SI0981527T1 - Salt of naphthyridine carboxylic acid derivative - Google Patents

Salt of naphthyridine carboxylic acid derivative

Info

Publication number: SI0981527T1
Authority: SI; Slovenia
Prior art keywords: salt; carboxylic acid; acid derivative; naphthyridine carboxylic; naphthyridine
Prior art date: 1997-03-21

Application number

SI9830418T

Other languages

Slovenian (sl)

Inventor

Ae Ri Kim

Jin Hwa Lee

Ki Sook Park

Jong Ryoo Choi

Tae Hee Lee

Jay Hyok Chang

Do Hyun Nam

Hoon Choi

Original Assignee

Lg Life Sciences Ltd.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-03-21

Filing date

1998-03-20

Publication date

2003-10-31

1998-03-20 Application filed by Lg Life Sciences Ltd. filed Critical Lg Life Sciences Ltd.

2003-10-31 Publication of SI0981527T1 publication Critical patent/SI0981527T1/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
- C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C309/04—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing only one sulfo group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Pulmonology (AREA)
Urology & Nephrology (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

SI9830418T 1997-03-21 1998-03-20 Salt of naphthyridine carboxylic acid derivative SI0981527T1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
KR19970009840		1997-03-21
EP98908300A EP0981527B1 (en)	1997-03-21	1998-03-20	Salt of naphthyridine carboxylic acid derivative
PCT/KR1998/000051 WO1998042705A1 (en)	1997-03-21	1998-03-20	Salt of naphthyridine carboxylic acid derivative

Publications (1)

Publication Number	Publication Date
SI0981527T1 true SI0981527T1 (en)	2003-10-31

Family

ID=19500439

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
SI9830595T SI1179533T1 (en)	1997-03-21	1998-03-20	Salt of naphthyridine carboxylic acid derivative
SI9830418T SI0981527T1 (en)	1997-03-21	1998-03-20	Salt of naphthyridine carboxylic acid derivative

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
SI9830595T SI1179533T1 (en)	1997-03-21	1998-03-20	Salt of naphthyridine carboxylic acid derivative

Country Status (39)

