TR200103144T2 - Yeni bileşikler - Google Patents
Yeni bileşiklerInfo
- Publication number
- TR200103144T2 TR200103144T2 TR2001/03144T TR200103144T TR200103144T2 TR 200103144 T2 TR200103144 T2 TR 200103144T2 TR 2001/03144 T TR2001/03144 T TR 2001/03144T TR 200103144 T TR200103144 T TR 200103144T TR 200103144 T2 TR200103144 T2 TR 200103144T2
- Authority
- TR
- Turkey
- Prior art keywords
- compounds
- carboxypeptide
- pharmaceutically acceptable
- new compounds
- salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/132—Amines having two or more amino groups, e.g. spermidine, putrescine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C211/09—Diamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/55—Acids; Esters
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyridine Compounds (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Mevcut bulus (I) formülüne ait bilesiklerle ve bunlarin farmasötik olarak kabul edilen tuzlari ve çözücüleriyle ya da bu tür tuzlarin çözücüleriyle ilgilidir ve söz konusu bilesikler karboksipeptidas U'yu inhibite ettigi için karboksipeptidas U ile iliskili bulunan hastaliklarin önlenmesinde ve tedavi edilebilmesinde kullanilabilmektedir. Öte yanda bulus, bulus bilesiklerinin tedavi amaçli kullanilmasiyla; bu tür yeni bilesiklerin hazirlanmasina yönelik usullerle; en az bir bulus bilesigi ya da bunun farmasötik olarak kabul edilen tuzunu ya da çözüntüsünü etkin bilesen olarak içeren farmasötik bilesimlerle; ve etkin bilesiklerin yukarida belirtilen tibbi kullanima yönelik ilaçlari imalatinda kullanimiyla ilgilidir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9901572A SE9901572D0 (sv) | 1999-05-03 | 1999-05-03 | New compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200103144T2 true TR200103144T2 (tr) | 2004-11-22 |
Family
ID=20415425
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2001/03144T TR200103144T2 (tr) | 1999-05-03 | 2000-05-03 | Yeni bileşikler |
Country Status (23)
Country | Link |
---|---|
US (2) | US7354895B1 (tr) |
EP (1) | EP1180099A1 (tr) |
JP (1) | JP4270759B2 (tr) |
KR (1) | KR20020010631A (tr) |
CN (1) | CN1358187A (tr) |
AR (1) | AR028826A1 (tr) |
AU (1) | AU4447100A (tr) |
BR (1) | BR0010256A (tr) |
CA (1) | CA2371215A1 (tr) |
CZ (1) | CZ20013931A3 (tr) |
EE (1) | EE200100573A (tr) |
HK (1) | HK1042493A1 (tr) |
HU (1) | HUP0202379A3 (tr) |
IL (1) | IL145953A0 (tr) |
IS (1) | IS6141A (tr) |
MX (1) | MXPA01011043A (tr) |
NO (1) | NO20015374L (tr) |
PL (1) | PL356140A1 (tr) |
SE (1) | SE9901572D0 (tr) |
SK (1) | SK15662001A3 (tr) |
TR (1) | TR200103144T2 (tr) |
WO (1) | WO2000066550A1 (tr) |
ZA (2) | ZA200108966B (tr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2202171T3 (es) * | 1999-09-14 | 2004-04-01 | Meiji Seika Kaisha, Ltd. | Derivados del acido fosfonico que poseen actividad inhibidora de la carboxipeptidas b. |
DE60140368D1 (de) * | 2000-08-17 | 2009-12-17 | Pfizer Ltd | Substitutuierte imidazole als tafia inhibitoren |
SE0103272D0 (sv) * | 2001-09-28 | 2001-09-28 | Astrazeneca Ab | Chemical compounds |
US6713496B2 (en) | 2002-01-22 | 2004-03-30 | Pfizer Inc | 3-(imidazolyl)-2-alkoxypropanoic acids |
JP2005516972A (ja) | 2002-01-22 | 2005-06-09 | ファイザー・インク | 血栓疾患の治療のためのtafi−a阻害剤として使用される3−(イミダゾリル)−2−アミノプロピオン酸 |
OA12756A (en) * | 2002-01-22 | 2006-07-03 | Pfizer | 3-(Imidazolyl)-2-alkoxypropanoic acids as tafia inhibitors. |
EP1497300A2 (en) * | 2002-03-21 | 2005-01-19 | Schering Aktiengesellschaft | Plasma carboxypeptidase b inhibitors |
US20110213143A1 (en) | 2008-10-29 | 2011-09-01 | Taisho Pharmaceutical Co., Ltd. | Compound having tafia inhibitory activity |
CR20210463A (es) * | 2019-02-08 | 2021-10-15 | Astrazeneca Ab | Inhibidores de arginasa y métodos de uso de estos |
CN111110837B (zh) * | 2020-01-06 | 2022-11-25 | 中国人民解放军陆军军医大学 | 一种羧肽酶抑制剂在制备预防重症致死性轮状病毒感染药物中的应用 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2516307A (en) * | 1949-01-06 | 1950-07-25 | Gen Mills Inc | Vinyl resins plasticized with cyano esters |
US4560680A (en) * | 1982-03-15 | 1985-12-24 | E. R. Squibb & Sons, Inc. | Aminoalkyl and related substituted phosphinic acid angiotensin converting enzyme inhibitors |
US4849414A (en) * | 1986-06-11 | 1989-07-18 | E. R. Squibb & Sons, Inc. | Substituted aminoalkanoylaminoalkyl phosphonate angiotensin converting enzyme inhibitors |
