SK133799A3 - Oil-in-water emulsions for reconstituting lamellarity of the lipid structure of damaged skin - Google Patents

Oil-in-water emulsions for reconstituting lamellarity of the lipid structure of damaged skin Download PDF

Info

Publication number: SK133799A3
Authority: SK; Slovakia
Prior art keywords: oil; emulsifier; lipophilic; lipid; fatty
Prior art date: 1997-04-03

Application number

SK1337-99A

Other languages

English (en)

Slovak (sk)

Inventor

Pascal Bordat

Stefanie Ortanderl

Martina Kampmann

Marianne Waldmann-Laue

Georg Knubel

Marcus Mausberg

Original Assignee

Henkel Kgaa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-03

Filing date

1997-11-28

Publication date

2000-02-14

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7825359&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK133799(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1997-11-28 Application filed by Henkel Kgaa filed Critical Henkel Kgaa

2000-02-14 Publication of SK133799A3 publication Critical patent/SK133799A3/sk

Links

239000000839 emulsion Substances 0.000 title abstract description 20
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title abstract description 19
125000003473 lipid group Chemical group 0.000 title 1
239000003995 emulsifying agent Substances 0.000 claims abstract description 25
150000002632 lipids Chemical class 0.000 claims abstract description 18
239000007957 coemulsifier Substances 0.000 claims abstract description 17
125000004432 carbon atom Chemical group C* 0.000 claims abstract description 14
239000002537 cosmetic Substances 0.000 claims abstract description 13
NOPFSRXAKWQILS-UHFFFAOYSA-N docosan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCCCO NOPFSRXAKWQILS-UHFFFAOYSA-N 0.000 claims abstract description 13
125000000217 alkyl group Chemical group 0.000 claims abstract description 12
125000003342 alkenyl group Chemical group 0.000 claims abstract description 10
239000004973 liquid crystal related substance Substances 0.000 claims abstract description 8
125000002252 acyl group Chemical group 0.000 claims abstract description 7
239000001257 hydrogen Substances 0.000 claims abstract description 7
229910052739 hydrogen Inorganic materials 0.000 claims abstract description 7
229960000735 docosanol Drugs 0.000 claims abstract description 5
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims abstract 3
239000012071 phase Substances 0.000 claims description 31
239000007764 o/w emulsion Substances 0.000 claims description 9
239000008346 aqueous phase Substances 0.000 claims description 7
238000000034 method Methods 0.000 claims description 2
239000012875 nonionic emulsifier Substances 0.000 claims description 2
150000002431 hydrogen Chemical class 0.000 claims 1
239000004615 ingredient Substances 0.000 claims 1
125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
239000003921 oil Substances 0.000 description 30
235000019198 oils Nutrition 0.000 description 30
-1 sucrose fatty acid esters Chemical class 0.000 description 19
239000000194 fatty acid Substances 0.000 description 16
235000014113 dietary fatty acids Nutrition 0.000 description 15
229930195729 fatty acid Natural products 0.000 description 15
239000006071 cream Substances 0.000 description 12
210000003491 skin Anatomy 0.000 description 10
239000000203 mixture Substances 0.000 description 9
150000004665 fatty acids Chemical class 0.000 description 8
239000004094 surface-active agent Substances 0.000 description 7
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 6
238000004519 manufacturing process Methods 0.000 description 6
239000007788 liquid Substances 0.000 description 5
239000002304 perfume Substances 0.000 description 5
