TW201016194A - Device and method for estimating physical age index by measuring bioimpedance phase angle - Google Patents

Device and method for estimating physical age index by measuring bioimpedance phase angle Download PDF

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TW201016194A
TW201016194A TW97140366A TW97140366A TW201016194A TW 201016194 A TW201016194 A TW 201016194A TW 97140366 A TW97140366 A TW 97140366A TW 97140366 A TW97140366 A TW 97140366A TW 201016194 A TW201016194 A TW 201016194A
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phase angle
age
value
bioimpedance
phase
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TW97140366A
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Chinese (zh)
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TWI379664B (en
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Kun-Chang Hsieh
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Charder Electronic Co Ltd
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Abstract

A device and method for estimating physical age index by measuring bioimpedance phase angle, wherein the method comprises the steps of: inputting data including height, weight, age and sex or other data such as human race, physical activity, etc; selecting comparison standard modules: utilizing the computer to select the corresponding module to form a phase angle evaluation platform to acquire human body's physical data, including standard phase angle and standard bioimpedance phase angle estimation for evaluating reference physical age; measuring the contrast values of the human to be tested: using the bioimpedance technology to obtain the phase angle and the contrast body mass index, the contrast phase angle and the contrast body mass index generate a reference physical age, phase angle and the bioimpedance evaluation on the phase angle evaluating platform; contrasting the above three groups of values; integrating: integrating to obtain suggestions; and finally generating data sheet.

Description

201016194 六、發明說明: 【發明所屬之技術領域】 本七明係為-種人體量測生物阻抗相位角估測生理年 齡W之裝置與方法,尤指一種直接量測受測者之生物阻抗 相位角估測等人體資訊’其中,可直接經由原受測者之生物 阻抗相位角估測與相位肖配合於相位㈣估平台上產生各 員比對之對照值’以使受測者可有效快速的得知自己生理年 齡與實驗統計之標準值差距為何者。 【先前技術】 按生物阻抗法分析(Bi〇electrical丨即edance201016194 VI. Description of the Invention: [Technical Fields of the Invention] The present invention is a device and method for estimating the physiological age of a human body by measuring the bioimpedance phase angle, in particular, directly measuring the bioimpedance phase of the subject. Angle estimation and other human body information', in which the bioimpedance phase angle estimation and phase phase of the original subject can be directly matched to the phase (four) estimation platform to generate a comparison value of each member's 'to make the subject effective and fast I learned the difference between the standard age of my physiological age and the experimental statistics. [Prior Art] Analysis by bioimpedance method (Bi〇electrical丨 ie edance

Analysis)對於醫學電阻抗的研究最早始於19世紀末,生 物阻抗技術是利用生物組織與器官的電性特性(阻抗、介電 吊數4)及其變化提取人體生理、病理狀況相關的生物醫學 訊息的非侵入式檢測技術。通常是借助於皮膚表面的電極系 統向受測者發射一微小的交流電流或電壓,檢測相應的阻抗 及其變化情況,然後根據不同的應用目的,獲取相關的生理 與病理訊息。這種技術具非侵入、便宜、安全、無毒無宝、 操作簡單等特點,醫護人員與病人接易於接受,具有廣泛應 用前景。 生物電阻抗分析法綜合阻抗法與全身水量法,利用人體 能夠導電的性質給受測對象加入微小的電流,改變電流的頻 201016194 率使其在人體中的穿透深度發生變化’人體本身既有阻性又 有容性’所以不同頻率的電流穿透人體組織的深度不同^ “争 多的研究中,當電流頻率在較高的頻率上時電流可穿透人體 細胞膜,此時或在此之後繼續加大電流頻率所測量的阻於值 及為人體全身阻抗。當較低頻率時電流僅在細胞外通路中傳 播,這時測得的電阻值是人體細胞外阻抗,人體中的的&、 主要包括細胞内液與細胞外液。人體中的脂肪由於其含水量 ❹極小被認為是絕緣體,所以;當電流施加於人體後,將隨人 體内的水分遍及全身’作為人體内唯一的導電物質,人體的 電阻值將主要由人體中的水量決定。 關於生物阻抗相位角的研究應用上,01 iver曾針對健康 受測者、醫院病人與肝硬化的病人,針對其生物組抗相位角 差異進行研究比對。Lukaski對於懷孕婦女初、中、末與生 產過後時間之相位角進行研究。Brabose-Silva分別對於居 ❹住於都市832、1135名男女進行其年齡與相位角之關係研 究,Marra對於有厭食症的女性以相位角進行基礎代謝率 (Basal Metabolic Rate-BMR)預測關係研究。Guida 等人對 .於不同肥胖程度的老人,進行年齡、肥胖程度、相位角關係 之研究。除此之外關於相位角在人體測量臨床上的應用尚有 許多應研究,包含在HIV的觀測、肺癌(Lung cancer)、血 液透析(hemodialysis)、嚴重疾病(Critically iii)等等都 有其應用。 5 201016194 由以上的文獻回顧可得知,生物阻抗法之相位角應用, 大都均是針對某些特定族群或病患,在上述所提及的研究 中,可清楚歸納出相位角的減小,與健康狀況的惡化有著正 相關關係,接續隨著年齡的增加,有著隨之減少的趨勢,故 如以受測者相對相位角的增加與減少,為判斷受測者或者病 患的生理年齡狀態之重要指標。此外;生物阻抗法近年來多 用於人體組成成分的分析與推估,相位角是否與肥胖有何關 _ 係,在現有的研究與專利方面,應較為少見。 〇 生物阻抗法係將人體細胞浸於導電的細胞外液之中,而 細胞則由能選擇性通過某些離子的細胞膜包裹著導電的細 胞内液組成,細胞外液、細胞内液的電學性質接近於電阻, 而細胞膜則可能等效電容。因此人體的等效電路應當是若干 電阻、電容構成的串聯電路。