SI2640842T1 - Postopki in sestavki za induciranje imunskega odziva na EGFRvIII - Google Patents
Postopki in sestavki za induciranje imunskega odziva na EGFRvIIIInfo
- Publication number
- SI2640842T1 SI2640842T1 SI201131548T SI201131548T SI2640842T1 SI 2640842 T1 SI2640842 T1 SI 2640842T1 SI 201131548 T SI201131548 T SI 201131548T SI 201131548 T SI201131548 T SI 201131548T SI 2640842 T1 SI2640842 T1 SI 2640842T1
- Authority
- SI
- Slovenia
- Prior art keywords
- egfrviii
- inducing
- compositions
- methods
- immune response
- Prior art date
Links
- 230000028993 immune response Effects 0.000 title 1
- 230000001939 inductive effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001102—Receptors, cell surface antigens or cell surface determinants
- A61K39/001103—Receptors for growth factors
- A61K39/001104—Epidermal growth factor receptors [EGFR]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Cell Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41485010P | 2010-11-17 | 2010-11-17 | |
EP11841347.5A EP2640842B1 (en) | 2010-11-17 | 2011-11-17 | Methods and compositions for inducing an immune response to egfrviii |
PCT/US2011/061164 WO2012068360A1 (en) | 2010-11-17 | 2011-11-17 | Methods and compositions for inducing an immune response to egfrviii |
Publications (1)
Publication Number | Publication Date |
---|---|
SI2640842T1 true SI2640842T1 (sl) | 2018-09-28 |
Family
ID=46084412
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201131548T SI2640842T1 (sl) | 2010-11-17 | 2011-11-17 | Postopki in sestavki za induciranje imunskega odziva na EGFRvIII |
Country Status (16)
Country | Link |
---|---|
US (3) | US9200057B2 (sl) |
EP (1) | EP2640842B1 (sl) |
JP (1) | JP5998370B2 (sl) |
CN (1) | CN103415620B (sl) |
CA (1) | CA2818353A1 (sl) |
CY (1) | CY1120622T1 (sl) |
DK (1) | DK2640842T3 (sl) |
ES (1) | ES2684684T3 (sl) |
HR (1) | HRP20181343T1 (sl) |
HU (1) | HUE039747T2 (sl) |
LT (1) | LT2640842T (sl) |
PL (1) | PL2640842T3 (sl) |
PT (1) | PT2640842T (sl) |
RS (1) | RS57630B1 (sl) |
SI (1) | SI2640842T1 (sl) |
WO (1) | WO2012068360A1 (sl) |
Families Citing this family (39)
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WO2012019168A2 (en) | 2010-08-06 | 2012-02-09 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
CA2821992A1 (en) | 2010-10-01 | 2012-04-05 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
WO2012068360A1 (en) * | 2010-11-17 | 2012-05-24 | Aduro Biotech | Methods and compositions for inducing an immune response to egfrviii |
CA2831613A1 (en) | 2011-03-31 | 2012-10-04 | Moderna Therapeutics, Inc. | Delivery and formulation of engineered nucleic acids |
US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
ES2911677T3 (es) | 2011-10-03 | 2022-05-20 | Modernatx Inc | Nucleósidos, nucleótidos y ácidos nucleicos modificados, y sus usos |
DE12858350T1 (de) | 2011-12-16 | 2021-10-07 | Modernatx, Inc. | Modifizierte mrna zusammensetzungen |
EP3501550A1 (en) | 2012-04-02 | 2019-06-26 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins associated with human disease |
US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