239000001993 wax Substances 0.000 description 5
239000000230 xanthan gum Substances 0.000 description 5
229920001285 xanthan gum Polymers 0.000 description 5
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235000010493 xanthan gum Nutrition 0.000 description 5
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239000008168 almond oil Substances 0.000 description 4
150000002148 esters Chemical class 0.000 description 4
150000002191 fatty alcohols Chemical class 0.000 description 4
125000004079 stearyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 4
150000003626 triacylglycerols Chemical class 0.000 description 4
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
239000005662 Paraffin oil Substances 0.000 description 3
NWGKJDSIEKMTRX-BFWOXRRGSA-N [(2r)-2-[(3r,4s)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl] (z)-octadec-9-enoate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)C1OC[C@H](O)[C@H]1O NWGKJDSIEKMTRX-BFWOXRRGSA-N 0.000 description 3
KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
239000010374 citricidal Substances 0.000 description 3
UKMSUNONTOPOIO-UHFFFAOYSA-N docosanoic acid Chemical compound CCCCCCCCCCCCCCCCCCCCCC(O)=O UKMSUNONTOPOIO-UHFFFAOYSA-N 0.000 description 3
239000008103 glucose Substances 0.000 description 3
235000011187 glycerol Nutrition 0.000 description 3
125000004435 hydrogen atom Chemical class [H]* 0.000 description 3
125000002887 hydroxy group Chemical group [H]O* 0.000 description 3
125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 3
238000005259 measurement Methods 0.000 description 3
125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 3
239000003755 preservative agent Substances 0.000 description 3
210000000434 stratum corneum Anatomy 0.000 description 3
229940042585 tocopherol acetate Drugs 0.000 description 3
JNYAEWCLZODPBN-JGWLITMVSA-N (2r,3r,4s)-2-[(1r)-1,2-dihydroxyethyl]oxolane-3,4-diol Chemical compound OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O JNYAEWCLZODPBN-JGWLITMVSA-N 0.000 description 2
SSCYWBFGEPBPAK-UHFFFAOYSA-N 2,2,3,3,4,4-hexamethyldecane Chemical compound CCCCCCC(C)(C)C(C)(C)C(C)(C)C SSCYWBFGEPBPAK-UHFFFAOYSA-N 0.000 description 2
KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 2
FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 2
FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 2
IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 2
TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 description 2
OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 description 2
241001465754 Metazoa Species 0.000 description 2
HPEUJPJOZXNMSJ-UHFFFAOYSA-N Methyl stearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC HPEUJPJOZXNMSJ-UHFFFAOYSA-N 0.000 description 2
KWIUHFFTVRNATP-UHFFFAOYSA-O N,N,N-trimethylglycinium Chemical compound C[N+](C)(C)CC(O)=O KWIUHFFTVRNATP-UHFFFAOYSA-O 0.000 description 2
NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
235000019486 Sunflower oil Nutrition 0.000 description 2
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
239000002253 acid Substances 0.000 description 2
239000004480 active ingredient Substances 0.000 description 2
239000002280 amphoteric surfactant Substances 0.000 description 2
125000000129 anionic group Chemical group 0.000 description 2
235000013871 bee wax Nutrition 0.000 description 2
239000012166 beeswax Substances 0.000 description 2
WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 2
229960003237 betaine Drugs 0.000 description 2
229910052799 carbon Inorganic materials 0.000 description 2
125000002091 cationic group Chemical group 0.000 description 2
239000013078 crystal Substances 0.000 description 2
230000000694 effects Effects 0.000 description 2