FR2610951B1 (fr) * | 1987-02-17 | 1989-05-05 | Aerospatiale | Armature tissee pour materiau composite |
IL86951A (en) * | 1987-07-06 | 1996-07-23 | Procter & Gamble Pharma | Methylene phosphonoalkylphosphinates and pharmaceutical preparations containing them |
WO1993011786A1 (en) * | 1991-12-17 | 1993-06-24 | Procter & Gamble Pharmaceuticals, Inc. | Methods for the treatment of osteoporosis using bisphosphonates and parathyroid hormone |
US5550119A (en) * | 1995-03-02 | 1996-08-27 | Ciba-Geigy Corporation | Phosphono substituted tetrazole derivatives as ECE inhibitors |
US5672592A (en) * | 1996-06-17 | 1997-09-30 | Guilford Pharmaceuticals Inc. | Certain phosphonomethyl-pentanedioic acid derivatives thereof |
JP3440305B2 (ja) * | 1997-04-02 | 2003-08-25 | 高砂香料工業株式会社 | 7−(n−置換アミノ)−2−フェニルヘプタン酸 エステル誘導体及び該誘導体の製造方法 |
SK115899A3 (en) | 1997-02-27 | 2000-05-16 | American Cyanamid Co | N-hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors |
SE9901573D0 (sv) * | 1999-05-03 | 1999-05-03 | Astra Ab | New compounds |
AR023819A1 (es) * | 1999-05-03 | 2002-09-04 | Astrazeneca Ab | FORMULACIoN FARMACEUTICA, KIT DE PARTES Y UTILIZACION DE DICHA FORMULACION |
ES2202171T3 (es) * | 1999-09-14 | 2004-04-01 | Meiji Seika Kaisha, Ltd. | Derivados del acido fosfonico que poseen actividad inhibidora de la carboxipeptidas b. |
-
1999
- 1999-05-03 SE SE9901572A patent/SE9901572D0/xx unknown
-
2000
- 2000-04-28 AR ARP000102082A patent/AR028826A1/es not_active Application Discontinuation
- 2000-05-03 KR KR1020017014014A patent/KR20020010631A/ko not_active Application Discontinuation
- 2000-05-03 AU AU44471/00A patent/AU4447100A/en not_active Abandoned
- 2000-05-03 CA CA002371215A patent/CA2371215A1/en not_active Abandoned
- 2000-05-03 SK SK1566-2001A patent/SK15662001A3/sk unknown
- 2000-05-03 WO PCT/SE2000/000846 patent/WO2000066550A1/en not_active Application Discontinuation
- 2000-05-03 US US09/600,660 patent/US7354895B1/en not_active Expired - Fee Related
- 2000-05-03 PL PL00356140A patent/PL356140A1/xx not_active Application Discontinuation
- 2000-05-03 EP EP00925844A patent/EP1180099A1/en not_active Ceased
- 2000-05-03 BR BR0010256-3A patent/BR0010256A/pt not_active Application Discontinuation
- 2000-05-03 JP JP2000615381A patent/JP4270759B2/ja not_active Expired - Fee Related
- 2000-05-03 EE EEP200100573A patent/EE200100573A/xx unknown
- 2000-05-03 MX MXPA01011043A patent/MXPA01011043A/es unknown
- 2000-05-03 CN CN00809484A patent/CN1358187A/zh active Pending
- 2000-05-03 TR TR2001/03144T patent/TR200103144T2/tr unknown
- 2000-05-03 IL IL14595300A patent/IL145953A0/xx unknown
- 2000-05-03 HU HU0202379A patent/HUP0202379A3/hu unknown
- 2000-05-03 CZ CZ20013931A patent/CZ20013931A3/cs unknown
-
2001
- 2001-10-30 ZA ZA200108966A patent/ZA200108966B/en unknown
- 2001-10-30 ZA ZA200108967A patent/ZA200108967B/en unknown
- 2001-11-01 IS IS6141A patent/IS6141A/is unknown
- 2001-11-02 NO NO20015374A patent/NO20015374L/no not_active Application Discontinuation
-
2002
- 2002-06-06 HK HK02104304.1A patent/HK1042493A1/zh unknown
-
2005
- 2005-12-02 US US11/293,060 patent/US7423012B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EE200100573A (et) | 2003-02-17 |
KR20020010631A (ko) | 2002-02-04 |
NO20015374D0 (no) | 2001-11-02 |
JP2002543179A (ja) | 2002-12-17 |
US7423012B2 (en) | 2008-09-09 |
CA2371215A1 (en) | 2000-11-09 |
BR0010256A (pt) | 2002-02-13 |
SE9901572D0 (sv) | 1999-05-03 |
CN1358187A (zh) | 2002-07-10 |
MXPA01011043A (es) | 2002-06-04 |
US7354895B1 (en) | 2008-04-08 |
WO2000066550A1 (en) | 2000-11-09 |
ZA200108967B (en) | 2003-01-30 |
EP1180099A1 (en) | 2002-02-20 |
US20060079484A1 (en) | 2006-04-13 |
ZA200108966B (en) | 2003-01-30 |
HUP0202379A2 (hu) | 2002-12-28 |
CZ20013931A3 (cs) | 2002-04-17 |
PL356140A1 (en) | 2004-06-14 |
WO2000066550A8 (en) | 2001-01-25 |
HK1042493A1 (zh) | 2002-08-16 |
HUP0202379A3 (en) | 2003-04-28 |
AU4447100A (en) | 2000-11-17 |
JP4270759B2 (ja) | 2009-06-03 |
NO20015374L (no) | 2001-11-02 |
IL145953A0 (en) | 2002-11-10 |
IS6141A (is) | 2001-11-01 |
SK15662001A3 (sk) | 2002-09-10 |
AR028826A1 (es) | 2003-05-28 |
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