為此,人們提出了多種的等效 電路,而應用最廣泛的三元件等效電路模型則如第1圖所 q 示;其中,圖中Ri、Re與C分別為細胞内液電阻、細胞外 液電阻與細胞膜電容,則其總阻抗可以表示為: Z = Re / / (ZC + Ri ) 生物阻抗分析的基本原理在於生物組織對外加電流長 具有不同導電作用,當在人體表面加一固定頻率的低電平電 流時,含水70%以上的肌肉組織是良好導體,而含水較少的 脂肪組織近似絕緣體,因此通過測出阻抗值,配合統計分 析,可以估算出身體組成成分,生物阻抗分析用於人體成分 6 201016194 分析是假設人體為一圓柱的幾何外型,生物組織中的水與電 解質的分佈均勻且恆定。根據C〇le-Cole理論,三元件 生物阻抗模型在複平面上的阻抗軌跡圖是在第四象限的一 段圓弧,如第2圖所示,這可解釋為等效電路中Ri與^串 聯的結果® 而目前對於大量健康人士進行之生物阻抗法相位角之 研究分別有Anja與Antonio等人,其中分別對國地區健康 ❹人士、非拉丁裔白人(non-Hispanic white)、非拉丁裔黑人 (non-Hispanic black)與墨西哥裔美國人(MexicanAnalysis) The study of medical electrical impedance began in the late 19th century. Bioimpedance technology is the biomedical information related to the extraction of human physiological and pathological conditions by utilizing the electrical properties of biological tissues and organs (impedance, dielectric number 4) and their changes. Non-intrusive detection technology. Usually, an electrode system on the surface of the skin is used to emit a small alternating current or voltage to the subject, detect the corresponding impedance and its changes, and then obtain relevant physiological and pathological information according to different application purposes. This technology is non-invasive, inexpensive, safe, non-toxic and unsecured, and simple to operate. It is easy for medical personnel to connect with patients and has broad application prospects. Bioelectrical impedance analysis method Comprehensive impedance method and whole body water quantity method, using the nature of the human body to conduct electricity, adding a small current to the object to be measured, changing the frequency of the current frequency of 201016194 to change the depth of penetration in the human body. Resistive and capacitive 'so different currents penetrate different depths of human tissue ^ "In the study of more than one, when the current frequency is at a higher frequency, the current can penetrate the human cell membrane, at this time or after Continue to increase the resistance measured by the current frequency and the whole body impedance. When the frequency is lower, the current only propagates in the extracellular pathway. At this time, the measured resistance value is the extracellular impedance of the human body, & It mainly includes intracellular fluid and extracellular fluid. The fat in human body is considered to be an insulator because its water content is extremely small. Therefore, when current is applied to the human body, it will follow the body's water throughout the body as the only conductive substance in the human body. The resistance value of the human body will be mainly determined by the amount of water in the human body. Regarding the research and application of the bioimpedance phase angle, 01 iver has been targeted at health. Subjects, hospital patients and patients with cirrhosis were compared for their biofilm anti-phase angle differences. Lukaski studied the phase angles of pregnant women at the beginning, middle and end of post-production time. Brabose-Silva Between 832 and 1135 men and women in urban areas, the relationship between age and phase angle was studied. Marra studied the relationship between Basal Metabolic Rate (BMR) and phase angle of women with anorexia. Guida et al. For the elderly with different degrees of obesity, the relationship between age, obesity and phase angle is studied. In addition to the clinical application of phase angle in anthropometry, there are still many studies to be included, including HIV observation, lung cancer (Lung cancer), Hemodialysis, Critically iii, etc. have their applications. 5 201016194 It can be seen from the above literature review that the phase angle application of bioimpedance method is mostly for certain ethnic groups or patients. In the above mentioned studies, it can be clearly concluded that the phase angle is reduced and has a positive correlation with the deterioration of health. As the age increases, there is a tendency to decrease. Therefore, if the relative phase angle of the subject is increased or decreased, it is an important indicator for judging the physiological age of the subject or the patient. In addition, the bioimpedance method has been in recent years. It is used for the analysis and estimation of human body components, and whether the phase angle is related to obesity. It should be rare in existing research and patents. 