238000004945 emulsification Methods 0.000 description 2
235000008524 evening primrose extract Nutrition 0.000 description 2
229940089020 evening primrose oil Drugs 0.000 description 2
239000010475 evening primrose oil Substances 0.000 description 2
239000012530 fluid Substances 0.000 description 2
210000000245 forearm Anatomy 0.000 description 2
IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 2
BTFJIXJJCSYFAL-UHFFFAOYSA-N icosan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCO BTFJIXJJCSYFAL-UHFFFAOYSA-N 0.000 description 2
229940093629 isopropyl isostearate Drugs 0.000 description 2
XUGNVMKQXJXZCD-UHFFFAOYSA-N isopropyl palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC(C)C XUGNVMKQXJXZCD-UHFFFAOYSA-N 0.000 description 2
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 2
239000002736 nonionic surfactant Substances 0.000 description 2
239000000546 pharmaceutical excipient Substances 0.000 description 2
229920000728 polyester Polymers 0.000 description 2
229920000223 polyglycerol Chemical class 0.000 description 2
229920005862 polyol Polymers 0.000 description 2
150000003077 polyols Chemical class 0.000 description 2
229920006395 saturated elastomer Polymers 0.000 description 2
239000000600 sorbitol Substances 0.000 description 2
238000003756 stirring Methods 0.000 description 2
238000003860 storage Methods 0.000 description 2
239000000126 substance Substances 0.000 description 2
239000002600 sunflower oil Substances 0.000 description 2
239000003760 tallow Substances 0.000 description 2
239000002562 thickening agent Substances 0.000 description 2
239000002888 zwitterionic surfactant Substances 0.000 description 2
WTVHAMTYZJGJLJ-UHFFFAOYSA-N (+)-(4S,8R)-8-epi-beta-bisabolol Natural products CC(C)=CCCC(C)C1(O)CCC(C)=CC1 WTVHAMTYZJGJLJ-UHFFFAOYSA-N 0.000 description 1
RGZSQWQPBWRIAQ-CABCVRRESA-N (-)-alpha-Bisabolol Chemical compound CC(C)=CCC[C@](C)(O)[C@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-CABCVRRESA-N 0.000 description 1
CFOQKXQWGLAKSK-KTKRTIGZSA-N (13Z)-docosen-1-ol Chemical compound CCCCCCCC\C=C/CCCCCCCCCCCCO CFOQKXQWGLAKSK-KTKRTIGZSA-N 0.000 description 1
NKJOXAZJBOMXID-UHFFFAOYSA-N 1,1'-Oxybisoctane Chemical compound CCCCCCCCOCCCCCCCC NKJOXAZJBOMXID-UHFFFAOYSA-N 0.000 description 1
UKIARGZKGOGJNE-UHFFFAOYSA-N 1-(16-methylheptadecanoyloxy)butyl 16-methylheptadecanoate Chemical compound CC(C)CCCCCCCCCCCCCCC(=O)OC(CCC)OC(=O)CCCCCCCCCCCCCCC(C)C UKIARGZKGOGJNE-UHFFFAOYSA-N 0.000 description 1
CFOQKXQWGLAKSK-UHFFFAOYSA-N 13-docosen-1-ol Natural products CCCCCCCCC=CCCCCCCCCCCCCO CFOQKXQWGLAKSK-UHFFFAOYSA-N 0.000 description 1
DHGISFWHDBPFBJ-UHFFFAOYSA-N 2-(11-methyldodecanoyloxy)ethyl 11-methyldodecanoate Chemical compound CC(C)CCCCCCCCCC(=O)OCCOC(=O)CCCCCCCCCC(C)C DHGISFWHDBPFBJ-UHFFFAOYSA-N 0.000 description 1
RYKSMKFLIHUEBL-UHFFFAOYSA-N 2-(2-ethylhexanoyloxy)propyl 2-ethylhexanoate Chemical compound CCCCC(CC)C(=O)OCC(C)OC(=O)C(CC)CCCC RYKSMKFLIHUEBL-UHFFFAOYSA-N 0.000 description 1
NDHKAEBPGBKCIO-UHFFFAOYSA-N 2-(hexadecylamino)propanoic acid Chemical compound CCCCCCCCCCCCCCCCNC(C)C(O)=O NDHKAEBPGBKCIO-UHFFFAOYSA-N 0.000 description 1
QVRMIJZFODZFNE-UHFFFAOYSA-N 2-[dimethyl-[3-(octadecanoylamino)propyl]azaniumyl]acetate Chemical compound CCCCCCCCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC([O-])=O QVRMIJZFODZFNE-UHFFFAOYSA-N 0.000 description 1
DHVLDKHFGIVEIP-UHFFFAOYSA-N 2-bromo-2-(bromomethyl)pentanedinitrile Chemical compound BrCC(Br)(C#N)CCC#N DHVLDKHFGIVEIP-UHFFFAOYSA-N 0.000 description 1
LWLRMRFJCCMNML-UHFFFAOYSA-N 2-ethylhexyl dodecanoate Chemical compound CCCCCCCCCCCC(=O)OCC(CC)CCCC LWLRMRFJCCMNML-UHFFFAOYSA-N 0.000 description 1
