SMT201500183B - Derivato di chinone 2,3-dimetossi-5metil-6-(10-idrossidecil)-1,4-benzochinone per la cura della sclerosi multipla primaria progressiva - Google Patents

Derivato di chinone 2,3-dimetossi-5metil-6-(10-idrossidecil)-1,4-benzochinone per la cura della sclerosi multipla primaria progressiva

Info

Publication number
SMT201500183B
SMT201500183B SM201500183T SM201500183T SMT201500183B SM T201500183 B SMT201500183 B SM T201500183B SM 201500183 T SM201500183 T SM 201500183T SM 201500183 T SM201500183 T SM 201500183T SM T201500183 B SMT201500183 B SM T201500183B
Authority
SM
San Marino
Prior art keywords
5methyl
hydroxydecyl
quinone
dimethoxy
treatment
Prior art date
Application number
SM201500183T
Other languages
English (en)
Inventor
Thomas Meier
Bibiana Bielekova
Original Assignee
Santhera Pharmaceuticals Ch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santhera Pharmaceuticals Ch filed Critical Santhera Pharmaceuticals Ch
Publication of SMT201500183B publication Critical patent/SMT201500183B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SM201500183T 2009-04-30 2015-07-31 Derivato di chinone 2,3-dimetossi-5metil-6-(10-idrossidecil)-1,4-benzochinone per la cura della sclerosi multipla primaria progressiva SMT201500183B (it)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US17417009P 2009-04-30 2009-04-30
EP09006030A EP2246048A1 (en) 2009-04-30 2009-04-30 Quinone derivative 2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone for the treatment of primary progressive multiple sclerosis
PCT/EP2009/009148 WO2010124713A1 (en) 2009-04-30 2009-12-18 Quinone derivative 2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone for the treatment of primary progressive multiple sclerosis
EP09795720.3A EP2424513B1 (en) 2009-04-30 2009-12-18 Quinone derivative 2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone for the treatment of primary progressive multiple sclerosis

Publications (1)

Publication Number Publication Date
SMT201500183B true SMT201500183B (it) 2015-09-07

Family

ID=40874702

Family Applications (1)

Application Number Title Priority Date Filing Date
SM201500183T SMT201500183B (it) 2009-04-30 2015-07-31 Derivato di chinone 2,3-dimetossi-5metil-6-(10-idrossidecil)-1,4-benzochinone per la cura della sclerosi multipla primaria progressiva

Country Status (15)

Country Link
US (1) US8293800B2 (it)
EP (2) EP2246048A1 (it)
JP (1) JP2012525341A (it)
AU (1) AU2009345604B2 (it)
CA (1) CA2760338C (it)
DK (1) DK2424513T3 (it)
ES (1) ES2539602T3 (it)
HR (1) HRP20150723T1 (it)
HU (1) HUE027428T2 (it)
MX (1) MX2011011494A (it)
PL (1) PL2424513T3 (it)
PT (1) PT2424513E (it)
SI (1) SI2424513T1 (it)
SM (1) SMT201500183B (it)
WO (1) WO2010124713A1 (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2908929C (en) * 2012-07-12 2021-01-26 Concert Pharmaceuticals, Inc. Deuterated idebenone
EP3600553A4 (en) 2017-03-26 2020-09-02 Mapi Pharma Ltd. GLATIRAMER DEPOT SYSTEMS FOR TREATMENT OF PROGRESSIVE FORMS OF MULTIPLE SCLEROSIS
KR20220078644A (ko) 2019-10-04 2022-06-10 스텔스 바이오테라퓨틱스 인코포레이티드 미토콘드리아 질환 치료를 위한 바티퀴논의 퀴논-, 히드로퀴논- 및 나프토퀴논-유사체
EP4351545A1 (en) 2021-06-07 2024-04-17 Katholieke Universiteit Leuven Idebenone in the treatment of drug resistant epilepsy

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51128932A (en) 1975-04-30 1976-11-10 Takeda Chem Ind Ltd Organic compounds
JPH11116470A (ja) 1997-08-12 1999-04-27 Takeda Chem Ind Ltd イデベノン含有経皮投与製剤
WO1999007355A1 (fr) 1997-08-12 1999-02-18 Takeda Chemical Industries, Ltd. Preparation contenant de l'idebenone pour administration par voie percutanee
US6133322A (en) 1998-10-29 2000-10-17 Institut National De La Sante Et De La Recherche Medicale (Inserm) Quinone derivatives for treating or preventing diseases associated with iron overload
ES2345353T3 (es) 2005-03-21 2010-09-21 Santhera Pharmaceuticals (Schweiz) Ag Idebenona para el tratamiento de distrofias musculares.
EP1891946A1 (en) 2006-08-14 2008-02-27 Santhera Pharmaceuticals (Schweiz) AG Transmucosal administration of 2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone
US20100234402A1 (en) * 2007-05-31 2010-09-16 Gideon Dreyfuss Methods and compositions for treating spinal muscular atrophy
EP2352500A4 (en) * 2008-10-10 2012-04-25 Celtaxsys Inc METHOD FOR INDUCING NEGATIVE CHEMOTACTISM
US20100129431A1 (en) * 2008-11-24 2010-05-27 Alpharx Inc. Idebenone composition for the treatment of neurological disorders

Also Published As

Publication number Publication date
DK2424513T3 (en) 2015-08-24
EP2424513B1 (en) 2015-05-20
EP2424513A1 (en) 2012-03-07
HRP20150723T1 (en) 2015-11-06
AU2009345604A1 (en) 2011-11-17
EP2246048A1 (en) 2010-11-03
MX2011011494A (es) 2012-02-29
WO2010124713A1 (en) 2010-11-04
CA2760338A1 (en) 2010-11-04
PL2424513T3 (pl) 2015-10-30
CA2760338C (en) 2016-08-09
AU2009345604B2 (en) 2014-08-14
SI2424513T1 (sl) 2015-08-31
JP2012525341A (ja) 2012-10-22
ES2539602T3 (es) 2015-07-02
US8293800B2 (en) 2012-10-23
PT2424513E (pt) 2015-06-25
US20100280130A1 (en) 2010-11-04
HUE027428T2 (hu) 2016-10-28

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