SI1044364T1 - Method for the quantification of solid-phase reactions using fluorine nmr - Google Patents

Method for the quantification of solid-phase reactions using fluorine nmr

Info

Publication number
SI1044364T1
SI1044364T1 SI9830891T SI9830891T SI1044364T1 SI 1044364 T1 SI1044364 T1 SI 1044364T1 SI 9830891 T SI9830891 T SI 9830891T SI 9830891 T SI9830891 T SI 9830891T SI 1044364 T1 SI1044364 T1 SI 1044364T1
Authority
SI
Slovenia
Prior art keywords
quantification
solid
phase reactions
fluorine nmr
nmr
Prior art date
Application number
SI9830891T
Other languages
Slovenian (sl)
Inventor
Vasant K Nagulapalli
Edward Orton
John E Airey
Paul H Krolikowski
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1997/023920 external-priority patent/WO1998029376A1/en
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Priority claimed from EP98966876A external-priority patent/EP1044364B8/en
Publication of SI1044364T1 publication Critical patent/SI1044364T1/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N24/00Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/12Hydrolysis
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/14Esterification
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/18Introducing halogen atoms or halogen-containing groups
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/18Introducing halogen atoms or halogen-containing groups
    • C08F8/20Halogenation
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/26Removing halogen atoms or halogen-containing groups from the molecule
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/30Introducing nitrogen atoms or nitrogen-containing groups
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/34Introducing sulfur atoms or sulfur-containing groups
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/34Introducing sulfur atoms or sulfur-containing groups
    • C08F8/36Sulfonation; Sulfation
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2800/00Copolymer characterised by the proportions of the comonomers expressed
    • C08F2800/20Copolymer characterised by the proportions of the comonomers expressed as weight or mass percentages
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2810/00Chemical modification of a polymer
    • C08F2810/20Chemical modification of a polymer leading to a crosslinking, either explicitly or inherently
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N24/00Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects
    • G01N24/08Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using nuclear magnetic resonance

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
SI9830891T 1997-12-17 1998-12-14 Method for the quantification of solid-phase reactions using fluorine nmr SI1044364T1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
PCT/US1997/023920 WO1998029376A1 (en) 1996-12-19 1997-12-17 Process for the solid phase synthesis of aldehydes, ketones, oximes, amines and hydroxamic acid compounds
US9056398P 1998-06-24 1998-06-24
US9055898P 1998-06-24 1998-06-24
EP98966876A EP1044364B8 (en) 1997-12-17 1998-12-14 Method for the quantification of solid-phase reactions using fluorine nmr
PCT/US1998/026512 WO1999031491A1 (en) 1997-12-17 1998-12-14 Method and reagents for the quantification of solid-phase reactions using fluorine nmr

Publications (1)

Publication Number Publication Date
SI1044364T1 true SI1044364T1 (en) 2008-06-30

Family

ID=26782415

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9830891T SI1044364T1 (en) 1997-12-17 1998-12-14 Method for the quantification of solid-phase reactions using fluorine nmr

Country Status (9)

Country Link
KR (1) KR100696305B1 (en)
CY (1) CY1106850T1 (en)
EA (1) EA002603B1 (en)
HK (1) HK1033357A1 (en)
IL (1) IL136718A (en)
OA (1) OA11427A (en)
PT (1) PT1044364E (en)
SI (1) SI1044364T1 (en)
UA (1) UA70937C2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100764892B1 (en) * 2006-03-13 2007-10-09 한국화학연구원 Quantitative method of chloride ion by 35-Chloride Nuclear Magnetic Resonance
CN104181185A (en) * 2013-05-27 2014-12-03 湖北航天化学技术研究所 Method for determining contents of monomers of ENB type ethylene-propylene-diene monomer rubber
CN108344762B (en) * 2018-02-23 2020-09-25 中国科学院长春应用化学研究所 Method for detecting polylactic acid content in degradable plastic product

Also Published As

Publication number Publication date
KR20010033217A (en) 2001-04-25
CY1106850T1 (en) 2012-05-23
KR100696305B1 (en) 2007-03-20
UA70937C2 (en) 2004-11-15
PT1044364E (en) 2007-08-23
OA11427A (en) 2004-04-21
IL136718A (en) 2007-07-04
EA002603B1 (en) 2002-06-27
EA200000658A1 (en) 2001-02-26
HK1033357A1 (en) 2001-08-24

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