〇 Bioimpedance method immerses human cells in conductive extracellular fluid. Among them, the cells are composed of a cell membrane that selectively passes through certain ions, and the electrical properties of the extracellular fluid and the intracellular fluid are close to the electrical resistance, and the cell membrane may be equivalent to the capacitance. The equivalent circuit should be a series circuit composed of several resistors and capacitors. To this end, a variety of equivalent circuits have been proposed, and the most widely used three-element equivalent circuit model is shown in Figure 1, where Ri, Re, and C are intracellular liquid resistance and extracellular, respectively. The liquid resistance and cell membrane capacitance, the total impedance can be expressed as: Z = Re / / (ZC + Ri) The basic principle of bioimpedance analysis is that the biological tissue has different conductivity for the applied current, when a fixed frequency is added to the surface of the human body. At low level current, muscle tissue with more than 70% water is a good conductor, and fat tissue with less water is similar to insulator. Therefore, by measuring the impedance value and statistical analysis, body composition can be estimated, and bioimpedance analysis can be used. The analysis of human body composition 6 201016194 assumes that the human body is a cylindrical geometric shape, and the distribution of water and electrolyte in biological tissues is uniform and constant. According to the C〇le-Cole theory, the impedance trace diagram of the three-element bioimpedance model on the complex plane is a circular arc in the fourth quadrant. As shown in Fig. 2, this can be interpreted as the series connection of Ri and ^ in the equivalent circuit. Results® The current bioimpedance phase angle studies for a large number of healthy individuals include Anja and Antonio, among those in the country, non-Hispanic white, non-Hispanic whites. (non-Hispanic black) with Mexican Americans (Mexican

American)進行研究,使相位角研究的結果更為可信度提 高,則相同測試環境或者大量的的取樣數就變得非常重要, 惟目前對於此一研究之應用,仍屬少數。 【發明内容】 有鑑於斯,本案發明人乃經詳思細索,並積多年從 ❹種量測人體各項指數之產品與技術研發的經驗,終於開發出 -種人體量測生物时純肖_纽顿純之裝置與 本發明之目的在於提供一種人體量測生物阻抗相位角 估測生理年齡純之裝該方法,其主要賴相位 估平台以及其對應之相位角模組產生,經由該相位角評估平 台内之相位角㈣庫透過資料之建立,以選定對應之模組, 201016194 經簡單量測受測者的阻抗值與相位角,即可由模組中得到標 準之相位角、生物阻抗相位角估測與生理年齡等數值,並萨 比對整合後,即可獲得對照值、標準值以及參考值,並於: 議資料庫中取得相關建議之資料,而產生表單,而達到快速 量測以及簡單取得受測者目前生理狀態數值之目的者。、 本發明之目的係在於提供一種人體量測生物阻抗相位 角估測生理年齡指標之裝置與方法,而其敝之建立,主要 ❹係經過大量健康人士之進行過生物阻抗測量與資料庫建立 與統計研究,並將制量群时軌㈣f量純為區分等 級分舒㈣組’每個群組又分別以年齡分成次群纟且,詳細 的將各個群組與次群組的對應的生物電阻值 R(Resistance)、生物電抗值Xe(Reaeta職)其平均值血 差發表於該研究上,其_係經由辑綠釐清其關係y並 藉以為估測人體生理年齡之方法與機制。 ❿ 該方法之流程係包括: 輸入資料:輸入受測者的身高、體重與年齡或其他資 料’包括··人種膚色等資料; 選擇比對標準模組:_位_估平台之相位資料庫建 立對應模組,並產餘對之鮮值,包括:生物阻抗相 估測、相位角等數值; 量測受測者之比對數值:藉由針對於人體之四肢設置電 201016194 木、’座電極之發射與接收電極對透過單晶片、繼電器與程弋 控制,分別量測對應電阻抗值以及各項的對照值,其; 括.對照生理年齡、對照相位角以及對照生物阻抗相位角估 測’亚於該相位角評估平台中經由該對照值得出相對之 值; / 比對:於該相位角評估平台中進行比較,使對照值、參 考值與標準值等數值進行標準差分析; β 整合:將該標準差内容與建議資料庫内之資料比對整 產生表單:將前述建議與數值列表,受測者可輕易的由 表單得知該相位角、生物阻抗相位角估測與生理年齡與標準 值間之差異。 而前述之模組之建立流程係包括: 量測:針對受測者量測阻抗值、生物阻抗相位角估測以 ❹及相位角等數值,運用生物阻抗法進行量測,分別得到前述 各數值内容; 建構相位角評估平台:針對各受測者之年齡、身體狀 態、性別等條件建構出不同之標準模組,並形成以相位角、 年齡與生物阻抗相位角估測等條件予以統計分析形成相位 角評估平台以及相位角資料庫; 形成資料庫:於不同條件之標準模組部份,以累積受測 者之方式予以統計分析並統一標準化形成各模組之標準值 9 201016194 而予以記錄者。 以藉由該準確之標準值内容,包括:電阻值、相位角、 生物阻抗相位角估測以及年齡或其他資料等資料庫配合量 測出各受測者各部份數值,直接形成一實際年齡以及生理年 齡等各項數值之差異性,以強化受測者各部份之異常,而達 到提供與建議受測者各項生理數值以及應對補救之内容者。 【實施方式】 ❻ 有關本發明為達成上述目的,所採用之技術、手段及其 他之功效’兹舉一較佳可行實施例並配合圖式詳細說明如 : 后,相彳§本發明上述之目的、特徵及其他之優點,當可由之 :得一深入而具體之瞭解,惟本發明並非惟一之實施例,容此 說明之。 本發明之量測生物阻抗相位角估測生理年齡指標之裝 置與方法,係如第3、4與5圖所示,其中,本發明之量測 ®裝置10主要係具有—中央處理器U,中央處理器U主要連 接有-相位角資料庫12以及一建議資料庫13,以形成一相 位角評估平台20之主體,而該中央處理器u另連接一電源 14、-輸出裝置15、至少—輸人裝置16以及複數個輸入感 測器17 ’其中’中央處理器^即為一般的電腦之處理器, 相位角=貝料庫12係各標準模組之資料内容,包括:年齡、 姓別、體能狀況、人種、電阻值、生物阻抗相位角估測與相 201016194 位角;而建議資料庫13則為各項數值欠缺或超出時之因應 方法與内谷者;該電源14則可為一般之電池電源亦可交流 電電源者,該輸出裝置15係為顯示裝置,包括:電腦之螢 幕,輸入裝置16則可為鍵盤、或按鍵或觸控榮幕;輸入感 測器17則為接於受測者肢體上之電極對者。 該相位角評估平台20係為前述之相位角資料庫12架構 而成者,s亥相位角評估平台20係為一相位角0與受測者之 ❹年齡Age以及生物阻抗相位角估測BMI的關係形態之平台 者。 其中,該量測方法30之流程係包括: 輸入資料31 :受測者於前述之量測裝置1〇的輸入裝置 16上輸入本身之資料包括:受測者的身高、體重、年齡、姓 別與體能狀況等資料; 選擇比對標準模組32:藉由電腦判斷,以前述之受測者 參資料中,於相位角評估平台中之相位角資料庫12選取最 相近於受測者之標準模組,並取出該標準模組中之各項標準 值21,包括:相位角標準值、生物阻抗相位角估測標準值以 及電阻值標準值; 量測受測者之比對數值3 &amp;藉由針對於受測者人體之肢 體設置之量測裝置之各輸入感測器17,其可各別設於受 測者肢體之末端,量其電阻抗值、相位角以及生物阻抗相位 角估測,以形成對照值22 ’該對照值22係包括:電阻抗值、 11 201016194 =位角以及生物阻抗相位角估測等指數之數值;而輸入感測 态17係為一電極對結構,透過量測裝置ίο之單晶片中央處 理器11配合相位角資料庫12與建議資料庫13^成一相2 角評^平台2G,以使前述之各對照值22可經由該相位角評 估平台20之轉換形成前述各數值之參考值23。 