TR2021019717A2 - USAGE OF BEE SILK FOR MEDICAL AND COSMETIC PURPOSES - Google Patents
USAGE OF BEE SILK FOR MEDICAL AND COSMETIC PURPOSESInfo
- Publication number
- TR2021019717A2 TR2021019717A2 TR2021/019717A TR2021019717A TR2021019717A2 TR 2021019717 A2 TR2021019717 A2 TR 2021019717A2 TR 2021/019717 A TR2021/019717 A TR 2021/019717A TR 2021019717 A TR2021019717 A TR 2021019717A TR 2021019717 A2 TR2021019717 A2 TR 2021019717A2
- Authority
- TR
- Turkey
- Prior art keywords
- bee
- silk
- bee silk
- wax
- specified
- Prior art date
Links
- 239000002537 cosmetic Substances 0.000 title claims abstract description 9
- 238000000034 method Methods 0.000 claims abstract description 15
- 238000004519 manufacturing process Methods 0.000 claims abstract description 14
- 239000001993 wax Substances 0.000 claims abstract description 14
- 239000002904 solvent Substances 0.000 claims abstract description 10
- 235000013871 bee wax Nutrition 0.000 claims abstract description 7
- 239000006071 cream Substances 0.000 claims abstract description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 7
- 238000009835 boiling Methods 0.000 claims abstract description 6
- 239000000463 material Substances 0.000 claims abstract description 6
- 239000000203 mixture Substances 0.000 claims abstract description 5
- 239000000835 fiber Substances 0.000 claims abstract description 4
- 210000002966 serum Anatomy 0.000 claims abstract description 4
- 238000001523 electrospinning Methods 0.000 claims abstract description 3
- 239000000839 emulsion Substances 0.000 claims abstract description 3
- 230000035876 healing Effects 0.000 claims abstract description 3
- 239000006210 lotion Substances 0.000 claims abstract description 3
- 238000005406 washing Methods 0.000 claims abstract description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 6
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 6
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 claims description 6
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims description 4
- 239000004744 fabric Substances 0.000 claims description 4
- 229910000831 Steel Inorganic materials 0.000 claims description 2
- 238000001035 drying Methods 0.000 claims description 2
- 238000002844 melting Methods 0.000 claims description 2
- 230000008018 melting Effects 0.000 claims description 2
- 239000002184 metal Substances 0.000 claims description 2
- 239000002245 particle Substances 0.000 claims description 2
- 239000011148 porous material Substances 0.000 claims description 2
- 238000003825 pressing Methods 0.000 claims description 2
- 239000010959 steel Substances 0.000 claims description 2
- 239000012166 beeswax Substances 0.000 claims 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 2
- 239000008278 cosmetic cream Substances 0.000 claims 1
- 239000008341 cosmetic lotion Substances 0.000 claims 1
- 238000004945 emulsification Methods 0.000 claims 1
- 238000004108 freeze drying Methods 0.000 claims 1
- 238000007710 freezing Methods 0.000 claims 1
- 230000008014 freezing Effects 0.000 claims 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 1
- 238000000926 separation method Methods 0.000 abstract description 5
- 238000004061 bleaching Methods 0.000 abstract description 4
- 238000004140 cleaning Methods 0.000 abstract description 4
- 238000002156 mixing Methods 0.000 abstract description 4
- 230000003020 moisturizing effect Effects 0.000 abstract description 4
- 230000001153 anti-wrinkle effect Effects 0.000 abstract description 3
- 230000000845 anti-microbial effect Effects 0.000 abstract description 2
- 230000003779 hair growth Effects 0.000 abstract description 2
- 230000001172 regenerating effect Effects 0.000 abstract description 2
- 230000000475 sunscreen effect Effects 0.000 abstract description 2
- 239000000516 sunscreening agent Substances 0.000 abstract description 2
- 230000029663 wound healing Effects 0.000 abstract description 2
- 241000264877 Hippospongia communis Species 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 241000256844 Apis mellifera Species 0.000 description 19
- 102000004169 proteins and genes Human genes 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- 230000008901 benefit Effects 0.000 description 3
- 239000012620 biological material Substances 0.000 description 2
- 241000256846 Apis cerana Species 0.000 description 1
- 241000239290 Araneae Species 0.000 description 1
- 241000255789 Bombyx mori Species 0.000 description 1
- 241000510032 Ellipsaria lineolata Species 0.000 description 1
- 241000257303 Hymenoptera Species 0.000 description 1
