TW201605699A - Medicine dispensing system and medicine dispensing method - Google Patents

Medicine dispensing system and medicine dispensing method Download PDF

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TW201605699A
TW201605699A TW103141827A TW103141827A TW201605699A TW 201605699 A TW201605699 A TW 201605699A TW 103141827 A TW103141827 A TW 103141827A TW 103141827 A TW103141827 A TW 103141827A TW 201605699 A TW201605699 A TW 201605699A
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powder
dispensing
tray
medicine
drug
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TW103141827A
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Chinese (zh)
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TWI633041B (en
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Hiroyuki Yuyama
Chisei Asaoka
Tomonari Oda
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Yuyama Mfg Co Ltd
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B37/00Supplying or feeding fluent-solid, plastic, or liquid material, or loose masses of small articles, to be packaged
    • B65B37/16Separating measured quantities from supply
    • B65B37/18Separating measured quantities from supply by weighing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/002Compounding apparatus specially for enteral or parenteral nutritive solutions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B37/00Supplying or feeding fluent-solid, plastic, or liquid material, or loose masses of small articles, to be packaged
    • B65B37/04Supplying or feeding fluent-solid, plastic, or liquid material, or loose masses of small articles, to be packaged by vibratory feeders
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B9/00Enclosing successive articles, or quantities of material, e.g. liquids or semiliquids, in flat, folded, or tubular webs of flexible sheet material; Subdividing filled flexible tubes to form packages
    • B65B9/02Enclosing successive articles, or quantities of material between opposed webs
    • B65B9/04Enclosing successive articles, or quantities of material between opposed webs one or both webs being formed with pockets for the reception of the articles, or of the quantities of material
    • B65B9/042Enclosing successive articles, or quantities of material between opposed webs one or both webs being formed with pockets for the reception of the articles, or of the quantities of material for fluent material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/02Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of powders

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Basic Packing Technique (AREA)
  • Supply Of Fluid Materials To The Packaging Location (AREA)

Abstract

Provided is a medicine dispensing system that is capable of putting a precise amount of medicine in a package for one dose even when the amount of one dose (one package) and the number of individual doses are small. This medicine dispensing system has a medicine feeder (5) for discharging a powdered medicine, a dispensing tray (201), a scraping-out device (600), and a medicine packaging device (410). In a distributed arrangement mode, when dropping the medicine onto the dispensing tray (201) from a medicine container (2), only one dose of medicine is dropped into a medicine loading groove (208) of the dispensing tray (201) without rotating the dispensing tray (201). Once the one dose of medicine is dropped, the discharging of the medicine is interrupted, and the dispensing tray (201) is slightly rotated. This process is repeated to form a powdered medicine group comprising three mounds (22, 23, 24) on the groove surfaces of the dispensing tray (201). Subsequently, a scraping-out mechanism (606) is moved into the medicine loading groove (208) of the dispensing tray (201) in order to scrape out the medicine.

Description

分藥裝置及分藥方法 Drug dispensing device and drug dispensing method

本發明係關於一種分藥裝置,尤其係關於一種具備分配散劑之分配盤之分藥裝置。又,本發明係關於一種分裝藥劑之方法。 The present invention relates to a dispensing device, and more particularly to a dispensing device having a dispensing tray for dispensing a powder. Further, the present invention relates to a method of dispensing a medicament.

近年來,於大醫院或大規模之藥店,應用有散劑分包裝置或具備散劑分包功能之分藥裝置。此處所謂散劑分包裝置係指基於處方資訊而按一次服用量逐次個別地包裝散劑之裝置。若使用散劑分包裝置,則可使按一次服用量逐次地包裝散劑之作業之大部分自動化。 In recent years, in large hospitals or large-scale pharmacies, powder dispensing devices or dispensing devices with powder dispensing functions have been applied. The term "dispensing device" as used herein refers to a device for individually packaging a powder in a single dose based on prescription information. If a powder dispensing device is used, most of the operation of packaging the powder in a single dose can be automated.

專利文獻1中揭示之散劑分包裝置900係按一次服用量逐次個別地包裝散劑之裝置,如圖14所示,於其內部具有給粉器901、散劑分配裝置902、及藥劑包裝裝置903。 The powder dispensing device 900 disclosed in Patent Document 1 is a device for individually packaging a powder in a single dose, and as shown in FIG. 14, has a powder feeder 901, a powder dispensing device 902, and a drug packaging device 903 therein.

給粉器901具有料斗905及槽910。於槽910下設置有未圖示之壓電元件,而可使槽910振動。 The powder feeder 901 has a hopper 905 and a tank 910. A piezoelectric element (not shown) is provided under the groove 910, and the groove 910 can be vibrated.

如圖14所示,散劑分配裝置902包含分配盤912、及刮出裝置915。分配盤912於中央具有較大之開口。又,於分配盤912之上述開口之周圍環繞有剖面為圓弧狀、且俯視為環狀之槽916。分配盤912可藉由馬達919而旋轉。分配盤912能以固定之旋轉速度連續地旋轉,亦可限定為固定之旋轉角度而轉動。 As shown in FIG. 14, the powder dispensing device 902 includes a dispensing tray 912 and a scraping device 915. The distribution plate 912 has a larger opening in the center. Further, a groove 916 having an arcuate cross section and an annular shape in a plan view is formed around the opening of the distribution plate 912. The distribution plate 912 can be rotated by the motor 919. The distribution plate 912 can be continuously rotated at a fixed rotational speed, or can be limited to rotate at a fixed rotational angle.

刮出裝置915包含藉由轉動而前端升降之升降臂、及刮出機構。 The scraping device 915 includes a lifting arm that moves up and down by rotation, and a scraping mechanism.

刮出機構915具有藉由馬達而旋轉之碟狀之刮集板917,且於該刮集板917設置有刮出板918。 The scraping mechanism 915 has a dish-shaped scraping plate 917 that is rotated by a motor, and a scraping plate 918 is provided on the scraping plate 917.

如圖14所示,藥劑包裝裝置903包含包裝用料斗920、及包裝裝置921。 As shown in FIG. 14, the medicine packaging device 903 includes a packaging hopper 920 and a packaging device 921.

其次,對使用散劑分包裝置900將散劑分包之情形時之程序進行說明。 Next, a procedure for the case where the powder is divided by the powder dispensing device 900 will be described.

將散劑分包之作業係由藥劑師依照醫師之處方箋操作散劑分包裝置900而進行。即,藥劑師確認醫師之處方箋,自未圖示之藥架取出裝有所開處方之散劑之藥瓶。然後,使用天平等秤而量出所開處方之特定之散劑之總重量。例如若為一次服用量3g,早、中、晚一天服用3次,且服用7天,則量出63g之散劑。 The operation of dispensing the powder is performed by the pharmacist in accordance with the physician's practice of the powder dispensing device 900. That is, the pharmacist confirms the doctor's prescription and takes out the vial containing the prescribed powder from the medicine rack not shown. Then, using the equal weight scale, the total weight of the prescribed powder is determined. For example, if it is taken in a single dose of 3 g, taken three times a day in the morning, in the middle, and in the evening, and taken for 7 days, 63 g of the powder is measured.

然後,將量出之散劑投入給粉器901之料斗905。 Then, the measured powder is put into the hopper 905 of the powder feeder 901.

又,同時,對給粉器901之壓電元件(未圖示)通電而使槽910振動,進而,使分配盤912以固定之旋轉速度連續地旋轉。 At the same time, the piezoelectric element (not shown) of the powder feeder 901 is energized to vibrate the groove 910, and the distribution disk 912 is continuously rotated at a fixed rotational speed.

被投入至料斗905之散劑自料斗905之下端之開口落入給粉器901之槽910。然後,藉由槽910振動,而使散劑緩慢地向前端側移動,從而掉落至分配盤912。 The powder that is put into the hopper 905 falls from the opening of the lower end of the hopper 905 into the groove 910 of the powder feeder 901. Then, by the vibration of the groove 910, the powder is slowly moved toward the front end side to be dropped to the distribution tray 912.

另一方面,由於分配盤912係以特定之速度連續地旋轉,因此自槽910掉落之散劑均勻地分散於分配盤912之槽916中。 On the other hand, since the distribution tray 912 is continuously rotated at a specific speed, the powder dropped from the groove 910 is uniformly dispersed in the groove 916 of the distribution tray 912.

當散劑對分配盤912之掉落結束時,使分配盤912之旋轉停止。並且,其後,使刮出裝置915之刮集板917落至分配盤912之槽916內。進而其後,使分配盤912旋轉與分配個數相應之角度,將一次服用量之散劑集中於刮集板917之前表面側。然後,使刮集板917旋轉,藉由刮出板918而將散劑刮出至分配盤912外,並且投入包裝用料斗920。自包裝用料斗920掉落之散劑係藉由包裝裝置921而包裝。 When the dispensing of the powder to the dispensing tray 912 ends, the rotation of the dispensing tray 912 is stopped. Further, thereafter, the scraping plate 917 of the scraping device 915 is dropped into the groove 916 of the distribution tray 912. Thereafter, the distribution tray 912 is rotated at an angle corresponding to the number of dispenses, and the powder of one dose is concentrated on the front surface side of the scraping plate 917. Then, the scraping plate 917 is rotated, and the powder is scraped out to the outside of the distribution tray 912 by scraping the plate 918, and is put into the packaging hopper 920. The powder dropped from the packaging hopper 920 is packaged by the packaging device 921.

又,於專利文獻2中,揭示有能以散劑之處方量視服用時期而不同之方式輸入,從而對一包之包裝中所含之散劑之量賦予變化的方法。 Further, Patent Document 2 discloses a method in which the amount of the powder contained in the package of one pack can be changed by inputting the amount of the powder in a different manner depending on the administration period.

專利文獻2中揭示之方法係使分配盤912旋轉,將一次服用量之散劑集中於刮集板917之前表面側時,使分配盤912之旋轉量(旋轉角度)根據所開處方之量而不同,從而對集中於刮集板917之前表面側之散劑量賦予變化。 The method disclosed in Patent Document 2 rotates the distribution tray 912, and when the powder of one dose is concentrated on the front surface side of the scraping plate 917, the amount of rotation (rotation angle) of the distribution tray 912 is different depending on the amount of prescription prescribed. Thereby, a change is imparted to the scattered dose concentrated on the front side of the scraping plate 917.

根據專利文獻2中揭示之方法,可應對如早服用量1.2克、中服用量1.2克、晚服用量2.4克之不均勻處方而包裝散劑。 According to the method disclosed in Patent Document 2, it is possible to cope with an uneven preparation such as an early dose of 1.2 g, a medium dose of 1.2 g, and a late dose of 2.4 g.

先前技術文獻 Prior technical literature 專利文獻 Patent literature

專利文獻1:日本專利特開平7-80043號公報 Patent Document 1: Japanese Patent Laid-Open No. Hei 7-80043

專利文獻2:日本專利特開2004-305721號公報 Patent Document 2: Japanese Patent Laid-Open Publication No. 2004-305721

先前技術之散劑分包裝置900於將散劑分成多個小份而進行包裝之情形時發揮效力。又,可較佳地用於一次服用量較多之情形。 The prior art powder dispensing device 900 is effective in the case where the powder is packaged by dividing it into a plurality of small portions. Further, it can be preferably used in a case where the amount of one-time administration is large.

然而,先前技術之散劑分包裝置900不適用於一服(一包)之容量較少,且如2服用量、或3服用量之包數較少之情形時的分包。 However, the prior art powder dispensing device 900 is not suitable for subcontracting when the capacity of one serving (one pack) is small, and if the amount of 2 doses, or the number of packs of 3 doses is small.

例如,處方為小兒用之藥劑多為一次服用量之藥劑為1g以下之情形,服用如0.3g之極少量之藥劑之情形亦並不罕見。 For example, it is not uncommon for a prescription for a child to be administered in a single dose of less than 1 g. It is not uncommon to take a very small amount of a medicament such as 0.3 g.

又,由於小兒無法準確地向醫師傳達自身之症狀,因此醫師難以選擇適當之藥劑。因此,多數情況為醫師每天改變處方之藥劑之種類或量,觀察小兒患者之病情而選擇適當之藥劑。 Moreover, since the child cannot accurately convey the symptoms to the doctor, it is difficult for the doctor to select an appropriate medicine. Therefore, in most cases, the physician changes the type or amount of the prescribed drug every day, and observes the condition of the pediatric patient to select an appropriate agent.

於此種情形時,醫師每天變更處方,例如若為早、中、晚3次服用之藥劑,則會開出3包量之處方。然後,藥劑師使用散劑分包裝置900,依照處方箋而準備3包藥劑。 In this case, the physician changes the prescription every day. For example, if the medicine is taken three times in the morning, in the middle, or in the evening, the amount of the three packs will be opened. Then, the pharmacist uses the powder dispensing device 900 to prepare three packets of the drug in accordance with the prescription.

於此種情形時投入至分配盤912之藥劑之總量較少。因此,當使散劑自槽910掉落,而使散劑均勻地分散於分配盤912之槽916中時, 僅於槽916之底部淺淺地積存散劑。 In this case, the total amount of the medicament that is put into the distribution tray 912 is small. Therefore, when the powder is dropped from the groove 910 and the powder is uniformly dispersed in the groove 916 of the distribution tray 912, The powder is accumulated shallowly only at the bottom of the groove 916.

又,由於散劑係均勻地分散於分配盤912之槽916之全周,因此當分割為3次服用時,必須使分配盤912逐次旋轉1/3周而將散劑刮集於刮集板917之前表面,從而分配時之分配盤912之旋轉角度較大。 Further, since the powder is uniformly dispersed throughout the circumference of the groove 916 of the distribution tray 912, when divided into three doses, the distribution tray 912 must be rotated one-third by one turn to scrape the powder before the scraping plate 917. The surface, and thus the dispensing disc 912, has a larger angle of rotation when dispensed.

如此,於散劑淺淺地積存於槽916之底部,且刮集時之分配盤912之旋轉角度較大之情形時,不可忽視附著於槽916之底部之藥劑之量。 Thus, when the powder is stored shallowly at the bottom of the groove 916, and the rotation angle of the distribution plate 912 at the time of scraping is large, the amount of the drug attached to the bottom of the groove 916 cannot be ignored.

即,附著於槽916之底部之藥劑之量與積存於槽916之藥劑之深度無關而為固定。因此,分包一次服用量之藥劑時之藥劑損失量依存於刮集時之分配盤912之旋轉角度,於刮集時分配盤912之旋轉角度較大之情形時,一次服用量之藥劑之減少量較多。 That is, the amount of the drug attached to the bottom of the groove 916 is fixed irrespective of the depth of the drug stored in the groove 916. Therefore, the amount of the medicine lost when the medicine is administered in one dose depends on the rotation angle of the distribution tray 912 at the time of scraping, and when the rotation angle of the distribution tray 912 is large at the time of scraping, the amount of the medicine in one dose is reduced. More quantity.

又,如上所述,於一次服用量之藥劑量較少之情形時,殘留於槽916之底部之藥劑之比率相對較高。因此,於一次服用量之藥劑量較少之情形時,有一包內之內容量少於處方量之虞。 Further, as described above, the ratio of the drug remaining at the bottom of the tank 916 is relatively high when the dose of the single dose is small. Therefore, in the case where the dose of one dose is small, the amount of content in one pack is less than the amount of the prescription.