比對34 :於該相位角評估平台2〇針對各標準值21、對 照值22以及參考值23進再行比對者; ❹,整合35:將前步驟中之值比對後,以各同質性之各數值 形,各別之標準差,進入建議資料庫13中進行資料之搜尋, 使符合各項標準差之建議内容得以取出; 產生表單36:將前述之各項數值以及經統計分析後由建 A貝料庫13中取得之建議内容共同列於同一表單上者; 受測者予以㈣,即可㈣數值上之差異以及建議得知 其生理年齡狀態。 ❹ 而就前述之相位角資料庫12結構予以有效的被建立, 該相位角資料庫12模組建立流程40係包括: 、量測41:針對受測者量測阻抗值、生物阻抗相位角估測 、相位㈣數值,運用生物阻抗法進行量測,分別得到前 述各數值内容,大量且不同的受測者進行量測; 建構相位角評估平台42 ··針對各受測者之年齡、身體狀 態、性別等條件建構出不同之標準模組,並形成以相位角、 年齡與生物阻抗相位角估測等條件予以統計分析形成相位 12 201016194 角評估平台20以及相位角資料庫12 ; 形成資料庫43:於不同條件之標準模組部份,以累積受 測者之方式予以統計分析並統一標準化形成各模組之標準 值而予以記錄者。 其中,該相位角評估平台20之模組化分析,係以統計 分析為之,若以各國人種為對象’其相位角Θ與受測者之年 齡Age以及生物阻抗相位角估測bmi的關係式如下: 義 male : 霸 (Θ) =Clmale+C2male X Age+C3male X BMI Female ·American) conducting research to make the results of the phase angle study more credible, the same test environment or a large number of samples becomes very important, but the application of this research is still a minority. [Inventive content] In view of this, the inventor of this case has carefully studied and accumulated many years of experience in product and technology research and development of human body indices, and finally developed a kind of human body measurement biological pure _Newton Pure Device and the purpose of the present invention is to provide a human body measurement bioimpedance phase angle estimation physiological age pure device, which is mainly based on the phase estimation platform and its corresponding phase angle module generation, through the phase The phase angle in the angle evaluation platform (4) is built by the data to select the corresponding module. 201016194 By simply measuring the impedance value and phase angle of the subject, the standard phase angle and bioimpedance phase can be obtained from the module. The angle is estimated and the physiological age and other values, and after the integration of Sabie, the control value, the standard value and the reference value can be obtained, and the relevant suggestions are obtained in the database, and the form is generated, and the rapid measurement is achieved. And the purpose of simply obtaining the current physiological state value of the subject. The object of the present invention is to provide a device and a method for estimating a physiological age index of a bioimpedance phase angle of a human body, and the establishment of the sputum is mainly carried out by a large number of healthy persons to perform bioimpedance measurement and database establishment and Statistical research, and the production group time track (four) f quantity purely divided into grades Shu (four) group 'each group is divided into subgroups by age, and the corresponding bioresistance of each group and subgroup in detail The value R (Resistance) and the bioreactor value Xe (Reaeta position) have the mean blood difference published in the study, and the method is based on the method and mechanism of estimating the physiological age of the human body.流程 The flow of the method includes: Input data: input the height, weight and age of the subject or other data 'including · human skin color; select the comparison standard module: _ bit _ evaluation platform phase database Establish the corresponding module, and the fresh value of the maturity, including: bio-impedance phase estimation, phase angle and other values; measure the measured value of the tester: by setting the electricity for the limbs of the human body 201016194 wood, 'seat The emitter and receiver electrodes of the electrode are controlled by a single chip, relay and process, and respectively measure the corresponding electrical impedance value and the control value of each, including: control physiological age, control phase angle and control bioimpedance phase angle estimation 'In the phase angle evaluation platform, the relative value is obtained through the comparison; / comparison: the comparison is performed in the phase angle evaluation platform, and the standard deviation analysis is performed on the values of the reference value, the reference value and the standard value; β integration : comparing the standard deviation content