200810742 九、發明說明： 【發明所屬之技術領域】 本發明係有關於正確扣搭於小藥瓶（vial)上之液體藥物移 轉裝置。 【先前技術】 美迪摩公司（Medimop Medical Projects Ltd·，Ra，anana、 以色列）供應液體藥物移轉裝置，係與裝有液體或粉末藥物内容 物及具一個用傳統橡皮塞塞住開口之小藥瓶一起使用。小藥瓶典 型使用的是13/14毫米和20毫米標準尺寸，通常裝有昂責藥物、。 液體藥物移轉裝置包括：主要是附單腔穿刺針（single ium如 puncturing spikes)的小藥瓶應接器（vial、附二 重腔穿刺針的通氣小藥瓶應接器（vented vial adaptos)、登 載於PCT國際出版品W096/291丨3之液體控制裝置、Zinger等人之 登載於美國專利案號6, 558, 365的MIX2VIA1；液體控制裝置、登載 於pct國際出版品w_5/105014的線上_虹液體控制^ 置、及其同_。㈣熱㈣裝践供專紐用者使用，並且 也供居家使用者’如年輕者、視力不全者、體弱者和類似者，為 了自我給舉目的而在家使用。 、 液體藥物移轉裝置包括：一個塑谬的造型小藥瓶應接器 (adapter) ’附有一個大體上圓筒形外緣（制⑴，用於自由 伸縮滑動錢受其間的—個小藥瓶開口 ；—個—體成型中空穿刺 5 200810742 針，用來穿鮮藥瓶眺塞，及至少有—個流體孔隙向著穿刺針 (Puncturing spike)尖端，用來通到小藥瓶的内部；以及至少 一個連接埠（access 使流體流至穿刺針。外緣—般包細 或六個可動元件（flex members)，其中包含至少兩個不相鄰的 附有至少部分圓周伸展向内突出的小藥瓶持留支伽架（咖 mention ribs)的小藥瓶持留可動元件（㈣时贈-— _berS) ’用來搭扣到小藥瓶的開口上達到小藥瓶持留的目的。 小樂瓶持留可動元件之設計，係例如小胸瓦應接器被扣搭上以 後’就不會從-個醫藥小藥瓶脫落，以確保消毒無菌目的。不作 為小藥瓶持留目的之可動元件具有平滑的内表面，用來支撐小藥 槪開口維持赫域目的。這類小無g可動元件（vial 呂她山加咖flex議⑽）—般都是與它們的配對小藥瓶持 留可動元件有相同長度，但也可能麵—些，例如等人 在美國專利申請公報案號2()()3/咖847所顯示者。 液體樂物移轉裝置和小藥瓶若沒有排列緊密，將導致穿刺困 難，並且在某些例子#巾，糾、藥瓶應難之穿刺針尖端會埋入 •I市瓶的瓶基中’因此阻絕了和小藥瓶内部液體的流通。在這樣 的例子中，儘管小藥瓶含有—個全劑錢物，仍然必須廢棄。長 久以來，不正確扣搭小藥瓶應接關小藥瓶上，至少部分造成以 下所“述的醫療小藥瓶的設計問題點。液麵物移轉裝置的專業 使用者通常都會注意這個設計上的問題特色，但是因為趕時間或 200810742 其他類似情形，仍有可能把小藥瓶應接器不正確扣搭到小藥瓶 ^液體_移_置的居家使用者通常沒有認知這類設計上問 遞’耻儘管已經盡力了，還是更容易把小藥瓶應接器不正確扣 才合到小樂瓶上。 【發明内容】 =發明係有關於液體藥物移轉裝置，該裝置包括—個小藥瓶 應接器，係為確保與小藥瓶内部驗黯躺設計作為正確扣搭 在-個醫療用小藥瓶上之安全設計。小藥瓶應接器包含至少兩個 不相鄰的小藥瓶持留可動科，絲正確扣搭在小藥瓶開口上以 確保小藥麟留目的，以及至少兩個不婦的小藥瓶引導可動元 件（vial guidance flex members)，長度較長於其對應小藥瓶 持4可動元件彳、藥瓶應接器扣搭在小藥瓶上以前，用來引導該 小樂瓶應接H。小藥瓶料可動元件之設計就是它們可協助使用 者將-個液體藥物遞送裝置之穿刺針和—個小藥瓶正確地同轴排 列，在前者之穿刺針接觸後者之瓶塞以前就已排成一列。再者， 小藥瓶引導可動元件亦較易讓使用者更謹慎地達到扣搭過程，因 此’對於正確扣搭有相當的幫助。 【實施方式】 圖一和圖二顯示一個用來正確扣搭在一個傳統藥用小藥瓶Η 上之安全設計的液體藥物移轉裝置1〇，小藥瓶u有一個縱向軸 12、一個瓶身部分13包含一種液體藥物14、一個小藥瓶開口 16、 7 200810742 及:個介於瓶身13和開口 16之間的窄頸17。開口 16通常是由橡 皮基18塞住，橡皮塞18有一個環狀頭部19和一個向下延伸管狀 部2卜該管狀部具有—個隱藏的鑽孔（Mind匕⑽）a，其有一 個與縱轴12橫切之橫切面A1。小藥瓶11係被具有圓緣（恤）24 的一個紹II (aluminum band) 23所密封，該圓緣24有外㈣、 且有沿轴周圍表面26、並接觸橡皮塞18之一個***的中央區域 27。橡皮塞之中央_ 27有—倾_ 12橫切之橫切面μ，盆 :=A:，_A2>A1之設計特徵長導致小 ^體:岐有排成-列，因為朗者有錯誤印象，以為他們在 牙刺日守有一個比較實際為大的目標範圍。 ^體藥物移轉裝置1G包括—個塑膠塑模的小藥瓶應接器 的一個縱軸31、和—個用來接受注射筒（未顯示） ^30 Cf6maleLUer~-) 二了-體-。小藥瓶應接器3〇包括一個與咖 頁土 (top wa 11) 33，和一個杏所^同々斤 地而H声 個只貝上固_外緣34，能自由伸縮 之小藥瓶開°16。外緣34包括三個不相鄰的順 :件37,爾•有雜_ == 30包括一個一體成形中空的 市瓶應接為 做液體交流，_38具有妾= 體孔隙（flow aperture) 4卜 、上有-個液 200810742 -小樂麟留可動树36有内表面36A並向外逐漸變細到可動 兀件頂端編而且有一個内徑咖，及一個與頂壁％間的長度 ^。内部表面編裝備了圓周伸展向内突出的小藥瓶持留支樓肋又 (ial retention ribs) 36C ’用來扣搭到小藥瓶開口 16上， 以逹^藥瓶持留目的。當液體藥物移轉裝置1〇扣搭在—個小藥瓶 11上時/’穿刺針尖端39向下伸展輕輕通過小藥瓶持留支撐肋架 “C使知牙刺針的液體孔隙41停駐在小藥瓶隱藏鑽孔&中。小 樂瓶引導可動元件37有平直的内表面37A並延伸至可動元件頂端 而且有個内從D3,而D2>D3>D1，及一個與頂壁33間的長度 L2 j〉U。可動70件頂端37β向下伸展超過可動元件頂端36B， 因此則者在穿刺針尖端39接觸到小藥瓶瓶塞Μ以前就接觸一個 箍的圓緣24，用來正確㈣導液體藥物遞送裝龍與小藥瓶u 排成同心軸排列。 液體藥物遞送裝置10之安全設計的正確扣搭在一個小藥瓶 11场撕於圖三Α至三Ε。使用者往往騎體祕遞送裝置1〇 和小樂瓶11不正確地排列，如偏離液體藥物遞送裝置的中心 (圖三Α)或以一個角度靠向小藥瓶u (圖三Β)。小藥瓶引導可 動元件37協助使用者讓液體藥物遞送襄置1〇和小藥瓶u同軸排 在穿刺針尖端39接觸小藥瓶瓶塞18以前，使可動元件頂端 B冋時接觸箍的圓緣24 (參看圖三C)。液體藥物遞送裝置i〇 開始向小藥瓶u下_，使小引導可動元件37 _呂箍的 9 200810742 錢心Γ㈣娜料，糊物39接觸小藥瓶瓶 二=樂瓶嫩伽鐵下之咖接觸箱的圓 =吏u«丨導可動元件37滑的賴表面 的隱藏鑽孔22㈣H上，液體孔隙41就位在瓶塞 (參看圖三^ 氏連接器％有效地液體交流 =顯示-個液體藥物移難置5Q ’和液體藥物移轉裝置1〇 =51、、°構她’侧辦峨恤含-個小藥瓶應 件。心销H有兩财相_财⑽小藥雜留可動元 口兩個不相鄰同軸方向的小藥瓶引導可動元件37。 接哭Γ顯示一個咖π液體控制裝置6〇附一個類似小藥瓶應 /的可分離小藥瓶應鮮61，作騎全設計正確扣搭在一個 藥用小藥瓶上。 3d本&⑽藉著有限數目的具體模式例加以描纟會說明，但 疋1所週知’凡是從本發明所作之許多變化、修改、及其他應用 仍屬於以下申請翻_之領域。 