TW221688B - - Google Patents

Info

Publication number: TW221688B
Authority: TW; Taiwan

Application number

TW081110390A

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-12-30

Filing date

1992-12-28

Publication date

1994-03-11

1992-12-28 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

1994-03-11 Application granted granted Critical

1994-03-11 Publication of TW221688B publication Critical patent/TW221688B/zh

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/42—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms with nitro or nitroso radicals directly attached to ring carbon atoms
- C07D333/44—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms with nitro or nitroso radicals directly attached to ring carbon atoms attached in position 5

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

TW081110390A 1991-12-30 1992-12-28 TW221688B (zh)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP91203431		1991-12-30

Publications (1)

Publication Number	Publication Date
TW221688B true TW221688B (zh)	1994-03-11

Family

ID=8208119

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TW081110390A TW221688B (zh)	1991-12-30	1992-12-28

Country Status (16)

Country	Link
US (5)	US5480997A (zh)
EP (1)	EP0620811A1 (zh)
JP (1)	JPH07502523A (zh)
CN (1)	CN1034074C (zh)
AP (1)	AP392A (zh)
AU (1)	AU658260B2 (zh)
CA (1)	CA2125675A1 (zh)
FI (1)	FI943119A (zh)
HU (1)	HUT70515A (zh)
IL (1)	IL104257A (zh)
MX (1)	MX9207619A (zh)
NO (1)	NO942480L (zh)
PH (1)	PH30258A (zh)
TW (1)	TW221688B (zh)
WO (1)	WO1993013069A1 (zh)
ZA (1)	ZA9210078B (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5587387A (en) *	1991-12-30	1996-12-24	Janssen Pharmaceutica N.V.	Heterocycle-substituted benzenemethanamine derivatives
US5767310A (en) *	1993-03-19	1998-06-16	Merck & Co., Inc.	Phenoxyphenylacetic acid derivatives
US5686478A (en) *	1993-07-20	1997-11-11	Merck & Co. Inc.	Endothelin antagonists
US5559135A (en) *	1994-09-14	1996-09-24	Merck & Co., Inc.	Endothelin antagonists bearing pyridyl amides
US5538991A (en) *	1994-09-14	1996-07-23	Merck & Co., Inc.	Endothelin antagonists bearing 5-membered heterocyclic amides
GB0016787D0 (en)	2000-07-07	2000-08-30	Pfizer Ltd	Compounds useful in therapy

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3274190A (en) *		1966-09-20		Hydroxyphenethyl-amino-s-triazine
ES368093A1 (es) *	1968-07-16	1971-07-16	Degussa	Procedimiento para la preparacion de bencilaminas n-hetero-ciclicamente sustituidas.
US4246429A (en) *	1978-06-23	1981-01-20	Janssen Pharmaceutica, N.V.	Novel α-amino-phenylacetic acid derivatives
US5407960A (en) *	1989-12-22	1995-04-18	Schering Corporation	Mercaptocycloacyl aminoacid endopeptidase inhibitors
EP0507861B1 (en) *	1989-12-28	1996-09-11	The Upjohn Company	Diaromatic substituted anti-aids compounds

1992
- 1992-12-14 PH PH45418A patent/PH30258A/en unknown
- 1992-12-22 AU AU32580/93A patent/AU658260B2/en not_active Ceased
- 1992-12-22 CA CA002125675A patent/CA2125675A1/en not_active Abandoned
- 1992-12-22 US US08/240,737 patent/US5480997A/en not_active Expired - Fee Related
- 1992-12-22 JP JP5511436A patent/JPH07502523A/ja active Pending
- 1992-12-22 WO PCT/EP1992/002993 patent/WO1993013069A1/en not_active Application Discontinuation
- 1992-12-22 HU HU9401380A patent/HUT70515A/hu unknown
- 1992-12-22 EP EP93901757A patent/EP0620811A1/en not_active Withdrawn
- 1992-12-28 TW TW081110390A patent/TW221688B/zh active
- 1992-12-29 MX MX9207619A patent/MX9207619A/es unknown
- 1992-12-29 ZA ZA9210078A patent/ZA9210078B/xx unknown
- 1992-12-29 AP APAP/P/1992/000468A patent/AP392A/en active
- 1992-12-29 CN CN92115151A patent/CN1034074C/zh not_active Expired - Fee Related
- 1992-12-29 IL IL10425792A patent/IL104257A/en not_active IP Right Cessation
1994
- 1994-06-29 FI FI943119A patent/FI943119A/fi not_active Application Discontinuation
- 1994-06-30 NO NO942480A patent/NO942480L/no unknown
1995
- 1995-05-02 US US08/432,751 patent/US5552430A/en not_active Expired - Fee Related
- 1995-05-02 US US08/433,910 patent/US5550135A/en not_active Expired - Fee Related
- 1995-05-02 US US08/432,750 patent/US5604230A/en not_active Expired - Fee Related
- 1995-05-02 US US08/432,757 patent/US5541215A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
PH30258A (en)	1997-02-05
HUT70515A (en)	1995-10-30
CA2125675A1 (en)	1993-07-08
CN1034074C (zh)	1997-02-19
AU3258093A (en)	1993-07-28
JPH07502523A (ja)	1995-03-16
HU9401380D0 (en)	1994-08-29
MX9207619A (es)	1993-06-01
NO942480D0 (no)	1994-06-30
US5604230A (en)	1997-02-18
CN1073942A (zh)	1993-07-07
AP9200468A0 (en)	1993-01-31
FI943119A0 (fi)	1994-06-29
EP0620811A1 (en)	1994-10-26
NO942480L (no)	1994-06-30
US5541215A (en)	1996-07-30
US5552430A (en)	1996-09-03
IL104257A (en)	1996-12-05
AP392A (en)	1995-08-03
ZA9210078B (en)	1994-06-29
WO1993013069A1 (en)	1993-07-08
FI943119A (fi)	1994-06-29
IL104257A0 (en)	1993-05-13
AU658260B2 (en)	1995-04-06
US5550135A (en)	1996-08-27
US5480997A (en)	1996-01-02

Publication	Publication Date	Title
EP0553570A3 (zh)	1995-07-19
DK0498143T3 (zh)	1997-03-03
EP0534437A3 (zh)	1995-03-08
EP0543465A3 (zh)	1995-04-12
TW221688B (zh)	1994-03-11
FR2681097B1 (zh)	1995-04-07
DE4290735T1 (zh)	1993-04-01
FR2683219B1 (zh)	1995-01-27
FR2675000B1 (zh)	1994-11-25
FR2679969B1 (zh)	1997-02-28
FR2673952B1 (zh)	1995-05-12
FR2682578B1 (zh)	1995-06-02
FR2679724B1 (zh)	1994-12-23
FR2685123B1 (zh)	1997-02-28
FR2687883B1 (zh)	1995-03-31
ECSM91533U (zh)	1991-11-04
GB9122450D0 (zh)	1991-12-04
ECSM91556U (zh)	1992-03-27
ECSDI910045S (zh)	1992-05-25
EP0511858A3 (zh)	1995-02-15
EP0533351A3 (zh)	1994-01-19
EP0501346A3 (zh)	1994-03-09
EP0550072A3 (zh)	1994-02-09
EP0549908A3 (zh)	1994-01-26
EP0517407A3 (zh)	1994-03-23