TW202014215A - Power generating film and dressing including the same - Google Patents

Power generating film and dressing including the same Download PDF

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TW202014215A
TW202014215A TW108135702A TW108135702A TW202014215A TW 202014215 A TW202014215 A TW 202014215A TW 108135702 A TW108135702 A TW 108135702A TW 108135702 A TW108135702 A TW 108135702A TW 202014215 A TW202014215 A TW 202014215A
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water
membrane
soluble material
power generation
particles
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張源炘
沈芳如
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拓金造物股份有限公司
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303Constructional details

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Abstract

A conductive film includes a film body, an electrode material and a water soluble material. The electrode material and the water soluble material are disposed on the film body, and the water soluble material includes ionic compound.

Description

發電膜片及具有發電膜片的皮膚敷材Power generating membrane and skin dressing with power generating membrane

本發明係關於一種發電膜片,特別是一種含有水溶性材料的發電膜片以及包含此發電膜片的皮膚敷材。The invention relates to a power generation membrane, in particular to a power generation membrane containing a water-soluble material and a skin dressing containing the power generation membrane.

市面上的護膚產品將局部皮膚封閉起來,阻礙皮膚水分的蒸發,因而增加皮膚的含水量,提高皮膚水合化程度;同時由於皮膚溫度上升,有利於分子滲透,在一定程度上也促進活性成分的吸收。因此部分醫師認為敷材時就相當於皮膚科的封包治療,可增加皮膚對護膚品的吸收。另外,對於要將某些具有離子或帶電的化學物質,以經皮膚吸收的方式置入人體,還有離子導入法(Iontophoresis)可加以輔助。The skin care products on the market close the local skin and hinder the evaporation of skin moisture, thus increasing the moisture content of the skin and improving the degree of skin hydration; at the same time, because the skin temperature rises, it is conducive to molecular penetration and to a certain extent also promotes the active ingredients. absorb. Therefore, some doctors believe that the dressing is equivalent to the dermatology package treatment, which can increase the absorption of skin care products. In addition, for some chemical substances that have ions or charges to be inserted into the human body through skin absorption, there is also an iontophoresis method (Iontophoresis) to assist.

近年來,紙電池(印刷電池)技術發展迅速,由於其使用的材料污染性低而非常環保,而且簡便的生產過程有利於將低成本,配合其輕薄的外型更具有經濟競爭力。紙電池像鋰離子電池,又具有電容器的特性,能提供一個長期且穩定的功率輸出。因此,紙電池(印刷電池)的發展提供離子導入技術應用的另外一種途徑。In recent years, the technology of paper batteries (printed batteries) has developed rapidly, and the materials used are very environmentally friendly due to their low pollution, and the simple production process is conducive to low cost, and is more economically competitive with its thin and light appearance. Paper batteries, like lithium ion batteries, have the characteristics of capacitors and can provide a long-term and stable power output. Therefore, the development of paper batteries (printed batteries) provides another way of applying iontophoresis technology.

然而,當要應用紙電池以透過離子導入技術將護膚品送入皮膚內時,因為紙電池的輕薄特性,其所能積蓄的電能較為有限,導致水溶液中的護膚成分難以藉由電性排斥力被移動。However, when a paper battery is used to deliver skin care products into the skin through iontophoresis, the electrical energy that can be stored in the paper battery is relatively limited, which makes it difficult for skin care ingredients in aqueous solutions to be electrically repulsive. Be moved.

此外,一般而言,敷材在販售時都會浸泡在含有護膚品的水溶液中,造成敷材會因為擔心護膚品變質而設定具有較短的保存期限,進而不利於提高經濟競爭力。In addition, in general, the dressing is soaked in an aqueous solution containing skin care products when it is sold, causing the dressing to be set to have a shorter shelf life because of concerns about the deterioration of the skin care products, which is not conducive to improving economic competitiveness.

鑒於以上的問題,本發明揭露一種發電膜片以及包含此發電膜片的皮膚敷材,有助於解決護膚成分難以透過離子導入法進入皮膚深層以及產品保存期限短的問題。In view of the above problems, the present invention discloses a power generation membrane and a skin dressing containing the power generation membrane, which helps to solve the problems that skin care ingredients are difficult to penetrate into the deep layer of the skin through iontophoresis and the shelf life of the product is short.

本發明所揭露的發電膜片包含一膜片本體、一電極材料以及一水溶性材料。電極材料設置於膜片本體,且水溶性材料設置於膜片本體。水溶性材料包含離子化合物。The power generation membrane disclosed by the present invention includes a membrane body, an electrode material, and a water-soluble material. The electrode material is arranged on the diaphragm body, and the water-soluble material is arranged on the diaphragm body. The water-soluble material contains ionic compounds.

本發明所揭露的皮膚敷材包含前述的發電膜片。The skin dressing disclosed by the present invention includes the aforementioned power generation membrane.

