TW200716112A - Benzimidazole compound - Google Patents

Benzimidazole compound

Info

Publication number
TW200716112A
TW200716112A TW095113357A TW95113357A TW200716112A TW 200716112 A TW200716112 A TW 200716112A TW 095113357 A TW095113357 A TW 095113357A TW 95113357 A TW95113357 A TW 95113357A TW 200716112 A TW200716112 A TW 200716112A
Authority
TW
Taiwan
Prior art keywords
group
dioxan
dimethyl
maintaining
represent
Prior art date
Application number
TW095113357A
Other languages
Chinese (zh)
Other versions
TWI439270B (en
Inventor
Shuhei Miyazawa
Masanobu Shinoda
Tetsuya Kawahara
Nobuhisa Watanabe
Hitoshi Harada
Daisuke Iida
Hiroki Terauchi
Junichi Nagakawa
Hideaki Fujisaki
Atsuhiko Kubota
Masato Ueda
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of TW200716112A publication Critical patent/TW200716112A/en
Application granted granted Critical
Publication of TWI439270B publication Critical patent/TWI439270B/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

An object of the present invention is to provide a novel chemical compound useful as a therapeutic or prophylactic agent for acid-related diseases, having an excellent inhibitory effect against gastric acid secretion, an excellent effect of maintaining the inhibitory effect against gastric acid secretion, thereby maintaining intragastric pH high for a long time, and having more safety and appropriate physicochemical stability. Provided is a compound represented, wherein R1 and R3 may be the same or different and each represent a hydrogen atom or a C1-C6 alkyl group; R2 represents (5,5-dimethyl-1,3-dioxan-2-yl)methoxy group, 5,7-dioxaspiro[2.5]oct-6-ylmethoxy group, 1,5,9-trioxaspiro[5.5]undec-3-ylmethoxy group, or (2,2-dimethyl-1,3-dioxan-5-yl)methoxy group; R4, R5, R6 and R7 represent a hydrogen atom, halogen atom, C1-C6 alkyl group, C1-C6 haloalkyl group, C1-C6 alkoxy group or C1-C6 haloalkoxy group; and W.sup.1 represents a single bond, methylene or ethylene group, a salt thereof or a solvate of these.
TW95113357A 2005-04-15 2006-04-14 Benzimidazole compound TWI439270B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2005117643 2005-04-15
US67584805P 2005-04-29 2005-04-29

Publications (2)

Publication Number Publication Date
TW200716112A true TW200716112A (en) 2007-05-01
TWI439270B TWI439270B (en) 2014-06-01

Family

ID=39307941

Family Applications (1)

Application Number Title Priority Date Filing Date
TW95113357A TWI439270B (en) 2005-04-15 2006-04-14 Benzimidazole compound

Country Status (6)

Country Link
CN (1) CN101160306B (en)
JO (1) JO2615B1 (en)
MY (1) MY151167A (en)
SA (1) SA06270095B1 (en)
TW (1) TWI439270B (en)
ZA (1) ZA200708803B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102942523A (en) * 2012-12-05 2013-02-27 寿光富康制药有限公司 Preparation method of omeprazole intermediate 2,3,5-trimethylpyridyl-N-oxide
US8962660B2 (en) * 2013-03-14 2015-02-24 Bristol-Myers Squibb Company Oxabicyclo [2.2.2] acid GPR120 modulators
WO2016104668A1 (en) * 2014-12-26 2016-06-30 国立大学法人 東京大学 Method for producing proton pump inhibitor compound having optical activity

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8300736D0 (en) * 1983-02-11 1983-02-11 Haessle Ab NOVEL PHARMACOLOGICALLY ACTIVE COMPOUNDS

Also Published As

Publication number Publication date
CN101160306A (en) 2008-04-09
SA06270095B1 (en) 2012-01-24
TWI439270B (en) 2014-06-01
ZA200708803B (en) 2009-04-29
CN101160306B (en) 2011-11-02
MY151167A (en) 2014-04-30
JO2615B1 (en) 2011-11-01

Similar Documents

Publication Publication Date Title
NO20075904L (en) benzimidazole
TW200633991A (en) Chemical compounds
WO2008108380A3 (en) Pyrrole compounds
WO2011004162A3 (en) 1, 2, 4-thiazolidin-3-one derivatives and their use in the treatment of cancer
EA200801608A1 (en) DERIVATIVES OF BENZIMIDAZOLONIC CARBONIC ACID
WO2008075172A3 (en) Nicotinamide derivatives as inhibitors of h-pgds and their use for treating prostaglandin d2 mediated diseases
MXPA05009969A (en) Methods for isolating crystalline form i of 5-azacytidine.
TW200626610A (en) Analogs of 17-hydroxywortmannin as PI3K inhibitors
NO20064032L (en) DPP-IV inhibitors
EA200601847A1 (en) Substituted Methylaryl or Heteroaryl Amide Compounds
TW200642683A (en) Heterocyclic compound
MX2010002662A (en) Spirocyclic aminoquinolones as gsk-3 inhibitors.
WO2009079008A8 (en) Benzopyrans and analogs as rho kinase inhibitors
NO20092286L (en) Nitrogen-containing heterocyclic compounds and their use
NO20065320L (en) Imidazole derivatives used as suppository inhibitors
WO2007103550A3 (en) Substituted aminothiazole derivatives with anti-hcv activity
WO2005073214A3 (en) Novel inhibitors of chymase
MY149180A (en) Uracil compound having inhibitor activity on human deoxyuridine triphosphatase or salt thereof
NO20085107L (en) Spirocyclic nitriles as protease inhibitors
WO2009121033A3 (en) Substituted nitrogen heterocycles and synthesis and uses thereof
MX2016006685A (en) N-acylimino heterocyclic compounds.
WO2009116067A3 (en) Novel derivatives of acyl cyanopyrrolidines
TW200613292A (en) Benzothiazolium compounds
EA201071012A1 (en) DERIVATIVES OF AZETIDINE, METHOD OF THEIR RECOVERY AND USE OF THEM IN THERAPY
DE502006008710D1 (en) SUBSTITUTED TETRAHYDROISOCHINOLINES AS MMP INHIBITORS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A MEDICAMENT

Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees