TW200512295A - Method for the gene transfer mediated by implused magnetic fields - Google Patents
Method for the gene transfer mediated by implused magnetic fieldsInfo
- Publication number
- TW200512295A TW200512295A TW092126270A TW92126270A TW200512295A TW 200512295 A TW200512295 A TW 200512295A TW 092126270 A TW092126270 A TW 092126270A TW 92126270 A TW92126270 A TW 92126270A TW 200512295 A TW200512295 A TW 200512295A
- Authority
- TW
- Taiwan
- Prior art keywords
- gene transfer
- cells
- gene
- dna
- nucleic acid
- Prior art date
Links
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
A method is disclosed for transferring genetic materials like DNA into cells by applying a strong magnetic field in pulses. To mediate the gene transfer, cells and nucleic acid construct are mixed and exposed in pulsed magnetic field once or several times. Cells receiving the DNA in the cytoplasm and then nuclei, where the gene products encoded in DNA are expressed transiently or continuously. The nucleic acid construct can be either magnetic or non-magnetic. However, the use of superparamagnetic nanoparticles for the formation of nucleic acid construct, the efficiency of gene transfer can be promoted. The present invention discloses a simple and fast method for gene transfer to cells for the application in gene therapy, gene transfcetion, and drug delivery.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
TW092126270A TW200512295A (en) | 2003-09-23 | 2003-09-23 | Method for the gene transfer mediated by implused magnetic fields |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
TW092126270A TW200512295A (en) | 2003-09-23 | 2003-09-23 | Method for the gene transfer mediated by implused magnetic fields |
Publications (1)
Publication Number | Publication Date |
---|---|
TW200512295A true TW200512295A (en) | 2005-04-01 |
Family
ID=57798605
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW092126270A TW200512295A (en) | 2003-09-23 | 2003-09-23 | Method for the gene transfer mediated by implused magnetic fields |
Country Status (1)
Country | Link |
---|---|
TW (1) | TW200512295A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11442117B2 (en) | 2016-11-09 | 2022-09-13 | Sigma Genetics, Inc. | Systems, devices, and methods for electroporation induced by magnetic fields |
-
2003
- 2003-09-23 TW TW092126270A patent/TW200512295A/en unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11442117B2 (en) | 2016-11-09 | 2022-09-13 | Sigma Genetics, Inc. | Systems, devices, and methods for electroporation induced by magnetic fields |
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