SK165596A3 - Sterol derivatives used for regulation of meiosis in the mammalian zygotes - Google Patents

Sterol derivatives used for regulation of meiosis in the mammalian zygotes Download PDF

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Publication number
SK165596A3
SK165596A3 SK1655-96A SK165596A SK165596A3 SK 165596 A3 SK165596 A3 SK 165596A3 SK 165596 A SK165596 A SK 165596A SK 165596 A3 SK165596 A3 SK 165596A3
Authority
SK
Slovakia
Prior art keywords
formula
group
sterol derivatives
carbon atoms
miosis
Prior art date
Application number
SK1655-96A
Other languages
English (en)
Slovak (sk)
Inventor
Anne G Byskov
Claus Y Andersen
Lars Nordholm
Henning Thogersen
Ole Wassmann
Ivan V Diers
Erling Guddal
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of SK165596A3 publication Critical patent/SK165596A3/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/001—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class spiro-linked
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Steroid Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SK1655-96A 1994-06-23 1995-06-23 Sterol derivatives used for regulation of meiosis in the mammalian zygotes SK165596A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK75394 1994-06-23
DK24195 1995-03-09
PCT/DK1995/000265 WO1996000235A1 (en) 1994-06-23 1995-06-23 Sterol derivatives used for regulation of meiosis

Publications (1)

Publication Number Publication Date
SK165596A3 true SK165596A3 (en) 1997-08-06

Family

ID=26063596

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1655-96A SK165596A3 (en) 1994-06-23 1995-06-23 Sterol derivatives used for regulation of meiosis in the mammalian zygotes

Country Status (26)

Country Link
US (1) US5716777A (fi)
EP (1) EP0767798B1 (fi)
JP (1) JP3987105B2 (fi)
KR (1) KR100408369B1 (fi)
CN (1) CN1068333C (fi)
AT (1) ATE248852T1 (fi)
AU (1) AU694240B2 (fi)
BG (1) BG101067A (fi)
BR (1) BR9508074A (fi)
CA (1) CA2192941C (fi)
CZ (1) CZ289407B6 (fi)
DE (1) DE69531682T2 (fi)
DK (1) DK0767798T3 (fi)
ES (1) ES2204955T3 (fi)
FI (1) FI117159B (fi)
HU (1) HUT76343A (fi)
IL (1) IL114294A (fi)
IS (1) IS4404A (fi)
MX (1) MX9700174A (fi)
NO (1) NO314534B1 (fi)
PL (1) PL186688B1 (fi)
RU (1) RU2194510C2 (fi)
SI (1) SI9520077A (fi)
SK (1) SK165596A3 (fi)
UA (1) UA51622C2 (fi)
WO (1) WO1996000235A1 (fi)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP9800731A3 (en) * 1995-03-06 2000-03-28 Novo Nordisk As Stimulation of meiosis
HUP9900454A3 (en) * 1995-06-23 1999-11-29 Novo Nordisk As Meiosis regulating compounds and their use
US6645953B2 (en) * 1995-06-23 2003-11-11 Novo Nordisk A/S Meiosis regulating compounds
WO1997000883A1 (en) * 1995-06-23 1997-01-09 Novo Nordisk A/S Meiosis regulating compounds
WO1998028323A1 (en) 1996-12-20 1998-07-02 Novo Nordisk A/S Meiosis regulating compounds
ATE229032T1 (de) * 1997-05-16 2002-12-15 Akzo Nobel Nv 20-aralkyl-5,alpha,-pregnan derivate
AU8535398A (en) * 1997-06-04 1998-12-21 Akzo Nobel N.V. 17beta-allyloxy(thio)alkyl-androstane derivatives for the modulation of meiosis
ATE220686T1 (de) * 1997-12-18 2002-08-15 Akzo Nobel Nv 17beta-aryl(arylmethyl)oxy(thio)alkyl- androstanderivative
AU3701199A (en) * 1998-05-13 1999-11-29 Novo Nordisk A/S Meiosis regulating compounds
IL139241A0 (en) * 1998-05-13 2001-11-25 Novo Nordisk As Meiosis regulating compounds
AU5408999A (en) * 1998-05-26 1999-12-13 Schering Aktiengesellschaft Treatment of infertility with camp-increasing compounds alone or in combination with at least one meiosis-stimulating compound
KR20010053031A (ko) * 1998-06-19 2001-06-25 한센 핀 베네드, 안네 제헤르, 웨이콥 마리안느 감수분열 조절 화합물
AU759344B2 (en) * 1998-12-11 2003-04-10 Akzo Nobel N.V. 22S-hydroxycholesta-8, 14-diene derivatives with meiosis regulating activity
WO2000036132A1 (en) * 1998-12-14 2000-06-22 Merck & Co., Inc. Hiv integrase inhibitors
IL143735A0 (en) * 1999-02-10 2002-04-21 Schering Ag Unsaturated cholestane derivatives and their use for the preparation of meiosis regulating medicaments
ATE361091T1 (de) * 1999-02-24 2007-05-15 Novo Nordisk As Behandlung von unfruchtbarkeit
JP2002537349A (ja) * 1999-02-24 2002-11-05 ノボ ノルディスク アクティーゼルスカブ 不妊症の治療
EP1157096A2 (en) * 1999-02-26 2001-11-28 Novo Nordisk A/S Culture medium comprising meiosis activating sterols (mas) and method for invitro fertilisation
AU3285000A (en) * 1999-03-09 2000-09-28 Akzo Nobel N.V. 22r-hydroxycholesta-8,14-diene derivatives for the inhibition of meiosis
BR0014058A (pt) * 1999-09-16 2004-03-30 Novo Nordisk As Produto sólido, composição, solução aquosa de 4,4-dimetil-5a-colesta-8,14,24-triene-3(beta) -ol, e, dispositivo tendo uma concavidade
EP1127890A1 (en) 2000-02-22 2001-08-29 Schering Aktiengesellschaft Steroid derivatives with an additional ring annulated to ring A and use of these derivatives for the preparation of meiosis regulating medicaments
CA2399036A1 (en) * 2000-02-25 2001-08-30 Schering Aktiengesellschaft Improvement of implantation rate
AU3376501A (en) * 2000-02-25 2001-09-03 Novo Nordisk A/S Improvement of implantation rate
CA2404822A1 (en) * 2000-05-18 2001-11-22 Schering Aktiengesellschaft Fertilization of aged oocytes
EP1245572A1 (en) 2001-03-26 2002-10-02 Schering Aktiengesellschaft Aminosterol compounds, their use in the preparation of meiosis-regulating medicaments and method for their preparation
AU2003203145A1 (en) * 2002-02-22 2003-09-09 Novo Nordisk A/S A transducer of mas signalling
US9376462B2 (en) 2010-10-01 2016-06-28 Indiana University Research And Technology Corporation Process for preparing delta-7,9(11) steroids from Ganoderma lucidum and analogs thereof
US9165822B2 (en) 2013-03-11 2015-10-20 Taiwan Semiconductor Manufacturing Company, Ltd. Semiconductor devices and methods of forming same
EA024619B1 (ru) * 2014-11-21 2016-10-31 Эльвин Гаджи оглы Керимли ФРАКСИНОСТЕРИН - 24β-ЭТИЛХОЛЕСТА-20-КАРБОКСИ-6(7),8(9)-ДИЕН 3β-ОЛА И ЕГО ПРОИЗВОДНОЕ

