SI2727588T1 - Na baklofenu in akamprosatu temelječa terapija nevroloških motenj - Google Patents
Na baklofenu in akamprosatu temelječa terapija nevroloških motenjInfo
- Publication number
- SI2727588T1 SI2727588T1 SI201231471T SI201231471T SI2727588T1 SI 2727588 T1 SI2727588 T1 SI 2727588T1 SI 201231471 T SI201231471 T SI 201231471T SI 201231471 T SI201231471 T SI 201231471T SI 2727588 T1 SI2727588 T1 SI 2727588T1
- Authority
- SI
- Slovenia
- Prior art keywords
- baclofen
- neurological disorders
- based therapy
- acamprosate
- acamprosate based
- Prior art date
Links
- KPYSYYIEGFHWSV-UHFFFAOYSA-N Baclofen Chemical compound OC(=O)CC(CN)C1=CC=C(Cl)C=C1 KPYSYYIEGFHWSV-UHFFFAOYSA-N 0.000 title 1
- 208000012902 Nervous system disease Diseases 0.000 title 1
- 208000025966 Neurological disease Diseases 0.000 title 1
- AFCGFAGUEYAMAO-UHFFFAOYSA-N acamprosate Chemical compound CC(=O)NCCCS(O)(=O)=O AFCGFAGUEYAMAO-UHFFFAOYSA-N 0.000 title 1
- 229960004047 acamprosate Drugs 0.000 title 1
- 229960000794 baclofen Drugs 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
Classifications
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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- A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
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- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
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- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Psychology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP11305217 | 2011-03-01 | ||
US201161468658P | 2011-03-29 | 2011-03-29 | |
US201161493606P | 2011-06-06 | 2011-06-06 | |
EP11305687 | 2011-06-06 | ||
EP13196461.1A EP2727588B1 (en) | 2011-03-01 | 2012-03-01 | Baclofen and acamprosate based therapy of neurological disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
SI2727588T1 true SI2727588T1 (sl) | 2019-03-29 |
Family
ID=46758335
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201230019T SI2560631T1 (sl) | 2011-03-01 | 2012-03-01 | Na baklofenu in akamprosatu temeljeäśa terapija nevroloĺ kih nepravilnosti |
SI201231317T SI2796132T1 (sl) | 2011-03-01 | 2012-03-01 | Terapija nevroloških motenj, ki temelji na baklofenu in akamprozatu |
SI201231471T SI2727588T1 (sl) | 2011-03-01 | 2012-03-01 | Na baklofenu in akamprosatu temelječa terapija nevroloških motenj |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201230019T SI2560631T1 (sl) | 2011-03-01 | 2012-03-01 | Na baklofenu in akamprosatu temeljeäśa terapija nevroloĺ kih nepravilnosti |
SI201231317T SI2796132T1 (sl) | 2011-03-01 | 2012-03-01 | Terapija nevroloških motenj, ki temelji na baklofenu in akamprozatu |
Country Status (27)
Country | Link |
---|---|
US (7) | US9820978B2 (sl) |
EP (5) | EP2727588B1 (sl) |
JP (2) | JP5987008B2 (sl) |
KR (2) | KR101918745B1 (sl) |
CN (2) | CN103596562B (sl) |
AU (2) | AU2012222351B2 (sl) |
BR (1) | BR112013022112B1 (sl) |
CA (1) | CA2828765C (sl) |
CY (3) | CY1115074T1 (sl) |
DK (3) | DK2727588T3 (sl) |
EA (2) | EA023277B1 (sl) |
ES (5) | ES2698927T3 (sl) |
HK (2) | HK1182615A1 (sl) |
HR (1) | HRP20140131T1 (sl) |
HU (1) | HUE038653T2 (sl) |
IL (2) | IL228177B (sl) |
LT (2) | LT2727588T (sl) |
MX (1) | MX340568B (sl) |
PL (3) | PL2560631T3 (sl) |
PT (1) | PT2560631E (sl) |
RS (3) | RS58114B1 (sl) |
SG (2) | SG192968A1 (sl) |
SI (3) | SI2560631T1 (sl) |
SM (1) | SMT201400029B (sl) |
TR (1) | TR201809351T4 (sl) |
WO (2) | WO2012117075A2 (sl) |
