TW202021639A

TW202021639A - Sunscreen effect enhancer

Info

Publication number: TW202021639A
Application number: TW108128603A
Authority: TW
Inventors: 氏本慧; 永禮由布子; 長井宏一; 瑪麗安彩香東亞智; 八巻悟史
Original assignee: 日商資生堂股份有限公司
Priority date: 2018-08-10
Filing date: 2019-08-12
Publication date: 2020-06-16
Also published as: JP2024041892A; JPWO2020032246A1; WO2020032246A1

Abstract

The present invention addresses the problem of developing an additive that makes it possible to provide an ideal sunscreen cosmetic of which the UV protective ability is improved by heating. An additive for enhancing the UV protective effect of a sunscreen cosmetic by heating, the additive being characterized by including at least one selected from the group consisting of amphiphilic substances or moisturizers having an IOB value of 5.0 or lower. The amphiphilic substance or moisturizer is preferably a polyoxyalkylene-polyoxyethylene copolymer dialkyl ether and/or polyhydric alcohol.

Description

防曬效果增強劑Sunscreen enhancer

本發明係關於一種用以增強防曬效果之添加劑。更詳細而言，係關於一種防曬化妝料用添加劑，該防曬化妝料用添加劑若添加於含有紫外線吸收劑或紫外線散射劑之防曬化妝料中，則可賦予紫外線防禦效果藉由加熱而提昇之新穎特性。The present invention relates to an additive for enhancing sun protection effect. More specifically, it relates to an additive for sunscreen cosmetics. The additive for sunscreen cosmetics, if added to sunscreen cosmetics containing ultraviolet absorbers or ultraviolet scattering agents, can impart a novel novelty that the ultraviolet protection effect is enhanced by heating characteristic.

具有防曬效果之化妝料藉由調配於化妝料中之紫外線吸收劑或紫外線散射劑之作用，降低到達至塗抹有該化妝料之皮膚之紫外線量，藉此抑制對皮膚之不良影響。The cosmetics with sunscreen effect reduce the amount of ultraviolet rays that reach the skin coated with the cosmetics through the action of the ultraviolet absorber or ultraviolet scattering agent formulated in the cosmetics, thereby suppressing adverse effects on the skin.

作為防曬化妝料之紫外線防禦效果之指標，最廣泛已知有防曬係數(Sun Protection Factor：SPF)，以SPF值(例如「SPF30」等)表示紫外線防禦效果。於日本，對UVA區域之紫外線使用PFA(Protection Factor of UVA，UVA防禦係數)或UVAPF(UVA Protection factor of product，製品之UVA防禦係數)，以基於PFA或UVAPF之值的PA(Protection grade of UVA，UVA防禦等級)分類(「PA++」等)表示製品之UVA防禦效果之程度。於美國，使用表示UVA與UVB之防禦效果之平衡之臨界波長(Critical Wavelength：CW)。As an indicator of the UV protection effect of sunscreen cosmetics, the sun protection factor (SPF) is the most widely known, and the UV protection effect is represented by the SPF value (for example, "SPF30", etc.). In Japan, PFA (Protection Factor of UVA, UVA defense factor) or UVAPF (UVA Protection factor of product) is used for ultraviolet rays in the UVA region, and PA (Protection grade of UVA) is based on the value of PFA or UVAPF. , UVA defense level) classification ("PA++", etc.) indicates the degree of UVA defense effect of the product. In the United States, Critical Wavelength (CW), which represents the balance of the defensive effects of UVA and UVB, is used.

近年來，為了抑制由紫外線所引起之對皮膚之不良影響，要求於UVA至UVB之廣泛之波長區域發揮較高之紫外線防禦效果之化妝料，例如市售有宣稱SPF50以上(50+)及PA++++之防曬製品。In recent years, in order to suppress the harmful effects of ultraviolet rays on the skin, cosmetics with high UV protection effects in a wide range of wavelengths from UVA to UVB are required. For example, there are commercially available cosmetics that claim SPF50 or higher (50+) and PA++++ The sunscreen products.

由防曬製品所產生之紫外線防禦效果係由調配之紫外線吸收劑或紫外線散射劑而發揮，但於紫外線吸收劑中有紫外線吸收能力因光照射而降低者，另一方面，亦有因與水分接觸，紫外線吸收劑或散射劑流出而防禦能力降低之情況。The ultraviolet protection effect produced by sunscreen products is exerted by the formulated ultraviolet absorbers or ultraviolet scattering agents. However, among the ultraviolet absorbers, the ultraviolet absorption capacity is reduced by light irradiation. On the other hand, it is also caused by contact with moisture. , When the UV absorber or scattering agent flows out and the defense ability is reduced.

業界提出多種用以抑制紫外線防禦效果之光劣化之方法(專利文獻1)，又，開發出一種化妝料，關於其耐水性，具有即便與水分接觸，紫外線防禦效果亦不會降低，反而防禦效果會提昇之革新性能(專利文獻2)。The industry has proposed a variety of methods to suppress the photo-deterioration of the UV protection effect (Patent Document 1), and developed a cosmetic that has a water resistance that does not reduce the UV protection effect even in contact with moisture, but instead has a defense effect Improved innovative performance (Patent Document 2).

另一方面，與光或水分同樣地，亦無法忽視由熱所引起之紫外線防禦效果之降低。一般，若對塗抹於皮膚之化妝料施加熱，則化妝料中所包含之紫外線吸收劑或其他成分劣化，紫外線防禦效果會降低。然而，關於熱，雖存在例如研究熱對包含化妝料之乳化化妝料之乳化穩定性之影響之例(專利文獻3)，但至今為止未以由加熱所引起之紫外線防禦效果之變化作為研究對象。 [先前技術文獻] [專利文獻]On the other hand, like light or moisture, the reduction in the UV protection effect caused by heat cannot be ignored. Generally, if heat is applied to the cosmetic material applied to the skin, the ultraviolet absorber or other components contained in the cosmetic material will deteriorate, and the ultraviolet protection effect will be reduced. However, regarding heat, although there is an example of studying the effect of heat on the emulsification stability of emulsified cosmetics containing cosmetics (Patent Document 3), the change in the ultraviolet protection effect caused by heating has not been the subject of research so far. . [Prior Technical Literature] [Patent Literature]

[專利文獻1]日本專利特開2010-150172號公報 [專利文獻2]WO2016/068300號公報 [專利文獻3]日本專利第4397286號公報[Patent Document 1] Japanese Patent Laid-Open No. 2010-150172 [Patent Document 2] WO2016/068300 Publication [Patent Document 3] Japanese Patent No. 4397286

[發明所欲解決之問題][Problems to be solved by the invention]

據說一般到達至地表之紫外線量自4月起開始增加，於初夏(5月)至盛夏(8月)達到最大。於紫外線量達到最大之上述時間，藉由來自太陽之放射熱或來自地面之輻射熱等而皮膚被加熱。因此，較理想為若存在藉由施加熱而紫外線防禦能力提昇之防曬化妝料，則保護皮膚免遭較強之紫外線。因此，本發明之課題在於開發一種紫外線防禦能力藉由加熱而提昇之防曬化妝料、尤其是能夠提供此種防曬化妝料之添加劑。 [解決問題之技術手段]It is said that the amount of ultraviolet rays that generally reach the surface starts to increase in April, and reaches the maximum in early summer (May) to midsummer (August). At the above time when the amount of ultraviolet light reaches its maximum, the skin is heated by radiant heat from the sun or radiant heat from the ground. Therefore, it is desirable that if there is a sunscreen cosmetic that enhances the UV protection ability by applying heat, it protects the skin from strong UV rays. Therefore, the subject of the present invention is to develop a sunscreen cosmetic whose UV protection ability is enhanced by heating, and especially an additive capable of providing such sunscreen cosmetic. [Technical means to solve the problem]

本發明者等人為了解決上述問題而反覆進行努力研究，結果發現若於含有紫外線防禦劑之防曬化妝料中調配包含選自具有特定之IOB之兩親媒性物質或保濕劑中之至少1種的添加劑，則可獲得防曬化妝料之紫外線防禦效果藉由加熱而提昇(增強)之特別效果，從而完成本發明。In order to solve the above-mentioned problems, the inventors of the present invention have repeatedly studied hard, and found that if a sunscreen cosmetic containing a UV protection agent is formulated to contain at least one selected from an amphiphilic substance having a specific IOB or a moisturizer The additive of, can obtain the special effect of enhancing (enhancing) the UV protection effect of sunscreen cosmetics by heating, thus completing the present invention.

即，本發明提供一種用以藉由加熱而增強防曬化妝料之紫外線防禦效果之添加劑，其特徵在於包含選自IOB值為5.0以下之兩親媒性物質或保濕劑中之至少1種。 [發明之效果]That is, the present invention provides an additive for enhancing the UV protection effect of sunscreen cosmetics by heating, which is characterized by containing at least one selected from amphiphilic substances or moisturizers having an IOB value of 5.0 or less. [Effect of invention]

本發明之添加劑藉由將其調配於防曬化妝料中，比將該化妝料剛塗抹於皮膚後，可明顯提昇施加熱後之紫外線防禦能力。即，調配有本發明之添加劑之防曬化妝料成為紫外線防禦能力藉由先前視為劣化之原因之熱而提昇之新穎且革新的防曬化妝料。The additive of the present invention is formulated into sunscreen cosmetics, which can significantly improve the UV protection ability after applying heat compared to just after applying the cosmetics to the skin. That is, the sunscreen cosmetics formulated with the additives of the present invention become a novel and innovative sunscreen cosmetics whose UV protection ability is improved by the heat previously regarded as the cause of deterioration.

本發明係用以藉由加熱而增強防曬化妝料之紫外線防禦效果之添加劑，亦可稱為由防曬化妝料之加熱所帶來之紫外線防禦效果或防曬效果之增強劑。The present invention is an additive used to enhance the ultraviolet defense effect of sunscreen cosmetics by heating, and can also be referred to as an enhancer of ultraviolet defense effect or sunscreen effect brought by the heating of sunscreen cosmetics.

用以藉由加熱而增強本發明之防曬化妝料之紫外線防禦效果之添加劑(於本說明書中，亦簡稱為「添加劑」)之特徵在於包含選自IOB值為5.0以下之兩親媒性物質或保濕劑中之至少1種。The additives used to enhance the UV protection effect of the sunscreen cosmetics of the present invention by heating (also referred to as "additives" in this specification) are characterized by containing amphiphilic substances selected from an IOB value below 5.0 or At least one of the humectants.