Country	Link
US (9)	US7700617B2 (en)
EP (2)	EP0981527B1 (en)
JP (3)	JP3759962B2 (en)
KR (1)	KR100266499B1 (en)
CN (1)	CN1131229C (en)
AP (1)	AP1331A (en)
AR (1)	AR012125A1 (en)
AT (2)	ATE257836T1 (en)
AU (1)	AU726634B2 (en)
BG (1)	BG63972B1 (en)
BR (1)	BR9808290A (en)
CA (1)	CA2283671C (en)
CZ (2)	CZ288673B6 (en)
DE (2)	DE69821147T2 (en)
DK (2)	DK0981527T3 (en)
DZ (1)	DZ2448A1 (en)
EA (1)	EA001674B1 (en)
ES (2)	ES2213669T3 (en)
HK (1)	HK1026698A1 (en)
HU (2)	HU227536B1 (en)
ID (1)	ID22681A (en)
IL (2)	IL131812A (en)
IN (1)	IN188178B (en)
IS (2)	IS2093B (en)
MA (1)	MA24500A1 (en)
MY (1)	MY137653A (en)
NO (1)	NO312515B1 (en)
NZ (1)	NZ337748A (en)
OA (1)	OA11161A (en)
PE (1)	PE67999A1 (en)
PL (1)	PL191815B1 (en)
PT (2)	PT981527E (en)
SA (1)	SA98181055B1 (en)
SI (2)	SI1179533T1 (en)
SK (1)	SK284107B6 (en)
TR (1)	TR199902313T2 (en)
UA (1)	UA56218C2 (en)
WO (1)	WO1998042705A1 (en)
ZA (1)	ZA982335B (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9820405D0 (en) *	1998-09-18	1998-11-11	Smithkline Beecham Plc	Process
TR200102699T2 (en) *	1999-03-19	2002-03-21	Knoll Gmbh	Treatment of chronic joint disorder (osteoarthritis)
US6262071B1 (en)	1999-06-29	2001-07-17	Smithkline Beecham Corporation	Methods of use of antimicrobial compounds against pathogenic amycoplasma bacteria
US6331550B1 (en)	1999-06-29	2001-12-18	Smithkline Beecham Corporation	Methods of use of quinolone compounds against anaerobic pathogenic bacteria
US6803376B1 (en)	1999-06-29	2004-10-12	Smithkline Beecham Corporation	Method of use of quinolone compounds against pneumococcal and haemophilus bacteria
CA2282066C (en)	1999-06-29	2010-09-07	Smithkline Beecham Corporation	Methods of use of quinolone compounds against atypical upper respiratory pathogenic bacteria
GB9920919D0 (en) *	1999-09-03	1999-11-10	Sb Pharmco Inc	Novel compound
GB9920917D0 (en) *	1999-09-03	1999-11-10	Sb Pharmco Inc	Novel process
JP2001097863A (en) *	1999-09-24	2001-04-10	Smithkline Beecham Corp	Use of fluoroquinolone compound against anaerobic pathogenic bacteria
WO2001021176A1 (en) *	1999-09-22	2001-03-29	Smithkline Beecham Corporation	Methods of use of fluoroquinolone compounds against bacteria
JP2001097891A (en) *	1999-09-24	2001-04-10	Smithkline Beecham Corp	Method for using fluoroquinolone compound against respiratory pathogenic bacterium
