TR200100462T2 - Muskarinik agonistleri ve antagonistleri - Google Patents
Muskarinik agonistleri ve antagonistleriInfo
- Publication number
- TR200100462T2 TR200100462T2 TR2001/00462T TR200100462T TR200100462T2 TR 200100462 T2 TR200100462 T2 TR 200100462T2 TR 2001/00462 T TR2001/00462 T TR 2001/00462T TR 200100462 T TR200100462 T TR 200100462T TR 200100462 T2 TR200100462 T2 TR 200100462T2
- Authority
- TR
- Turkey
- Prior art keywords
- antagonists
- muscarinic agonists
- compounds
- muscarinic
- agonists
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Bu bulus, agrinin iyilestirilmesinde yararli olan yeni bilesikler ve bunlarin farmasötik bilesimlerini temin etmektedir. Bu bulusun bilesikleri azaadamantanlar, azanoradamantanlar ve azahomoadamantanlardir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9697798P | 1998-08-18 | 1998-08-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR200100462T2 true TR200100462T2 (tr) | 2001-09-21 |
Family
ID=22260061
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2001/00462T TR200100462T2 (tr) | 1998-08-18 | 1999-08-16 | Muskarinik agonistleri ve antagonistleri |
Country Status (30)
Country | Link |
---|---|
US (5) | US6093724A (tr) |
EP (1) | EP1112272B1 (tr) |
JP (1) | JP2002523416A (tr) |
KR (1) | KR20010072784A (tr) |
CN (1) | CN1312812A (tr) |
AR (1) | AR020199A1 (tr) |
AT (1) | ATE227724T1 (tr) |
AU (1) | AU750566B2 (tr) |
BG (1) | BG105256A (tr) |
BR (1) | BR9913072A (tr) |
CA (1) | CA2340946A1 (tr) |
CO (1) | CO5130018A1 (tr) |
DE (1) | DE69903961T2 (tr) |
EE (1) | EE200100096A (tr) |
ES (1) | ES2191455T3 (tr) |
HK (1) | HK1038918A1 (tr) |
HU (1) | HUP0103203A3 (tr) |
ID (1) | ID27544A (tr) |
IL (1) | IL141050A0 (tr) |
IS (1) | IS5827A (tr) |
NO (1) | NO20010804L (tr) |
NZ (1) | NZ509762A (tr) |
PE (1) | PE20000988A1 (tr) |
PL (1) | PL346247A1 (tr) |
RU (1) | RU2219179C2 (tr) |
SK (1) | SK1892001A3 (tr) |
TR (1) | TR200100462T2 (tr) |
WO (1) | WO2000011001A1 (tr) |
YU (1) | YU13301A (tr) |
ZA (1) | ZA200100978B (tr) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SK4642003A3 (en) * | 2000-10-19 | 2004-05-04 | Pfizer Prod Inc | Bridged piperazine derivatives |
GB0117950D0 (en) * | 2001-02-16 | 2001-09-19 | Aventis Pharma Inc | Novel heterocyclic urea derivatives andd their use as dopamine D3 receptor ligands |
WO2002094827A1 (en) * | 2001-05-23 | 2002-11-28 | Neurosearch A/S | Fused tropane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
US20030064979A1 (en) * | 2001-06-29 | 2003-04-03 | Hansen Thomas Kruse | Method of inhibiting PTP 1B and /or T-cell PTP and/or other PTPases with an Asp residue at position 48 |
US6828328B1 (en) * | 2002-03-01 | 2004-12-07 | Ucb S.A. | Analgesic combination of muscarinic agonists |
US7897766B2 (en) * | 2005-09-23 | 2011-03-01 | Abbott Laboratories | Amino-aza-adamantane derivatives and methods of use |
US8314119B2 (en) * | 2006-11-06 | 2012-11-20 | Abbvie Inc. | Azaadamantane derivatives and methods of use |
US8076350B2 (en) | 2006-12-22 | 2011-12-13 | Abbott Laboratories | Spirocyclic azaadamantane derivatives and methods of use |
EP2069346B1 (en) * | 2007-03-23 | 2011-12-21 | Abbott Laboratories | Acetamide and carboxamide derivatives of azaadamantane and methods of use thereof |
CA2679876A1 (en) * | 2007-03-23 | 2008-10-02 | Abbott Laboratories | 4-substituted azaadamantane derivatives and methods of use thereof |
RU2549551C2 (ru) * | 2009-06-19 | 2015-04-27 | Эббви Инк. | Производные диазагомоадамантана и способы их применения |
