SG11202110889WA - Dosage forms and regimens for amino acid compounds - Google Patents

Dosage forms and regimens for amino acid compounds

Info

Publication number
SG11202110889WA
SG11202110889WA SG11202110889WA SG11202110889WA SG11202110889WA SG 11202110889W A SG11202110889W A SG 11202110889WA SG 11202110889W A SG11202110889W A SG 11202110889WA SG 11202110889W A SG11202110889W A SG 11202110889WA SG 11202110889W A SG11202110889W A SG 11202110889WA
Authority
SG
Singapore
Prior art keywords
regimens
amino acid
dosage forms
acid compounds
compounds
Prior art date
Application number
SG11202110889WA
Inventor
Jacob Cha
Chengguo Dong
Timothy Hom
Lan Jiang
Katerina Leftheris
Hui Li
Jr David J Morgans
Manuel Munoz
Maureen Reilly
Yajun Zheng
Martin Decaris
Scott Turner
Original Assignee
Pliant Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliant Therapeutics Inc filed Critical Pliant Therapeutics Inc
Publication of SG11202110889WA publication Critical patent/SG11202110889WA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/5025Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/502Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG11202110889WA 2019-04-08 2020-04-08 Dosage forms and regimens for amino acid compounds SG11202110889WA (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962831060P 2019-04-08 2019-04-08
US201962850530P 2019-05-20 2019-05-20
US201962899071P 2019-09-11 2019-09-11
PCT/US2020/027335 WO2020210404A1 (en) 2019-04-08 2020-04-08 Dosage forms and regimens for amino acid compounds

Publications (1)

Publication Number Publication Date
SG11202110889WA true SG11202110889WA (en) 2021-10-28

Family

ID=72750659

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202110889WA SG11202110889WA (en) 2019-04-08 2020-04-08 Dosage forms and regimens for amino acid compounds

Country Status (9)

Country Link
US (2) US11419869B2 (en)
EP (1) EP3952902A4 (en)
JP (1) JP2022526818A (en)
CN (1) CN114173803A (en)
AU (1) AU2020273158A1 (en)
CA (1) CA3136745A1 (en)
IL (1) IL287004A (en)
SG (1) SG11202110889WA (en)
WO (1) WO2020210404A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201823208A (en) 2016-09-07 2018-07-01 美商普萊恩醫療公司 N-acyl amino acid compounds and methods of use
WO2018119087A1 (en) 2016-12-23 2018-06-28 Pliant Therapeutics, Inc. Amino acid compounds and methods of use
TW201835078A (en) 2017-02-28 2018-10-01 美商萊築理公司 Inhibitors of [alpha]v[beta]6 integrin
CA3054792A1 (en) 2017-02-28 2018-09-07 Morphic Therapeutic, Inc. Inhibitors of .alpha.v.beta.6 integrin
PL3761980T3 (en) 2018-03-07 2024-06-10 Pliant Therapeutics, Inc. Amino acid compounds and methods of use
MX2020014086A (en) 2018-06-27 2021-04-13 Pliant Therapeutics Inc Amino acid compounds with unbranched linkers and methods of use.
BR112021003859A2 (en) 2018-08-29 2021-05-18 Morphic Therapeutic, Inc. inhibiting avss6 integrin
TW202028179A (en) 2018-10-08 2020-08-01 美商普萊恩醫療公司 Amino acid compounds and methods of use
SG11202110889WA (en) 2019-04-08 2021-10-28 Pliant Therapeutics Inc Dosage forms and regimens for amino acid compounds
KR20230121761A (en) * 2020-11-19 2023-08-21 플라이언트 테라퓨틱스, 인크. Integrin inhibitors and uses thereof
WO2022165000A1 (en) * 2021-01-27 2022-08-04 Shy Therapeutics, Llc Methods for the treatment of fibrotic disease
WO2022164997A1 (en) * 2021-01-27 2022-08-04 Shy Therapeutics, Llc Methods for the treatment of fibrotic disease
IL308063A (en) * 2021-04-30 2023-12-01 Pliant Therapeutics Inc Expanded dosage regimens for integrin inhibitors
US20230293519A1 (en) * 2021-10-14 2023-09-21 Pliant Therapeutics, Inc. Integrin inhibitors and uses thereof in combination with other agents
WO2023225119A1 (en) * 2022-05-18 2023-11-23 Pliant Therapeutics, Inc. Stabilization of integrin inhibitors
WO2024015717A2 (en) * 2022-07-09 2024-01-18 Pliant Therapeutics, Inc. Integrin inhibitors and uses thereof in combination with other agents
WO2024119067A1 (en) 2022-12-02 2024-06-06 Neumora Therapeutics, Inc. Methods of treating neurological disorders
WO2024125634A1 (en) * 2022-12-16 2024-06-20 西藏海思科制药有限公司 Tetrahydronaphthyridine compound and application thereof in medicine

