SK283859B6 - 1-[2'-(Substituovaný)vinyl]-5H-2,3-benzodiazepínové deriváty, spôsob ich prípravy a medziprodukty na ich prípravu, liečivá ich obsahujúce a ich použitie - Google Patents

1-[2'-(Substituovaný)vinyl]-5H-2,3-benzodiazepínové deriváty, spôsob ich prípravy a medziprodukty na ich prípravu, liečivá ich obsahujúce a ich použitie Download PDF

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Publication number
SK283859B6
SK283859B6 SK167-96A SK16796A SK283859B6 SK 283859 B6 SK283859 B6 SK 283859B6 SK 16796 A SK16796 A SK 16796A SK 283859 B6 SK283859 B6 SK 283859B6
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SK
Slovakia
Prior art keywords
substituted
vinyl
group
benzodiazepine derivatives
benzodiazepine
Prior art date
Application number
SK167-96A
Other languages
English (en)
Slovak (sk)
Other versions
SK16796A3 (en
Inventor
Pál Vágó
József Reiter
István Gyertyán
István Gacsályi
András Bilkei-Gorzó
András Egyed
Ferenc Andrási
Anna Bakonyi
Pál Berzsenyi
Péter Botka (Zosnulý)
Tamás Hámori
Haskáné Cecilia Salamon
Edit Horváth
Katalin Horváth
Jenö Körösi (Zosnulý)
Györgyné Máté
Imre Moravcsik
Eszter Szentkuti
Gábor Zólyomi
Gábor Blaskó
Kazóné Klára Daróczi
Gyula Simig
Károly Tihanyi
Judit Bajnógel
Original Assignee
EGIS Gyógyszergyár Rt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU9500385A external-priority patent/HU224438B1/hu
Priority claimed from HU9503353A external-priority patent/HU221508B/hu
Application filed by EGIS Gyógyszergyár Rt. filed Critical EGIS Gyógyszergyár Rt.
Publication of SK16796A3 publication Critical patent/SK16796A3/sk
Publication of SK283859B6 publication Critical patent/SK283859B6/sk

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/02Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK167-96A 1995-02-09 1996-02-07 1-[2'-(Substituovaný)vinyl]-5H-2,3-benzodiazepínové deriváty, spôsob ich prípravy a medziprodukty na ich prípravu, liečivá ich obsahujúce a ich použitie SK283859B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU9500385A HU224438B1 (hu) 1995-02-09 1995-02-09 Benzodiazepin-származékok, eljárás előállításukra, alkalmazásuk és ezeket tartalmazó gyógyászati készítmények
HU9503353A HU221508B (en) 1995-11-24 1995-11-24 1-vinyl-5h-2,3-benzodiazepine derivatives, pharmaceutical compositions containing them, process for the preparation of the compounds and intermediates

Publications (2)

Publication Number Publication Date
SK16796A3 SK16796A3 (en) 1997-01-08
SK283859B6 true SK283859B6 (sk) 2004-03-02

Family

ID=26318220

Family Applications (1)

Application Number Title Priority Date Filing Date
SK167-96A SK283859B6 (sk) 1995-02-09 1996-02-07 1-[2'-(Substituovaný)vinyl]-5H-2,3-benzodiazepínové deriváty, spôsob ich prípravy a medziprodukty na ich prípravu, liečivá ich obsahujúce a ich použitie

Country Status (14)

Country Link
US (1) US5942506A (fi)
JP (1) JP3128750B2 (fi)
KR (1) KR100330658B1 (fi)
BE (1) BE1009516A3 (fi)
CA (1) CA2169115C (fi)
CZ (1) CZ291833B6 (fi)
FI (1) FI960615A (fi)
FR (1) FR2730489B1 (fi)
GB (1) GB2297750B (fi)
HR (1) HRP960064A2 (fi)
PL (1) PL191032B1 (fi)
RU (1) RU2161607C2 (fi)
SK (1) SK283859B6 (fi)
YU (1) YU8296A (fi)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE761315A (fi) * 1970-01-12 1971-07-07 S M B Anciens Etablissements J
HU179018B (en) * 1978-10-19 1982-08-28 Gyogyszerkutato Intezet Process for producing new 5h-2,3-benzodiazepine derivatives
HU186760B (en) * 1981-03-12 1985-09-30 Gyogyszerkutato Intezet Process for preparing 3,4-dihydro-5h-2,3-aenzodiazepine derivatives
HU195788B (en) * 1986-05-21 1988-07-28 Gyogyszerkutato Intezet Process for producing 1-/hydroxy-stiryl/-5h-2,3-benzobiazepines and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
GB2297750A (en) 1996-08-14
FR2730489A1 (fr) 1996-08-14
RU2161607C2 (ru) 2001-01-10
CA2169115A1 (en) 1996-08-10
YU8296A (sh) 1999-03-04
CZ37896A3 (en) 1996-08-14
BE1009516A3 (fr) 1997-04-01
CA2169115C (en) 2000-07-25
SK16796A3 (en) 1997-01-08
GB9602703D0 (en) 1996-04-10
FR2730489B1 (fr) 1997-04-11
HRP960064A2 (en) 1997-10-31
KR960031443A (ko) 1996-09-17
PL312706A1 (en) 1996-08-19
US5942506A (en) 1999-08-24
CZ291833B6 (cs) 2003-06-18
FI960615A0 (fi) 1996-02-09
JP3128750B2 (ja) 2001-01-29
KR100330658B1 (ko) 2002-11-07
GB2297750B (en) 1998-07-01
PL191032B1 (pl) 2006-03-31
FI960615A (fi) 1996-08-10
JPH08295676A (ja) 1996-11-12

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