SFAAOBGYWOUHLU-UHFFFAOYSA-N 2-ethylhexyl hexadecanoate Chemical compound CCCCCCCCCCCCCCCC(=O)OCC(CC)CCCC SFAAOBGYWOUHLU-UHFFFAOYSA-N 0.000 description 1
MWKPHOIHTLQZIY-UHFFFAOYSA-N 2-hexyldecyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(CCCCCC)CCCCCCCC MWKPHOIHTLQZIY-UHFFFAOYSA-N 0.000 description 1
QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 description 1
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RMTFNDVZYPHUEF-XZBKPIIZSA-N 3-O-methyl-D-glucose Chemical compound O=C[C@H](O)[C@@H](OC)[C@H](O)[C@H](O)CO RMTFNDVZYPHUEF-XZBKPIIZSA-N 0.000 description 1
HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 description 1
SJIDAAGFCNIAJP-UHFFFAOYSA-N 6-methylheptyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCCCCC(C)C SJIDAAGFCNIAJP-UHFFFAOYSA-N 0.000 description 1
UBGYURICIGUKHC-UHFFFAOYSA-N 7-methyloctyl hexadecanoate Chemical compound CCCCCCCCCCCCCCCC(=O)OCCCCCCC(C)C UBGYURICIGUKHC-UHFFFAOYSA-N 0.000 description 1
244000144725 Amygdalus communis Species 0.000 description 1
235000011437 Amygdalus communis Nutrition 0.000 description 1
235000021357 Behenic acid Nutrition 0.000 description 1
DPUOLQHDNGRHBS-UHFFFAOYSA-N Brassidinsaeure Natural products CCCCCCCCC=CCCCCCCCCCCCC(O)=O DPUOLQHDNGRHBS-UHFFFAOYSA-N 0.000 description 1
KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 1
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AXGRCZMRSSHAML-UHFFFAOYSA-N Euxyl K 400 Chemical compound CC(O)Oc1ccccc1.CC(O)Oc1ccccc1.CC(O)Oc1ccccc1.CC(O)Oc1ccccc1.BrCC(Br)(CCC#N)C#N AXGRCZMRSSHAML-UHFFFAOYSA-N 0.000 description 1
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239000004471 Glycine Substances 0.000 description 1
CMBYOWLFQAFZCP-UHFFFAOYSA-N Hexyl dodecanoate Chemical compound CCCCCCCCCCCC(=O)OCCCCCC CMBYOWLFQAFZCP-UHFFFAOYSA-N 0.000 description 1
238000004566 IR spectroscopy Methods 0.000 description 1
241000446313 Lamella Species 0.000 description 1
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TXZRBCSUYLEATA-GALHSAGASA-N [(z)-docos-13-enyl] (z)-octadec-9-enoate Chemical compound CCCCCCCC\C=C/CCCCCCCCCCCCOC(=O)CCCCCCC\C=C/CCCCCCCC TXZRBCSUYLEATA-GALHSAGASA-N 0.000 description 1
150000007513 acids Chemical class 0.000 description 1
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238000009472 formulation Methods 0.000 description 1
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230000034659 glycolysis Effects 0.000 description 1
229940107702 grapefruit seed extract Drugs 0.000 description 1
XXMIOPMDWAUFGU-UHFFFAOYSA-N hexane-1,6-diol Chemical compound OCCCCCCO XXMIOPMDWAUFGU-UHFFFAOYSA-N 0.000 description 1
210000000003 hoof Anatomy 0.000 description 1
229910052500 inorganic mineral Inorganic materials 0.000 description 1
229940100554 isononyl isononanoate Drugs 0.000 description 1
229940089456 isopropyl stearate Drugs 0.000 description 1
229940119170 jojoba wax Drugs 0.000 description 1
229910001629 magnesium chloride Inorganic materials 0.000 description 1
230000014759 maintenance of location Effects 0.000 description 1
239000012528 membrane Substances 0.000 description 1
QYDYPVFESGNLHU-KHPPLWFESA-N methyl oleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC QYDYPVFESGNLHU-KHPPLWFESA-N 0.000 description 1
229940073769 methyl oleate Drugs 0.000 description 1
239000011707 mineral Substances 0.000 description 1
238000002156 mixing Methods 0.000 description 1
WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
SLCVBVWXLSEKPL-UHFFFAOYSA-N neopentyl glycol Chemical compound OCC(C)(C)CO SLCVBVWXLSEKPL-UHFFFAOYSA-N 0.000 description 1
WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 1
235000021313 oleic acid Nutrition 0.000 description 1
150000002889 oleic acids Chemical class 0.000 description 1
