TR199902812T2 - Use of anti-inflammatory steroids for the treatment of chronic inflammatory bowel diseases. - Google Patents
Use of anti-inflammatory steroids for the treatment of chronic inflammatory bowel diseases.Info
- Publication number
- TR199902812T2 TR199902812T2 TR1999/02812T TR9902812T TR199902812T2 TR 199902812 T2 TR199902812 T2 TR 199902812T2 TR 1999/02812 T TR1999/02812 T TR 1999/02812T TR 9902812 T TR9902812 T TR 9902812T TR 199902812 T2 TR199902812 T2 TR 199902812T2
- Authority
- TR
- Turkey
- Prior art keywords
- bowel diseases
- treatment
- group
- inflammatory bowel
- steroids
- Prior art date
Links
- 208000022559 Inflammatory bowel disease Diseases 0.000 title abstract 2
- 230000001684 chronic effect Effects 0.000 title abstract 2
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
- 150000003431 steroids Chemical class 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Bulus, kronik enflamatuar bagirsak hastaliklari için bir ilacin imalatinda genel formül (I)'e sahip enflamatuar bilesiklerin kullanilmasina iliskindir; bu formülde X, H ve halojenden olusan grubun bir elemanidir; Y, H2, H(OH), H(O(C1-6)Asil) ve O'dan olusan grubun bir elemanidir; R1, H, CH3 ve halojenden olusan grubun bir elemanidir; R2, (C1-4)Alkil'dir; R3, H, O((C1-6)Asil), O((C1-6)Alkil) ve CH3'ten olusan grubun bir elemanidir; R4, H ve (C1-4)Alkil'den olusan grubun bir elemanidir ve C1-C2 ve C6-C7 doymus veya doymamis baglardir.The invention relates to the use of inflammatory compounds of general formula (I) in the manufacture of a medicament for chronic inflammatory bowel diseases; wherein X is an element of the group consisting of H and halogen; Y is a member of the group consisting of H2, H (OH), H (O (C1-6) Acyl) and O; R1 is a member of the group consisting of H, CH3 and halogen; R2 is (C1-4) Alkyl; R3 is a member of the group consisting of H, O ((C1-6) Acyl), O ((C1-6) Alkyl) and CH3; R4 is a member of the group consisting of H and (C1-4) Alkyl, and C1-C2 and C6-C7 are saturated or unsaturated bonds.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97201690 | 1997-06-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR199902812T2 true TR199902812T2 (en) | 2000-06-21 |
Family
ID=8228405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR1999/02812T TR199902812T2 (en) | 1997-06-04 | 1998-06-02 | Use of anti-inflammatory steroids for the treatment of chronic inflammatory bowel diseases. |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0984782A2 (en) |
| JP (1) | JP2002502409A (en) |
| KR (1) | KR20010013335A (en) |
| CN (1) | CN1336824A (en) |
| AU (1) | AU740005B2 (en) |
| BR (1) | BR9809551A (en) |
| CA (1) | CA2290775A1 (en) |
| HU (1) | HUP0003354A3 (en) |
| NO (1) | NO995936L (en) |
| PL (1) | PL337458A1 (en) |
| TR (1) | TR199902812T2 (en) |
| WO (1) | WO1998055126A2 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UY28126A1 (en) * | 2002-12-24 | 2004-06-30 | Alcon Inc | USE OF SELECTIVE GLUCOCORTICOIDS FOR THE EYE SURFACE IN THE TREATMENT OF EYE DROUGHT |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3947478A (en) * | 1972-01-12 | 1976-03-30 | Akzona Incorporated | Alkylated 3,20-diketo-Δ4 -steroids of the pregnane series |
| GB1416427A (en) * | 1972-01-12 | 1975-12-03 | Akzo Nv | Alkylated pregnanes and process for obtaining same |
| DE3064460D1 (en) * | 1979-01-24 | 1983-09-08 | Akzo Nv | Novel alkylated pregnanes, processes for their preparation and pharmaceutical compositions containing same |
| FR2747680B1 (en) * | 1996-04-18 | 1998-07-03 | Roussel Uclaf | NOVEL STEROIDS, THEIR APPLICATION AS MEDICAMENTS, THEIR PREPARATION PROCESS, THE INTERMEDIATES THEREOF AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
-
1998
- 1998-06-02 EP EP98937458A patent/EP0984782A2/en not_active Withdrawn
- 1998-06-02 CA CA002290775A patent/CA2290775A1/en not_active Abandoned
- 1998-06-02 JP JP50158399A patent/JP2002502409A/en active Pending
- 1998-06-02 HU HU0003354A patent/HUP0003354A3/en unknown
- 1998-06-02 KR KR19997011331A patent/KR20010013335A/en not_active Application Discontinuation
- 1998-06-02 WO PCT/EP1998/003473 patent/WO1998055126A2/en not_active Application Discontinuation
- 1998-06-02 TR TR1999/02812T patent/TR199902812T2/en unknown
- 1998-06-02 PL PL98337458A patent/PL337458A1/en unknown
- 1998-06-02 AU AU86252/98A patent/AU740005B2/en not_active Ceased
- 1998-06-02 BR BR9809551-0A patent/BR9809551A/en not_active IP Right Cessation
- 1998-06-02 CN CN98805806A patent/CN1336824A/en active Pending
-
1999
- 1999-12-03 NO NO995936A patent/NO995936L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| BR9809551A (en) | 2000-06-20 |
| PL337458A1 (en) | 2000-08-14 |
| AU8625298A (en) | 1998-12-21 |
| CN1336824A (en) | 2002-02-20 |
| HUP0003354A2 (en) | 2001-03-28 |
| EP0984782A2 (en) | 2000-03-15 |
| WO1998055126A2 (en) | 1998-12-10 |
| CA2290775A1 (en) | 1998-12-10 |
| NO995936D0 (en) | 1999-12-03 |
| WO1998055126A3 (en) | 1999-03-11 |
| NO995936L (en) | 1999-12-03 |
| KR20010013335A (en) | 2001-02-26 |
| AU740005B2 (en) | 2001-10-25 |
| JP2002502409A (en) | 2002-01-22 |
| HUP0003354A3 (en) | 2001-09-28 |
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