【圖式簡單說明】 為了瞭解本發明並觀察其實際之操作，藉由無侷限之實施 割田述理想的具體模式例，關於各圖其巾相同部位係標示同 樣數字，其中： 200810742 上之安全設計 圖-係-條_师轉裝置之第—理想具職式例轉圖式概 觀，具有-個小藥瓶應接器作為正確扣搭在—個藥用小藥瓶 圖二係-個液體雜移轉裝置及圖_之_小藥瓶沿著Μ線 縱斷面。 之 圖三A係-個縱斷面顯示-個液體藥物移轉裝置對於藥用小藥瓶 偏離中心點。 μ 藥用小藥瓶 圖三B係-個縱斷面顯示-個液體藥物移轉|置對於藥用， 有角度。 ” 圖三C係-個液體藥物移轉裝置與_小藥瓶同軸排列而安全扣 搭其上的縱斷面。 圖二D係一個液體藥物移轉裝置輕撒 1彳桃向關小藥瓶壓下的縱斷 圖三E係-個液體祕移轉裝置扣搭在藥則、藥瓶上並與小藥瓶 内部有流體交流的縱斷面。 圖四係i液縣物移轉裝置之第二理想具體模式例崎圖式概 硯，具有-個通氣小藥瓶應接器附正確扣搭在—個藥用小藥 瓶上之安全設計；以及 圖五係―個Μ赋f液體控繼_物式概觀，具有一個小藥 _接器附正確扣搭在-個_倾瓶上之安全設計。 200810742 【主要元件符號說明】 10···· ••液體藥物移轉裝置 11···· ••小藥瓶 12···· ••縱向軸 13···· ••瓶身 14···· ••液體藥物 16···· ••開口 17…· ••窄頸 18 ·. •…橡皮基 19…· ••環狀頭部 21···· ••管狀部 22···· ••鑽孔 23…· ••紹猶 24…· ••圓緣 26…· ••周圍表面 27…· ••中央區域 30···· ••小藥瓶應接器 31···· ••縱軸 32···· ••内凹劉氏連接器 33…· ••頂壁 34…· ••外緣 36…· ••可動元件 36A" 36B·· …·可動元件頂端 36C·· …·肋架 37…. ••可動元件 37A·· 37B·· …·頂端 38…. ••穿刺針 39…. …尖端 41···· …孔隙 50…. …液體藥物移轉裝置 5l···. …小藥瓶應接器 60…· …液體控制裝置 6l···· …小藥瓶應接器 Al···. …檢切面 A2…· …棱切面 D1-- …外徑 Ll···. …長度 L2·… …長度 12200810742 IX. DESCRIPTION OF THE INVENTION: TECHNICAL FIELD OF THE INVENTION The present invention relates to a liquid drug transfer device that is properly attached to a vial. [Prior Art] Medimoop Medical Projects Ltd. (Ra, anana, Israel) supplies liquid drug transfer devices that are filled with liquid or powdered drug contents and have a small opening with a conventional rubber stopper. Use the vials together. Small vials are typically used in standard sizes of 13/14 mm and 20 mm and are usually filled with medications. The liquid medicine transfer device comprises: a small vial adapter (single vial accommodating needles) (vial, a vented vial adaptos with a double-lumen puncture needle) Liquid control device of PCT International Publication No. W096/291丨3, MIX2VIA1 of Zinger et al., U.S. Patent No. 6,558,365; liquid control device, published on the line of pct international publication w_5/105014 _ rainbow liquid control ^ and its same _. (d) heat (four) installed for the purpose of the use of special users, but also for home users 'such as young, visually impaired, infirm and similar, for self-giving purposes And at home, the liquid drug transfer device includes: a plastic styling small vial adapter (attached) with a generally cylindrical outer edge (made (1) for freely telescopic sliding money received by - a small vial opening; - a body-formed hollow puncture 5 200810742 needle, used to wear a bottle of fresh medicine, and at least a fluid pore toward the tip of the puncturing spike, used to access the vial Internal; At least one connection port (access causes fluid to flow to the puncture needle. The outer edge is generally thin or six flex members, including at least two non-adjacent small drugs with at least partial circumferential extension inwardly protruding The vial holding the movable ribs holds the movable element ((4) when it is given - _berS). It is used to fasten the opening of the vial to the small vial for the purpose of holding the small vial. The design of the component, for example, after the small chest tile connector is buckled, will not fall off from a pharmaceutical vial to ensure sterile sterilization. The movable component that is not used as a small vial has a smooth inner surface. It