239000004006 olive oil Substances 0.000 description 1
235000008390 olive oil Nutrition 0.000 description 1
239000003346 palm kernel oil Substances 0.000 description 1
235000019865 palm kernel oil Nutrition 0.000 description 1
239000002540 palm oil Substances 0.000 description 1
239000010690 paraffinic oil Substances 0.000 description 1
239000000312 peanut oil Substances 0.000 description 1
230000035515 penetration Effects 0.000 description 1
WXZMFSXDPGVJKK-UHFFFAOYSA-N pentaerythritol Chemical compound OCC(CO)(CO)CO WXZMFSXDPGVJKK-UHFFFAOYSA-N 0.000 description 1
229960005323 phenoxyethanol Drugs 0.000 description 1
229920000435 poly(dimethylsiloxane) Polymers 0.000 description 1
229920001281 polyalkylene Polymers 0.000 description 1
229920000098 polyolefin Polymers 0.000 description 1
229920001296 polysiloxane Polymers 0.000 description 1
PZQSQRCNMZGWFT-QXMHVHEDSA-N propan-2-yl (z)-octadec-9-enoate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC(C)C PZQSQRCNMZGWFT-QXMHVHEDSA-N 0.000 description 1
NEOZOXKVMDBOSG-UHFFFAOYSA-N propan-2-yl 16-methylheptadecanoate Chemical compound CC(C)CCCCCCCCCCCCCCC(=O)OC(C)C NEOZOXKVMDBOSG-UHFFFAOYSA-N 0.000 description 1
ZPWFUIUNWDIYCJ-UHFFFAOYSA-N propan-2-yl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC(C)C ZPWFUIUNWDIYCJ-UHFFFAOYSA-N 0.000 description 1
150000003839 salts Chemical class 0.000 description 1
235000003441 saturated fatty acids Nutrition 0.000 description 1
210000000582 semen Anatomy 0.000 description 1
229920002545 silicone oil Polymers 0.000 description 1
230000008591 skin barrier function Effects 0.000 description 1
230000037380 skin damage Effects 0.000 description 1
239000000243 solution Substances 0.000 description 1
239000001587 sorbitan monostearate Substances 0.000 description 1
235000011076 sorbitan monostearate Nutrition 0.000 description 1
229940035048 sorbitan monostearate Drugs 0.000 description 1
239000003549 soybean oil Substances 0.000 description 1
235000012424 soybean oil Nutrition 0.000 description 1
239000005720 sucrose Substances 0.000 description 1
150000005846 sugar alcohols Polymers 0.000 description 1
BDHFUVZGWQCTTF-UHFFFAOYSA-N sulfonic acid Chemical compound OS(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-N 0.000 description 1
238000010998 test method Methods 0.000 description 1
229960001295 tocopherol Drugs 0.000 description 1
229930003799 tocopherol Natural products 0.000 description 1
235000010384 tocopherol Nutrition 0.000 description 1
239000011732 tocopherol Substances 0.000 description 1
235000021122 unsaturated fatty acids Nutrition 0.000 description 1
150000004670 unsaturated fatty acids Chemical class 0.000 description 1
235000015112 vegetable and seed oil Nutrition 0.000 description 1
235000019871 vegetable fat Nutrition 0.000 description 1
239000008158 vegetable oil Substances 0.000 description 1
235000013311 vegetables Nutrition 0.000 description 1
239000007762 w/o emulsion Substances 0.000 description 1
239000002569 water oil cream Substances 0.000 description 1
235000019386 wax ester Nutrition 0.000 description 1
GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
- A61K8/062—Oil-in-water emulsions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0295—Liquid crystals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1274—Non-vesicle bilayer structures, e.g. liquid crystals, tubules, cubic phases, cochleates; Sponge phases
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Dispersion Chemistry (AREA)
Birds (AREA)
Crystallography & Structural Chemistry (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Dermatology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Cosmetics (AREA)
Colloid Chemistry (AREA)

