SU166341A1 - Method of producing complete esters of 0-dialkylaminoalkylpyridine phosphate acids - Google Patents
Method of producing complete esters of 0-dialkylaminoalkylpyridine phosphate acidsInfo
- Publication number
- SU166341A1 SU166341A1 SU873633A SU873633A SU166341A1 SU 166341 A1 SU166341 A1 SU 166341A1 SU 873633 A SU873633 A SU 873633A SU 873633 A SU873633 A SU 873633A SU 166341 A1 SU166341 A1 SU 166341A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- dialkylaminoalkylpyridine
- complete esters
- producing complete
- acids
- phosphate acids
- Prior art date
Links
- 150000002148 esters Chemical class 0.000 title description 2
- 125000002467 phosphate group Chemical class [H]OP(=O)(O[H])O[*] 0.000 title 1
- 239000002253 acid Substances 0.000 description 6
- 150000007513 acids Chemical class 0.000 description 4
- RTZKZFJDLAIYFH-UHFFFAOYSA-N diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 4
- 150000001875 compounds Chemical class 0.000 description 3
- PVWOIHVRPOBWPI-UHFFFAOYSA-N N-Propyl iodide Chemical compound CCCI PVWOIHVRPOBWPI-UHFFFAOYSA-N 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 150000002170 ethers Chemical class 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 150000004820 halides Chemical class 0.000 description 1
- 125000001475 halogen functional group Chemical group 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Description
Предложен способ получени полных эфиров о-диалкиламиноалкилтритиофосфорных кислот путем взаимодействи солей диалкиламиноалкилтритиофосфорных кислот с соединени ми , содержащими подвижный галоид, при иагревании до 35-60°С.A method for the preparation of the complete ethers of o-dialkylaminoalkyltrithiophosphoric acids by reacting the salts of dialkylaminoalkyltrithiophosphoric acids with compounds containing mobile halide, when heated to 35-60 ° C.
Предложенный способ и получаемые соединени вл ютс новым ч. Они могут быть использованы в качестве физиологически активных веществ.The proposed method and the resulting compounds are novel. They can be used as physiologically active substances.
Пример. К 13,4 г (1,04 моль) дикалиевой соли о-диалкиламиноалкилтритиофосфорной кислоты прибавл ют 27,2 г (0,16 моль) йодистого пропила. Смесь ;агревают с обратным холодильником при температуре 43- 45°С на прот женш 3-3,5 час. Осадок отфильтровывают и промывают абсолютпымExample. To 13.4 g (1.04 mol) of the di-potassium salt of o-dialkylaminoalkyltrithiophosphoric acid was added 27.2 g (0.16 mol) of propyl iodide. Mixture; heated under reflux at 43-45 ° C for 3-3.5 hours. The precipitate is filtered off and washed with an absolute
эфиром. Из фильтрата в вакууме водоструйного пасоса удал ют эфир и избыток йодистого пропила. Оставшеес подвижное масло разгон ют в высоком вакууме.by ether. The ether and excess propyl iodide are removed from the filtrate under vacuum of a water jet. The remaining mobile oil is dispersed under high vacuum.
Выход SiS-дипропилового эфира о-диэтиламинопропилтритиофосфорной кислоты 9 г (65,60/0 от теоретического), т. кип. 95°С (2- 10-3 мм рт. ст.); п 1,5284; d 2,0470.The yield of SiS-dipropyl ether o-diethylaminopropyltriophosphate acid 9 g (65.60 / 0 from the theoretical), t. Kip. 95 ° C (2-10-3 mm Hg. Art.); p 1,5284; d 2.0470.
Предмет изобретени Subject invention
Способ получени полых эфиров о-диалкиламиноалкилтритиофосфорных кислот, отличающийс тем, что соли диалкиламииоалкилтритиофосфорных кислот подвергают взаимодействию с соединени ми, содержащими подвижиый галоид, при нагревании до температуры .A process for the preparation of hollow esters of o-dialkylaminoalkyltrithiophosphoric acids, characterized in that the salts of dialkyl aminioalkyltrithiophosphoric acids are reacted with compounds containing mobile halo when heated to a temperature.
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU166341A1 true SU166341A1 (en) |
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