TR200607443T1 - Proteins encoding corynebacterium glutamicum in membrane synthesis and membrane transplantation - Google Patents
Proteins encoding corynebacterium glutamicum in membrane synthesis and membrane transplantationInfo
- Publication number
- TR200607443T1 TR200607443T1 TR2006/07443T TR200607443T TR200607443T1 TR 200607443 T1 TR200607443 T1 TR 200607443T1 TR 2006/07443 T TR2006/07443 T TR 2006/07443T TR 200607443 T TR200607443 T TR 200607443T TR 200607443 T1 TR200607443 T1 TR 200607443T1
- Authority
- TR
- Turkey
- Prior art keywords
- mct
- membrane
- nucleic acid
- acid molecules
- proteins
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Corynebacterium glutamicum'dan türetilmiş yeni MCT proteinlerini şifreleyen MCT nükleik asit molekülleri adlı izole edilmiş nükleik asit molekülleri tarif edilmektedir. Buluş anti duyarlı nükleik asit molekülleri, MCT nükleik asit molekülleri ihtivaeden yemden birleştirici tanım vektörleri ve tanım vektörlerinin yerleştirildiği konakçı hücreler de sağlar. Hali hazırda buluş ayrıca izole edilmiş MCT proteinleri, mutasyon geçirmiş MCT proteinleri, füzyon proteinleri, antijenik peptitler ve bu organizmadaki MCT genlerinin genetik mühendisliğine dayanarak arzu edilen bir bileşiğin C. Glutamicum'dan üretiminin geliştirilmesine yönelik metotlar sağlar.Isolated nucleic acid molecules called MCT nucleic acid molecules encoding novel MCT proteins derived from Corynebacterium glutamicum are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing MCT nucleic acid molecules, and host cells into which expression vectors have been introduced. Currently, the invention also provides isolated MCT proteins, mutated MCT proteins, fusion proteins, antigenic peptides, and methods for improving the production of a desired compound from C. glutamicum based on genetic engineering of MCT genes in this organism.
Applications Claiming Priority (35)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14103199P | 1999-06-25 | 1999-06-25 | |
DE19931563 | 1999-07-08 | ||
DE19931478 | 1999-07-08 | ||
DE19931454 | 1999-07-08 | ||
DE19932229 | 1999-07-09 | ||
DE19932182 | 1999-07-09 | ||
DE19932128 | 1999-07-09 | ||
DE19932122 | 1999-07-09 | ||
DE19932125 | 1999-07-09 | ||
DE19932212 | 1999-07-09 | ||
DE19932190 | 1999-07-09 | ||
DE19932228 | 1999-07-09 | ||
DE19932180 | 1999-07-09 | ||
DE19932227 | 1999-07-09 | ||
DE19932191 | 1999-07-09 | ||
DE19932230 | 1999-07-09 | ||
DE19932124 | 1999-07-09 | ||
DE19932209 | 1999-07-09 | ||
DE19933005 | 1999-07-14 | ||
DE19933006 | 1999-07-14 | ||
DE19932927 | 1999-07-14 | ||
DE19940764 | 1999-08-27 | ||
DE19940830 | 1999-08-27 | ||
DE19940832 | 1999-08-27 | ||
DE19940831 | 1999-08-27 | ||
DE19940765 | 1999-08-27 | ||
DE19940766 | 1999-08-27 | ||
DE19940833 | 1999-08-27 | ||
DE19941378 | 1999-08-31 | ||
DE19941379 | 1999-08-31 | ||
DE19941395 | 1999-08-31 | ||
DE19942077 | 1999-09-03 | ||
DE19942079 | 1999-09-03 | ||
DE19942078 | 1999-09-03 | ||
DE19942088 | 1999-09-03 |
Publications (2)
Publication Number | Publication Date |
---|---|
TR200607443T1 true TR200607443T1 (en) | 2007-04-24 |
TR200607443T2 TR200607443T2 (en) | 2007-10-22 |
Family
ID=27586932
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2006/07443T TR200607443T2 (en) | 1999-06-25 | 2000-06-23 | Proteins encoding corynebacterium glutamicum in membrane synthesis and membrane transplantation |
TR2001/03708T TR200103708T2 (en) | 1999-06-25 | 2000-06-23 | Proteins encoding corynemacterium glutamicum within membrane synthesis and membrane transplant |
TR2006/07442T TR200607442T2 (en) | 1999-06-25 | 2000-06-23 | Proteins encoding corynemacterium glutamicum in membrane synthesis and membrane transplantation. |
TR2006/07441T TR200607441T2 (en) | 1999-06-25 | 2000-06-23 | Proteins encoding corynemacterium glutamicum in membrane synthesis and membrane transplantation. |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2001/03708T TR200103708T2 (en) | 1999-06-25 | 2000-06-23 | Proteins encoding corynemacterium glutamicum within membrane synthesis and membrane transplant |