is used to support the opening of the small drug to maintain the Hetian domain. These small g-free movable components (vial Lushanshan plus coffee flex (10)) are generally the same length as their paired vials retaining movable elements, but It is also possible to do so, for example, as shown in U.S. Patent Application Publication No. 2()() 3/Caf 847. Liquid music transfer devices and vials are not closely arranged, which may result in difficulty in puncture, and In some examples #巾, Correction, the bottle should be difficult to puncture the tip of the needle will be buried in the bottle base of the 'I city bottle', thus blocking the flow of liquid inside the small vial. In this case, although the small vial contains a full dose of money Things must still be discarded. For a long time, improperly buckled small vials should be connected to small vials, at least in part to cause the design problems of the medical vials described below. Professional use of liquid level transfer devices Usually pay attention to the design features of the problem, but because of the rushing time or other similar situations in 200810742, it is still possible to improperly buckle the vial adapter to the small vial ^liquid_shift_home users usually I don't know how to design such a design. Although I have tried my best, it is still easier to put the small medicine bottle adapter incorrectly and put it on the small bottle. SUMMARY OF THE INVENTION The invention relates to a liquid medicine transfer device, which comprises a small vial adapter, which is to ensure that the internal design of the small vial is properly buckled in a small medical drug. The safety design on the bottle. The vial adapter contains at least two small vials that are not adjacent to each other. The silk is properly fastened to the opening of the vial to ensure that the small drug is reserved, and at least two small vials are guided. The vial guidance flex members are longer than the corresponding small vial holding 4 movable components, and the vial adapter is used to guide the small bottle to be connected to H. The design of the movable components of the small vial is that they can assist the user to correctly arrange the puncture needle of the liquid drug delivery device and the small vial correctly, before the puncture needle of the former contacts the stopper of the latter. In a column. Furthermore, it is easier for the vial to guide the movable element to allow the user to more cautiously reach the buckle process, so that it is quite helpful for the correct buckle. [Embodiment] Figs. 1 and 2 show a liquid medicine transfer device 1 for securely fastening a conventional medicinal vial bottle. The vial u has a longitudinal axis 12 and a bottle. Body portion 13 includes a liquid medication 14, a vial opening 16, 7 200810742, and a narrow neck 17 between the bottle body 13 and the opening 16. The opening 16 is typically plugged by a rubber base 18 having an annular head 19 and a downwardly extending tubular portion 2 having a hidden bore (Mind(10)) a having a A transverse section A1 transverse to the longitudinal axis 12. The vial 11 is sealed by an aluminum band 23 having a rounded edge 24 having an