根據本發明所揭露的發電膜片以及皮膚敷材,包含離子化合物的水溶性材料設置於膜片本體。當用液體浸濕發電膜片時,水溶性材料溶解而增加液體的導電性,有助於透過離子導入法將功能性材料水溶性材料連同功能性材料一起送入至皮膚深層。由於溶解的水溶性材料以及水溶性材料溶解後在膜片本體中形成的多孔通道能提升導電性,發電膜片不需要再額外包含用於提升導電性的物質。According to the power generation membrane and the skin dressing disclosed in the present invention, a water-soluble material containing an ionic compound is disposed on the membrane body. When the power generation membrane is wetted with liquid, the water-soluble material dissolves to increase the conductivity of the liquid, which helps to feed the functional material water-soluble material together with the functional material to the deep layer of the skin through iontophoresis. Since the dissolved water-soluble material and the porous channel formed in the membrane body after the water-soluble material is dissolved can improve conductivity, the power generation membrane does not need to additionally contain substances for improving conductivity.

此外,在做成產品販售時,本發明所揭露的皮膚敷材是將含有離子化合物的水溶性材料設置於膜片本體上,而非是用含有離子化合物的水溶液浸泡皮膚敷材,因此不用擔心會有水溶液變質的問題,而有助於延長皮膚敷材的保存期限。In addition, when the product is sold, the skin dressing disclosed in the present invention disposes a water-soluble material containing an ionic compound on the diaphragm body, instead of soaking the skin dressing with an aqueous solution containing an ionic compound, so it is not necessary Worried about the problem of deterioration of the aqueous solution, and help to extend the shelf life of skin dressings.

以上之關於本揭露內容之說明及以下之實施方式之說明係用以示範與解釋本發明之精神與原理,並且提供本發明之專利申請範圍更進一步之解釋。The above description of the disclosure and the following description of the embodiments are used to demonstrate and explain the spirit and principle of the present invention, and provide a further explanation of the scope of the patent application of the present invention.

以下在實施方式中詳細敘述本發明之詳細特徵以及優點,其內容足以使任何熟習相關技藝者瞭解本發明之技術內容並據以實施,且根據本說明書所揭露之內容、申請專利範圍及圖式,任何熟習相關技藝者可輕易地理解本發明相關之目的及優點。以下之實施例進一步詳細說明本發明之觀點,但非以任何觀點限制本發明之範疇。The following describes in detail the detailed features and advantages of the present invention in the embodiments. The content is sufficient for any person skilled in the relevant art to understand and implement the technical content of the present invention, and according to the contents disclosed in this specification, the scope of patent application and the drawings Anyone skilled in the relevant art can easily understand the purpose and advantages of the present invention. The following examples further illustrate the views of the present invention in detail, but do not limit the scope of the present invention in any way.

根據本發明的一實施例提供發電膜片,其包含膜片本體、電極材料以及水溶性材料。請參照圖1,為根據本發明第一實施例之發電膜片的示意圖。在本實施例中,發電膜片1a包含一膜片本體10a、一電極材料20a以及一水溶性材料30a。電極材料20a與水溶性材料30a皆設置於膜片本體10a。According to an embodiment of the present invention, a power generating membrane is provided, which includes a membrane body, an electrode material, and a water-soluble material. Please refer to FIG. 1, which is a schematic diagram of a power generating membrane according to a first embodiment of the present invention. In this embodiment, the power generation membrane 1a includes a membrane body 10a, an electrode material 20a, and a water-soluble material 30a. The electrode material 20a and the water-soluble material 30a are both disposed on the diaphragm body 10a.

電極材料20a包含多個電極材料粒子,並且電極材料粒子包含多個陽極粒子210a與多個陰極粒子220a。陽極粒子210a與陰極粒子220a散布於膜片本體10a內。The electrode material 20a includes a plurality of electrode material particles, and the electrode material particles include a plurality of anode particles 210a and a plurality of cathode particles 220a. The anode particles 210a and the cathode particles 220a are dispersed in the diaphragm body 10a.

水溶性材料30a包含多個水溶性材料粒子310a,且水溶性材料粒子310a散布於膜片本體10a內。The water-soluble material 30a includes a plurality of water-soluble material particles 310a, and the water-soluble material particles 310a are dispersed in the diaphragm body 10a.

圖2為根據本發明第二實施例之發電膜片的示意圖。在本實施例中,發電膜片1b包含膜片本體10a、一電極材料20b以及水溶性材料30a。電極材料20b與水溶性材料30a皆設置於膜片本體10a。電極材料20b包含多個陽極墊片210b與多個陰極墊片220b。陽極墊片210b與陰極墊片220b貼附於膜片本體10a其中一側的外表面。2 is a schematic diagram of a power generation membrane according to a second embodiment of the invention. In this embodiment, the power generation membrane 1b includes a membrane body 10a, an electrode material 20b, and a water-soluble material 30a. The electrode material 20b and the water-soluble material 30a are both disposed on the diaphragm body 10a. The electrode material 20b includes a plurality of anode gaskets 210b and a plurality of cathode gaskets 220b. The anode gasket 210b and the cathode gasket 220b are attached to the outer surface of one side of the diaphragm body 10a.