US10265311B2 (en) | 2009-07-22 | 2019-04-23 | PureTech Health LLC | Methods and compositions for treatment of disorders ameliorated by muscarinic receptor activation |
EP3646870A1 (en) | 2009-07-22 | 2020-05-06 | Puretech Health LLC | Methods and compositions for treatment of disorders ameliorated by muscarinic receptor activation |
AR081626A1 (es) | 2010-04-23 | 2012-10-10 | Cytokinetics Inc | Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos |
US9133123B2 (en) | 2010-04-23 | 2015-09-15 | Cytokinetics, Inc. | Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use |
AR081331A1 (es) | 2010-04-23 | 2012-08-08 | Cytokinetics Inc | Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos |
RU2579121C2 (ru) * | 2010-09-23 | 2016-03-27 | Эббви Бахамаз Лтд. | Моногидрат производного азаадамантана |
US8759380B2 (en) | 2011-04-22 | 2014-06-24 | Cytokinetics, Inc. | Certain heterocycles, compositions thereof, and methods for their use |
WO2019126559A1 (en) | 2017-12-20 | 2019-06-27 | Vanderbilt University | Antagonists of the muscarinic acetylcholine receptor m4 |
NZ773719A (en) | 2018-09-28 | 2022-07-29 | Karuna Therapeutics Inc | Compositions and methods for treating disorders ameliorated by muscarinic receptor activation |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4739074A (en) * | 1986-01-22 | 1988-04-19 | Pennwalt Corporation | Adamantane spiro-pyrrolidine derivatives |
IL88156A (en) * | 1987-11-13 | 1997-02-18 | Novo Nordisk As | Azacyclic compounds their preparation and pharmaceutical compositions containing them |
US5527813A (en) * | 1990-08-21 | 1996-06-18 | Novo Nordisk A/S | Heterocyclic compounds and their preparation and use |
EP0563036A1 (en) * | 1990-12-21 | 1993-10-06 | Merck Sharp & Dohme Ltd. | 4-azatricyclo 2.2.1.0?2,6 ]heptanes and pharmaceutical compositions |
US5955470A (en) * | 1991-06-11 | 1999-09-21 | Merrell Pharmaceuticals, Inc. | Derivatives of amide analogs of certain methano bridged quinolizines |
US5641791A (en) * | 1991-08-13 | 1997-06-24 | Novo Nordisk A.S | Heterocyclic compounds and their preparation and use |
ATE224392T1 (de) * | 1995-11-02 | 2002-10-15 | Neurosearch As | Kondensierte tropanderivate als neurotransmitter- reuptake-inhibitoren |
US5914338A (en) * | 1996-04-02 | 1999-06-22 | Novo Nordisk | Heterocyclic compounds and their preparation and use |
US5986100A (en) * | 1998-04-02 | 1999-11-16 | Crooks; Peter Anthony | Pharmaceutical compositions and methods for use |
US6057446A (en) * | 1998-04-02 | 2000-05-02 | Crooks; Peter Anthony | Certain 1-aza-tricyclo [3.3.1-13,7 ] decane compounds |
US5952339A (en) * | 1998-04-02 | 1999-09-14 | Bencherif; Merouane | Pharmaceutical compositions and methods of using nicotinic antagonists for treating a condition or disorder characterized by alteration in normal neurotransmitter release |
-
1999
- 1999-08-16 YU YU13301A patent/YU13301A/sh unknown
- 1999-08-16 RU RU2001107139/04A patent/RU2219179C2/ru not_active IP Right Cessation
- 1999-08-16 ES ES99945064T patent/ES2191455T3/es not_active Expired - Lifetime
- 1999-08-16 TR TR2001/00462T patent/TR200100462T2/tr unknown
- 1999-08-16 ID IDW20010377A patent/ID27544A/id unknown
- 1999-08-16 CN CN99809775A patent/CN1312812A/zh active Pending
- 1999-08-16 NZ NZ509762A patent/NZ509762A/xx unknown
- 1999-08-16 WO PCT/US1999/018570 patent/WO2000011001A1/en not_active Application Discontinuation
- 1999-08-16 HU HU0103203A patent/HUP0103203A3/hu unknown
- 1999-08-16 EE EEP200100096A patent/EE200100096A/xx unknown
- 1999-08-16 PL PL99346247A patent/PL346247A1/xx not_active Application Discontinuation