- 108020004511 Recombinant DNA Proteins 0.000 description 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 description 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 125000003275 alpha amino acid group Chemical group 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 239000000560 biocompatible material Substances 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 210000001520 comb Anatomy 0.000 description 1
- 239000000446 fuel Substances 0.000 description 1
- 150000002334 glycols Chemical class 0.000 description 1
- 239000007952 growth promoter Substances 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000005445 natural material Substances 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000014616 translation Effects 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K59/00—Honey collection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/10—General cosmetic use
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Insects & Arthropods (AREA)
- Birds (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Husbandry (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Buluş, arı mumundan arı ipeğinin ayrıştırılması, temizlenmesi, ağartılması sonrası ham arı ipeğinin eldesi ve sonrasında değişik işlemlerden geçirilerek ürünlere karıştırılması ile ilgilidir. Buluş, arı mumundan arı ipeğinin ayrıştırılması, temizlenmesi, ağartılması sonrası ham arı ipeğinin eldesi ve sonrasında değişik işlemlerden geçirilerek ürünlere karıştırılması ile ilgilidir. Ham arı peteklerinin içerisinde bulunan gözler içerisinde ince bir tabaka halinde bulunan arı ipeklerin bir seri fiziksel işlem ile ayrıştırılması için eritilmesi, filtre ile basınç altında balmumumun ayrılması, arta kalan posanın yeniden kaynayan su içerisinde yıkanması ile mumlardan arındırılmasını müteakiben değişik çözgenlerden geçirilmesi ile ağartılması ile arı ipeğinin saf olarak elde edilmesini içermektedir. Saf arı ipeklerinin toz hale getirildikten medikal amaçlı ve kozmetik amaçlı yara iyileştirici, antimikrobiyal, hücre yenileyici, kırışık önleyici, nemlendirici, saç çıkmasını teşvik edici, saç bakım kremi, nemlendirici krem, güneş kremi, göz kremi, losyon ve serumların içerisine kullanım oranı en az %0,1 olacak şekilde, karışımın emülsifiye edilmesi aşamasında, öncesinde veya sonrası katılmasının sağlanmasıdır. Yine arı ipeğinin yara örtüsü, yara bandı gibi materyaller üzerine fiziksel olarak tutundurulması, elektro eğirme ile oluşturulan liflere bağlanması, yıkama çözgeninde oluşturulan emülsiyonun emdirilmesi ile arı ipeği esaslı iyileştirici ekipmanların üretiminde kullanılmasının sağlanmasıdır.The invention relates to the separation of bee silk from bee wax, cleaning, obtaining raw bee silk after bleaching and then mixing it into products by going through different processes. The invention relates to the separation of bee silk from bee wax, cleaning, obtaining raw bee silk after bleaching and then mixing it into products by going through different processes. The bee silk, which is in a thin layer in the cells inside the raw bee honeycombs, is melted for separation by a series of physical processes, the wax is separated under pressure with a filter, the remaining pulp is washed again in boiling water, cleared of waxes, and then the bee silk is bleached by passing it through various solvents. It includes obtaining it in pure form. After the pure bee silk is powdered, the rate of use in wound healing, antimicrobial, cell regenerative, anti-wrinkle, moisturizing, hair growth promoting, hair care cream, moisturizing cream, sunscreen, eye cream, lotion and serums for medical and cosmetic purposes is at least It is to add 0.1% of the mixture before or after it is emulsified. Again, bee silk is physically attached to materials such as dressings, band-aids, bonded to fibers formed by electrospinning, impregnating the emulsion formed in the washing solvent and being used in the production of bee silk-based healing equipment.
Description
TARIFNAME ARI IPEGININ MEDIKAL VE KOZMETIK AMAÇLA KULLANIMI Buiusun iiqiii oiduöiu Teknik Saha Bulus, ari mumundan ari ipeginin ayristirilmasi, temizlenmesi, agartilmasi sonrasi ham ari ipeginin eldesi ve sonrasinda degisik islemlerden geçirilerek ürünlere karistirilmasi ile ilgilidir. DESCRIPTION USE OF BEE SILK FOR MEDICAL AND COSMETIC PURPOSES Buiusun iiqiii oiduöiu Technical Field The invention was the separation, cleaning and bleaching of bee silk from bee wax. Afterwards, raw bee silk is obtained and then processed into products. It's about mixing.