GR1003520B (en) *	1999-09-22	2001-01-22	Smithkline Beecham Plc	Methods of use of fluoroquinolone compounds against nosocornial gram negative pathogenic bacteria
JP2001097864A (en) *	1999-09-24	2001-04-10	Smithkline Beecham Corp	Use of fluoroquinolone compound against respiratory tract and urinary tract pathogenic bacteria
GR1003521B (en) *	1999-09-23	2001-01-22	Smithkline Beecham Plc	Methods of use of fluoroquinolone compounds against gram positive pathogenic bacteria
KR20010091379A (en) *	2000-03-15	2001-10-23	성재갑	Novel process for the preparation of quinoline carboxylic acid derivatives having 7-(4-aminomethyl-3-oxime)pyrrolidine substituent
SI1412078T1 (en)	2001-08-02	2009-04-30	Lg Life Sciences Ltd Lg Twin T	Processes for the production of amino-protected derivatives of 4-aminomethylene-pyrrolidin-3-one, gemifloxacin or a salt thereof
MXPA04005179A (en) *	2001-11-30	2004-08-11	Lg Life Sciences Ltd	A METHOD OF TREATING BACTERIAL INFECTIONS USING GEMIFLOXACIN OR A SALT THEREOF AND A beta -LACTAM ANTIBIOTIC.
KR100517638B1 (en)	2002-04-08	2005-09-28	주식회사 엘지생명과학	New process for preparing acid salts of Gemifloxacin
AR043880A1 (en) *	2003-04-22	2005-08-17	Solvay Pharm Gmbh	ACID MESILATE 4- (4.TRANS-HYDROXICICLOHEXIL) AMINO-2-PHENYL-7H-PIRROLO (2,3-D) PYRIMIDINE AND ITS POLYMORPHAS FORMS
US7834027B2 (en)	2005-06-15	2010-11-16	Hetero Drugs Limited	Gemifloxacin process and polymorphs
KR20130128483A (en) *	2006-03-07	2013-11-26	욱크하트 리미티드	Prodrugs of benzoquinolizine-2-carboxylic acid
WO2010001408A2 (en) *	2008-06-06	2010-01-07	Matrix Laboratories Ltd.	Novel polymorphic forms of gemifloxacin mesylate
WO2010146594A1 (en) *	2009-06-16	2010-12-23	Hetero Research Foundation	Novel polymorphs of gemifloxacin mesylate
EP2491921A1 (en)	2011-02-25	2012-08-29	Deva Holding Anonim Sirketi	Conservation of anhydrous form of gemifloxacin
RS56556B1 (en) *	2012-02-27	2018-02-28	Bristol Myers Squibb Co	N- (5s, 6s, 9r) - 5 -amino- 6 - (2, 3 - difluorophenyl) -6, 7, 8, 9 - tetrahydro - 5h - cyclohepta [b]pyridin-9 -yl- 4 - (2 - oxo-2, 3 - dihydro - 1h- imidazo [4, 5 -b]pyridin - 1 - yl) piperidine - 1 - carboxylate, hemisulfate salt
CZ2016104A3 (en) *	2016-02-24	2017-09-06	Zentiva, K.S.	Crystalline modifications of methyl (3Z)-3- {[(4-{methyl[(4-methylpiperazin-1yl)acetyl]amino}phenyl)amino](phenyl)methylidene}-2oxo-2,3-dihydro-1H-indole-6-carboxylate and the methods of their preparation

