TR199903192T2 - Eritropoetin, degistirilmis hemoglobin içeren farmasotik kombine müstahzarlar. - Google Patents
Eritropoetin, degistirilmis hemoglobin içeren farmasotik kombine müstahzarlar.Info
- Publication number
- TR199903192T2 TR199903192T2 TR1999/03192T TR9903192T TR199903192T2 TR 199903192 T2 TR199903192 T2 TR 199903192T2 TR 1999/03192 T TR1999/03192 T TR 1999/03192T TR 9903192 T TR9903192 T TR 9903192T TR 199903192 T2 TR199903192 T2 TR 199903192T2
- Authority
- TR
- Turkey
- Prior art keywords
- preparations containing
- erythropoietin
- modified hemoglobin
- combined preparations
- containing erythropoietin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/41—Porphyrin- or corrin-ring-containing peptides
- A61K38/42—Haemoglobins; Myoglobins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Bulus eritropoetin müstahzarlari ve bir veya daha fazla sayida degistirilmis hemoglobin içeren farmasotik kombine müstahzarlar ile ilgilidir. Kombine müstahzarlar özellikle görünür anemi tedavisinde kullanilir. Eldeki bulusun konusu a) etken maddenin 3.000 ile 7.000 U arasinda tek doz halinde verilmesi için uygun olan eritropoetin müstahzarinin bireysel sunus sekillerini ve b) bir veya daha fazla sayida degistirilmis hemoglobinin 50-100 ml'sini kapsayan farmasotik kombine müstahzar ile ilgili olup eritropoetin müstahzari ve degistirilmis hemoglobin ya ayri ayri ya da birlikte bir bütün olusturacak sekilde sunulabilirler.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97110168A EP0885613A1 (de) | 1997-06-21 | 1997-06-21 | Verwendung von modifizierten Hämoglobinen zur Behandlung von Anämien und Kombinationspräparate umfassend Erythropoietin und modifiziertes Hämoglobin |
Publications (1)
Publication Number | Publication Date |
---|---|
TR199903192T2 true TR199903192T2 (tr) | 2000-05-22 |
Family
ID=8226937
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR1999/03192T TR199903192T2 (tr) | 1997-06-21 | 1998-06-03 | Eritropoetin, degistirilmis hemoglobin içeren farmasotik kombine müstahzarlar. |
Country Status (15)
Country | Link |
---|---|
US (3) | US6440932B1 (tr) |
EP (2) | EP0885613A1 (tr) |
JP (3) | JP2002504913A (tr) |
KR (1) | KR100519904B1 (tr) |
CN (1) | CN1185010C (tr) |
AT (1) | ATE272405T1 (tr) |
AU (1) | AU743475B2 (tr) |
BR (1) | BR9810267A (tr) |
CA (1) | CA2294448C (tr) |
DE (1) | DE59811768D1 (tr) |
DK (1) | DK0996462T3 (tr) |
ES (1) | ES2226151T3 (tr) |
PT (1) | PT996462E (tr) |
TR (1) | TR199903192T2 (tr) |
WO (1) | WO1998058660A1 (tr) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ337465A (en) * | 1997-03-18 | 2002-04-26 | Roche Diagnostics Gmbh | Pharmaceutical containing erythropoietin and iron preparations for treating haemodialysis patients or anaemias |
US7345019B1 (en) * | 1999-04-13 | 2008-03-18 | The Kenneth S. Warren Institute, Inc. | Modulation of excitable tissue function by peripherally administered erythropoietin |
PT1311285E (pt) * | 2000-05-15 | 2005-06-30 | Hoffmann La Roche | Composicao farmaceutica liquida contendo um derivado de eritropoietina |
BR0116381A (pt) | 2000-12-20 | 2004-02-25 | Hoffmann La Roche | Conjugado, composição farmacêutica que compreende o mesmo e sua utilização, processo para o tratamento profilático e/ou terapêutico de distúrbios, processo para a preparação de um conjugado, compostos e glicoproteìnas de eritropoetina |
US20030072737A1 (en) | 2000-12-29 | 2003-04-17 | Michael Brines | Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs |
US7767643B2 (en) | 2000-12-29 | 2010-08-03 | The Kenneth S. Warren Institute, Inc. | Protection, restoration, and enhancement of erythropoietin-responsive cells, tissues and organs |
DE10215315A1 (de) * | 2002-04-05 | 2003-11-20 | Aventis Behring Gmbh Intellect | Human-Transferrin zur Behandlung der Anaemia of Chronic Disease (ACD) und des funktionellen Eisenmangels |
US7459435B2 (en) * | 2002-08-29 | 2008-12-02 | Hoffmann-La Roche Inc. | Treatment of disturbances of iron distribution |
US7459436B2 (en) * | 2002-11-22 | 2008-12-02 | Hoffmann-La Roche Inc. | Treatment of disturbances of iron distribution |
EA010650B1 (ru) | 2003-09-29 | 2008-10-30 | Уоррен Фармасьютикалз, Инк. | Защищающие ткань цитокины для лечения и профилактики сепсиса и образования спаек |
US7772182B2 (en) * | 2004-08-05 | 2010-08-10 | Alza Corporation | Stable suspension formulations of erythropoietin receptor agonists |
JP5723528B2 (ja) | 2006-08-04 | 2015-05-27 | プロロング ファーマシューティカルズ エルエルシー | 修飾されたエリスロポエチン |
CL2008002054A1 (es) | 2007-07-17 | 2009-05-29 | Hoffmann La Roche | Metodo para la regeneracion de una columna de cromatografia de intercambio cationico despues de la elusion de eritropoyetina monopeguilada y metodo para obtener una eritropoyetina monopeguilada, incorporando el metodo de regeneracion de la columna de intercambio cationico. |
CL2008002053A1 (es) | 2007-07-17 | 2009-05-22 | Hoffmann La Roche | Metodo para la purificacion de una eritropoyetina monopeguilada (epompeg) que consiste en proporcionar una solucion que contiene eritropoyetina mono, poli y no peguilada y hacerla pasar por dos pasos de cromatografia de intercambio cationico y metodo para producir epo mpeg que incluye metodo de purificacion. |
SI3380487T1 (sl) | 2015-11-23 | 2020-11-30 | Bristol-Myers Squibb Company | Sistemi dodatkov za uporabo pri pegilaciji proteinov |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL77081A (en) | 1984-12-04 | 1999-10-28 | Genetics Inst | AND sequence encoding human erythropoietin, a process for its preparation and a pharmacological preparation of human erythropoietin |
US4826811A (en) * | 1986-06-20 | 1989-05-02 | Northfield Laboratories, Inc. | Acellular red blood cell substitute |
JP2858752B2 (ja) * | 1987-04-10 | 1999-02-17 | オーソ・フアーマシユーチカル・コーポレーシヨン | 正常な哺乳動物のヘマトクリツト値の増大方法 |
JPH03112934A (ja) * | 1989-09-27 | 1991-05-14 | Mitsubishi Kasei Corp | 圧縮成型可能な粉体組成物 |
US5631219A (en) * | 1994-03-08 | 1997-05-20 | Somatogen, Inc. | Method of stimulating hematopoiesis with hemoglobin |
AU4018695A (en) * | 1994-11-17 | 1996-06-17 | Baxter International Inc. | Hemoglobin therapy in hemodialysis |
DE19535571A1 (de) | 1995-09-14 | 1997-03-20 | Boehringer Mannheim Gmbh | Pharmazeutische Kombinationspräparate und deren Verwendung zur Behandlung von Hämodialysepatienten |
EP0939644B1 (en) | 1996-08-27 | 2004-01-14 | Hemosol Inc. | Enhanced stimulation of erythropoiesis |
-
1997
- 1997-06-21 EP EP97110168A patent/EP0885613A1/de not_active Withdrawn
-
1998
- 1998-06-03 EP EP98930785A patent/EP0996462B1/de not_active Expired - Lifetime
- 1998-06-03 CA CA002294448A patent/CA2294448C/en not_active Expired - Lifetime
- 1998-06-03 AT AT98930785T patent/ATE272405T1/de active
- 1998-06-03 DK DK98930785T patent/DK0996462T3/da active
- 1998-06-03 CN CNB988064324A patent/CN1185010C/zh not_active Expired - Lifetime
- 1998-06-03 TR TR1999/03192T patent/TR199903192T2/tr unknown
- 1998-06-03 DE DE59811768T patent/DE59811768D1/de not_active Expired - Lifetime
- 1998-06-03 ES ES98930785T patent/ES2226151T3/es not_active Expired - Lifetime
