TR199900056T2 - Leptin direncinin yeni tedavisi. - Google Patents

Leptin direncinin yeni tedavisi.

Info

Publication number
TR199900056T2
TR199900056T2 TR1999/00056T TR9900056T TR199900056T2 TR 199900056 T2 TR199900056 T2 TR 199900056T2 TR 1999/00056 T TR1999/00056 T TR 1999/00056T TR 9900056 T TR9900056 T TR 9900056T TR 199900056 T2 TR199900056 T2 TR 199900056T2
Authority
TR
Turkey
Prior art keywords
leptin resistance
new treatment
leptin
treatment
resistance
Prior art date
Application number
TR1999/00056T
Other languages
English (en)
Turkish (tr)
Inventor
Henry Poste George
Alistair Smith Stephen
Original Assignee
Smithkline Beecham P.L.C.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9614740.0A external-priority patent/GB9614740D0/en
Priority claimed from GBGB9614751.7A external-priority patent/GB9614751D0/en
Priority claimed from GBGB9616409.0A external-priority patent/GB9616409D0/en
Priority claimed from GBGB9616407.4A external-priority patent/GB9616407D0/en
Priority claimed from GBGB9616412.4A external-priority patent/GB9616412D0/en
Application filed by Smithkline Beecham P.L.C. filed Critical Smithkline Beecham P.L.C.
Publication of TR199900056T2 publication Critical patent/TR199900056T2/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
TR1999/00056T 1996-07-12 1997-07-14 Leptin direncinin yeni tedavisi. TR199900056T2 (xx)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB9614740.0A GB9614740D0 (en) 1996-07-12 1996-07-12 Novel treatment
GBGB9614751.7A GB9614751D0 (en) 1996-07-12 1996-07-12 Novel treatment
GBGB9616409.0A GB9616409D0 (en) 1996-08-05 1996-08-05 Novel treatment
GBGB9616407.4A GB9616407D0 (en) 1996-08-05 1996-08-05 Novel treatment
GBGB9616412.4A GB9616412D0 (en) 1996-08-05 1996-08-05 Novel treatment

Publications (1)

Publication Number Publication Date
TR199900056T2 true TR199900056T2 (xx) 1999-04-21

Family

ID=27517363

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1999/00056T TR199900056T2 (xx) 1996-07-12 1997-07-14 Leptin direncinin yeni tedavisi.

Country Status (12)

Country Link
EP (1) EP0921798A1 (xx)
JP (1) JP2000514807A (xx)
KR (1) KR20000023719A (xx)
CN (1) CN1230114A (xx)
AU (1) AU3552697A (xx)
BR (1) BR9710272A (xx)
CA (1) CA2260044A1 (xx)
NO (1) NO990097L (xx)
PL (1) PL331148A1 (xx)
TR (1) TR199900056T2 (xx)
TW (1) TW442288B (xx)
WO (1) WO1998002159A1 (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9711683D0 (en) * 1997-06-05 1997-08-06 Smithkline Beecham Plc Composition
WO1999044598A2 (en) * 1998-03-03 1999-09-10 Board Of Regents, The University Of Texas System Methods for inhibiting βcell apoptosis
US7348426B1 (en) * 1999-04-28 2008-03-25 Dr. Reddy's Laboraties Limited Substituted bicyclic heterocycles, process for their preparation and their use as antiobesity and hypocholesterolemic agents
CA2440680C (en) 2001-03-12 2010-06-01 Roberto Pellicciari Steroids as agonists for fxr
JP4590159B2 (ja) * 2001-04-04 2010-12-01 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド グルコース再吸収阻害剤およびｐｐａｒモジュレーターを含んで成る併用療法
US6987123B2 (en) 2001-07-26 2006-01-17 Cadila Healthcare Limited Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine
US7618940B2 (en) * 2002-12-06 2009-11-17 Fibrogen, Inc. Fat regulation
JP5094384B2 (ja) 2004-03-12 2012-12-12 インターセプト ファーマシューティカルズ， インコーポレイテッド Ｆｘｒリガンドを使用する線維症の処置
US10987362B2 (en) 2004-03-12 2021-04-27 Intercept Pharmaceuticals, Inc. Treatment of fibrosis using FXR ligands
ITMI20050912A1 (it) 2005-05-19 2006-11-20 Erregierre Spa Processo di preparazione di acidi 3-a-ya(b)-diidrossi-6-a(b)-alchil-5b-colanici
AU2008209566C1 (en) 2007-01-19 2013-02-14 Intercept Pharmaceuticals, Inc. 23-substituted bile acids as TGR5 modulators and methods of use thereof
CA2732323C (en) 2008-07-30 2017-06-27 Intercept Pharmaceuticals, Inc. Tgr5 modulators and methods of use thereof
JP5535233B2 (ja) 2008-11-19 2014-07-02 インターセプト ファーマシューティカルズ， インコーポレイテッド Ｔｇｒ５モジュレーターおよびその使用方法
US9982008B2 (en) 2012-06-19 2018-05-29 Intercept Pharmaceuticals, Inc. Preparation and uses of obeticholic acid
CA3047776C (en) 2012-06-19 2022-10-18 Intercept Pharmaceuticals, Inc. Preparation, uses and solid forms of obeticholic acid