outer (four) and having a ridge around the peripheral surface 26 of the shaft and contacting the rubber stopper 18. Central area 27. The center of the rubber stopper _ 27 has - tilt _ 12 cross-cut transverse section μ, basin: = A:, _A2 > A1 design features long resulting in small body: 岐 has a row - column, because the Langer has a wrong impression, I think that they have a more realistic target range in the spurs. The body drug transfer device 1G includes a longitudinal axis 31 of a small plastic bottle adapter, and a container for receiving a syringe (not shown) ^30 Cf6maleLUer~-). The small medicine bottle adapter 3〇 includes a top wa 11 33, and an apricot tongs and a H-shaped shell _ outer edge 34, a small medicine bottle that can be freely stretched Open °16. The outer edge 34 includes three non-adjacent cis-members 37, which have a miscellaneous _ == 30 including a one-piece hollow hollow city bottle that should be connected for liquid communication, _38 with 妾 = body aperture (flow aperture) 4 There is a liquid 200810742 - Xiaole Lin retains the movable tree 36 with an inner surface 36A and tapers outward to the top of the movable jaw and has an inner diameter coffee, and a length between the top wall and the top wall. The inner surface is equipped with a small stretch of inwardly protruding ACLs 36C ' used to buckle up to the vial opening 16 for the purpose of holding the vial. When the liquid drug transfer device 1 is snapped over a small vial 11 / 'the puncture needle tip 39 extends downwardly and gently holds the support rib cage through the vial "C so that the liquid aperture 41 of the guillotine needle is parked in The vial is hidden in the bore & the small bottle guide movable member 37 has a flat inner surface 37A and extends to the top of the movable member and has an inner slave D3, and D2 > D3 > D1, and a top wall 33 The length L2 j>U. The movable 70-piece tip 37β extends downward beyond the movable element tip 36B, so that the needle edge 24 contacts the round edge 24 of the hoop before the puncture needle tip 39 contacts the vial bottle stopper. The correct (four) liquid drug delivery package is arranged in a concentric axis with the small vial. The correct design of the liquid drug delivery device 10 is designed to be torn in a small vial in 11 fields to three to three. Users tend to The body-sitting delivery device 1〇 and the small bottle 11 are incorrectly arranged, such as from the center of the liquid drug delivery device (Fig. 3Α) or at an angle to the vial u (Fig. 3). The movable element 37 assists the user in allowing the liquid drug delivery device to be placed in the same manner as the vial The shaft row contacts the rounded edge 24 of the cuff when the tip end 39 of the movable element contacts the vial stopper 18 (see Figure 3C). The liquid drug delivery device i begins to enter the vial _ , so that the small guide movable element 37 _ Lü Hing's 9 200810742 Qian Xinyi (four) Na material, paste 39 contact small pill bottle two = the bottle of the bottle under the tender gamma iron = 吏 u « 丨 guide movable element 37 Sliding the surface of the hidden hole 22 (four) H, the liquid pore 41 is in the cork (see Figure 3 ^ Connector % effective liquid AC = display - liquid drug shifting 5Q ' and liquid drug transfer device 1 〇 = 51, ° ° her side of the side of the 峨 含 含 个 个 个 个 个 个 心 心 心 心 心 心 心 心 心 心 心 心 心 心 心 心 心 心 心 心 心 心 心 心 心 心 心 心 心 心 心 心 心 心 心 心Guide the movable element 37. The crying Γ shows a coffee π liquid control device 6 〇 attached to a small pill bottle should be / separable small vial should be fresh, 61 for the full design of the ride on a medicinal vial 3d Ben & (10) will be described by a limited number of specific patterns, but 疋 1 is well known 'everything from the present invention Many variations, modifications, and other applications still fall within the scope of the following application. [Simplified Schematic] In order to understand the present invention and observe its actual operation, an example of a specific mode for implementing the cut-off field without limitation is described. The same parts of the drawings are marked with the same number, of which: 200810742 on the safety design diagram - the system - the article - the division of the teacher - the ideal profile of the example, with a small vial adapter Correctly buckled in a medicinal small medicine bottle, the second system - a liquid miscellaneous transfer device and the _ _ small vial along the Μ line longitudinal section. Figure 3 A series - a vertical section display - The liquid drug transfer device deviates from the center point for the medicinal vial. μ Medicinal vials Figure 3 B-section shows a liquid drug transfer | for medicinal purposes, angled. Figure 3C is a liquid drug transfer device and a small vial coaxially arranged to securely fasten the longitudinal section of it. Figure 2D is a liquid drug transfer device lightly sprinkle 1 彳 peach to the small vial The longitudinal section of the press is shown in Figure 3, which is a longitudinal section of the liquid medicine transfer device that is attached to the medicine and the vial and has fluid communication with the inside of the vial. The second ideal concrete mode is a schematic diagram of the example of a singularity, with a ventilated vial adapter attached to the safety design of a small medicinal vial; and Figure 5 is an endowment f liquid control Following the _ modal overview, there is a small drug _ connector with the correct design of the buckle on the _ pour bottle. 200810742 [Main component symbol description] 10···· •• Liquid drug transfer device 11·· ··••Pill bottle 12····••Longitudinal axis 13···· •• Bottle body 14····••Liquid drug 16····•• Opening 17...·••Narrow neck 18 ·.•...Rubber base 19...·••Circular head 21····••Tube 22···· ••Drilling 23...·••绍犹24...·••Round edge 26...· ••Circumferential surface 27...·••Central area 30····••Pill bottle adapter 31····••Vertical axis 32····••Concave Liu connector 33 ...· ••Top wall 34...·••Outer edge 36...·•• Movable element 36A" 36B··· Movable element tip 36C···· rib cage 37.... •• Movable element 37A·· 37B·· ...·Top 38.... ••Puncture needle 39.......tip 41·····Pore 50....Liquid drug transfer device 5l···....Small vial adapter 60...·Liquid control device 6l···· ... small vial adapter A···. ... inspection plane A2...·...edge section D1--...outer diameter Ll···....length L2·...length 12