SI21223A - Farmacevtska formulacija s stabiliziranim amorfnim donepezilijevim kloridom - Google Patents
Farmacevtska formulacija s stabiliziranim amorfnim donepezilijevim kloridom Download PDFInfo
- Publication number
- SI21223A SI21223A SI200200155A SI200200155A SI21223A SI 21223 A SI21223 A SI 21223A SI 200200155 A SI200200155 A SI 200200155A SI 200200155 A SI200200155 A SI 200200155A SI 21223 A SI21223 A SI 21223A
- Authority
- SI
- Slovenia
- Prior art keywords
- donepezil
- pharmaceutically acceptable
- donepezil hydrochloride
- pharmaceutical formulation
- mixture
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
Priority Applications (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SI200200155A SI21223A (sl) | 2002-06-19 | 2002-06-19 | Farmacevtska formulacija s stabiliziranim amorfnim donepezilijevim kloridom |
PCT/SI2003/000019 WO2004000317A1 (en) | 2002-06-19 | 2003-06-18 | Pharmaceutical composition containing stabilised amorphous form of donepezil hydrochloride |
SI200331643T SI1513528T1 (sl) | 2002-06-19 | 2003-06-18 | Farmacevtski sestavek, ki vsebuje stabilizirano amorfno obliko donepezilijevega hidroklorida |
ES03741747T ES2326529T3 (es) | 2002-06-19 | 2003-06-18 | Composicion farmaceutica que contiene una forma amorfa estabilizada de clorhidrato de donepezil. |
DE60327696T DE60327696D1 (de) | 2002-06-19 | 2003-06-18 | Pharmazeutische zusammensetzung enthaltend stabilisierte amorphe form von donepezil hydrochlorid |
DK03741747T DK1513528T3 (da) | 2002-06-19 | 2003-06-18 | Farmaceutisk sammens tning indeholdende stabiliserede amorfe former af donepezilhydrochlorid |
EP03741747A EP1513528B1 (en) | 2002-06-19 | 2003-06-18 | Pharmaceutical composition containing stabilised amorphous form of donepezil hydrochloride |
AT03741747T ATE431739T1 (de) | 2002-06-19 | 2003-06-18 | Pharmazeutische zusammensetzung enthaltend stabilisierte amorphe form von donepezil hydrochlorid |
EA200500040A EA012904B1 (ru) | 2002-06-19 | 2003-06-18 | Фармацевтическая композиция, содержащая стабилизированную аморфную форму донепезил гидрохлорида |
AU2003279102A AU2003279102A1 (en) | 2002-06-19 | 2003-06-18 | Pharmaceutical composition containing stabilised amorphous form of donepezil hydrochloride |
PL372116A PL212584B1 (pl) | 2002-06-19 | 2003-06-18 | Kompozycja farmaceutyczna zawierajaca chlorowodorek donepezilu w bezpostaciowej formie i sposób jej wytwarzania, sposób wytwarzania bezpostaciowej formy chlorowodorku donepezilu i jego zastosowanie |
PT03741747T PT1513528E (pt) | 2002-06-19 | 2003-06-18 | Composição farmacêutica contendo forma amorfa estabilizada de cloridrato de donepezilo |
UAA200500514A UA86573C2 (ru) | 2002-06-19 | 2003-06-18 | Фармацевтическая композиция, которая содержит стабилизированную аморфную форму донепезила гидрохлорида |
YU110604A RS51824B (en) | 2002-06-19 | 2003-06-18 | PHARMACEUTICAL FORMULATION WITH STABILIZED AMORPHIC FORM OF DONEPESIL HYDROCHLORIDE |
HRP20041198AA HRP20041198B1 (hr) | 2002-06-19 | 2004-12-17 | Farmaceutski pripravci koji sadrže stabiliziranu amorfnu formu donepezil hidroklorida |
CY20091100878T CY1109314T1 (el) | 2002-06-19 | 2009-08-17 | Φαρμακευτικη συνθεση περιεχουσα σταθεροποιημενη αμορφη μορφη της υδροχλωρικης ντονεπεζιλης |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SI200200155A SI21223A (sl) | 2002-06-19 | 2002-06-19 | Farmacevtska formulacija s stabiliziranim amorfnim donepezilijevim kloridom |
Publications (1)
Publication Number | Publication Date |
---|---|
