SU843757A3 - Способ получени -ди-бензоилокси- -эТиНил- -МЕТил- -эСТРАТРи-EH- -ТРиОлА - Google Patents

Способ получени -ди-бензоилокси- -эТиНил- -МЕТил- -эСТРАТРи-EH- -ТРиОлА Download PDF

Info

Publication number
SU843757A3
SU843757A3 SU792745050A SU2745050A SU843757A3 SU 843757 A3 SU843757 A3 SU 843757A3 SU 792745050 A SU792745050 A SU 792745050A SU 2745050 A SU2745050 A SU 2745050A SU 843757 A3 SU843757 A3 SU 843757A3
Authority
SU
USSR - Soviet Union
Prior art keywords
alpha
triol
ethynyl
methyl
estatriene
Prior art date
Application number
SU792745050A
Other languages
English (en)
Inventor
Прецевовски Клаус
Штайнбек Херманн
Вихерт Рудольф
Original Assignee
Шеринг Аг (Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Шеринг Аг (Фирма) filed Critical Шеринг Аг (Фирма)
Application granted granted Critical
Publication of SU843757A3 publication Critical patent/SU843757A3/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0081—Substituted in position 17 alfa and 17 beta
    • C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0096—Alkynyl derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Description

бенэоилхлорида с последующим выделением целевого продукта.
Источники информации, прин тые во внимание при экспертизе
1,Патент ФРГ 1593509,
кл. С 07 J 1/00, опублик. 1976.
2.Вейганд-Хильгетаг. Методы эксперимента в органической химии. М., Хими , 1968, с.349.

Claims (1)

  1. Формула изобретения
    Способ получения,1,3-ди-бензоилокси-1 ^-этинил-7о6-метил-1,3,5 (10)-эстратриен-1,3,17[5-триола, о т л и чающийся тем, что 17сё-этинил~ -7э6-метил~1,3,5 (10) -эстратриен-1,3, 17р)-триол этерифицируют с помощью бенэоилхлорида с последующим выделением целевого продукта.
SU792745050A 1978-04-21 1979-04-06 Способ получени -ди-бензоилокси- -эТиНил- -МЕТил- -эСТРАТРи-EH- -ТРиОлА SU843757A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782818164 DE2818164A1 (de) 1978-04-21 1978-04-21 1,3-dibenzoesaeureester des 17alpha- ethinyl-7 alpha -methyl-1,3,5(10)-oestratrien- 1,3,17 beta -triols, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen

Publications (1)

Publication Number Publication Date
SU843757A3 true SU843757A3 (ru) 1981-06-30

Family

ID=6037985

Family Applications (1)

Application Number Title Priority Date Filing Date
SU792745050A SU843757A3 (ru) 1978-04-21 1979-04-06 Способ получени -ди-бензоилокси- -эТиНил- -МЕТил- -эСТРАТРи-EH- -ТРиОлА

Country Status (17)

Country Link
US (1) US4259325A (ru)
EP (1) EP0004898B1 (ru)
JP (1) JPS54141756A (ru)
AT (1) AT366065B (ru)
AU (1) AU521011B2 (ru)
CA (1) CA1123426A (ru)
CS (1) CS203036B2 (ru)
DD (1) DD143077A5 (ru)
DE (2) DE2818164A1 (ru)
DK (1) DK153279A (ru)
ES (1) ES479691A1 (ru)
GR (1) GR73572B (ru)
HU (1) HU179069B (ru)
IE (1) IE48133B1 (ru)
IL (1) IL57072A (ru)
SU (1) SU843757A3 (ru)
YU (1) YU78679A (ru)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3022337A1 (de) * 1980-06-11 1982-01-07 Schering Ag Berlin Und Bergkamen, 1000 Berlin Praeparate zur kontrazeption und zur behandlung gynaekologischer stoerungen
US4757062A (en) * 1985-11-01 1988-07-12 E. I. Du Pont De Nemours And Company Substituted benzoate ester prodrugs of estrogens
US5188835A (en) * 1986-06-16 1993-02-23 Kabi Pharmacia Ab Intravaginal devices
PT792152E (pt) 1994-11-22 2004-07-30 Balance Pharmaceuticals Inc Metodos de contracepcao
US7989436B2 (en) * 2003-07-23 2011-08-02 Duramed Pharmaceuticals, Inc. Estrogenic compounds and pharmaceutical formulations comprising the same
US6660726B2 (en) * 2000-03-10 2003-12-09 Endeavor Pharmaceuticals Estrogenic compounds, pharmaceutical compositions thereof, and methods of using same
US6855703B1 (en) 2000-03-10 2005-02-15 Endeavor Pharmaceuticals Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds
US7459445B2 (en) * 2000-03-10 2008-12-02 Duramed Pharmaceuticals, Inc. Estrogenic compounds and topical pharmaceutical formulations of the same
US6992075B2 (en) * 2003-04-04 2006-01-31 Barr Laboratories, Inc. C(14) estrogenic compounds
WO2004091535A2 (en) * 2003-04-11 2004-10-28 Barr Laboratories, Inc. Methods of administering estrogens and progestins
US20060183724A1 (en) * 2005-02-03 2006-08-17 Diliberti Charles E Compositions of unconjugated estrogens and methods for their use
JP5357108B2 (ja) * 2010-06-29 2013-12-04 大陽日酸株式会社 バーナの燃焼方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2861086A (en) * 1957-12-27 1958-11-18 Searle & Co 17-oxygenated estra-1, 3, 5(10)-triene-1, 3-diols, and the corresponding esters and ethers
US3024256A (en) * 1961-02-20 1962-03-06 Searle & Co 16-substituted 1, 3-diacyloxyestra-1, 3, 5(10)-trien-17-ones
DE1240859B (de) * 1963-11-09 1967-05-24 Schering Ag Verfahren zur Herstellung von Androstan-1alpha, 3alpha, 17beta-triol und seinen Estern
FR1580268A (ru) * 1968-06-10 1969-09-05
US3574197A (en) * 1968-07-09 1971-04-06 Schering Ag Process of producing 1-hydroxy-7alpha-methyl-estradiol derivatives
NL7409498A (nl) * 1973-07-13 1975-01-15 Schering Ag Werkwijze ter bereiding van een geneesmiddel met oestrogeenwerking.

