SI2136792T1 - Hot-melt micropellets - Google Patents

Hot-melt micropellets

Info

Publication number
SI2136792T1
SI2136792T1 SI200830924T SI200830924T SI2136792T1 SI 2136792 T1 SI2136792 T1 SI 2136792T1 SI 200830924 T SI200830924 T SI 200830924T SI 200830924 T SI200830924 T SI 200830924T SI 2136792 T1 SI2136792 T1 SI 2136792T1
Authority
SI
Slovenia
Prior art keywords
micropellets
melt
hot
melt micropellets
Prior art date
Application number
SI200830924T
Other languages
Slovenian (sl)
Inventor
Rok Dreu
Miha Homar
Mateja Burjak
Janez Kerc
Stanko Srcic
Original Assignee
Lek Pharmaceuticals D.D.
Rok Dreu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38241063&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2136792(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lek Pharmaceuticals D.D., Rok Dreu filed Critical Lek Pharmaceuticals D.D.
Publication of SI2136792T1 publication Critical patent/SI2136792T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SI200830924T 2007-03-19 2008-03-18 Hot-melt micropellets SI2136792T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07104410A EP1972336A1 (en) 2007-03-19 2007-03-19 Hot-melt micropellets
PCT/EP2008/053223 WO2008113803A1 (en) 2007-03-19 2008-03-18 Hot-melt micropellets
EP08717955A EP2136792B1 (en) 2007-03-19 2008-03-18 Hot-melt micropellets

Publications (1)

Publication Number Publication Date
SI2136792T1 true SI2136792T1 (en) 2013-11-29

Family

ID=38241063

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200830924T SI2136792T1 (en) 2007-03-19 2008-03-18 Hot-melt micropellets

Country Status (5)

Country Link
US (1) US20100172969A1 (en)
EP (2) EP1972336A1 (en)
PL (1) PL2136792T3 (en)
SI (1) SI2136792T1 (en)
WO (1) WO2008113803A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR1006780B (en) * 2009-04-10 2010-05-20 Specifar Abee ���������� ������� ��� ������������� ��������� Process for producing rapidly disintegrating spheroids (pellets), granules and/or mixtures therof.
US9510617B2 (en) 2012-04-13 2016-12-06 Frito-Lay North America, Inc. Micropellets of fine particle nutrients and methods of incorporating same into snack food products
US9271523B2 (en) 2012-05-23 2016-03-01 Dennis Williams Rotor assembly with one-piece finger member
RU2015114433A (en) * 2012-09-18 2016-11-10 МакНЕЙЛ-ППС, ИНК. ORAL DOSED FORMS WITH SLOW-RELEASE EXTRACTION CONTAINING PARTICLES OF EASY-MELTING DERIVATIVE PROPIONIC ACID
EP2897647A1 (en) * 2012-09-18 2015-07-29 McNeil-PPC, Inc. Suspension pharmaceutical formulations comprising low melting propionic acid derivative particles
US9630909B2 (en) 2013-06-27 2017-04-25 Mylan Laboratories Ltd Process for the preparation of nepafenac
EP3288556A4 (en) 2015-04-29 2018-09-19 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
CN105343033B (en) * 2015-12-14 2018-03-20 西南药业股份有限公司 A kind of ibuprofen slow-release micropill and preparation method thereof
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
CA3033065A1 (en) 2016-08-11 2018-02-15 Adamis Pharmaceuticals Corporation Drug compositions
EP3720844A4 (en) 2017-12-08 2021-08-11 Adamis Pharmaceuticals Corporation Drug compositions
FR3113238B1 (en) 2020-08-05 2024-04-05 Gattefosse Sas USE AS AN EXCIPIENT OF A MIXTURE OF LAURIC MACROGOLGLYCERIDE AND POLYETHYLENE GLYCOL

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI894611A (en) * 1988-09-30 1990-03-31 May & Baker Ltd GRANULAERA PHARMACEUTICAL PREPARATION.
US5084287A (en) * 1990-03-15 1992-01-28 Warner-Lambert Company Pharmaceutically useful micropellets with a drug-coated core and controlled-release polymeric coat
DE4118433C2 (en) * 1991-06-05 1994-12-01 Herbert Huettlin Fluid bed apparatus for treating particulate goods
FR2753904B1 (en) * 1996-10-01 1998-10-30 Gattefosse Ets Sa PHARMACEUTICAL COMPOSITION WITH MODIFIED RELEASE OF ACTIVE SUBSTANCE, INCLUDING A MATRIX, AND MANUFACTURING PROCESS
DE69811233T2 (en) * 1997-10-27 2003-11-20 Merck Patent Gmbh SOLID SOLUTIONS AND DISPERSIONS OF A POOR WATER-SOLUBLE ACTIVE SUBSTANCE
FR2811912B1 (en) * 2000-07-21 2003-02-07 Gattefosse Ets Sa PROCESS FOR COATING SOLID PARTICLES WITH A HEAT-MELTING AGENT, AND SOLID PARTICLES THUS COATED
US20060233873A1 (en) * 2003-01-24 2006-10-19 Julien Meissonnier Dispersion of taste masked crystals or granules of active substances, chewable soft capsules filled with said dispersion, and process for preparing same
WO2005048990A2 (en) * 2003-11-13 2005-06-02 Alza Corporation Melt blend dispersions comprising a low water solubility drug and an ethylene oxide-propylene oxide block copolymer
EP1750717B1 (en) * 2004-02-11 2017-07-19 Rubicon Research Private Limited Controlled release pharmaceutical compositions with improved bioavailability
CA2605792A1 (en) * 2005-04-25 2006-11-02 Teva Pharmaceuticals Usa, Inc. Extended release formulations

Also Published As

Publication number Publication date
EP2136792B1 (en) 2012-12-26
EP2136792A1 (en) 2009-12-30
PL2136792T3 (en) 2013-09-30
EP1972336A1 (en) 2008-09-24
US20100172969A1 (en) 2010-07-08
WO2008113803A1 (en) 2008-09-25

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