SI2727588T1 - Na baklofenu in akamprosatu temelječa terapija nevroloških motenj - Google Patents

Na baklofenu in akamprosatu temelječa terapija nevroloških motenj

Info

Publication number
SI2727588T1
SI2727588T1 SI201231471T SI201231471T SI2727588T1 SI 2727588 T1 SI2727588 T1 SI 2727588T1 SI 201231471 T SI201231471 T SI 201231471T SI 201231471 T SI201231471 T SI 201231471T SI 2727588 T1 SI2727588 T1 SI 2727588T1
Authority
SI
Slovenia
Prior art keywords
baclofen
neurological disorders
based therapy
acamprosate
acamprosate based
Prior art date
Application number
SI201231471T
Other languages
English (en)
Inventor
Daniel Cohen
Ilya Chumakov
Serguei Nabirochkin
Emmanuel Vial
Mickael Guedj
Original Assignee
Pharnext
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharnext filed Critical Pharnext
Publication of SI2727588T1 publication Critical patent/SI2727588T1/sl

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/145Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
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    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/164Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
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    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
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    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
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    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
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    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
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  • Physiology (AREA)
  • Psychology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SI201231471T 2011-03-01 2012-03-01 Na baklofenu in akamprosatu temelječa terapija nevroloških motenj SI2727588T1 (sl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP11305217 2011-03-01
US201161468658P 2011-03-29 2011-03-29
US201161493606P 2011-06-06 2011-06-06
EP11305687 2011-06-06
EP13196461.1A EP2727588B1 (en) 2011-03-01 2012-03-01 Baclofen and acamprosate based therapy of neurological disorders

Publications (1)

Publication Number Publication Date
SI2727588T1 true SI2727588T1 (sl) 2019-03-29

Family

ID=46758335

Family Applications (3)

Application Number Title Priority Date Filing Date
SI201230019T SI2560631T1 (sl) 2011-03-01 2012-03-01 Na baklofenu in akamprosatu temeljeäśa terapija nevroloĺ kih nepravilnosti
SI201231317T SI2796132T1 (sl) 2011-03-01 2012-03-01 Terapija nevroloških motenj, ki temelji na baklofenu in akamprozatu
SI201231471T SI2727588T1 (sl) 2011-03-01 2012-03-01 Na baklofenu in akamprosatu temelječa terapija nevroloških motenj

Family Applications Before (2)

Application Number Title Priority Date Filing Date
SI201230019T SI2560631T1 (sl) 2011-03-01 2012-03-01 Na baklofenu in akamprosatu temeljeäśa terapija nevroloĺ kih nepravilnosti
SI201231317T SI2796132T1 (sl) 2011-03-01 2012-03-01 Terapija nevroloških motenj, ki temelji na baklofenu in akamprozatu

Country Status (27)

Country Link
US (7) US9820978B2 (sl)
EP (5) EP2727588B1 (sl)
JP (2) JP5987008B2 (sl)
KR (2) KR101918745B1 (sl)
CN (2) CN103596562B (sl)
AU (2) AU2012222351B2 (sl)
BR (1) BR112013022112B1 (sl)
CA (1) CA2828765C (sl)
CY (3) CY1115074T1 (sl)
DK (3) DK2727588T3 (sl)
EA (2) EA023277B1 (sl)
ES (5) ES2698927T3 (sl)
HK (2) HK1182615A1 (sl)
HR (1) HRP20140131T1 (sl)
HU (1) HUE038653T2 (sl)
IL (2) IL228177B (sl)
LT (2) LT2727588T (sl)
MX (1) MX340568B (sl)
PL (3) PL2560631T3 (sl)
PT (1) PT2560631E (sl)
RS (3) RS58114B1 (sl)
SG (2) SG192968A1 (sl)
SI (3) SI2560631T1 (sl)
SM (1) SMT201400029B (sl)
TR (1) TR201809351T4 (sl)
WO (2) WO2012117075A2 (sl)
ZA (1) ZA201306039B (sl)

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US9387206B2 (en) 2009-11-03 2016-07-12 Pharnext Therapeutic approaches for treating Alzheimer's disease
US10010515B2 (en) 2011-03-01 2018-07-03 Pharnext Therapeutic approaches for treating Parkinson's disease
US9248111B2 (en) 2011-03-01 2016-02-02 Pharnext Therapeutic approaches for treating parkinson's disease
PL2560631T3 (pl) 2011-03-01 2014-06-30 Pharnext Terapia zaburzeń neurologicznych oparta na baklofenie i akamprozacie
US9241933B2 (en) 2011-03-01 2016-01-26 Pharnext Compositions for treating amyotrophic lateral sclerosis
UA115968C2 (uk) * 2011-03-01 2018-01-25 Фарнекст Нові композиції для лікування неврологічних захворювань
CN108057033A (zh) * 2011-03-01 2018-05-22 法耐斯特公司 用于治疗肌萎缩性侧索硬化症的新组合物
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US9867837B2 (en) 2011-03-01 2018-01-16 Pharnext Compositions for treating neurological disorders
US9931326B2 (en) 2011-03-29 2018-04-03 Pharnext Composition comprising torasemide and baclofen for treating neurological disorders
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AU2013224959B2 (en) * 2012-03-01 2017-12-07 Pharnext New compositions for treating amyotrophic lateral sclerosis
US9545389B2 (en) * 2012-07-18 2017-01-17 Pharnext Baclofen and acamprosate based therapy of macular degeneration disorders
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GB201300684D0 (en) 2013-01-15 2013-02-27 Apitope Int Nv Peptide
UA114811C2 (uk) * 2013-02-28 2017-08-10 Фарнекст Застосування акампросату та баклофену для лікування аміотрофічного бічного склерозу
BR112015030268B1 (pt) 2013-06-05 2023-01-31 Pharnext Composição farmacêutica
JP6476174B2 (ja) 2013-06-19 2019-02-27 ソム イノヴェーション バイオテック、ソシエダッド リミターダ 運動過剰障害の予防および/または治療における使用のための治療剤
KR102206745B1 (ko) * 2013-07-12 2021-02-03 경상대학교산학협력단 안토시아닌 및 gabab 수용체 작용제를 유효성분으로 포함하는 신경질환 치료제
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