SI21223A true SI21223A (sl) | 2003-12-31 |
Family
ID=29778199
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200200155A SI21223A (sl) | 2002-06-19 | 2002-06-19 | Farmacevtska formulacija s stabiliziranim amorfnim donepezilijevim kloridom |
SI200331643T SI1513528T1 (sl) | 2002-06-19 | 2003-06-18 | Farmacevtski sestavek, ki vsebuje stabilizirano amorfno obliko donepezilijevega hidroklorida |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200331643T SI1513528T1 (sl) | 2002-06-19 | 2003-06-18 | Farmacevtski sestavek, ki vsebuje stabilizirano amorfno obliko donepezilijevega hidroklorida |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP1513528B1 (ru) |
AT (1) | ATE431739T1 (ru) |
AU (1) | AU2003279102A1 (ru) |
CY (1) | CY1109314T1 (ru) |
DE (1) | DE60327696D1 (ru) |
DK (1) | DK1513528T3 (ru) |
EA (1) | EA012904B1 (ru) |
ES (1) | ES2326529T3 (ru) |
HR (1) | HRP20041198B1 (ru) |
PL (1) | PL212584B1 (ru) |
PT (1) | PT1513528E (ru) |
RS (1) | RS51824B (ru) |
SI (2) | SI21223A (ru) |
UA (1) | UA86573C2 (ru) |
WO (1) | WO2004000317A1 (ru) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL150509A (en) | 2002-07-01 | 2007-07-04 | Joseph Kaspi | Pharmaceutical preparations containing donafazil hydrochloride |
IL154370A0 (en) * | 2003-02-10 | 2003-09-17 | Chemagis Ltd | Solid amorphous mixtures, processes for the preparation thereof and pharmaceutical compositions containing the same |
WO2005065645A2 (en) * | 2003-12-31 | 2005-07-21 | Actavis Group Hf | Donepezil formulations |
US8980894B2 (en) | 2004-03-25 | 2015-03-17 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure |
EP1579862A1 (en) | 2004-03-25 | 2005-09-28 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure |
IL171137A (en) | 2004-09-29 | 2012-01-31 | Chemagis Ltd | Use of purified malt donfazil for the preparation of pure pharmaceutical amorphous donfazil hydrochloride |
RS51271B (sr) * | 2004-10-19 | 2010-12-31 | Krka Tovarna Zdravil D.D. | Čvrsta farmaceutska kompozicija koja sadrži donepezil hidrohlorid |
WO2006063025A1 (en) * | 2004-12-07 | 2006-06-15 | Nektar Therapeutics | Stable non-crystalline formulation comprising donepezil |
US20060122226A1 (en) | 2004-12-08 | 2006-06-08 | Itai Adin | Crystalline forms of Donepezil base |
JP2008525313A (ja) | 2004-12-27 | 2008-07-17 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 抗痴呆薬の安定化方法 |
JP2007015934A (ja) * | 2005-07-05 | 2007-01-25 | Meiko Shoji Kk | 温感クリーム化粧料 |
DE102005060377A1 (de) | 2005-12-16 | 2007-06-21 | Ratiopharm Gmbh | Pharmazeutische Zusammensetzung enthaltend Donepezilhydrochlorid, Tablette hieraus und Verfahren zu deren Herstellung |
EP1920785A1 (en) | 2006-11-07 | 2008-05-14 | Boehringer Ingelheim Vetmedica Gmbh | Liquid preparation comprising a complex of pimobendan and cyclodextrin |
DE102007037932A1 (de) | 2007-08-11 | 2009-02-12 | Alfred E. Tiefenbacher Gmbh & Co.Kg | Donepezilhydrochlorid in amorpher Form enthaltende Tablette |
DE102009041839A1 (de) * | 2009-09-18 | 2011-03-24 | Dolorgiet Gmbh & Co. Kg | Donepezil-haltige Tabletten |
EP2366378A1 (en) | 2010-03-01 | 2011-09-21 | Dexcel Pharma Technologies Ltd. | Sustained-release donepezil formulations |
WO2011151359A1 (en) | 2010-06-02 | 2011-12-08 | Noscira, S.A. | Combined treatment with a cholinesterase inhibitor and a thiadiazolidinedione derivative |
EP2502620A1 (en) | 2011-03-24 | 2012-09-26 | Krka Tovarna Zdravil, D.D., Novo Mesto | Solid pharmaceutical composition comprising donepezil |
