TR200101901T2 - 5-[{6-(2-Flüorobenzil)oksi-2-naftil}metil]-2,4-Tiyazolidin dion kristalleri - Google Patents
5-[{6-(2-Flüorobenzil)oksi-2-naftil}metil]-2,4-Tiyazolidin dion kristalleriInfo
- Publication number
- TR200101901T2 TR200101901T2 TR2001/01901T TR200101901T TR200101901T2 TR 200101901 T2 TR200101901 T2 TR 200101901T2 TR 2001/01901 T TR2001/01901 T TR 2001/01901T TR 200101901 T TR200101901 T TR 200101901T TR 200101901 T2 TR200101901 T2 TR 200101901T2
- Authority
- TR
- Turkey
- Prior art keywords
- oxy
- naphthyl
- crystals
- methyl
- fluorobenzyl
- Prior art date
Links
- 239000013078 crystal Substances 0.000 title abstract 2
- PKWDZWYVIHVNKS-UHFFFAOYSA-N netoglitazone Chemical compound FC1=CC=CC=C1COC1=CC=C(C=C(CC2C(NC(=O)S2)=O)C=C2)C2=C1 PKWDZWYVIHVNKS-UHFFFAOYSA-N 0.000 title 1
- QMIZALUHELNFDP-UHFFFAOYSA-N FC1=CC=CC=C1COC1=CC=C(C=C(CC2NCSC2)C=C2)C2=C1 Chemical compound FC1=CC=CC=C1COC1=CC=C(C=C(CC2NCSC2)C=C2)C2=C1 QMIZALUHELNFDP-UHFFFAOYSA-N 0.000 abstract 1
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract 1
- 201000001431 Hyperuricemia Diseases 0.000 abstract 1
- 206010033645 Pancreatitis Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000032839 leukemia Diseases 0.000 abstract 1
- 229940126585 therapeutic drug Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Cosmetics (AREA)
- Photoreceptors In Electrophotography (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Mevcut bulus, 5-[{6-(2-flüoro benzil)oksi-2-naftil}metil]-2,4-tiyazolidin dion'un kararli ve yeni A tipi kristallerine iliskin olup, bunlar asagidaki hastaliklarin tedavisine yönelik terapötik ilaçlarda aktif bilesen olarak kullanilmaya uygundur: diyabet ve komplikasyonlari, hiperlipidemi ve komplikasyonlari, hiperürisemi, lösemi ve pankreatit.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP33054698 | 1998-11-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200101901T2 true TR200101901T2 (tr) | 2002-04-22 |
Family
ID=18233859
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2002/02110T TR200202110T2 (tr) | 1998-11-20 | 1999-11-19 | "5-[{6-(2-Flüore benzil) oksi-2-naftil}metil]-2,4-tiyazolidin dion kristalleri" |
TR2002/02109T TR200202109T2 (tr) | 1998-11-20 | 1999-11-19 | 5-[{6-(2-Flüorobenzil)oksi-2-naftil}metil]-2,4-tiyazolidin dion kristalleri |
TR2001/01901T TR200101901T2 (tr) | 1998-11-20 | 1999-11-19 | 5-[{6-(2-Flüorobenzil)oksi-2-naftil}metil]-2,4-Tiyazolidin dion kristalleri |
TR2002/02103T TR200202103T2 (tr) | 1998-11-20 | 1999-11-19 | ''5-[{6-(2-Flüorobenzil)oksi-2-naftil}metil]-2,4-tiyazolidin dion kristalleri'' |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2002/02110T TR200202110T2 (tr) | 1998-11-20 | 1999-11-19 | "5-[{6-(2-Flüore benzil) oksi-2-naftil}metil]-2,4-tiyazolidin dion kristalleri" |
TR2002/02109T TR200202109T2 (tr) | 1998-11-20 | 1999-11-19 | 5-[{6-(2-Flüorobenzil)oksi-2-naftil}metil]-2,4-tiyazolidin dion kristalleri |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2002/02103T TR200202103T2 (tr) | 1998-11-20 | 1999-11-19 | ''5-[{6-(2-Flüorobenzil)oksi-2-naftil}metil]-2,4-tiyazolidin dion kristalleri'' |
Country Status (23)
Country | Link |
---|---|
US (3) | US6541493B1 (tr) |
EP (1) | EP1131310B1 (tr) |
JP (1) | JP3784001B2 (tr) |
KR (1) | KR100652326B1 (tr) |
CN (1) | CN1326449A (tr) |
AT (1) | ATE315552T1 (tr) |
AU (1) | AU1185100A (tr) |
BR (1) | BR9916795A (tr) |
CA (1) | CA2351727C (tr) |
CZ (1) | CZ20011763A3 (tr) |
DE (1) | DE69929476T2 (tr) |
ES (1) | ES2257104T3 (tr) |
HU (1) | HUP0104139A3 (tr) |
ID (1) | ID30064A (tr) |
IL (1) | IL143177A0 (tr) |
NO (1) | NO20012444L (tr) |
NZ (1) | NZ512429A (tr) |