圖3為根據本發明第三實施例之發電膜片的示意圖。在本實施例中,發電膜片1c包含膜片本體10a、電極材料20a以及一水溶性材料30b。電極材料20a與水溶性材料30b皆設置於膜片本體10a。水溶性材料30b包含多個片狀或塊狀的水溶性材料單元310b,其貼附於膜片本體10a其中一側的外表面。3 is a schematic diagram of a power generation membrane according to a third embodiment of the present invention. In this embodiment, the power generation membrane 1c includes a membrane body 10a, an electrode material 20a, and a water-soluble material 30b. The electrode material 20a and the water-soluble material 30b are both disposed on the diaphragm body 10a. The water-soluble material 30b includes a plurality of sheet-shaped or block-shaped water-soluble material units 310b attached to the outer surface of one side of the diaphragm body 10a.

根據本發明的一實施例,膜片本體包含第一膜層與第二膜層。請參照圖4,為根據本發明第四實施例之發電膜片的示意圖。在本實施例中,發電膜片1d包含一膜片本體10b、電極材料20a以及水溶性材料30b。電極材料20a與水溶性材料30b皆設置於膜片本體10b。According to an embodiment of the invention, the diaphragm body includes a first film layer and a second film layer. Please refer to FIG. 4, which is a schematic diagram of a power generating membrane according to a fourth embodiment of the present invention. In this embodiment, the power generating membrane 1d includes a membrane body 10b, an electrode material 20a, and a water-soluble material 30b. The electrode material 20a and the water-soluble material 30b are both disposed on the diaphragm body 10b.

膜片本體10b包含一第一膜層110與一第二膜層120。The diaphragm body 10b includes a first film layer 110 and a second film layer 120.

電極材料20a包含多個陽極粒子210a與多個陰極粒子220a。部分陽極粒子210a與部分陰極粒子220a散布於第一膜層110內,且另一部分陽極粒子210a與另一部分陰極粒子220a散布於第二膜層120內。The electrode material 20a includes a plurality of anode particles 210a and a plurality of cathode particles 220a. Part of the anode particles 210a and part of the cathode particles 220a are dispersed in the first film layer 110, and the other part of the anode particles 210a and the other part of the cathode particles 220a are scattered in the second film layer 120.

水溶性材料30b包含多個片狀或塊狀的水溶性材料單元310b,其設置於第一膜層110與第二膜層120之間。更具體來說,第一膜層110與第二膜層120夾設水溶性材料單元310b。The water-soluble material 30b includes a plurality of sheet-shaped or block-shaped water-soluble material units 310b disposed between the first film layer 110 and the second film layer 120. More specifically, the first film layer 110 and the second film layer 120 sandwich the water-soluble material unit 310b.

圖5為根據本發明第五實施例之發電膜片的示意圖。在本實施例中,發電膜片1e包含膜片本體10c、電極材料20a以及水溶性材料30b。電極材料20a與水溶性材料30b皆設置於膜片本體10c。膜片本體10c除了第一膜層110與第二膜層120之外,還進一步包含一層間層130。層間層130設置於第一膜層110與第二膜層120之間,且水溶性材料30b的水溶性材料單元310b設置於層間層130內。5 is a schematic diagram of a power generation membrane according to a fifth embodiment of the invention. In this embodiment, the power generation membrane 1e includes a membrane body 10c, an electrode material 20a, and a water-soluble material 30b. The electrode material 20a and the water-soluble material 30b are both disposed on the diaphragm body 10c. In addition to the first film layer 110 and the second film layer 120, the diaphragm body 10c further includes an interlayer 130. The interlayer 130 is disposed between the first film layer 110 and the second film layer 120, and the water-soluble material unit 310 b of the water-soluble material 30 b is disposed in the interlayer 130.

圖6為根據本發明第六實施例之皮膚敷材的示意圖。在本實施例中,發電膜片1f包含膜片本體10c、電極材料20a以及水溶性材料30a。電極材料20a與水溶性材料30a皆設置於膜片本體10c。膜片本體10c除了第一膜層110與第二膜層120之外,還進一步包含設置於第一膜層110與第二膜層120之間的層間層130。水溶性材料30a的水溶性材料粒子310a散布於層間層130內。6 is a schematic diagram of a skin dressing according to a sixth embodiment of the present invention. In this embodiment, the power generation membrane 1f includes a membrane body 10c, an electrode material 20a, and a water-soluble material 30a. The electrode material 20a and the water-soluble material 30a are both disposed on the diaphragm body 10c. In addition to the first film layer 110 and the second film layer 120, the diaphragm body 10c further includes an interlayer 130 disposed between the first film layer 110 and the second film layer 120. The water-soluble material particles 310 a of the water-soluble material 30 a are dispersed in the interlayer 130.

在上述實施例中,膜片本體例如但不限於片狀水凝膠、不織布、疏水性黏結劑或丙稀酸類黏結劑。做為疏水性黏結劑的例子包括但不限於是矽樹脂、聚異丁烯及其衍生物、丙烯酸類、天然橡膠以及它們的組合。做為丙稀酸類黏結劑的例子包括但不限於是乙稀基(D醋酸酯-丙烯酸酯)共聚物。電極材料為純金屬或金屬合金,例如但不限於是鋅、鋁、銅、鎂、錳、銀、鈦、錫、鐵或上述金屬之合金。水溶性材料包含離子化合物,其例如但不限於是鹽酸鹽(舉例有氯化鈉、氯化鉀、氯化鋰、氯化鈣、氯化鍶、氯化鎂或其它鹽酸鹽)、鈉鹽、鉀鹽、鋰鹽、鈣鹽、鎂鹽、鍶鹽、氫氟酸鹽、氫碘酸鹽、氫溴酸鹽、磷酸鹽、檸檬酸鹽、醋酸鹽、乳酸鹽和硼酸鹽。在部分實施例中,水溶性材料可以含有二種以上可互相反應的組成。例如,水溶性材料30a可包含固態的碳酸鹽以及二氧化碳。此外,在膜片本體包含多個膜層的情況下,這些膜層可被堆疊或進一步透過黏合劑彼此結合。In the above embodiments, the membrane body is, for example but not limited to, sheet hydrogel, non-woven fabric, hydrophobic adhesive, or acrylic adhesive. Examples of hydrophobic binders include, but are not limited to, silicone resins, polyisobutylene and its derivatives, acrylics, natural rubber, and combinations thereof. Examples of acrylic adhesives include, but are not limited to, vinyl (D acetate-acrylate) copolymers. The electrode material is pure metal or metal alloy, such as but not limited to zinc, aluminum, copper, magnesium, manganese, silver, titanium, tin, iron or alloys of the above metals. Water-soluble materials include ionic compounds such as, but not limited to, hydrochloride salts (such as sodium chloride, potassium chloride, lithium chloride, calcium chloride, strontium chloride, magnesium chloride, or other hydrochloride salts), sodium salts, Potassium, lithium, calcium, magnesium, strontium, hydrofluoride, hydroiodide, hydrobromide, phosphate, citrate, acetate, lactate and borate salts. In some embodiments, the water-soluble material may contain two or more components that can react with each other. For example, the water-soluble material 30a may contain solid carbonate and carbon dioxide. In addition, in the case where the diaphragm body includes a plurality of film layers, these film layers may be stacked or further bonded to each other through an adhesive.

本發明所揭露的發電膜片可應用於皮膚敷材。請參照圖7和圖8,其中圖7為根據本發明第七實施例之皮膚敷材的示意圖,圖8為圖7之皮膚敷材貼附於人體皮膚的示意圖。在本實施例中,皮膚敷材2包含第一實施例所述的發電膜片1a,並且其中的水溶性材料30a進一步包含功能性材料320。功能性材料320包含具有美容效果或醫療效果的成分。本實施例以面膜作為皮膚敷材2的示例,但本發明並不以此為限。在其他實施例中,皮膚敷材可以是頸膜、手肘膜、腿膜或創傷用敷材。The power generation membrane disclosed by the invention can be applied to skin dressings. Please refer to FIGS. 7 and 8, wherein FIG. 7 is a schematic diagram of a skin dressing according to a seventh embodiment of the present invention, and FIG. 8 is a schematic diagram of the skin dressing of FIG. 7 attached to human skin. In this embodiment, the skin dressing 2 includes the power generation membrane 1a described in the first embodiment, and the water-soluble material 30a therein further includes a functional material 320. The functional material 320 contains ingredients having cosmetic effects or medical effects. This embodiment uses a facial mask as an example of the skin dressing 2, but the invention is not limited thereto. In other embodiments, the skin dressing may be a cervical membrane, elbow membrane, leg membrane, or wound dressing.

於使用皮膚敷材2時,將皮膚敷材2貼附於人體皮膚上,並且用液體(例如水)浸濕皮膚敷材2。當皮膚敷材2浸入液體時,水溶性材料粒子310a會溶解到液體3中,此時水溶性材料粒子310a中原本未離子化的離子化合物會因為碰到液體3而形成帶正電性離子與帶負電性離子。由於發電膜片1a與人體皮膚之間存在電位差,帶電性離子會受到陽極粒子210a與陰極粒子220a之間的電流驅動而向人體皮膚內部移動,從而達到透過離子導入法將水溶性材料粒子310a與功能性材料320有效輸送至皮膚深層。When the skin dressing 2 is used, the skin dressing 2 is attached to human skin, and the skin dressing 2 is wetted with liquid (for example, water). When the skin dressing 2 is immersed in liquid, the water-soluble material particles 310a will dissolve into the liquid 3. At this time, the ionic compounds in the water-soluble material particles 310a that were not ionized will form positively charged ions and Negatively charged ions. Due to the potential difference between the power generation membrane 1a and the human skin, the charged ions will be driven into the human skin by the current between the anode particles 210a and the cathode particles 220a, so that the water-soluble material particles 310a and The functional material 320 is effectively delivered to the deep layer of the skin.

此外,在水溶性材料粒子310a溶解到液體中後,膜片本體10a內部原本被水溶性材料粒子310a佔據的位置會形成多孔通道140,使得發電膜片1a與液體的接觸總面積變大,有助於增加導電性。In addition, after the water-soluble material particles 310a are dissolved in the liquid, a porous channel 140 is formed at the position originally occupied by the water-soluble material particles 310a in the diaphragm body 10a, so that the total area of contact between the power generation membrane 1a and the liquid becomes larger. Helps increase conductivity.