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EE200000362A (en) 1997-12-17 2001-12-17 Merck & Co., Inc. Integrin receptor antagonists, a pharmaceutical composition and a process for its preparation
US6048861A (en) 1997-12-17 2000-04-11 Merck & Co., Inc. Integrin receptor antagonists
US7144897B2 (en) 2001-06-01 2006-12-05 Elan Oharmaceuticals, Inc. Hydroxy alkyl amines
JP2005538177A (en) 2002-09-10 2005-12-15 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー Substituted amino ether compounds for the treatment of Alzheimer's disease
ES2647585T3 (en) * 2012-07-18 2017-12-22 Saint Louis University Beta amino acid derivatives as integrin antagonists
AU2014324426A1 (en) 2013-09-30 2016-04-21 The Regents Of The University Of California Anti-alphavbeta1 integrin compounds and methods
CA2981371A1 (en) 2015-03-10 2016-09-15 The Regents Of The University Of California Anti-alphavbeta1 integrin inhibitors and methods of use
AU2017248750B2 (en) 2016-04-14 2021-12-02 Mars, Incorporated Compounds that modulate calcium-sensing receptor activity for modulating kokumi taste and pet food products containing the same
CA3029829A1 (en) * 2016-07-05 2018-01-11 The Rockefeller University Tetrahydronaphthyridinepentanamide integrin antagonists
TW201823208A (en) 2016-09-07 2018-07-01 美商普萊恩醫療公司 N-acyl amino acid compounds and methods of use
WO2018119087A1 (en) 2016-12-23 2018-06-28 Pliant Therapeutics, Inc. Amino acid compounds and methods of use
PL3761980T3 (en) * 2018-03-07 2024-06-10 Pliant Therapeutics, Inc. Amino acid compounds and methods of use
MX2020014086A (en) 2018-06-27 2021-04-13 Pliant Therapeutics Inc Amino acid compounds with unbranched linkers and methods of use.
TW202028179A (en) 2018-10-08 2020-08-01 美商普萊恩醫療公司 Amino acid compounds and methods of use
SG11202110889WA (en) 2019-04-08 2021-10-28 Pliant Therapeutics Inc Dosage forms and regimens for amino acid compounds
IL297969A (en) 2020-05-07 2023-01-01 Pliant Therapeutics Inc Treatment of respiratory diseases with amino acid compounds

Also Published As

Publication number Publication date
CN114173803A (en) 2022-03-11
US20230117605A1 (en) 2023-04-20
IL287004A (en) 2021-12-01
WO2020210404A1 (en) 2020-10-15
US11419869B2 (en) 2022-08-23
EP3952902A1 (en) 2022-02-16
AU2020273158A1 (en) 2021-11-11
CA3136745A1 (en) 2020-10-15
US20200352942A1 (en) 2020-11-12
JP2022526818A (en) 2022-05-26
EP3952902A4 (en) 2022-12-21

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