ZA (1) | ZA201306039B (sl) |
Families Citing this family (40)
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EP2065038A1 (en) | 2007-11-30 | 2009-06-03 | Pharnext | New therapeutic approaches for treating Charcot-Marie-Tooth disease |
EP2135607A1 (en) | 2008-06-18 | 2009-12-23 | Pharnext | Combination of pilocarpin and methimazol for treating Charcot-MarieTooth disease and related disorders |
EP2263665A1 (en) | 2009-06-02 | 2010-12-22 | Pharnext | New compositions for treating CMT and related disorders |
US9393241B2 (en) | 2009-06-02 | 2016-07-19 | Pharnext | Compositions for treating CMT and related disorders |
EP2322163A1 (en) | 2009-11-03 | 2011-05-18 | Pharnext | New therapeutics approaches for treating alzheimer disease |
US9387206B2 (en) | 2009-11-03 | 2016-07-12 | Pharnext | Therapeutic approaches for treating Alzheimer's disease |
US10010515B2 (en) | 2011-03-01 | 2018-07-03 | Pharnext | Therapeutic approaches for treating Parkinson's disease |
US9248111B2 (en) | 2011-03-01 | 2016-02-02 | Pharnext | Therapeutic approaches for treating parkinson's disease |
PL2560631T3 (pl) | 2011-03-01 | 2014-06-30 | Pharnext | Terapia zaburzeń neurologicznych oparta na baklofenie i akamprozacie |
US9241933B2 (en) | 2011-03-01 | 2016-01-26 | Pharnext | Compositions for treating amyotrophic lateral sclerosis |
UA115968C2 (uk) * | 2011-03-01 | 2018-01-25 | Фарнекст | Нові композиції для лікування неврологічних захворювань |
CN108057033A (zh) * | 2011-03-01 | 2018-05-22 | 法耐斯特公司 | 用于治疗肌萎缩性侧索硬化症的新组合物 |
EP2705842A1 (en) * | 2012-09-05 | 2014-03-12 | Pharnext | Therapeutic approaches for treating parkinson's disease |
US9867837B2 (en) | 2011-03-01 | 2018-01-16 | Pharnext | Compositions for treating neurological disorders |
US9931326B2 (en) | 2011-03-29 | 2018-04-03 | Pharnext | Composition comprising torasemide and baclofen for treating neurological disorders |
GB2501457A (en) | 2012-02-10 | 2013-10-30 | Rational Intellectual Holdings Ltd | Assigning player positions in an online table game |
AU2013224959B2 (en) * | 2012-03-01 | 2017-12-07 | Pharnext | New compositions for treating amyotrophic lateral sclerosis |
US9545389B2 (en) * | 2012-07-18 | 2017-01-17 | Pharnext | Baclofen and acamprosate based therapy of macular degeneration disorders |
EP2705841A1 (en) * | 2012-09-05 | 2014-03-12 | Pharnext | Combinations of nootropic agents for treating cognitive dysfunctions |
GB201300684D0 (en) | 2013-01-15 | 2013-02-27 | Apitope Int Nv | Peptide |
UA114811C2 (uk) * | 2013-02-28 | 2017-08-10 | Фарнекст | Застосування акампросату та баклофену для лікування аміотрофічного бічного склерозу |
BR112015030268B1 (pt) | 2013-06-05 | 2023-01-31 | Pharnext | Composição farmacêutica |
JP6476174B2 (ja) | 2013-06-19 | 2019-02-27 | ソム イノヴェーション バイオテック、ソシエダッド リミターダ | 運動過剰障害の予防および/または治療における使用のための治療剤 |
KR102206745B1 (ko) * | 2013-07-12 | 2021-02-03 | 경상대학교산학협력단 | 안토시아닌 및 gabab 수용체 작용제를 유효성분으로 포함하는 신경질환 치료제 |
WO2015023830A1 (en) | 2013-08-14 | 2015-02-19 | Stc.Unm | Treatment and prevention of stroke and other neurological disorders |
WO2015063140A1 (en) * | 2013-10-30 | 2015-05-07 | Pharnext | Compositions, methods and uses for the treatment of diabetes and related conditions by controlling blood glucose level |
EA201691602A1 (ru) * | 2014-02-11 | 2017-03-31 | Фарнекст | Комбинация баклофена, акампросата и среднецепочечных триглицеридов для лечения неврологических расстройств |
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