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR223983A1 (en)	1978-08-25	1981-10-15	Dainippon Pharmaceutical Co	A PROCEDURE FOR PREPARING 6-HALOGEN-4-OXO-7- (1-PIPERAZINYL) -1,8-NAFTIRIDIN-3-CARBOXYLIC ACID DERIVATIVES
ES512969A0 (en)	1981-06-11	1983-02-16	Warner Lambert Co	"A PROCEDURE FOR PREPARING SALTS OF NAFTIRIDINE AND CHINOLEIN COMPOUNDS".
IN162769B (en)	1984-11-13	1988-07-09	Kyorin Seiyaku Kk
NZ222047A (en)	1986-10-08	1991-01-29	Bristol Myers Co	Quinoline - or naphthyridine - carboxylic acid anti-bacterial agents
JPH01100165A (en)	1987-10-13	1989-04-18	Shionogi & Co Ltd	Oxime or hydroxylamine derivative based antimicrobial agent
US4920120A (en)	1988-01-25	1990-04-24	Warner-Lambert Company	Antibacterial agents
US4931446A (en) *	1988-03-23	1990-06-05	Abbott Laboratories	Antimicrobial for in-vitro diagnostic kits
CA1336090C (en) *	1988-08-31	1995-06-27	Isao Hayakawa	Spiro-substituted cyclic amines of quinolone derivatives
US5286723A (en) *	1988-08-31	1994-02-15	Daiichi Seiyaku Co., Ltd.	Spiro compound
PL166381B1 (en)	1989-08-16	1995-05-31	Pfizer	Method of obtaining novel substituted 7-azabicyclo quinolocarboxylic acids
US5276041A (en)	1991-11-08	1994-01-04	Kaken Pharmaceutical Co., Ltd.	Oxime derivatives
WO1993025545A1 (en)	1992-06-09	1993-12-23	Korea Research Institute Of Chemical Technology	Novel quinoline derivatives and processes for preparing the same
EP0688772B1 (en) *	1994-06-16	1999-05-06	LG Chemical Limited	Quinoline carboxylic acid derivatives having 7-(4-amino-methyl-3-oxime) pyrrolidine substituents and processes for their preparation
US5776944A (en) *	1994-06-16	1998-07-07	Lg Chemical Ltd.	7-(4-aminomethyl-3-methyloxyiminopyrroplidin-1-yl)-1-cyclopropyl-6-flu oro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid and the process for the preparation thereof
DE69531305T2 (en)	1994-10-20	2004-05-13	Wakunaga Seiyaku K.K.	PYRIDONE CARBOXYLATE DERIVATIVES OR SALTS THEREOF AND ANTIBACTERIAL COMPOSITIONS CONTAINING THEM AS AN ACTIVE COMPONENT
WO1996023775A1 (en)	1995-01-30	1996-08-08	Wakunaga Seiyaku Kabushiki Kaisha	Novel pyridonecarboxylic acid derivatives or salts thereof and antibacterial agent containing the same as active ingredient
US5763454A (en)	1995-06-06	1998-06-09	Pfizer, Inc.	Crystal form of anhydrous 7-( 1α,5α,6α!-6-amino-3-azabicyclo 3.1.0!hex-3-yl)-6-fluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo-1,8 naphthyridine-3-carboxylic acid, methanessulfonic acid salt
US20020032216A1 (en) *	1997-03-21	2002-03-14	Lg Chemical Ltd.	Salt of naphthyridine carboxylic acid derivative
KR100286874B1 (en) *	1998-03-04	2001-04-16	성재갑	Method for preparing protected 4-aminomethyl-pyrrolidone-3-on
GB9820405D0 (en)	1998-09-18	1998-11-11	Smithkline Beecham Plc	Process

