TN2011000009A1 - Pyridazne derivatives as smo inhibitors - Google Patents

Pyridazne derivatives as smo inhibitors

Info

Publication number
TN2011000009A1
TN2011000009A1 TN2011000009A TN2011000009A TN2011000009A1 TN 2011000009 A1 TN2011000009 A1 TN 2011000009A1 TN 2011000009 A TN2011000009 A TN 2011000009A TN 2011000009 A TN2011000009 A TN 2011000009A TN 2011000009 A1 TN2011000009 A1 TN 2011000009A1
Authority
TN
Tunisia
Prior art keywords
methods
agents
pyridazne
derivatives
tumor
Prior art date
Application number
TN2011000009A
Other languages
French (fr)
Inventor
Naeem Yusuff
Zhuoliang Chen
Bharat Lagu
Feng He
Stfan Peukert
Moslin Karen Miller
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2009/059138 external-priority patent/WO2010007120A1/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of TN2011000009A1 publication Critical patent/TN2011000009A1/en

Links

Abstract

The present invention relates generally to novel compounds relating to the diagnosis and treatment of pathologies relating to the Hedgehog pathway, including but not limited to tumor formation, cancer, neoplasia, and non-malignant hyperproliferative disorders. The present invention includes novel compounds, novel compositions, methods of their use and methods of their manufacture, where such compounds are generally pharmacologically useful as agents in therapies whose mechanism of action involve methods of inhibiting tumorigenesis, tumor growth and tumor survival using agents that inhibit the Hedgehog and Smo signaling pathway.
TN2011000009A 2009-07-16 2011-01-07 Pyridazne derivatives as smo inhibitors TN2011000009A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2009/059138 WO2010007120A1 (en) 2008-07-18 2009-07-16 Pyridazine derivatives as smo inhibitors

Publications (1)

Publication Number Publication Date
TN2011000009A1 true TN2011000009A1 (en) 2012-09-05

Family

ID=55024324

Family Applications (1)

Application Number Title Priority Date Filing Date
TN2011000009A TN2011000009A1 (en) 2009-07-16 2011-01-07 Pyridazne derivatives as smo inhibitors

Country Status (1)

Country Link
TN (1) TN2011000009A1 (en)

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