- 1998-06-03 WO PCT/EP1998/003299 patent/WO1998058660A1/de active IP Right Grant
- 1998-06-03 PT PT98930785T patent/PT996462E/pt unknown
- 1998-06-03 US US09/446,378 patent/US6440932B1/en not_active Expired - Lifetime
- 1998-06-03 AU AU81098/98A patent/AU743475B2/en not_active Expired
- 1998-06-03 KR KR10-1999-7012111A patent/KR100519904B1/ko not_active IP Right Cessation
- 1998-06-03 JP JP50365599A patent/JP2002504913A/ja not_active Withdrawn
- 1998-06-03 BR BR9810267-2A patent/BR9810267A/pt not_active Application Discontinuation
-
2002
- 2002-05-08 US US10/140,682 patent/US20020160956A1/en not_active Abandoned
-
2005
- 2005-03-28 US US11/091,876 patent/US20050197281A1/en not_active Abandoned
-
2007
- 2007-04-23 JP JP2007113275A patent/JP2007246530A/ja not_active Withdrawn
-
2011
- 2011-07-08 JP JP2011151443A patent/JP5785008B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0885613A1 (de) | 1998-12-23 |
EP0996462B1 (de) | 2004-08-04 |
CN1261282A (zh) | 2000-07-26 |
KR20010014075A (ko) | 2001-02-26 |
JP2007246530A (ja) | 2007-09-27 |
JP2002504913A (ja) | 2002-02-12 |
ATE272405T1 (de) | 2004-08-15 |
US20050197281A1 (en) | 2005-09-08 |
KR100519904B1 (ko) | 2005-10-10 |
US20020160956A1 (en) | 2002-10-31 |
AU743475B2 (en) | 2002-01-24 |
CA2294448C (en) | 2007-12-11 |
DE59811768D1 (de) | 2004-09-09 |
JP5785008B2 (ja) | 2015-09-24 |
CN1185010C (zh) | 2005-01-19 |
EP0996462A1 (de) | 2000-05-03 |
AU8109898A (en) | 1999-01-04 |
DK0996462T3 (da) | 2004-11-29 |
JP2011246474A (ja) | 2011-12-08 |
ES2226151T3 (es) | 2005-03-16 |
WO1998058660A1 (de) | 1998-12-30 |
US6440932B1 (en) | 2002-08-27 |
PT996462E (pt) | 2004-12-31 |
BR9810267A (pt) | 2000-09-12 |
CA2294448A1 (en) | 1998-12-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TR199903192T2 (tr) | Eritropoetin, degistirilmis hemoglobin içeren farmasotik kombine müstahzarlar. | |
NZ236823A (en) | Topical pharmaceutical and cosmetic compositions containing a salt of cholanic acid, a lipid and optionally a pharmaceutically or cosmetically active substance | |
AU610636B2 (en) | Stabilised human protein preparations | |
ES2139678T5 (es) | Uso de eritropoyetina para la preparacion de una composicion farmaceutica para administracion pulmonar o inhalacion. | |
ES2130428T3 (es) | Cristales de insulina asp-b28. | |
EE9900075A (et) | 7a-( -aminoalküül)östratrieenid, nende valmistamise meetod, 7a-( -aminoalküül)östratrieene sisaldavad farmatseutilised preparaadid ja nende kasutamine ravimite valmistamiseks | |
DK0582239T3 (da) | Farmaceutisk og/eller kosmetisk formulering | |
ATE223204T1 (de) | Liposomenzusammensetzung | |
DE68902300D1 (de) | Pharmazeutische loesung enthaltend salbutamol und cromoglycinsaeure. | |
PT88539A (pt) | Stabilisierung von therapeutisch wirksamen proteinen in pharmazeutischen zubereitungen | |
EP0190860A3 (en) | 6-chloro-3-methyl-1h-2,3,4,5-tetrahydro-3-benzazepine-n-oxide and medical compositions using it | |
IL85651A0 (en) | Optically active oxo-isoindolinyl derivatives,their preparation and pharmaceutical compositions containing them | |
EP0418065A3 (en) | Dihydrocaffeic acid derivatives, use thereof for medical treatments and pharmaceutical preparations containing same | |
ATE45956T1 (de) | 11 beta-phenyl-gonane, deren herstellung und diese enthaltende pharmazeutische praeparate. | |
ATE78684T1 (de) | Pharmazeutische loesung enthaltend salbutamol und cromoglycinsaeure. | |
TR199902305T2 (tr) | Eritropoitein ve demir preperasyonlari içeren farmasötik birlesimli preperasyonlar. |