「IOB」係「Inorganic/Organic Balance」之縮寫，定義IOB值=無機性值/有機性值。有機性值及無機性值係有機概念圖中分別對原子或官能基等賦予之特有之值。有機概念圖作為良好地表現相互作用相對複雜之有機物之性狀者，尤其廣泛用於環境化學領域、藥理化學領域等。關於詳細內容，例如可參照甲田善生著，「有機概念圖-基礎與應用-」，三共出版，1984年發行。"IOB" is the abbreviation of "Inorganic/Organic Balance", which defines IOB value = inorganic value/organic value. The organic value and the inorganic value are unique values assigned to atoms, functional groups, etc., respectively in the organic conceptual diagram. The organic concept map, as a good representation of the properties of relatively complex organic substances, is especially widely used in the fields of environmental chemistry and pharmacological chemistry. For details, please refer to Koda Yoshio, "Organic Concept Map-Basics and Applications -", published by Sankyo, published in 1984.

本發明之添加劑包含該IOB值為5.0以下、更佳為3.0以下、進而較佳為2.5以下之兩親媒性物質或保濕劑。若IOB值超過5.0，則有無法充分地獲得由熱所帶來之紫外線防禦能力提昇之效果之情形。IOB值之下限值並無特別限定(0以上、例如0.0001以上、0.001以上或0.01以上等)。The additive of the present invention includes an amphiphilic substance or humectant with an IOB value of 5.0 or less, more preferably 3.0 or less, and still more preferably 2.5 or less. If the IOB value exceeds 5.0, it may not be possible to fully obtain the effect of enhancing the UV protection ability caused by heat. The lower limit of the IOB value is not particularly limited (0 or more, for example, 0.0001 or more, 0.001 or more, or 0.01 or more).

本發明中之IOB值為5.0以下之兩親媒性物質或保濕劑較佳為分子內具有醚鍵者。其中，較佳為選自由下述式(I)： R₁ O-[(AO)_m (EO)_n ]-R₂ (I) (上述式(I)中，AO表示碳原子數3～4之氧伸烷基，EO表示氧伸乙基，R₁ 及R₂ 分別獨立地表示碳原子數1～4之烴基或氫原子，1≦m≦70，1≦n≦70)所表示之聚氧伸烷基·聚氧乙烯共聚物二烷基醚、以及選自下述式(II)： HO(RO)_p H (II) (式中，RO表示碳原子數2～4之氧伸烷基，p為3～500) 所表示之聚伸烷基二醇、及丁二醇、二丙二醇、雙甘油、丙二醇、赤藻糖醇、木糖醇、甲基葡萄糖10環氧乙烷、山梨糖醇中之多元醇所組成之群中。The amphiphilic substance or humectant having an IOB value of 5.0 or less in the present invention preferably has an ether bond in the molecule. Among them, it is preferably selected from the following formula (I): R ₁ O-[(AO) _m (EO) _n ]-R ₂ (I) (In the above formula (I), AO represents 3 to 4 carbon atoms The oxyalkylene group, EO represents the oxyethylene group, R ₁ and R ₂ each independently represent a hydrocarbon group with 1 to 4 carbon atoms or a hydrogen atom, 1≦m≦70, 1≦n≦70). Oxyalkylene·polyoxyethylene copolymer dialkyl ether, and selected from the following formula (II): HO(RO) _p H (II) (where, RO represents an oxyalkylene having 2 to 4 carbon atoms Group, p is 3～500) represented by polyalkylene glycol, butanediol, dipropylene glycol, diglycerol, propylene glycol, erythritol, xylitol, methyl glucose 10 ethylene oxide, sorbitol Among the group consisting of polyols in sugar alcohols.

上述式(I)所表示之聚氧伸烷基·聚氧乙烯共聚物二烷基醚(以下，簡稱為「POA-POE烷基醚」)中之AO表示碳原子數3～4之氧伸烷基。具體而言，可列舉：氧伸丙基、氧伸丁基、氧伸異丁基、氧三亞甲基、氧四亞甲基等。較佳為可列舉：氧伸丙基、氧伸丁基。EO表示氧伸乙基。In the polyoxyalkylene·polyoxyethylene copolymer dialkyl ether represented by the above formula (I) (hereinafter referred to as "POA-POE alkyl ether"), AO represents an oxygen extension with 3 to 4 carbon atoms alkyl. Specifically, oxypropylene, oxybutylene, oxyisobutyl, oxytrimethylene, oxytetramethylene, etc. can be mentioned. Preferably, oxypropylene and oxybutylene are mentioned. EO stands for oxyethylene.

式(I)中之m係1分子中之AO之平均加成莫耳數，1≦m≦70，較佳為1≦m≦30，進而較佳為1≦m≦20。n係1分子中之EO之平均加成莫耳數，1≦n≦70，較佳為1≦n≦30，進而較佳為1≦n≦20。於本發明中，使用m+n為40以下、較佳為25以下、進而較佳為20以下之POA-POE烷基醚。In formula (I), m is the average added molar number of AO in 1 molecule, 1≦m≦70, preferably 1≦m≦30, and more preferably 1≦m≦20. n is the average added molar number of EO in 1 molecule, 1≦n≦70, preferably 1≦n≦30, and more preferably 1≦n≦20. In the present invention, a POA-POE alkyl ether with m+n of 40 or less, preferably 25 or less, and more preferably 20 or less is used.

本發明中所使用之POA-POE烷基醚中之AO及EO之加成順序並無特別限定。可為AO與EO嵌段狀地加成之嵌段共聚物，或者亦可為無規加成之無規共聚物。嵌段共聚物不僅包括包含2段嵌段之共聚物，亦包括包含3段以上之嵌段之共聚物。較佳為使用無規共聚物。The order of addition of AO and EO in the POA-POE alkyl ether used in the present invention is not particularly limited. It can be a block copolymer in which AO and EO are added in block form, or it can be a random copolymer in which AO and EO are added randomly. Block copolymers include not only copolymers containing two-stage blocks, but also copolymers containing three or more blocks. It is preferable to use a random copolymer.

上述式(I)所表示之POA-POE烷基醚之分子量較佳為100～10000，更佳為200～5000，進而較佳為300～2000。又，一分子中之EO相對於AO與EO之合計之比率[EO/(AO+EO)]較佳為20～80質量%之範圍內。The molecular weight of the POA-POE alkyl ether represented by the above formula (I) is preferably 100 to 10,000, more preferably 200 to 5,000, and still more preferably 300 to 2,000. In addition, the ratio [EO/(AO+EO)] of EO in one molecule to the total of AO and EO is preferably in the range of 20 to 80% by mass.

式(I)中之R₁ 及R₂ 分別獨立地表示碳原子數1～4之烴基或氫原子。作為烴基，可列舉烷基、例如甲基、乙基、正丙基、異丙基、正丁基、第二丁基、第三丁基等。較佳為甲基、乙基。R ₁ and R ₂ in formula (I) each independently represent a hydrocarbon group having 1 to 4 carbon atoms or a hydrogen atom. As the hydrocarbon group, an alkyl group, for example, a methyl group, an ethyl group, an n-propyl group, an isopropyl group, an n-butyl group, a second butyl group, a tertiary butyl group, etc. can be mentioned. Preferred are methyl and ethyl.

POA-POE烷基醚1分子中之R₁ 及R₂ 可為相互相同之1種烴基，可混合存在烴基與氫原子，亦可混合存在碳原子數不同之複數個烴基。但是，關於R₁ 及R₂ 各者烴基與氫原子之存在比率，氫原子之數量(Y)相對於烴基之數量(X)之比率(Y/X)較佳為0.15以下，更佳為0.06以下。R ₁ and R _{2 in} one molecule of the POA-POE alkyl ether may be the same type of hydrocarbon group, a hydrocarbon group and a hydrogen atom may be mixed, or a plurality of hydrocarbon groups with different carbon atoms may be mixed. However, with regard to the ratio of the hydrocarbon groups and hydrogen atoms of each of R ₁ and R ₂ , the ratio (Y/X) of the number of hydrogen atoms (Y) to the number of hydrocarbon groups (X) is preferably 0.15 or less, more preferably 0.06 the following.

作為本發明中可良好地使用之POA-POE烷基醚之具體例，可列舉以下者，但並不限定於該等。 PEG/PPG-9/2二甲醚 PEG/PPG-17/4二甲醚 PEG/PPG-14/7二甲醚 PEG/PPG-11/9二甲醚 PEG/PPG-55/28二甲醚 PEG/PPG-36/41二甲醚 PEG/PPG-6/3二甲醚 PEG/PPG-8/4二甲醚 PEG/PPG-6/11二甲醚 PEG/PPG-14/27二甲醚As specific examples of POA-POE alkyl ethers that can be used satisfactorily in the present invention, the following can be cited, but they are not limited to these. PEG/PPG-9/2 dimethyl ether PEG/PPG-17/4 dimethyl ether PEG/PPG-14/7 dimethyl ether PEG/PPG-11/9 dimethyl ether PEG/PPG-55/28 dimethyl ether PEG/PPG-36/41 dimethyl ether PEG/PPG-6/3 dimethyl ether PEG/PPG-8/4 dimethyl ether PEG/PPG-6/11 dimethyl ether PEG/PPG-14/27 dimethyl ether

環氧烷衍生物有分子量相對越小，則由熱所帶來之紫外線防禦能力提昇效果越優異之傾向。因此，於以上所列舉之聚氧丙烯-聚氧乙烯共聚物二甲醚中，PEG/PPG-9/2二甲醚表現出最高之效果。The alkylene oxide derivatives have a tendency that the lower the molecular weight is, the better the effect of enhancing the UV protection ability caused by heat. Therefore, among the polyoxypropylene-polyoxyethylene copolymer dimethyl ethers listed above, PEG/PPG-9/2 dimethyl ether shows the highest effect.

另一方面，作為多元醇，可列舉：下述式(II)之聚伸烷基二醇、及丁二醇、二丙二醇、雙甘油、丙二醇、赤藻糖醇、木糖醇、甲基葡萄糖10環氧乙烷、山梨糖醇等。On the other hand, as polyhydric alcohols, polyalkylene glycols of the following formula (II), butylene glycol, dipropylene glycol, diglycerin, propylene glycol, erythritol, xylitol, and methyl glucose can be cited 10Ethylene oxide, sorbitol, etc.

