SI2714676T1 - Postopek za pripravo polimorfne oblike I etorikoksiba - Google Patents

Postopek za pripravo polimorfne oblike I etorikoksiba

Info

Publication number
SI2714676T1
SI2714676T1 SI201231601T SI201231601T SI2714676T1 SI 2714676 T1 SI2714676 T1 SI 2714676T1 SI 201231601 T SI201231601 T SI 201231601T SI 201231601 T SI201231601 T SI 201231601T SI 2714676 T1 SI2714676 T1 SI 2714676T1
Authority
SI
Slovenia
Prior art keywords
etoricoxib
preparation
polymorphic form
polymorphic
Prior art date
Application number
SI201231601T
Other languages
English (en)
Inventor
Alen Kljajic
Silvo Zupancic
Miha Vrbinc
Sabina Trost
Original Assignee
Farma Grs, D.O.O.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farma Grs, D.O.O. filed Critical Farma Grs, D.O.O.
Publication of SI2714676T1 publication Critical patent/SI2714676T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
SI201231601T 2011-05-27 2012-05-25 Postopek za pripravo polimorfne oblike I etorikoksiba SI2714676T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SI201100190 2011-05-27
PCT/EP2012/059852 WO2012163839A1 (en) 2011-05-27 2012-05-25 A process for the preparation of polymorphic form i of etoricoxib
EP12723214.8A EP2714676B1 (en) 2011-05-27 2012-05-25 A process for the preparation of polymorphic form i of etoricoxib

Publications (1)

Publication Number Publication Date
SI2714676T1 true SI2714676T1 (sl) 2019-06-28

Family

ID=46148892

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201231601T SI2714676T1 (sl) 2011-05-27 2012-05-25 Postopek za pripravo polimorfne oblike I etorikoksiba

Country Status (5)

Country Link
EP (1) EP2714676B1 (sl)
EA (1) EA023286B1 (sl)
PL (1) PL2714676T3 (sl)
SI (1) SI2714676T1 (sl)
WO (1) WO2012163839A1 (sl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013144977A2 (en) * 2012-03-30 2013-10-03 Mylan Laboratories Ltd. An improved process for the preparation of etoricoxib
WO2014041558A2 (en) * 2012-08-27 2014-03-20 Glenmark Pharmaceuticals Limited; Glenmark Generics Limited Process for preparation of crystalline etoricoxib
WO2014033526A1 (en) * 2012-08-27 2014-03-06 Cadila Healthcare Limited Pharmaceutical compositions of etoricoxib
EP3179987A1 (en) * 2014-07-31 2017-06-21 KRKA, d.d., Novo mesto Pharmaceutical composition of etoricoxib
CN105250231B (zh) * 2015-11-02 2020-05-12 北京泰德制药股份有限公司 一种含有依托考昔的药物组合物及其制备方法
CN111410629A (zh) * 2020-03-31 2020-07-14 天津大学 依托考昔溶剂化物及其制备方法
CN112321493A (zh) * 2020-10-28 2021-02-05 四川尚锐生物医药有限公司 一种依托考昔的纯化方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2260016C (en) 1996-07-18 2004-03-09 Merck Frosst Canada Inc. Substituted pyridines as selective cyclooxygenase-2 inhibitors
US5861419A (en) 1996-07-18 1999-01-19 Merck Frosst Canad, Inc. Substituted pyridines as selective cyclooxygenase-2 inhibitors
CA2329193C (en) 1998-04-24 2007-01-23 Merck & Co., Inc. Process for synthesizing cox-2 inhibitors
ATE320809T1 (de) 1999-11-29 2006-04-15 Merck Frosst Canada Inc Polymorphe, amorphe und hydratisierte formen von 5-chlor-3-(methansulfonylphenyl)-6'-methyl-2, 3')bipyridinyl
PH12001001175B1 (en) 2000-05-26 2006-08-10 Merck Sharp & Dohme 5-chloro-3-(4-methanesulfonylphenyl)-6'-methyl- (2,3')bipyridinyl in pure crystalline form and process for synthesis
US6521642B2 (en) * 2000-05-26 2003-02-18 Merck & Co., Inc. 5-chloro-3-(4-methanesulfonylphenyl)-6′-methyl-[2,3′]bipyridinyl in pure crystalline form and process for synthesis
WO2005085199A1 (en) 2004-01-14 2005-09-15 Cadila Healthcare Limited Novel polymorphs of etoricoxib
DK2401253T3 (en) * 2009-02-27 2016-04-18 Cadila Healthcare Ltd Method for producing etoricoxib

Also Published As

Publication number Publication date
EA201391721A1 (ru) 2014-03-31
WO2012163839A1 (en) 2012-12-06
EP2714676B1 (en) 2019-04-24
EP2714676A1 (en) 2014-04-09
PL2714676T3 (pl) 2019-10-31
EA023286B1 (ru) 2016-05-31

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