TW200609001A - Particulate-stabilized injectable pharmaceutical compositions of posaconasole - Google Patents

Particulate-stabilized injectable pharmaceutical compositions of posaconasole

Info

Publication number
TW200609001A
TW200609001A TW094117524A TW94117524A TW200609001A TW 200609001 A TW200609001 A TW 200609001A TW 094117524 A TW094117524 A TW 094117524A TW 94117524 A TW94117524 A TW 94117524A TW 200609001 A TW200609001 A TW 200609001A
Authority
TW
Taiwan
Prior art keywords
posaconasole
particulate
pharmaceutical compositions
injectable pharmaceutical
stabilized injectable
Prior art date
Application number
TW094117524A
Other languages
Chinese (zh)
Other versions
TWI290051B (en
Inventor
Leonore Witchey-Lakshmanan
Sydney Ugwu
Varda Sandweiss
Catherine Hardalo
Roberta S Hare
Gopal Krishna
Zaiqi Wang
Marco Taglietti
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34971355&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TW200609001(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of TW200609001A publication Critical patent/TW200609001A/en
Application granted granted Critical
Publication of TWI290051B publication Critical patent/TWI290051B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

The present invention provides formulations useful for treating infections, in particular, formulations that include the active pharmaceutical ingredient posaconazole in an injectable suspension that is stable when subjected to terminal steam sterilization.
TW094117524A 2004-05-28 2005-05-27 Particulate-stabilized injectable pharmaceutical compositions of Posaconazole TWI290051B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57512604P 2004-05-28 2004-05-28

Publications (2)

Publication Number Publication Date
TW200609001A true TW200609001A (en) 2006-03-16
TWI290051B TWI290051B (en) 2007-11-21

Family

ID=34971355

Family Applications (1)

Application Number Title Priority Date Filing Date
TW094117524A TWI290051B (en) 2004-05-28 2005-05-27 Particulate-stabilized injectable pharmaceutical compositions of Posaconazole

Country Status (15)

Country Link
EP (1) EP1761247A1 (en)
JP (1) JP2008501034A (en)
KR (1) KR20070027564A (en)
CN (1) CN1988887A (en)
AR (1) AR049063A1 (en)
AU (1) AU2005249502A1 (en)
CA (1) CA2567803A1 (en)
IL (1) IL179627A0 (en)
MX (1) MXPA06013886A (en)
NO (1) NO20066005L (en)
PE (1) PE20060291A1 (en)
RU (1) RU2006146555A (en)
TW (1) TWI290051B (en)
WO (1) WO2005117831A1 (en)
ZA (1) ZA200609890B (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060009469A1 (en) * 2004-05-28 2006-01-12 Leonore Witchey-Lakshmanan Particulate-stabilized injectable pharmacutical compositions of posaconazole
CA2651726C (en) 2006-05-12 2015-12-15 Pharmacon - Forschung Und Beratung Gmbh Use of combination preparations, comprising antimycotics
EP2130540A1 (en) 2008-06-02 2009-12-09 Sandoz AG Pharmaceutical compositions containing a crystalline form of posaconazole
EP2141159A1 (en) 2008-07-03 2010-01-06 Sandoz AG A Crystalline form of posaconazole
CA2767489A1 (en) 2009-07-09 2011-01-13 Sandoz Ag A crystalline form of posaconazole
MX337804B (en) 2010-05-19 2016-03-18 Sandoz Ag Process for the preparation of chiral hydrazides.
EP2571868B1 (en) 2010-05-19 2016-05-04 Sandoz AG Preparation of posaconazole intermediates
MX2012013331A (en) 2010-05-19 2013-02-01 Sandoz Ag Purification of posaconazole and of posaconazole intermediates.
EP2571871B1 (en) 2010-05-19 2017-06-21 Sandoz AG Process for the preparation of chiral triazolones
BR112012033077B8 (en) 2010-06-29 2023-04-25 Merck Sharp & Dohme PHARMACEUTICAL COMPOSITION FOR INTRAVENOUS ADMINISTRATION, USE OF A PHARMACEUTICAL COMPOSITION, AND, KIT
WO2012172015A1 (en) 2011-06-16 2012-12-20 Sandoz Ag Process for the preparation of a chiral compound
CN103284959B (en) * 2012-02-22 2015-06-03 重庆圣华曦药业股份有限公司 Posaconazole freeze-dried powder injection and preparation method thereof
CN102755628B (en) * 2012-07-16 2013-10-23 中国科学院微生物研究所 Antifungal pharmaceutical composition
CN102805731B (en) * 2012-08-22 2014-04-30 北京莱瑞森医药科技有限公司 Posaconazole dry suspension and preparation method thereof
CN105030668B (en) * 2015-06-26 2018-03-27 济川药业集团有限公司 Oral posaconazole supensoid agent and preparation method thereof
CN106333925B (en) * 2015-07-10 2019-06-18 上海美悦生物科技发展有限公司 A kind of posaconazole liquid suspension and preparation method thereof
CN105997872B (en) * 2016-07-08 2019-02-19 河南省立眼科医院 A kind of antimycotic solution of ophthalmically acceptable nano-micelle containing posaconazole
WO2018182562A1 (en) * 2017-03-26 2018-10-04 Stafford Vivi Robyn Method of treatment of skin conditions of eye lids
EP3609329A4 (en) * 2017-04-12 2021-03-17 Bhagwandin, Vikash J. Compositions, packaged pharmaceuticals, and methods of using posaconazole for the sensitization of resistant tumors
CN110507609B (en) * 2018-05-21 2021-09-17 上海医药工业研究院 Preparation method of posaconazole oral suspension
CN111514146A (en) * 2020-04-28 2020-08-11 山西振东泰盛制药有限公司 Pharmaceutical composition containing posaconazole
CN113933131B (en) * 2021-09-24 2024-01-26 合肥天一生物技术研究所有限责任公司 Vaginal microorganism fluorescent staining solution

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5091188A (en) * 1990-04-26 1992-02-25 Haynes Duncan H Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs
KR100607742B1 (en) * 2001-04-03 2006-08-01 쉐링 코포레이션 Antifungal composition with enhanced bioavailability

Also Published As

Publication number Publication date
JP2008501034A (en) 2008-01-17
RU2006146555A (en) 2008-07-20
KR20070027564A (en) 2007-03-09
AR049063A1 (en) 2006-06-21
ZA200609890B (en) 2008-09-25
MXPA06013886A (en) 2007-01-26
WO2005117831A1 (en) 2005-12-15
PE20060291A1 (en) 2006-04-14
AU2005249502A1 (en) 2005-12-15
EP1761247A1 (en) 2007-03-14
CN1988887A (en) 2007-06-27
CA2567803A1 (en) 2005-12-15
TWI290051B (en) 2007-11-21
NO20066005L (en) 2007-02-27
IL179627A0 (en) 2007-05-15

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Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees