TR200101803T2 - Sodyum hidrojen değiştiricisi inhibitörlerinin, bir ilacın üretiminde kullanımı - Google Patents
Sodyum hidrojen değiştiricisi inhibitörlerinin, bir ilacın üretiminde kullanımıInfo
- Publication number
- TR200101803T2 TR200101803T2 TR2001/01803T TR200101803T TR200101803T2 TR 200101803 T2 TR200101803 T2 TR 200101803T2 TR 2001/01803 T TR2001/01803 T TR 2001/01803T TR 200101803 T TR200101803 T TR 200101803T TR 200101803 T2 TR200101803 T2 TR 200101803T2
- Authority
- TR
- Turkey
- Prior art keywords
- drug
- manufacture
- sodium hydrogen
- hydrogen exchanger
- inhibitors
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
Abstract
Hücresel sodyum-hidrojen degistiricisinin inhibitörleri yasliliga bagli fonksiyon arizalarinin ve bedensel organlarin islevsizlik yönündeki degisikliklerinin önlenmesi ve ayrica yasliliga bagli hastaliklarin önlenmesi ile yasam kalitesi iyilestirilerek yasam süresinin uzatilmasi amaciyla kullanilmaktadir. Bu türdeki NHE-inhibitörlerinin tipik temsilcileri arasinda kariporid (a) ve aniporid (b) yer almaktadir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19859727A DE19859727A1 (de) | 1998-12-23 | 1998-12-23 | Die Verwendung von Hemmern des Natrium-Wasserstoff-Austauschers zur Herstellung eines Medikaments zur Verhinderung von altersbedingten Organ-Dysfunktionen, altersbedingten Erkrankungen zur Lebensverlängerung |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200101803T2 true TR200101803T2 (tr) | 2001-10-22 |
Family
ID=7892436
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2001/01803T TR200101803T2 (tr) | 1998-12-23 | 1999-12-08 | Sodyum hidrojen değiştiricisi inhibitörlerinin, bir ilacın üretiminde kullanımı |
Country Status (20)
Country | Link |
---|---|
US (1) | US6420430B1 (tr) |
EP (1) | EP1140056A2 (tr) |
JP (1) | JP2002533386A (tr) |
KR (1) | KR20010086152A (tr) |
CN (1) | CN1367689A (tr) |
AR (1) | AR021965A1 (tr) |
AU (1) | AU776761B2 (tr) |
BR (1) | BR9916505A (tr) |
CA (1) | CA2357837A1 (tr) |
CZ (1) | CZ20012309A3 (tr) |
DE (1) | DE19859727A1 (tr) |
HR (1) | HRPK20010470B1 (tr) |
HU (1) | HUP0104652A3 (tr) |
IL (1) | IL143372A0 (tr) |
NO (1) | NO20013145L (tr) |
RU (1) | RU2238721C2 (tr) |
SK (1) | SK9042001A3 (tr) |
TR (1) | TR200101803T2 (tr) |
WO (1) | WO2000038661A2 (tr) |
ZA (1) | ZA200104301B (tr) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6844361B2 (en) * | 2002-02-04 | 2005-01-18 | Aventis Pharma Deutschland Gmbh | Pharmaceutical composition comprising a sodium hydrogen exchange inhibitor and an angiotensin converting enzyme inhibitor |
KR20040083498A (ko) * | 2002-02-04 | 2004-10-02 | 아벤티스 파마 도이칠란트 게엠베하 | 심부전증 및 기타 노화-관련된 기관의 기능장애,노화-관련 질환을 예방하고 생명을 연장하기 위한 ace억제제와 나트륨-수소 교환 억제제 카리포리드와의 배합제제 |
US7375138B2 (en) * | 2002-05-18 | 2008-05-20 | Sanofi-Aventis Deutschland Gmbh | Pentafluorosulfanylbenzoylguanidines, processes for their preparation, their use as medicaments or diagnostic aids, and medicaments comprising them |
FR2840302B1 (fr) * | 2002-06-03 | 2004-07-16 | Aventis Pharma Sa | Derives d'isoindolones, procede de preparation et intermediaire de ce procede a titre de medicaments et compositions pharmaceutiques les renfermant |
US6878748B2 (en) | 2002-06-13 | 2005-04-12 | Aventis Pharma Deutschland Gmbh | Fluorinated cycloalkyl-derivatized benzoylguanidines, process for their preparation, their uses as medicament, and medicament containing them |
EP1646371A4 (en) * | 2003-06-26 | 2010-09-22 | Biotron Ltd | ANTIVIRAL COMPOSITIONS AND METHODS |
US8013240B2 (en) * | 2005-11-02 | 2011-09-06 | The Trustees Of Princeton University | Organic photovoltaic cells utilizing ultrathin sensitizing layer |
US7947897B2 (en) * | 2005-11-02 | 2011-05-24 | The Trustees Of Princeton University | Organic photovoltaic cells utilizing ultrathin sensitizing layer |
US8017863B2 (en) * | 2005-11-02 | 2011-09-13 | The Regents Of The University Of Michigan | Polymer wrapped carbon nanotube near-infrared photoactive devices |
KR101042078B1 (ko) * | 2009-01-13 | 2011-06-16 | 한국항공우주산업 주식회사 | 치공구 제작용 수평 측면 가공 치구 |
CN104103253B (zh) | 2014-07-04 | 2016-08-17 | 京东方科技集团股份有限公司 | 发射电极扫描电路、阵列基板和显示装置 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE147375T1 (de) | 1992-09-22 | 1997-01-15 | Hoechst Ag | Benzoylguanidine, verfahren zu ihrer herstellung, sowie ihre verwendung als antiarrhythmika |
DK0590455T3 (da) * | 1992-09-28 | 2001-01-22 | Hoechst Ag | Antiarrytmiske og cardioprotektive substiuerede 1(2H)-isoquinoliner, fremgangsmåde til deres fremstilling, lægemiddel indeh |
SE508028C2 (sv) * | 1993-05-12 | 1998-08-10 | Moelnlycke Ab | Midjebälte för absorberande plagg |
DE4328352A1 (de) | 1993-08-24 | 1995-03-02 | Hoechst Ag | Substituierte N,N'-Di-benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
US5506065A (en) | 1994-02-25 | 1996-04-09 | Whitehead Alenia Sistemi Subacquei S.P.A. | Electrolyte-activated battery |
DE4430861A1 (de) | 1994-08-31 | 1996-03-07 | Merck Patent Gmbh | Heterocyclyl-benzoylguanidine |
DE19502644A1 (de) | 1995-01-28 | 1996-08-01 | Merck Patent Gmbh | 4-Amino-benzoylguanidin-Derivate |
DE19502895A1 (de) | 1995-01-31 | 1996-08-01 | Merck Patent Gmbh | 4-Mercapto-benzoylguanidin-Derivate |
ATE183498T1 (de) * | 1995-04-18 | 1999-09-15 | Hoechst Ag | Substituierte indenoylguanidines mit antiarrhythmischer und cardioprotektiver wirkung |
EP0765867A1 (de) | 1995-09-27 | 1997-04-02 | Hoechst Aktiengesellschaft | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Antiarrhytmika oder Diagnostikum sowie sie enthaltendes Medikament |
DE19542306A1 (de) | 1995-11-14 | 1997-05-15 | Hoechst Ag | Sulfonylamino-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
DE19621319A1 (de) | 1996-05-28 | 1997-12-04 | Hoechst Ag | Bis-ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
DE19622222A1 (de) * | 1996-06-03 | 1997-12-04 | Hoechst Ag | Verwendung von Inhibitoren des zellulären Na·+·/H·+·-Exchangers (NHE) zur Herstellung eines Medikament zur Normalisierung der Serumlipide |
JP2002502414A (ja) * | 1997-06-02 | 2002-01-22 | 藤沢薬品工業株式会社 | 細胞中のNa▲上+▼/H▲上+▼交換の阻害剤としてのグアニジン誘導体 |
DE19734693A1 (de) * | 1997-08-11 | 1998-01-22 | Hoechst Marion Roussel De Gmbh | Verwendung von Cariporide als Inhibitor des zellulären NA+/H+-Exchangers (NHE) zur Herstellung eines Medikaments zur Behandlung von cardialen und nichtcardialen Krankheiten |
US6011059A (en) * | 1997-12-24 | 2000-01-04 | Bristol-Myers Squibb Company | Acyl guanidine sodium/proton exchange inhibitors and method |
CA2260499A1 (en) * | 1998-01-29 | 1999-07-29 | Sumitomo Pharmaceuticals Company Limited | Pharmaceutical compositions for the treatment of ischemic brain damage |
-
1998
- 1998-12-23 DE DE19859727A patent/DE19859727A1/de not_active Withdrawn
-
1999
- 1999-12-08 CN CN99815044A patent/CN1367689A/zh active Pending
- 1999-12-08 KR KR1020017008052A patent/KR20010086152A/ko not_active Application Discontinuation
- 1999-12-08 IL IL14337299A patent/IL143372A0/xx unknown
- 1999-12-08 HU HU0104652A patent/HUP0104652A3/hu unknown
- 1999-12-08 TR TR2001/01803T patent/TR200101803T2/tr unknown
- 1999-12-08 AU AU16576/00A patent/AU776761B2/en not_active Ceased
- 1999-12-08 WO PCT/EP1999/009621 patent/WO2000038661A2/de not_active Application Discontinuation
- 1999-12-08 RU RU2001120358A patent/RU2238721C2/ru not_active IP Right Cessation
- 1999-12-08 JP JP2000590615A patent/JP2002533386A/ja not_active Withdrawn
- 1999-12-08 BR BR9916505-8A patent/BR9916505A/pt not_active IP Right Cessation
- 1999-12-08 CA CA002357837A patent/CA2357837A1/en not_active Abandoned
- 1999-12-08 CZ CZ20012309A patent/CZ20012309A3/cs unknown
- 1999-12-08 EP EP99959387A patent/EP1140056A2/de not_active Ceased
- 1999-12-08 SK SK904-2001A patent/SK9042001A3/sk unknown
- 1999-12-21 AR ARP990106639A patent/AR021965A1/es unknown
- 1999-12-22 US US09/469,299 patent/US6420430B1/en not_active Expired - Fee Related
-
2001
- 2001-05-25 ZA ZA200104301A patent/ZA200104301B/xx unknown
- 2001-06-20 HR HR20010470A patent/HRPK20010470B1/xx not_active IP Right Cessation
- 2001-06-22 NO NO20013145A patent/NO20013145L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DE19859727A1 (de) | 2000-06-29 |
SK9042001A3 (en) | 2001-12-03 |
HRP20010470A2 (en) | 2002-06-30 |
AU776761B2 (en) | 2004-09-23 |
WO2000038661A2 (de) | 2000-07-06 |
NO20013145D0 (no) | 2001-06-22 |
JP2002533386A (ja) | 2002-10-08 |
CA2357837A1 (en) | 2000-07-06 |
IL143372A0 (en) | 2002-04-21 |
US6420430B1 (en) | 2002-07-16 |
RU2238721C2 (ru) | 2004-10-27 |
AU1657600A (en) | 2000-07-31 |
WO2000038661A3 (de) | 2000-11-09 |
HUP0104652A3 (en) | 2002-09-30 |
RU2001120358A (ru) | 2005-12-10 |
NO20013145L (no) | 2001-08-22 |
HRPK20010470B1 (en) | 2003-10-31 |
CZ20012309A3 (cs) | 2001-09-12 |
EP1140056A2 (de) | 2001-10-10 |
ZA200104301B (en) | 2003-02-20 |
KR20010086152A (ko) | 2001-09-08 |
HUP0104652A2 (hu) | 2002-03-28 |
BR9916505A (pt) | 2001-11-20 |
AR021965A1 (es) | 2002-09-04 |
CN1367689A (zh) | 2002-09-04 |
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