前述水溶性材料粒子中未離子化的離子化合物,可以是指呈乾燥態或凝膠態的離子化合物。例如,在圖1的實施例中,水溶性材料粒子可以是乾燥粉末;在圖3的實施例中,水溶性材料單元可以是由粉末聚集成的乾燥片狀體;在圖5的實施例中,水溶性材料單元可以是凝膠片。The non-ionized ionic compound in the aforementioned water-soluble material particles may refer to an ionic compound in a dry state or a gel state. For example, in the embodiment of FIG. 1, the water-soluble material particles may be dry powder; in the embodiment of FIG. 3, the water-soluble material unit may be a dry sheet body aggregated from the powder; in the embodiment of FIG. 5 The water-soluble material unit may be a gel sheet.

在本實施例中,所述功能性材料可以含有對人體皮膚具有美容效果的護膚品,或是含有對人體具有療效的藥物成分。舉例來說,功能性材料可包含諸如類胡蘿蔔素、抗壞血酸(維生素C)和維生素E以及其它維生素製劑之類的皮膚作用抗氧劑。在另一實施例中,水溶性材料還可進一步包含諸如維生素A(維生素A醇)、α羥基酸、β羥基酸(水楊酸)、組合羥基酸和多羥基酸之類的抗皺劑。又在另一實施例中,功能性材料還可進一步包含水解的和可溶解的膠原質及其他透明質酸等之類型的保濕液。又在另一實施例中,功能性材料還可包含諸如氨茶鹼及其他之類的抗脂肪團劑。又在另一實施例中,功能性材料還可進一步包含諸如視黃酸、對苯二酚和過氧化物及其他之類的皮膚漂白劑。又在另一實施例中,功能性材料還可進一步包含諸如真蘆薈、野生山藥、北美金縷梅鞣質、人參、綠茶及其他的提取物之類的植物製劑。又在另一實施例中,功能性材料例如包含肽、多肽、蛋白質、核苷酸包括DNA及滋養素等藥物成分。多肽和蛋白質活性劑的例子包括:促甲狀腺激素釋放激素(TRH)、加壓素、***釋放激素(GnRH or LHRH)、促黑激素(MSH)、降鈣素、生長激素釋放因子(GRF)、胰島素、紅細胞生成素(EPO)、干擾素α、干擾素β、催產素、卡托普利、緩激肽、心房肽、膽囊收縮素、內啡肽、神經生長因子、黑素細胞抑製劑-I、胃泌素拮抗劑、生長抑素(Somatotatin)、腦磷脂、褪黑激素、疫苗、A型肉毒毒素製劑(肉毒桿菌神經毒素)、環孢菌素及其衍生物(例如,生物活性片段或類似物)。其它活性劑包括:麻醉劑;鎮痛藥(例如,芬太尼及其鹽如枸櫞酸芬太尼);治療精神病、癲癇症和偏頭痛的藥物;停止藥物成癮和藥物濫用的藥物;抗炎藥;治療高血壓、心血管疾病、胃酸和潰瘍的藥物;用於激素替代療法和避孕的藥物如***和雄激素;抗生素、抗真菌藥、抗病毒藥及其它抗微生物劑;抗腫瘤藥、免疫抑製劑和免疫興奮劑;以及作用於血液和造血器官的藥物,包括造血藥和抗凝血藥、溶栓劑和抗血小板藥。可使用本發明剪切裝置傳遞入體內的其它活性劑包括多種疾病的疫苗,例如流行性感冒疫苗、AIDS疫苗、肝炎疫苗、麻疹疫苗、腮腺炎疫苗、風疹疫苗、狂犬病疫苗、風疹疫苗、avercella疫苗、破傷風疫苗、低丙球蛋白血症疫苗、Rh疾病疫苗、白喉疫苗、肉毒中毒疫苗、蛇咬疫苗、黑寡婦咬傷和其它昆蟲咬傷/螫傷的疫苗、特發性血小板減少性紫癜(ITP)疫苗、慢性淋巴細胞性白血病疫苗、巨細胞病毒(CMV)感染的疫苗、急性腎排斥反應的疫苗、口服脊髓灰質炎疫苗、結核病疫苗、百日咳疫苗、b型嗜血桿菌疫苗、肺炎球菌疫苗和金黃色葡萄球菌的疫苗。In this embodiment, the functional material may contain a skin care product having a cosmetic effect on human skin, or contain a pharmaceutical ingredient that has a therapeutic effect on the human body. For example, the functional material may include skin-acting antioxidants such as carotenoids, ascorbic acid (vitamin C) and vitamin E, and other vitamin preparations. In another embodiment, the water-soluble material may further include anti-wrinkle agents such as vitamin A (vitamin A alcohol), alpha hydroxy acid, beta hydroxy acid (salicylic acid), combined hydroxy acid and polyhydroxy acid. In yet another embodiment, the functional material may further include hydrolyzed and soluble collagen and other types of moisturizing fluids. In yet another embodiment, the functional material may also include anti-cellulite agents such as aminophylline and others. In yet another embodiment, the functional material may further include skin bleaching agents such as retinoic acid, hydroquinone and peroxide, and others. In yet another embodiment, the functional material may further include plant preparations such as true aloe vera, wild yam, witch hazel tannin, ginseng, green tea, and other extracts. In yet another embodiment, the functional materials include peptides, polypeptides, proteins, nucleotides including DNA, nutrients and other pharmaceutical ingredients. Examples of peptide and protein active agents include: Thyrotropin-releasing hormone (TRH), Vasopressin, Gonadotropin-releasing hormone (GnRH or LHRH), Melanotropin (MSH), Calcitonin, Growth hormone releasing factor (GRF) ), insulin, erythropoietin (EPO), interferon alpha, interferon beta, oxytocin, captopril, bradykinin, atrial peptide, cholecystokinin, endorphin, nerve growth factor, melanocyte suppression Formulation-I, gastrin antagonist, Somatotatin, cephalin, melatonin, vaccine, botulinum toxin type A preparation (botulinum neurotoxin), cyclosporine and its derivatives (e.g. , Biologically active fragments or the like). Other active agents include: anesthetics; analgesics (eg, fentanyl and its salts such as fentanyl citrate); drugs for the treatment of psychosis, epilepsy, and migraine; drugs to stop drug addiction and drug abuse; anti-inflammatory Medicines; medicines for treating hypertension, cardiovascular disease, stomach acid and ulcers; medicines for hormone replacement therapy and contraception such as estrogen and androgens; antibiotics, antifungal drugs, antiviral drugs and other antimicrobial agents; antitumor drugs, Immunosuppressive agents and immunostimulants; and drugs that act on blood and hematopoietic organs, including hematopoietic and anticoagulant drugs, thrombolytic agents and antiplatelet drugs. Other active agents that can be delivered into the body using the shear device of the present invention include vaccines for various diseases, such as influenza vaccine, AIDS vaccine, hepatitis vaccine, measles vaccine, mumps vaccine, rubella vaccine, rabies vaccine, rubella vaccine, avercella vaccine , Tetanus vaccine, hypogammaglobulinemia vaccine, Rh disease vaccine, diphtheria vaccine, botulism vaccine, snake bite vaccine, black widow bite and other insect bite/stab vaccines, idiopathic thrombocytopenic purpura (ITP) ) Vaccine, chronic lymphocytic leukemia vaccine, cytomegalovirus (CMV) infection vaccine, acute renal rejection vaccine, oral polio vaccine, tuberculosis vaccine, pertussis vaccine, haemophilus type b vaccine, pneumococcal vaccine and Vaccine for Staphylococcus aureus.