Also Published As

Publication number Publication date
DE2818164A1 (de) 1979-10-31
DE2962423D1 (en) 1982-05-19
DD143077A5 (de) 1980-07-30
JPS54141756A (en) 1979-11-05
YU78679A (en) 1983-02-28
AU4627679A (en) 1979-10-25
IL57072A (en) 1982-07-30
AT366065B (de) 1982-03-10
CA1123426A (en) 1982-05-11
ES479691A1 (es) 1979-08-01
DK153279A (da) 1979-10-22
GR73572B (ru) 1984-03-19
AU521011B2 (en) 1982-03-11
IE790821L (en) 1979-10-21
ATA296079A (de) 1981-07-15
CS203036B2 (en) 1981-02-27
HU179069B (en) 1982-08-28
EP0004898A1 (de) 1979-10-31
IL57072A0 (en) 1979-07-25
US4259325A (en) 1981-03-31
EP0004898B1 (de) 1982-04-07
IE48133B1 (en) 1984-10-03

Similar Documents

Publication Publication Date Title
SU843757A3 (ru) Способ получени -ди-бензоилокси- -эТиНил- -МЕТил- -эСТРАТРи-EH- -ТРиОлА
DE3882242D1 (de) Fermentationsverfahren zur herstellung von 2-keto-l-gulonsaeuren.
CA1032545A (en) Process for the manufacture of substituted o-cyanobenzoic acid esters
CA1010597A (en) Process for producing polycarboxylates having improved biological degradability
SE7408642L (ru)
AU5852773A (en) Process for the manufacture of beta-(3-oxo-7a-acetylethio-17beta-hydroxy-4-androstene-17a-yl)-propionic acid-lactone
CA978999A (en) Process for the production of ortho-dihydrocarbylphosphinobenzoic acids
CA1007661A (en) Process for the production of 2,4-dihydroxy-benzophenone
CA975376A (en) Process for production of magnesium. aminodicarboxylic acid. halogen complexes
CA977976A (en) Method of repressing the precipitation of calcium fluozirconate
BE799477A (fr) Procede accelere d'alcoolyse ou de phenolyse du pentasulfure de phosphore,
CA1026761A (en) Process for the production of hydroxy substituted bis-(4-oxo-4h-benzopyran-2-derivatives)
SU434729A1 (ru) Способ получени винильных производных аценафтена и флуорена
CA1006815A (en) Process for the cultivation of fungi
CA906487A (en) Method for the production of substituted metanilic acids
CA992095A (en) Process for the isomerization of cis-isomeric hexadlenoic acids
AU446965B2 (en) Method of removing esterase from microbial rennin
AU3967972A (en) Process forthe cultivation of fungi
CA829882A (en) Method of producing magnesium by the electrolysis of magnesium chloride
DE3261924D1 (en) Process for the preparation of 3,3-dimethylglutaric acid or its esters
CA909014A (en) Method for the production of horticultural soils
AU447851B2 (en) Method of producing 4, 4 dimethyl dioxane 1, 3
CA909251A (en) Process for the manufacture of alkane phosphonic acid diesters
CA904880A (en) Process for producing triethylaluminum
CA903123A (en) Process for producing imidazoleglycerol by fermentation