TN2014000401A1 - Microrna compounds and methods for modulating mir-21 activity - Google Patents

Microrna compounds and methods for modulating mir-21 activity

Info

Publication number
TN2014000401A1
TN2014000401A1 TNP2014000401A TN2014000401A TN2014000401A1 TN 2014000401 A1 TN2014000401 A1 TN 2014000401A1 TN P2014000401 A TNP2014000401 A TN P2014000401A TN 2014000401 A TN2014000401 A TN 2014000401A TN 2014000401 A1 TN2014000401 A1 TN 2014000401A1
Authority
TN
Tunisia
Prior art keywords
activity
mir
methods
compositions
modulating mir
Prior art date
Application number
TNP2014000401A
Other languages
French (fr)
Inventor
Balkrishen Bhat
Eric Marcusson
Original Assignee
Regulus Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2013/037913 external-priority patent/WO2013163258A1/en
Application filed by Regulus Therapeutics Inc filed Critical Regulus Therapeutics Inc
Publication of TN2014000401A1 publication Critical patent/TN2014000401A1/en

Links

Abstract

Described herein are compositions and methods for the inhibition of miR-21 activity. The compositions have certain nucleoside modification patterns that yield potent inhibitors of miR-21 activity. The compositions may be used to inhibit miR-21, and also to treat diseases associated with abnormal expression of miR-21, such as fibrosis and cancer.
TNP2014000401A 2013-03-13 2014-09-24 Microrna compounds and methods for modulating mir-21 activity TN2014000401A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361779913P 2013-03-13 2013-03-13
PCT/US2013/037913 WO2013163258A1 (en) 2012-04-25 2013-04-24 Microrna compounds and methods for modulating mir-21 activity

Publications (1)

Publication Number Publication Date
TN2014000401A1 true TN2014000401A1 (en) 2015-12-21

Family

ID=55447253

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2014000401A TN2014000401A1 (en) 2013-03-13 2014-09-24 Microrna compounds and methods for modulating mir-21 activity

Country Status (1)

Country Link
TN (1) TN2014000401A1 (en)

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