US10501512B2 (en) | 2012-04-02 | 2019-12-10 | Modernatx, Inc. | Modified polynucleotides |
US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
US9770467B2 (en) | 2012-06-08 | 2017-09-26 | Aduro Biotech, Inc. | Compositions and methods for cancer immunotherapy |
SG10201610161UA (en) | 2012-11-06 | 2017-01-27 | Aduro Biotech Inc | Facultatively attenuated bacterial species and methods of preparation and use thereof |
US9597380B2 (en) | 2012-11-26 | 2017-03-21 | Modernatx, Inc. | Terminally modified RNA |
US9695212B2 (en) | 2012-12-13 | 2017-07-04 | Aduro Biotech, Inc. | Compositions comprising cyclic purine dinucleotides having defined stereochemistries and methods for their preparation and use |
CN104955835B (zh) | 2012-12-27 | 2020-04-17 | 艾杜罗生物科技公司 | 促进抗原序列的李斯特菌表达的信号肽融合配偶体以及其制备和使用方法 |
US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
US20140329889A1 (en) | 2013-05-03 | 2014-11-06 | The Regents Of The University Of California | Cyclic di-nucleotide induction of type i interferon |
CU24377B1 (es) | 2013-05-18 | 2018-12-05 | Aduro Biotech Inc | Dinucléotidos de purina cíclicos y composiciones de los mismos útiles para inducir la producción de interferón de tipo i dependientes de sting |
US9549944B2 (en) | 2013-05-18 | 2017-01-24 | Aduro Biotech, Inc. | Compositions and methods for inhibiting “stimulator of interferon gene”—dependent signalling |
US10023626B2 (en) | 2013-09-30 | 2018-07-17 | Modernatx, Inc. | Polynucleotides encoding immune modulating polypeptides |
EP3052521A1 (en) | 2013-10-03 | 2016-08-10 | Moderna Therapeutics, Inc. | Polynucleotides encoding low density lipoprotein receptor |
WO2015164121A1 (en) * | 2014-04-24 | 2015-10-29 | Advaxis, Inc. | Recombinant listeria vaccine strains and methods of producing the same |
WO2016061115A1 (en) | 2014-10-13 | 2016-04-21 | Providence Health & Services-Oregon D/B/A Providence Portland Medical Center | Bacterial vaccines deficient in the 2-c-methyl-d-erythritol-4-phosphate pathway and methods of preparation and use thereof |
MX2017004729A (es) * | 2014-10-14 | 2018-01-09 | Univ Pennsylvania | Terapia de combinacion para usar en la terapia contra el cancer. |
WO2016073381A1 (en) | 2014-11-03 | 2016-05-12 | Cerus Corporation | Compositions and methods for improved car-t cell therapies |
JP6692826B2 (ja) | 2015-03-10 | 2020-05-13 | アドゥロ バイオテック,インク. | 「インターフェロン遺伝子刺激因子」依存性シグナル伝達の活性化のための組成物及び方法 |
BR112017022076A2 (pt) * | 2015-04-13 | 2018-08-14 | Aduro Biotech, Inc. | fusões de mesotelina-variante iii de receptor de fator de crescimento epidérmico e métodos de uso das mesmas |
CN107980044A (zh) * | 2015-04-13 | 2018-05-01 | 艾杜罗生物科技公司 | 用于治疗癌症的免疫原性融合蛋白 |
US10455265B2 (en) * | 2015-04-27 | 2019-10-22 | Ericsson Ab | Program and device class entitlements in a media platform |
CN107847611A (zh) * | 2015-05-26 | 2018-03-27 | 阿德瓦希斯公司 | 个性化的基于递送载体的免疫疗法及其用途 |
CN108138099A (zh) * | 2015-06-24 | 2018-06-08 | 阿德瓦希斯公司 | 用于个性化的基于递送载体的免疫疗法的制造装置和方法 |
IL259931B2 (en) | 2015-12-16 | 2024-02-01 | Gritstone Bio Inc | Identification of neo-antigens, preparation, and use |