ES2924478T3 (es) | 2012-03-15 | 2022-10-07 | Boehringer Ingelheim Vetmedica Gmbh | Formulación de comprimidos farmacéuticos para el sector médico veterinario, método de producción y uso de los mismos |
EA034430B1 (ru) | 2013-07-19 | 2020-02-06 | Бёрингер Ингельхайм Ветмедика Гмбх | Жидкая водная фармацевтическая композиция с консервантами, содержащая этерифицированные производные циклодекстрина |
HUE056143T2 (hu) | 2013-12-04 | 2024-01-28 | Boehringer Ingelheim Vetmedica Gmbh | Pimobendán javított gyógyászati készítményei |
US20180344646A1 (en) * | 2015-11-25 | 2018-12-06 | Patheon Development Services Inc. | Amorphous dispersion granules and oral dosage forms |
US10537570B2 (en) | 2016-04-06 | 2020-01-21 | Boehringer Ingelheim Vetmedica Gmbh | Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease |
KR102372630B1 (ko) * | 2019-05-15 | 2022-03-14 | 주식회사 대웅제약 | 고함량의 도네페질 또는 그의 염을 포함하는 경피흡수제제 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2525108B1 (fr) * | 1982-04-19 | 1989-05-12 | Elan Corp Ltd | Medicaments a haut degre de solubilite et procede pour leur obtention |
RU2190603C2 (ru) * | 1996-06-07 | 2002-10-10 | Эйсай Ко., Лтд. | Полиморфные модификации донепезила гидрохлорида, способы их получения и способ лечения заболевания, сопровождающегося активностью ацетилхолинэстеразы |
ES2310164T3 (es) * | 1999-02-10 | 2009-01-01 | Pfizer Products Inc. | Dispositivo de liberacion controlada por la matriz. |
WO2001034119A2 (en) * | 1999-11-12 | 2001-05-17 | Abbott Laboratories | Inhibitors of crystallization in a solid dispersion |
-
2002
- 2002-06-19 SI SI200200155A patent/SI21223A/sl not_active IP Right Cessation
-
2003
- 2003-06-18 EA EA200500040A patent/EA012904B1/ru not_active IP Right Cessation
- 2003-06-18 RS YU110604A patent/RS51824B/en unknown
- 2003-06-18 DE DE60327696T patent/DE60327696D1/de not_active Expired - Lifetime
- 2003-06-18 AT AT03741747T patent/ATE431739T1/de active
- 2003-06-18 DK DK03741747T patent/DK1513528T3/da active
- 2003-06-18 PL PL372116A patent/PL212584B1/pl unknown
- 2003-06-18 EP EP03741747A patent/EP1513528B1/en not_active Expired - Lifetime
- 2003-06-18 SI SI200331643T patent/SI1513528T1/sl unknown
- 2003-06-18 AU AU2003279102A patent/AU2003279102A1/en not_active Abandoned
- 2003-06-18 PT PT03741747T patent/PT1513528E/pt unknown
- 2003-06-18 UA UAA200500514A patent/UA86573C2/ru unknown
- 2003-06-18 WO PCT/SI2003/000019 patent/WO2004000317A1/en not_active Application Discontinuation
- 2003-06-18 ES ES03741747T patent/ES2326529T3/es not_active Expired - Lifetime
-
2004
- 2004-12-17 HR HRP20041198AA patent/HRP20041198B1/hr not_active IP Right Cessation
-
2009
- 2009-08-17 CY CY20091100878T patent/CY1109314T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
ATE431739T1 (de) | 2009-06-15 |
AU2003279102A1 (en) | 2004-01-06 |
PL212584B1 (pl) | 2012-10-31 |
PT1513528E (pt) | 2009-08-18 |
PL372116A1 (en) | 2005-07-11 |
ES2326529T3 (es) | 2009-10-14 |
SI1513528T1 (sl) | 2009-10-31 |
UA86573C2 (ru) | 2009-05-12 |
DE60327696D1 (de) | 2009-07-02 |
HRP20041198A2 (en) | 2005-04-30 |
RS110604A (en) | 2007-02-05 |
EA012904B1 (ru) | 2010-02-26 |
EP1513528A1 (en) | 2005-03-16 |
RS51824B (en) | 2012-02-29 |
DK1513528T3 (da) | 2009-09-07 |
CY1109314T1 (el) | 2014-07-02 |
WO2004000317A1 (en) | 2003-12-31 |
EP1513528B1 (en) | 2009-05-20 |
EA200500040A1 (ru) | 2005-06-30 |
HRP20041198B1 (hr) | 2013-05-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
IF | Valid on the event date | ||
KO00 | Lapse of patent |
Effective date: 20120704 |