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Priority claimed from PCT/IB2003/005607external-prioritypatent/WO2004052894A1/en
Application filed by Pharmacia & Upjohn Co LlcfiledCriticalPharmacia & Upjohn Co Llc
Publication of TNSN05156A1publicationCriticalpatent/TNSN05156A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
La présente invention propose des sels consistant en fumarates de N-(1-azabicyclo (2.2.2) oct-3-yl) furo (2,3-c)pyridine-5-carboxamide, des compositions les contenant, leurs mélanges racémiques ou leurs énantiomères purs, et leur préparation. Les sels consistant en fumarates sont utiles pour traiter des maladies ou affections dans lesquelles on sait qu' alpha 7nAChR est impliqué. Formule (I).The present invention provides salts of N- (1-azabicyclo (2.2.2) oct-3-yl) furo (2,3-c) pyridine-5-carboxamide fumarates, compositions containing them, racemic mixtures thereof or their pure enantiomers, and their preparation. Fumarate salts are useful for treating diseases or conditions in which alpha 7nAChR is known to be involved. Formula (I).
TNP2005000156A2003-12-012005-06-06
1-AZABICYCLO [2,2,2] OCTYL-SUBSTITUTED FURO [2,3-C] PYRIDINYLCARBOXAMIDE CRYSTALLINE FUMARATED SALTS, COMPOSITIONS CONTAINING SAME, AND THEIR PREPARATION
TNSN05156A1
(en)
CRYSTALLINE FURAR SALTS OF FURO [2,3-C] PYRIDINYLCARBOXAMIDE WITH SUBSTITUTE 1- AZABICYCLO [2.2.2] OCTYL, COMPOSITIONS CONTAINING THEM, AND THEIR PREPARATION
5,7-diaminopyrazolo[4,3-d]pyrimidines with pde-5 inhibitory activity, compositions containing such derivatives and the use of such derivatives in the treatment of hypertension and other disorders
Novel derivatives of n-(arylsulfonyl)beta-aminoacids comprising a substituted aminomethyl group, the preparation method thereof and pharmaceutical compositions containing same