此處，聚伸烷基二醇係下述式(II)： HO(RO)_p H (II) (式中，RO表示碳原子數2～4之氧伸烷基，p為3～500) 所表示者。具體而言，選自聚乙二醇(亦記載為「PEG」)、聚丙二醇(亦記載為「PPG」)及聚丁二醇(亦記載為「PBG」)等可用於化妝料等皮膚外用劑者。Here, the polyalkylene glycol is based on the following formula (II): HO(RO) _p H (II) (In the formula, RO represents an oxyalkylene group having 2 to 4 carbon atoms, and p is 3 to 500) Expressed. Specifically, selected from polyethylene glycol (also described as "PEG"), polypropylene glycol (also described as "PPG"), and polybutylene glycol (also described as "PBG"), etc. It can be used for external skin applications such as cosmetics Agent.

其中，較佳為於上述式(II)中RO為氧伸乙基，p為3～500、更佳為3～60之範圍之聚乙二醇。較佳之聚乙二醇之平均分子量為150～23000之範圍，進而較佳為150～3000之範圍。具體而言，可列舉：聚乙二醇300、聚乙二醇400、聚乙二醇1500、聚乙二醇20000等。Among them, it is preferable that RO is oxyethylene in the above formula (II), and p is 3 to 500, more preferably 3 to 60 polyethylene glycol. The average molecular weight of the preferred polyethylene glycol is in the range of 150-23,000, and more preferably in the range of 150-3,000. Specifically, polyethylene glycol 300, polyethylene glycol 400, polyethylene glycol 1500, polyethylene glycol 20000, and the like can be cited.

聚伸烷基二醇有分子量相對越小，則由熱所帶來之紫外線防禦能力提昇效果越優異之傾向。因此，於以上所列舉之聚乙二醇中，若使用聚乙二醇300或聚乙二醇400，則可獲得尤其高之效果。Polyalkylene glycol has a tendency that the lower the molecular weight is, the better the effect of enhancing the UV protection ability caused by heat. Therefore, among the polyethylene glycols listed above, if polyethylene glycol 300 or polyethylene glycol 400 is used, particularly high effects can be obtained.

本發明之添加劑可單獨包含1種IOB值為5.0以下之兩親媒性物質或保濕劑，亦可組合包含2種以上。例如較佳之例為包含至少1種式(I)之POA-POE烷基醚及至少1種式(II)之聚伸烷基二醇的添加劑。尤佳之例為PEG/PPG-9/2二甲醚與聚乙二醇300之組合。The additive of the present invention may contain one kind of amphiphilic substance or humectant with an IOB value of 5.0 or less, or two or more kinds in combination. For example, a preferred example is an additive containing at least one POA-POE alkyl ether of formula (I) and at least one polyalkylene glycol of formula (II). A particularly good example is the combination of PEG/PPG-9/2 dimethyl ether and polyethylene glycol 300.

本發明之添加劑可為僅包含IOB值為5.0以下之兩親媒性物質或保濕劑之態樣，亦可為包含其他成分之態樣。例如可列舉：使兩親媒性物質或保濕劑溶解於水或醇等水性介質中之態樣；使兩親媒性物質或保濕劑或其水溶液分散於油中之態樣等。The additive of the present invention may be a state that only contains an amphiphilic substance or a humectant with an IOB value of 5.0 or less, or a state that contains other ingredients. For example, a state in which the amphiphilic substance or moisturizer is dissolved in an aqueous medium such as water or alcohol; a state in which the amphiphilic substance or moisturizer or its aqueous solution is dispersed in oil.

本發明之添加劑並無特別限定，較佳為以相對於防曬化妝料總量，兩親媒性物質或保濕劑之量成為0.1質量%以上、例如0.1～25質量%、較佳為1.0～20質量%之量調配。若調配量未達0.1質量%，則有無法充分地獲得由熱所帶來之紫外線防禦能力提昇之效果之情形，若超過25質量%而調配，則有對防曬化妝料之穩定性或使用性造成影響之情形。The additive of the present invention is not particularly limited, but it is preferable that the amount of the amphiphilic substance or the humectant is 0.1% by mass or more, for example, 0.1-25% by mass, preferably 1.0-20, relative to the total amount of sunscreen cosmetics. The amount of mass% deployment. If the blending amount is less than 0.1% by mass, it may not be able to fully obtain the effect of enhancing the UV protection ability caused by heat. If it is blended with more than 25% by mass, it will have stability or usability for sunscreen cosmetics. The circumstances causing the impact.

構成本發明之添加劑之IOB值為5.0以下之兩親媒性物質或保濕劑、尤其是式(I)之POA-POE烷基醚及式(II)之聚伸烷基二醇係先前用於化妝料中之成分。因此，亦存在調配該等之防曬化妝料。例如於WO2017/057676中揭示藉由於包含4-第三丁基-4'-甲氧基二苯甲醯甲烷與甲氧基肉桂酸乙基己酯等特定之紫外線吸收劑之組合之防曬化妝料中調配相當於本發明之添加劑之兩親媒性物質或保濕劑，可抑制由光所引起之紫外線防禦效果之劣化。然而，於WO2017/057676中，利用將波長設定為300～800 nm之日照試驗機，對化妝料照射紫外線～可見光線，未照射賦予熱之紅外線。其結果為雖有效抑制先前之光劣化，但光照射後之紫外線防禦效果與照射前相比降低。即，未觀察到藉由加熱所帶來之紫外線防禦能力之提昇。Amphiphilic substances or humectants with an IOB value below 5.0 constituting the additives of the present invention, especially POA-POE alkyl ethers of formula (I) and polyalkylene glycols of formula (II) are previously used Ingredients in cosmetics. Therefore, there are also sunscreen cosmetics formulated with these. For example, WO2017/057676 discloses a sunscreen cosmetic made of a combination of specific ultraviolet absorbers such as 4-tert-butyl-4'-methoxydiphenylmethylmethane and ethylhexyl methoxycinnamate. The formulation of an amphiphilic substance or a humectant corresponding to the additive of the present invention can suppress the deterioration of the UV protection effect caused by light. However, in WO2017/057676, the cosmetics were irradiated with ultraviolet rays to visible rays using a solar radiation tester with a wavelength of 300 to 800 nm, and no heat-imparting infrared rays were irradiated. As a result, although the previous light degradation is effectively suppressed, the ultraviolet protection effect after light irradiation is lower than before irradiation. In other words, no improvement in the UV protection ability due to heating was observed.

構成本發明之添加劑之IOB值為5.0以下之兩親媒性物質或保濕劑雖與WO2017/057676中所記載之兩親媒性物質部分重複，但完全不一致。例如確認於WO2017/057676中，獲得光劣化之抑制效果之甘油(IOB=6.0)未表現出本發明之由熱所帶來之紫外線防禦能力提昇效果。Although the amphiphilic substance or humectant with an IOB value below 5.0 constituting the additive of the present invention partially overlaps with the amphiphilic substance described in WO2017/057676, it is completely inconsistent. For example, it is confirmed in WO2017/057676 that glycerin (IOB=6.0), which obtains the inhibitory effect of photo-deterioration, does not exhibit the effect of the present invention in enhancing the ultraviolet protection ability caused by heat.

本發明之添加劑藉由調配於防曬化妝料中，發揮其效果。調配本發明之添加劑之防曬化妝料並無特別限定，只要為至少含有紫外線吸收劑及/或紫外線散射劑等紫外線防禦劑之化妝料即可。The additive of the present invention exerts its effect by being formulated in sunscreen cosmetics. The sunscreen cosmetic to which the additive of the present invention is blended is not particularly limited, as long as it contains at least a ultraviolet ray protective agent such as an ultraviolet absorber and/or an ultraviolet scattering agent.

紫外線吸收劑並無特別限定，可廣泛列舉一般用於化妝料之紫外線吸收劑。例如可例示：苯甲酸衍生物、水楊酸衍生物、肉桂酸衍生物、二苯甲醯甲烷衍生物、β,β-二苯基丙烯酸酯衍生物、二苯甲酮衍生物、亞苄基樟腦衍生物、苯基苯并咪唑衍生物、三𠯤衍生物、苯基苯并***衍生物、鄰胺苯甲醯衍生物、咪唑啉衍生物、亞苄基丙二酸酯衍生物、4,4-二芳基丁二烯衍生物等。以下，列舉具體例及商品名等，但並不限定於該等。The ultraviolet absorber is not particularly limited, and a wide range of ultraviolet absorbers generally used in cosmetics can be cited. For example, benzoic acid derivatives, salicylic acid derivatives, cinnamic acid derivatives, dibenzyl methane derivatives, β, β-diphenyl acrylate derivatives, benzophenone derivatives, benzylidene Camphor derivatives, phenylbenzimidazole derivatives, tris derivatives, phenylbenzotriazole derivatives, o-aminobenzidine derivatives, imidazoline derivatives, benzylidene malonate derivatives, 4 , 4-Diarylbutadiene derivatives, etc. Hereinafter, specific examples, product names, etc. are given, but they are not limited to these.

作為苯甲酸衍生物，可例示：對胺基苯甲酸(PABA)乙酯、二羥基丙基PABA乙酯、二甲基PABA乙基己酯(例如「Escalol 507」；ISP公司)、PABA甘油酯、PEG-25-PABA(例如「Uvinul P25」；BASF公司)、二乙胺基羥基苯甲醯苯甲酸己酯(例如「Uvinul A Plus」；BASF公司)等。Examples of benzoic acid derivatives include: p-aminobenzoic acid (PABA) ethyl ester, dihydroxypropyl PABA ethyl ester, dimethyl PABA ethylhexyl ester (for example, "Escalol 507"; ISP company), PABA glyceride , PEG-25-PABA (such as "Uvinul P25"; BASF company), diethylamino hydroxybenzylhexyl benzoate (such as "Uvinul A Plus"; BASF company), etc.

作為水楊酸衍生物，可例示：胡莫柳酯(「Eusolex HMS」；Rona/EM Industries公司)、水楊酸乙基己酯(例如「NeoHeliopan OS」；Haarmann & Reimer公司)、二丙二醇水楊酸酯(例如「Dipsal」；Scher公司)、TEA水楊酸酯(例如「NeoHeliopan TS」；Haarmann & Reimer公司)等。Examples of salicylic acid derivatives include humosalate ("Eusolex HMS"; Rona/EM Industries), ethylhexyl salicylate (for example, "NeoHeliopan OS"; Haarmann & Reimer), dipropylene glycol water Salicylate (for example, "Dipsal"; Scher Company), TEA salicylate (for example, "NeoHeliopan TS"; Haarmann & Reimer Company), etc.