NL2017267B1 (en) | 2016-07-29 | 2018-02-01 | Aduro Biotech Holdings Europe B V | Anti-pd-1 antibodies |
EP3491009A4 (en) * | 2016-08-01 | 2020-03-04 | Aduro BioTech, Inc. | PROTEIN EXPRESSION AMPLIFIER SEQUENCES AND USE THEREOF |
NL2017270B1 (en) | 2016-08-02 | 2018-02-09 | Aduro Biotech Holdings Europe B V | New anti-hCTLA-4 antibodies |
CN111465989B (zh) | 2017-10-10 | 2024-06-25 | 磨石生物公司 | 使用热点进行的新抗原鉴别 |
CN111630602A (zh) | 2017-11-22 | 2020-09-04 | 磨石肿瘤生物技术公司 | 减少新抗原的接合表位呈递 |
WO2021014398A1 (en) * | 2019-07-23 | 2021-01-28 | University Of Rijeka Faculty Of Medicine | Integrated human cytomegalovirus / glioblastoma vaccine |
Family Cites Families (24)
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US5830702A (en) | 1990-10-31 | 1998-11-03 | The Trustees Of The University Of Pennsylvania | Live, recombinant listeria monocytogenes and production of cytotoxic T-cell response |
US5856457A (en) | 1991-03-29 | 1999-01-05 | Genentech, Inc. | Nucleic acids encoding a human IL-8 receptor |
IT1262895B (it) | 1992-03-02 | 1996-07-22 | Proteina estratta da ceppi citotossici di helicobacter pylori, gene che la esprime, uso della proteina come vaccino o diagnostico. | |
US6379943B1 (en) | 1999-03-05 | 2002-04-30 | Merck & Co., Inc. | High-efficiency Cre/loxp based system for construction of adenovirus vectors |
US5709999A (en) * | 1994-08-12 | 1998-01-20 | Myriad Genetics Inc. | Linked breast and ovarian cancer susceptibility gene |
US7794729B2 (en) * | 1994-11-08 | 2010-09-14 | The Trustees Of The University Of Pennsylvania | Methods and compositions for immunotherapy of cancer |
US6051237A (en) | 1994-11-08 | 2000-04-18 | The Trustees Of The University Of Pennsylvania | Specific immunotherapy of cancer using a live recombinant bacterial vaccine vector |
ATE262586T1 (de) * | 1994-11-28 | 2004-04-15 | Univ Jefferson | Fusion junction typ iii mutant egf rezeptor peptid-tumorvakzin |
WO1997003715A1 (en) | 1995-07-21 | 1997-02-06 | The General Hospital Corporation | Method and apparatus of enhancing the delivery of a pharmaceutical formulation |
US6099848A (en) | 1997-11-18 | 2000-08-08 | The Trustees Of The University Of Pennsylvania | Immunogenic compositions comprising DAL/DAT double-mutant, auxotrophic, attenuated strains of Listeria and their methods of use |
EP1401472A4 (en) * | 2001-05-25 | 2005-04-06 | Univ Jefferson | ALTERNATIVE SHAPING FORMS OF PROTEINS AS THE BASIS FOR MULTIPLE THERAPEUTIC MODALITIES |
JP2005527240A (ja) | 2002-05-29 | 2005-09-15 | ザ・レジェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア | 弱毒リステリア種とこれを使用する方法 |
JP2006521090A (ja) | 2002-07-12 | 2006-09-21 | ザ ジョンズ ホプキンス ユニバーシティー | メゾテリンワクチンおよびモデルシステム |
ES2382332T3 (es) | 2003-02-06 | 2012-06-07 | Aduro Biotech | Listeria atenuada para entrar en células no fagocíticas, vacunas que comprenden esta listeria y métodos de uso de las mismas |
AU2004224425B2 (en) | 2003-02-06 | 2010-06-24 | Aduro Biotech | Modified free-living microbes, vaccine compositions and methods of use thereof |
US7842289B2 (en) | 2003-12-24 | 2010-11-30 | Aduro Biotech | Recombinant nucleic acid molecules, expression cassettes, and bacteria, and methods of use thereof |