又,根據專利文獻2中揭示之方法,可應對如早服用量1.2克、中服用量1.2克、晚服用量2.4克之量不均勻處方而包裝散劑,但無法實施質不均勻處方。即,於專利文獻2中揭示之方法中,無法製作如於早服用量之包裝中封入散劑X、Y、Z,於中服用量之包裝中僅封入散劑Z,於晚服用量之包裝中封入散劑X、Y的質不同之3服用量之包裝。 Further, according to the method disclosed in Patent Document 2, it is possible to cope with an uneven dosage of 1.2 g of an early dose, 1.2 g of a middle dose, and 2.4 g of a late dose, but it is not possible to carry out a qualitative uneven prescription. That is, in the method disclosed in Patent Document 2, it is not possible to prepare the powder X, Y, and Z in the package of the early dosage, and only the powder Z is enclosed in the package of the middle dosage, and is enclosed in the package of the late dosage. Packing of 3 different doses of powder X and Y.

因此,本發明著眼於先前技術之上述問題,其課題在於:提供一種即便於一服(一包)之內容量較少、且分割數較少之情形時,亦可於一次服用量之包中裝入準確量之藥劑的分藥裝置及分藥方法。 Accordingly, the present invention has been made in view of the above problems of the prior art, and an object of the present invention is to provide a package that can be loaded in a single dose even when the amount of content of one package (one package) is small and the number of divisions is small. A dispensing device and a dispensing method for an accurate amount of the drug.

又,本發明之課題在於:提供一種亦可應對量不均勻處方、或質不均勻處方之分藥裝置及分藥方法。 Further, an object of the present invention is to provide a dispensing device and a dispensing method which can also cope with an uneven amount of prescription or a non-uniform prescription.

用以解決上述課題之態樣係一種分藥裝置,其具有:給藥器,其排出散劑;分配盤,其藉由動力而旋轉;刮出裝置,其刮出投入分配盤之散劑;及藥劑包裝裝置;且自給藥器對分配盤供給散劑,藉由刮出裝置將分配盤上之散劑按一次服用量逐次地刮出並投入藥劑包裝裝置,而按一次服用量逐次地包裝散劑;且該分藥裝置之特徵在於:上述給藥器可監視散劑之排出量而排出所需量之散劑,且能夠以分散配置模式運轉,該分散配置模式係自給藥器按一次服用量逐次地對分配盤供給散劑,其間使分配盤停止或旋轉而將散劑按一次服用量逐次地隔開間隔而配置於分配盤上。 A method for solving the above problems is a dispensing device having: an applicator that discharges a powder; a dispensing plate that is rotated by power; a scraping device that scrapes off a powder that is put into the dispensing plate; and a medicament a packaging device; and the powder is supplied to the dispensing tray from the applicator, and the powder on the dispensing tray is scraped out one by one by the scraping device and put into the medicine packaging device, and the powder is successively packaged in one dose; The dispensing device is characterized in that the applicator can monitor the discharge amount of the powder to discharge the required amount of the powder, and can be operated in a distributed configuration mode, which is to sequentially dispense the disc from the applicator in one dose. The powder is supplied, and the dispensing tray is stopped or rotated, and the powder is placed on the distribution tray at intervals in a single dose.

於本態樣之分藥裝置中,自給藥器按一次服用量逐次地對分配盤供給散劑。然後,其間使分配盤之旋轉停止,或以極小之角速度旋轉。因此,散劑係於一點或極窄之區域聚集成堆,從而形成散劑群。 In the dispensing device of the present aspect, the dispensing device is supplied with a powder from the dispenser in a single dose. Then, the rotation of the distribution tray is stopped or rotated at a very small angular velocity. Therefore, the powder is aggregated into a pile at a point or a very narrow area to form a powder group.

再者,散劑群通常形成複數個,但亦可僅形成一個散劑群。 Furthermore, the powder group usually forms a plurality of powders, but it is also possible to form only one powder group.

其後,使分配盤旋轉而以刮出裝置刮集散劑,進而,散劑自分配盤被刮出,但於本態樣之分藥裝置中,刮集藥劑時分配盤之旋轉角度較小,分配盤中殘留之藥劑之量較少。因此,於一包中封入準確量之藥劑。 Thereafter, the dispensing tray is rotated to scrape the powder by the scraping device, and further, the powder is scraped from the dispensing tray. However, in the dispensing device of the present aspect, the dispensing angle of the dispensing tray is small when the medicine is scraped, and the dispensing tray The amount of the remaining agent is small. Therefore, an accurate amount of the drug is enclosed in one package.

較理想為於分散配置模式下,當自給藥器對分配盤供給散劑時使分配盤之旋轉停止,當自給藥器將一次服用量之散劑供給至分配盤時,暫時地停止自給藥器對分配盤供給散劑,其後,使分配盤之旋轉以特定角度旋轉,進而其後,重新開始自給藥器對分配盤供給散劑,反覆進行該一連串動作。 Preferably, in the distributed configuration mode, when the self-administrator supplies the powder to the dispensing tray to stop the rotation of the dispensing tray, when the self-administrator supplies a dose of the powder to the dispensing tray, the dispensing of the self-administering device is temporarily stopped. The disc is supplied with a powder, and thereafter, the rotation of the dispensing tray is rotated at a specific angle, and thereafter, the powder is supplied from the dispenser to the dispensing tray, and the series of operations are repeated.

較理想為上述給藥器包含藥劑容器、及本體裝置,上述藥劑容器相對於本體裝置裝卸自如,於上述藥劑容器存在排出藥劑之藥劑排出部,本體裝置具有振動台、使振動台振動之加振器件、將藥劑容器暫時地固定於振動台之容器保持器件、及直接地或間接地測定藥劑容 器之重量的重量測定器件;且可將藥劑容器載置於振動台,藉由容器保持器件將藥劑容器固定於振動台,使振動台振動而自藥劑排出部逐次少量地排出散劑,並藉由重量測定器件而檢測散劑之排出量。 Preferably, the applicator includes a drug container and a main body device, and the drug container is detachably attached to the main body device, and the drug container has a drug discharge portion for discharging the drug, and the main device has a vibration table and vibrates the vibration table. a device, a container holding device for temporarily fixing the drug container to the vibration table, and measuring the drug capacity directly or indirectly The weight measuring device of the weight of the device; and the drug container can be placed on the vibrating table, and the container is fixed to the vibrating table by the container holding device, so that the vibrating table vibrates and the powder is discharged from the drug discharging portion in a small amount, and by the powder The weight measuring device detects the discharge amount of the powder.

於本態樣之分藥裝置中,於本體裝置固定藥劑容器。藉由於該狀態下使振動台振動,而可使藥劑容器之整體或一部分振動。因此,藥劑容器內之藥劑緩慢地向藥劑排出部側移動,藥劑經整流,其流動層流化,而自藥劑排出部排出。 In the dispensing device of the present aspect, the drug container is fixed to the body device. By vibrating the vibrating table in this state, the entire or a part of the drug container can be vibrated. Therefore, the medicine in the drug container is gradually moved to the drug discharge portion side, the drug is rectified, and the fluidized bed is fluidized and discharged from the drug discharge portion.

又,於容器載置裝置中,裝備有重量測定器件,因此可檢測藥劑之排出量,從而可使測量散劑等之作業自動化。 Further, since the container mounting device is equipped with the weight measuring device, the discharge amount of the drug can be detected, and the operation of measuring the powder or the like can be automated.

較理想為本發明之分藥裝置具備計量功能,即,藉由重量測定器件,測定排出藥劑以前之藥劑容器之重量即原重量,當自藥劑容器逐次少量排出散劑時,藉由上述重量測定器件而監視藥劑容器之重量,當藥劑容器之當前之重量即現重量與自原重量減去目標排出量所得之值一致時或大致一致時,使散劑自藥劑容器之排出停止。 Preferably, the dispensing device of the present invention has a metering function, that is, the weight of the drug container before discharge of the drug, that is, the original weight, is measured by the weight measuring device, and the weight measuring device is used when the powder is discharged a small amount from the drug container. The weight of the drug container is monitored, and when the current weight of the drug container, that is, the current weight, coincides with or substantially coincides with the value obtained by subtracting the target discharge amount from the original weight, the discharge of the powder from the drug container is stopped.

附帶說明藥劑容器之重量之測定器件,藥劑容器之重量之測定為直接或間接均可。即,可僅直接測定藥劑容器之重量,亦可測定包含振動台等機器在內之重量。 The measuring device for describing the weight of the drug container may be measured directly or indirectly by the weight of the drug container. That is, the weight of the drug container can be directly measured, and the weight including the machine such as the vibrating table can be measured.

於本態樣之分藥裝置中,利用排出藥劑以前之藥劑容器之重量即原重量、與藥劑容器之當前之重量即現重量,當現重量與自原重量減去目標排出量所得之值一致時使振動台之振動停止。或考慮到掉落途中之藥劑之重量,當現重量略少於自原重量減去目標排出量所得之值,或與該值大致一致時使振動台之振動停止。因此,於目標量之藥劑排出後,使振動台之振動停止,從而使藥劑之排出停止。 In the dispensing device of the present aspect, the weight of the drug container before discharge of the drug, that is, the original weight, and the current weight of the drug container, that is, the current weight, when the current weight is equal to the value obtained by subtracting the target discharge amount from the original weight The vibration of the vibrating table is stopped. Or taking into account the weight of the medicine on the way to the drop, when the current weight is slightly less than the value obtained by subtracting the target discharge amount from the original weight, or substantially coincident with the value, the vibration of the vibration table is stopped. Therefore, after the target amount of the drug is discharged, the vibration of the vibrating table is stopped, and the discharge of the drug is stopped.

較理想為可於分藥裝置之內部設置容器保管裝置,進而設置容器移動器件,可藉由容器移動器件而自容器保管裝置取出特定之藥劑容器並載置於振動台,自藥劑容器排出散劑並投入分配盤,藉由刮出 裝置而將已投入至分配盤之散劑刮出並送至藥劑包裝區域側,藉由藥劑包裝裝置而包裝藥劑,且藉由容器移動器件而將排出結束之藥劑容器返回至容器保管裝置。 Preferably, the container storage device is disposed inside the dispensing device, and the container moving device is further disposed. The container can be removed from the container storage device by the container moving device and placed on the vibration table, and the powder is discharged from the drug container. Put into the distribution plate by scraping The device scrapes off the powder that has been put into the distribution tray and sends it to the side of the medicine packaging area, and the medicine is packaged by the medicine packaging device, and the medicine container that has been discharged is returned to the container storage device by the container moving device.

根據本態樣,可自動地進行藥劑容器之選擇、計量、分配、包裝及將藥劑容器返回至原位置之一連串作業。 According to this aspect, the selection, metering, dispensing, packaging, and returning of the medicament container to the original position can be automatically performed in series.

又,產生相同作用效果之態樣係一種分藥裝置,其具有:分配盤,其藉由動力而旋轉;刮出裝置,其刮出已投入至分配盤之散劑;及藥劑包裝裝置;且對分配盤供給散劑,藉由刮出裝置將分配盤上之散劑刮出並投入至藥劑包裝裝置,而按一次服用量逐次地包裝散劑,且該分藥裝置之特徵在於:能夠以分散配置模式運轉,該分散配置模式係按一次服用量逐次地或僅按一次服用量對分配盤供給散劑,其間使分配盤停止或旋轉而於分配盤上形成一個或複數個散劑群,於分配盤上且上述散劑群之周向兩側形成不存在散劑之空間區域;且藉由刮出裝置而刮出上述散劑群並投入至藥劑包裝裝置。 Further, the aspect in which the same effect is produced is a dispensing device having: a dispensing tray that is rotated by power; a scraping device that scrapes the powder that has been thrown into the dispensing tray; and a drug packaging device; The dispensing tray supplies the powder, and the powder on the dispensing tray is scraped out and put into the medicine packaging device by the scraping device, and the powder is successively packaged in a single dose, and the dispensing device is characterized in that it can be operated in a distributed configuration mode The dispersion configuration mode supplies the powder to the distribution tray in a single dose or in a single dose, during which the distribution tray is stopped or rotated to form one or a plurality of powder groups on the distribution tray, and on the distribution tray. A space region where no powder is present is formed on both sides of the powder group; and the powder group is scraped off by the scraping device and put into the drug packaging device.

於本態樣之分藥裝置中,亦於一點或極窄之區域將散劑聚集成堆。 In the dispensing device of this aspect, the powder is also aggregated into a pile in a little or very narrow area.

其後,使分配盤旋轉而以刮出裝置刮集散劑,進而散劑自分配盤被刮出,但於本態樣之分藥裝置中,刮集藥劑時分配盤之旋轉角度較小,且分配盤中殘留之藥劑之量較少。因此,於一包中封入準確量之藥劑。 Thereafter, the dispensing tray is rotated to scrape the powder by the scraping device, and the powder is scraped from the dispensing tray. However, in the dispensing device of the present aspect, the dispensing disk has a smaller rotation angle when the medicament is scraped, and the dispensing tray The amount of the remaining agent is small. Therefore, an accurate amount of the drug is enclosed in one package.

較理想為本發明之分藥裝置具有清掃分配盤之清掃裝置,於以分散配置模式進行運轉後,藉由清掃裝置而清掃分配盤時,至少清掃存在過散劑之部位或區域。 Preferably, the dispensing device of the present invention has a cleaning device for cleaning the distribution tray. After the operation is performed in the distributed arrangement mode, when the distribution tray is cleaned by the cleaning device, at least the portion or region where the powder is present is cleaned.

根據本態樣,由於對分配盤進行清掃,因此防止藥劑之污染。又,較理想為於以分散配置模式進行運轉後進行之清掃係以存在有散劑之部位或區域為重點進行。例如,僅對存在有散劑之部位或區域進 行清掃,或將毛刷等接觸存在有散劑之部位或區域之時間設定為較與其他區域接觸之時間長。 According to this aspect, since the dispensing tray is cleaned, contamination of the medicament is prevented. Further, it is preferable that the cleaning performed after the operation in the distributed arrangement mode is focused on the portion or region in which the powder is present. For example, only the part or area where the powder is present The cleaning is performed, or the time at which the brush or the like is in contact with the portion or region where the powder is present is set to be longer than the contact with other regions.

較理想為於分散配置模式下,可使對分配盤供給之一次服用量之散劑之量個別地變化,且可使複數配置於分配盤上之一次服用量之散劑群中混合存在不同量之散劑群。 Preferably, in the distributed configuration mode, the amount of the powder to be supplied to the dispensing tray can be individually changed, and a plurality of powders can be mixed in a single dose of the powder group disposed on the dispensing tray. group.

本態樣係可應對量不均勻處方之分藥裝置。 This aspect is a dispensing device that can cope with an uneven amount of prescription.

又,本發明之分藥裝置亦可具有複數個給藥器,且作為分散配置模式下之動作之一,有混合模式,於混合模式下,將自一個給藥器排出之散劑與自其他給藥器排出之散劑供給至分配盤之相同部位或接近之部位,將自一個給藥器排出之散劑與自其他給藥器排出之散劑設為一個混合藥劑群,一併藉由刮出裝置刮出。 Moreover, the dispensing device of the present invention may have a plurality of applicators, and as one of the actions in the distributed arrangement mode, there is a mixing mode, and in the mixed mode, the powder discharged from one applicator is given to the other. The powder discharged from the medicine device is supplied to the same portion or close to the distribution tray, and the powder discharged from one dispenser and the powder discharged from other dispensers are set as a mixed medicament group, and scraped together by a scraping device. Out.