作為肉桂酸衍生物，可例示：甲氧基肉桂酸辛酯或甲氧基肉桂酸乙基己酯(例如「Parsol MCX」；Hoffmann-La Roche公司)、甲氧基肉桂酸異丙酯、甲氧基肉桂酸異戊酯(例如「NeoHeliopan E1000」；Haarmann & Reimer公司)、辛諾賽、DEA甲氧基肉桂酸酯、甲基肉桂酸二異丙酯、乙基己酸-二甲氧基肉桂酸甘油酯、4'-甲氧基亞苄基丙二酸二(2-乙基己基)酯等。Examples of cinnamic acid derivatives include octyl methoxycinnamate or ethylhexyl methoxycinnamate (for example, "Parsol MCX"; Hoffmann-La Roche company), isopropyl methoxycinnamate, and methoxycinnamate. Isoamyl cinnamate (for example "NeoHeliopan E1000"; Haarmann & Reimer), Sinoxa, DEA methoxycinnamate, diisopropyl methylcinnamate, ethylhexanoic acid-dimethoxycinnamon Acid glycerides, 4'-methoxybenzylidene malonate di(2-ethylhexyl) ester, etc.

作為二苯甲醯甲烷衍生物，可例示4-第三丁基-4'-甲氧基二苯甲醯甲烷(亦有時簡稱為「第三丁基甲氧基二苯甲醯甲烷」)(例如「Parsol 1789」；Hoffmann-La Roche公司)等。As the dityl methane derivative, 4-tertiary butyl-4'-methoxy dityl methane (also sometimes abbreviated as "tertiary butyl methoxy dityl methane") (for example, "Parsol 1789"; Hoffmann-La Roche Company) and so on.

作為β,β-二苯基丙烯酸酯衍生物，可例示奧克立林(例如「Uvinul N539T」；BASF公司)等。As β,β-diphenyl acrylate derivatives, octocrelin (for example, "Uvinul N539T"; BASF Corporation) and the like can be exemplified.

作為二苯甲酮衍生物，可例示：二苯甲酮-1(例如「Uvinul 400」；BASF公司)、二苯甲酮-2(例如「Uvinul D50」；BASF公司)、二苯甲酮-3或氧苯酮-3(例如「Uvinul M40」；BASF公司)、二苯甲酮-4(例如「Uvinul MS40」；BASF公司)、二苯甲酮-5、二苯甲酮-6(例如「Helisorb 11」；Norquay公司)、二苯甲酮-8(例如「Spectra-Sorb UV-24」；American Cyanamid公司)、二苯甲酮-9(例如「Uvinul DS-49」；BASF公司)、二苯甲酮-12等。Examples of benzophenone derivatives include benzophenone-1 (for example, "Uvinul 400"; BASF company), benzophenone-2 (for example, "Uvinul D50"; BASF company), and benzophenone- 3 or oxybenzone-3 (e.g. "Uvinul M40"; BASF company), benzophenone-4 (e.g. "Uvinul MS40"; BASF company), benzophenone-5, benzophenone-6 (e.g. "Helisorb 11"; Norquay company), benzophenone-8 (e.g. "Spectra-Sorb UV-24"; American Cyanamid company), benzophenone-9 (e.g. "Uvinul DS-49"; BASF company), Benzophenone-12 etc.

作為亞苄基樟腦衍生物，可例示：3-亞苄基樟腦(例如「Mexoryl SD」；Chimex公司)、4-甲基亞苄基樟腦、亞苄基樟腦磺酸(例如「Mexoryl SL」；Chimex公司)、甲基硫酸樟腦苄烷銨(例如「Mexoryl SO」；Chimex公司)、對苯二亞甲基二樟腦磺酸(例如「Mexoryl SX」；Chimex公司)、聚丙烯醯胺甲基亞苄基樟腦(例如「Mexoryl SW」；Chimex公司)等。Examples of benzylidene camphor derivatives include 3-benzylidene camphor (for example, "Mexoryl SD"; Chimex), 4-methylbenzylidene camphor, and benzylidene camphorsulfonic acid (for example, "Mexoryl SL"; Chimex company), camphor benzalkonium methyl sulfate (e.g. "Mexoryl SO"; Chimex company), p-xylylene dicamphorsulfonic acid (e.g. "Mexoryl SX"; Chimex company), polypropylene amide methyl Benzyl camphor (for example "Mexoryl SW"; Chimex Corporation) and the like.

作為苯基苯并咪唑衍生物，可例示：苯基苯并咪唑磺酸(例如「Eusolex 232」；Merck公司)、苯基二苯并咪唑四磺酸二鈉(例如「NeoHeliopan AP」；Haarmann & Reimer公司)等。Examples of phenylbenzimidazole derivatives include phenylbenzimidazole sulfonic acid (e.g. "Eusolex 232"; Merck), disodium phenyldibenzimidazole tetrasulfonate (e.g. "NeoHeliopan AP"; Haarmann & Reimer) and so on.

作為三𠯤衍生物，可例示：雙乙基己氧基苯酚甲氧基苯基三𠯤(例如「Tinosorb S」；Ciba Specialty Chemicals公司)、乙基己基三𠯤酮(例如「Uvinul T150」；BASF公司)、二乙基己基丁醯胺基三𠯤酮(例如「Uvasorb HEB」；3V Sigma公司)、2,4,6-三(4'-胺基亞苄基丙二酸二異丁酯)-s-三𠯤、2,4,6-三[4-(2-乙基己氧基羰基)苯胺基]-1,3,5-三𠯤等。Examples of tris derivatives include: bisethylhexyloxyphenol methoxyphenyl tris (for example "Tinosorb S"; Ciba Specialty Chemicals), ethylhexyl triketone (for example, "Uvinul T150"; BASF Company), diethylhexylbutyramidotriketone (such as "Uvasorb HEB"; 3V Sigma company), 2,4,6-tris(4'-aminobenzylidene diisobutylmalonate) -s-tris, 2,4,6-tris[4-(2-ethylhexyloxycarbonyl)anilino]-1,3,5-tris, etc.

作為苯基苯并***衍生物，可例示：甲酚曲唑三矽氧烷(例如「Silatrizole」；Rhodia Chimie公司)、亞甲基雙(苯并***基四甲基丁基苯酚)(例如「Tinosorb M」(Ciba Specialty Chemicals公司))等。Examples of phenyl benzotriazole derivatives include: Crestrozole trisiloxane (for example, "Silatrizole"; Rhodia Chimie), methylene bis (benzotriazole tetramethyl butyl phenol) ( For example, "Tinosorb M" (Ciba Specialty Chemicals)).

作為鄰胺苯甲醯衍生物，可例示鄰胺苯甲酸䓝酯(例如「NeoHeliopan MA」；Haarmann & Reimer公司)等。As an anthranilic derivative, anthranilate (for example, "NeoHeliopan MA"; Haarmann & Reimer) etc. can be exemplified.

作為咪唑啉衍生物，可例示二甲氧基亞苄基二氧代咪唑啉丙酸乙基己酯等。As the imidazoline derivative, ethylhexyl dimethoxybenzylidene dioxoimidazoline propionate etc. can be illustrated.

作為亞苄基丙二酸酯衍生物，可例示具有亞苄基丙二酸酯官能基之聚有機矽氧烷(例如聚矽氧烷-15；「Parsol SLX」；DSM Nutrition Japan公司)等。As the benzylidene malonate derivative, a polyorganosiloxane having a benzylidene malonate functional group (for example, polysiloxane-15; "Parsol SLX"; DSM Nutrition Japan) and the like can be exemplified.

作為4,4-二芳基丁二烯衍生物，可例示1,1-二羧基(2,2'-二甲基丙基)-4,4-二苯基丁二烯等。As the 4,4-diarylbutadiene derivative, 1,1-dicarboxy(2,2'-dimethylpropyl)-4,4-diphenylbutadiene and the like can be exemplified.

作為尤佳之例，並無限定，可列舉：甲氧基肉桂酸乙基己酯、奧克立林、聚二甲基矽氧烷二乙基亞苄基丙二酸酯、聚合矽-15、第三丁基甲氧基二苯甲醯甲烷、乙基己基三𠯤酮、二乙胺基羥基苯甲醯苯甲酸己酯、雙乙基己氧基苯酚甲氧基苯基三𠯤、氧苯酮-3、亞甲基雙(苯并***基四甲基丁基苯酚)、苯基苯并咪唑磺酸、3-(4'-甲基亞苄基)-d,l-樟腦、3-亞苄基-d,l-樟腦、胡莫柳酯、水楊酸乙基己酯等有機紫外線吸收劑。As a particularly preferred example, it is not limited, and examples include: ethylhexyl methoxycinnamate, octocrelin, polydimethylsiloxane diethylbenzylidene malonate, polysilicon-15 , Tertiary butyl methoxy dibenzyl methane, ethylhexyl tris ketone, diethylamino hydroxy benzoic hexyl benzoate, diethylhexyloxy phenol methoxy phenyl tris, oxybenzone -3, methylene bis (benzotriazole tetramethyl butyl phenol), phenyl benzimidazole sulfonic acid, 3-(4'-methylbenzylidene)-d,l-camphor, 3- Organic UV absorbers such as benzylidene-d,l-camphor, homosalate, and ethylhexyl salicylate.

紫外線散射劑並無特別限定，作為具體例，可列舉：微粒子狀之金屬氧化物、例如氧化鋅、氧化鈦、氧化鐵、氧化鈰、氧化鎢等。The ultraviolet scattering agent is not particularly limited. Specific examples include metal oxides in the form of fine particles, such as zinc oxide, titanium oxide, iron oxide, cerium oxide, and tungsten oxide.

紫外線散射劑可為未進行表面處理者，亦可為經各種疏水化表面處理者，較佳為使用經疏水化表面處理者。作為表面處理劑，可使用化妝料領域中通用者、例如聚二甲基矽氧烷、烷基改性聚矽氧等聚矽氧；辛基三乙氧基矽烷等烷氧基矽烷；糊精棕櫚酸酯等糊精脂肪酸酯；硬脂酸等脂肪酸。The ultraviolet scattering agent may be one that has not been surface-treated, or one that has been subjected to various hydrophobization surface treatments, and one that has been hydrophobized surface treatment is preferably used. As a surface treatment agent, those commonly used in the cosmetics field, such as polysiloxanes such as polydimethylsiloxane and alkyl-modified polysiloxane; alkoxysilanes such as octyltriethoxysilane; dextrin Dextrin fatty acid esters such as palmitate; fatty acids such as stearic acid.