1998
- 1998-03-17 MA MA25001A patent/MA24500A1/en unknown
- 1998-03-18 DZ DZ980058A patent/DZ2448A1/en active
- 1998-03-19 ZA ZA9802335A patent/ZA982335B/en unknown
- 1998-03-20 SI SI9830595T patent/SI1179533T1/en unknown
- 1998-03-20 ES ES01203507T patent/ES2213669T3/en not_active Expired - Lifetime
- 1998-03-20 DE DE69821147T patent/DE69821147T2/en not_active Expired - Lifetime
- 1998-03-20 WO PCT/KR1998/000051 patent/WO1998042705A1/en active IP Right Grant
- 1998-03-20 PT PT98908300T patent/PT981527E/en unknown
- 1998-03-20 SK SK1236-99A patent/SK284107B6/en not_active IP Right Cessation
- 1998-03-20 AT AT01203507T patent/ATE257836T1/en active
- 1998-03-20 HU HU0600401A patent/HU227536B1/en unknown
- 1998-03-20 EP EP98908300A patent/EP0981527B1/en not_active Expired - Lifetime
- 1998-03-20 KR KR1019980009717A patent/KR100266499B1/en active IP Right Grant
- 1998-03-20 AR ARP980101268A patent/AR012125A1/en active IP Right Grant
- 1998-03-20 CZ CZ19993282A patent/CZ288673B6/en not_active IP Right Cessation
- 1998-03-20 UA UA99095186A patent/UA56218C2/en unknown
- 1998-03-20 PE PE1998000202A patent/PE67999A1/en not_active Application Discontinuation
- 1998-03-20 CN CN98803576A patent/CN1131229C/en not_active Expired - Lifetime
- 1998-03-20 AU AU66366/98A patent/AU726634B2/en not_active Expired
- 1998-03-20 AT AT98908300T patent/ATE239724T1/en active
- 1998-03-20 JP JP54550098A patent/JP3759962B2/en not_active Expired - Lifetime
- 1998-03-20 EA EA199900855A patent/EA001674B1/en not_active IP Right Cessation
- 1998-03-20 EP EP01203507A patent/EP1179533B1/en not_active Expired - Lifetime
- 1998-03-20 DK DK98908300T patent/DK0981527T3/en active
- 1998-03-20 ID IDW991044A patent/ID22681A/en unknown
- 1998-03-20 TR TR1999/02313T patent/TR199902313T2/en unknown
- 1998-03-20 BR BR9808290-6A patent/BR9808290A/en not_active Application Discontinuation
- 1998-03-20 NZ NZ337748A patent/NZ337748A/en not_active IP Right Cessation
- 1998-03-20 PL PL335812A patent/PL191815B1/en unknown
- 1998-03-20 AP APAP/P/1999/001649A patent/AP1331A/en active
- 1998-03-20 SI SI9830418T patent/SI0981527T1/en unknown
- 1998-03-20 DK DK01203507T patent/DK1179533T3/en active
- 1998-03-20 IL IL131812A patent/IL131812A/en not_active IP Right Cessation
- 1998-03-20 HU HU0000728A patent/HU225412B1/en unknown
- 1998-03-20 ES ES98908300T patent/ES2198697T3/en not_active Expired - Lifetime
- 1998-03-20 DE DE69814378T patent/DE69814378T2/en not_active Expired - Lifetime
- 1998-03-20 CA CA002283671A patent/CA2283671C/en not_active Expired - Lifetime
- 1998-03-20 PT PT01203507T patent/PT1179533E/en unknown
- 1998-03-20 IL IL13181298A patent/IL131812A0/en active IP Right Grant
- 1998-03-21 MY MYPI98001236A patent/MY137653A/en unknown
- 1998-03-23 IN IN727DE1998 patent/IN188178B/en unknown
- 1998-03-25 SA SA98181055A patent/SA98181055B1/en unknown
1999
- 1999-09-14 IS IS5181A patent/IS2093B/en unknown
- 1999-09-20 OA OA9900213A patent/OA11161A/en unknown
- 1999-09-21 NO NO19994595A patent/NO312515B1/en not_active IP Right Cessation
- 1999-09-21 BG BG103750A patent/BG63972B1/en unknown
2000
- 2000-08-30 HK HK00105435A patent/HK1026698A1/en not_active IP Right Cessation
- 2000-10-03 CZ CZ20003641A patent/CZ288715B6/en not_active IP Right Cessation
2003
- 2003-05-07 JP JP2003128650A patent/JP4781614B2/en not_active Expired - Lifetime
2005
- 2005-07-21 IS IS7952A patent/IS2095B/en unknown
2006
- 2006-12-07 US US11/635,069 patent/US7700617B2/en not_active Expired - Fee Related
2008
- 2008-10-14 JP JP2008265345A patent/JP2009051851A/en not_active Withdrawn
2009
- 2009-01-09 US US12/318,845 patent/US20090182006A1/en not_active Abandoned
2010
- 2010-06-02 US US12/791,957 patent/US20100240694A1/en not_active Abandoned
2011
- 2011-04-11 US US13/083,685 patent/US20110312987A1/en not_active Abandoned
2012
- 2012-06-26 US US13/533,383 patent/US20130065917A1/en not_active Abandoned
2013
- 2013-10-25 US US14/063,117 patent/US20140187576A1/en not_active Abandoned
2015
- 2015-02-13 US US14/621,689 patent/US20150291585A1/en not_active Abandoned
2016
- 2016-01-15 US US14/996,765 patent/US20160264569A1/en not_active Abandoned
2017
- 2017-01-20 US US15/411,030 patent/US20170253588A1/en not_active Abandoned

