SI1666604T1 - Sestavki ortogonalnih parov lizil-tRNA in aminoacil-tRNA in aminoacil-tRNA-sintetaze in njihove uporabe - Google Patents

Sestavki ortogonalnih parov lizil-tRNA in aminoacil-tRNA in aminoacil-tRNA-sintetaze in njihove uporabe

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Publication number
SI1666604T1
SI1666604T1 SI200430690T SI200430690T SI1666604T1 SI 1666604 T1 SI1666604 T1 SI 1666604T1 SI 200430690 T SI200430690 T SI 200430690T SI 200430690 T SI200430690 T SI 200430690T SI 1666604 T1 SI1666604 T1 SI 1666604T1
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SI
Slovenia
Prior art keywords
trna
orthogonal
aminoacyl
compositions
lysyl
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Application number
SI200430690T
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English (en)
Inventor
Christopher J Anderson
Ning Wu
Stephen Santoro
Peter G Schultz
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Scripps Research Inst
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Publication of SI1666604T1 publication Critical patent/SI1666604T1/sl

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93Ligases (6)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SI200430690T 2003-07-07 2004-07-07 Sestavki ortogonalnih parov lizil-tRNA in aminoacil-tRNA in aminoacil-tRNA-sintetaze in njihove uporabe SI1666604T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US48545103P 2003-07-07 2003-07-07
US52881503P 2003-12-10 2003-12-10
US53714904P 2004-01-15 2004-01-15
EP06002989A EP1666604B1 (en) 2003-07-07 2004-07-07 Compositions of orthogonal lysyl-tRNA and aminoacyl-tRNA synthetase pairs and uses thereof

Publications (1)

Publication Number Publication Date
SI1666604T1 true SI1666604T1 (sl) 2008-08-31

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SI200430690T SI1666604T1 (sl) 2003-07-07 2004-07-07 Sestavki ortogonalnih parov lizil-tRNA in aminoacil-tRNA in aminoacil-tRNA-sintetaze in njihove uporabe

Country Status (14)

Country Link
US (4) US7638297B2 (sl)
EP (2) EP1649004A4 (sl)
JP (2) JP5192150B2 (sl)
CN (1) CN101076598B (sl)
AT (2) ATE386133T1 (sl)
AU (1) AU2004267359B2 (sl)
BR (1) BRPI0412272A (sl)
CA (1) CA2531146A1 (sl)
DE (2) DE602004027770D1 (sl)
ES (1) ES2301099T3 (sl)
MX (1) MXPA06000242A (sl)
PT (2) PT1666604E (sl)
SI (1) SI1666604T1 (sl)
WO (1) WO2005019415A2 (sl)

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