SI1461360T1 - Conjugates comprising an antibody specific for the ed-b domain of fibronectin and their use for the detection and treatment of tumours - Google Patents
Conjugates comprising an antibody specific for the ed-b domain of fibronectin and their use for the detection and treatment of tumoursInfo
- Publication number
- SI1461360T1 SI1461360T1 SI200331895T SI200331895T SI1461360T1 SI 1461360 T1 SI1461360 T1 SI 1461360T1 SI 200331895 T SI200331895 T SI 200331895T SI 200331895 T SI200331895 T SI 200331895T SI 1461360 T1 SI1461360 T1 SI 1461360T1
- Authority
- SI
- Slovenia
- Prior art keywords
- tumours
- fibronectin
- treatment
- domain
- conjugates
- Prior art date
Links
- 102000016359 Fibronectins Human genes 0.000 title abstract 2
- 108010067306 Fibronectins Proteins 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 238000001514 detection method Methods 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 238000003745 diagnosis Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
Abstract
The present invention relates to methods for diagnosis and treatment of tumours, using peptides for binding radionuclides. The peptides comprise an antigen- binding site for the extra domain B (ED-B) of fibronectin.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02000315 | 2002-01-03 | ||
US35870202P | 2002-02-25 | 2002-02-25 | |
PCT/EP2003/000009 WO2003055917A2 (en) | 2002-01-03 | 2003-01-02 | Conjugates comprising an antibody specific for the ed-b domain of fibronectin and their use for the detection and treatment of tumours |
EP03726977A EP1461360B1 (en) | 2002-01-03 | 2003-01-02 | Conjugates comprising an antibody specific for the ed-b domain of fibronectin and their use for the detection and treatment of tumours |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1461360T1 true SI1461360T1 (en) | 2010-12-31 |
Family
ID=35976951
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200331895T SI1461360T1 (en) | 2002-01-03 | 2003-01-02 | Conjugates comprising an antibody specific for the ed-b domain of fibronectin and their use for the detection and treatment of tumours |
Country Status (8)
Country | Link |
---|---|
KR (2) | KR20100077052A (en) |
AT (1) | ATE478095T1 (en) |
DE (1) | DE60333820D1 (en) |
DK (1) | DK1461360T3 (en) |
ES (1) | ES2346750T3 (en) |
PT (1) | PT1461360E (en) |
SI (1) | SI1461360T1 (en) |
ZA (1) | ZA200406162B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019070526A1 (en) | 2017-10-02 | 2019-04-11 | Battelle Energy Alliance, Llc | Methods and systems for the electrochemical reduction of carbon dioxide using switchable polarity materials |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI259837B (en) * | 1998-05-11 | 2006-08-11 | Eidgenossische Tech Hochscule | Specific binding molecules for scintigraphy, conjugates containing them and therapeutic method for treatment of angiogenesis |
-
2003
- 2003-01-02 SI SI200331895T patent/SI1461360T1/en unknown
- 2003-01-02 KR KR1020107013008A patent/KR20100077052A/en not_active Application Discontinuation
- 2003-01-02 KR KR1020047010498A patent/KR100998803B1/en not_active IP Right Cessation
- 2003-01-02 DK DK03726977.6T patent/DK1461360T3/en active
- 2003-01-02 DE DE60333820T patent/DE60333820D1/en not_active Expired - Lifetime
- 2003-01-02 PT PT03726977T patent/PT1461360E/en unknown
- 2003-01-02 ES ES03726977T patent/ES2346750T3/en not_active Expired - Lifetime
- 2003-01-02 AT AT03726977T patent/ATE478095T1/en not_active IP Right Cessation
-
2004
- 2004-08-02 ZA ZA200406162A patent/ZA200406162B/en unknown
Also Published As
Publication number | Publication date |
---|---|
KR20040073540A (en) | 2004-08-19 |
KR20100077052A (en) | 2010-07-06 |
DE60333820D1 (en) | 2010-09-30 |
PT1461360E (en) | 2010-11-23 |
KR100998803B1 (en) | 2010-12-06 |
ATE478095T1 (en) | 2010-09-15 |
DK1461360T3 (en) | 2010-11-15 |
ES2346750T3 (en) | 2010-10-20 |
ZA200406162B (en) | 2005-09-27 |
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