根據本態樣,可使複數種散劑混合存在於一包中。 According to this aspect, a plurality of powders can be mixed and present in one package.

推薦於混合模式下,可個別地變更要被驅動之給藥器、與自給藥器排出之散劑之量,從而形成混合狀態不同之混合藥劑群。 It is recommended that in the mixed mode, the amount of the powder to be driven and the powder discharged from the dispenser can be individually changed to form a mixed drug group having a different mixed state.

根據本態樣,亦可應對例如早服用量、中服用量、晚服用量般存在應於複數個時期服用之藥劑,且於各時期服用之藥劑之種類或量不同的情形。 According to this aspect, for example, the amount of the drug to be administered in a plurality of periods, such as the amount of early administration, the amount of administration, and the amount of late administration, may be used, and the type or amount of the agent to be administered at each period may be different.

推薦於混合模式下,可執行同時使複數個給藥器進行動作之同時排出動作,其後,使分配盤旋轉固定角度,使與先用於排出之給藥器不同的給藥器相對地接近先排出之散劑附近,從而自已接近之給藥器排出散劑。 It is recommended that in the hybrid mode, a plurality of applicators can be simultaneously operated while the discharge operation is performed, and thereafter, the dispensing tray is rotated at a fixed angle so that the applicator different from the applicator previously used for discharge is relatively close. The powder is discharged first, so that the powder is discharged from the applicator that is approaching.

根據本態樣,能夠於短時間內結束分包作業。 According to this aspect, the subcontracting operation can be ended in a short time.

較理想為可使分配盤反向旋轉,且於混合模式下,可自給藥器排出散劑並將散劑配置於分配盤之複數個部位,其後,使分配盤反向旋轉,使與先用於排出之給藥器不同的給藥器相對地接近先配置之散劑附近,從而自已接近之給藥器排出散劑。 Preferably, the dispensing disc can be rotated in the reverse direction, and in the mixing mode, the powder can be discharged from the applicator and the powder can be disposed in a plurality of portions of the dispensing tray, after which the dispensing tray is rotated in the reverse direction to be used first. The different applicators of the ejected applicator are relatively close to the vicinity of the previously disposed powder, thereby expelling the powder from the applicator that is approaching.

又,關於分藥方法之態樣係一種分藥方法,其特徵在於:其係使用分藥裝置而分裝藥劑之分藥方法,該分藥裝置具備:給藥器,其排出散劑;分配盤,其藉由動力而旋轉;刮出裝置,其刮出已投入至分配盤之散劑;及藥劑包裝裝置;且該分藥方法係按一次服用量逐次地對分配盤供給散劑,其間使分配盤停止或旋轉而將散劑按一次服用量逐次地隔開間隔而分散配置於分配盤上,藉由刮出裝置將分散配置之散劑逐群地刮出並送至藥劑包裝區域側,藉由藥劑包裝裝置而按一次服用量逐次地將藥劑包裝並排出。 Further, the aspect of the medicine dispensing method is a medicine dispensing method characterized in that it is a medicine dispensing method using a medicine dispensing device, the medicine dispensing device comprising: an applicator for discharging a powder; and a dispensing plate Rotating device that scrapes out the powder that has been thrown into the dispensing tray; and the drug packaging device; and the dispensing method supplies the dispensing plate to the dispensing plate in a single dose, with the dispensing plate being dispensed Stopping or rotating, the powder is dispersed and arranged on the distribution tray at intervals of one dose, and the scattered powders are scraped out in groups by the scraping device and sent to the side of the medicine packaging area by the medicine packaging. The device is packaged and discharged one by one in a single dose.

較理想為於自給藥器對分配盤供給散劑時,使分配盤之旋轉停止或使其以極低速旋轉,當自給藥器將一次服用量之散劑供給至分配盤時,暫時地停止自給藥器對分配盤供給散劑,其後,使分配盤旋轉特定之角度,進而其後,重新開始自給藥器對分配盤供給散劑,反覆進行該一連串動作。 Preferably, when the powder is supplied to the dispensing tray from the applicator, the rotation of the dispensing tray is stopped or rotated at a very low speed, and the self-administrator is temporarily stopped when the dose is supplied to the dispensing tray from the dispenser. The dispensing disc is supplied with a powder, and thereafter, the dispensing tray is rotated by a specific angle, and thereafter, the dispensing of the powder from the dispenser by the dispenser is resumed, and the series of operations are repeated.

亦可於分配盤上形成複數個散劑群,上述散劑群均為同一患者應服用之散劑。 A plurality of powder groups may also be formed on the distribution plate, and the powder groups are all powders to be taken by the same patient.

根據本態樣,不會弄錯應投藥之患者。 According to this aspect, patients who are supposed to be administered will not be mistaken.

相反地,亦可於分配盤上形成複數個散劑群,且於該散劑群中混合存在有不同患者應服用之散劑群。 Conversely, a plurality of powder groups may be formed on the distribution tray, and a powder group to be taken by different patients may be mixed in the powder group.

根據本態樣,分裝藥劑之效率提昇。 According to this aspect, the efficiency of dispensing the medicament is improved.

亦可使自給藥器排出之一次服用量之散劑之量變化,從而使形成於分配盤上之複數個散劑群中混合存在不同量之散劑群。 The amount of the powder to be administered from the applicator can also be varied so that a different amount of the powder group is mixed in the plurality of powder groups formed on the distribution tray.

亦推薦使用複數個給藥器,將自一個給藥器排出之散劑與自其他給藥器排出之散劑供給至分配盤之相同部位或接近之部位,將自一個給藥器排出之散劑與自其他給藥器排出之散劑設為一個混合散劑群,一併藉由刮出裝置刮出。 It is also recommended to use a plurality of applicators to supply the powder discharged from one applicator and the powder discharged from other applicators to the same part or close to the distribution plate, and to discharge the powder from one applicator. The powder discharged from other applicators is set as a mixed powder group, which is scraped together by a scraping device.

較理想為自給藥器排出散劑並將散劑配置於分配盤之複數個部 位,其後使分配盤反向旋轉,使與先用於排出之給藥器不同的給藥器相對地接近先配置之散劑附近,從而自已接近之給藥器排出散劑。 It is preferred to discharge the powder from the applicator and dispose the powder in a plurality of parts of the distribution plate The position, which in turn causes the dispensing tray to rotate in the opposite direction, causes the dispenser, which is different from the previously used dispenser, to be relatively close to the vicinity of the previously disposed powder, thereby expelling the powder from the applicator that is approaching.

亦可個別地變更要被驅動之給藥器、及自給藥器排出之散劑之量,從而形成混合狀態不同之混合藥劑群。 The amount of the powder to be driven and the amount of the powder discharged from the applicator can be individually changed to form a mixed drug group having a different mixed state.

根據本發明之分藥裝置及分藥方法,即便於一次服用量(一包)之容量較少、且分割數較少之情形時,亦可於一次服用量之包中裝入準確量之藥劑。 According to the dispensing device and the dispensing method of the present invention, even when the capacity of one dose (one pack) is small and the number of divisions is small, an accurate amount of the medicament can be loaded into the pack of one dose. .

1‧‧‧分藥裝置 1‧‧‧ dispensing device

2‧‧‧藥劑容器 2‧‧‧pharmaceutical container

2x‧‧‧藥劑容器 2x‧‧‧ drug container

2y‧‧‧藥劑容器 2y‧‧‧pharmaceutical container

2z‧‧‧藥劑容器 2z‧‧‧pharmaceutical container

3‧‧‧容器載置裝置(本體裝置) 3‧‧‧Container mounting device (body device)

5‧‧‧給藥器 5‧‧‧Applicator

6‧‧‧固定用鐵板部 6‧‧‧Fixed iron plate department

7‧‧‧殼體 7‧‧‧Shell

8‧‧‧藥劑排出部 8‧‧‧Drug Discharge Department

15‧‧‧資訊記錄構件 15‧‧‧Information Recording Component

20‧‧‧振動台 20‧‧‧Shape table

21‧‧‧加振器件 21‧‧‧Vibration device

22‧‧‧散劑(散劑群) 22‧‧‧ powder (dispersion group)

23‧‧‧散劑(散劑群) 23‧‧‧ powder (dispersion group)

24‧‧‧散劑(散劑群) 24‧‧‧ powder (dispersion group)

25‧‧‧重量測定器件 25‧‧‧ Weight measuring device

30a、30b‧‧‧磁鐵(容器保持器件) 30a, 30b‧‧‧ magnets (container holding devices)

31、32、33‧‧‧混合藥劑群 31, 32, 33‧‧‧ mixed drug groups

35‧‧‧混合藥劑群 35‧‧‧ Mixed drug group

36‧‧‧混合藥劑群 36‧‧‧ Mixed drug group

37‧‧‧混合藥劑群 37‧‧‧mixed drug group

45、46、47‧‧‧混合藥劑群 45, 46, 47‧ ‧ mixed drug groups

55、56、57‧‧‧混合藥劑群 55, 56, 57‧ ‧ mixed drug groups

100‧‧‧藥劑架部區域 100‧‧‧ Pharmacy area

101‧‧‧容器保管裝置 101‧‧‧Container storage device

102‧‧‧轉筒構件 102‧‧‧Turner components

103‧‧‧容器設置部 103‧‧‧ Container Setting Department

157‧‧‧搬運用鐵板部 157‧‧‧Electric iron plate for handling

200‧‧‧藥劑分割區域 200‧‧‧Pharmaceutical division

201‧‧‧分配盤 201‧‧‧Distribution disk

202‧‧‧散劑分配裝置 202‧‧‧Dispensing device

208‧‧‧藥劑投入槽 208‧‧‧Pharmaceutical input slot

211‧‧‧盤旋轉機構 211‧‧‧ disk rotating mechanism

241‧‧‧開口 241‧‧‧ openings

300‧‧‧藥劑包裝區域 300‧‧‧Pharmaceutical packaging area

410‧‧‧藥劑包裝裝置 410‧‧‧Pharmaceutical packaging device

413‧‧‧料斗 413‧‧‧ hopper

500‧‧‧清掃裝置 500‧‧‧ cleaning device

502‧‧‧清掃毛刷 502‧‧‧ Cleaning brush

503‧‧‧毛刷罩 503‧‧‧Brush brush cover

600‧‧‧刮出裝置 600‧‧‧Scrapping device

605‧‧‧刮出用臂 605‧‧‧Scratch arm

606‧‧‧刮出機構 606‧‧‧Scrapping agency

607‧‧‧刮出板 607‧‧‧Scratch board

609‧‧‧刮集板 609‧‧‧ scraping board

700‧‧‧容器移動器件 700‧‧‧Container mobile device

701‧‧‧升降機構 701‧‧‧ Lifting mechanism

702‧‧‧機器人 702‧‧‧Robot

705、706‧‧‧臂構件 705, 706‧‧‧ arm members

707‧‧‧手部 707‧‧‧Hands

900‧‧‧分包裝置 900‧‧‧Subcontracting device

901‧‧‧給粉器 901‧‧‧Food feeder

902‧‧‧散劑分配裝置 902‧‧‧Dispensing device

903‧‧‧藥劑包裝裝置 903‧‧‧Pharmaceutical packaging device

905‧‧‧料斗 905‧‧‧ hopper

910‧‧‧槽 910‧‧‧ slots

912‧‧‧分配盤 912‧‧‧Distribution disk

915‧‧‧刮出裝置 915‧‧‧Scratch device

916‧‧‧槽 916‧‧‧ slot

917‧‧‧刮集板 917‧‧‧ scraping board

918‧‧‧刮出板 918‧‧‧Scratch board

919‧‧‧馬達 919‧‧‧Motor

920‧‧‧包裝用料斗 920‧‧‧Package hopper

921‧‧‧包裝裝置 921‧‧‧Packing device

X‧‧‧散劑 X‧‧‧ powder

Y‧‧‧散劑 Y‧‧‧ powder

Z‧‧‧散劑 Z‧‧‧ powder

圖1係透視表示本發明之實施形態之分藥裝置之內部的立體圖。 Fig. 1 is a perspective view showing the inside of a dispensing device according to an embodiment of the present invention.

圖2(a)~(c)係按步驟對圖1之分藥裝置之作用進行說明的說明圖,左側係分配盤附近之剖視圖,右側係分配盤之俯視圖。 2(a) to 2(c) are explanatory views for explaining the action of the dispensing device of Fig. 1 in a stepwise manner, the left side is a cross-sectional view in the vicinity of the distribution tray, and the right side is a plan view of the distribution tray.

圖3(d)~(g)係按步驟對繼圖2之步驟後之分藥裝置之作用進行說明的說明圖,左側係分配盤附近之剖視圖,右側係分配盤之俯視圖。 3(d) to (g) are explanatory views for explaining the action of the dispensing device following the step of Fig. 2, the left side is a cross-sectional view in the vicinity of the distribution plate, and the right side is a plan view of the distribution plate.

圖4(h)~(i)係按步驟對圖1之分藥裝置之其他作用進行說明之說明圖,左側係分配盤附近之剖視圖,右側係分配盤之剖視圖。 4(h) to (i) are explanatory views for explaining other actions of the dispensing device of Fig. 1 in a stepwise manner, the left side is a cross-sectional view in the vicinity of the distribution plate, and the right side is a sectional view of the distribution plate.

圖5係給藥器之立體圖。 Figure 5 is a perspective view of the applicator.

圖6係藥劑容器之剖視圖。 Figure 6 is a cross-sectional view of the medicament container.

圖7係容器載置裝置(本體裝置)之立體圖。 Fig. 7 is a perspective view of a container mounting device (body device).

圖8係取圖7之容器載置裝置(本體裝置)之縱剖面而觀察之立體圖。 Fig. 8 is a perspective view showing a longitudinal section of the container mounting device (main body device) of Fig. 7.

圖9係取圖7之容器載置裝置(本體裝置)之縱剖面而觀察之側視圖。 Fig. 9 is a side elevational view of the container mounting device (body device) of Fig. 7 as viewed in a longitudinal section.

圖10係按步驟對混合模式下之圖1之分藥裝置之作用進行說明的說明圖,上側係分配盤之俯視圖,下側係盛放於分配盤之特定區域之散劑之剖視圖。 Fig. 10 is an explanatory view for explaining the action of the dispensing device of Fig. 1 in the mixing mode, in which the upper side is a plan view of the distribution tray, and the lower side is a cross-sectional view of the powder contained in a specific area of the distribution tray.

圖11係按步驟對混合模式之另一實施形態中之圖1之分藥裝置之作用進行說明的說明圖,上側係分配盤之俯視圖,下側係盛放於分配盤之特定區域之散劑之剖視圖。 Figure 11 is an explanatory view for explaining the action of the dispensing device of Figure 1 in another embodiment of the mixing mode, wherein the upper side is a plan view of the distribution tray, and the lower side is a powder which is contained in a specific area of the distribution tray. Cutaway view.

