201100175 六、發明說明： 【發明所屬之技術領域】 本發明係屬於奈米氣懸微粒產生器領域，特別是涉及一種可控制粒徑 之奈米氣懸微粒產生器。 【先前技術】 按’奈米科技（nanotechnology)已經被公認是新世代明星產業，但201100175 VI. Description of the Invention: [Technical Field] The present invention relates to the field of nano-airborne particle generators, and more particularly to a nano-airborne particle generator capable of controlling particle size. [Prior Art] According to 'nano technology, nanotechnology has been recognized as a new generation star industry, but
已經有流行病學研究報告指出：空氣中之奈米氣懸微粒（airb〇rae particle ’或稱之為氣膠（aer〇s〇1))，容易引發呼吸系統疾病或是心臟 血管疾病，所以有必要針對奈米微粒的防護與控制進行研究與探討。 習知之電嘴式霧化器是一鮮一粒徑分佈的奈米微粒產生方法，主要係 將液體由巾红細紐慢注人，並對毛細管與下游賴公分處之同轴環施 加約i〇kv之高電壓而使毛細管口處產生極高之電場，利賊d攝影機與榮 幕監視下，適度調整電壓使毛細管口處之液體形成泰樂錐（Tayi〇rc〇ne) 時’喷射出之液體柱直徑較毛細f之直徑更細，並因液體連接高電壓使液Epidemiological studies have pointed out that airborne sputum particles (airb〇rae particle ' or aerogel (aer〇s〇1)) are prone to respiratory diseases or cardiovascular diseases, so It is necessary to study and discuss the protection and control of nanoparticle. The conventional electric nozzle atomizer is a method for producing nano-particles with a particle size distribution, mainly by slowly injecting liquid from the towel red fine, and applying about i to the coaxial ring of the capillary and the downstream sub-base. The high voltage of 〇kv causes a very high electric field to be generated at the capillary mouth. Under the surveillance of the thief d camera and the glory screen, the voltage is adjusted moderately so that the liquid at the capillary mouth forms a Taile cone (Tayi〇rc〇ne) The diameter of the liquid column is thinner than the diameter of the capillary f, and the liquid is connected to the high voltage by the liquid.
體帶有極高淨簡，獅力導缝難破碎财形錄_數十至數百奈 米之液滴’ _再經過乾燥去除其中溶劑即成為奈米尺寸之微粒。 惟，上述電噴式霧化器其產生之微粒粒徑為—固定粒徑，益法翻 間内變化，财峨巾職罐_細™料各有不同 且到底不同之粒徑對人體或環境所造成之毒性為何乃有待研究，因此 =:】可產生徑—成為值得研究開發之課題。 徑 本案發明之内容，係為解決現行產生奈米 ’無法在短時間内變化之問題。其主要包括 尺寸之微粒粒徑為一固定粒 :電噴式霧化器、微量十字 201100175 型管接頭、毛細管、第—微量注射幫浦、第二微量注射幫浦及電腦； 利用電腦麟可程式控制之賴進料祕，使電喷式霧化器之液體進 料虞度可以在短時間内改變，令系統中霧化之液滴在溶劑揮發乾燥後，達 成隨意改變所產生的奈米微粒粒徑之目的。 【實施方式】 本發明係·液_化法產生奈錢雜粒，其係將液體分散或破碎 以產生氣驗滴，在乾燥空氣中這些液滴在極短__間揮發留下液體 〇中的溶質，該溶質即為本方法所要產生之氣雜粒。 — 假設氣膠產生器產生液滴之粒徑為dd，液滴中非揮發性成份之體積比 例為Fv ’乾燥後粒徑為dp，則液滴粒徑dd與乾燥後粒徑如之關係為. dP=dd(Fvr 本發明提供一種可控制粒徑之奈米氣懸微粒產生器，包括： 〇 電喷式霧化器（1); 微量十字型管接頭（2); 微粒混合腔（3); 毛細管（4); 第一微量注射幫浦（5 ); 第二微量注射幫浦（6); 高壓電源供應器（7); CCD攝影機（8 )暨監視螢幕（8 1); 201100175 電腦（9); 其中 所述微*十子型官接頭（2)係結合在該電喷式霧化器⑴； 所述電喷式霧化器（1)係結合在該微粒混合腔（3)-端； 所述微量十字型管接頭（2)，包括： 第一端（21)，係連接該第-微量注射幫浦（5); 第-端（2 2)，係連接該第二微量注射幫浦⑹； Ο 帛K23) ’係連接該毛細管⑷； 第2 4)係連接—導線（71)連接至該高壓電源供應器（7); 所述CCD攝如機（8 )暨監視螢幕（8丄），係用以觀察毛細管（4 ) 管口； 所述電腦（9)，其安裝有可同步驅動該第一微量注射幫浦（5)及第 二微量注射幫浦（6)進料之驅動程式； 本發明之操作程序，說明如下： 〇 將兩種不同濃度液體，分別由該第-微量注射幫浦（5)及第二微量 庄射幫浦（6 )，推進猶進人所述微量十字型f _⑵之第_端（2 1 )與第二端（2 2); 該微量十子型接頭（2)第三端（2 3)係連接至用以將混合液體霧 化之毛細管（4)，微量十字型管接頭（2)之第四端（2 4)係連接至 所述南壓電源供應器⑺，令液體導電以提供電喷式霧化所需之高電壓； 该電喷式霧化器⑴所產生之霧化液滴由空氣以及二氧化碳之混合 氣體攜’同4乾燥為粒子，並送至微粒混合腔⑶形成奈来微粒，其中 201100175 :乳化碳之作用為_其高介電常數以避免毛細管尖端與接地端之間產生 高壓放電，影響系統穩定； /所述可程式控制之第一微量注射幫浦⑶及第二微量注射幫浦⑷ 係藉由所述電腦（9)同步驅動，可以控制兩種不同濃度進料液體之進料 速率，使㊄合後液體濃度可以任意調整，當液體霧化後所產生之液滴具有 不同農度之溶質時，其中的溶劑揮發後所留下的微粒粒徑即隨之被改變， 達成在紐時間調整改變所產生奈米微粒粒徑之目的。 ° 而關於微量注射幫浦程式控制之操控測試，由於市售軟體並無法提供 同時驅動兩台以上微量注射幫浦之功能，為達到同步驅動兩台幫浦以控制 混合液濃度之絲，糊自賴㈣浦之料驅純體，驅絲體主控畫 面如第二圖所示，其操作步驟如下： 步驟-：在第-微量注射幫浦⑸及第二微量注射幫浦（6 )分別 準備不同濃度之進料液體並連接至所述微量十字型管接頭（2); 轉二：自電腦（9 )下載預先設定之液體注射速率程式至第一微量 〇 注射幫浦（5); 步驟二：自電腦（9)下載預先設定之液體注射速率程式至第二微量 注射幫浦（6); 步驟四：按【執行】鍵同時驅動該第—微量注射幫浦（5)及第一微 量注射幫浦（6)同步以程式控制進料率； 步驟五：調整所述高壓電源供應器⑺電壓，使職毛細管⑷ 出口之液體形成泰樂錐（Taylor cone)產生奈米微粒。 201100175 而基於上述之系統組成方式，本發明提供一種可達成以電喷式霧化法 產生奈米微粒之裝置，包括： 一電喷式霧化器（1 ); 量十字型管接頭（2) ’係結合於該電喷式霧化器（1)，包括： 第一端（2 1)，係連接第一液體注射管線（25); 第知（2 2)，係連接第二液體注射管線（μ); 第二端（2 3)，係連接一毛細管（a); 〇 帛四端(2 4)’係連接-導線(2 8)並連接至高壓電源； 是以，於該第-液體注射管線（2 5 )及第二液餘射管線（2 6 ) 分別注入不同濃度液體，經由控制兩種不同濃度液體之進料速率使混合 後液體濃度可雜意·，t霧化後職生之㈣財不同濃度之溶 質時，其中的溶劑揮發後所留下的微粒粒徑即隨之被改變，達成在短時間 調整改變所產生奈米微粒粒徑之目的。 #由上述結構，除提供液體混合與注射外，同時具備導電功能，以達 〇 成電嗔式霧化原理之作動。 以上所述者’僅為_本發明可能實施方式，惟料能以此限定本發 月實把之範圍’即凡依本發明申請專利||圍及創作說明書内容、圖式所作 之簡單的等效變化、修飾與置換，皆應屬於本發明專利涵蓋之範圍内。 【圖式簡單說明】 第一圖係本發明較佳實施例之結構組成示意圖 第一 A圖係本發明較佳實施例之微量十字型管接頭局部放大示意圖 第二圖係本發明較佳實施例之驅動軟體主控畫面示意圖 201100175 第三圖係本發明另一實施例示意圖 【主要元件符號說明】 1電喷式霧化器 2微量十字型管接頭 2 1第一端 2 2第二端 2 3第三端 0 24第四端 3微粒混合腔 4毛細管 5第一微量注射幫浦 6第二微量注射幫浦 7南壓電源供應益 71導線 81監視螢幕 8CCD攝影機 ❹ 9電腦The body has a very high net simplicity, and the lion's force guide is difficult to break the financial record _ tens to hundreds of nanometer droplets _ _ and then dried to remove the solvent into nanometer-sized particles. However, the particle size of the above-mentioned electrospray atomizer is - fixed particle size, the change in the profitable method, the different materials of the cans are different and the particle size is different for the human body or the environment. The toxicity caused is still to be studied, so =:] can produce diameters - becoming a subject worthy of research and development. The content of the invention in this case is to solve the problem that the current generation of nanometers cannot be changed in a short period of time. It mainly includes the size of the particle size of a fixed particle: EFI atomizer, micro cross 201100175 type pipe joint, capillary, first-micro injection pump, second micro-injection pump and computer; Depending on the feed, the liquid feed temperature of the electrospray atomizer can be changed in a short time, so that the atomized droplets in the system can be freely changed after the solvent is evaporated and dried. The purpose of the trail. [Embodiment] The present invention provides a liquid granule which disperses or crushes a liquid to produce a gas test droplet, and in a dry air, the droplets are volatilized in a very short period of time to leave a liquid sputum. The solute, which is the gas granule to be produced by the method. — Assuming that the particle size of the droplet produced by the gas gel generator is dd, and the volume ratio of the nonvolatile component in the droplet is Fv 'the particle size after drying is dp, the droplet size dd is related to the particle size after drying. dP=dd(Fvr The present invention provides a nanometer air suspension particle generator capable of controlling particle size, comprising: a krypton electrospray atomizer (1); a micro cross type pipe joint (2); a particle mixing chamber (3) Capillary (4); first microinjection pump (5); second microinjection pump (6); high voltage power supply (7); CCD camera (8) and surveillance screen (8 1); 201100175 computer (9); wherein the micro*10-type official joint (2) is combined with the electrospray atomizer (1); the electrospray atomizer (1) is coupled to the microparticle mixing chamber (3) The micro cross type pipe joint (2) comprises: a first end (21) connected to the first microinjection pump (5); a first end (2 2) connected to the second micro Injection pump (6); Ο 帛 K23) ' is connected to the capillary (4); 2 4) is the connection - the wire (71) is connected to the high voltage power supply (7); the CCD camera (8) and monitoring screen (8 ) for observing the capillary (4) nozzle; the computer (9) is equipped with a drive capable of synchronously driving the first micro-injection pump (5) and the second micro-injection pump (6) The operating procedure of the present invention is as follows: 〇 Two different concentrations of liquid are respectively transferred from the first-micro-injection pump (5) and the second micro-injection pump (6) to the tracer a first end (2 1 ) of the cross type f _(2) and a second end (2 2); the third end (23) of the micro-type sub-joint (2) is connected to a capillary tube for atomizing the mixed liquid ( 4) a fourth end (24) of the micro Phillips pipe joint (2) is connected to the south voltage power supply (7) to make the liquid conductive to provide a high voltage required for electrospray atomization; The atomized droplets generated by the atomizer (1) are dried by the mixed gas of air and carbon dioxide into particles, and sent to the particle mixing chamber (3) to form the nano particles, wherein 201100175: the role of the emulsified carbon is _ high Dielectric constant to avoid high voltage discharge between the capillary tip and the ground, affecting system stability; The first micro-injection pump (3) and the second micro-injection pump (4) controlled by the program are controlled by the computer (9) to control the feed rate of the two different concentrations of the feed liquid, so that the liquid concentration after the five-in-one It can be arbitrarily adjusted. When the liquid droplets produced by the atomization of the liquid have solute of different agricultural degrees, the particle size of the particles left after the solvent is volatilized is changed accordingly, and the nanometer produced by adjusting the change in the time is achieved. The purpose of particle size. ° Regarding the control test of the micro-injection pump program control, since the commercially available software cannot provide the function of driving more than two micro-injection pumps at the same time, in order to synchronously drive the two pumps to control the concentration of the mixed liquid, Lai (4) Puzhi material drive pure body, the main body of the drive body screen as shown in the second figure, the operation steps are as follows: Step-: Prepare the first-micro injection pump (5) and the second