SU843757A3 - Способ получени -ди-бензоилокси- -эТиНил- -МЕТил- -эСТРАТРи-EH- -ТРиОлА - Google Patents
Способ получени -ди-бензоилокси- -эТиНил- -МЕТил- -эСТРАТРи-EH- -ТРиОлА Download PDFInfo
- Publication number
- SU843757A3 SU843757A3 SU792745050A SU2745050A SU843757A3 SU 843757 A3 SU843757 A3 SU 843757A3 SU 792745050 A SU792745050 A SU 792745050A SU 2745050 A SU2745050 A SU 2745050A SU 843757 A3 SU843757 A3 SU 843757A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- alpha
- triol
- ethynyl
- methyl
- estatriene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
- C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0096—Alkynyl derivatives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Description
бенэоилхлорида с последующим выделением целевого продукта.
Источники информации, прин тые во внимание при экспертизе
1,Патент ФРГ 1593509,
кл. С 07 J 1/00, опублик. 1976.
2.Вейганд-Хильгетаг. Методы эксперимента в органической химии. М., Хими , 1968, с.349.
Claims (1)
- Формула изобретенияСпособ получения,1,3-ди-бензоилокси-1 ^-этинил-7о6-метил-1,3,5 (10)-эстратриен-1,3,17[5-триола, о т л и чающийся тем, что 17сё-этинил~ -7э6-метил~1,3,5 (10) -эстратриен-1,3, 17р)-триол этерифицируют с помощью бенэоилхлорида с последующим выделением целевого продукта.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19782818164 DE2818164A1 (de) | 1978-04-21 | 1978-04-21 | 1,3-dibenzoesaeureester des 17alpha- ethinyl-7 alpha -methyl-1,3,5(10)-oestratrien- 1,3,17 beta -triols, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen |
Publications (1)
Publication Number | Publication Date |
---|---|
SU843757A3 true SU843757A3 (ru) | 1981-06-30 |
Family
ID=6037985
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SU792745050A SU843757A3 (ru) | 1978-04-21 | 1979-04-06 | Способ получени -ди-бензоилокси- -эТиНил- -МЕТил- -эСТРАТРи-EH- -ТРиОлА |
Country Status (17)
Country | Link |
---|---|
US (1) | US4259325A (ru) |
EP (1) | EP0004898B1 (ru) |
JP (1) | JPS54141756A (ru) |
AT (1) | AT366065B (ru) |
AU (1) | AU521011B2 (ru) |
CA (1) | CA1123426A (ru) |
CS (1) | CS203036B2 (ru) |
DD (1) | DD143077A5 (ru) |
DE (2) | DE2818164A1 (ru) |
DK (1) | DK153279A (ru) |
ES (1) | ES479691A1 (ru) |
GR (1) | GR73572B (ru) |
HU (1) | HU179069B (ru) |
IE (1) | IE48133B1 (ru) |
IL (1) | IL57072A (ru) |
SU (1) | SU843757A3 (ru) |
YU (1) | YU78679A (ru) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3022337A1 (de) * | 1980-06-11 | 1982-01-07 | Schering Ag Berlin Und Bergkamen, 1000 Berlin | Praeparate zur kontrazeption und zur behandlung gynaekologischer stoerungen |
US4757062A (en) * | 1985-11-01 | 1988-07-12 | E. I. Du Pont De Nemours And Company | Substituted benzoate ester prodrugs of estrogens |
US5188835A (en) * | 1986-06-16 | 1993-02-23 | Kabi Pharmacia Ab | Intravaginal devices |
PT792152E (pt) | 1994-11-22 | 2004-07-30 | Balance Pharmaceuticals Inc | Metodos de contracepcao |
US7989436B2 (en) * | 2003-07-23 | 2011-08-02 | Duramed Pharmaceuticals, Inc. | Estrogenic compounds and pharmaceutical formulations comprising the same |
US6660726B2 (en) * | 2000-03-10 | 2003-12-09 | Endeavor Pharmaceuticals | Estrogenic compounds, pharmaceutical compositions thereof, and methods of using same |
US6855703B1 (en) | 2000-03-10 | 2005-02-15 | Endeavor Pharmaceuticals | Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds |
US7459445B2 (en) * | 2000-03-10 | 2008-12-02 | Duramed Pharmaceuticals, Inc. | Estrogenic compounds and topical pharmaceutical formulations of the same |
US6992075B2 (en) * | 2003-04-04 | 2006-01-31 | Barr Laboratories, Inc. | C(14) estrogenic compounds |
WO2004091535A2 (en) * | 2003-04-11 | 2004-10-28 | Barr Laboratories, Inc. | Methods of administering estrogens and progestins |
US20060183724A1 (en) * | 2005-02-03 | 2006-08-17 | Diliberti Charles E | Compositions of unconjugated estrogens and methods for their use |
JP5357108B2 (ja) * | 2010-06-29 | 2013-12-04 | 大陽日酸株式会社 | バーナの燃焼方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2861086A (en) * | 1957-12-27 | 1958-11-18 | Searle & Co | 17-oxygenated estra-1, 3, 5(10)-triene-1, 3-diols, and the corresponding esters and ethers |
US3024256A (en) * | 1961-02-20 | 1962-03-06 | Searle & Co | 16-substituted 1, 3-diacyloxyestra-1, 3, 5(10)-trien-17-ones |
DE1240859B (de) * | 1963-11-09 | 1967-05-24 | Schering Ag | Verfahren zur Herstellung von Androstan-1alpha, 3alpha, 17beta-triol und seinen Estern |
FR1580268A (ru) * | 1968-06-10 | 1969-09-05 | ||
US3574197A (en) * | 1968-07-09 | 1971-04-06 | Schering Ag | Process of producing 1-hydroxy-7alpha-methyl-estradiol derivatives |
NL7409498A (nl) * | 1973-07-13 | 1975-01-15 | Schering Ag | Werkwijze ter bereiding van een geneesmiddel met oestrogeenwerking. |
-
1978
- 1978-04-21 DE DE19782818164 patent/DE2818164A1/de not_active Withdrawn
-
1979
- 1979-03-31 DE DE7979101000T patent/DE2962423D1/de not_active Expired
- 1979-03-31 EP EP79101000A patent/EP0004898B1/de not_active Expired
- 1979-04-03 YU YU00786/79A patent/YU78679A/xx unknown
- 1979-04-06 SU SU792745050A patent/SU843757A3/ru active
- 1979-04-06 CS CS792363A patent/CS203036B2/cs unknown
- 1979-04-07 GR GR58834A patent/GR73572B/el unknown
- 1979-04-10 US US06/028,744 patent/US4259325A/en not_active Expired - Lifetime
- 1979-04-11 DK DK153279A patent/DK153279A/da not_active IP Right Cessation
- 1979-04-15 IL IL57072A patent/IL57072A/xx unknown
- 1979-04-18 ES ES479691A patent/ES479691A1/es not_active Expired
- 1979-04-18 DD DD79212298A patent/DD143077A5/de unknown
- 1979-04-19 AT AT0296079A patent/AT366065B/de not_active IP Right Cessation
- 1979-04-20 CA CA325,941A patent/CA1123426A/en not_active Expired
- 1979-04-20 JP JP4811179A patent/JPS54141756A/ja active Pending
- 1979-04-20 HU HU79SCHE676A patent/HU179069B/hu unknown
- 1979-04-23 AU AU46276/79A patent/AU521011B2/en not_active Ceased
- 1979-08-08 IE IE821/79A patent/IE48133B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
DE2818164A1 (de) | 1979-10-31 |
DE2962423D1 (en) | 1982-05-19 |
DD143077A5 (de) | 1980-07-30 |
JPS54141756A (en) | 1979-11-05 |
YU78679A (en) | 1983-02-28 |
AU4627679A (en) | 1979-10-25 |
IL57072A (en) | 1982-07-30 |
AT366065B (de) | 1982-03-10 |
CA1123426A (en) | 1982-05-11 |
ES479691A1 (es) | 1979-08-01 |
DK153279A (da) | 1979-10-22 |
GR73572B (ru) | 1984-03-19 |
AU521011B2 (en) | 1982-03-11 |
IE790821L (en) | 1979-10-21 |
ATA296079A (de) | 1981-07-15 |
CS203036B2 (en) | 1981-02-27 |
HU179069B (en) | 1982-08-28 |
EP0004898A1 (de) | 1979-10-31 |
IL57072A0 (en) | 1979-07-25 |
US4259325A (en) | 1981-03-31 |
EP0004898B1 (de) | 1982-04-07 |
IE48133B1 (en) | 1984-10-03 |
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