SU1415725A1 - 4-(4'-methoxyphenyl)-2-morpholinoethylthio-5-phenylimidazole dihydrochloride enhancing physical resistance - Google Patents

4-(4'-methoxyphenyl)-2-morpholinoethylthio-5-phenylimidazole dihydrochloride enhancing physical resistance

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Publication number
SU1415725A1
SU1415725A1 SU4181259/04A SU4181259A SU1415725A1 SU 1415725 A1 SU1415725 A1 SU 1415725A1 SU 4181259/04 A SU4181259/04 A SU 4181259/04A SU 4181259 A SU4181259 A SU 4181259A SU 1415725 A1 SU1415725 A1 SU 1415725A1
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SU
USSR - Soviet Union
Prior art keywords
phenylimidazole
methoxyphenyl
morpholinoethylthio
dihydrochloride
physical resistance
Prior art date
Application number
SU4181259/04A
Other languages
Russian (ru)
Inventor
В.М. Виноградов
А.Б. Томчин
Р.П. Спивакова
В.Ф. Катков
Original Assignee
В.М. Виноградов
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by В.М. Виноградов filed Critical В.М. Виноградов
Priority to SU4181259/04A priority Critical patent/SU1415725A1/en
Application granted granted Critical
Publication of SU1415725A1 publication Critical patent/SU1415725A1/en

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Abstract

FIELD: organic chemistry, imidazole derivatives. SUBSTANCE: product: 4-(4'-methoxyphenyl)-2-morpholinoethylthio-5-phenylimidazole. Synthesis is carried out by reaction of 2-mercapto-4-(4'-methoxyphenyl)-5-phenylimidazole with 2-morpholinoethyl bromide hydrobromide followed by conversion of obtained base to hydrochloride by treatment with HCl. Yield is 92%, m. p. is 155 C, empirical formula is CHClNOS.. Synthesized compound provides the best resistance at run as compared with control after 24 hr to 188%, toxicity LD= 575 mg/kg. EFFECT: synthesis of new substances showing enhanced activity. 1 tbl
SU4181259/04A 1986-11-17 1986-11-17 4-(4'-methoxyphenyl)-2-morpholinoethylthio-5-phenylimidazole dihydrochloride enhancing physical resistance SU1415725A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SU4181259/04A SU1415725A1 (en) 1986-11-17 1986-11-17 4-(4'-methoxyphenyl)-2-morpholinoethylthio-5-phenylimidazole dihydrochloride enhancing physical resistance

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU4181259/04A SU1415725A1 (en) 1986-11-17 1986-11-17 4-(4'-methoxyphenyl)-2-morpholinoethylthio-5-phenylimidazole dihydrochloride enhancing physical resistance

Publications (1)

Publication Number Publication Date
SU1415725A1 true SU1415725A1 (en) 1996-10-10

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ID=60536087

Family Applications (1)

Application Number Title Priority Date Filing Date
SU4181259/04A SU1415725A1 (en) 1986-11-17 1986-11-17 4-(4'-methoxyphenyl)-2-morpholinoethylthio-5-phenylimidazole dihydrochloride enhancing physical resistance

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SU (1) SU1415725A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7223781B2 (en) 2001-03-26 2007-05-29 Beiersdorf Ag 2-mercapto-4,5-diarylimidazole derivatives and the use thereof as cyclooxygenase inhibitors
US7582660B2 (en) 2002-08-20 2009-09-01 C-A-I-R Biosciences Gmbh 2-thio-substituted imidazole derivatives and their use in pharmaceutics

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7223781B2 (en) 2001-03-26 2007-05-29 Beiersdorf Ag 2-mercapto-4,5-diarylimidazole derivatives and the use thereof as cyclooxygenase inhibitors
US7582660B2 (en) 2002-08-20 2009-09-01 C-A-I-R Biosciences Gmbh 2-thio-substituted imidazole derivatives and their use in pharmaceutics

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