在一實施例中,功能性材料還可進一步包含超吸收聚合物。超吸收聚合物是指在0.5鎊/平方英寸的壓力下能夠吸收和保持至少約10倍於其重量的體液的材料。超吸收聚合物顆粒可為無機或有機交聯的親水性聚合物,例如聚乙烯醇、聚乙烯氧化物、交聯澱粉、瓜耳膠、黃原膠以及吸收製品製造領域中已知的其他材料。In an embodiment, the functional material may further include a superabsorbent polymer. Superabsorbent polymer refers to a material that can absorb and retain at least about 10 times its weight of body fluids under a pressure of 0.5 pounds per square inch. The superabsorbent polymer particles can be inorganic or organic cross-linked hydrophilic polymers, such as polyvinyl alcohol, polyethylene oxide, cross-linked starch, guar gum, xanthan gum, and other materials known in the art of manufacturing absorbent articles .

以下,提供本發明之具體實施例以及比較例,以進一步說明本發明之功效。The following provides specific examples and comparative examples of the present invention to further illustrate the effects of the present invention.

〔實施例〕[Examples]

提供一種面膜(即皮膚敷材),包含具有如圖1繪示之結構的發電膜片以及功能性材料。於發電膜片中,膜片本體為不織布,電極材料包含鋅粒子與銅粒子,且水溶性材料包含氯化鈉。功能性材料為維生素C。使用時,面膜以純水浸濕後貼附在人臉皮膚上。Provided is a facial mask (ie, skin dressing), which includes a power generation membrane having a structure as shown in FIG. 1 and a functional material. In the power generation membrane, the membrane body is a non-woven fabric, the electrode material includes zinc particles and copper particles, and the water-soluble material includes sodium chloride. The functional material is vitamin C. During use, the mask is soaked in pure water and attached to the skin of the face.

〔比較例〕[Comparative Example]

提供一種面膜,包含發電膜片以及功能性材料。發電膜片包含膜片本體以及電極材料,但未包含水溶性材料。膜片本體為不織布,電極材料包含鋅粒子與銅粒子,且功能性材料為維生素C。使用時,面膜以含有氯化鈉的水溶液浸濕後貼附在人臉皮膚上。Provided is a facial mask, which includes a power generation membrane and functional materials. The power generation membrane includes the membrane body and electrode materials, but does not include water-soluble materials. The membrane body is a non-woven fabric, the electrode material contains zinc particles and copper particles, and the functional material is vitamin C. During use, the mask is moistened with an aqueous solution containing sodium chloride and attached to the skin of the human face.