Also Published As

Publication number	Publication date
SI1179533T1 (en)	2004-04-30
NO994595D0 (en)	1999-09-21
US20140187576A1 (en)	2014-07-03
CZ328299A3 (en)	2000-02-16
CN1251101A (en)	2000-04-19
IS7952A (en)	2005-07-21
CA2283671A1 (en)	1998-10-01
IS2093B (en)	2006-04-12
MA24500A1 (en)	1998-10-01
EP0981527B1 (en)	2003-05-07
ID22681A (en)	1999-12-09
IS5181A (en)	1999-09-14
US20090182006A1 (en)	2009-07-16
SA98181055B1 (en)	2006-10-11
JP2004002413A (en)	2004-01-08
HU0600401D0 (en)	2006-07-28
HK1026698A1 (en)	2000-12-22
CZ288715B6 (en)	2001-08-15
KR19980080504A (en)	1998-11-25
JP4781614B2 (en)	2011-09-28
PT981527E (en)	2003-09-30
UA56218C2 (en)	2003-05-15
EA199900855A1 (en)	2000-04-24
BG103750A (en)	2000-06-30
HUP0000728A2 (en)	2000-09-28
EP1179533B1 (en)	2004-01-14
US20170253588A1 (en)	2017-09-07
MY137653A (en)	2009-02-27
NZ337748A (en)	2001-03-30
HU227536B1 (en)	2011-08-29
US20150291585A1 (en)	2015-10-15
DE69821147D1 (en)	2004-02-19
US20110312987A1 (en)	2011-12-22
PE67999A1 (en)	1999-09-30
DE69821147T2 (en)	2004-11-11
EP1179533A2 (en)	2002-02-13
ZA982335B (en)	1999-11-23
DE69814378D1 (en)	2003-06-12
DE69814378T2 (en)	2004-02-26
EP1179533A3 (en)	2002-03-20
HUP0000728A3 (en)	2002-12-28
IS2095B (en)	2006-04-12
AR012125A1 (en)	2000-09-27
WO1998042705A1 (en)	1998-10-01
OA11161A (en)	2003-04-25
BR9808290A (en)	2000-05-16
DK0981527T3 (en)	2003-09-01
US20160264569A1 (en)	2016-09-15
US20100240694A1 (en)	2010-09-23
ES2198697T3 (en)	2004-02-01
CA2283671C (en)	2003-09-16
NO312515B1 (en)	2002-05-21
DZ2448A1 (en)	2003-01-11
JP2000510484A (en)	2000-08-15
AU6636698A (en)	1998-10-20
EA001674B1 (en)	2001-06-25
US20080039488A1 (en)	2008-02-14
US7700617B2 (en)	2010-04-20
AU726634B2 (en)	2000-11-16
CZ288673B6 (en)	2001-08-15
IN188178B (en)	2002-08-31
KR100266499B1 (en)	2000-12-01
PL191815B1 (en)	2006-07-31
US20130065917A1 (en)	2013-03-14
JP2009051851A (en)	2009-03-12
SK123699A3 (en)	2000-08-14
JP3759962B2 (en)	2006-03-29
EP0981527A1 (en)	2000-03-01
ATE257836T1 (en)	2004-01-15
DK1179533T3 (en)	2004-05-03
TR199902313T2 (en)	1999-12-21
AP9901649A0 (en)	1999-09-30
BG63972B1 (en)	2003-08-29
ATE239724T1 (en)	2003-05-15
NO994595L (en)	1999-09-21
ES2213669T3 (en)	2004-09-01
SK284107B6 (en)	2004-09-08
IL131812A0 (en)	2001-03-19
IL131812A (en)	2006-04-10
AP1331A (en)	2004-11-26
PL335812A1 (en)	2000-05-22
CN1131229C (en)	2003-12-17
PT1179533E (en)	2004-05-31
HU225412B1 (en)	2006-11-28
HUP0600401A3 (en)	2010-05-28

Publication	Publication Date	Title
IL131812A0 (en)	2001-03-19	Salt of naphthyridine carboxylic acid derivative
HK1043124A1 (en)	2002-09-06	Salt of naphthyridine carboxylic acid derivative.
PL351898A1 (en)	2003-06-30	O-substituted derivatives of carboxylic acids
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IL129135A0 (en)	2000-02-17	3-Alkoxyisoxazol-4- YL-substituted 2-amino carboxylic acid compounds
HU9600322D0 (en)	1996-04-29	Novel quinolone carboxylic acid derivatives
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HUP9801403A3 (en)	1998-10-28	Carboxylic acid derivatives preparation process
HUP9802329A3 (en)	1999-04-28	Carboxylic acid derivatives
HRP940833A2 (en)	1996-12-31	1-(2-fluorocyclopropyl)-quinoline- and naphthyridone carboxylic acid derivatives
IL122919A (en)	2001-01-28	Preparation of 1-alkyl-pyrazole-5- carboxylic acid esters
GB9907082D0 (en)	1999-05-19	The preparation of carboxylic acid derivatives
AU3076295A (en)	1996-02-16	Heterocyclyl-1-phenyl substituted quinolone carboxylic acids as antiviral agents
ZA989552B (en)	1999-04-22	Salt of bisphosphonic acid derivative
PL339304A1 (en)	2000-12-04	Method of obtaining derivatives of 1-phenylparazolin-3-carboxylic acid
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