紫外線防禦劑可為僅包含紫外線吸收劑之態樣、僅包含紫外線散射劑之態樣、以及包含紫外線吸收劑及紫外線散射劑兩者之態樣中之任一種。防曬化妝料中之紫外線防禦劑之調配量並無特別限定，通常相對於化妝料總量，為5質量%以上，例如為5～40質量%，較佳為6～40質量%，更佳為7～30質量%。若紫外線防禦劑之調配量未達5質量%，則難以獲得充分之紫外線防禦效果，即便超過40質量%地調配，亦無法期待與調配量對應之紫外線防禦效果之增加，穩定性變差，就該等方面而言不佳。The ultraviolet protection agent may be any one of the aspect including only the ultraviolet absorber, the aspect including only the ultraviolet scattering agent, and the aspect including both the ultraviolet absorber and the ultraviolet scattering agent. The blending amount of the ultraviolet protection agent in the sunscreen cosmetics is not particularly limited, and it is usually 5 mass% or more relative to the total amount of the cosmetics, for example, 5-40 mass%, preferably 6-40 mass%, more preferably 7-30% by mass. If the blending amount of the UV protection agent is less than 5% by mass, it is difficult to obtain a sufficient UV protection effect. Even if it is blended in excess of 40% by mass, the increase in the UV protection effect corresponding to the blending amount cannot be expected, and the stability will deteriorate. These aspects are not good.

再者，於調配第三丁基甲氧基二苯甲醯甲烷作為紫外線吸收劑之情形時，較佳為其調配量較少。例如較佳為相對於化妝料總量未達0.5質量%，或者相對於紫外線防禦劑總量設為10質量%以下。其原因在於第三丁基甲氧基二苯甲醯甲烷有阻礙調配本發明之添加劑時之由加熱所帶來之紫外線防禦效果之提昇的傾向，故而難以實際感受由熱所帶來之紫外線防禦效果之增強。Furthermore, in the case where tertiary butylmethoxydibenzoyl methane is formulated as the ultraviolet absorber, it is preferable that the compounding amount is smaller. For example, it is preferably less than 0.5% by mass relative to the total amount of cosmetics, or 10% by mass or less relative to the total amount of ultraviolet protection agent. The reason is that the tertiary butyl methoxydiphenylmethyl methacrylate has a tendency to hinder the improvement of the UV protection effect brought by heating when the additive of the present invention is formulated, so it is difficult to actually feel the UV protection effect brought by heat. Enhanced.

於防曬化妝料中，除紫外線防禦劑以外，亦可於不阻礙本發明之效果之範圍內調配通常用於化妝料之成分。例如可視需要適當調配pH值調整劑、螯合劑、防腐劑、抗氧化劑、油性活性劑、界面活性劑、水相增黏劑、醇類、粉末成分、著色劑、色素、藥劑等。作為藥劑，例如可例示：抗壞血酸(維生素C)、傳明酸、曲酸、土耳其鞣酸、熊果苷、烷氧基水楊酸、菸鹼醯胺、甘草酸、維生素E、視黃醇及該等之鹽或衍生物(例如L-抗壞血酸鈉、L-抗壞血酸酯鎂鹽、L-抗壞血酸葡萄糖苷、2-O-乙基-L-抗壞血酸、3-O-乙基-L-抗壞血酸、4-甲氧基水楊酸鈉鹽、4-甲氧基水楊酸鉀鹽、甘草酸二鉀、甘草酸硬脂酯、乙酸維生素E酯、乙酸視黃醇酯、棕櫚酸視黃醇酯等。又，亦可於不阻礙本發明之效果之範圍內調配甘油等IOB值超過5.0之保濕劑。In sunscreen cosmetics, in addition to ultraviolet protection agents, ingredients commonly used in cosmetics can also be blended within a range that does not hinder the effects of the present invention. For example, pH adjusters, chelating agents, preservatives, antioxidants, oily active agents, surfactants, water phase thickeners, alcohols, powder ingredients, coloring agents, pigments, medicaments, etc. can be appropriately formulated as needed. Examples of agents include ascorbic acid (vitamin C), tranexamic acid, kojic acid, turkey tannic acid, arbutin, alkoxy salicylic acid, nicotine amide, glycyrrhizic acid, vitamin E, retinol, and Such salts or derivatives (e.g., sodium L-ascorbate, magnesium L-ascorbate, L-ascorbyl glucoside, 2-O-ethyl-L-ascorbic acid, 3-O-ethyl-L-ascorbic acid, 4 -Methoxysalicylic acid sodium salt, 4-methoxysalicylic acid potassium salt, dipotassium glycyrrhizinate, stearyl glycyrrhizinate, vitamin E acetate, retinyl acetate, retinyl palmitate, etc. In addition, a humectant with an IOB value exceeding 5.0, such as glycerin, can also be formulated within a range that does not hinder the effects of the present invention.

防曬化妝料可為油性化妝料、油中水型乳化化妝料、水中油型乳化化妝料、多相乳化化妝料或水性化妝料之形態，並無特別限定。於為乳化化妝料之形態之情形時，藉由相對於化妝料總量調配5質量%以上之醇，可獲得乾爽之使用感或延展性之提昇。但是，若醇之調配量過多，則有乳化穩定性較差之情形，故而較佳為相對於化妝料量設為30質量%以下。又，於為乳化化妝料之情形時，較佳為於其油相調配IOB值為0.3以上之酯油。作為製品形態，不僅可以防曬化妝料之形式提供，亦可以賦予防曬效果之粉底等彩妝用化妝料或妝前乳、毛髮化妝料(包含用以保護毛髮或頭皮免遭紫外線之造型噴霧或護髮素等各種毛髮製品)、噴霧型化妝料等之形式提供。The sunscreen cosmetics can be in the form of oily cosmetics, water-in-oil emulsified cosmetics, oil-in-water emulsified cosmetics, multiphase emulsified cosmetics, or water-based cosmetics, and are not particularly limited. In the case of emulsified cosmetics, by blending 5% by mass or more of alcohol relative to the total amount of cosmetics, a dry feeling of use and an increase in ductility can be obtained. However, if the blending amount of the alcohol is too large, the emulsification stability may be inferior, so it is preferably 30% by mass or less relative to the amount of the cosmetic. Moreover, in the case of emulsified cosmetics, it is preferable to blend an ester oil with an IOB value of 0.3 or more in the oil phase. As a product form, it can be provided not only in the form of sunscreen cosmetics, but also make-up cosmetics such as foundations or primers that impart sunscreen effects, hair cosmetics (including styling sprays or hair care products to protect hair or scalp from ultraviolet rays) It is provided in the form of various hair products such as vegetarian), spray cosmetics, etc.

又，藉由於化妝料中調配球狀粉末，可抑制黏膩感，改善使用感而獲得乾爽之良好之觸感。作為球狀粉末，只要為一般用於化妝品等者，則可無特別限制而任意地使用。例如可列舉：(甲基)丙烯酸酯樹脂粉末、聚醯胺樹脂粉末(尼龍粉末)、聚乙烯粉末、聚苯乙烯粉末、苯乙烯與(甲基)丙烯酸之共聚物樹脂粉末、苯并胍胺樹脂粉末、聚四氟乙烯粉末、纖維素粉末及三甲基倍半矽氧烷粉末等、以及有機聚矽氧烷彈性體球狀粉末或以其作為母粉末之複合球狀粉末。球狀粉末之平均粒徑較佳為3～20 μm。若小於3 μm，則未見到抑制黏膩感之效果，若大於20 μm，則有反而產生粗澀感之情形。球狀粉末之調配量並無特別限定，較佳為1～30質量%，進而較佳為3～20質量%。In addition, by blending spherical powder in the cosmetics, stickiness can be suppressed, the feeling of use can be improved, and a dry and good touch can be obtained. As the spherical powder, as long as it is generally used for cosmetics, etc., it can be used arbitrarily without particular limitation. Examples include: (meth)acrylate resin powder, polyamide resin powder (nylon powder), polyethylene powder, polystyrene powder, copolymer resin powder of styrene and (meth)acrylic acid, benzoguanamine Resin powder, polytetrafluoroethylene powder, cellulose powder, trimethylsilsesquioxane powder, etc., as well as organopolysiloxane elastomer spherical powder or composite spherical powder using it as a mother powder. The average particle size of the spherical powder is preferably 3-20 μm. If it is less than 3 μm, the effect of suppressing stickiness is not seen, and if it is greater than 20 μm, a rough feeling may occur instead. The blending amount of the spherical powder is not particularly limited, but is preferably 1 to 30% by mass, and more preferably 3 to 20% by mass.

藉由本發明之添加劑所獲得之效果(紫外線防禦能力藉由加熱而提昇之效果)例如利用包括以下之步驟(i)至(iv)之評價方法進行確認。 (i)於基體上形成試樣組合物之塗膜； (ii)對試樣組合物之塗膜進行加熱處理； (iii)測定未進行加熱處理之試樣組合物之塗膜及進行過加熱處理之試樣組合物之塗膜的紫外線防禦效果；及 (iv)將測得之紫外線防禦效果進行比較。The effect obtained by the additive of the present invention (the effect of enhancing the ultraviolet protection ability by heating) is confirmed by, for example, an evaluation method including the following steps (i) to (iv). (i) Form a coating film of the sample composition on the substrate; (ii) Heat treatment of the coating film of the sample composition; (iii) Measure the UV protection effect of the coating film of the sample composition that has not been heated and the coating film of the sample composition that has been heated; and (iv) Compare the measured UV protection effects.