圖12係按步驟對混合模式之又一實施形態中之圖1之分藥裝置之作用進行說明的說明圖,上側係分配盤之俯視圖,下側係盛放於分配盤之特定區域之散劑之剖視圖。 Fig. 12 is an explanatory view for explaining the action of the dispensing device of Fig. 1 in another embodiment of the mixing mode, wherein the upper side is a plan view of the distribution tray, and the lower side is a powder which is contained in a specific area of the distribution tray. Cutaway view.

圖13係按步驟對混合模式之又一實施形態中之圖1之分藥裝置之作用進行說明的說明圖,上側係分配盤之俯視圖,下側係盛放於分配盤之特定區域之散劑之剖視圖。 Fig. 13 is an explanatory view for explaining the action of the dispensing device of Fig. 1 in still another embodiment of the mixing mode, wherein the upper side is a plan view of the distribution tray, and the lower side is a powder which is contained in a specific area of the distribution tray. Cutaway view.

圖14係對先前技術之分藥裝置之構成進行說明之說明圖。 Fig. 14 is an explanatory view for explaining the configuration of the dispensing device of the prior art.

以下,對本發明之實施形態之分藥裝置1進一步進行說明。 Hereinafter, the dispensing device 1 according to the embodiment of the present invention will be further described.

本實施形態之分藥裝置1係如下裝置,其可選擇收容有處方箋所記載之散劑之藥劑容器2,將其搬送,自藥劑容器2排出所需量之散劑,按一次服用量逐次地進行分割,並按一次服用量逐次地進行包裝,且其可自動地進行該等一連串作業。 The dispensing device 1 of the present embodiment is a device that can select a drug container 2 containing a powder described in a prescription, transport it, and discharge a required amount of the powder from the drug container 2, and perform the administration in a single dose. The segments are divided and packaged one by one in a single dose, and they can be automatically performed in a series of operations.

本實施形態之分藥裝置1如圖1所示般被殼體7包圍,其內部被分為藥劑架部區域100、藥劑分割區域200、及藥劑包裝區域300。 The dispensing device 1 of the present embodiment is surrounded by a casing 7 as shown in Fig. 1, and its inside is divided into a drug rack portion region 100, a drug dividing region 200, and a drug packaging region 300.

於藥劑架部區域100中,設置有供設置藥劑容器2之容器保管裝置101。於本實施形態中,容器保管裝置101具有沿大致水平方向旋轉之縱型之轉筒構件102,於轉筒構件102之外周面設置有複數個容器設置部103。容器設置部103係藉由機械卡合而保持藥劑容器2,可藉由壓入藥劑容器2而以機械卡合保持藥劑容器2,且當拉拽藥劑容器2時卡合脫開而使藥劑容器2脫離。 In the medicine rack portion region 100, a container storage device 101 for providing the drug container 2 is provided. In the present embodiment, the container storage device 101 has a vertical drum member 102 that rotates in a substantially horizontal direction, and a plurality of container installation portions 103 are provided on the outer peripheral surface of the drum member 102. The container setting portion 103 holds the drug container 2 by mechanical engagement, and can hold the drug container 2 by mechanically pressing the drug container 2, and can be disengaged when the drug container 2 is pulled to make the drug container 2 detached.

轉筒構件102係藉由馬達而旋轉,使所需之藥劑容器2接近下述機器手,藉由機器手進行裝卸。 The drum member 102 is rotated by a motor, and the required drug container 2 is brought close to the robot hand described below, and is attached and detached by a robot hand.

藥劑容器2與下述容器載置裝置(本體裝置)3構成一組給藥器5。 The drug container 2 and the container mounting device (body device) 3 described below constitute a group of applicators 5.

於藥劑容器2中,如圖5、圖6所示,於兩面設置有鐵板。設置於一面之鐵板係磁性附著於機器手而用以將藥劑容器2固定於機器手之搬運用鐵板部157。設置於另一面之鐵板係用以將藥劑容器2固定於設置在分配盤附近之容器載置裝置3之固定用鐵板部6。 In the drug container 2, as shown in Figs. 5 and 6, an iron plate is provided on both surfaces. The iron plate provided on one side is magnetically attached to the robot hand to fix the drug container 2 to the handling iron plate portion 157 of the robot hand. The iron plate provided on the other side is for fixing the drug container 2 to the fixing iron plate portion 6 of the container mounting device 3 provided in the vicinity of the distribution plate.

又,於藥劑容器2中,安裝有RFID(Radio Frequency IDentification,射頻識別)等資訊記錄構件15。 Further, an information recording member 15 such as an RFID (Radio Frequency IDentification) is attached to the drug container 2.

於藥劑容器2中,填充有所需之散劑,於上述RFID等資訊記錄構件15中,記錄有該散劑之名稱、有效期限、收納位置等各種資訊。 The drug container 2 is filled with a desired powder, and various information such as the name, expiration date, and storage position of the powder is recorded in the information recording member 15 such as the RFID.

如圖1所示,於藥劑架部區域100至藥劑分割區域200之區域中,設置有容器移動器件700。容器移動器件700係於沿垂直方向設置之升降機構701設置有機器人702者。機器人702具有2根臂構件705、706、及手部707。於手部707設置有磁鐵,可磁性附著藥劑容器2之鐵板而予以保持。 As shown in FIG. 1, a container moving device 700 is provided in a region from the drug rack portion region 100 to the drug dividing region 200. The container moving device 700 is provided with a robot 702 provided in a lifting mechanism 701 disposed in a vertical direction. The robot 702 has two arm members 705 and 706 and a hand 707. A magnet is provided in the hand 707, and the iron plate of the drug container 2 is magnetically attached and held.

藥劑分割區域200係以埋設狀態設置有2個分配盤201之區域,且於其周圍配置有容器載置裝置3、及清掃裝置500。於本實施形態中,於分配盤201之周圍配置有複數個容器載置裝置3。更具體而言,於分配盤201之周圍各設置有3台容器載置裝置3。 The drug division region 200 is a region in which two distribution trays 201 are provided in an embedded state, and a container mounting device 3 and a cleaning device 500 are disposed around the drug storage device. In the present embodiment, a plurality of container mounting devices 3 are disposed around the distribution tray 201. More specifically, three container mounting devices 3 are provided around the distribution tray 201.

又,於藥劑分割區域200設置有刮出裝置600。刮出裝置600包含刮出用臂605、及設置於其前端之刮出機構606。刮出機構606與公知者同樣地包含碟狀之刮集板609、及設置於刮集板609之刮出板607。 Further, a scraping device 600 is provided in the medicine divided region 200. The scraping device 600 includes a scraping arm 605 and a scraping mechanism 606 provided at a tip end thereof. Similarly to the well-known person, the scraping mechanism 606 includes a dish-shaped scraping plate 609 and a scraping plate 607 provided on the scraping plate 609.

於本實施形態中,自藥劑分割區域200之各分配盤201突出有刮出裝置600之刮出用臂605。 In the present embodiment, the scraping arm 605 of the scraping device 600 protrudes from each of the distribution trays 201 of the drug division region 200.

分配盤201可藉由盤旋轉機構211(圖2)而以固定速度旋轉。又,亦可使其旋轉特定之角度。分配盤201可向正方向亦可向反方向旋轉。 The distribution tray 201 can be rotated at a fixed speed by the disk rotation mechanism 211 (Fig. 2). Alternatively, it can be rotated at a specific angle. The distribution tray 201 can be rotated in the positive direction or in the reverse direction.

如圖7、8、9所示,容器載置裝置3具有振動台20、及直接地或間接地測定藥劑容器2之重量的重量測定器件25。又,設置有未圖示之掉落確認感測器。 As shown in Figs. 7, 8, and 9, the container mounting device 3 has a vibrating table 20 and a weight measuring device 25 for directly or indirectly measuring the weight of the drug container 2. Further, a drop confirmation sensor (not shown) is provided.

於振動台20,設置有將藥劑容器2暫時地固定於振動台20之容器保持器件。容器保持器件具體而言係磁鐵30a、30b。於振動台20之兩端,以傾斜姿勢安裝有加振器件21。加振器件21具體而言係壓電元件。掉落確認感測器例如為光電感測器,且係用以確認是否自藥劑容器2排出藥劑之感測器。 The shaker table 20 is provided with a container holding device that temporarily fixes the drug container 2 to the vibration table 20. The container holding device is specifically a magnet 30a, 30b. At both ends of the vibrating table 20, a vibration absorbing member 21 is attached in an inclined posture. The vibration absorbing device 21 is specifically a piezoelectric element. The drop confirmation sensor is, for example, a photo-sensitometer and is used to confirm whether or not the sensor of the medicament is discharged from the drug container 2.

於本實施形態中,可於容器載置裝置3載置藥劑容器2,使振動台20振動而自藥劑容器2排出藥劑。又,此時藥劑容器2之重量變化係藉由重量測定器件25而檢測。 In the present embodiment, the drug container 2 can be placed on the container mounting device 3, and the vibration table 20 can be vibrated to discharge the drug from the drug container 2. Further, at this time, the weight change of the drug container 2 is detected by the weight measuring device 25.

清掃裝置500具有清掃用臂,該清掃用臂以分配盤201附近為基端呈懸臂狀突出並且前端側藉由動力而升降,且於該清掃裝置500之前端設置有清掃毛刷502。 The cleaning device 500 includes a cleaning arm that protrudes in a cantilever shape with the vicinity of the distribution tray 201 as a base end, and the front end side is lifted and lowered by power, and a cleaning brush 502 is provided at the front end of the cleaning device 500.

清掃毛刷502係可旋轉地安裝於毛刷罩503內。毛刷罩503係前端側開口之罩,且自該開口部露出清掃毛刷502之一部分。 The sweeping brush 502 is rotatably mounted within the brush cover 503. The brush cover 503 is a cover that is open at the distal end side, and a part of the cleaning brush 502 is exposed from the opening.

又,毛刷罩503連接於未圖示之抽吸裝置。 Further, the brush cover 503 is connected to a suction device (not shown).

於藥劑包裝區域300,內置有藥劑包裝裝置410。藥劑包裝裝置410與公知者同樣地為按一次服用量逐次地包裝藥劑之機械,且如公知般包含分包紙供給裝置、及包裝裝置。又,於包裝部設置有投入藥劑之散劑投入料斗413(圖2)。 A drug packaging device 410 is built in the drug packaging area 300. Similarly to the well-known person, the medicine packaging device 410 is a machine that sequentially packs medicines in a single dose, and includes a packet feeding device and a packaging device as is known. Further, a powder input hopper 413 (Fig. 2) for introducing a drug is provided in the packaging portion.

本實施形態之分藥裝置1可自動地進行如下動作:將藥劑容器2收容於容器保管裝置101;根據處方箋而選出藥劑容器2;自容器保管裝置101取出藥劑容器2並使其移動至分配盤201附近,而載置於容器載置裝置3;將特定量之藥劑投入至分配盤201;將藥劑分割而投入至藥劑包裝裝置410;以及將藥劑容器2返回至容器保管裝置101。 The dispensing device 1 of the present embodiment automatically performs an operation of accommodating the drug container 2 in the container storage device 101, selecting the drug container 2 based on the prescription ;, and taking the drug container 2 from the container storage device 101 and moving it to the distribution. In the vicinity of the tray 201, it is placed on the container mounting device 3; a specific amount of the medicine is put into the distribution tray 201; the medicine is divided and put into the medicine packaging device 410; and the drug container 2 is returned to the container storage device 101.

又,本實施形態之分藥裝置1於將藥劑投入分配盤201時,可與先前技術同樣地,以將散劑均勻地投入分配盤201而分割之均勻配置模式、與將散劑呈散點地投入而分割之分散配置模式進行運轉。 Further, in the dispensing device 1 of the present embodiment, when the medicine is put into the distribution tray 201, the powder can be uniformly placed in the distribution tray 201 and divided into a uniform arrangement pattern, and the powder can be scattered as in the prior art. The split distributed configuration mode operates.

首先,對均勻配置模式進行說明。 First, the uniform configuration mode will be described.

如上所述,於本實施形態之分藥裝置1中,使用多個藥劑容器2。藥劑容器2之數量達到多個,原則上於各藥劑容器2中填充不同種類之藥劑。藥劑容器2係安裝並保管於容器保管裝置101中。 As described above, in the dispensing device 1 of the present embodiment, a plurality of drug containers 2 are used. The number of the drug containers 2 is plural, and in principle, each of the drug containers 2 is filled with a different type of agent. The drug container 2 is attached and stored in the container storage device 101.

本實施形態之分藥裝置1根據處方箋而自動地選出藥劑容器2。具體而言,使容器保管裝置101之轉筒構件102旋轉,而使所需之藥劑容器2接近容器移動器件700。然後,藉由容器移動器件700之手部707保持藥劑容器2。然後,藉由設置於手部707之磁鐵而吸附設置於藥劑容器2之搬運用鐵板部157。 The dispensing device 1 of the present embodiment automatically selects the drug container 2 based on the prescription. Specifically, the drum member 102 of the container storage device 101 is rotated to bring the desired drug container 2 close to the container moving device 700. The medicament container 2 is then held by the hand 707 of the container moving device 700. Then, the iron plate portion 157 for transportation of the drug container 2 is adsorbed by the magnet provided in the hand 707.

然後,使臂構件705、706後退而拔出藥劑容器2,使臂構件705、706動作而將該藥劑容器2設置於容器載置裝置3之振動台20。 Then, the arm members 705 and 706 are retracted to pull out the drug container 2, and the arm members 705 and 706 are operated to mount the drug container 2 on the vibration table 20 of the container mounting device 3.

再者,於調配複數種藥劑並同時封入於一個包裝中之情形時,將複數個藥劑容器2設置於容器載置裝置3。 Further, when a plurality of kinds of medicines are dispensed and sealed in one package at the same time, a plurality of medicine containers 2 are placed in the container mounting device 3.

然後,使振動台20振動。其結果為,藥劑容器2之散劑緩慢地移動而自藥劑容器2排出並掉落至分配盤201。 Then, the vibration table 20 is vibrated. As a result, the powder of the drug container 2 is slowly moved and discharged from the drug container 2 and dropped to the distribution tray 201.

又,繼振動開始後使散劑分配裝置202之分配盤201旋轉。又,繼振動開始後測定藥劑容器2之重量。其間,監視藥劑容器2之重量,於散劑之總排出量成為所需重量時,使振動台20之振動停止。 Further, the distribution tray 201 of the powder dispensing device 202 is rotated after the start of the vibration. Further, the weight of the drug container 2 was measured after the start of the vibration. In the meantime, the weight of the drug container 2 is monitored, and when the total discharge amount of the powder becomes a desired weight, the vibration of the vibration table 20 is stopped.

其後,使分配盤201之旋轉停止。然後,使刮出用臂605搖動,使前端側下降而使刮出機構606下降,而將刮出機構606放入分配盤201之藥劑投入槽208內。 Thereafter, the rotation of the distribution tray 201 is stopped. Then, the scraping arm 605 is shaken to lower the distal end side to lower the scraping mechanism 606, and the scraping mechanism 606 is placed in the medicine input groove 208 of the distribution tray 201.

然後,使分配盤201旋轉與分配個數相應之角度,而將藥劑刮集於刮集板609。其後,使刮集板609旋轉,藉由刮出板607抄起藥劑使 其自分配盤201排出,而投入至藥劑投入開口241。 Then, the dispensing tray 201 is rotated at an angle corresponding to the number of dispenses, and the medicine is scraped on the scraping plate 609. Thereafter, the scraping plate 609 is rotated, and the medicine is scraped off by the scraping plate 607. It is discharged from the distribution tray 201 and is put into the medicine input opening 241.