with the information in the suggested database to generate a form: the list of suggestions and values mentioned above, the subject can easily know the phase angle from the form, Bioimpedance phase angle estimation and the difference between physiological age and standard values. The above-mentioned module establishment process includes: Measurement: for the measured impedance value of the subject, the bioimpedance phase angle estimation, the value of the phase angle and the like, and the bioimpedance method is used for the measurement, and the foregoing values are respectively obtained. Content; Construct phase angle evaluation platform: Different standard modules are constructed for each subject's age, body state, gender, etc., and statistical analysis is carried out based on conditions such as phase angle, age and bioimpedance phase angle estimation. Phase angle evaluation platform and phase angle database; Forming a database: in the standard module part of different conditions, statistical analysis is performed by means of cumulative test subjects and standardized to form a standard value of each module 9 201016194 . By measuring the value of each accurate part of the standard value, including resistance value, phase angle, bioimpedance phase angle estimation, and age or other data, directly form an actual age. And the difference in the values of the physiological age, in order to strengthen the abnormalities of the various parts of the subject, and to achieve the physiological values of the testee and the content of the remedy. [ MODE FOR CARRYING OUT THE INVENTION </ RTI> </ RTI> </ RTI> </ RTI> </ RTI> </ RTI> </ RTI> </ RTI> </ RTI> </ RTI> </ RTI> <RTIgt; The features, advantages, and other advantages are apparent from the following detailed description of the invention. The apparatus and method for estimating the physiological age index of the bioimpedance phase angle of the present invention are as shown in Figures 3, 4 and 5, wherein the measurement device 10 of the present invention mainly has a central processing unit U, The central processing unit U is mainly connected with a phase angle database 12 and a suggestion database 13 to form a main body of the phase angle evaluation platform 20, and the central processing unit u is further connected to a power source 14, an output device 15, at least - The input device 16 and the plurality of input sensors 17 'where the central processor ^ is a general computer processor, the phase angle = the data content of each standard module of the 12-cell library, including: age, surname , physical fitness status, race type, resistance value, bioimpedance phase angle estimation and phase 201016194 locus; and recommended database 13 is the method of inaccurate or exceeding the value of the method and the inner valley; the power supply 14 can be Generally, the battery power source can also be an AC power source. The output device 15 is a display device, including: a computer screen, the input device 16 can be a keyboard, or a button or a touch screen; the input sensor 17 is connected to Subject The electrode pair on the limb. The phase angle evaluation platform 20 is constructed by the aforementioned phase angle database 12, and the phase angle evaluation platform 20 is a phase angle 0 and the age of the subject and the bioimpedance phase angle estimation BMI. The platform of the relationship form. The process of the measuring method 30 includes: input data 31: the subject inputs the data of the subject on the input device 16 of the measuring device 1〇, including: height, weight, age, and surname of the subject Data such as physical condition; selection standard module 32: by computer judgment, in the aforementioned subject data, the phase angle database 12 in the phase angle evaluation platform selects the standard that is closest to the subject Module, and take out the standard value 21 in the standard module, including: phase angle standard value, bioimpedance phase angle estimation standard value and resistance value standard value; measuring the comparison value of the subject 3 &amp; Each of the input sensors 17 of the measuring device provided for the limbs of the human body of the subject can be respectively disposed at the end of the limb of the