〔離子導入的效果〕[Effects of iontophoresis]

請參照圖9,為本發明實施例與比較例的離子導入效果的螢光影像圖。實施例與比較例中的功能性材料預先修飾了綠色螢光分子。以浸濕後的實施例與比較例之面膜分別貼附至人工皮膚,接著觀察維生素C進入人工皮膚深度的情況。從圖9來看,採用浸濕後的包含水溶性材料之面膜,可以在皮膚較深層的區域偵測到螢光(白色區域),這表示實施例的功能性材料能透過離子導入法進入至皮膚較深層的區域內。因為溶於水中的水溶性材料會聚集在電極材料附近,造成電極材料周圍的液體有很高的導電性,因此發電膜片能有效地將水溶性材料連同功能性材料一起送入皮膚內。此外,水溶性材料溶解後在膜片本體中形成的多孔通道能讓發電膜片與液體的接觸總面積變大,亦有助於增加導電性。Please refer to FIG. 9, which is a fluorescent image of the iontophoresis effect of the embodiment and the comparative example of the present invention. The functional materials in the examples and comparative examples are pre-modified with green fluorescent molecules. The wet masks of the examples and the comparative examples were attached to the artificial skin, and then the depth of vitamin C into the artificial skin was observed. From FIG. 9, using a wetted mask containing a water-soluble material, fluorescence (white area) can be detected in a deeper area of the skin, which means that the functional material of the embodiment can be entered by iontophoresis to In deeper areas of the skin. Because the water-soluble material dissolved in water will gather near the electrode material, resulting in a high conductivity of the liquid around the electrode material, the power generation membrane can effectively send the water-soluble material into the skin together with the functional material. In addition, the porous channels formed in the membrane body after the water-soluble material is dissolved can increase the total area of contact between the power generation membrane and the liquid, and also help to increase electrical conductivity.

綜上所述,本發明所揭露的發電膜片及皮膚敷材中,包含離子化合物的水溶性材料設置於膜片本體。當用液體浸濕發電膜片時,水溶性材料溶解而增加液體的導電性,有助於透過離子導入法將功能性材料水溶性材料連同功能性材料一起送入至皮膚深層。由於溶解的水溶性材料以及水溶性材料溶解後在膜片本體中形成的多孔通道能提升導電性,發電膜片不需要再額外包含用於提升導電性的物質。In summary, in the power generation membrane and skin dressing disclosed in the present invention, a water-soluble material containing an ionic compound is disposed on the membrane body. When the power generation membrane is wetted with liquid, the water-soluble material dissolves to increase the conductivity of the liquid, which helps to feed the functional material water-soluble material together with the functional material to the deep layer of the skin through iontophoresis. Since the dissolved water-soluble material and the porous channel formed in the membrane body after the water-soluble material is dissolved can improve conductivity, the power generation membrane does not need to additionally contain substances for improving conductivity.

此外,在做成產品販售時,本發明所揭露的皮膚敷材是將含有離子化合物的水溶性材料設置於膜片本體上,而非是用含有離子化合物的水溶液浸泡皮膚敷材,因此不用擔心會有水溶液變質的問題,而有助於延長皮膚敷材的保存期限。In addition, when the product is sold, the skin dressing disclosed in the present invention disposes a water-soluble material containing an ionic compound on the diaphragm body, instead of soaking the skin dressing with an aqueous solution containing an ionic compound, so it is not necessary Worried about the problem of deterioration of the aqueous solution, and help to extend the shelf life of skin dressings.

雖然本發明以前述之實施例揭露如上,然而這些實施例並非用以限定本發明。在不脫離本發明之精神和範圍內,所為之更動與潤飾,均屬本發明之專利保護範圍。關於本發明所界定之保護範圍請參考所附之申請專利範圍。Although the present invention is disclosed as the foregoing embodiments, these embodiments are not intended to limit the present invention. Without departing from the spirit and scope of the present invention, all modifications and retouching are within the scope of patent protection of the present invention. For the protection scope defined by the present invention, please refer to the attached patent application scope.

1a、1b、1c、1d、1e、1f:發電膜片 2:皮膚敷材 3:液體 10a、10b、10c:膜片本體 110:第一膜層 120:第二膜層 130:層間層 140:多孔通道 20a、20b:電極材料 210a:陽極粒子 220a:陰極粒子 210b:陽極墊片 220b:陰極墊片 30a、30b:水溶性材料 310a:水溶性材料粒子 310b:水溶性材料單元 320:功能性材料 1a, 1b, 1c, 1d, 1e, 1f: power generation diaphragm 2: skin dressing 3: liquid 10a, 10b, 10c: diaphragm body 110: first film 120: second film 130: Interlayer 140: porous channel 20a, 20b: electrode material 210a: anode particles 220a: Cathode particles 210b: anode gasket 220b: cathode gasket 30a, 30b: water-soluble materials 310a: water-soluble material particles 310b: Water-soluble material unit 320: Functional materials