被投入至藥劑投入開口241之藥劑(散劑)自散劑投入料斗413掉落而被搬送至藥劑包裝裝置410,藉由藥劑包裝裝置410進行包裝。 The medicine (dispensing agent) that has been introduced into the medicine input opening 241 is dropped from the powder input hopper 413, and is transported to the medicine packaging device 410, and packaged by the medicine packaging device 410.

依序反覆進行該動作,將分配盤201內之藥劑全部排出,並分別藉由藥劑包裝裝置410進行包裝。 This operation is repeated in sequence, and all the medicines in the distribution tray 201 are discharged, and are respectively packaged by the medicine packaging device 410.

當將分配盤201內之藥劑全部排出結束時,執行槽清掃動作。即,使清掃裝置500之清掃用臂轉動而使設置於前端之清掃毛刷502下降,將清掃毛刷502放入分配盤201之藥劑投入槽208內。 When the discharge of all the medicines in the distribution tray 201 is completed, the tank cleaning operation is performed. That is, the cleaning arm of the cleaning device 500 is rotated to lower the cleaning brush 502 provided at the tip end, and the cleaning brush 502 is placed in the medicine input groove 208 of the distribution tray 201.

然後,一面使清掃毛刷502旋轉,一面使分配盤201旋轉。 Then, while the cleaning brush 502 is rotated, the distribution tray 201 is rotated.

其結果為,殘留於分配盤201之藥劑投入槽208內的藥劑之殘渣被清掃毛刷502刮落,揚起之殘渣被抽吸器件抽吸。其結果為,藥劑投入槽208內得以清掃。 As a result, the residue of the drug remaining in the medicine input tank 208 of the distribution tray 201 is scraped off by the cleaning brush 502, and the raised residue is sucked by the suction device. As a result, the inside of the medicine input tank 208 can be cleaned.

於以均勻配置模式運轉後實施之槽清掃動作係遍及分配盤201之藥劑投入槽208全周而進行清掃。 The tank cleaning operation performed after the operation in the uniform arrangement mode is performed throughout the entire circumference of the medicine input tank 208 of the distribution tray 201.

又,與此並行地啟動容器移動器件700,將藥劑容器2返回至轉筒構件102之容器設置部103。 Further, the container moving device 700 is activated in parallel with this, and the drug container 2 is returned to the container setting portion 103 of the drum member 102.

其次,對於本實施形態特有之動作即分散配置模式,一面參照圖2、3、4一面進行說明。分散配置模式與均勻配置模式相比,僅對分配盤201投入藥劑之步驟不同,因此以不同點為重點進行說明,省略共同部分之說明。 Next, the operation of the present embodiment, that is, the distributed arrangement mode, will be described with reference to Figs. 2, 3, and 4. The distributed arrangement mode differs from the uniform arrangement mode in that only the steps of putting the medicine into the distribution tray 201 are different. Therefore, the description will be focused on the differences, and the description of the common parts will be omitted.

於以分散配置模式運轉之情形時,當使散劑自藥劑容器2掉落至分配盤201時,不使分配盤201旋轉。 In the case of operating in the distributed configuration mode, when the powder is dropped from the drug container 2 to the dispensing tray 201, the dispensing tray 201 is not rotated.

即,如圖2(b)所示,於使分配盤201靜止之狀態下,自藥劑容器2將散劑排出至分配盤201。更具體而言,將藥劑容器2設置於容器載置裝置3之振動台20,並使振動台20振動。 That is, as shown in FIG. 2(b), the powder is discharged from the drug container 2 to the distribution tray 201 while the distribution tray 201 is stationary. More specifically, the drug container 2 is placed on the vibration table 20 of the container mounting device 3, and the vibration table 20 is vibrated.

又,繼振動開始後測定藥劑容器2之重量。其間,監視藥劑容器 2之重量,當散劑之總掉落量成為一次服用量之重量時,使振動台20之振動停止。 Further, the weight of the drug container 2 was measured after the start of the vibration. In the meantime, monitoring the drug container The weight of 2 causes the vibration of the vibrating table 20 to stop when the total amount of falling of the powder becomes the weight of the single dose.

即,於上述均勻配置模式下,自藥劑容器2一次排出複數服用量之合計量之散劑,但於以分散配置模式運轉之情形時,僅使一次服用量之散劑掉落至分配盤201之藥劑投入槽208。 That is, in the above-described uniform arrangement mode, the powder of the total amount of the plurality of doses is discharged from the drug container 2 at a time, but when it is operated in the distributed arrangement mode, only the dose of the powder of one dose is dropped to the dispensing tray 201. The tank 208 is input.

此處,分配盤201保持靜止狀態,因此散劑之掉落地點不變,如圖2(b)所示,藥劑(散劑)22於藥劑投入槽208之一點積層成堆。 Here, the distribution tray 201 is kept in a stationary state, so that the drop position of the powder does not change. As shown in Fig. 2(b), the medicine (dispersion) 22 is piled up at one point of the medicine input tank 208.

當一次服用量之藥劑掉落結束時,使振動台20之振動停止,而中斷散劑之排出。 When the dose of the one-time dose is dropped, the vibration of the vibrating table 20 is stopped, and the discharge of the powder is interrupted.

然後,繼續使分配盤201略微旋轉。例如,使其旋轉5度至30度左右之角度。即,使分配盤201旋轉微小角度後,使分配盤201之旋轉停止。 Then, the distribution tray 201 is continuously rotated slightly. For example, it is rotated by an angle of about 5 to 30 degrees. That is, after the distribution tray 201 is rotated by a slight angle, the rotation of the distribution tray 201 is stopped.

其結果為,先堆積成之散劑22之堆如圖2(c)所示般沿周向移動,分配盤201之新槽面轉入至藥劑容器2之正下方。 As a result, the pile of the powder 22 stacked first is moved in the circumferential direction as shown in Fig. 2(c), and the new groove surface of the distribution tray 201 is transferred directly below the drug container 2.

然後,如圖3(d)所示,使振動台20之振動重新開始,僅使一次服用量之散劑23掉落至新分配盤201之新槽面。 Then, as shown in Fig. 3(d), the vibration of the vibrating table 20 is restarted, and only the powder 23 of one dose is dropped to the new groove surface of the new dispensing tray 201.

於該情形時,分配盤201亦保持靜止狀態,因此藥劑之掉落地點不變,散劑23於一點聚集成堆。 In this case, the dispensing tray 201 also remains stationary, so that the drop location of the medicament does not change and the powder 23 is gathered at one point.

當一次服用量之藥劑掉落結束時,使振動台20之振動再次停止,而中斷散劑之排出並且使分配盤201略微旋轉。先堆積成之散劑23之堆沿周向移動,分配盤201之新槽面轉入至藥劑容器2之正下方。 When the dose of the dose of one dose is ended, the vibration of the vibrating table 20 is stopped again, the discharge of the powder is interrupted and the dispensing tray 201 is slightly rotated. The pile of the powder 23 which is first stacked is moved in the circumferential direction, and the new groove surface of the distribution tray 201 is transferred directly below the drug container 2.

以下,反覆進行該步驟,於分配盤201之槽面形成例如3堆散劑(散劑群)22、23、24(圖3e)。 Hereinafter, this step is repeated to form, for example, three powders (dispersion groups) 22, 23, and 24 (Fig. 3e) on the groove surface of the distribution tray 201.

散劑群彼此之間如圖所示般隔開有間隔。因此,於散劑群彼此之間,有不存在散劑之空間區域26。若以散劑群為中心觀察,則於散劑群之周向兩側形成有不存在散劑之空間區域26。 The powder groups are spaced apart from each other as shown. Therefore, there is no spatial region 26 of the powder between the powder groups. When viewed as a center of the powder group, a space region 26 in which no powder is present is formed on both sides of the powder group.

於形成特定之量之散劑群後,使分配盤201旋轉而使最初之散劑群(散劑22)轉動至刮出用臂605附近,使刮出用臂605前端側下降而使刮出機構606下降,從而將刮出機構606放入分配盤201之藥劑投入槽208內。 After forming a specific amount of the powder group, the distribution tray 201 is rotated to rotate the first powder group (dispersion agent 22) to the vicinity of the scraping arm 605, and the tip end side of the scraping arm 605 is lowered to lower the scraping mechanism 606. Thus, the scraping mechanism 606 is placed in the medicament input slot 208 of the dispensing tray 201.

然後,使分配盤201於不會到達鄰接之散劑群(散劑23)之範圍內旋轉,藉由刮集板609之前表面而將最初之散劑群(散劑22)刮集。 Then, the distribution tray 201 is rotated within a range that does not reach the adjacent powder group (dispersion agent 23), and the first powder group (dispersion agent 22) is scraped off by scraping the front surface of the sheet 609.

進而,使刮集板609旋轉,藉由刮出板607抄起藥劑使其自分配盤201排出,從而將散劑22投入至藥劑投入開口241。 Further, the scraping plate 609 is rotated, and the medicine is taken up by the scraping plate 607 to be discharged from the distribution tray 201, whereby the powder 22 is introduced into the medicine input opening 241.

被投入至藥劑投入開口241散劑22自散劑投入料斗413掉落而被搬送至藥劑包裝裝置410,從而藉由藥劑包裝裝置410進行包裝。 The powder 22 that has been introduced into the medicine input opening 241 is dropped from the powder input hopper 413 and transported to the medicine packaging device 410, and is packaged by the medicine packaging device 410.

依序反覆進行該動作,將分配盤201內之藥劑全部排出,並分別藉由藥劑包裝裝置410進行包裝。 This operation is repeated in sequence, and all the medicines in the distribution tray 201 are discharged, and are respectively packaged by the medicine packaging device 410.

根據分散配置模式,由於藉由刮集板609而刮集藥劑時分配盤201之旋轉角度較小,因此附著於分配盤201之藥劑量較少。又,由於分配盤201之旋轉角度較小,因此刮出藥劑所需之時間較短即可。 According to the distributed arrangement mode, since the rotation angle of the distribution tray 201 is small when the medicine is scraped by the scraping plate 609, the amount of the medicine attached to the distribution tray 201 is small. Further, since the rotation angle of the distribution tray 201 is small, the time required for scraping the medicine can be short.

當分配盤201內之藥劑全部排出結束時,執行槽清掃動作。但是,於以分散配置模式運轉後實施之槽清掃動作係僅對分配盤201之藥劑投入槽208之一部分進行清掃。 When the discharge of all the medicines in the distribution tray 201 is completed, the tank cleaning operation is performed. However, the tank cleaning operation performed after the operation in the distributed arrangement mode only cleans a portion of the medicine input tank 208 of the distribution tray 201.

即,於分散配置模式之情形時,僅對分配盤201之藥劑投入槽208之一部分之區域投下散劑22、23、24。例如,於上述實施形態中,於分配盤201之槽面形成3堆散劑群(圖3e)。此處,散劑群所分佈之區域係槽之全周之四分之一左右、約90度之區域。因而,於以分散配置模式運轉後實施之槽清掃動作係僅對該約90度之區域及其附近部分進行清掃。 That is, in the case of the distributed arrangement mode, the powders 22, 23, 24 are dropped only on the portion of the dispensing tray 201 where the drug is introduced into the groove 208. For example, in the above embodiment, three powder groups are formed on the groove surface of the distribution tray 201 (Fig. 3e). Here, the area in which the powder group is distributed is about one quarter of the entire circumference of the groove, and is about 90 degrees. Therefore, the tank cleaning operation performed after the operation in the distributed arrangement mode only cleans the region of about 90 degrees and the vicinity thereof.

因此,可使清掃所需之時間大幅縮短。 Therefore, the time required for cleaning can be greatly shortened.

又,與此並行地啟動容器移動器件700,將藥劑容器2返回至轉 筒構件102之容器設置部103。 Further, in parallel with this, the container moving device 700 is activated to return the drug container 2 to the transfer. The container setting portion 103 of the tubular member 102.

於以上說明之實施形態中,於以分散配置模式進行運轉之情形時,形成3群散劑群,進行3服用量之分包,但分包之個數為任意,可為一個分包,亦可為10個以上。 In the embodiment described above, when the operation is performed in the distributed arrangement mode, three groups of powder groups are formed, and the amount of the three doses is divided, but the number of the packets is arbitrary, and may be one package. It is more than 10 pieces.

又,於以上說明之實施形態中,於以分散配置模式進行運轉後,僅對分配盤201之藥劑投入槽208之內設置有藥劑(散劑)之區域進行清掃。即,使以分散配置模式進行運轉後之清掃步驟簡化。作為進一步簡化之方法,亦可僅對曾設置散劑群之部位進行清掃。 Further, in the embodiment described above, after the operation is performed in the distributed arrangement mode, only the region in which the medicine (dispersion) is placed in the medicine input tank 208 of the distribution tray 201 is cleaned. That is, the cleaning step after the operation in the distributed arrangement mode is simplified. As a further simplification method, it is also possible to clean only the portion where the powder group has been set.

當然,亦可於以分散配置模式進行運轉後,對藥劑投入槽208遍及全周而進行清掃,但推薦對於設置有散劑之區域或曾設置散劑之部位,與其他區域或部位相比更仔細地進行清掃。例如,可考慮調整分配盤201之旋轉速度,使清掃裝置500之清掃毛刷502停留於設置有散劑之區域或曾設置散劑之部位的時間較長,或使分配盤201往返旋轉而使清掃裝置500之清掃毛刷502通過之次數比其他區域更多。 Of course, after the operation is performed in the distributed arrangement mode, the drug input tank 208 may be cleaned over the entire circumference. However, it is recommended that the area where the powder is disposed or the portion where the powder is disposed is more carefully compared with other areas or parts. Clean up. For example, it is conceivable to adjust the rotation speed of the distribution tray 201 so that the cleaning brush 502 of the cleaning device 500 stays in the area where the powder is disposed or the portion where the powder is disposed, or the distribution tray 201 is rotated back and forth to make the cleaning device. The cleaning brush 502 of 500 passes more times than other areas.

又,以上說明之實施形態中,以對同一患者投予之散劑進行分包為前提進行說明,各散劑群之藥劑量均相同。 Further, in the embodiment described above, the powder is administered to the same patient as a premise, and the amount of each powder group is the same.

然而,本發明並不限定於該使用方法,亦可同時對複數名患者投予之藥劑進行分包。 However, the present invention is not limited to the method of use, and it is also possible to subcontract a plurality of drugs administered by a patient at the same time.

例如,如圖4所示,第1散劑群(散劑27)係針對3歲之A患者所開處方者,藥劑量為0.3g。相對於此,第2散劑群(散劑28)係針對6歲之B患者所開處方者,藥劑量為0.8g。 For example, as shown in Fig. 4, the first powder group (dispersion 27) is a prescription for a 3-year-old A patient, and the dose is 0.3 g. On the other hand, the second powder group (dispersion 28) is a prescription for a 6-year-old B patient, and the dose is 0.8 g.

