SI2640842T1 - Postopki in sestavki za induciranje imunskega odziva na EGFRvIII - Google Patents

Postopki in sestavki za induciranje imunskega odziva na EGFRvIII

Info

Publication number
SI2640842T1
SI2640842T1 SI201131548T SI201131548T SI2640842T1 SI 2640842 T1 SI2640842 T1 SI 2640842T1 SI 201131548 T SI201131548 T SI 201131548T SI 201131548 T SI201131548 T SI 201131548T SI 2640842 T1 SI2640842 T1 SI 2640842T1
Authority
SI
Slovenia
Prior art keywords
egfrviii
inducing
compositions
methods
immune response
Prior art date
Application number
SI201131548T
Other languages
English (en)
Inventor
Peter M. Lauer
Keith Bahjat
Original Assignee
Aduro Biotech, Inc.
Providence Health & Services-Oregon D/B/A Providence Portland Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aduro Biotech, Inc., Providence Health & Services-Oregon D/B/A Providence Portland Medical Center filed Critical Aduro Biotech, Inc.
Publication of SI2640842T1 publication Critical patent/SI2640842T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001102—Receptors, cell surface antigens or cell surface determinants
    • A61K39/001103—Receptors for growth factors
    • A61K39/001104—Epidermal growth factor receptors [EGFR]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SI201131548T 2010-11-17 2011-11-17 Postopki in sestavki za induciranje imunskega odziva na EGFRvIII SI2640842T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41485010P 2010-11-17 2010-11-17
EP11841347.5A EP2640842B1 (en) 2010-11-17 2011-11-17 Methods and compositions for inducing an immune response to egfrviii
PCT/US2011/061164 WO2012068360A1 (en) 2010-11-17 2011-11-17 Methods and compositions for inducing an immune response to egfrviii

Publications (1)

Publication Number Publication Date
SI2640842T1 true SI2640842T1 (sl) 2018-09-28

Family

ID=46084412

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201131548T SI2640842T1 (sl) 2010-11-17 2011-11-17 Postopki in sestavki za induciranje imunskega odziva na EGFRvIII

Country Status (16)

Country Link
US (3) US9200057B2 (sl)
EP (1) EP2640842B1 (sl)
JP (1) JP5998370B2 (sl)
CN (1) CN103415620B (sl)
CA (1) CA2818353A1 (sl)
CY (1) CY1120622T1 (sl)
DK (1) DK2640842T3 (sl)
ES (1) ES2684684T3 (sl)
HR (1) HRP20181343T1 (sl)
HU (1) HUE039747T2 (sl)
LT (1) LT2640842T (sl)
PL (1) PL2640842T3 (sl)
PT (1) PT2640842T (sl)
RS (1) RS57630B1 (sl)
SI (1) SI2640842T1 (sl)
WO (1) WO2012068360A1 (sl)

