SU950735A1 - Process for producing hyaluronic acid - Google Patents
Process for producing hyaluronic acid Download PDFInfo
- Publication number
- SU950735A1 SU950735A1 SU802998957A SU2998957A SU950735A1 SU 950735 A1 SU950735 A1 SU 950735A1 SU 802998957 A SU802998957 A SU 802998957A SU 2998957 A SU2998957 A SU 2998957A SU 950735 A1 SU950735 A1 SU 950735A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- hyaluronic acid
- umbilical
- umbilical cord
- acetone
- washed
- Prior art date
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- Polysaccharides And Polysaccharide Derivatives (AREA)
Description
(54) СПОСОБ ПОЛУЧЕНИЯ ГИАЛУТОНОВОЙ КИСЛОТЫ(54) METHOD FOR OBTAINING HYALUTONIC ACID
1one
Изобретение относитс к бнохнмин, а именно к способам получени полисахаридов.The invention relates to bnohmin, namely to methods for producing polysaccharides.
Известен способ получени гиалуроновой кислоты, заключающийс в том, что пуповину человека, отмытую от крови, обезвоживают Н обезжиривают ацетоном, затем измельчают на м сорубке.A known method for producing hyaluronic acid is that the human umbilical cord, washed with blood, is dehydrated H is degreased with acetone, then crushed in a miter.
Полученный порошок заливают водой, размешивают и центрифугируют. К надосадочной жидкости приливают ацетон, гиалурннова кислота вьшадает в осадок, который собирают и сушат. Данна обработка Дает выход 6%-ной гналуроновой кислоты с относительной в зкостью 1%-ного раствора 3,0 1.The resulting powder is poured with water, stirred and centrifuged. Acetone is added to the supernatant, hyalurn acid is precipitated, which is collected and dried. This treatment gives a yield of 6% gnaluronic acid with a relative viscosity of 1% solution 3.0 1.
Недостатком указанного способа вл етс малый выход вещества и его относнтельно низка в зкость.The disadvantage of this method is the low yield of the substance and its relatively low viscosity.
Цель нзобретени - повышение выхода целевого продукта и в зкости получаемых из него растворов.The purpose of the invention is to increase the yield of the target product and the viscosity of the solutions obtained from it.
Поставленна цель достигаетс тем, что согласно способу получени гиалуроновой кислрты , заключающемус в нзмельченин пуповиныThe goal is achieved by the fact that, according to the method of obtaining hyaluronic acid, which consists in cutting the umbilical cord
человека, ее обезвоживании, обезжиривании, последующей обработке дастнллированной водой , центрифугировании и выделении целевого продукта, после обработки сырь .водой полученную- смесь выдерживают на холоде, гомогенизируют и гомогенат нагревают на кип щей вод ной бане в течение 5-15 мин.man, its dehydration, degreasing, subsequent processing with distilled water, centrifugation and isolation of the target product, after processing the raw material with water, the mixture is kept cold, homogenized and the homogenate is heated in a boiling water bath for 5-15 minutes.
Способ осуществл етс следующим образом.The method is carried out as follows.
Claims (1)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SU802998957A SU950735A1 (en) | 1980-10-28 | 1980-10-28 | Process for producing hyaluronic acid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SU802998957A SU950735A1 (en) | 1980-10-28 | 1980-10-28 | Process for producing hyaluronic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
SU950735A1 true SU950735A1 (en) | 1982-08-15 |
Family
ID=20924093
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SU802998957A SU950735A1 (en) | 1980-10-28 | 1980-10-28 | Process for producing hyaluronic acid |
Country Status (1)
Country | Link |
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SU (1) | SU950735A1 (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4517295A (en) * | 1983-02-18 | 1985-05-14 | Diagnostic, Inc. | Hyaluronic acid from bacterial culture |
FR2582002A1 (en) * | 1985-03-12 | 1986-11-21 | Biomatrix Inc | CHEMICALLY MODIFIED HYALURONIC ACID PREPARATION AND PROCESS FOR OBTAINING IT FROM ANIMAL TISSUE |
RU2805084C1 (en) * | 2023-03-30 | 2023-10-11 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный университет инженерных технологий" (ФГБОУ ВО "ВГУИТ") | Method for obtaining hyaluronic acid |
-
1980
- 1980-10-28 SU SU802998957A patent/SU950735A1/en active
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4517295A (en) * | 1983-02-18 | 1985-05-14 | Diagnostic, Inc. | Hyaluronic acid from bacterial culture |
FR2582002A1 (en) * | 1985-03-12 | 1986-11-21 | Biomatrix Inc | CHEMICALLY MODIFIED HYALURONIC ACID PREPARATION AND PROCESS FOR OBTAINING IT FROM ANIMAL TISSUE |
RU2805084C1 (en) * | 2023-03-30 | 2023-10-11 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный университет инженерных технологий" (ФГБОУ ВО "ВГУИТ") | Method for obtaining hyaluronic acid |
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