以下，一面參照圖1一面對於體外實施上述評價方法之情形進行說明。於步驟(i)中，將特定量之化妝料之樣品1塗抹於基體2，任意地進行乾燥，於基體2上形成樣品1之塗膜。可使用PMMA(polymethyl methacrylate，聚甲基丙烯酸甲酯)、尼龍、或丙烯酸系樹脂板等樹脂基板、玻璃或石英等無機物板作為基體。較佳為使用包含表面設置有V字形狀之槽之PMMA板之皮膚代替膜(亦稱為「S板」：參照日本專利第4453995號)等。繼而，測定所形成之樣品塗膜之加熱前之紫外線防禦效果(吸光度等)(步驟(i'))。Hereinafter, a case where the above-mentioned evaluation method is performed in vitro will be described with reference to FIG. 1. In step (i), a specific amount of sample 1 of cosmetics is applied to the base 2 and optionally dried to form a coating film of the sample 1 on the base 2. Resin substrates such as PMMA (polymethyl methacrylate), nylon, or acrylic resin plates, and inorganic plates such as glass or quartz can be used as the substrate. It is preferable to use a skin substitute film (also referred to as "S plate": refer to Japanese Patent No. 4453995) that includes a PMMA plate with a V-shaped groove on the surface. Then, the ultraviolet protection effect (absorbance, etc.) of the formed sample coating film before heating is measured (step (i')).

於下一步驟(ii)中，對步驟(i)中所形成之樣品塗膜賦予熱。步驟(ii)中之加熱溫度較佳為設為30℃～70℃之範圍。若加熱溫度超過70℃，則有產生樹脂製基板熔解等問題之情況。只要為上述範圍內之溫度，則並無特別限定，例如可設為32℃以上、35℃以上、37℃以上或40℃以上，亦可於65℃以下、60℃以下、55℃以下或50℃以下之溫度下進行加熱處理。為了確實地評價由熱所帶來之影響，加熱時間較佳為設為1分鐘以上，更佳為10分鐘以上。作為加熱時間之上限，並無特別限定，通常為60分鐘以下，較佳為30分鐘以下。In the next step (ii), heat is applied to the sample coating film formed in step (i). The heating temperature in step (ii) is preferably set in the range of 30°C to 70°C. If the heating temperature exceeds 70°C, problems such as melting of the resin substrate may occur. As long as the temperature is within the above range, it is not particularly limited. For example, it can be set to 32°C or higher, 35°C or higher, 37°C or higher, or 40°C or higher, or 65°C or lower, 60°C or lower, 55°C or lower or 50°C. Heat treatment at a temperature below ℃. In order to reliably evaluate the influence of heat, the heating time is preferably 1 minute or more, more preferably 10 minutes or more. The upper limit of the heating time is not particularly limited, but it is usually 60 minutes or less, preferably 30 minutes or less.

於步驟(ii)結束後，較佳為放置至基體之溫度恢復至常溫，測定各基體之樣品塗膜之特定波長(UVA或UVB區域)下之吸光度(步驟(iii))。After step (ii), it is preferable to place the substrate until the temperature of the substrate returns to normal temperature, and measure the absorbance of the sample coating film of each substrate at a specific wavelength (UVA or UVB region) (step (iii)).

最後，於步驟(iv)中，將加熱過之樣品塗膜之紫外線防禦效果與加熱前之樣品塗膜之紫外線防禦效果(步驟i')進行比較(未圖示)。Finally, in step (iv), compare the UV protection effect of the heated sample coating film with the UV protection effect of the sample coating film before heating (step i') (not shown).

紫外線防禦效果典型地於280～400 nm利用分光光度計等測定塗膜之吸光度，將樣品塗膜之吸光度累計值作為指標。即，於根據熱處理後之塗膜(加熱樣品)之吸光度累計值、及熱處理前之塗膜(非加熱樣品)之吸光度累計值，藉由以下之式：熱反應率(%)=(熱處理後之吸光度累計值)/(熱處理前之吸光度累計值)×100 所求出之熱反應率超過100%之情形時，定義為紫外線防禦效果藉由加熱而提昇。再者，亦可以單一波長(紫外線區域)下之吸光度、基於臨界波長或所測定之吸光度所算出之SPF或UVAPF(或PFA)作為指標，以代替上述吸光度累計值。The UV protection effect is typically measured at 280-400 nm using a spectrophotometer or the like to measure the absorbance of the coating film, and the cumulative value of the absorbance of the sample coating film is used as an index. That is, based on the cumulative value of the absorbance of the coating film (heated sample) after heat treatment and the cumulative value of the absorbance of the coating film (non-heated sample) before heat treatment, the following formula is used: Thermal response rate (%)=(cumulative absorbance value after heat treatment)/(cumulative absorbance value before heat treatment)×100 When the calculated thermal response rate exceeds 100%, it is defined as the increase in the UV protection effect by heating. Furthermore, the absorbance under a single wavelength (ultraviolet region), SPF or UVAPF (or PFA) calculated based on the critical wavelength or the measured absorbance can also be used as an index instead of the above-mentioned cumulative absorbance value.

於上述評價方法中，就排除熱以外之要因之影響之觀點而言，較佳為於遮斷紫外線之環境下實施加熱處理(步驟(ii))。 [實施例]In the above evaluation method, from the viewpoint of eliminating the influence of factors other than heat, it is preferable to perform the heat treatment in an environment where ultraviolet rays are blocked (step (ii)). [Example]

以下，列舉實施例進一步詳述本發明，但本發明不受該等任何限定。調配量只要未特別記載，則以相對於調配該成分之系統之質量%表示。Hereinafter, the present invention will be further described in detail with examples, but the present invention is not limited in any way. As long as there is no special description, the blending amount is expressed as a mass% relative to the system in which the component is blended.

製備下述表1～5之各例所示之配方之防曬化妝料(樣品)。將所獲得之樣品於常溫(25℃)下以2 mg/cm² 之塗抹量塗抹於PMMA製板後，使用吸光光度計測定280～400 nm之吸光度。將各例之樣品以2 mg/cm² 之量滴至近似皮膚PMMA板(SPFMASTER-PA01)，以手指塗抹60秒，乾燥15分鐘而形成塗膜。以未塗抹之板作為對照，利用日立製作所股份有限公司製造之U-3500型自動記錄分光光度計測定上述塗膜之吸光度(280～400 nm)，根據所獲得之測定資料求出熱處理前之吸光度累計值。The sunscreen cosmetics (samples) of the formulas shown in the following Tables 1 to 5 were prepared. The obtained sample was smeared on a PMMA plate at a smear amount of 2 mg/cm ² at room temperature (25°C), and then the absorbance at 280-400 nm was measured using an absorbance photometer. The samples of each example were dropped onto a skin-like PMMA board (SPFMASTER-PA01) at an amount of 2 mg/cm ² , applied with fingers for 60 seconds, and dried for 15 minutes to form a coating film. Using the unpainted plate as a control, the absorbance of the above-mentioned coating film (280-400 nm) was measured with the U-3500 automatic recording spectrophotometer manufactured by Hitachi, Ltd., and the absorbance before heat treatment was obtained based on the obtained measurement data Cumulative value.

繼而，將測定過之板於恆溫槽中於37℃下加熱30分鐘，恢復至室溫後，於與上述相同之條件下測定吸光度，根據所獲得之測定資料求出熱處理後之吸光度累計值。根據加熱前後之吸光度累計值，按照上述計算式，算出熱反應率。一併示出各例之熱反應率(%)之值。Then, the measured plate was heated in a constant temperature bath at 37°C for 30 minutes, and after returning to room temperature, the absorbance was measured under the same conditions as above, and the cumulative absorbance value after heat treatment was obtained from the obtained measurement data. According to the cumulative value of absorbance before and after heating, calculate the thermal reaction rate according to the above calculation formula. The thermal reaction rate (%) value of each example is also shown.

(1)油中水型乳化化妝料表1～3中所記載之各例之樣品係於使粉末分散於使用均質攪拌機所混合之油性成分中後，添加充分混合之水性成分而獲得油中水型乳化防曬化妝料。(1) Oil-in-water emulsified cosmetics The samples of each example described in Tables 1 to 3 were obtained by dispersing powder in oily ingredients mixed with a homomixer, and then adding sufficiently mixed aqueous ingredients to obtain water-in-oil emulsified sunscreen cosmetics.

[表1]

[Table 1]

[表2]

[Table 2]

[表3]

[table 3]

(2)水中油型乳化化妝料表4中所記載之例之樣品係於使粉末分散於使用均質攪拌機所混合之油性成分中後，於另外混合之水性成分中添加上述油性成分而獲得水中油型乳化防曬化妝料。(2) Oil-in-water emulsified cosmetics The samples of the examples described in Table 4 are obtained by dispersing the powder in the oily ingredients mixed with a homomixer, and then adding the oily ingredients to the separately mixed aqueous ingredients to obtain an oil-in-water emulsified sunscreen cosmetic.

[表4]

[Table 4]

(3)油性化妝料對下述表5所示之各例，使用均質攪拌機混合所有成分而獲得油性防曬化妝料。於包含油分固化劑之例中，於油性成分中添加油分固化劑進行加溫、熔解，添加保濕劑後，進行混合而使之均一化，其後進行冷卻而獲得油性固體防曬化妝料。(3) Oily cosmetics For each example shown in the following Table 5, all the ingredients were mixed using a homomixer to obtain an oil-based sunscreen cosmetic. In the example containing the oil-based curing agent, the oil-based curing agent is added to the oil-based component for heating and melting, and after adding the humectant, it is mixed to homogenize it, and then cooled to obtain an oil-based solid sunscreen cosmetic.

[表5]

[table 5]

如表1～5所示，確認藉由於各種形態之防曬化妝料中調配本發明之添加劑，發揮紫外線防禦效果藉由加熱而提昇之特有之效果。As shown in Tables 1 to 5, it was confirmed that by blending the additives of the present invention in various forms of sunscreen cosmetics, the unique effect of UV protection enhanced by heating is exerted.

以下，例示本發明之化妝料之配方。本發明當然不受該等配方例任何限定，而由申請專利範圍特定。再者，調配量均以相對於化妝料總量之質量%表示。Hereinafter, the formula of the cosmetic of the present invention is illustrated. Of course, the present invention is not limited in any way by these formulation examples, but is specified by the scope of patent application. In addition, the blending amount is expressed in mass% relative to the total amount of cosmetics.