PL (1) | PL348502A1 (tr) |
PT (1) | PT1131310E (tr) |
TR (4) | TR200202110T2 (tr) |
TW (2) | TWI250156B (tr) |
WO (1) | WO2000031055A1 (tr) |
ZA (1) | ZA200104081B (tr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ID30064A (id) * | 1998-11-20 | 2001-11-01 | Mitsibishi Chemical Corp | Kristal-kristal 5[(2-fluorobenzil) oksi-2-naftil) metil]-2, 4-tiazolidinedion |
AU1776701A (en) * | 1999-11-19 | 2001-05-30 | Ortho-Mcneil Pharmaceutical, Inc. | Solid state forms of 5-((6-((2-fluorophenyl)methoxy)-2-naphthalenyl)methyl)-2,4- thiazolidinedione |
CA2442917C (en) * | 2001-04-04 | 2011-02-01 | Ortho-Mcneil Pharmaceutical, Inc. | Combination therapy comprising glucose reabsorption inhibitors and ppar modulators |
WO2007049050A2 (en) * | 2005-10-27 | 2007-05-03 | Heptahelix Ab | Modulators of gpr40 for the treatment of diabetes |
ES2423991T3 (es) * | 2008-02-04 | 2013-09-26 | Pfizer Limited | Forma polimórfica de un derivado de [1,2,4]triazolo[4,3-a]piridina para el tratamiento de enfermedades inflamatorias |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5594016A (en) * | 1992-12-28 | 1997-01-14 | Mitsubishi Chemical Corporation | Naphthalene derivatives |
JP2845743B2 (ja) | 1992-12-28 | 1999-01-13 | 三菱化学株式会社 | 新規なナフタレン誘導体 |
JP4023697B2 (ja) | 1996-11-14 | 2007-12-19 | 三菱化学株式会社 | ナフタレン誘導体の製造方法 |
ID30064A (id) * | 1998-11-20 | 2001-11-01 | Mitsibishi Chemical Corp | Kristal-kristal 5[(2-fluorobenzil) oksi-2-naftil) metil]-2, 4-tiazolidinedion |
-
1999
- 1999-11-19 ID IDW00200101331A patent/ID30064A/id unknown
- 1999-11-19 IL IL14317799A patent/IL143177A0/xx unknown
- 1999-11-19 ES ES99972628T patent/ES2257104T3/es not_active Expired - Lifetime
- 1999-11-19 TR TR2002/02110T patent/TR200202110T2/tr unknown
- 1999-11-19 AT AT99972628T patent/ATE315552T1/de not_active IP Right Cessation
- 1999-11-19 AU AU11851/00A patent/AU1185100A/en not_active Abandoned
- 1999-11-19 CN CN99813380A patent/CN1326449A/zh active Pending
- 1999-11-19 TR TR2002/02109T patent/TR200202109T2/tr unknown
- 1999-11-19 PL PL99348502A patent/PL348502A1/xx unknown
- 1999-11-19 BR BR9916795-6A patent/BR9916795A/pt not_active IP Right Cessation
- 1999-11-19 NZ NZ512429A patent/NZ512429A/en unknown
- 1999-11-19 HU HU0104139A patent/HUP0104139A3/hu unknown
- 1999-11-19 JP JP2000583883A patent/JP3784001B2/ja not_active Expired - Fee Related
- 1999-11-19 WO PCT/JP1999/006492 patent/WO2000031055A1/en active IP Right Grant
- 1999-11-19 US US09/856,295 patent/US6541493B1/en not_active Expired - Fee Related
- 1999-11-19 EP EP99972628A patent/EP1131310B1/en not_active Expired - Lifetime
- 1999-11-19 CA CA002351727A patent/CA2351727C/en not_active Expired - Fee Related
- 1999-11-19 CZ CZ20011763A patent/CZ20011763A3/cs unknown
- 1999-11-19 TR TR2001/01901T patent/TR200101901T2/tr unknown
- 1999-11-19 PT PT99972628T patent/PT1131310E/pt unknown
- 1999-11-19 DE DE69929476T patent/DE69929476T2/de not_active Expired - Fee Related
- 1999-11-19 TR TR2002/02103T patent/TR200202103T2/tr unknown
- 1999-11-19 KR KR1020017006299A patent/KR100652326B1/ko not_active IP Right Cessation
- 1999-11-20 TW TW088120305A patent/TWI250156B/zh not_active IP Right Cessation
- 1999-11-20 TW TW094136910A patent/TWI272944B/zh not_active IP Right Cessation
-
2001
- 2001-05-18 ZA ZA200104081A patent/ZA200104081B/en unknown
- 2001-05-18 NO NO20012444A patent/NO20012444L/no not_active Application Discontinuation
-
2003
- 2003-01-31 US US10/355,160 patent/US20030158241A1/en not_active Abandoned
-
2006
- 2006-02-21 US US11/357,208 patent/US20060149075A1/en not_active Abandoned
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