subject, and the electrical impedance value, the phase angle, and the phase angle of the bioimpedance are estimated. Measured to form a control value 22 'The control value 22 includes: an electrical impedance value, an index of 11 201016194 = position angle and a bioimpedance phase angle estimation; and the input sensing state 17 is an electrode pair structure, through Measuring device ίο The single-chip central processing unit 11 cooperates with the phase angle database 12 and the suggested database 13 to form a phase 2 evaluation platform 2G, so that the aforementioned comparison values 22 can be converted by the phase angle evaluation platform 20 to form the aforementioned numerical values. The reference value is 23. Alignment 34: The phase angle evaluation platform 2 再 re-aligns the standard value 21, the control value 22, and the reference value 23; ❹, integration 35: compares the values in the previous steps, and then homogeneity Each numerical value of the sex, the standard deviation of each, enters the recommendation database 13 to search for the data, so that the recommended content that meets the standard deviation can be taken out; Generate Form 36: After the above numerical values and after statistical analysis The suggestions obtained from the construction of the A-Bag library 13 are listed on the same form; the subjects are given (4), and the difference between the values of (4) and the recommended physiological age. ❹ The structure of the phase angle database 12 is effectively established. The phase angle database 12 module establishment process 40 includes: Measurement 41: Measuring impedance value and bioimpedance phase angle estimation for the subject The measured and phase (four) values are measured by the bioimpedance method, and the above numerical contents are respectively obtained, and a large number of different subjects are measured. The phase angle evaluation platform 42 is constructed. · For each subject's age and body state Conditions such as gender and gender construct different standard modules, and form statistical analysis by phase angle, age and bioimpedance phase angle estimation to form phase 12 201016194 angle evaluation platform 20 and phase angle database 12; form database 43 : In the standard module part of different conditions, statistical analysis is carried out in the form of cumulative test subjects and standardized to form the standard values of each module and recorded. The modular analysis of the phase angle evaluation platform 20 is based on statistical analysis, and the relationship between the phase angle Θ and the age of the subject Age and the bioimpedance phase angle estimation bmi is taken for each ethnic group. The formula is as follows: 义male: 霸(Θ) =Clmale+C2male X Age+C3male X BMI Female ·

(θ) = ClFemale+C2Female x Age +C3Femalex BMI /、中,C1-C6為統§·]*分析所得係數,故前述之對照值22 可兩兩代入各標準模組中之關係式中,分別得出不同之參考 值23,經由對照值22與參考值23間之差異以及對照值22 ❹與“準值21之鮮差,可得知,受測者之實際狀況與標準 值或參考值相差之數值為何?,受測者即可經由該一相位角 =估平台20各關係式帽得各項錄,關至建議資料庫 選取對應之内容,而可由表單中輸出觀之者。 其中’藉由對照值22與標準值21間之差異可知,受測 者身體狀況與賴組中之標準相差之量,亦可由對照值U 與參考值23之比對而得知各項數值可能變異之方向者。 综上所述’本案發明所揭露人體量測生物阻抗相位角估 13 201016194 測生理年齡指標之裝置與方法,特殊之設計已『具有產業之 可利用性』應已毋庸置疑,除此之外,在本案創作所揭露出 的技術特徵,於申請之前並未曾見於諸刊物,亦未曾被公開 使用,加之又具有如上所述功效增進之事實,是故,本發明 的『新穎性』及『進步性』均符合專利法規定,爰依法提出 創作專利之申請,祈請惠予審查並早日賜准專利,實感德便。 【圖式簡單說明】 ❹ 第1圖係傳統生物阻抗法分析示意圖。 第2圖係傳統相位角示意圖。 第3圖係本發明量測裝置示意圖。 第4圖係本發明量測方法示意圖。 第5圖係本發相位角資料庫建制流程示意圖。 【主要元件符號說明】 量測裝置10 中央處理器11 建議資料庫13 電源14 輸入裝置16 輸入感測器17 相位角評估平台20 對照值22 參考值23 量測方法30 輸入資料31選擇比對標準模組32 量測受測者之比對數值33 相位角資料庫12 輸出裝置15 標準值21 比對34 14 201016194 整合35 產生表單36 模組建立流程40 量測41 建構相位角評估平台42 形成資料庫43(θ) = ClFemale+C2Female x Age +C3Femalex BMI /, medium, C1-C6 is the §·]* analysis of the obtained coefficients, so the above-mentioned comparison value 22 can be substituted into the relationship between the standard modules, respectively A different reference value 23 is obtained, and the difference between the control value 22 and the reference value 23 and the difference between the control value 22 ❹ and the “precision value 21” indicate that the actual condition of the subject differs from the standard value or the reference value. What is the value? The testee can use the phase angle to estimate the relationship of the platform 20, and close the recommended database to