SK1337-99A 1997-04-03 1997-11-28 Oil-in-water emulsions for reconstituting lamellarity of the lipid structure of damaged skin SK133799A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19713793A DE19713793A1 (de)	1997-04-03	1997-04-03	Öl-in-Wasser-Emulsionen zur Wiederherstellung der Lamellarität der Lipidstruktur geschädigter Haut
PCT/EP1997/006639 WO1998044896A1 (fr)	1997-04-03	1997-11-28	Emulsions huile dans l'eau pour la restitution de la lamellarite de la structure lipidique de la peau endommagee

Publications (1)

Publication Number	Publication Date
SK133799A3 true SK133799A3 (en)	2000-02-14

Family

ID=7825359

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK1337-99A SK133799A3 (en)	1997-04-03	1997-11-28	Oil-in-water emulsions for reconstituting lamellarity of the lipid structure of damaged skin

Country Status (13)

Country	Link
US (1)	US6379681B1 (fr)
EP (1)	EP0973484B1 (fr)
JP (1)	JP2001518886A (fr)
CN (1)	CN1248904A (fr)
AT (1)	ATE270537T1 (fr)
CA (1)	CA2285216A1 (fr)
DE (2)	DE19713793A1 (fr)
ES (1)	ES2226010T3 (fr)
HU (1)	HUP0000501A3 (fr)
NO (1)	NO994786L (fr)
PL (1)	PL335902A1 (fr)
SK (1)	SK133799A3 (fr)
WO (1)	WO1998044896A1 (fr)

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DE19857349A1 (de) *	1998-12-11	2000-06-15	Wolfgang Schnizer	Hautpflege-System
FR2816852B1 (fr) *	2000-11-21	2005-08-26	Nuxe Lab	Association stabilisee d'un colorant et d'un emulsionnant, composition cosmetique et/ou dermatologique la contenant et procede de preparation
JP2002265347A (ja) *	2001-03-13	2002-09-18	Shiseido Co Ltd	コーニファイドエンベロープの成熟を促す化粧料
US6608011B2 (en)	2001-06-11	2003-08-19	Colgate-Palmolive Company	Shampoos with behenyl-alcohol
US7758636B2 (en) *	2002-09-20	2010-07-20	Innovational Holdings Llc	Expandable medical device with openings for delivery of multiple beneficial agents
CN100455193C (zh) *	2003-03-11	2009-01-28	科宁公司	用作农用化学品佐剂的微乳液
JP4592347B2 (ja) *	2003-07-14	2010-12-01	株式会社ヤクルト本社	外用剤組成物
WO2005046633A1 (fr) *	2003-11-04	2005-05-26	The Procter & Gamble Company	Compositions nettoyantes pour le corps
CN1874749A (zh)	2003-11-04	2006-12-06	宝洁公司	包含残留谐香剂的芳香剂
GB0403879D0 (en) *	2004-02-21	2004-03-24	Unilever Plc	Hair conditioning compositions and methods of manufacture
JP4854194B2 (ja) *	2004-07-05	2012-01-18	株式会社ファンケル	ラメラ構造再生剤及び皮膚外用剤
WO2006018149A1 (fr) *	2004-08-13	2006-02-23	Henkel Kommanditgesellschaft Auf Aktien	Compositions cosmetiques pour traiter une peau stressee contenant de la taurine et des alcools gras a chaine longue
DE102005063178A1 (de) *	2005-12-30	2007-07-05	Henkel Kgaa	Kosmetische Lichtschutzzusammensetzungen auf der Basis lamellarer Emulsionen
DE102006015544A1 (de) *	2006-03-31	2007-10-04	Kuhs Gmbh	Topisch zu applizierende Zusammensetzung
GB0714817D0 (en) *	2007-07-31	2007-09-12	Croda Int Plc	Polyglycerol derivatives
DE102010046931A1 (de) *	2010-09-29	2012-03-29	Sanderstrothmann Gmbh	Verfahren zur Herstellung eines kosmetischen Mittels
FR2991171B1 (fr)	2012-06-01	2014-05-23	Galderma Res & Dev	Procede de preparation d'une composition dermatologique comprenant des oleosomes
DE102013217316A1 (de) *	2013-08-30	2015-03-05	Henkel Ag & Co. Kgaa	Hautpflegeöl
CA3019865C (fr)	2016-04-21	2024-03-19	Unilever Plc	Procede de production d'emulsions de fines gouttelettes a basse pression
US11744783B2 (en)	2016-04-21	2023-09-05	Conopco, Inc.	Nanoemulsions comprising fatty acid and n-acyl derivatives of amino acid salt
KR20190095338A (ko) *	2016-12-13	2019-08-14	바스프 에스이	텍스쳐화된 조성물
US20200375854A1 (en) *	2019-05-31	2020-12-03	L'oreal	Compositions and methods for treating keratinous substrates
CN113476346A (zh) *	2021-06-16	2021-10-08	西安德诺海思医疗科技有限公司	一种皮肤屏障修复组合物