TR2006/07442T TR200607442T2 (en) | 1999-06-25 | 2000-06-23 | Proteins encoding corynemacterium glutamicum in membrane synthesis and membrane transplantation. |
TR2006/07441T TR200607441T2 (en) | 1999-06-25 | 2000-06-23 | Proteins encoding corynemacterium glutamicum in membrane synthesis and membrane transplantation. |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1255839A2 (en) |
JP (2) | JP2004513603A (en) |
KR (3) | KR20070087032A (en) |
CA (1) | CA2380863A1 (en) |
CZ (1) | CZ20014660A3 (en) |
ES (1) | ES2177476T1 (en) |
MX (1) | MXPA01012845A (en) |
SK (1) | SK18912001A3 (en) |
TR (4) | TR200607443T2 (en) |
WO (1) | WO2001000805A2 (en) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6893852B1 (en) | 1999-07-02 | 2005-05-17 | Ajinomoto Co., Inc. | Dna encoding sucrose pts enzyme II |
DE19941478A1 (en) | 1999-09-01 | 2001-03-08 | Degussa | New nucleotide sequences coding for the thrE gene and process for the fermentative production of L-threonine with coryneform bacteria |
DE10021831A1 (en) * | 2000-05-04 | 2001-11-08 | Degussa | New nucleotide sequences coding for the fadD15 gene |
DE10021832A1 (en) * | 2000-05-04 | 2001-11-08 | Degussa | New nucleotide sequences coding for the cma gene |
US6562607B2 (en) | 2000-05-04 | 2003-05-13 | Degussa-Huls Aktiengesellschaft | Nucleotide sequences coding for the cls gene |
DE10021829A1 (en) * | 2000-05-04 | 2001-11-08 | Degussa | New nucleotide sequences coding for the pgsA2 gene |
DE10021828A1 (en) * | 2000-05-04 | 2001-11-08 | Degussa | New nucleotide sequences coding for the cdsA gene |
DE10021826A1 (en) * | 2000-05-04 | 2001-11-08 | Degussa | New mutant coryneform bacterium, useful for production of amino acids, especially glutamate, has increased activity of cardiolipin synthase |
DE10023400A1 (en) | 2000-05-12 | 2001-11-15 | Degussa | New acyl-carrier protein gene, acp, from coryneform bacteria, useful for increasing fermentative production of amino acids, especially lysine |
US20020081673A1 (en) | 2000-06-02 | 2002-06-27 | Bettina Mockel | Novel nucleotide sequences coding for the glbO gene |
DE10032173A1 (en) * | 2000-07-01 | 2002-01-17 | Degussa | New nucleotide sequences encoding the plsC gene |
DE10045579A1 (en) * | 2000-09-15 | 2002-04-11 | Degussa | New nucleotide sequences coding for the atr61 gene |
AU2001293731A1 (en) * | 2000-09-19 | 2002-04-02 | Degussa A.G. | Nucleotide sequences coding for the dcta gene |
DE10057801A1 (en) * | 2000-11-22 | 2002-05-23 | Degussa | New polynucleotide encoding the CysQ transporter of coryneform bacteria, useful, when over expressed, for increasing fermentative production of amino acids |
DE10154270A1 (en) | 2001-11-05 | 2003-05-15 | Basf Ag | Genes that code for carbon metabolism and energy production proteins |
DE10154179A1 (en) * | 2001-11-05 | 2003-05-08 | Basf Ag | Genes coding for membrane synthesis and membrane transport proteins |
DE10163167A1 (en) * | 2001-12-21 | 2003-07-03 | Degussa | Process for the fermentative production of L-amino acids and use of coryneform bacteria |
WO2003097798A2 (en) * | 2002-05-14 | 2003-11-27 | Martek Biosciences Corporation | Carotene synthase gene and uses therefor |
US7468262B2 (en) | 2003-05-16 | 2008-12-23 | Ajinomoto Co., Inc. | Polynucleotides encoding useful polypeptides in corynebacterium glutamicum ssp. lactofermentum |
DE102004009454A1 (en) * | 2004-02-27 | 2005-09-15 | Degussa Ag | Fermentative production of L-amino acids, especially methionine, useful e.g. in animal nutrition, by culturing bacteria in which components of the methionine uptake system are suppressed |
WO2008126896A1 (en) * | 2007-04-10 | 2008-10-23 | Ajinomoto Co., Inc. | Method for production of organic acid |