select the corresponding content, and the output can be viewed from the form. From the difference between the control value 22 and the standard value 21, it can be known that the difference between the physical condition of the subject and the standard in the Lai group can also be obtained by comparing the comparison value U with the reference value 23 to know the direction of possible variation of each value. In summary, the apparatus and method for measuring the physiological impedance age of the human body measured bioimpedance phase angle estimation 13 201016194, the special design has been "having the availability of the industry" should be undoubted, in addition to this In addition, revealed in the case of the case The technical features have not been seen in publications before the application, nor have they been used publicly. In addition, the facts of the above-mentioned effects are enhanced. Therefore, the "novelty" and "progressiveness" of the present invention are in compliance with the provisions of the Patent Law.爰Proposed an application for the creation of a patent in accordance with the law, praying for review and early granting of patents, and real feelings. [Simplified illustration] ❹ Figure 1 is a schematic diagram of traditional bioimpedance analysis. Figure 2 is a schematic diagram of traditional phase angle Figure 3 is a schematic diagram of the measuring device of the present invention. Figure 4 is a schematic diagram of the measuring method of the present invention. Figure 5 is a schematic diagram of the process of constructing the phase angle database of the present invention. [Description of main component symbols] Measuring device 10 Central processing unit 11 Recommended database 13 Power supply 14 Input device 16 Input sensor 17 Phase angle evaluation platform 20 Control value 22 Reference value 23 Measurement method 30 Input data 31 Select comparison standard module 32 Measure the comparison value of the testee 33 Phase Angle Library 12 Output Device 15 Standard Value 21 Comparison 34 14 201016194 Integration 35 Generation Form 36 Module Creation Process 40 Measurement 41 Construction Phase Angle Evaluation Platform 42 Into a database 43

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Claims (1)

201016194 七、申清專利範圍: 1種人體量測生物阻抗相位角估測生理年齡指標之 裝置,其中,該量測裝置係包括·· 一中央處理器’該巾央處理輯接有—相㈣資料庫以 及一建議資料庫,以形成—相位脚估平台之主體,而該中 央處理器另連接—電源、—輸出裝置、至少—輸人裝置以及 複數個輸入感測器; 該相位角4估平台係為-相位角Θ與受測者之年齡Age 以及身體質量指數BMI的關係平台; 該相位角資料庫係各標準模組之資料内容,包括.年 齡、姓別、體能狀況、人種、國別、電阻值、生物阻抗相位 角估測與相位角; 該建議資料庫則為各項數值欠缺或超出時之因應方法 與内容者; ❹ 錄人感測11則為接於受測者肢體上之電極對者。 2 ·如申請專利範固第1項所賴人體量測生物阻抗相 位角估測生理年齡指標&gt; 4之裝置’其中’該中央處理器 腦之處理n,相位角心平台 則為-電池電源或交流電㈣者.讀屮關’錢源 置,係包括:電腦之鸯幕電:者二,置係為顯示裝 發幕者。 鱗’輪入裝置則為鍵盤或按鍵或觸控 16 201016194 3 一種人體量測生物阻抗相仇角估測生理年齡指標之 方法,其中,該量測方法之流程係包括: 輸入資料:受測者於-量測裝置的輪人裝置上輸入 之資料包括:受測者的身高、體重、年齡、姓別與體能狀況 等資料; 選擇比對標準模組:藉由電腦_,以前述之受測者次 料中’於-相位角評估平台中之相位角資料庫選取最相近二 ❺ 受測者之標準模組’絲㈣標準模纟种之各項標準值 括:相位角標準值、生物阻抗相位角估測標準值以及電阻= 標準值; Ο &gt;量啦測者之比對數值:藉由針對於受測者人體之肢體 设置之該ϊ測裝置之各輪人感測器’該輪人感測器其可各別 設於受測者賴之末端’量其電阻抗值、相位角以及生物阻 抗相位角估測,以形成對照值,崎照值係包括:電阻抗抗 =、相位角以及生物阻抗相位角估測等指數之數值;而輸入 感測器係為-電極對結構,透過該量測裝置之片中央處理器 配合相位角資料庫與建議資料庫形成—相位脚估平二,^ 恢轉換形成前 參考該相位㈣料台騎各標準值、對照值以及 麥考值進再行比對者; 整合:將前步财之值崎後,“建議:#料庫中進行 17 201016194 〆 資料之搜尋,使符合各項建議内容得以取出; 產生表單:將前述之各.纽及經域議資料庫中取 得之建議内容共同列於同一表單上者; 受測者予以取用,即可由該數值上之差異以及建議得知 其生理年齡狀態。 4·-種人體量测生物阻抗相位角估測生理年齡指標之 方法’其中,該相位角資料庫之模_立流程係包括: ❹ 量測:針對相者量測阻抗值、生物阻抗相㈣估測以 及相位料數值,獅生物阻抗法進行量測,分別得到前述 各數值内谷,大量且不同的受測者進行量測; 建構相位角評估平台:針對各受測者之年齡、身體狀 態、性別等條件建構出不同之標準模組,並形成 年齡與生物阻抗相位角估測等條件予以統計分析形成相位 角評估平台以及相位角資料庫; 形成資料庫··料同條件之縣—部份,以累積受測 者之方式予以統計分析並統-標準化形成各模組之 而予以記錄者。 5 ·如申請專利範圍第4項所述的人體量啦物阻抗相 位角估測生理年齡指標之裝置,其中,該相位角評估平△之 模組化分析,係以統計分析為之,料—相㈣㈣受;者 之年齡Age以及生物阻抗相位角估測MI_係如下: male : 18 201016194 (&lt;9) =Clmale+C2male x Age+C3male x BMI Female · (Θ) = ClFemale+C2Feraale x Age +C3Femalex BMI201016194 VII. Shenqing patent scope: A device for measuring the physiological impedance age of the bioimpedance phase angle, wherein the measuring device includes a central processing unit. a database and a suggested database to form a body of the phase estimation platform, wherein the central processor is further connected to a power source, an output device, at least an input device, and a plurality of input sensors; The platform is a platform for the relationship between the phase angle Θ and the age of the