Teknigin Bilinen Durumu Arilar tarafindan Iarvalarin etrafinda örülen protein esasli dogal madde ari ipegi olarak bilinmekte olup, balmumunda petek gözlerinin içerisinde ince zar seklinde bulunmaktadir. Bu hali ile balmumunun islenmesi esnasinda posa ile atilmakta hiçbir sekilde ayrilamamaktadir. Bir balmumunun kovan içerisindeki yasi ilerledikçe, içerisinde daha fazla yavru çiktikça bu ipek kat kat kalinlasmaktadir ve mum üretiminde posadaki orani artmaktadir. Mevcut tekniklerde bu ipek hiçbir sekilde kullanilmamakta, atik kati yakit olarak yakilirken ipek materyal de yakilmaktadir. Known Status of the Technique Protein-based natural substance woven around larvae by bees. It is known as silk, and consists of a thin membrane inside the honeycomb cells of wax. It is available in the form. In this state, during the processing of the wax, it is mixed with pulp. It is thrown away and cannot be separated in any way. The age of a wax in the hive As it progresses and more babies emerge, this silk becomes thicker and thicker. Its proportion in the pulp increases in candle production. With current techniques, this silk has no It is not used in any way, and while the waste solid is burned as fuel, the silk material is also used. is being burned.
Ari ipegi kimyasal yapi itibariyle bilinen (ipek böcegi, örümcek, kelebek vs...) tüm ipeklerden farkli bir bilesime sahiptir. Proteinlerin üç boyutlu yapilari ve aminoasit zincirleri itibariyle essiz bir üründür. Bee silk is known by its chemical structure (silkworm, spider, butterfly, etc.). It has a different composition than all silks. Three-dimensional structures of proteins and amino acids It is a unique product in terms of its chains.
Ari ipegi ile ilgili simdiye kadar yapilmis ve bu ürünün katma degerli bir hale dönüstürülmesine yönelik herhangi bir patent veya yayin bulunmamaktadir. What has been done so far about bee silk and how this product can be turned into a value-added There is no patent or publication regarding its conversion.
Nadir birkaç çalismada (Shi et al., 2008; Weisman et al., 2010) ari ipeginin rekombinant DNA teknikleri ile üretilmesine yönelik arastirmalar mevcuttur. Bunlarda da ürünün katma degerine yönelik bir çalisma yapilmamis ve öngörülmemistir. In a few rare studies (Shi et al., 2008; Weisman et al., 2010), bee silk There is research on its production with recombinant DNA techniques. in these No study has been conducted or foreseen regarding the added value of the product.
Bulusun Çözümünü Amaçladigi Teknik Problemler Teknik oldukça degerli bir biomateryal olan ari ipeginin tibbi amaçlarla ve kozmetik endüstrisinde kullanilmasina yönelik olup, biyolojik açidan dogal ve biyo- uyumlu materyalin insan sagligi amaciyla kullanilmasi amaçlamaktadir. Aminoasit zinciri ve ipek proteininin üç boyutlu yapisinin olusturulacak karisimlarda ve sistemlerde kullanimi ile biyolojik yararlarin ürünlere aktarimi saglanacaktir. Technical Problems That the Invention Aims to Solve The technique is to use bee silk, a very valuable biomaterial, for medical purposes and It is intended for use in the cosmetic industry and is biologically natural and bio-friendly. It is intended to use compatible material for human health purposes. Amino acid chain and the three-dimensional structure of silk protein in the mixtures to be formed and With its use in systems, biological benefits will be transferred to the products.
Bulusun Açiklamasi Bulus, ari mumundan ari ipeginin ayristirilmasi, temizlenmesi, agartilmasi sonrasi ham ari ipeginin eldesi ve sonrasinda degisik islemlerden geçirilerek ürünlere karistirilmasi ile ilgilidir. Description of the invention The invention was the separation, cleaning and bleaching of bee silk from bee wax. Afterwards, raw bee silk is obtained and then processed into products. It's about mixing.
