SG46782A1 - Bicyclic-fused pyridines - Google Patents

Bicyclic-fused pyridines

Info

Publication number
SG46782A1
SG46782A1 SG1997002082A SG1997002082A SG46782A1 SG 46782 A1 SG46782 A1 SG 46782A1 SG 1997002082 A SG1997002082 A SG 1997002082A SG 1997002082 A SG1997002082 A SG 1997002082A SG 46782 A1 SG46782 A1 SG 46782A1
Authority
SG
Singapore
Prior art keywords
bicyclic
fused pyridines
pyridines
fused
Prior art date
Application number
SG1997002082A
Other languages
English (en)
Inventor
Arndt Brandes
Michael Logers
Gunter Schmidt
Rolf Angerbauer
Carsten Schmeck
Klaus-Dieter Bremm
Hilmar Bischoff
Delf Schmidt
Joachim Schuhmacher
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of SG46782A1 publication Critical patent/SG46782A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
SG1997002082A 1996-07-08 1997-06-18 Bicyclic-fused pyridines SG46782A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19627430A DE19627430A1 (de) 1996-07-08 1996-07-08 Bicyclisch kondensierte Pyridine

Publications (1)

Publication Number Publication Date
SG46782A1 true SG46782A1 (en) 1998-02-20

Family

ID=7799218

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1997002082A SG46782A1 (en) 1996-07-08 1997-06-18 Bicyclic-fused pyridines

Country Status (30)

Country Link
US (1) US6063788A (xx)
EP (1) EP0825185A1 (xx)
JP (1) JPH1067751A (xx)
KR (1) KR980009247A (xx)
CN (1) CN1172803A (xx)
AR (1) AR007716A1 (xx)
AU (1) AU722365B2 (xx)
BG (1) BG61972B1 (xx)
BR (1) BR9703886A (xx)
CA (1) CA2209609A1 (xx)
CO (1) CO4870759A1 (xx)
CZ (1) CZ214797A3 (xx)
DE (1) DE19627430A1 (xx)
EE (1) EE9700151A (xx)
HN (1) HN1997000082A (xx)
HR (1) HRP970331A2 (xx)
HU (1) HUP9701158A1 (xx)
ID (1) ID17659A (xx)
IL (1) IL121235A0 (xx)
MA (1) MA24261A1 (xx)
NO (1) NO308738B1 (xx)
NZ (1) NZ328260A (xx)
PE (1) PE87798A1 (xx)
PL (1) PL320954A1 (xx)
SG (1) SG46782A1 (xx)
SK (1) SK92697A3 (xx)
TN (1) TNSN97116A1 (xx)
TR (1) TR199700583A2 (xx)
YU (1) YU28897A (xx)
ZA (1) ZA976021B (xx)

Families Citing this family (35)

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US6268392B1 (en) 1994-09-13 2001-07-31 G. D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors
US6642268B2 (en) 1994-09-13 2003-11-04 G.D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors
US6262277B1 (en) 1994-09-13 2001-07-17 G.D. Searle And Company Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
NZ512537A (en) 1998-12-23 2003-11-28 G Combinations of ileal bile acid transport inhibitors and fibric acid derivatives for cardiovascular indications
BR9916486A (pt) 1998-12-23 2002-02-05 Searle Llc Combinações de inibidores do transporte de ácidos biliares no ìleo e inibidores da proteìna de transferência do ester colesteril para indicações cardiovasculares
DK1140190T3 (da) 1998-12-23 2002-12-23 Searle Llc Kombinationer af ileumgaldesyretransport-inhibitorer og galdesyre-sekvestreringsmidler til cardiovaskulære indikatorer
WO2000038722A1 (en) 1998-12-23 2000-07-06 G.D. Searle & Co. COMBINATIONS OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS AND HMG CoA REDUCTASE INHIBITORS FOR CARDIOVASCULAR INDICATIONS
PT1140185E (pt) 1998-12-23 2003-10-31 Searle Llc Combinacoes de inibidores de proteina de transferencia de ester de colesterilo com agentes sequestrantes de acido biliar para indicacoes cardiovasculares
EP1140184B1 (en) 1998-12-23 2003-06-04 G.D. Searle LLC. Combinations of cholesteryl ester transfer protein inhibitors and nicotinic acid derivatives for cardiovascular indications
NZ512534A (en) 1998-12-23 2003-11-28 G Combinations of cholesteryl ester transfer protein inhibitors and fibric acid derivatives for cardiovascular indications
US20010018446A1 (en) 1999-09-23 2001-08-30 G.D. Searle & Co. Substituted N-Aliphatic-N-Aromatictertiary-Heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity
US6924313B1 (en) 1999-09-23 2005-08-02 Pfizer Inc. Substituted tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity
US6723752B2 (en) 1999-09-23 2004-04-20 Pharmacia Corporation (R)-chiral halogenated substituted n-benzyl-n-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity
WO2001068637A2 (en) 2000-03-10 2001-09-20 Pharmacia Corporation Method for the preparation of tetrahydrobenzothiepines
US20040219619A1 (en) * 2000-07-21 2004-11-04 Ester Fernandez-Salas Methods of identifying compounds that alter toxin persistence and/or protease activity
US6958328B2 (en) * 2001-04-18 2005-10-25 Ortho-Mcneil Pharmaceutical, Inc Arylindenopyridines and related therapeutic and prophylactic methods
US20050239782A1 (en) * 2001-04-18 2005-10-27 Heintzelman Geoffrey R Arylindenopyridines and related therapeutic and prophylactic methods
US6903109B2 (en) 2001-04-18 2005-06-07 Ortho-Muniel Pharmaceutical, Inc. Arylindenopyridines and related therapeutic and prophylactic methods
ATE444060T1 (de) 2001-06-22 2009-10-15 Pfizer Prod Inc Pharmazeutische zusammensetzungen enthaltend dispersionen aus arzneistoffen und neutralen polymeren
EA006777B1 (ru) 2001-06-22 2006-04-28 Пфайзер Продактс Инк. Фармацевтические композиции адсорбатов аморфного лекарственного средства
JP2005518347A (ja) 2001-11-02 2005-06-23 ジー．ディー． サール エルエルシー 頂端ナトリウム共依存性胆汁酸輸送（ａｓｂｔ）およびタウロコール酸塩取り込みの阻害剤としての新規一および二フッ化ベンゾチエピン化合物
CA2471639A1 (en) 2002-01-17 2003-07-31 Pharmacia Corporation Novel alkyl/aryl hydroxy or keto thiepines.
ES2305434T3 (es) 2002-02-01 2008-11-01 Pfizer Products Inc. Composiciones framaceuticas de dispersiones amorfas de farmacos y materiales que forman microfases lipofilas.
US20040127510A1 (en) * 2002-04-16 2004-07-01 Heintzelman Geoffrey R. Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods
MXPA06001417A (es) 2003-08-04 2006-05-15 Pfizer Prod Inc Composiciones farmaceuticas de adsorbatos de farmacos amorfos y materiales que forman microfases lipofilas.
CL2004001884A1 (es) 2003-08-04 2005-06-03 Pfizer Prod Inc Procedimiento de secado por pulverizacion para la formacion de dispersiones solidas amorfas de un farmaco y polimeros.
MXPA06003357A (es) * 2003-09-26 2006-06-08 Japan Tobacco Inc Metodo para inhibir la produccion de lipoproteina remanente.
DK1670768T3 (da) 2003-10-08 2009-11-09 Lilly Co Eli Forbindelser og fremgangsmåder til at behandle dyslipidæmi
JP2007530550A (ja) 2004-03-26 2007-11-01 イーライ リリー アンド カンパニー 異脂肪血症を治療するための化合物および方法
ES2384980T3 (es) * 2004-12-18 2012-07-16 Bayer Pharma Aktiengesellschaft Derivados de tetrahidroquinolina sustituidos en 4 con cicloalquilo y su uso como medicamentos
EP1844078B1 (en) 2005-02-03 2016-09-28 Bend Research, Inc Pharmaceutical compositions with enhanced performance
BRPI0617621A2 (pt) 2005-10-21 2011-08-02 Novartis Ag combinação de compostos orgánicos
DE102006012548A1 (de) * 2006-03-18 2007-09-20 Bayer Healthcare Ag Substituierte Chromanol-Derivate und ihre Verwendung
PA8801401A1 (es) * 2007-10-25 2009-05-15 Janssen Pharmaceutica Nv Arilindenopirimidinas y su uso como adenosina a2a
US20130156720A1 (en) 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5169857A (en) * 1988-01-20 1992-12-08 Bayer Aktiengesellschaft 7-(polysubstituted pyridyl)-hept-6-endates useful for treating hyperproteinaemia, lipoproteinaemia or arteriosclerosis
GB8626344D0 (en) * 1986-11-04 1986-12-03 Zyma Sa Bicyclic compounds
NO177005C (no) * 1988-01-20 1995-07-05 Bayer Ag Analogifremgangsmåte for fremstilling av substituerte pyridiner, samt mellomprodukter til bruk ved fremstillingen
IE892088L (en) * 1988-07-12 1990-01-12 William Henry Deryk Morris Quinoline derivatives, their production and use
NZ237097A (en) * 1990-02-26 1993-12-23 Squibb & Sons Inc Pyridine derivatives substituted in the 3-position by a phosphinic moiety.
JPH059179A (ja) * 1990-09-27 1993-01-19 Takeda Chem Ind Ltd 複素環化合物、その製造法及びａｃａｔ阻害剤

Also Published As

Publication number Publication date
DE19627430A1 (de) 1998-01-15
NO973144D0 (no) 1997-07-07
HU9701158D0 (en) 1997-09-29
CN1172803A (zh) 1998-02-11
TR199700583A2 (xx) 1998-01-21
MA24261A1 (fr) 1998-04-01
BR9703886A (pt) 1998-11-03
AU2844897A (en) 1998-01-15
YU28897A (xx) 2000-03-21
PL320954A1 (en) 1998-01-19
EP0825185A1 (de) 1998-02-25
ID17659A (id) 1998-01-15
SK92697A3 (en) 1998-02-04
CZ214797A3 (cs) 1998-01-14
US6063788A (en) 2000-05-16
BG101746A (en) 1998-03-31
HRP970331A2 (en) 1998-08-31
JPH1067751A (ja) 1998-03-10
PE87798A1 (es) 1999-02-13
EE9700151A (et) 1998-02-16
IL121235A0 (en) 1998-01-04
HN1997000082A (es) 1997-12-26
TNSN97116A1 (fr) 2005-03-15
CO4870759A1 (es) 1999-12-27
CA2209609A1 (en) 1998-01-08
HUP9701158A1 (hu) 1999-09-28
AR007716A1 (es) 1999-11-10
BG61972B1 (bg) 1998-11-30
AU722365B2 (en) 2000-08-03
NO973144L (no) 1998-01-09
KR980009247A (ko) 1998-04-30
ZA976021B (en) 1998-02-02
NO308738B1 (no) 2000-10-23
NZ328260A (en) 1998-09-24

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