Also Published As

Publication number Publication date
ATE248852T1 (de) 2003-09-15
CN1151164A (zh) 1997-06-04
CZ289407B6 (cs) 2002-01-16
HU9603584D0 (en) 1997-02-28
UA51622C2 (uk) 2002-12-16
PL186688B1 (pl) 2004-02-27
KR100408369B1 (ko) 2004-04-28
BG101067A (en) 1997-08-29
CA2192941A1 (en) 1996-01-04
JPH10502060A (ja) 1998-02-24
DE69531682T2 (de) 2004-07-15
IL114294A (en) 2002-09-12
NO965516D0 (no) 1996-12-20
IL114294A0 (en) 1995-10-31
AU2734395A (en) 1996-01-19
RU2194510C2 (ru) 2002-12-20
EP0767798B1 (en) 2003-09-03
CA2192941C (en) 2009-04-14
CN1068333C (zh) 2001-07-11
BR9508074A (pt) 1997-08-12
FI117159B (fi) 2006-07-14
DE69531682D1 (de) 2003-10-09
HUT76343A (en) 1997-08-28
ES2204955T3 (es) 2004-05-01
SI9520077A (sl) 1998-06-30
AU694240B2 (en) 1998-07-16
NO965516L (no) 1997-02-21
EP0767798A1 (en) 1997-04-16
FI965144A0 (fi) 1996-12-20
CZ372596A3 (en) 1997-07-16
FI965144A (fi) 1997-02-20
DK0767798T3 (da) 2003-12-22
IS4404A (is) 1996-12-23
PL317830A1 (en) 1997-04-28
MX9700174A (es) 1997-04-30
NO314534B1 (no) 2003-04-07
WO1996000235A1 (en) 1996-01-04
US5716777A (en) 1998-02-10
JP3987105B2 (ja) 2007-10-03

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