於同時進行針對複數名患者之處方之情形時,於下游側之藥劑包裝裝置410中,對包裝袋標註如「A患者用」、「B患者用」之區分患者名或服用時期等之印字,如此標示以使藥劑師不會產生投藥錯誤。 When the case of a plurality of patients is performed at the same time, in the drug packaging device 410 on the downstream side, the packaging bag is marked with a name such as "A patient use" or "B patient use", and the patient name or the administration period is printed. This is marked so that the pharmacist does not produce a medication error.

又,亦可集中開有同一種類之藥劑之處方箋,而一次分包複數名患者之散劑。 In addition, it is also possible to concentrate on the prescription of the same type of medicament, and to dispense the powder of a plurality of patients at a time.

藉由本實施形態之分藥裝置1,亦可應對量不均勻處方而包裝散劑。 According to the dispensing device 1 of the present embodiment, the powder can be packaged in response to an uneven amount of prescription.

該情形時之情況與圖4相同,因此併用圖4對應對量不均勻處方之方法進行說明。 The situation at the time of this case is the same as that of FIG. 4, and therefore, the method corresponding to the uneven amount of prescription is described with reference to FIG.

例如,於應對如早服用量1.2克、中服用量2.4克、晚服用量1.2克之不均勻處方而包裝散劑之情形時,於使分配盤201靜止之狀態下,自藥劑容器2對分配盤201排出早服用量1.2克之藥劑。更具體而言,將藥劑容器2設置於容器載置裝置3之振動台20,使振動台20振動並且監視藥劑容器2之重量,當散劑之總掉落量成為早服用量之1.2克時,使振動台20之振動停止。以此種方式形成之第1散劑群(散劑27)為早服用量之藥劑。 For example, in the case where the powder is packaged in an uneven prescription such as an early dose of 1.2 g, a medium dose of 2.4 g, and a late dose of 1.2 g, the dispensing tray 201 is dispensed from the drug container 2 while the dispensing tray 201 is stationary. Excrete an early dose of 1.2 grams of the drug. More specifically, the drug container 2 is placed on the vibration table 20 of the container mounting device 3, the vibration table 20 is vibrated and the weight of the drug container 2 is monitored, and when the total amount of the powder falls is 1.2 g of the early dose, The vibration of the vibrating table 20 is stopped. The first powder group (dispersion 27) formed in this manner is an early dose of the drug.

然後,繼續使分配盤201略微旋轉後,使分配盤201停止,自藥劑容器2對分配盤201排出中服用量2.4克之藥劑。即,將使振動台20振動之時間等設為不同,從而使自藥劑容器2對分配盤供給之一次服用量之散劑之量針對每個服用時期而個別地變化。以此種方式形成之第2散劑群(散劑28)為中服用量之藥劑。 Then, after the distribution tray 201 is continuously rotated slightly, the dispensing tray 201 is stopped, and the medicine container 2 discharges the medicine of 2.4 g in the dispensing tray 201. In other words, the time during which the vibration table 20 vibrates is set to be different, and the amount of the powder to be supplied from the drug container 2 to the dispensing disk is individually changed for each administration period. The second powder group (dispersion 28) formed in this manner is a medium dose.

藉由同樣之步驟形成晚服用量之散劑群(未圖示)。其結果為,於分配盤201中,混合存在有不同量之散劑群。其後之步驟係如上所述,將散劑27、28依序投入至藥劑投入開口241,並藉由藥劑包裝裝置410進行包裝。 A group of powders (not shown) for late administration is formed by the same procedure. As a result, in the distribution tray 201, a different amount of the powder group is mixed. The subsequent steps are as follows, and the powders 27, 28 are sequentially introduced into the drug input opening 241 and packaged by the drug packaging device 410.

於下游側之藥劑包裝裝置410中,對包裝袋標註如「早服用」、「中服用」之區分服用時期等之印字。 In the medicine packaging device 410 on the downstream side, the packaging bag is marked with a printing period such as "early taking" and "medium taking".

於上述實施形態中,列舉於一次服用量之包裝中封入一種散劑之情形為例進行說明,但亦可於一次服用量之包裝中同時封入複數種散劑。 In the above embodiment, a case in which a powder is enclosed in a package of one dose is described as an example, but a plurality of powders may be simultaneously enclosed in a package of one dose.

於在一次服用量之包裝中同時封入複數種散劑之情形時,藉由 混合模式而使分藥裝置1運轉。再者,混合模式係分散配置模式之一種形態。 By including a plurality of powders in a package of one dose at a time, by The dispensing mode is operated by the mixing mode. Furthermore, the mixed mode is one form of the distributed configuration mode.

以下,對於混合模式,一面參照圖10至13一面進行說明。 Hereinafter, the mixing mode will be described with reference to Figs. 10 to 13 .

為了方便說明,將分配盤201假想地劃分為A區域、B區域、C區域。又,於本實施形態中,使用3台容器載置裝置3,且於各容器載置裝置3設置藥劑容器2。為了方便說明,將3個藥劑容器2區分為藥劑容器2x、2y、2z。於各藥劑容器2x、2y、2z中收容有不同之散劑。為了便於理解,而以自左上向右下傾斜之斜線表示藥劑容器2x中收容之散劑X,以自右上向左下傾斜之斜線表示藥劑容器2y中收容之散劑Y,且以空白框表示藥劑容器2z中收容之散劑X。 For convenience of explanation, the distribution tray 201 is imaginarily divided into an A area, a B area, and a C area. Moreover, in this embodiment, three container mounting apparatuses 3 are used, and the medicine container 2 is provided in each container mounting apparatus 3. For convenience of explanation, the three drug containers 2 are divided into drug containers 2x, 2y, and 2z. Different powders are contained in each of the drug containers 2x, 2y, and 2z. For the sake of easy understanding, the powder X contained in the medicine container 2x is indicated by a diagonal line inclined from the upper left to the lower right, and the powder Y contained in the medicine container 2y is indicated by a diagonal line inclined from the upper right to the lower left, and the medicine container 2z is indicated by a blank frame. The powder X in the containment.

圖10係早服用量、中服用量、晚服用量之一天量,分包為3包之例,且各包裝內之散劑X之量相同。又,各包裝內之散劑Y之量亦相同。進而,各包裝內之散劑Z之量亦相同。為了便於圖示,各包裝內之散劑X之量、散劑Y之量及散劑Z之量表示為相同,但實際上該等之量不同。 Fig. 10 is an example of the amount of the morning dose, the medium dose, the late dose, and the subcontracting is 3 packs, and the amount of the powder X in each package is the same. Moreover, the amount of the powder Y in each package is also the same. Further, the amount of the powder Z in each package is also the same. For convenience of illustration, the amount of the powder X, the amount of the powder Y, and the amount of the powder Z in each package are expressed as the same, but actually the amounts are different.

於該情形時,如圖10之階段(1)所示,以使分配盤201之A區域來到藥劑容器2z之正下方之位置之方式旋轉分配盤201,於該位置使分配盤201之旋轉停止。 In this case, as shown in the stage (1) of Fig. 10, the distribution tray 201 is rotated in such a manner that the A area of the distribution tray 201 comes directly below the drug container 2z, and the rotation of the distribution tray 201 is made at this position. stop.

然後,於使分配盤201靜止之狀態下,自藥劑容器2z對分配盤201排出藥劑Z。更具體而言,使設置有藥劑容器2z之容器載置裝置3之振動台20振動。 Then, the medicine Z is discharged from the medicine container 2z to the distribution tray 201 while the distribution tray 201 is stationary. More specifically, the vibration table 20 of the container mounting device 3 provided with the drug container 2z is vibrated.

又,繼振動開始後測定藥劑容器2z之重量。其間,監視藥劑容器2z之重量,於散劑Z之總掉落量成為一次服用量之重量時,使振動台20之振動停止。 Further, the weight of the drug container 2z was measured after the start of the vibration. In the meantime, the weight of the drug container 2z is monitored, and when the total amount of drop of the powder Z is the weight of the single dose, the vibration of the vibrating table 20 is stopped.

然後,繼續使分配盤201略微旋轉,如圖10之階段(2)所示,於藥劑容器2z之正下方之位置存在分配盤201之B區域,且藥劑容器2y之正 下方之位置存在分配盤201之A區域的狀態下使分配盤201之旋轉停止。 Then, the distribution tray 201 is continuously rotated slightly, as shown in the stage (2) of FIG. 10, there is a B area of the distribution tray 201 at a position directly below the drug container 2z, and the drug container 2y is positive. The rotation of the distribution tray 201 is stopped in a state where the lower portion has the A area of the distribution tray 201.

然後,於使分配盤201靜止之狀態下,自藥劑容器2y及藥劑容器2z對分配盤201排出藥劑Z、藥劑Y。 Then, the medicine Z and the medicine Y are discharged from the medicine container 2y and the medicine container 2z to the distribution tray 201 while the distribution tray 201 is stationary.

其結果為,於A區域,於在先前之步驟中掉落之藥劑Z上,堆積自藥劑容器2y掉落之藥劑Y。 As a result, in the area A, the medicine Y dropped from the medicine container 2y is piled up on the medicine Z dropped in the previous step.

又,於分配盤201之B區域,藥劑Z自藥劑容器2z掉落。 Further, in the region B of the distribution tray 201, the medicine Z is dropped from the medicine container 2z.

然後,繼續使分配盤201進一步略微旋轉,如圖10之階段(3)所示,於藥劑容器2z之正下方之位置存在分配盤201之C區域,藥劑容器2y之正下方之位置存在分配盤201之B區域,且藥劑容器2x之正下方之位置存在分配盤201之A區域的狀態下,使分配盤201之旋轉停止。 Then, the distribution tray 201 is further rotated slightly further, as shown in the stage (3) of Fig. 10, there is a C area of the distribution tray 201 at a position directly below the medicine container 2z, and a distribution tray exists at a position directly below the medicine container 2y. In the region B of 201, and the position immediately below the drug container 2x exists in the region A of the distribution tray 201, the rotation of the distribution tray 201 is stopped.

然後,於使分配盤201靜止之狀態下,自藥劑容器2x、藥劑容器2y及藥劑容器2z對分配盤201排出藥劑Z、藥劑Y、藥劑X。 Then, the medicine Z, the medicine Y, and the medicine X are discharged from the medicine container 2x, the medicine container 2y, and the medicine container 2z to the distribution tray 201 while the distribution tray 201 is stationary.

其結果為,於A區域中,於在先前之步驟中掉落之藥劑Z、Y上,進而堆積自藥劑容器2x掉落之藥劑X。 As a result, in the A region, the drug X dropped from the drug container 2x is deposited on the medicines Z and Y dropped in the previous step.

又,於B區域中,於在先前之步驟中掉落之藥劑Z上,堆積自藥劑容器2y掉落之藥劑Y。 Further, in the region B, the medicine Y dropped from the medicine container 2y is deposited on the medicine Z dropped in the previous step.

進而,於分配盤201之C區域,藥劑Z自藥劑容器2z掉落。 Further, in the region C of the distribution tray 201, the medicine Z is dropped from the medicine container 2z.

然後,繼續使分配盤201進一步略微旋轉,如圖10之階段(4)所示,於藥劑容器2z之正下方之位置不存在分配盤201之A、B、C之任一區域,藥劑容器2y之正下方之位置存在分配盤201之C區域,藥劑容器2x之正下方之位置存在分配盤201之B區域的狀態下,使分配盤201之旋轉停止。 Then, the distribution tray 201 is further rotated slightly, as shown in the stage (4) of FIG. 10, there is no area of the distribution tray 201, A, B, C, directly below the medicament container 2z, and the medicament container 2y In the position immediately below, there is a C area of the distribution tray 201, and in a state where the position immediately below the medicine container 2x exists in the B area of the distribution tray 201, the rotation of the distribution tray 201 is stopped.

又,A區域離開各藥劑容器2x。 Further, the A area is separated from each of the drug containers 2x.

然後,於使分配盤201靜止之狀態下,自藥劑容器2x及藥劑容器2y對分配盤201排出藥劑Y、藥劑X。 Then, the medicine Y and the medicine X are discharged from the medicine container 2x and the medicine container 2y to the distribution tray 201 while the distribution tray 201 is stationary.

其結果為,於B區域,於在先前之步驟中掉落之藥劑Z、Y上,進而堆積自藥劑容器2x掉落之藥劑X。 As a result, in the region B, the medicines X dropped from the medicine container 2x are deposited on the medicines Z and Y dropped in the previous step.

又,於C區域,於在先前之步驟中掉落之藥劑Z上,堆積自藥劑容器2y掉落之藥劑Y。 Further, in the region C, the medicine Y dropped from the medicine container 2y is piled up on the medicine Z dropped in the previous step.

然後,繼續使分配盤201進一步略微旋轉,如圖10之階段(5)所示,於藥劑容器2z、2y之正下方之位置不存在分配盤201之A、B、C之任一區域,且藥劑容器2x之正下方之位置存在分配盤201之C區域的狀態下使分配盤201之旋轉停止。 Then, the distribution tray 201 is further rotated slightly, as shown in the stage (5) of FIG. 10, there is no area of the distribution tray 201, A, B, C, directly below the medicament containers 2z, 2y, and The rotation of the distribution tray 201 is stopped in a state where the C area of the distribution tray 201 exists in the position immediately below the medicine container 2x.

又,A區域與B區域離開各藥劑容器2x。 Further, the A area and the B area are separated from the respective drug containers 2x.

然後,於使分配盤201靜止之狀態下,自藥劑容器2x對分配盤201排出藥劑X。 Then, the medicine X is discharged from the medicine container 2x to the distribution tray 201 while the distribution tray 201 is stationary.

其結果為,於C區域,於在先前之步驟中掉落之藥劑Z、Y上,進而堆積自藥劑容器2x掉落之藥劑X。 As a result, in the region C, the medicines X dropped from the drug container 2x are deposited on the medicines Z and Y dropped in the previous step.

如此,於分配盤201之A區域、B區域、C區域,分別形成散劑X、Y、Z堆積而成之混合藥劑群31、32、33。 In this manner, the mixed drug groups 31, 32, and 33 in which the powders X, Y, and Z are stacked are formed in the A region, the B region, and the C region of the distribution tray 201, respectively.

後續步驟與上述通常之分散配置模式之動作相同,使分配盤201旋轉而將最初之混合藥劑群31、32、33逐個刮集,使刮集板609旋轉,藉由刮出板607抄起藥劑使其自分配盤201排出,將各藥劑群投入至藥劑投入開口241,並藉由藥劑包裝裝置410進行包裝。 The subsequent steps are the same as the above-described normal distributed arrangement mode, and the distribution tray 201 is rotated to scrape the first mixed drug groups 31, 32, and 33 one by one, and the scraping plate 609 is rotated to scrape the medicine by the scraping plate 607. The drug is discharged from the distribution tray 201, and each drug group is introduced into the drug input opening 241, and packaged by the drug packaging device 410.

於以上說明之實施形態中,表示於各包裝中封入相同量之散劑X、Y、Z之情形,但亦可使包裝之內容個別地變化。即,藉由本實施形態之分藥裝置1,亦可應對質不均勻處方而包裝散劑。 In the embodiment described above, the same amount of powders X, Y, and Z are enclosed in each package, but the contents of the package may be individually changed. In other words, according to the dispensing device 1 of the present embodiment, the powder can be packaged in response to the uneven quality prescription.