subject and the body mass index BMI; the phase angle database is the data content of each standard module, including age, surname, physical condition, ethnicity, Country, resistance value, bioimpedance phase angle estimation and phase angle; The suggested database is the method and content for the lack or excess of each value; ❹ Recording sensor 11 is connected to the subject's limb The electrode pair on the top. 2 · If the patent application is based on the first measure of biometric impedance phase angle estimation physiological age indicator &gt; 4 device 'where 'the central processor brain processing n, phase angle center platform is - battery power Or AC (4). Read Shaoguan 'Qianyuan, including: the curtain of the computer: the second, the system is the display device. The scale 'wheeling device is a keyboard or button or touch 16 201016194 3 A method for measuring the physiological age index of the human body impedance bio-energy angle, wherein the measurement method includes: input data: the subject The information input on the wheel device of the measuring device includes: height, weight, age, surname and physical condition of the subject; selection of the standard module: by computer _, the aforementioned test In the secondary material, the phase angle database in the 'phase-phase angle evaluation platform selects the closest two. The standard module of the tester's standard standard of silk (four) standard model includes: phase angle standard value, bioimpedance The phase angle estimation standard value and the resistance = standard value; Ο &gt; the ratio of the measured value: the wheel sensor of the measuring device set by the limb of the human body of the subject' The human sensor can be set at the end of the subject to measure its electrical impedance value, phase angle and bioimpedance phase angle to form a control value, and the amplitude value includes: electrical impedance resistance, phase Angle and bioimpedance The position angle is estimated as the value of the index; and the input sensor is an electrode-to-electrode structure, and the central processor of the measuring device is formed by the phase angle data base and the suggested data base - the phase foot is estimated to be flat, and the recovery is Before the conversion is formed, refer to the phase (4). The standard value of the table, the comparison value, and the value of the Macaw are re-matched. Integration: After the value of the previous step, "Recommendation: #料库17 171616194 〆 Searching so that the content of each recommendation can be taken out; generating a form: the recommended content obtained in each of the aforementioned New Zealand and the domain research database is listed on the same form; Numerical differences and suggestions for the physiological age status. 4·-A method for measuring the bioimpedance phase angle to estimate the physiological age indicator', wherein the model of the phase angle database includes: ❹ Measurement : For the phase measurement impedance value, the bio-impedance phase (four) estimation and the phase material value, the lion bio-impedance method is used to measure the respective values, and a large number of different subjects are performed. Constructing a phase angle evaluation platform: constructing different standard modules for each subject's age, body state, gender, etc., and forming conditions such as age and bioimpedance phase angle estimation for statistical analysis to form a phase angle evaluation platform And the phase angle database; the county-parts that form the database and the same conditions, are statistically analyzed in the manner of accumulating the subjects, and are standardized-formed to form each module and recorded. 5 · If the patent application scope The device for estimating the physiological age index of the human body mass impedance phase angle according to item 4, wherein the modular analysis of the phase angle evaluation flat △ is performed by statistical analysis, and the material-phase (four) (four) is received; The Age Age and Bioimpedance Phase Angle Estimate MI_ are as follows: male : 18 201016194 (&lt;9) =Clmale+C2male x Age+C3male x BMI Female · (Θ) = ClFemale+C2Feraale x Age +C3Femalex BMI 1919
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