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6051189A (ja) * 1983-08-30 1985-03-22 Sankyo Co Ltd チアゾリジン誘導体およびその製造法
DK0601001T3 (da) * 1991-08-26 1997-10-20 Upjohn Co Flydende næringsmiddelprodukt indeholdende 3-guanidinopropionsyre.
GB9218830D0 (en) * 1992-09-05 1992-10-21 Smithkline Beecham Plc Novel compounds

Also Published As

Publication number Publication date
NO990097D0 (no) 1999-01-11
BR9710272A (pt) 1999-08-10
PL331148A1 (en) 1999-06-21
JP2000514807A (ja) 2000-11-07
CA2260044A1 (en) 1998-01-22
AU3552697A (en) 1998-02-09
CN1230114A (zh) 1999-09-29
TW442288B (en) 2001-06-23
NO990097L (no) 1999-01-11
WO1998002159A1 (en) 1998-01-22
KR20000023719A (ko) 2000-04-25
EP0921798A1 (en) 1999-06-16

Similar Documents

Publication Publication Date Title
TR199900056T2 (xx) Leptin direncinin yeni tedavisi.
ATE234323T1 (de) N6-heterocyclisch substituierte adenosin-derivate
DE69730043D1 (de) Implantierbare eletrodenleitung
BR9605486A (pt) Pneumático tendo uma armadura de carcaça radial
DE69732105D1 (de) Programmerweiterbare, implantierbare, medizinische vorrichtung
IS4963A (is) Setnar 6,5-heteró-bísýklískar afleiður
LU91122I2 (fr) Efalizumab et ses dérivés pharmaceutiquement acceptables (raptiva).
ZA961291B (en) Naphthyl compounds, intermediates, compositions, and methods.
GR3034564T3 (en) Lactone derivatives of 17.beta.-carboxy, carbothio and amide androstane derivatives
ZA972500B (en) Fluorescent-tagged polymers for boiler internal treatment.
RS49723B (sr) Farmaceutska kompozicija koja sadrži entakapon ili nitekapon kao i umreženi derivat celuloze
TR28098A (tr) 1,2,4-okzadiazol türevleri.
EP0641209A4 (en) NEW 17-ESTER, AMID AND KETONE DERIVATIVES OF 3-OXO-4-AZASTEROIDS AS 5-ALPHA REDUCTINE INHIBITORS.
ZA973707B (en) Method for treating inflammation.
EP1135144A4 (en) COMPOSITIONS AND METHODS OF REGULATING BACTERIAL PATHOGENESIS
EP0679603A3 (en) Method for adjusting an elevator door.
AU6198299A (en) Device and method for sterilising screwcaps
AU2001289123A1 (en) Compounds and methods for diagnosing and treating amyloid-related conditions
ZA966749B (en) Endoparasiticidal compositions based on didepsipeptides, new didepsipeptides and processes for their preparation.
TR199600373A2 (tr) Ensektisid olarak benzofenon hidrazon türevleri.
EP0779960A4 (en) FUEL CONTROL DEVICE, PARTS OF SUCH A DEVICE AND METHOD FOR THE PRODUCTION THEREOF
TW336890B (en) Method of making more than one punchout from a single dried blood spot
EP1083914A4 (en) TREATING ARTHRITIS AND OTHER SIMILAR DISORDERS
DE59508403D1 (de) 14alpha,17alpha-c2-überbrückte 19-nor-progesteronderivate
BR9510036A (pt) Derivados de 1,3,4-oxadiazina