配方例1：雙層式妝前乳 (成分名) 調配量(質量%) 純化水剩餘乙醇 5 PEG/PPG-9/2二甲醚 5 甘油 1 木糖醇 1 洋委陵菜萃取物 0.3 玻尿酸鈉 0.1 2-O-乙基-L-抗壞血酸 0.1 甘草酸二鉀 0.05 異十二烷 3 癸二酸二異丙酯 10 PBG/PPG-9/1共聚物 1 聚二甲基矽氧烷 13 聚甲基矽氧烷辛基聚甲基矽氧烷 3 高聚合胺基丙基聚二甲基矽氧烷20%之聚二甲基矽氧烷溶液 1 三氟烷基二甲基三甲基矽烷氧基矽酸50%聚二甲基矽氧烷溶液 3 糊精棕櫚酸酯 0.5 甲氧基肉桂酸乙基己酯 7 奧克立林 5 二乙胺基羥基苯甲醯苯甲酸己酯 1 雙乙基己氧基苯酚甲氧基苯基三𠯤 0.5 疏水化處理微粒子氧化鈦 2 疏水化處理微粒子氧化鋅 5 疏水化處理顏料級氧化鈦 1 疏水化處理氧化鐵 0.07 甲基丙烯酸甲酯交聯聚合物 2 (乙烯基聚二甲基矽氧烷/聚甲基矽氧烷倍半矽氧烷)交聯聚合物 2 疏水化處理滑石 2 PEG-9聚二甲基聚矽烷氧基乙基聚二甲基矽氧烷 1.5 PEG/PPG-19/19聚二甲基矽氧烷 0.3 二硬脂二甲銨鋰蒙脫石 0.4 異硬脂酸 0.3 EDTA·3Na 適量食鹽適量焦亞硫酸鈉適量維生素E 適量香料適量合計 100Formulation example 1: Double-layer makeup primer (Component name) Allocation amount (Quality %) Purified Water Remaining Ethanol 5 of the 5 PEG/PPG-9/2 Dimethyl ether 5 Glycerin ▒ ▒ ▫ ▫ ▫ ▫ 1 Xylitol Xylitol 1 Foreign vegetable extracts 0.3 Sodium hyaluronate 0.1 2-O-Ethyl-L-Ascorbic acid 0.1 Dipotassium Glycyrrhizinate 0.05 Isododecane 3 Diisopropyl Sebacate 10 PBG/PPG-9/1 copolymers 1 Poly-dimethylsiloxane 13 Polymethylsiloxane Octyl Polymethylsiloxane 3 Highly polymerized aminopropyl polydimethylsiloxane 20% polydimethylsiloxane solution 1 Trifluoroalkyl dimethyl trimethylsiloxy silicic acid 50% polydimethylsiloxane solution 3 Dextrin palmitate 0.5 Ethylhexyl methoxy cinnamic acid 7 Oklahoma City 5 of the Olympics Diethylamino hydroxybenzylhexyl benzoate hexyl benzoate 1 Diethylhexyloxy phenol methoxyphenyl tris 𠯤 0.5 Hydrophobicization of fine particles of titanium oxide 2 Hydrophobic treatment of fine particles of zinc oxide 5 Hydrophobic treatment of pigment-grade titanium oxide 1 Hydrophobizing iron oxide treatment 0.07 Methyl methacrylate cross-linked polymer 2 (Vinyl polydimethylsiloxane/polymethylsiloxane silsesquioxane) cross-linked polymer 2 Hydrophobic treatment of talc 2 PEG-9 polydimethylpolysiloxane oxyethyl polydimethylsiloxane 1.5 PEG/PPG-19/19 Polydimethylsiloxane 0.3 Two stearyl dimethylammonium lithium montmorillonite 0.4 Isostearic acid 0.3 EDTA 3Na Appropriate amount Table salt in a proper amount Sodium pyrosulfite in proper amount Vitamin E Appropriate amount Perfume in proper amount In total, 100 of the total

配方例2：乳霜狀之粉底 (成分名) 調配量(質量%) 純化水剩餘乙醇 5 苯氧基乙醇 1 PEG/PPG-9/2二甲醚 5 甘油 3 赤藻糖醇 1 木糖醇 1 洋委陵菜萃取物 1 甘胺醯甘胺酸 0.1 傳明酸 1 甘草酸二鉀 0.05 新戊酸三丙二醇 2 癸二酸二異丙酯 5 聚二甲基矽氧烷 10 環聚甲基矽氧烷 5 三矽烷氧基矽酸50%之環五矽氧烷溶液 2 糊精棕櫚酸酯 1 甲氧基肉桂酸乙基己酯 7 疏水化處理微粒子氧化鈦 3 疏水化處理微粒子氧化鋅 3 疏水化處理顏料級氧化鈦 6 疏水化處理氧化鐵 3.2 疏水化處理硫酸鋇被覆雲母鈦 0.01 疏水化處理雲母鈦 0.01 聚二甲基矽氧烷交聯聚合物13%之環五矽氧烷混合物 2 聚甲基倍半矽氧烷 2 甲基丙烯酸甲酯交聯聚合物 2 疏水化處理微粒子二氧化矽 0.5 月桂基PEG-9聚二甲基聚矽烷氧基乙基聚二甲基矽氧烷 2 (聚二甲基矽氧烷/(PEG-10/15))交聯聚合物 1 二硬脂二甲銨鋰蒙脫石 1 異硬脂酸 0.2 維生素E 適量 EDTA·3Na 適量食鹽適量焦亞硫酸鈉適量香料適量合計 100Formulation example 2: Creamy foundation (Component name) Allocation amount (Quality %) Purified Water Remaining Ethanol 5 of the 5 Phenoxyethanol ▫ 1 PEG/PPG-9/2 Dimethyl ether 5 Glycerin ▫ ▫ 3 Erythritol Alcohol 1 Xylitol Xylitol 1 Foreign vegetable extracts 1 Glyamine Glycine Glycine 0.1 It has been said that it is so acidic that it is 1 Dipotassium Glycyrrhizinate 0.05 Tripropylene glycol neopentanoic acid 2 2 Diisopropyl Sebacate 5 Polydimethylsiloxane 10 Cyclopolymethicone 5 Cyclopentasiloxane solution of 50% trisiloxysilicic acid 2 Dextrin palmitate dextrin palmitate Ethylhexyl methoxy cinnamic acid 7 Hydrophobic treatment of fine particles of titanium oxide 3 Hydrophobic treatment of fine particles of zinc oxide 3 Hydrophobic treatment of pigment-grade titanium oxide 6 Hydrophobic treatment of iron oxide 3.2 Hydrophobic treatment of barium sulfate covered mica titanium 0.01 Hydrophobic treatment of titanium mica Mica, 0.01 Polydimethylsiloxane cross-linked polymer 13% cyclopentasiloxane mixture 2 Polymethyl silsesquioxane 2 Methyl methacrylate cross-linked polymer 2 Hydrophobic treatment of fine particles of silicon dioxide 0.5 Lauryl PEG-9 polydimethylpolysiloxane oxyethyl polydimethylsiloxane 2 (Polydimethylsiloxane/(PEG-10/15)) cross-linked polymer 1 Dimethylammonium lithium montmorillonite bis-stearinite 1 Isostearic acid 0.2 Vitamin E Right amount EDTA 3Na Appropriate amount Table salt In amount of right amount Sodium pyrosulfite in a moderate amount of money. Fragrances Right amount In total, 100 of the total

配方例3：氣溶膠噴霧型之防曬劑 (成分名) 調配量(質量%) 純化水剩餘乙醇 5 聚乙二醇300 2 二氧化矽 0.5 甘油 1 PEG/PPG-14/7二甲醚 6 乙酸DL-α-維生素E酯 0.5 D-麩胺酸 0.1 甘草酸硬脂酯 0.1 異十二烷 10 三2-乙基己酸甘油酯 5 肉豆蔻酸異丙酯 3 癸二酸二異丙酯 5 PBG/PPG-9/1共聚物 1 聚二甲基矽氧烷 13 三矽烷氧基矽酸50%之環五矽氧烷溶液 0.5 三乙酸四硬脂酸蔗糖酯 0.5 糊精棕櫚酸酯 1 甲氧基肉桂酸乙基己酯 5 二乙胺基羥基苯甲醯苯甲酸己酯 2 雙乙基己氧基苯酚甲氧基苯基三𠯤 1 聚矽氧烷-15 2 奧克立林 5 甲基丙烯酸甲酯交聯聚合物 5 (乙烯基聚二甲基矽氧烷/聚甲基矽氧烷倍半矽氧烷)交聯聚合物 3 疏水化處理滑石 1 鯨蠟基PEG/PPG-10/1聚二甲基矽氧烷 1 月桂基PEG-9聚二甲基聚矽烷氧基乙基聚二甲基矽氧烷 1 二硬脂二甲銨鋰蒙脫石 0.5 異硬脂酸 0.3 山梨醇酐倍半異硬脂酸酯 0.3 EDTA·3Na 適量維生素E 適量香料適量合計 100 混合上述成分而製成原液，將原液與LPG以成為50：50之方式填充至噴霧罐中，獲得氣溶膠噴霧型之防曬劑。Formulation example 3: Aerosol spray type sunscreen (Component name) Allocation amount (Quality %) Purified Water Remaining Ethanol 5 of the 5 Polyethylene Glycol 300 2 Silicon dioxide 0.5 0.5 Glycerin ▒ ▒ ▫ ▫ ▫ ▫ ▫ ▫ 1 PEG/PPG-14/7 Dimethyl ether 6 Acetic acid DL-α-Vitamin E Ester 0.5 D-glutamic acid 0.1 Glycyrrhizinate stearyl glycyrrhizinate 0.1 Iso-dodecane, Iso-Dodecane, Iso-Dodecane, Iso-Dodecane, Iso-Dodecane, 10 Three 2-Ethylhexanoic Acid Glyceryl Ester 5-Ethylhexanoic Acid Glyceryl Ester 5 Isopropyl myristate 3 Diisopropyl Sebacate 5 PBG/PPG-9/1 copolymers 1 Poly-dimethylsiloxane 13 Cyclopentasiloxane solution of 50% trisiloxysilicic acid 0.5 Tetrastearic acid sucrose triacetic acid ester 0.5 Dextrin palmitate dextrin palmitate 1 Ethyl hexyl methoxycinnamate 5 Diethylamino hydroxybenzyl hexyl benzoate, hexyl benzoate, 2 Diethylhexyloxy phenol methoxyphenyl tris 𠯤 1 Polysilicone-15 2 Oklahoma City 5 of the Olympics Methyl methacrylate cross-linked polymer 5 (Vinyl polydimethylsiloxane/polymethylsiloxane silsesquioxane) cross-linked polymer 3 Hydrophobic treatment of talc 1 Cetyl PEG/PPG-10/1 Polydimethylsiloxane 1 Lauryl PEG-9 polydimethylpolysiloxane oxyethyl polydimethylsiloxane 1 Two stearyl dimethylammonium lithium montmorillonite 0.5 Isostearic acid 0.3 Sorbitol anhydride sesquiisostearic acid ester 0.3 EDTA 3Na Appropriate amount Vitamin E In right amount Fragrances Right amount In total, it is 100. The above-mentioned ingredients are mixed to prepare a stock solution, and the stock solution and LPG are filled in a spray can so that it becomes 50:50 to obtain an aerosol spray type sunscreen.