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US4400295A (en) *	1979-03-24	1983-08-23	Loire Cosmetics Co., Ltd.	Emulsifier composition
JPS61158909A (ja) *	1984-12-29	1986-07-18	Pola Chem Ind Inc	パツク料
US4767625A (en)	1985-09-02	1988-08-30	Kao Corporation	Lamella type single phase liquid crystal composition and oil-base cosmetic compositions using the same
GB8724254D0 (en)	1987-10-15	1987-11-18	Unilever Plc	Hair treatment product
GB9302492D0 (en)	1993-02-09	1993-03-24	Procter & Gamble	Cosmetic compositions
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FR2709666B1 (fr)	1993-09-07	1995-10-13	Oreal	Composition cosmétique ou dermatologique constituée d'une émulsion huile dans eau à base de globules huileux pourvus d'un enrobage cristal liquide lamellaire.
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JPH08337513A (ja) *	1995-06-13	1996-12-24	Shiseido Co Ltd	撥水性水中油型乳化組成物
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JP3549336B2 (ja) *	1995-10-12	2004-08-04	株式会社資生堂	水中油型乳化組成物
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1997
- 1997-04-03 DE DE19713793A patent/DE19713793A1/de not_active Withdrawn
- 1997-11-28 EP EP97953710A patent/EP0973484B1/fr not_active Revoked
- 1997-11-28 HU HU0000501A patent/HUP0000501A3/hu unknown
- 1997-11-28 DE DE59711769T patent/DE59711769D1/de not_active Expired - Lifetime
- 1997-11-28 US US09/402,301 patent/US6379681B1/en not_active Expired - Lifetime
- 1997-11-28 CN CN97182084A patent/CN1248904A/zh active Pending
- 1997-11-28 WO PCT/EP1997/006639 patent/WO1998044896A1/fr active IP Right Grant
- 1997-11-28 ES ES97953710T patent/ES2226010T3/es not_active Expired - Lifetime
- 1997-11-28 JP JP54228598A patent/JP2001518886A/ja not_active Ceased
- 1997-11-28 PL PL97335902A patent/PL335902A1/xx unknown
- 1997-11-28 CA CA002285216A patent/CA2285216A1/fr not_active Abandoned
- 1997-11-28 SK SK1337-99A patent/SK133799A3/sk unknown
- 1997-11-28 AT AT97953710T patent/ATE270537T1/de not_active IP Right Cessation
1999
- 1999-10-01 NO NO994786A patent/NO994786L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP0973484A1 (fr)	2000-01-26
EP0973484B1 (fr)	2004-07-07
NO994786D0 (no)	1999-10-01
CA2285216A1 (fr)	1998-10-15
HUP0000501A2 (en)	2000-07-28
HUP0000501A3 (en)	2001-11-28
JP2001518886A (ja)	2001-10-16
DE19713793A1 (de)	1998-10-08
ATE270537T1 (de)	2004-07-15
ES2226010T3 (es)	2005-03-16
DE59711769D1 (de)	2004-08-12
CN1248904A (zh)	2000-03-29
US6379681B1 (en)	2002-04-30
PL335902A1 (en)	2000-05-22
WO1998044896A1 (fr)	1998-10-15
NO994786L (no)	1999-10-01

Publication	Publication Date	Title
SK133799A3 (en)	2000-02-14	Oil-in-water emulsions for reconstituting lamellarity of the lipid structure of damaged skin
JP3043410B2 (ja)	2000-05-22	水中油型エマルジョン
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EP1762216B1 (fr)	2016-04-20	Préparation cosmétique
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WO2016091939A1 (fr)	2016-06-16	Composition comportant de l'hespérétine, une huile, au moins un ester d'acide gras de (poly)glycérol et un polyol
KR20180123685A (ko)	2018-11-19	이중상 메이크업 제거용 조성물
EA004662B1 (ru)	2004-06-24	Масла для кожи, образующие пузырьки и содержащие водно-масляные эмульгаторы с гидрофильно-липофильным балансом 2-6, способ получения и применение
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DE19916090A1 (de)	2000-10-12	Hautpflegemittel
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JP2001233754A (ja)	2001-08-28	乳化型皮膚外用剤
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JP2007077077A (ja)	2007-03-29	水中油型マイクロエマルション及びその製造方法
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