Ham ari peteklerinin içerisinde bulunan gözler içerisinde ince bir tabaka halinde bulunan ari ipeklerin bir seri fiziksel islem ile ayristirilmasi için mumun en az 1 kati su içerisinde eriyinceye kadar kaynatilarak eritilmesi, gözenek çapi en az 0,1 mm olan herhangi bir filtre malzemesi ile (kumas, file, örme çelik, delikli metal, çuval, örme kumas vb...) en az 0,5 kg/cm2 basinç ile preslenerek balmumumun ayrilmasi, arta kalan posanin yeniden kaynayan su içerisinde en az 2 kez daha bekletilerek mumlardan arindirilmasidir. Elde kalan posa ari ipegi bakimindan oldukça zengin bir karisim olup, kaynayan suyun yüzeyinde mum kalmayincaya kadar su degistirilerek bu islemin tekrar edilmesidir. Temizlenmis posadan geri kalan en ipeginin daha sonra degisik çözgenlerden geçirilmesi ile agartilmasi saglanacaktir. Ari ipeginin renginin açilmasi ve safsizliklarin giderilmesi için etanol veya metanol veya hegzan veya kloroform veya glikoller gibi çözgenler ile ari ipeginin en az 1 kati çözgen ile muamele edilmesi, bu islemin en az 2 kez olacak sekilde renk açilincaya kadar yapilmasinin saglanmasidir. A thin layer inside the eyes inside the raw bee combs. In order to separate the pure silks in the form of pure silk through a series of physical processes, the wax must be at least Melting by boiling until it dissolves in 1 layer of water, pore diameter of at least 0.1 mm (fabric, mesh, knitted steel, perforated metal, burlap, Separating the wax by pressing (knitted fabric, etc.) with a pressure of at least 0.5 kg/cm2, by keeping the remaining pulp in boiling water for at least 2 more times. is to purify it from waxes. The remaining pulp is very rich in terms of bee silk. mixture, changing the water until there is no wax left on the surface of the boiling water. This is the repetition of the process. The remaining silk from the cleaned pulp is then It will be bleached by passing it through different solvents. The color of Aryan silk ethanol or methanol or hexane for opening and removing impurities or Treatment with solvents such as chloroform or glycols at least 1 times the solvent of bee silk Doing this process at least 2 times until the color lightens is to ensure.
Süzülüp çözgeni ayrilmis ari ipeklerinin etüvde veya açik ortamda veya vakumlu ortamda veya mikrodalgali kurutucuda veya dondurularak kurutucuda 100°C`i geçmeyecek sekilde kurutulmasi ile saf ari ipekleri elde edilecektir. Saf ari ipekleri 0 °C ve alti sicaklikta en az 5 dakika tutulduktan sonra toz hale getirilmek üzere parçalanacaktir. Partikül büyüklügü 0,25 mm ve daha altina düstügünde tibbi amaçli ve kozmetik amaçli yara iyilestirici, antimikrobiyal, hücre yenileyici, kirisik önleyici, nemlendirici, saç çikmasini tesvik edici, saç bakim kremi, nemlendirici krem, günes kremi, göz kremi, losyon ve serumlarin içerisine kullanim orani en az sonrasi katilmasinin saglanmasidir. Drained and solvent-separated bee silks are processed in an oven or in an open environment or vacuum or microwave dryer or freeze dryer Pure bee silk will be obtained by drying at a temperature not exceeding 100°C. pure bee The silks are kept at 0 °C and below for at least 5 minutes and then pulverized. It will be broken into pieces. When the particle size is 0.25 mm or less, medical Wound healing, antimicrobial, cell regenerating, anti-wrinkle, anti-wrinkle and cosmetic products preventive, moisturizing, hair growth promoter, hair care cream, moisturizing Minimum use in creams, sunscreens, eye creams, lotions and serums. The next thing is to ensure participation.
Yine ari ipeginin yara örtüsü, yara bandi gibi materyaller üzerine fiziksel olarak tutundurulmasi, elektro egirme ile olusturulan liflere baglanmasi, yikama çözgeninde olusturulan emülsiyonun emdirilmesi ile ari ipegi esasli iyilestirici ekipmanlarin üretiminde kullanilmasinin saglanmasidir. Again, bee silk can be physically applied to materials such as wound dressings and band-aids. attachment to fibers formed by electrospinning, in washing solvent By impregnating the created emulsion, bee silk based healing equipment is applied. ensuring its use in production.
Bu bulus konusu yöntemde tasarlanan ari ipeginin medikal ve kozmetik amaçli kullanimi ile insan faydasi için yeni ürünlerin üretimi gerçeklestirilecektir. Ürün tamamen dogal olup biyouyumlu bir materyal olmasi nedeniyle avantaj saglayacaktir. The bee silk designed in the method of this invention is used for medical and cosmetic purposes. With its use, new products will be produced for human benefit. Product It will provide an advantage because it is completely natural and a biocompatible material.