KR101694850B1 (en) * | 2014-10-08 | 2017-01-10 | 씨제이제일제당 주식회사 | Microorganism producing L-glutamine and process for preparing L-glutamine using the same |
MX2019005420A (en) * | 2017-04-04 | 2019-11-18 | Nnb Nutrition Usa Llc | Preparation of (r)-3-hydroxybutyric acid or its salts by one-step fermentation. |
KR101968317B1 (en) | 2018-02-23 | 2019-04-11 | 씨제이제일제당 주식회사 | Novel L-tryptophan export protein and the method of producing L-tryptophan usingthe same |
WO2019228937A1 (en) * | 2018-05-28 | 2019-12-05 | Universitaet Des Saarlandes | Means and methods for the production of glutarate |
EP3670525A1 (en) | 2018-12-18 | 2020-06-24 | Evonik Operations GmbH | Method for the fermentative production of l-lysine using c. glutamicum strains with a mutated kup transporter |
CN112143676B (en) * | 2020-09-21 | 2022-03-18 | 山西大学 | Bacillus halodurans for producing alkaline protease and method and application of bacillus halodurans for producing alkaline protease |
CN114763372A (en) * | 2021-01-13 | 2022-07-19 | 中国科学院天津工业生物技术研究所 | Protein with L-proline efflux function and application thereof |
KR102261851B1 (en) * | 2021-01-15 | 2021-06-04 | 씨제이제일제당 (주) | Novel ABC transporter ATP-binding protein variant and a method for producing L-lysine using the same |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1196453B (en) * | 1986-07-04 | 1988-11-16 | Sclavo Spa | CORYNEBACTERIUM DIPHTHERIAE DNA ELEMENT WITH TYPICAL PROPERTIES OF AN IS INSERTION ELEMENT |
US6649379B1 (en) * | 1987-06-12 | 2003-11-18 | Massachusetts Institute Of Technology | Method and deregulated enzyme for threonine production |
JP2967996B2 (en) * | 1989-06-06 | 1999-10-25 | 協和醗酵工業株式会社 | Method for producing L-tryptophan |
MY113040A (en) * | 1994-02-24 | 2001-11-30 | Ajinomoto Kk | Novel gene derived from coryneform bacteria and use thereof |
US6737248B2 (en) * | 1996-01-05 | 2004-05-18 | Human Genome Sciences, Inc. | Staphylococcus aureus polynucleotides and sequences |
-
2000
- 2000-06-23 CZ CZ20014660A patent/CZ20014660A3/en unknown
- 2000-06-23 MX MXPA01012845A patent/MXPA01012845A/en not_active Application Discontinuation
- 2000-06-23 TR TR2006/07443T patent/TR200607443T2/en unknown
- 2000-06-23 KR KR1020077015871A patent/KR20070087032A/en not_active Application Discontinuation
- 2000-06-23 TR TR2001/03708T patent/TR200103708T2/en unknown
- 2000-06-23 ES ES00939001T patent/ES2177476T1/en active Pending
- 2000-06-23 JP JP2001506799A patent/JP2004513603A/en active Pending
- 2000-06-23 KR KR1020067022650A patent/KR100878332B1/en active IP Right Grant
- 2000-06-23 EP EP00939001A patent/EP1255839A2/en not_active Ceased
- 2000-06-23 TR TR2006/07442T patent/TR200607442T2/en unknown
- 2000-06-23 CA CA002380863A patent/CA2380863A1/en not_active Abandoned
- 2000-06-23 KR KR1020017016590A patent/KR100834989B1/en not_active IP Right Cessation
- 2000-06-23 SK SK1891-2001A patent/SK18912001A3/en not_active Application Discontinuation
- 2000-06-23 WO PCT/IB2000/000926 patent/WO2001000805A2/en active Application Filing
- 2000-06-23 TR TR2006/07441T patent/TR200607441T2/en unknown
-
2006
- 2006-05-11 JP JP2006132306A patent/JP2006271389A/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
ES2177476T1 (en) | 2002-12-16 |
JP2004513603A (en) | 2004-05-13 |
KR100834989B1 (en) | 2008-06-03 |
KR20070087032A (en) | 2007-08-27 |
TR200607441T2 (en) | 2007-02-21 |
EP1255839A2 (en) | 2002-11-13 |
WO2001000805A3 (en) | 2001-10-25 |
JP2006271389A (en) | 2006-10-12 |
KR20060118626A (en) | 2006-11-23 |
CZ20014660A3 (en) | 2002-09-11 |
CA2380863A1 (en) | 2001-01-04 |
KR20030002295A (en) | 2003-01-08 |
TR200607443T2 (en) | 2007-10-22 |
MXPA01012845A (en) | 2002-07-09 |
SK18912001A3 (en) | 2002-10-08 |
TR200103708T2 (en) | 2002-08-21 |
TR200607442T2 (en) | 2007-02-21 |
WO2001000805A2 (en) | 2001-01-04 |
KR100878332B1 (en) | 2009-01-14 |
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