103096874A (zh) 2010-04-15 2013-05-08 华盛顿大学 前药组合物、前药纳米粒子及其使用方法
WO2012112796A2 (en) * 2011-02-16 2012-08-23 Oxygen Biotherapeutics, Inc. Perfluoro(n-butylcyclohexane) compositions and uses thereof
FR2980364B1 (fr) 2011-09-26 2018-08-31 Guerbet Nanoemulsions et leur utilisation comme agents de contraste
FR2980365B1 (fr) 2011-09-26 2016-02-12 Guerbet Sa Nanoemulsions, leur procede de preparation, et leur utilisation comme agent de contraste.
CN103127876B (zh) * 2011-11-22 2015-01-07 中国科学院大连化学物理研究所 一种季胺化有机膦表面活性剂及其合成方法
US9095521B2 (en) 2012-02-02 2015-08-04 Washington University Methods for improving muscle strength
EP3285818B1 (en) * 2015-04-24 2020-09-23 Lubrizol Advanced Materials, Inc. Surface modified polymer compositions
US10213448B2 (en) 2016-03-25 2019-02-26 Novazoi Theranostics Ethanolamine-based lipid biosynthetic compounds, method of making and use thereof

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US3911138B1 (en) * 1973-02-26 1996-10-29 Childrens Hosp Medical Center Artificial blood and method for supporting oxygen transport in animals
US4159988A (en) * 1974-08-06 1979-07-03 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Synthetic phospholipids, a process for their manufacture and their use
US4110474A (en) * 1977-08-26 1978-08-29 Suntech, Inc. Tetramethylpentane blood substitutes
US4187252A (en) * 1977-08-26 1980-02-05 Suntech, Inc. Tetramethylpentane blood substitutes
US4252827A (en) * 1979-05-23 1981-02-24 The Green Cross Corporation Oxygen-transferable fluorocarbon emulsion
US4443480A (en) * 1982-04-12 1984-04-17 Children's Hospital Medical Center Artificial blood and other gas transport agents
JPS5916495A (ja) * 1982-07-19 1984-01-27 Sanyo Electric Co Ltd スピ−カ振動板とエツジとの接合方法
US4423077A (en) * 1982-07-27 1983-12-27 The University Of Pennsylvania Perfluorochemical emulsion artificial blood
US4534978A (en) * 1982-12-28 1985-08-13 The Green Cross Corporation Perfluorocycloamines
SE8505048L (sv) * 1985-10-25 1987-04-26 Nutritional Int Res Inst Nutritionsemulsion med syretransporterande egenskaper
ES2054658T3 (es) * 1986-01-24 1994-08-16 Childrens Hosp Medical Center Metodo para la preparacion de una emulsion fisiologicamente aceptable.
EP0262876B1 (en) * 1986-09-27 1992-04-29 Toyo Jozo Kabushiki Kaisha Nucleoside-phospholipid conjugate
US4781676A (en) * 1987-02-20 1988-11-01 Air Products And Chemicals, Inc. Interstitial administration of perfluorochemical emulsions for reoxygenation of hypoxic tumor cells
US4895876A (en) * 1987-03-20 1990-01-23 Air Products And Chemicals, Inc. Concentrated stable fluorochemical aqueous emulsions containing triglycerides
US5061484A (en) * 1988-03-11 1991-10-29 Alpha Therapeutic Corporation Perfluorochemical emulsion with stabilized vesicles
US5171755A (en) * 1988-04-29 1992-12-15 Hemagen/Pfc Emulsions of highly fluorinated organic compounds
JPH0667818B2 (ja) * 1988-06-20 1994-08-31 花王株式会社 半透明乳化化粧料
US4996041A (en) * 1988-08-19 1991-02-26 Toshiyuki Arai Method for introducing oxygen-17 into tissue for imaging in a magnetic resonance imaging system
US5114703A (en) * 1989-05-30 1992-05-19 Alliance Pharmaceutical Corp. Percutaneous lymphography using particulate fluorocarbon emulsions
CH677886A5 (zh) * 1989-06-26 1991-07-15 Hans Georg Prof Dr Weder
DE3943000A1 (de) * 1989-12-27 1991-07-04 Medmark Pharma Gmbh Verfahren zur herstellung von glycerinderivaten
US5306508A (en) * 1990-06-22 1994-04-26 The Regents Of The University Of California Red blood cell surrogate
US5304325A (en) * 1991-11-13 1994-04-19 Hemagen/Pfc Emulsions containing alkyl- or alkylglycerophosphoryl choline surfactants and methods of use
US5262442A (en) * 1991-12-24 1993-11-16 Alpha Therapeutic Corporation Process for rapid thawing and storage of frozen fluorocarbon emulsion, and resultant product

Also Published As

Publication number Publication date
WO1993009787A1 (en) 1993-05-27
AU661535B2 (en) 1995-07-27
US5304325A (en) 1994-04-19
EP0663829A1 (en) 1995-07-26
IL103722A (en) 1997-03-18
US5439669A (en) 1995-08-08
AU3135893A (en) 1993-06-15
IL103722A0 (en) 1993-04-04
CA2121502A1 (en) 1993-05-27
US5439944A (en) 1995-08-08
CN1072593A (zh) 1993-06-02
JPH07501263A (ja) 1995-02-09

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