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US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
ES2911677T3 (es) 2011-10-03 2022-05-20 Modernatx Inc Nucleósidos, nucleótidos y ácidos nucleicos modificados, y sus usos
DE12858350T1 (de) 2011-12-16 2021-10-07 Modernatx, Inc. Modifizierte mrna zusammensetzungen
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US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US10501512B2 (en) 2012-04-02 2019-12-10 Modernatx, Inc. Modified polynucleotides
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
US9770467B2 (en) 2012-06-08 2017-09-26 Aduro Biotech, Inc. Compositions and methods for cancer immunotherapy
SG10201610161UA (en) 2012-11-06 2017-01-27 Aduro Biotech Inc Facultatively attenuated bacterial species and methods of preparation and use thereof
US9597380B2 (en) 2012-11-26 2017-03-21 Modernatx, Inc. Terminally modified RNA
US9695212B2 (en) 2012-12-13 2017-07-04 Aduro Biotech, Inc. Compositions comprising cyclic purine dinucleotides having defined stereochemistries and methods for their preparation and use
CN104955835B (zh) 2012-12-27 2020-04-17 艾杜罗生物科技公司 促进抗原序列的李斯特菌表达的信号肽融合配偶体以及其制备和使用方法
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
US20140329889A1 (en) 2013-05-03 2014-11-06 The Regents Of The University Of California Cyclic di-nucleotide induction of type i interferon
CU24377B1 (es) 2013-05-18 2018-12-05 Aduro Biotech Inc Dinucléotidos de purina cíclicos y composiciones de los mismos útiles para inducir la producción de interferón de tipo i dependientes de sting
US9549944B2 (en) 2013-05-18 2017-01-24 Aduro Biotech, Inc. Compositions and methods for inhibiting “stimulator of interferon gene”—dependent signalling
US10023626B2 (en) 2013-09-30 2018-07-17 Modernatx, Inc. Polynucleotides encoding immune modulating polypeptides
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WO2015164121A1 (en) * 2014-04-24 2015-10-29 Advaxis, Inc. Recombinant listeria vaccine strains and methods of producing the same
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MX2017004729A (es) * 2014-10-14 2018-01-09 Univ Pennsylvania Terapia de combinacion para usar en la terapia contra el cancer.
WO2016073381A1 (en) 2014-11-03 2016-05-12 Cerus Corporation Compositions and methods for improved car-t cell therapies
JP6692826B2 (ja) 2015-03-10 2020-05-13 アドゥロ バイオテック，インク． 「インターフェロン遺伝子刺激因子」依存性シグナル伝達の活性化のための組成物及び方法
BR112017022076A2 (pt) * 2015-04-13 2018-08-14 Aduro Biotech, Inc. fusões de mesotelina-variante iii de receptor de fator de crescimento epidérmico e métodos de uso das mesmas
CN107980044A (zh) * 2015-04-13 2018-05-01 艾杜罗生物科技公司 用于治疗癌症的免疫原性融合蛋白
US10455265B2 (en) * 2015-04-27 2019-10-22 Ericsson Ab Program and device class entitlements in a media platform
CN107847611A (zh) * 2015-05-26 2018-03-27 阿德瓦希斯公司 个性化的基于递送载体的免疫疗法及其用途
CN108138099A (zh) * 2015-06-24 2018-06-08 阿德瓦希斯公司 用于个性化的基于递送载体的免疫疗法的制造装置和方法
IL259931B2 (en) 2015-12-16 2024-02-01 Gritstone Bio Inc Identification of neo-antigens, preparation, and use
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NL2017270B1 (en) 2016-08-02 2018-02-09 Aduro Biotech Holdings Europe B V New anti-hCTLA-4 antibodies
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CN111630602A (zh) 2017-11-22 2020-09-04 磨石肿瘤生物技术公司 减少新抗原的接合表位呈递
WO2021014398A1 (en) * 2019-07-23 2021-01-28 University Of Rijeka Faculty Of Medicine Integrated human cytomegalovirus / glioblastoma vaccine

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Also Published As

Publication number Publication date
EP2640842A4 (en) 2014-04-09
CY1120622T1 (el) 2019-12-11
CA2818353A1 (en) 2012-05-24
US9200057B2 (en) 2015-12-01
ES2684684T3 (es) 2018-10-04
US20160074491A1 (en) 2016-03-17
US20180021420A1 (en) 2018-01-25
HRP20181343T1 (hr) 2018-10-19
JP5998370B2 (ja) 2016-09-28
HUE039747T2 (hu) 2019-02-28
PT2640842T (pt) 2018-10-12
EP2640842B1 (en) 2018-05-30
DK2640842T3 (en) 2018-08-13
LT2640842T (lt) 2018-09-10
CN103415620A (zh) 2013-11-27
PL2640842T3 (pl) 2018-11-30
CN103415620B (zh) 2016-10-12
US20140037662A1 (en) 2014-02-06
EP2640842A1 (en) 2013-09-25
US9775891B2 (en) 2017-10-03
WO2012068360A1 (en) 2012-05-24
JP2014504851A (ja) 2014-02-27
RS57630B1 (sr) 2018-11-30

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