NZ567837A (en) * | 2005-11-02 | 2011-11-25 | Univ Texas | Concurrent chemotherapy and immunotherapy with EGFRvIII peptide and temozolomide |
WO2007117371A2 (en) | 2006-03-01 | 2007-10-18 | Anza Therapeutics, Inc. | Engineered listeria and methods of use thereof |
WO2007103225A2 (en) | 2006-03-01 | 2007-09-13 | Anza Therapeutics, Inc. | Engineered listeria and methods of use thereof |
WO2009012488A1 (en) * | 2007-07-19 | 2009-01-22 | Duke University | Assay for human anti-egrf variant iii antibodies |
WO2009143085A1 (en) | 2008-05-19 | 2009-11-26 | Anza Therapeutics, Inc. | Compositions comprising prfa*mutant listeria and methods of use thereof |
KR20110045010A (ko) * | 2008-07-24 | 2011-05-03 | 아두로 바이오테크 | C형 간염의 치료를 위한 조성물 및 방법 |
TWI543767B (zh) * | 2008-08-19 | 2016-08-01 | 腫瘤療法 科學股份有限公司 | Hig2與urlc10抗原決定位胜肽以及含此胜肽之疫苗 |
WO2012068360A1 (en) * | 2010-11-17 | 2012-05-24 | Aduro Biotech | Methods and compositions for inducing an immune response to egfrviii |
-
2011
- 2011-11-17 WO PCT/US2011/061164 patent/WO2012068360A1/en active Application Filing
- 2011-11-17 PT PT11841347T patent/PT2640842T/pt unknown
- 2011-11-17 LT LTEP11841347.5T patent/LT2640842T/lt unknown
- 2011-11-17 EP EP11841347.5A patent/EP2640842B1/en active Active
- 2011-11-17 JP JP2013540008A patent/JP5998370B2/ja not_active Expired - Fee Related
- 2011-11-17 US US13/988,076 patent/US9200057B2/en not_active Expired - Fee Related
- 2011-11-17 RS RS20180979A patent/RS57630B1/sr unknown
- 2011-11-17 HU HUE11841347A patent/HUE039747T2/hu unknown
- 2011-11-17 SI SI201131548T patent/SI2640842T1/sl unknown
- 2011-11-17 PL PL11841347T patent/PL2640842T3/pl unknown
- 2011-11-17 ES ES11841347.5T patent/ES2684684T3/es active Active
- 2011-11-17 DK DK11841347.5T patent/DK2640842T3/en active
- 2011-11-17 CN CN201180062129.XA patent/CN103415620B/zh not_active Expired - Fee Related
- 2011-11-17 CA CA2818353A patent/CA2818353A1/en not_active Abandoned
-
2015
- 2015-11-25 US US14/952,470 patent/US9775891B2/en not_active Expired - Fee Related
-
2017
- 2017-10-02 US US15/722,908 patent/US20180021420A1/en not_active Abandoned
-
2018
- 2018-08-23 HR HRP20181343TT patent/HRP20181343T1/hr unknown
- 2018-08-27 CY CY181100893T patent/CY1120622T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP2640842A4 (en) | 2014-04-09 |
CY1120622T1 (el) | 2019-12-11 |
CA2818353A1 (en) | 2012-05-24 |
US9200057B2 (en) | 2015-12-01 |
ES2684684T3 (es) | 2018-10-04 |
US20160074491A1 (en) | 2016-03-17 |
US20180021420A1 (en) | 2018-01-25 |
HRP20181343T1 (hr) | 2018-10-19 |
JP5998370B2 (ja) | 2016-09-28 |
HUE039747T2 (hu) | 2019-02-28 |
PT2640842T (pt) | 2018-10-12 |
EP2640842B1 (en) | 2018-05-30 |
DK2640842T3 (en) | 2018-08-13 |
LT2640842T (lt) | 2018-09-10 |
CN103415620A (zh) | 2013-11-27 |
PL2640842T3 (pl) | 2018-11-30 |
CN103415620B (zh) | 2016-10-12 |
US20140037662A1 (en) | 2014-02-06 |
EP2640842A1 (en) | 2013-09-25 |
US9775891B2 (en) | 2017-10-03 |
WO2012068360A1 (en) | 2012-05-24 |
JP2014504851A (ja) | 2014-02-27 |
RS57630B1 (sr) | 2018-11-30 |
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