配方例4：凝膠狀之BB霜 (成分名) 調配量(質量%) 純化水剩餘乙醇 8 PEG/PPG-9/2二甲醚 5 刺蘼萃取物 0.1 硬脂醯氧基羥基丙基甲基纖維素 0.2 (二甲基丙烯醯胺/丙烯醯基二甲基牛磺酸鈉)共聚物 0.2 琥珀醯聚糖 0.1 甘油 3 聚乙二醇300 1 雙PEG-18甲醚二甲基矽烷 3 PEG/PPG-14/7二甲醚 1 甲氧基肉桂酸乙基己酯 10 癸二酸二異丙酯 5 二乙胺基羥基苯甲醯苯甲酸己酯 1 雙乙基己氧基苯酚甲氧基苯基三𠯤 3 疏水化處理微粒子氧化鈦 3 疏水化處理微粒子氧化鋅 5 疏水化處理顏料級鈦 4 疏水化處理氧化鐵 0.4 肉豆蔻酸異丙酯 2 聚丙二醇(17) 2 N-月桂醯基-L-麩胺酸二(膽固醇基·植物固醇基)酯 0.5 糊精(棕櫚酸/乙基己酸)酯 0.5 香料適量二氧化矽 1 合計 100Formulation example 4: BB cream in gel form (Component name) Allocation amount (Quality %) Purified Water Remaining Ethanol 8 of the 8 PEG/PPG-9/2 dimethyl ether 5 Glyph extract 0.1% Stearyloxy hydroxypropyl methyl cellulose 0.2 (Dimethacrylamide/Sodium Acrylate Dimethyl Taurate) Copolymer 0.2 Amber polyglycan 0.1 Glycerin s glycerin 3 Polyethylene Glycol 300,,,,,,,,,, 1 Double PEG-18 methyl ether dimethyl siloxane 3 PEG/PPG-14/7 Dimethyl ether 1 Ethylhexyl methoxycinnamic acid 10 Diisopropyl Sebacate 5 Diethylamino hydroxybenzylhexyl benzoate hexyl benzoate 1 Diethylhexyloxy phenol methoxyphenyl tris 𠯤 3 Hydrophobic treatment of fine particles of titanium oxide 3 Hydrophobic treatment of fine particles of zinc oxide 5 Hydrophobic treatment of pigment-grade titanium 4 Hydrophobic treatment of iron oxide 0.4........................ .. your.. your. Isopropyl myristate 2 Polypropylene Glycol(17) 2 N-Lauryl-L-glutamate bis (cholesteryl, phytosterol) ester 0.5 Dextrin (palmitic acid/ethylhexanoic acid) ester 0.5 Perfume in proper amount Silicon Dioxide One of the number 1 In total, 100 of the total

配方例5：乳液～乳霜狀之BB霜 (成分名) 調配量(質量%) 純化水剩餘乙醇 6 L-抗壞血酸磷酸酯鎂 0.5 乙醯化玻尿酸鈉 0.1 水溶性膠原蛋白 0.1 刺蘼萃取物 0.1 (二甲基丙烯醯胺/丙烯醯基二甲基牛磺酸鈉)共聚物 0.3 琥珀醯聚糖 0.2 纖維素膠 0.2 甘油 2 丁二醇 4 PEG/PPG-14/7二甲醚 3 PEG/PPG-9/2二甲醚 2 聚乙二醇300 1 聚氧乙烯氫化蓖麻油(100莫耳) 1 聚氧乙烯(8莫耳)山萮醚 1 硬脂醯基甲基牛磺酸鈉 0.1 硬脂醇 0.5 山萮醇 0.5 甲氧基肉桂酸乙基己酯 8 奧克立林 2 乙基己基三𠯤 1 二乙胺基羥基苯甲醯苯甲酸己酯 1 雙乙基己氧基苯酚甲氧基苯基三𠯤 1 異十二烷 10 癸二酸二異丙酯 5 聚二甲基矽氧烷 2 澳洲胡桃油脂肪酸植物固醇酯 1 N-月桂醯基-L-麩胺酸二(植物固醇基·辛基十二烷基)酯 0.5 糊精(棕櫚酸/乙基己酸)酯 0.5 疏水化處理微粒子氧化鋅 8 顏料級疏水化處理氧化鈦 4 疏水化處理氧化鐵 0.2 異硬脂酸 0.5 山梨醇酐倍半異硬脂酸酯 0.5 EDTA-2Na·H₂ O 適量六偏磷酸鈉適量檸檬酸適量檸檬酸鈉適量香料適量滑石 3 二氧化矽 3 合計 100Formulation example 5: Emulsion~Creamy BB cream (ingredient name) Blending amount (mass%) Remaining ethanol in purified water 6 Magnesium L-ascorbyl phosphate 0.5 Sodium acetylated hyaluronic acid 0.1 Water-soluble collagen 0.1 Spike extract 0.1 (Dimethacrylamide/Sodium Acrylonyl Dimethyl Taurate) Copolymer 0.3 Succinoglycan 0.2 Cellulose Gum 0.2 Glycerol 2 Butylene Glycol 4 PEG/PPG-14/7 Dimethyl Ether 3 PEG/ PPG-9/2 dimethyl ether 2 polyethylene glycol 300 1 polyoxyethylene hydrogenated castor oil (100 Mol) 1 Polyoxyethylene (8 mol) behenyl ether 1 Sodium stearyl methyl taurate 0.1 Stearyl alcohol 0.5 Behenyl alcohol 0.5 Ethylhexyl methoxycinnamate 8 Octrelin 2 Ethylhexyl tris 1 Diethylamino hydroxy benzoic acid hexyl benzoate 1 Diethylhexyloxy phenol methoxy phenyl tris 1 Isododecane 10 Diisopropyl sebacate 5 Polydimethyl Siloxane 2 Australian walnut oil fatty acid phytosterol ester 1 N-Lauryl-L-glutamic acid bis(phytosterol octyl dodecyl) ester 0.5 Dextrin (palmitic acid/ethylhexyl) Acid) Ester 0.5 Hydrophobized zinc oxide fine particles 8 Pigment grade hydrophobized titanium oxide 4 Hydrophobic treatment of iron oxide 0.2 Isostearic acid 0.5 Sorbitan sesquiisostearate 0.5 EDTA-2Na·H ₂ O Appropriate amount of sodium hexametaphosphate Appropriate amount of citric acid Appropriate amount of sodium citrate Appropriate amount of fragrance Appropriate amount of talc 3 Silicon dioxide 3 total 100

1:樣品 2:基體1: sample 2: matrix

圖1係表示本發明中可使用之評價方法之概略之說明圖。Fig. 1 is an explanatory diagram showing the outline of an evaluation method that can be used in the present invention.

Claims

一種用以藉由加熱而增強防曬化妝料之紫外線防禦效果之添加劑，其特徵在於包含選自由IOB值為5.0以下之兩親媒性物質或保濕劑所組成之群中之至少1種。An additive for enhancing the UV protection effect of sunscreen cosmetics by heating, which is characterized by containing at least one selected from the group consisting of amphiphilic substances or moisturizers with an IOB value of 5.0 or less.

如請求項1之添加劑，其中上述兩親媒性物質或保濕劑選自：下述式(I)： R₁ O-[(AO)_m (EO)_n ]-R₂ (I) (式(I)中，AO表示碳原子數3～4之氧伸烷基，EO表示氧伸乙基，R₁ 及R₂ 分別獨立地表示碳原子數1～4之烴基或氫原子，1≦m≦70，1≦n≦70) 所表示之聚氧伸烷基·聚氧乙烯共聚物二烷基醚；及選自由下述式(II)： HO(RO)_p H (II) (式中，RO表示碳原子數2～4之氧伸烷基，p為3～500) 所表示之聚伸烷基二醇、及丁二醇、二丙二醇、雙甘油、丙二醇、赤藻糖醇、木糖醇、甲基葡萄糖10環氧乙烷、山梨糖醇所組成之群中之多元醇。The additive of claim 1, wherein the above-mentioned amphiphilic substance or humectant is selected from the following formula (I): R ₁ O-[(AO) _m (EO) _n ]-R ₂ (I) (formula ( In I), AO represents an oxyalkylene group with 3 to 4 carbon atoms, EO represents an oxyalkylene group, R ₁ and R ₂ each independently represent a hydrocarbon group with 1 to 4 carbon atoms or a hydrogen atom, 1≦m≦ 70, 1≦n≦70) represented by polyoxyalkylene·polyoxyethylene copolymer dialkyl ether; and selected from the following formula (II): HO(RO) _p H (II) (where, RO represents an oxyalkylene group having 2 to 4 carbon atoms, and p is 3 to 500) represented by polyalkylene glycol, butanediol, dipropylene glycol, diglycerin, propylene glycol, erythritol, and xylose A polyol in the group consisting of alcohol, methyl glucose 10 ethylene oxide, and sorbitol.

如請求項2之添加劑，其包含至少1種上述式(I)所表示之聚氧伸烷基·聚氧乙烯共聚物二烷基醚、及至少1種上述式(II)所表示之聚伸烷基二醇。The additive of claim 2, which contains at least one polyoxyalkylene·polyoxyethylene copolymer dialkyl ether represented by the above formula (I), and At least one polyalkylene glycol represented by the above formula (II).

如請求項2或3之添加劑，其中上述式(I)所表示之聚氧伸烷基·聚氧乙烯共聚物二烷基醚為PEG/PPG-9/2二甲醚，上述式(II)所表示之聚伸烷基二醇為聚乙二醇300。The additive of claim 2 or 3, wherein the polyoxyalkylene·polyoxyethylene copolymer dialkyl ether represented by the above formula (I) is PEG/PPG-9/2 dimethyl ether, and the above formula (II) The polyalkylene glycol represented is polyethylene glycol 300.