圖1為根據本發明第一實施例之發電膜片的示意圖。 圖2為根據本發明第二實施例之發電膜片的示意圖。 圖3為根據本發明第三實施例之發電膜片的示意圖。 圖4為根據本發明第四實施例之發電膜片的示意圖。 圖5為根據本發明第五實施例之發電膜片的示意圖。 圖6為根據本發明第六實施例之發電膜片的示意圖。 圖7為根據本發明第七實施例之皮膚敷材的示意圖。 圖8為圖7之皮膚敷材貼附於人體皮膚的示意圖。 圖9為本發明實施例與比較例的離子導入效果的螢光影像圖。FIG. 1 is a schematic diagram of a power generation membrane according to a first embodiment of the invention. 2 is a schematic diagram of a power generation membrane according to a second embodiment of the invention. 3 is a schematic diagram of a power generation membrane according to a third embodiment of the present invention. 4 is a schematic diagram of a power generation membrane according to a fourth embodiment of the invention. 5 is a schematic diagram of a power generation membrane according to a fifth embodiment of the invention. 6 is a schematic diagram of a power generation membrane according to a sixth embodiment of the invention. 7 is a schematic diagram of a skin dressing according to a seventh embodiment of the present invention. 8 is a schematic diagram of the skin dressing of FIG. 7 attached to human skin. 9 is a fluorescent image diagram of the iontophoresis effect of Examples and Comparative Examples of the present invention.

1a:發電膜片 1a: Power generation diaphragm

10a:膜片本體 10a: diaphragm body

20a:電極材料 20a: electrode material

210a:陽極粒子 210a: anode particles

220a:陰極粒子 220a: Cathode particles

30a:水溶性材料 30a: water-soluble material

310a:水溶性材料粒子 310a: water-soluble material particles

Claims (10)

一種發電膜片,包含:一膜片本體;一電極材料,設置於該膜片本體;以及一水溶性材料,設置於該膜片本體,且該水溶性材料包含離子化合物。A power generation diaphragm includes: a diaphragm body; an electrode material disposed on the diaphragm body; and a water-soluble material disposed on the diaphragm body, and the water-soluble material includes an ionic compound. 如申請專利範圍第1項所述的發電膜片,其中該電極材料包含多個電極材料粒子,且該些電極材料粒子散布於該膜片本體內。The power generation membrane as described in item 1 of the patent application range, wherein the electrode material includes a plurality of electrode material particles, and the electrode material particles are dispersed in the membrane body. 如申請專利範圍第2項所述的發電膜片,其中該些電極材料粒子包含多個陽極粒子與多個陰極粒子。The power generation membrane as described in item 2 of the patent application range, wherein the electrode material particles include a plurality of anode particles and a plurality of cathode particles. 如申請專利範圍第1項所述的發電膜片,其中該水溶性材料包含多個水溶性材料粒子,且該些水溶性材料粒子散布於該膜片本體內。The power generation membrane according to item 1 of the patent application scope, wherein the water-soluble material includes a plurality of water-soluble material particles, and the water-soluble material particles are dispersed in the body of the membrane. 如申請專利範圍第1項所述的發電膜片,其中該膜片本體包含一第一膜層與一第二膜層,該電極材料設置於該第一膜層與該第二膜層,且該水溶性材料設置於該第一膜層與該第二膜層之間。The power generation membrane according to item 1 of the patent application scope, wherein the membrane body includes a first membrane layer and a second membrane layer, the electrode material is disposed on the first membrane layer and the second membrane layer, and The water-soluble material is disposed between the first film layer and the second film layer. 如申請專利範圍第5項所述的發電膜片,其中該活性材料包含多個電極材料粒子,且該些電極材料粒子散布於該第一膜層與該第二膜層內。The power generation membrane of claim 5 in the patent application scope, wherein the active material includes a plurality of electrode material particles, and the electrode material particles are dispersed in the first film layer and the second film layer. 如申請專利範圍第5項所述的發電膜片,其中該膜片本體更包含一層間層,該層間層設置於該第一膜層與該第二膜層之間,且該水溶性材料設置於該層間層內。The power generation membrane according to item 5 of the patent application scope, wherein the membrane body further includes an interlayer, the interlayer is disposed between the first membrane layer and the second membrane layer, and the water-soluble material is disposed In this interlayer. 如申請專利範圍第1項所述的發電膜片,其中該水溶性材料包含未離子化的離子化合物。The power generation membrane as described in item 1 of the patent application range, wherein the water-soluble material contains an unionized ionic compound. 一種皮膚敷材,包含如申請專利範圍第1項至第8項任一項所述的發電膜片。A skin dressing comprising the power generating membrane according to any one of the patent application items 1 to 8. 如申請專利範圍第9項所述的皮膚敷材,其中該水溶性材料更包含具有美容效果或醫療效果的成分。The skin dressing as described in item 9 of the patent application range, wherein the water-soluble material further contains ingredients having cosmetic or medical effects.
TW108135702A 2018-10-03 2019-10-02 Power generating film and dressing including the same TW202014215A (en)

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