SG11202113345WA - Cgrp antagonist compounds - Google Patents

Cgrp antagonist compounds

Info

Publication number
SG11202113345WA
SG11202113345WA SG11202113345WA SG11202113345WA SG11202113345WA SG 11202113345W A SG11202113345W A SG 11202113345WA SG 11202113345W A SG11202113345W A SG 11202113345WA SG 11202113345W A SG11202113345W A SG 11202113345WA SG 11202113345W A SG11202113345W A SG 11202113345WA
Authority
SG
Singapore
Prior art keywords
antagonist compounds
cgrp antagonist
cgrp
compounds
antagonist
Prior art date
Application number
SG11202113345WA
Inventor
Giles Albert Brown
Miles Stuart Congreve
Stephen Paul Watson
Julie Cansfield
Michael Alistair O'brien
Francesca Deflorian
Gregory R Ott
Nigel Alan Swain
Andrew David Cansfield
Original Assignee
Heptares Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heptares Therapeutics Ltd filed Critical Heptares Therapeutics Ltd
Publication of SG11202113345WA publication Critical patent/SG11202113345WA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SG11202113345WA 2019-06-12 2020-06-12 Cgrp antagonist compounds SG11202113345WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1908430.0A GB201908430D0 (en) 2019-06-12 2019-06-12 Cgrp antagonist compounds
PCT/GB2020/051429 WO2020249970A1 (en) 2019-06-12 2020-06-12 Cgrp antagonist compounds

Publications (1)

Publication Number Publication Date
SG11202113345WA true SG11202113345WA (en) 2021-12-30

Family

ID=67386293

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202113345WA SG11202113345WA (en) 2019-06-12 2020-06-12 Cgrp antagonist compounds

Country Status (12)

Country Link
US (1) US20220251110A1 (en)
EP (1) EP3983417A1 (en)
JP (1) JP2022535994A (en)
KR (1) KR20220020907A (en)
CN (1) CN114245797A (en)
AU (1) AU2020291160A1 (en)
BR (1) BR112021025103A2 (en)
CA (1) CA3143124A1 (en)
GB (1) GB201908430D0 (en)
IL (1) IL288875A (en)
SG (1) SG11202113345WA (en)
WO (1) WO2020249970A1 (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2438067B1 (en) * 2009-06-05 2015-08-26 Boehringer Ingelheim International GmbH Spirolactams as cgrp-antagonists
CA2816974A1 (en) * 2010-11-12 2012-05-18 Merck Sharp & Dohme Corp. Piperidinone carboxamide indane cgrp receptor antagonists
TWI501968B (en) * 2010-11-12 2015-10-01 Merck Sharp & Dohme Piperidinone carboxamide azaindane cgrp receptor antagonists

Also Published As

Publication number Publication date
US20220251110A1 (en) 2022-08-11
IL288875A (en) 2022-02-01
EP3983417A1 (en) 2022-04-20
CA3143124A1 (en) 2020-12-17
BR112021025103A2 (en) 2022-02-15
JP2022535994A (en) 2022-08-10
WO2020249970A1 (en) 2020-12-17
KR20220020907A (en) 2022-02-21
GB201908430D0 (en) 2019-07-24
CN114245797A (en) 2022-03-25
AU2020291160A1 (en) 2022-01-06

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