例如,亦可製作於早服用量之包裝中封入散劑X、Y、Z,於中服用量之包裝中僅封入散劑Z,且於晚服用量之包裝中封入散劑X、Y的3服用量之包裝。 For example, it is also possible to seal the powder X, Y, and Z in the package of the early dosage, and only the powder Z is enclosed in the package of the medium dosage, and the powder X and Y are enclosed in the package of the late dosage. package.

例如將A區域設為早服用量,將B區域設為中服用量,且將C區域 設為晚服用量而形成混合藥劑群35、36、37。 For example, set the A area to the early dose, the B area to the middle dose, and the C area. The mixed drug groups 35, 36, and 37 were formed in a late dose.

於該情形時,如圖11所示,於階段(3),省略自藥劑容器2y、2z掉落藥劑,而防止藥劑Y掉落至B區域(中服用量),又,防止藥劑Z掉落至C區域(晚服用量)。又,於階段(4),省略自藥劑容器2x掉落藥劑,而防止藥劑X掉落至B區域(中服用量)。 In this case, as shown in FIG. 11, in the stage (3), the medicine is dropped from the medicine containers 2y, 2z, and the medicine Y is prevented from falling to the B area (the amount taken), and the medicine Z is prevented from falling. To area C (late dose). Further, in the stage (4), the medicine is dropped from the medicine container 2x, and the medicine X is prevented from falling to the B area (the amount taken).

其結果為,於A區域,形成包含散劑X、Y、Z之混合藥劑群35,於B區域,形成僅散劑Z之藥劑群36。又,於C區域,形成散劑X、Y之混合藥劑群37。 As a result, in the A region, the mixed drug group 35 including the powders X, Y, and Z is formed, and in the B region, the drug group 36 containing only the powder Z is formed. Further, in the C region, the mixed drug group 37 of the powders X and Y is formed.

後續步驟與上述通常之分散配置模式之動作相同。 The subsequent steps are the same as the above-described usual distributed configuration mode.

又,亦可個別地變更包裝中內置之藥劑之量。 Further, the amount of the medicine built in the package can be individually changed.

例如,亦可進行如下等分包,即,於一天之服用量中,均封入散劑X、Y、Z,但於中服用量中,與其他相比散劑Y之處方量較多。即,亦可同時封入複數種散劑,進而應對量不均勻處方而包裝散劑。 For example, the sub-package may be carried out in such a manner that the powders X, Y, and Z are enclosed in the daily dose, but the amount of the powder Y is larger than that of the others in the middle dose. That is to say, a plurality of powders can be sealed at the same time, and the powder can be packaged in response to an uneven amount of prescription.

於該情形時,圖12所示,於階段(3),使自藥劑容器2y之藥劑掉落量變多。其結果為,於分配盤201之A區域、B區域、C區域分別形成散劑X、Y、Z堆積而成之混合藥劑群45、46、47,但B區域與其他區域相比散劑Y之量堆積得更多。 In this case, as shown in Fig. 12, in the stage (3), the amount of the medicine falling from the drug container 2y is increased. As a result, the mixed drug groups 45, 46, and 47 in which the powders X, Y, and Z are stacked are formed in the A region, the B region, and the C region of the distribution tray 201, but the amount of the powder Y is compared with the other regions. Stacked up more.

後續步驟與上述通常之分散配置模式之動作相同。 The subsequent steps are the same as the above-described usual distributed configuration mode.

圖10至圖12所示之例均揭示了使分配盤201向同一方向旋轉而進行分包的方法,但亦可使分配盤201向正反兩方向旋轉而形成混合藥劑群。 Each of the examples shown in FIGS. 10 to 12 discloses a method of subdividing the distribution tray 201 in the same direction, but the distribution tray 201 may be rotated in both the forward and reverse directions to form a mixed drug group.

圖13表示使分配盤201向正反兩方向旋轉而形成混合藥劑群之情形時的實施形態。 FIG. 13 shows an embodiment in a case where the distribution tray 201 is rotated in both the forward and reverse directions to form a mixed drug group.

於該情形時,於圖13之階段(1),成為藥劑容器2x之正下方之位置存在分配盤201之A區域,藥劑容器2y之正下方之位置存在分配盤201之B區域,且藥劑容器2z之正下方之位置存在分配盤201之C區域 的狀態。 In this case, in the stage (1) of FIG. 13, there is a region A of the distribution tray 201 at a position directly below the drug container 2x, a region B of the distribution tray 201 at a position directly below the drug container 2y, and a drug container. There is a C area of the distribution tray 201 at a position directly below 2z status.

然後,自各藥劑容器2x、2y、2z同時使散劑掉落。其結果為,散劑X掉落至A區域,散劑Y掉落至B區域,且散劑Z掉落至C區域。 Then, the powder is simultaneously dropped from each of the drug containers 2x, 2y, and 2z. As a result, the powder X falls to the A region, the powder Y falls to the B region, and the powder Z falls to the C region.

然後,繼續使分配盤201略微向正方向旋轉,如圖13之階段(2)所示,成為藥劑容器2x之正下方之位置存在分配盤201之B區域,藥劑容器2y之正下方之位置存在分配盤201之C區域,且藥劑容器2z之正下方之位置不存在任一區域的狀態。 Then, the distribution tray 201 is continuously rotated in the positive direction, as shown in the stage (2) of Fig. 13, the position B directly below the medicine container 2x exists in the area B of the distribution tray 201, and the position immediately below the medicine container 2y exists. The C area of the disc 201 is dispensed, and the position immediately below the medicine container 2z does not exist in any of the areas.

然後,自各藥劑容器2x、2y同時使散劑掉落。其結果為,於B區域,於在先前之步驟中掉落之藥劑Y上,堆積自藥劑容器2x掉落之藥劑X。又,於C區域,於在先前之步驟中掉落之藥劑z上,堆積自藥劑容器2y掉落之藥劑Y。 Then, the powder is simultaneously dropped from each of the drug containers 2x, 2y. As a result, in the region B, the medicine X dropped from the medicine container 2x is piled up on the medicine Y dropped in the previous step. Further, in the region C, the medicine Y dropped from the medicine container 2y is piled up on the medicine z dropped in the previous step.

然後,繼續使分配盤201進一步向略微正方向旋轉,如圖13之階段(3)所示,成為藥劑容器2x之正下方之位置存在分配盤201之C區域的狀態。 Then, the distribution tray 201 is further rotated in the slightly positive direction, and as shown in the stage (3) of FIG. 13, the C area of the distribution tray 201 exists in the position immediately below the medicine container 2x.

然後,自藥劑容器2x使散劑掉落。其結果為,於C區域,於在先前之步驟中掉落之藥劑Z、Y上堆積自藥劑容器2x掉落之藥劑X。 Then, the powder is dropped from the drug container 2x. As a result, in the region C, the medicine X dropped from the drug container 2x is deposited on the medicines Z and Y dropped in the previous step.

然後,繼續使分配盤201稍大幅地向反方向旋轉,如圖13之階段(4)所示,於藥劑容器2y之正下方之位置存在分配盤201之A區域,且藥劑容器2z之正下方之位置存在分配盤201之B區域的狀態下使分配盤201之旋轉停止。 Then, the distribution tray 201 is continuously rotated slightly in the reverse direction, as shown in the stage (4) of Fig. 13, there is a region A of the distribution tray 201 at a position directly below the drug container 2y, and directly below the drug container 2z. The rotation of the distribution tray 201 is stopped in a state where the B area of the distribution tray 201 exists.

然後,於使分配盤201靜止之狀態下,自藥劑容器2y及藥劑容器2z對分配盤201排出藥劑Y、Z。 Then, the medicines Y and Z are discharged from the drug container 2y and the drug container 2z to the distribution tray 201 while the distribution tray 201 is stationary.

其結果為,於B區域,於在先前之步驟中掉落之藥劑Y、X上,堆積自藥劑容器2z掉落之藥劑Z。又,於A區域,於在先前之步驟中掉落之藥劑X上,堆積自藥劑容器2y掉落之藥劑Y。 As a result, in the region B, the medicine Z dropped from the drug container 2z is deposited on the medicines Y and X dropped in the previous step. Further, in the area A, the medicine Y dropped from the medicine container 2y is piled up on the medicine X dropped in the previous step.

然後,繼續使分配盤201進一步略微向反方向旋轉,如圖13之階 段(5)所示,於藥劑容器2z之正下方之位置存在分配盤201之A區域的狀態下使分配盤201之旋轉停止。 Then, continue to rotate the distribution plate 201 further in the opposite direction, as shown in FIG. As shown in the paragraph (5), the rotation of the distribution tray 201 is stopped in a state where the A region of the distribution tray 201 is present at a position directly below the drug container 2z.

然後,於使分配盤201靜止之狀態下,自藥劑容器2z對分配盤201排出藥劑Z。 Then, the medicine Z is discharged from the medicine container 2z to the distribution tray 201 while the distribution tray 201 is stationary.

其結果為,於A區域,於在先前之步驟中掉落之藥劑X、Y上,堆積自藥劑容器2z掉落之藥劑Z。 As a result, in the region A, the medicine Z dropped from the drug container 2z is deposited on the medicines X and Y dropped in the previous step.

如此,於分配盤201之A區域、B區域、C區域分別形成散劑X、Y、Z堆積而成之混合藥劑群55、56、57。 In this manner, the mixed drug groups 55, 56, and 57 in which the powders X, Y, and Z are stacked are formed in the A region, the B region, and the C region of the distribution tray 201, respectively.

後續步驟與上述通常之分散配置模式之動作相同。 The subsequent steps are the same as the above-described usual distributed configuration mode.

於以上說明實施形態中,亦形成3群混合散劑群,而進行3服用量之分包,但對於分包之個數為任意,可為一個分包,亦可為10個以上。 In the above-described embodiment, three groups of mixed powder groups are formed, and the amount of the three doses is divided. However, the number of the packets is arbitrary, and may be one package or ten or more.

又,於以上說明之實施形態中,於同一區域內,在先掉落之藥劑上堆積新掉落之藥劑,但並非必須堆積藥劑,只要使其等集中掉落至接近之區域即可。 Further, in the embodiment described above, the newly dropped medicine is deposited on the first drop of the medicine in the same region, but it is not necessary to deposit the medicine, and it is only necessary to concentrate the drop to the close area.

即,於分散配置模式(包含混合模式)下,具有使分配盤201旋轉,而藉由刮集板609將藥劑刮集的步驟,因此只要使複數種藥劑集中於接近之區域,即可刮集複數種藥劑,而一併刮出。 That is, in the distributed arrangement mode (including the mixed mode), there is a step of rotating the distribution tray 201 and scraping the medicine by the scraping plate 609. Therefore, as long as a plurality of medicines are concentrated in the close area, the scraping can be performed. A plurality of medicines are scraped together.

於上述實施形態中,藉由容器載置裝置3與藥劑容器2而構成一組給藥器5,且採用監視散劑掉落量之構成。然而,本發明並不限定於該構成,例如亦可使用如先前技術所示之於槽910下設置未圖示之壓電元件而使槽910振動的構造之給粉器906。 In the above embodiment, the container placing device 3 and the drug container 2 constitute a group of the applicator 5, and a configuration for monitoring the amount of powder drop is employed. However, the present invention is not limited to this configuration. For example, a powder feeder 906 having a configuration in which a piezoelectric element (not shown) is provided under the groove 910 to vibrate the groove 910 as shown in the prior art may be used.

於該情形時,藥劑師量出特定量之散劑,將該散劑投入至料斗905而使其掉落至分配盤912內。 In this case, the pharmacist measures a specific amount of the powder, and the powder is put into the hopper 905 to be dropped into the distribution tray 912.

又,作為本發明之應進一步解決之課題,可列舉於以分散配置模式運轉之情形時,藥劑之掉落量變得不穩定之顧慮。 Moreover, as a subject to be further solved by the present invention, when the operation is performed in the distributed arrangement mode, the amount of falling of the medicine becomes unstable.

即,於本發明中,於以分散配置模式運轉之情形時,使容器載置裝置3振動而自藥劑容器2排出藥劑,當特定量之排出結束時,使容器載置裝置3之振動停止,進而,於經過固定時間後使容器載置裝置3振動而自藥劑容器2排出藥劑。 In other words, in the case of operating in the distributed arrangement mode, the container mounting device 3 vibrates and discharges the drug from the drug container 2, and when the discharge of the specific amount is completed, the vibration of the container mounting device 3 is stopped. Further, after a fixed period of time, the container mounting device 3 is vibrated to discharge the drug from the drug container 2.

此處,對藥劑容器2內之藥劑之動作進行研究,藥劑容器2係以縱向姿勢被保管,而內部之藥劑係以縱向姿勢為基準集中於容器底之部位,遠離藥劑排出口。 Here, the action of the medicine in the drug container 2 was examined, and the drug container 2 was stored in a vertical posture, and the medicine inside was concentrated on the bottom of the container with respect to the longitudinal posture, and was away from the drug discharge port.

而且,當容器載置裝置3開始振動時,如圖6所示,內部之藥劑緩慢地朝向藥劑排出口前進,最終自藥劑排出部8掉落。而且,藥劑於前進時被平整為層狀。 Further, when the container mounting device 3 starts to vibrate, as shown in FIG. 6, the internal medicine gradually advances toward the medicine discharge port, and finally falls from the medicine discharge portion 8. Moreover, the medicament is flattened into a layer shape as it advances.

然而,於第二次排出時,藥劑之前端部分已經到達藥劑排出部8。因此,第一次排出與第二次以後之排出的排出條件不同。 However, at the time of the second discharge, the front end portion of the medicine has reached the medicine discharge portion 8. Therefore, the discharge conditions of the first discharge and the discharge of the second time are different.

作為解決該問題之手段,考慮於第二次以後之排出開始時,改變振動模式而使容器載置裝置3進行動作,使藥劑暫時向容器底之部位移動。 As a means for solving this problem, in consideration of the start of discharge at the second and subsequent times, the vibration mode is changed, and the container mounting device 3 is operated to temporarily move the medicine to the portion of the container bottom.

又,亦可於第二次以後之排出開始時,藉由容器移動器件700之手部707保持藥劑容器2而使其暫時成為縱向姿勢,或使藥劑排出部8向上傾斜,其後再安裝藥劑容器2。藉由經過該步驟,而可使藥劑之前端部分後退,而第二次以後亦以相同排出條件排出藥劑,從而可實現高精度之分散配置。 Further, at the start of the second and subsequent discharges, the medicine container 2 may be temporarily held in the vertical posture by the hand 707 of the container moving device 700, or the medicine discharge portion 8 may be tilted upward, and then the medicine may be attached. Container 2. By this step, the front end portion of the medicine can be retracted, and the medicine can be discharged under the same discharge condition after the second time, so that a highly accurate dispersion configuration can be realized.

於上述實施形態中,於以分散配置模式自藥劑容器2對分配盤201投入藥劑時,使分配盤201之旋轉停止而進行,但亦可一面使分配盤201低速旋轉一面投入藥劑。 In the above-described embodiment, when the medicine is placed in the dispensing tray 201 from the drug container 2 in the dispersion arrangement mode, the rotation of the distribution tray 201 is stopped. However, the dispensing tray 201 can be rotated while rotating the dispensing tray 201.