micro injection pump (6) respectively Different concentrations of feed liquid and connected to the micro cross-type pipe joint (2); Turn two: download the preset liquid injection rate program from the computer (9) to the first micro-injection pump (5); Step 2 : Download the preset liquid injection rate program from the computer (9) to the second micro injection pump (6); Step 4: Press the [Execute] button to drive the first-micro injection pump (5) and the first micro injection. The pump (6) synchronizes the program to control the feed rate; Step 5: Adjust the voltage of the high voltage power supply (7) so that the liquid at the outlet of the capillary (4) forms a Taylor cone to produce nano particles. 201100175 Based on the above system composition, the present invention provides a device for producing nano particles by electrospray atomization, comprising: an electrospray atomizer (1); a cross type pipe joint (2) The system is coupled to the electrospray atomizer (1), comprising: a first end (2 1) connected to the first liquid injection line (25); and a second (2 2) connected to the second liquid injection line (μ); the second end (23) is connected to a capillary (a); the four ends (24) are connected to the wire (28) and connected to the high voltage power supply; The liquid injection line (2 5 ) and the second liquid residual line (2 6 ) are respectively injected with different concentrations of liquid, and the liquid concentration after mixing can be mixed by controlling the feed rate of the two different concentrations of liquid. When the solute of different concentrations (4) is produced, the particle size of the particles remaining after the solvent is volatilized is changed, and the purpose of adjusting the particle size of the nanoparticles produced in a short time is achieved. # By the above structure, in addition to providing liquid mixing and injection, it also has a conductive function to achieve the action of the electric atomization atomization principle. The above description is only for the possible implementation of the present invention, but it is possible to limit the scope of the present invention to the extent that the patent application is based on the invention, the content of the creation manual, the simplicity of the drawing, etc. Modifications, modifications and substitutions are all within the scope of the invention. BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a schematic view showing the structure of a preferred embodiment of the present invention. FIG. 1 is a partially enlarged schematic view of a micro cross-shaped pipe joint according to a preferred embodiment of the present invention. 3D schematic diagram of another embodiment of the present invention [Description of main components] 1 electrospray atomizer 2 micro cross type pipe joint 2 1 first end 2 2 second end 2 3 Third end 0 24 fourth end 3 particle mixing chamber 4 capillary 5 first micro injection pump 6 second micro injection pump 7 south voltage power supply benefit 71 wire 81 monitor screen 8CCD camera ❹ 9 computer