SI2914264T1 - 6-okso-1,6-dihidro-piridazinski derivat za uporabo za zdravljenje hepatocelularnega karcinoma (hcc) - Google Patents

6-okso-1,6-dihidro-piridazinski derivat za uporabo za zdravljenje hepatocelularnega karcinoma (hcc)

Info

Publication number
SI2914264T1
SI2914264T1 SI201330832T SI201330832T SI2914264T1 SI 2914264 T1 SI2914264 T1 SI 2914264T1 SI 201330832 T SI201330832 T SI 201330832T SI 201330832 T SI201330832 T SI 201330832T SI 2914264 T1 SI2914264 T1 SI 2914264T1
Authority
SI
Slovenia
Prior art keywords
hcc
dihydro
oxo
treatment
hepatocellular carcinoma
Prior art date
Application number
SI201330832T
Other languages
English (en)
Inventor
Manja Friese-Hamim
Friedhelm Bladt
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of SI2914264T1 publication Critical patent/SI2914264T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
SI201330832T 2012-11-02 2013-10-04 6-okso-1,6-dihidro-piridazinski derivat za uporabo za zdravljenje hepatocelularnega karcinoma (hcc) SI2914264T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12007494 2012-11-02
PCT/EP2013/002998 WO2014067610A1 (en) 2012-11-02 2013-10-04 A 6-oxo-1,6-dihydro-pyridazine derivative for the use for the treatment of hepatocellular carcinoma (hcc)
EP13776720.8A EP2914264B1 (en) 2012-11-02 2013-10-04 A 6-oxo-1,6-dihydro-pyridazine derivative for the use for the treatment of hepatocellular carcinoma (hcc)

Publications (1)

Publication Number Publication Date
SI2914264T1 true SI2914264T1 (sl) 2017-12-29

Family

ID=47143496

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201330832T SI2914264T1 (sl) 2012-11-02 2013-10-04 6-okso-1,6-dihidro-piridazinski derivat za uporabo za zdravljenje hepatocelularnega karcinoma (hcc)

Country Status (26)

Country Link
US (1) US20150283137A1 (sl)
EP (1) EP2914264B1 (sl)
JP (1) JP6255028B2 (sl)
KR (1) KR102131588B1 (sl)
CN (1) CN104768553A (sl)
AR (1) AR093318A1 (sl)
AU (1) AU2013339823B2 (sl)
BR (1) BR112015008279A2 (sl)
CA (1) CA2890273C (sl)
DK (1) DK2914264T3 (sl)
ES (1) ES2646913T3 (sl)
HK (1) HK1211869A1 (sl)
HR (1) HRP20171295T1 (sl)
HU (1) HUE035483T2 (sl)
IL (1) IL238536B (sl)
LT (1) LT2914264T (sl)
MX (1) MX354518B (sl)
NO (1) NO2914264T3 (sl)
PL (1) PL2914264T3 (sl)
PT (1) PT2914264T (sl)
RS (1) RS56485B1 (sl)
RU (1) RU2650679C2 (sl)
SG (1) SG11201503214YA (sl)
SI (1) SI2914264T1 (sl)
WO (1) WO2014067610A1 (sl)
ZA (1) ZA201503924B (sl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105792641A (zh) 2013-08-14 2016-07-20 有限会社日本通商 水栽培***、和设置有水栽培***的植物工厂以及由发泡聚苯乙烯泡沫制成的温室
CA3146384A1 (en) * 2019-07-10 2021-01-14 Merck Patent Gmbh Pharmaceutical preparation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005057924A1 (de) * 2005-12-05 2007-06-06 Merck Patent Gmbh Pyridazinonderivate
DE102007032507A1 (de) * 2007-07-12 2009-04-02 Merck Patent Gmbh Pyridazinonderivate
SG10201504735QA (en) * 2009-01-08 2015-07-30 Merck Patent Gmbh Novel polymorphic forms of 3-(1-{3-[5-(1-methyl-piperidin-4ylmethoxy)-pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydro-pyridazin-3-yl)-benzonitrile hydrochloride salt and processes of manufacturing thereof

Also Published As

Publication number Publication date
NO2914264T3 (sl) 2018-01-06
MX354518B (es) 2018-03-08
CN104768553A (zh) 2015-07-08
RU2650679C2 (ru) 2018-04-17
EP2914264A1 (en) 2015-09-09
US20150283137A1 (en) 2015-10-08
LT2914264T (lt) 2017-11-10
BR112015008279A2 (pt) 2017-07-04
JP2015536957A (ja) 2015-12-24
CA2890273C (en) 2021-10-26
WO2014067610A1 (en) 2014-05-08
HUE035483T2 (hu) 2018-05-02
IL238536A0 (en) 2015-06-30
EP2914264B1 (en) 2017-08-09
JP6255028B2 (ja) 2017-12-27
MX2015005265A (es) 2015-07-17
PL2914264T3 (pl) 2017-12-29
ES2646913T3 (es) 2017-12-18
RU2015120692A (ru) 2016-12-27
SG11201503214YA (en) 2015-05-28
DK2914264T3 (en) 2017-09-11
HRP20171295T1 (hr) 2017-10-20
KR102131588B1 (ko) 2020-07-08
ZA201503924B (en) 2020-11-25
AU2013339823B2 (en) 2018-01-04
PT2914264T (pt) 2017-11-14
HK1211869A1 (en) 2016-06-03
AR093318A1 (es) 2015-05-27
RS56485B1 (sr) 2018-01-31
KR20150079942A (ko) 2015-07-08
AU2013339823A1 (en) 2015-06-18
IL238536B (en) 2019-01-31
CA2890273A1 (en) 2014-05-08

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