- 1999-08-16 JP JP2000566274A patent/JP2002523416A/ja active Pending
- 1999-08-16 IL IL14105099A patent/IL141050A0/xx unknown
- 1999-08-16 DE DE69903961T patent/DE69903961T2/de not_active Expired - Fee Related
- 1999-08-16 AT AT99945064T patent/ATE227724T1/de not_active IP Right Cessation
- 1999-08-16 SK SK189-2001A patent/SK1892001A3/sk unknown
- 1999-08-16 US US09/375,149 patent/US6093724A/en not_active Expired - Fee Related
- 1999-08-16 CA CA002340946A patent/CA2340946A1/en not_active Abandoned
- 1999-08-16 KR KR1020017002128A patent/KR20010072784A/ko not_active Application Discontinuation
- 1999-08-16 AU AU57758/99A patent/AU750566B2/en not_active Ceased
- 1999-08-16 EP EP99945064A patent/EP1112272B1/en not_active Expired - Lifetime
- 1999-08-16 BR BR9913072-6A patent/BR9913072A/pt not_active IP Right Cessation
- 1999-08-17 AR ARP990104100A patent/AR020199A1/es unknown
- 1999-08-18 CO CO99052330A patent/CO5130018A1/es unknown
- 1999-08-18 PE PE1999000838A patent/PE20000988A1/es not_active Application Discontinuation
-
2000
- 2000-05-09 US US09/567,785 patent/US6251916B1/en not_active Expired - Fee Related
- 2000-10-17 US US09/690,494 patent/US6323194B1/en not_active Expired - Fee Related
-
2001
- 2001-01-26 IS IS5827A patent/IS5827A/is unknown
- 2001-02-05 ZA ZA200100978A patent/ZA200100978B/xx unknown
- 2001-02-14 BG BG105256A patent/BG105256A/xx unknown
- 2001-02-16 NO NO20010804A patent/NO20010804L/no not_active Application Discontinuation
- 2001-10-05 US US09/972,415 patent/US6423842B1/en not_active Expired - Fee Related
-
2002
- 2002-01-18 HK HK02100409.3A patent/HK1038918A1/zh unknown
- 2002-03-27 US US10/108,046 patent/US6555550B1/en not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TR200100462T2 (tr) | Muskarinik agonistleri ve antagonistleri | |
TR200102029T2 (tr) | 1-Heterosiklil ikameli diarilaminler. | |
TR200001218T2 (tr) | İkameli karboksamidotiazoller, bunların üretimi ve bunları içeren farmasötik bileşimler. | |
DE60205234D1 (de) | 1,2,3,4-tetrahydroisochinolin-derivate als urotensin ii rezeptor-antagonisten | |
TR200100267T2 (tr) | İkameli anilid bileşimleri ve yöntemler. | |
TR200101412T2 (tr) | Yeni bileşikler. | |
PT1274687E (pt) | Derivados de 1,2,3,4-tetra-hidroisoquinolina | |
ATE416772T1 (de) | Biphenylsulfonamide als zweifach aktive rezeptor antagonisten von angiotensin und endothelin | |
SE9802729D0 (sv) | Novel Compounds | |
DE50306232D1 (de) | Ampholytisches copolymer und dessen verwendung | |
ATE383169T1 (de) | Komponente und zusammensetzungen zur verabreichung von wirkstoffen | |
ATE253063T1 (de) | 5-ht1f-agonisten | |
SE9702773D0 (sv) | Novel compounds | |
TR200002896T2 (tr) | Kalsilitik Bileşimler | |
TR200000152T2 (tr) | Yeni bileşikler. | |
TR200200359T2 (tr) | Cgrp Antagonist'lerinin ve cgrp-release (Gevşeme)-Engelleyici Menopoza Bağlı Deri Kızarıklıklarında Kullanılması | |
TR200101756T2 (tr) | Protein kinaz inhibitörleri olarak 4,5-pirazinoksindoller. | |
SE9802937D0 (sv) | Novel compounds | |
TR200102041T2 (tr) | Progesteron reseptör bağlama aktif maddeleri olarak ikameli 2-arilimino heterosaykıllar | |
TR200101493T2 (tr) | Eletriptan hidrobromid monohidrat | |
NO20002408D0 (no) | 5-HT1F antagonister | |
EA200400670A1 (ru) | Фармацевтические композиции, содержащие 3,4-пропинопергидропурины, и их применение для блокирования нейронной передачи | |
TR199800152T1 (tr) | Endotelin Reseptör Antagonistleri | |
TR199901380A2 (tr) | Di-ya da triazo-spiro[4,5] dekan türevleri | |
ATE305517T1 (de) | Neurotrypsin |