Bulusun Sanayiye Uygulanma Biçimi Ari ipeginin medikal ve kozmetik amaçli kullanimi endüstriyel ve laboratuvar ortaminda seri üretim halinde rahatlikla üretilerek, artik degerli bir ürünün katma degeri yüksek bir ürüne dönüsmesi saglanarak, biyomateryal olan bir ürünün rahatlikla kullanilabilecegi, ürünlerle tüketiciye sunulabilir. Üretim fabrika/laboratuvar ortaminda seri üretime uygun olup pazarda yer bulma potansiyeli mevcuttur. How the Invention is Applied to Industry The use of bee silk for medical and cosmetic purposes has been used in industrial and laboratory It can be easily produced in mass production environment and now a valuable product can be added By ensuring that a biomaterial product is transformed into a high value product, It can be offered to the consumer with products that can be used easily. Production factory/laboratory It is suitable for mass production in the environment and has the potential to find a place in the market.
Bu basvuru koruma kapsami, istemler kisminda belirlenmis olup, yukarida kesinlikle örnekleme amaciyla anlatilanlarla sinirli tutulamaz. Teknikte uzman bir kisinin, bulusta ortaya konan yeniligi, islem basmaklarini degistirmek ve benzer yapilanmalari kullanarak benzer amaçli diger alanlara da uygulayabilecegi açiktir. The scope of protection for this application is determined in the claims section and is stated above. It certainly cannot be limited to what is explained for exemplary purposes. An expert in technology The innovation of the invention, changing the process steps and similar It is clear that it can be applied to other areas with similar purposes using these structures.
Dolayisi ile böyle yapilanmalarin yenilik kriterinden yoksun olacagi da asikardir. o Shi, J., Lua, S., Du` N., Liu, X., ve Song, J. 2008. “Identification, recombinant production and structural characterization of four silk proteins from the Asiatic honeybee Apis cerana”, i Weisman, S., Haritos, V.S., Church, J.S., Huson, MG., Mudie, S.T., Rodgers, A.J., ve Sutherland, T.D. 2010. “Honeybee silk: Recombinant protein production, assembly and fiber Therefore, it is obvious that such structures will lack the innovation criterion. o Shi, J., Lua, S., Du` N., Liu, X., and Song, J. 2008. “Identification, recombinant production and “structural characterization of four silk proteins from the Asiatic honeybee Apis cerana”, i Weisman, S., Haritos, V.S., Church, J.S., Huson, MG., Mudie, S.T., Rodgers, A.J., and Sutherland, T.D. 2010. “Honeybee silk: Recombinant protein production, assembly and fiber
Claims (9)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TR2021/019717A TR2021019717A2 (en) | 2021-12-13 | 2021-12-13 | USAGE OF BEE SILK FOR MEDICAL AND COSMETIC PURPOSES |
| PCT/TR2021/051702 WO2023113714A1 (en) | 2021-12-13 | 2021-12-31 | Use of honeybee silk for medical and cosmetic purposes |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TR2021/019717A TR2021019717A2 (en) | 2021-12-13 | 2021-12-13 | USAGE OF BEE SILK FOR MEDICAL AND COSMETIC PURPOSES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR2021019717A2 true TR2021019717A2 (en) | 2022-01-21 |
Family
ID=85116598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2021/019717A TR2021019717A2 (en) | 2021-12-13 | 2021-12-13 | USAGE OF BEE SILK FOR MEDICAL AND COSMETIC PURPOSES |
Country Status (2)
| Country | Link |
|---|---|
| TR (1) | TR2021019717A2 (en) |
| WO (1) | WO2023113714A1 (en) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2010286333B2 (en) * | 2009-08-26 | 2017-01-05 | Commonwealth Scientific And Industrial Research Organisation | Processes for producing silk dope |
| EP2824168B1 (en) * | 2013-07-08 | 2015-09-23 | Hardy Gerster | Method and device for the purification of beeswax |
| TR201507045A2 (en) * | 2015-06-09 | 2016-12-21 | Yildiz Oktay | REMOVAL OF WAX REMOVALS BY CHEMICAL AND BIOSORBSION |
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2021
- 2021-12-13 TR TR2021/019717A patent/TR2021019717A2/en unknown
- 2021-12-31 WO PCT/TR2021/051702 patent/WO2023113714A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2023113714A1 (en) | 2023-06-22 |
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