TW200744657A - Wrinkling prevention or mitigation with adam inhibitor - Google Patents

Wrinkling prevention or mitigation with adam inhibitor

Info

Publication number
TW200744657A
TW200744657A TW095134061A TW95134061A TW200744657A TW 200744657 A TW200744657 A TW 200744657A TW 095134061 A TW095134061 A TW 095134061A TW 95134061 A TW95134061 A TW 95134061A TW 200744657 A TW200744657 A TW 200744657A
Authority
TW
Taiwan
Prior art keywords
group
mitigation
adam inhibitor
wrinkling prevention
adam
Prior art date
Application number
TW095134061A
Other languages
Chinese (zh)
Inventor
Takuya Hiruma
Hirotada Fukunishi
Masaru Suetsugu
Yukiko Matsunaga
Michio Shibata
Satoshi Amano
Original Assignee
Shiseido Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shiseido Co Ltd filed Critical Shiseido Co Ltd
Publication of TW200744657A publication Critical patent/TW200744657A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

To provide an inhibiting agent effectively preventing or mitigating wrinkles. An ADAM inhibitor composed of a benzohydroxamic acid expressed by general formula (I) or its salt is applied to the skin. In the formula (I), R1 is a 1-18C alkyl, a 3-8C cycloalkyl, a halogen atom, hydroxyl group, a 1-18C alkoxyl group, benzyloxy group, amino group or an acylamino group; R2 is H, methyl or phenyl; and n is an integer of 0-3.
TW095134061A 2005-09-29 2006-09-14 Wrinkling prevention or mitigation with adam inhibitor TW200744657A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2005283501 2005-09-29
JP2006101430A JP2007119444A (en) 2005-09-29 2006-04-03 Wrinkling prevention or mitigation with adam inhibitor

Publications (1)

Publication Number Publication Date
TW200744657A true TW200744657A (en) 2007-12-16

Family

ID=37899719

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095134061A TW200744657A (en) 2005-09-29 2006-09-14 Wrinkling prevention or mitigation with adam inhibitor

Country Status (3)

Country Link
JP (1) JP2007119444A (en)
TW (1) TW200744657A (en)
WO (1) WO2007037295A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5722030B2 (en) 2008-03-31 2015-05-20 株式会社 資生堂 Oral, injection, external skin preparation and cosmetic method for preventing or improving wrinkles
CN102272739A (en) 2009-03-24 2011-12-07 株式会社日立制作所 Storage apparatus and its data control method

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1228772A (en) * 1996-08-28 1999-09-15 普罗克特和甘保尔公司 Heterocyclic metalloprotease inhibitors
US6696449B2 (en) * 1997-03-04 2004-02-24 Pharmacia Corporation Sulfonyl aryl hydroxamates and their use as matrix metalloprotease inhibitors
US7622117B2 (en) * 2002-04-17 2009-11-24 Dynamis Therapeutics, Inc. 3-deoxyglucosone and skin
ITMI20021080A1 (en) * 2002-05-21 2003-11-21 Marcello Izzo PHARMACEUTICAL ASSOCIATIONS FOR TOPICAL USE BASED ON CHELATES OF THE METAL PROTEASIS FERROINHIBITORS AND FACTOR XIII FOR THE TREATMENT OF
US20040146539A1 (en) * 2003-01-24 2004-07-29 Gupta Shyam K. Topical Nutraceutical Compositions with Selective Body Slimming and Tone Firming Antiaging Benefits
EP1660437B1 (en) * 2003-08-26 2008-10-15 Amorepacific Corporation Hydroxamic acid derivatives and the method for preparing thereof
JP4777738B2 (en) * 2004-10-14 2011-09-21 株式会社 資生堂 Prevention or improvement of wrinkles by ADAM activity inhibitors
US20060165641A1 (en) * 2005-01-18 2006-07-27 Kumar Pillai Cosmetic compositions containing combinations of hydroxamate derivatives and antioxidants in a liposomal delivery system

Also Published As

Publication number Publication date
WO2007037295A1 (en) 2007-04-05
JP2007119444A (en) 2007-05-17

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