2‧‧‧藥劑容器 2‧‧‧pharmaceutical container

3‧‧‧容器載置裝置(本體裝置) 3‧‧‧Container mounting device (body device)

22‧‧‧散劑(散劑群) 22‧‧‧ powder (dispersion group)

23‧‧‧散劑(散劑群) 23‧‧‧ powder (dispersion group)

24‧‧‧散劑(散劑群) 24‧‧‧ powder (dispersion group)

201‧‧‧分配盤 201‧‧‧Distribution disk

208‧‧‧藥劑投入槽 208‧‧‧Pharmaceutical input slot

211‧‧‧盤旋轉機構 211‧‧‧ disk rotating mechanism

241‧‧‧開口 241‧‧‧ openings

410‧‧‧藥劑包裝裝置 410‧‧‧Pharmaceutical packaging device

413‧‧‧料斗 413‧‧‧ hopper

605‧‧‧刮出用臂 605‧‧‧Scratch arm

606‧‧‧刮出機構 606‧‧‧Scrapping agency

607‧‧‧刮出板 607‧‧‧Scratch board

609‧‧‧刮集板 609‧‧‧ scraping board

Claims (19)

一種分藥裝置,其具有:給藥器,其排出散劑;分配盤,其藉由動力而旋轉;刮出裝置,其刮出已投入至分配盤之散劑;及藥劑包裝裝置;且自給藥器對分配盤供給散劑,藉由刮出裝置將分配盤上之散劑按一次服用量逐次地刮出並投入藥劑包裝裝置,而按一次服用量逐次地包裝散劑;且該分藥裝置之特徵在於:上述給藥器可監視散劑之排出量而排出所需量之散劑,且能夠以分散配置模式運轉,該分散配置模式係自給藥器以按一次服用量逐次地對分配盤供給散劑,其間使分配盤停止或旋轉而將散劑以按一次服用量逐次地隔開間隔地配置於分配盤上。 A dispensing device having: an applicator that discharges a powder; a dispensing tray that is rotated by power; a scraping device that scrapes a powder that has been thrown into the dispensing tray; and a drug packaging device; and a self-administering device The powder is supplied to the distribution tray, and the powder on the distribution tray is scraped off by the scraping device one by one and put into the medicine packaging device, and the powder is successively packaged in one dose; and the dispensing device is characterized by: The above-mentioned applicator can monitor the discharge amount of the powder to discharge the required amount of the powder, and can be operated in a distributed arrangement mode in which the dispensing device is supplied with the powder from the dispenser in a single dose, and the dispensing is performed therebetween. The disc is stopped or rotated, and the powder is placed on the distribution tray at intervals in a single dose. 如請求項1之分藥裝置,其中於分散配置模式下,當自給藥器對分配盤供給散劑時使分配盤之旋轉停止,當自給藥器將一次服用量之散劑供給至分配盤時,暫時地停止自給藥器對分配盤供給散劑,其後,使分配盤旋轉特定角度,進而其後,重新開始自給藥器對分配盤供給散劑,反覆進行該一連串動作。 The dispensing device according to claim 1, wherein in the distributed configuration mode, when the dispensing device supplies the powder to the dispensing tray, the rotation of the dispensing tray is stopped, and when the self-administering device supplies the powder in one dose to the dispensing tray, temporarily The supply of the powder to the dispensing tray is stopped by the applicator, and thereafter, the dispensing tray is rotated by a specific angle, and thereafter, the powder is supplied from the dispenser to the dispensing tray, and the series of operations are repeated. 如請求項1或2之分藥裝置,其中上述給藥器包含藥劑容器、及本體裝置,上述藥劑容器相對於本體裝置裝卸自如,上述藥劑容器具有排出藥劑之藥劑排出部,本體裝置具有振動台、使振動台振動之加振器件、將藥劑容器暫時地固定於振動台之容器保持器件、及直接地或間接地測定藥劑容器之重量的重量測定器件;且可將藥劑容器載置於振動台,藉由容器保持器件將藥劑容器固定於振動台,使振動台振動而自藥劑排出部逐次少量地排出散劑,並藉由重量測定器件而檢測散劑之排出量。 The dispensing device according to claim 1 or 2, wherein the applicator includes a drug container and a body device, wherein the drug container is detachably attached to the body device, the drug container has a drug discharging portion for discharging the drug, and the body device has a vibration table a vibration absorbing device for vibrating the vibration table, a container holding device for temporarily fixing the drug container to the vibration table, and a weight measuring device for directly or indirectly measuring the weight of the drug container; and the drug container can be placed on the vibration table The container holder fixes the drug container to the vibrating table, vibrates the vibrating table, and sequentially discharges the powder from the drug discharge portion a small amount, and detects the discharge amount of the powder by the weight measuring device. 如請求項3之分藥裝置,其中於該分藥裝置之內部設置容器保管裝置,進而設置有容器移動器件,可藉由容器移動器件而自容器保管裝置取出特定之藥劑容器並載置於振動台,自藥劑容器排出散劑並投入至分配盤,藉由刮出裝置而將已投入至分配盤之散劑刮出並送至藥劑包裝區域側,藉由藥劑包裝裝置而包裝藥劑,且可藉由容器移動器件而將排出結束之藥劑容器返回至容器保管裝置。 The dispensing device of claim 3, wherein a container storage device is disposed inside the dispensing device, and further a container moving device is provided, and the specific drug container can be taken out from the container storage device by the container moving device and placed in the vibration Disposing the powder from the drug container and putting it into the distribution tray, scraping the powder that has been put into the distribution tray and sending it to the side of the medicine packaging area by the scraping device, and packaging the medicine by the medicine packaging device, and The container moves the device and returns the discharged drug container to the container storage device. 一種分藥裝置,其具有:分配盤,其藉由動力而旋轉;刮出裝置,其刮出已投入至分配盤之散劑;及藥劑包裝裝置;且對分配盤供給散劑,藉由刮出裝置將分配盤上之散劑刮出並投入至藥劑包裝裝置,且按一次服用量逐次地包裝散劑;且該分藥裝置之特徵在於:能夠以分散配置模式運轉,該分散配置模式係按一次服用量逐次地或僅按一次服用量對分配盤供給散劑,其間使分配盤停止或旋轉而於分配盤上形成一個或複數個散劑群,於分配盤上且上述散劑群之周向兩側形成不存在散劑之空間區域,且藉由刮出裝置而刮出上述散劑群並將其投入至藥劑包裝裝置。 A dispensing device having: a dispensing tray that is rotated by power; a scraping device that scrapes a powder that has been thrown into the dispensing tray; and a drug packaging device; and supplies the dispensing disk with a powder by means of a scraping device Dissolving the powder on the dispensing tray and putting it into the medicine packaging device, and sequentially packaging the powder in a single dose; and the dispensing device is characterized in that it can be operated in a distributed configuration mode, which is a single dose Dispensing the dispensing discs one by one or only once, during which the dispensing tray is stopped or rotated to form one or a plurality of powder groups on the dispensing tray, and the circumferential sides of the powder group are not present on the distribution tray The space region of the powder is scraped off by the scraping device and put into the drug packaging device. 如請求項1至5中任一項之分藥裝置,其具有清掃分配盤之清掃裝置,於以分散配置模式進行運轉後,藉由清掃裝置而清掃分配盤時,至少清掃存在過散劑之部位或區域。 The dispensing device according to any one of claims 1 to 5, further comprising a cleaning device for cleaning the distribution tray, wherein after cleaning the distribution tray by the cleaning device after cleaning in the distributed arrangement mode, at least cleaning the portion where the powder is present Or area. 如請求項1至6中任一項之分藥裝置,其中於分散配置模式下,可使對分配盤供給之一次服用量之散劑之量個別地變化,且可使複數配置於分配盤上之一次服用量之散劑群中混合存在不同 量之散劑群。 The dispensing device according to any one of claims 1 to 6, wherein in the distributed configuration mode, the amount of the powder to be supplied to the dispensing tray can be individually changed, and the plural can be disposed on the dispensing tray. There is a difference in the mixture of powders in one dose. The amount of powder. 如請求項1至7中任一項之分藥裝置,其具有複數個給藥器,且作為分散配置模式下之動作之一,有混合模式,於混合模式下,將自一個給藥器排出之散劑與自其他給藥器排出之散劑供給至分配盤之相同部位或接近之部位,將自一個給藥器排出之散劑與自其他給藥器排出之散劑設為一個混合藥劑群,一併藉由刮出裝置刮出。 The dispensing device according to any one of claims 1 to 7, which has a plurality of applicators and has a mixed mode as one of the actions in the distributed configuration mode, and in the mixed mode, is discharged from a dispenser The powder and the powder discharged from other applicators are supplied to the same portion or close to the distribution tray, and the powder discharged from one dispenser and the powder discharged from other dispensers are set as a mixed medicament group. Scrape off by the scraping device. 如請求項8之分藥裝置,其中於混合模式下,可個別地變更要被驅動之給藥器、與自給藥器排出之散劑之量,從而形成混合狀態不同之混合藥劑群。 The dispensing device according to claim 8, wherein in the mixing mode, the amount of the powder to be driven and the powder discharged from the dispenser is individually changed to form a mixed drug group having a different mixed state. 如請求項8或9之分藥裝置,其中於混合模式下,可執行同時使複數個給藥器進行動作之同時排出動作,其後,使分配盤旋轉固定角度,使與先用於排出之給藥器不同的給藥器相對地接近先排出之散劑附近,從而自已接近之給藥器排出散劑。 The dispensing device according to claim 8 or 9, wherein in the mixing mode, the plurality of applicators can be simultaneously operated while the discharging operation is performed, and thereafter, the dispensing tray is rotated at a fixed angle to be used for discharging first. The different applicators of the applicator are relatively close to the vicinity of the first discharged powder, thereby expelling the powder from the applicator that is approaching. 如請求項8至10中任一項之分藥裝置,其中可使分配盤反向旋轉,且於混合模式下,可自給藥器排出散劑而將散劑配置於分配盤之複數個部位,其後,使分配盤反向旋轉,使與先用於排出之給藥器不同的給藥器相對地接近先配置之散劑附近,從而自已接近之給藥器排出散劑。 The dispensing device according to any one of claims 8 to 10, wherein the dispensing tray is reversely rotatable, and in the mixing mode, the powder can be discharged from the applicator to dispose the powder in a plurality of portions of the dispensing tray, thereafter The dispensing disc is rotated in the opposite direction so that the dispenser, which is different from the previously used dispenser, is relatively close to the vicinity of the previously disposed powder, thereby discharging the powder from the applicator that is approaching. 一種分藥方法,其特徵在於:其係使用分藥裝置而分裝藥劑之分藥方法,該分藥裝置具備:給藥器,其排出散劑;分配盤,其藉由動力而旋轉;刮出裝置,其刮出已投入至分配盤之散劑;及藥劑包裝裝置;且該分藥方法係按一次服用量逐次地對分配盤供給散劑,其間使分配盤停止或旋轉而將散劑群按一次服用量逐次地隔開間隔地分散配置於分配盤上,藉由刮出裝置而將分散配置之散劑群 逐群地刮出並送至藥劑包裝區域側,藉由藥劑包裝裝置而將藥劑按一次服用量逐次地包裝並排出。 A medicine dispensing method characterized in that it is a medicine dispensing method using a dispensing device, the medicine dispensing device comprising: an applicator that discharges a powder; a dispensing tray that is rotated by power; a device for scraping out a powder that has been thrown into the dispensing tray; and a drug packaging device; and the dispensing method is to supply the powder to the dispensing tray one by one in a single dose, during which the dispensing tray is stopped or rotated and the powder group is taken once Dispersely disposed on the distribution plate at intervals, and dispersedly disposed by the scraping device The scraping is carried out group by group and sent to the side of the medicine packaging area, and the medicine is packaged and discharged one by one by the medicine packaging device. 如請求項12之分藥方法,其中於自給藥器對分配盤供給散劑時,使分配盤之旋轉停止或使其以極低速旋轉,當自給藥器將一次服用量之散劑供給至分配盤時,暫時地停止自給藥器對分配盤供給散劑,其後,使分配盤旋轉特定角度,進而其後,重新開始自給藥器對分配盤供給散劑,反覆進行該一連串動作。 The method according to claim 12, wherein when the dispenser is supplied with a powder from the dispenser, the rotation of the dispensing tray is stopped or rotated at a very low speed, when the powder is supplied to the dispensing tray from the dispenser. The supply of the powder to the dispensing tray is temporarily stopped by the applicator, and thereafter, the dispensing tray is rotated by a specific angle, and thereafter, the powder is supplied from the dispenser to the dispensing tray, and the series of operations are repeated. 如請求項12或13之分藥方法,其中於分配盤上形成複數個散劑群,上述散劑群均為同一患者應服用之散劑。 The method according to claim 12 or 13, wherein a plurality of powder groups are formed on the distribution tray, and the powder group is a powder to be taken by the same patient. 如請求項12或13之分藥方法,其中於分配盤上形成複數個散劑群,於該散劑群中混合存在有不同患者應服用之散劑群。 The method according to claim 12 or 13, wherein a plurality of powder groups are formed on the distribution tray, and a powder group to be taken by different patients is mixed in the powder group. 如請求項12至15中任一項之分藥方法,其中使自給藥器排出之一次服用量之散劑之量變化,從而使形成於分配盤上之複數個散劑群中混合存在不同量之散劑群。 The method according to any one of claims 12 to 15, wherein the amount of the powder to be discharged from the applicator is changed, so that a plurality of powders are mixed in the plurality of powder groups formed on the distribution tray. group. 如請求項12至16中任一項之分藥方法,其使用複數個給藥器,且將自一個給藥器排出之散劑與自其他給藥器排出之散劑供給至分配盤之相同部位或接近之部位,將自一個給藥器排出之散劑與自其他給藥器排出之散劑設為一個混合散劑群,一併藉由刮出裝置刮出。 The method of dispensing according to any one of claims 12 to 16, wherein a plurality of dispensers are used, and the powder discharged from one dispenser is supplied to the same portion of the distribution tray as the powder discharged from the other dispensers or In the approaching portion, the powder discharged from one applicator and the powder discharged from other applicators are set as a mixed powder group, and scraped together by a scraping device. 如請求項17之分藥方法,其中自給藥器排出散劑並將散劑配置於分配盤之複數個部位,其後使分配盤反向旋轉,使與先用於排出之給藥器不同的給藥器相對地接近先配置之散劑附近,從而自已接近之給藥器排出散劑。 The method of dispensing according to claim 17, wherein the powder is discharged from the applicator and the powder is disposed in a plurality of portions of the dispensing tray, and thereafter the dispensing tray is rotated in the reverse direction to make a different administration from the dispenser previously used for discharging. The device is relatively close to the vicinity of the previously disposed powder, thereby discharging the powder from the applicator that is approaching. 如請求項17或18之分藥方法,其中個別地變更要被驅動之給藥器、與自給藥器排出之散劑之量,從而形成混合狀態不同之混合藥劑群。 The method according to claim 17 or 18, wherein the amount of the powder to be driven and the amount of the powder discharged from the dispenser is individually changed to form a mixed drug group having a different mixed state.
TW103141827A 2013-12-02 2014-12-02 Medicine dividing device and medicine dividing method TWI633041B (en)

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KR102215154B1 (en) 2021-02-10
WO2015083641A1 (en) 2015-06-11
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JPWO2015083641A1 (en) 2017-03-16
TWI633041B (en) 2018-08-21

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