TH76320A - Quinazolinone derivative for PARP inhibitors - Google Patents
Quinazolinone derivative for PARP inhibitorsInfo
- Publication number
- TH76320A TH76320A TH501002994A TH0501002994A TH76320A TH 76320 A TH76320 A TH 76320A TH 501002994 A TH501002994 A TH 501002994A TH 0501002994 A TH0501002994 A TH 0501002994A TH 76320 A TH76320 A TH 76320A
- Authority
- TH
- Thailand
- Prior art keywords
- formula
- compound
- parp inhibitors
- chemical formula
- substance
- Prior art date
Links
- 229920000776 Poly(Adenosine diphosphate-ribose) polymerase Polymers 0.000 title claims abstract 5
- 239000003112 inhibitor Substances 0.000 title claims abstract 5
- 230000002401 inhibitory effect Effects 0.000 title claims abstract 5
- AVRPFRMDMNDIDH-UHFFFAOYSA-N 1H-quinazolin-2-one Chemical class C1=CC=CC2=NC(O)=NC=C21 AVRPFRMDMNDIDH-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims abstract 9
- 239000000126 substance Substances 0.000 claims abstract 9
- 101700007241 APOC4 Proteins 0.000 claims abstract 4
- 101710038729 F2R Proteins 0.000 claims abstract 4
- 101700036247 PARP1 Proteins 0.000 claims abstract 4
- 102100014579 PARP1 Human genes 0.000 claims abstract 4
- 101700053624 PARP2 Proteins 0.000 claims abstract 4
- 101700027237 PROA Proteins 0.000 claims abstract 4
- 101700004528 arp Proteins 0.000 claims abstract 4
- 239000000470 constituent Substances 0.000 claims abstract 2
- 239000003814 drug Substances 0.000 claims abstract 2
- 229940079593 drugs Drugs 0.000 claims abstract 2
- 239000000203 mixture Substances 0.000 claims abstract 2
Abstract
DC60 (26/09/48) การประดิษฐ์นี้ให้สารประกอบตามสูตร (I), การใช้สารนี้เป็นสารยับยั้ง PARP และสารผสม ทางเภสัชกรรมซึ่งประกอบรวมด้วยสารประกอบตามสูตร (I) ดังกล่าว (สูตรเคมี) (I) ซึ่ง R1, R2, R3, L, X, Y และ Z มีความหมายตามที่กำหนด การประดิษฐ์นี้ให้สารประกอบตามสูตร (I), การใช้สารนี้เป็นสารยับยั้ง PARP และ องค์ประกอบทางเภสัชกรรมซึ่งประกอบรวมด้วยสารประกอบตามสูตร (I) ดังกล่าว (สูตรเคมี) (I) ซึ่ง R1, R2, R3, L, X, Y และ Z มีความหมายตามที่กำหนด สิทธิบัตรยา DC60 (26/09/48) This invention provides a compound according to formula (I), the use of this substance as a PARP inhibitor and a pharmaceutical mixtures comprising such (I) compounds (chemical formula) (I). Where R1, R2, R3, L, X, Y and Z have the given meanings. This invention provides a compound according to the formula (I), the use of this substance as a PARP inhibitor and a pharmaceutical constituent of the above (I) compound (chemical formula) (I), where R1, R2, R3, L, X, Y, and Z are synonymous with drug patents.
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH76320A true TH76320A (en) | 2006-03-09 |
Family
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