TW200608968A - Tetrasubstituted imidazole derivatives as cannabinoid cb1 receptor modulators with a high cb1/cb2 receptor subtype selectivity - Google Patents
Tetrasubstituted imidazole derivatives as cannabinoid cb1 receptor modulators with a high cb1/cb2 receptor subtype selectivityInfo
- Publication number
- TW200608968A TW200608968A TW094116864A TW94116864A TW200608968A TW 200608968 A TW200608968 A TW 200608968A TW 094116864 A TW094116864 A TW 094116864A TW 94116864 A TW94116864 A TW 94116864A TW 200608968 A TW200608968 A TW 200608968A
- Authority
- TW
- Taiwan
- Prior art keywords
- receptor
- art
- relates
- imidazole derivatives
- disclosed
- Prior art date
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
The present invention relates to 1,2,4,5-tetrasubstituted imidazole derivatives as selective cannabinoid CB1 receptor modulators, in particular CB1 receptor antagonists or inverse agonists having a high CB1/CB2 receptor subtype selectivity, to methods for the preparation of these compounds and to novel intermediates useful for the synthesis of said imidazole derivatives. The invention also relates to the use of a compound disclosed herein for the manufacture of a medicament giving a beneficial effect. A beneficial effect is disclosed herein or apparent to a person skilled in the art from the specification and general knowledge in the art. The invention also relates to the use of a compound of the invention for the manufacture of a medicament for treating or preventing a disease or condition. More particularly, the invention relates to a new use for the treatment of a disease or condition disclosed herein or apparent to a person skilled in the art from the specification and general knowledge in the art. In embodiments of the invention specific compounds disclosed herein are used for the manufacture of a medicament useful in the treatment of psychiatric and neurological disorders. The compounds have the general formula (1), , wherein the symbols have the meanings given in the specification.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04076619 | 2004-05-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
TW200608968A true TW200608968A (en) | 2006-03-16 |
Family
ID=34928258
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW094116864A TW200608968A (en) | 2004-05-28 | 2005-05-24 | Tetrasubstituted imidazole derivatives as cannabinoid cb1 receptor modulators with a high cb1/cb2 receptor subtype selectivity |
Country Status (5)
Country | Link |
---|---|
CN (1) | CN1956965B (en) |
AR (1) | AR052763A1 (en) |
SA (1) | SA05260148B1 (en) |
TW (1) | TW200608968A (en) |
UA (1) | UA85239C2 (en) |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI231757B (en) * | 2001-09-21 | 2005-05-01 | Solvay Pharm Bv | 1H-Imidazole derivatives having CB1 agonistic, CB1 partial agonistic or CB1-antagonistic activity |
-
2005
- 2005-05-24 AR ARP050102138 patent/AR052763A1/en not_active Application Discontinuation
- 2005-05-24 TW TW094116864A patent/TW200608968A/en unknown
- 2005-05-25 SA SA05260148A patent/SA05260148B1/en unknown
- 2005-05-26 CN CN2005800162950A patent/CN1956965B/en not_active Expired - Fee Related
- 2005-05-26 UA UAA200613783A patent/UA85239C2/en unknown
Also Published As
Publication number | Publication date |
---|---|
UA85239C2 (en) | 2009-01-12 |
CN1956965A (en) | 2007-05-02 |
SA05260148B1 (en) | 2008-11-15 |
AR052763A1 (en) | 2007-04-04 |
CN1956965B (en) | 2011-03-23 |
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